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1
Lograsso, Anthony. "Cure/Repeat/Cure." Bowling Green State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1556546784827036.
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DeStefano, Michele, Hendrik Schneider, and Michael Lindemann. "Editorial: Cure or curse? Compliance in digital healthcare." Universität Leipzig, 2018. https://ul.qucosa.de/id/qucosa%3A32050.
Full textAbstract:
The edition features first-rate articles by specialists in the field of healthcare
and data security. Apart from that we will face some classical compliance topics
and last but not least CEJ Founder Michele DeStefanos new book Legal Upheaval
will be introduced and reviewed.
3
Tsakoumagos, Nicole. "Fight/Cure." Cleveland State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=csu1622640775978268.
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4
Game, R. L. "A depth of cure test for visible light cured restorative resins /." Title page, contents and abstract only, 1991. http://web4.library.adelaide.edu.au/theses/09DM/09dmg192.pdf.
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5
Wood, William E. "Depression a cure /." Portland, Or. : Theological Research Exchange Network (TREN), 2005. http://www.tren.com.
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6
Somanath, Nagendra. "A finite element cure model and cure cycle optimization for composite structures." Thesis, This resource online, 1987. http://scholar.lib.vt.edu/theses/available/etd-04272010-020304/.
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7
Contini, Andrea. "Où "habite" la cure ? : la conception de la cure dans la Daseinanalyse." Paris 12, 2006. https://athena.u-pec.fr/primo-explore/search?query=any,exact,990002460040204611&vid=upec.
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Plus on cherche à approcher l'essence de la cure par la raison plus la raison elle-même nous montre ses limites. Le symptôme et sa genèse à partir du corps-sujet, autrement dit de la "chair (Leib", ce n'est qu'après qu'il devient manifeste dans le corps-objet ("Körper"). Cela nous fait comprendre que la disparition du symptôme au niveau du corps-objet ne présuppose pas la disparition du "symptôme au niveau de la chair". La cure est alors invisible. Pour nous orienter vers la cure, il est nécessaire de se pencher sur la "Lebenswelt", soit sur la pré-réflexivité et sur l'affectivité en même temps. Il est nécessaire de réfléchir sur le rythme du patient et du médecin durant la relation thérapeutique. Leurs rythmes s'entrecoisent à un niveau pré-réflexif : cela permet au patient l' "incarnation du sens" vécu dans la relation thérapeutiqueThe more we search for the essence of the cure through reason, the more the reason itself shows its limits. To understand what a cure is, it's necessary to study the "Lebenswelt". The symptom are born in the body and in the flesh ("chair") and only later it will be express in the body as "Körper". We understand that the disappearance of the "Körper" symptom does not necessary lead to the disappearance of the flesh symptom. Then, it appears that cure is invisible. For understanding the cure, we have to study the "Lebenswelt", the pre-reflexivity, and the affect in the same time. It is necessary to reflect on the rhythm of the patient and the doctor during the therapeutic relation. Their rhythms intersect on a pre-reflexive level : that allows to the patient the "incarnation of the meaning" lived in the therapeutic relation
8
Contini, Andrea Naudin Jean Escoubas Éliane. "Où "habite" la cure ? la conception de la cure dans la Daseinanalyse /." Créteil : Université de Paris-Val-de-Marne, 2006. http://doxa.scd.univ-paris12.fr:80/theses/th0246004.pdf.
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9
Tang, Yanyan. "Stereolithography Cure Process Modeling." Diss., Georgia Institute of Technology, 2005. http://hdl.handle.net/1853/7235.
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Although stereolithography (SL) is a remarkable improvement over conventional prototyping production, it is being pushed aggressively for improvements in both speed and resolution. However, it is not clear currently how these two features can be improved simultaneously and what the limits are for such optimization.
In order to address this issue a quantitative SL cure process model is developed which takes into account all the sub-processes involved in SL: exposure, photoinitiation, photopolymerizaion, mass and heat transfer. To parameterize the model, the thermal and physical properties of a model compound system, ethoxylated (4) pentaerythritol tetraacrylate (E4PETeA) with 2,2-dimethoxy-2-phenylacetophenone (DMPA) as initiator, are determined. The free radical photopolymerization kinetics is also characterized by differential photocalorimetry (DPC) and a comprehensive kinetic model parameterized for the model material. The SL process model is then solved using the finite element method in the software package, FEMLAB, and validated by the capability of predicting fabricated part dimensions.
The SL cure process model, also referred to as the degree of cure (DOC) threshold model, simulates the cure behavior during the SL fabrication process, and provides insight into the part building mechanisms. It predicts the cured part dimension within 25% error, while the prediction error of the exposure threshold model currently utilized in SL industry is up to 50%. The DOC threshold model has been used to investigate the effects of material and process parameters on the SL performance properties, such as resolution, speed, maximum temperature rise in the resin bath, and maximum DOC of the green part. The effective factors are identified and parameter optimization is performed, which also provides guidelines for SL material development as well as process and laser improvement.
10
Tang, Yanyan. "Sterolithography (SL) cure modeling." Thesis, Georgia Institute of Technology, 2002. http://hdl.handle.net/1853/10143.
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11
Bonebreak, David. "Comparison in shear bond strengths between a light-cure and chemical-cure adhesive when used with a dual-cure self-etching primer." Thesis, NSUWorks, 2010. https://nsuworks.nova.edu/hpd_cdm_stuetd/35.
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12
Dang-Tran, Khuê-My. "Cure hydrique et obésité : cure hydrique avec eau de Volvic étudiée en milieu hospitalier." Bordeaux 2, 1994. http://www.theses.fr/1994BOR2M044.
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13
Perricone, Nicholas Chung Yu-ching. "The wrinkel [i.e. wrinkle] cure /." Monterey, Calif. : Monterey Institute of International Studies, 2002. http://library.miis.edu/thesis/TI03%5F1.pdf.
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14
Dei, Rossi Alice <1993>. "Cure Palliative e Servizio Sociale." Master's Degree Thesis, Università Ca' Foscari Venezia, 2017. http://hdl.handle.net/10579/11684.
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In questa tesi parlerò delle cure palliative e del relativo ruolo del servizio sociale. Inizierò ripercorrendo il concetto di morte lungo i secoli per giungere a vedere il suo significato ai giorni nostri. Mi soffermerò poi su 4 autori che hanno dato un contributo fondamentale allo sviluppo delle cure palliative e degli hospice. Successivamente spiegherò brevemente il significato di cure palliative e come sono nate e si sono sviluppate nel mondo e in particolare in Italia. Infine mi soffermerò sul ruolo del servizio sociale e degli assistenti sociali negli hospice e concluderò la tesi parlando di un hospice.
15
Soltani, Seyed Rouhallah Alavi. "Thermal, rheological, and mechanical properties of a polymer composite cured at staged cure cycles." Diss., Wichita State University, 2010. http://hdl.handle.net/10057/3289.
Full textAbstract:
Thermal, rheological, and mechanical properties of a polymer composite cured at
different one-stage and two-stage cure cycles were studied in this dissertation. A commercial
carbon-fiber prepreg, Cycom 977-2 UD, was used. This curing-toughened epoxy resin prepreg is
formulated for autoclave or press molding. An encapsulated sample rheometer (ESR) was used
to obtain its viscoelastic properties, including complex viscosity, gel time, and minimum
viscosity time, as well as glass transition temperature (Tg) and pressure window time for onestage
and two-stage cure cycles. A differential scanning calorimeter (DSC) was used to obtain
the degree of cure (DOC) for one-stage and two-stage cure cycles. The mechanical properties of
interest for specimens cured at one-stage cure cycles were short beam shear (SBS) strength,
combined loading compression (CLC) strength, CLC modulus, CLC Poisson’s ratio, open-hole
compression (OHC) strength, and OHC modulus. The SBS, CLC, and OHC tests were
performed at room temperature to obtain the mechanical properties.
For the one-stage cure cycles studied, it was observed that the mechanical properties,
except SBS strength, did not vary significantly; therefore, no correlation with the viscoelastic
properties or the DOC was found for them. Moreover, the failure mode for OHC specimens
cured at different one-stage cure cycles was similar. Likewise, the failure mode for CLC
specimens cured at different one-stage cure cycles was the same. However, the failure mode for
the least-cured SBS specimens was different from that of other SBS specimens. Also, the SBS
strength of the least-cured specimens was significantly less than that of other specimens. The
complex viscosity of the specimens cured at one-stage cure cycles in the ESR showed a similar
drop-off trend for the least-cured specimens. As such, SBS strength showed a good correlation
with the complex viscosity. SBS strength showed a weaker correlation with the Tg and DOC for
vii
the same cure cycles. The Tg had a strong correlation with the DOC for all one-stage cure cycles.
No correlation between gel time and other material properties was found. A considerable
improvement in SBS strength, final complex viscosity, Tg, and DOC of the least-cured
specimens was observed after the dwell time was increased enough to ensure that no further
curing occurred.
It was also observed that for the two-stage cure cycles, faster heat-up rates and higher
first-stage dwell temperatures resulted in faster curing.
The DOC for the entire cure cycle was modeled using the Springer-Loos cure kinetics
model for one-stage and two-stage cure cycles. The complex viscosity up to the gel time was
modeled using the Kenny viscosity model for one-stage and two-stage cure cycles. The modeling
results agreed well with the experimental data.
The results presented in this dissertation suggest that the ESR can be used as an ex-situ
cure-monitoring instrument to mimic autoclave/oven curing and, hence, eliminate the need for
multiple measurement instruments. The cure time-temperature data, provided by thermocouples
attached to the composite part in the autoclave/oven would be the only input to the rheometer for
cure monitoring. The complex viscosity as measured by the ESR was shown to be the best
viscoelastic property for monitoring the state of the material during cure for the following
reasons: (a) it could be precisely measured throughout the cure and post-cure cycles using the
rheometer, (b) it could reveal the important changes in the material state during cure, (c) it could
be modeled by sophisticated viscosity models, and (d) it could be correlated to the mechanical
properties of the composite material.
Utilizing the ESR as the main ex-situ cure-monitoring instrument makes it possible to
offer a new approach to curing composites. In this new approach, called Material State
Management (MSM), the acceptance of cured composite materials is based on the materials’
viscoelastic properties as measured by the ESR during cure and post-cure monitoring. Moreover,
knowledge of the material’s viscoelastic properties during cure can be used to improve the
current cure specifications. In the MSM approach, cure process confidence limits can be
prescribed based on the viscoelastic properties of the material, thus addressing the shortcomings
of the current time-temperature approach to curing.Thesis (Ph.D.)--Wichita State University, College of Engineering, Dept. of Mechanical Engineering
16
Alavi-Soltani, Seyed R. "Thermal, rheological, and mechanical properties of a polymer composite cured at staged cure cycles." Diss., Wichita State University, 2010. http://hdl.handle.net/10057/3289.
Full textAbstract:
Thermal, rheological, and mechanical properties of a polymer composite cured at
different one-stage and two-stage cure cycles were studied in this dissertation. A commercial
carbon-fiber prepreg, Cycom 977-2 UD, was used. This curing-toughened epoxy resin prepreg is
formulated for autoclave or press molding. An encapsulated sample rheometer (ESR) was used
to obtain its viscoelastic properties, including complex viscosity, gel time, and minimum
viscosity time, as well as glass transition temperature (Tg) and pressure window time for onestage
and two-stage cure cycles. A differential scanning calorimeter (DSC) was used to obtain
the degree of cure (DOC) for one-stage and two-stage cure cycles. The mechanical properties of
interest for specimens cured at one-stage cure cycles were short beam shear (SBS) strength,
combined loading compression (CLC) strength, CLC modulus, CLC Poisson’s ratio, open-hole
compression (OHC) strength, and OHC modulus. The SBS, CLC, and OHC tests were
performed at room temperature to obtain the mechanical properties.
For the one-stage cure cycles studied, it was observed that the mechanical properties,
except SBS strength, did not vary significantly; therefore, no correlation with the viscoelastic
properties or the DOC was found for them. Moreover, the failure mode for OHC specimens
cured at different one-stage cure cycles was similar. Likewise, the failure mode for CLC
specimens cured at different one-stage cure cycles was the same. However, the failure mode for
the least-cured SBS specimens was different from that of other SBS specimens. Also, the SBS
strength of the least-cured specimens was significantly less than that of other specimens. The
complex viscosity of the specimens cured at one-stage cure cycles in the ESR showed a similar
drop-off trend for the least-cured specimens. As such, SBS strength showed a good correlation
with the complex viscosity. SBS strength showed a weaker correlation with the Tg and DOC for
vii
the same cure cycles. The Tg had a strong correlation with the DOC for all one-stage cure cycles.
No correlation between gel time and other material properties was found. A considerable
improvement in SBS strength, final complex viscosity, Tg, and DOC of the least-cured
specimens was observed after the dwell time was increased enough to ensure that no further
curing occurred.
It was also observed that for the two-stage cure cycles, faster heat-up rates and higher
first-stage dwell temperatures resulted in faster curing.
The DOC for the entire cure cycle was modeled using the Springer-Loos cure kinetics
model for one-stage and two-stage cure cycles. The complex viscosity up to the gel time was
modeled using the Kenny viscosity model for one-stage and two-stage cure cycles. The modeling
results agreed well with the experimental data.
The results presented in this dissertation suggest that the ESR can be used as an ex-situ
cure-monitoring instrument to mimic autoclave/oven curing and, hence, eliminate the need for
multiple measurement instruments. The cure time-temperature data, provided by thermocouples
attached to the composite part in the autoclave/oven would be the only input to the rheometer for
cure monitoring. The complex viscosity as measured by the ESR was shown to be the best
viscoelastic property for monitoring the state of the material during cure for the following
reasons: (a) it could be precisely measured throughout the cure and post-cure cycles using the
rheometer, (b) it could reveal the important changes in the material state during cure, (c) it could
be modeled by sophisticated viscosity models, and (d) it could be correlated to the mechanical
properties of the composite material.
Utilizing the ESR as the main ex-situ cure-monitoring instrument makes it possible to
offer a new approach to curing composites. In this new approach, called Material State
Management (MSM), the acceptance of cured composite materials is based on the materials’
viscoelastic properties as measured by the ESR during cure and post-cure monitoring. Moreover,
knowledge of the material’s viscoelastic properties during cure can be used to improve the
current cure specifications. In the MSM approach, cure process confidence limits can be
prescribed based on the viscoelastic properties of the material, thus addressing the shortcomings
of the current time-temperature approach to curing.Thesis (Ph.D.)--Wichita State University, College of Engineering, Dept. of Mechanical Engineering
17
BELLUTO, Martina. "Prendersi cura. Un'analisi antropologica dei bisogni di salute nelle cure intermedie e di prossimità." Doctoral thesis, Università degli studi di Ferrara, 2021. http://hdl.handle.net/11392/2488243.
Full textAbstract:
L’esigenza di saper raccogliere i bisogni degli attori sociali e il loro mutamento è un tema all’ordine del giorno nel campo delle politiche sociali e sanitarie contemporanee, resosi ancora più evidente con l’avanzare della pandemia di Covid-19. Con l’insorgenza di bisogni di salute sempre più complessi legati all’aumento delle malattie croniche, delle disuguaglianze e delle trasformazioni che investono i rapporti sociali, i sistemi sanitari si trovano oggi ad affrontare un profondo processo di rinnovamento, che richiede di sviluppare sia strategie per far fronte all’imprevisto in termini di preparedness, quanto diversi modi di pensare, fare e costruire la cura.
Nell’ambito dei servizi sociali e territoriali, il personale medico-sanitario incontra una molteplicità di interazioni e informazioni che attraversano diversi campi di forza, in molte situazioni entrando in tensione con l’“istituito” della macchina amministrativa. In questo campo, la valutazione dei bisogni di salute dei pazienti chiama in causa una pluralità di professionisti che si muovono nella rete di cura e la sostanziano con un lavoro “vivo”, il quale difficilmente trova uno spazio di riconoscimento a livello istituzionale.
Sebbene il concetto di bisogno sia assunto come riferimento costante, sono rari i casi in cui questo tema venga esplorato in modo approfondito nelle sue dimensioni relazionali, pratiche e soggettive. All’interno della biomedicina, le molteplici dimensioni del bisogno tendono piuttosto a essere misurate e categorizzate per fini diagnostici. Una modalità diversa da come spesso questi sono vissuti, narrati e significati all’interno dell’esperienza di malattia, sia da parte dei pazienti che dei loro caregiver, operatori sociosanitari inclusi.
Attraverso un’analisi etnografica delle cure intermedie e di prossimità realizzata tra la Regione Emilia-Romagna e il Brasile, la ricerca intende offrire una riflessione antropologica dei bisogni di salute in quanto “fatti biografici e sociali”, con l’obiettivo di avanzare alcuni strumenti e proposte metodologiche riguardanti l’innovazione nei processi di lavoro nel campo dei servizi sociosanitari, in un’ottica centrata sulla dinamicità relazionale e collettiva delle pratiche di cura.
Nel testo sono trattati, in particolare, casi studio raccolti nel corso della collaborazione con le professioniste e i professionisti degli Ospedali di Comunità. Queste strutture, nate solo recentemente nel contesto italiano, sono dedicate alle cure intermedie, una forma di assistenza integrata tra l’ospedale e il domicilio, volta a coordinare al meglio azioni longitudinali di intervento sul territorio.The need to identify the needs of social actors and their change is a current topic in contemporary social and health policies, even reinforced by the spread of the Covid-19 pandemic. With the emergence of complex health needs related to chronic diseases, new inequalities, and the transformations of social relations, health systems face a renovation process that requires strategies to cope with preparedness and different ways of thinking, doing and building care. Health professionals deal with varying interactions and communications, often in tension with what is "established" by welfare administrations. In this field, assessing patients'health needs requires a plurality of professionals, who dynamically move in the network of care. Professionals substantiate it with living labour, rarely finding the space for it to be recognised at the institutional level. Although health policies made constant references to the concept of need, there are only a few cases in which this issue is explored in-depth in its relational, practical, and subjective dimensions. The multiple dimensions of need in the biomedical domain tend to be measured and categorised for diagnostic purposes, not converging with the way they are lived and experienced by patients and their caregivers – professional ones included. The research aims to offer an anthropological analysis of health needs as "biographical and social facts" through an ethnographic analysis of intermediate and proximity care between Emilia-Romagna and Brazil. It aims to observe and reflect on health needs as "biographical and social facts", advancing methodological tools and proposals for professionals based on a relational and collective approach to health. The case studies here observed deal in particular with Community Hospitals and their workers. These are structures for intermediate care, recently adopted in the Italian context, promoting integrated forms of health care, and providing coordinated and community-based interventions.
18
Mantovani, Alexandre. "A construção social da cura em cultos umbandistas: estudo de caso em um terreiro de umbanda da cidade de Ribeirão Preto - SP." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/59/59137/tde-05032007-174024/.
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Muitas pessoas se aproximam da umbanda procurando soluções para queixas que vão desde situações de saúde, problemas financeiros e de relacionamentos interpessoais. Como forma de tratamento os terreiros desempenham práticas específicas estruturadas seguindo a cosmologia umbandista, uma visão própria de mundo e de ser humano. No desempenho da cura tem-se uma situação em que o indivíduo é diagnosticado por uma \"semiologia espiritual\", uma leitura do mesmo a partir de elementos simbólicos religiosos. Este contexto abre espaço para uma pesquisa psicológica vinculada ao social, sendo para tanto necessária uma atitude de pesquisa não-reducionista e não- etnocêntrica. O objetivo desta pesquisa foi descrever e analisar práticas de cura desempenhadas em um terreiro de umbanda da cidade de Ribeirão Preto - SP, explorando possíveis sentidos enunciados nestas práticas.Trata-se de uma pesquisa qualitativa cujas estratégias de coleta de dados foram: observação-participante, anotações em diário de campo, entrevistas e registros audiovisuais. Os dados foram analisados com base na abordagem antropológica da pessoa, que preconiza o estudo do ser humano singular culturalmente contextualizado e distinto da representação da pessoa por um \"eu\" psicológico. Também toma-se como referência a psicanálise, principalmente pelo tratamento do sujeito feito por Lacan que se assemelha ao da antropologia e possibilita uma aproximação do psicológico ao social, uma vez que trata o sujeito estruturado por relações de alteridade em cadeias significantes, elementos simbólicos pertencentes ao universo cultural. Como resultados, verificou-se duas práticas de cura espiritual chamadas \"descarrego\" e \"transporte\". Para a análise agrupou-se dados referentes a oito situações observadas no campo em categorias que explicitam a compreensão umbandista sobre saúde e doença, as ações curativas e seus efeitos. Pôde-se observar que: o culto umbandista apresenta-se como uma cadeia significante formada por elementos verbais e não-verbais que enunciam diversos sentidos para comunidade do terreiro. Os sintomas da doença espiritual revelam o grau de proximidade do indivíduo com a religião. As práticas de cura apresentam uma estrutura de eficácia simbólica, tal como conceituada por Lévi-Strauss. Além disso, funcionam como forma de expressão de conflitos constituindo um \"drama social\" (Turner). O uso da psicanálise possibilitou uma aproximação entre o pesquisador e os colaboradores (umbandistas) e assim foi possível investigar as práticas de cura levando em conta a linguagem e os significados que estas apresentam para os mesmos. As práticas de cura apresentam uma função de inserção comunitária, pois na umbanda classificar um indivíduo como saudável ou doente implica em reconhecer seu grau de proximidade com a religião.Many people seek in umbanda solutions for their health problems, situations of interpersonal interactions and financial difficulties. The \"terreiros\" treat them by performances of specific practices based in a particular conception of the human being and a specific world view. The process of healing is carried out on the basis of a \"spiritual semeiology\" an interpretation based on symbolic religious elements. These conceptions and activities represents a good opportunity for a psychological and social researcher program, aimed to be non reductionist and also non ethnocentric. We describe the practices of cure performed in a \"terreiro\" of umbanda in the city of Ribeirão Preto - SP, looking for their possible significance. It is a qualitative investigation whose data were obtained by participant observations, daily field annotations, interviews and audiovisual registrations. The analysis based on the anthropologic approach of the person, aimed the singular human being in its cultural context, which differs from the mere representations of the person as a psychological \"ego\". The reference to psychoanalysis was useful specially through Lacan´s treatment of the self , which is akin to the anthropologic approach and makes possible an approximation of the psycho logic and the social, since it consider the person as psychologically structure by its relations with the symbolic elements of the cultural universe. We have studied two forms of spiritual cures which are called \"descarrego\" and \"transporte\". The data were clarified in eight categories according to the situations of observations in the field; these categories make explicit for the umbandists what is needed for the understanding of the wealth and disease states, the healing actions and their effects. We have shown that: the umbanda´s cult is characterized as a significant chain of verbal and non verbal elements that represents diverse meanings for the community; the symptoms of the spiritual disease reveal the degree of proximity of the persons to the religion; the practices of cure constitute a structure of \"symbolic effectiveness\", as in the sense given by Lévi-Strauss. Moreover, they functions as a form of expression of conflicts within the community, and thus constitute a \"social drama\" (Turner). The use of psychoanalysis permitted an approximation between the researcher and collaborators and made possible, in this way, to investigate the practices of cure taking in account the language and the significance that they represent for both of them. These practices have the function of an insertion in the community, since in the umbanda, the classification of a person as being healthy or sick implicate in the recognition of his/her degree of proximity to the religion.
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Rocha, Ricardo Ferreira da. "Defective models for cure rate modeling." Universidade Federal de São Carlos, 2016. https://repositorio.ufscar.br/handle/ufscar/7751.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Modeling of a cure fraction, also known as long-term survivors, is a part of survival analysis. It studies cases where supposedly there are observations not susceptible to the event of interest. Such cases require special theoretical treatment, in a way that the modeling assumes the existence of such observations. We need to use some strategy to make the survival function converge to a value p 2 (0; 1), representing the cure rate. A way to model cure rates is to use defective distributions. These distributions are characterized by having probability density functions which integrate to values less than one when the domain of some of their parameters is di erent from that usually de ned. There is not so much literature about these distributions. There are at least two distributions in the literature that can be used for defective modeling: the Gompertz and inverse Gaussian distribution. The defective models have the advantage of not need the assumption of the presence of immune individuals in the data set. In order to use the defective distributions theory in a competitive way, we need a larger variety of these distributions. Therefore, the main objective of this work is to increase the number of defective distributions that can be used in the cure rate modeling. We investigate how to extend baseline models using some family of distributions. In addition, we derive a property of the Marshall-Olkin family of distributions that allows one to generate new defective models.
A modelagem da fração de cura e uma parte importante da an álise de sobrevivência. Essa área estuda os casos em que, supostamente, existem observa ções não suscetíveis ao evento de interesse. Tais casos requerem um tratamento teórico especial, de forma que a modelagem pressuponha a existência de tais observações. E necessário usar alguma estratégia para tornar a função de sobrevivência convergente para um valor p 2 (0; 1), que represente a taxa de cura. Uma forma de modelar tais frações e por meio de distribui ções defeituosas. Essas distribuições são caracterizadas por possuirem funções de densidade de probabilidade que integram em valores inferiores a um quando o domínio de alguns dos seus parâmetros e diferente daquele em que e usualmente definido. Existem, pelo menos, duas distribuições defeituosas na literatura: a Gompertz e a inversa Gaussiana. Os modelos defeituosos têm a vantagem de não precisar pressupor a presença de indivíduos imunes no conjunto de dados. Para utilizar a teoria de d istribuições defeituosas de forma competitiva e necessário uma maior variedade dessas distribuições. Portanto, o principal objetivo deste trabalho e aumentar o n úmero de distribuições defeituosas que podem ser utilizadas na modelagem de frações de curas. Nós investigamos como estender os modelos defeituosos básicos utilizando certas famílias de distribuições. Além disso, derivamos uma propriedade da famí lia Marshall-Olkin de distribuições que permite gerar uma nova classe de modelos defeituosos.
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Li, Li. "Adhesion and cure kinetics of photopolymers." Thesis, Connect to Dissertations & Theses @ Tufts University, 1999. http://catalog.hathitrust.org/api/volumes/oclc/48224834.html.
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Thesis (Ph.D.)--Tufts University, 1999.Submitted to the Dept. of Mechanical Engineering. Includes bibliographical references (leaves 110-113). Access restricted to members of the Tufts University community. Also available via the World Wide Web;
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Singh, Ashki. "The talking cure in the 'tropics'." Thesis, Queen Mary, University of London, 2018. http://qmro.qmul.ac.uk/xmlui/handle/123456789/33941.
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This dissertation examines psychoanalysis in a colonial context, tracing its history in early to mid-twentieth century India. A rich, neglected archive of diaries, letters, administrative documents, as well as psychoanalytical and literary writing in Bengali and English, are drawn on to offer an account of the Indian Psychoanalytical Society (est. 1921), and the anthropologists, doctors, army officers and political figures who were in different ways intimately involved with psychoanalysis. Reconstructing these narratives, and by means of a close reading of texts by Freud, I suggest that the understandings of temporality, sexuality and authority in Freudian psychoanalysis resist colonial discourses of progress and civilisation, notably in relation to the category of the 'primitive', thus frustrating attempts to appropriate the theory for colonial endeavours. In this thesis, psychoanalysis is both an object of historical study, and a form of questioning, part of colonial history and a body of writing and theory available for contested readings. I discuss writing by two colonial psychoanalysts, Lt. Colonel Claud Daly, and Owen A.R. Berkeley Hill, which combines an investment in psychoanalysis with commitment to Empire, based on a desire for all-knowing psychic and political mastery. In contrast, the memoirs of renowned psychoanalyst Wilfred Bion, recounting his childhood in India, are read for their more complex psychic register and anti-colonial strain. Records left by dream-collecting colonial administrators in the Naga Hills, and documents relating to the trial and 'insanity plea' of revolutionary nationalist Gopinath Saha, show us the historical operations of psychoanalysis in collective life. In addition, literary writing by the modernist poet H.D., Temsula Ao, Bankimcandra Chatterji, and Rabindranath Tagore, offers another template for examining the issues raised by both the historical and psychoanalytical writing.
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Ogilvie, Megan Jacqueline 1979. "Ocean fertilization : ecological cure or calamity." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/39431.
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Thesis (S.M. in Science Writing)--Massachusetts Institute of Technology, Dept. of Humanities, Program in Writing and Humanistic Studies, 2004.Vita.
Includes bibliographical references (leaves 35-41).
The late John Martin demonstrated the paramount importance of iron for microscopic plant growth in large areas of the world's oceans. Iron, he hypothesized, was the nutrient that limited green life in seawater. Over twenty years later, Martin's iron hypothesis is widely considered to be the major contribution to oceanography in the second half of the 20th century. Originating as an ecosystem experiment to test Martin's iron hypothesis, iron fertilization experiments are now used as powerful tools to study the world's oceans. Some oceanographers are concerned that these experiments are catapulting ocean science into a new era. The vast stretches of ocean play a key role in the global carbon cycle, and thus in regulating Earth's climate. Some scientists, engineers and international policy makers claim that dissolving iron in the ocean will help stop global warming. Adding large amounts of iron to the oceans may drastically increase the amount of carbon dioxide that phytoplankton can capture from the atmosphere, thereby reducing the most common greenhouse gas. But intentional iron fertilization over great expanses of the ocean may have unintended consequences for the world's largest ecosystem. The open ocean is one of the planet's last frontiers and a part of the global commons. As such, using the open ocean as a means to solve the complex problem of global warming raises deep questions about how humans think of and use the Earth. The question remains: Should humans use the ocean as a means to regulate a changing climate?
by Megan Jacqueline Ogilvie.
S.M.in Science Writing
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Toffey, Ackah. "Cure studies of network-forming polyurethanes." Thesis, Virginia Tech, 1993. http://hdl.handle.net/10919/41509.
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The polyhydroxy character of lignocellulosics and their natural abundance make them good candidates for the manufacture of polyurethanes.
The cure characteristics of hydroxypropyl-cellulose and hydroxypropyl lignin (HPC and HPL, respectively) with polymeric methylene diphenyl diisocyanate (MDI) was studied via dynamic mechanical thermal analysis (DMTA).
HPC/MDI and HPL/MDI resins flow at 30°C and proceed to cure at 50°C. The latter has excellent thermal stability over the former. Crosslinking of HPL and HPC with MDI follow an nth order kinetics, with an order of reaction of 2 and an apparent activation energy in the range of 12.9 kcal/mol - 14.7 kcal/mol.
The rate of cure with time is higher in HPL-based polymers than HPC-based ones at the initial stage of cure; the difference vanishes at later stages. This demonstrates that the hydroxyl groups in HPC are less accessible to the NCO groups, and that cure rate might be dependent on diffusion limitations at later stages.
Degree of cure, under all cure schedules, follows a parallel trend, and has to do with the fact that the hydroxyl groups of HPC are less accessible to isocyanate. Both HPL and HPC react with MDI at a reduced rate in comparison to a synthetic polyol: caprolactone triol.
Time-glass transition temperature superposition was used to calculate times to vitrification of the HPL-based polymers, and is presented in a TTT cure diagram. This bio-based polymer displays the s-shaped vitrification pattern characteristics of thermosets. A similar approach did not work with HPC-based polymers. HPC- and HPL-based polymers did not display damping transitions, in isothermal cure, typical of gelation and vitrification. As the isocyanate to hydroxyl ratio (NCO:OH) increased, the glass transition temperature of the polymers increased, and the transition amplitude and width decreased and increased, respectively.
In practical terms, this study illustrates that it is advantageous to use
a) to use high isocyanate to hydroxyl ratios in order to produce polyurethanes which retain desirable damping behavior over a wider range of temperature.
b) to use HPC/MDI resins in those situations where retention of stiffness at temperatures below 230° is required.
c) to use HPL where rapid cure is desired.
The study also reveals that the relative reactivity of water, HPL and HPC with isocyanate takes the form water > HPL > HPC.Master of Science
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Schmiegelow, Margaret Leigh. "A Double Pain, A Double Cure." The Ohio State University, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu1618988485414121.
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Harouni, Moussa. "Cure psychiatrique et ses prolongements therapeutiques." Paris 8, 1987. http://www.theses.fr/1987PA080078.
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La prise en charge en psychiatrie, est un theme qui ne cesse de deferler la chronique depuis plusieurs annees et cela depuis la seconde guerre mondiale a travers le monde et plus particulierement dans le monde occidental. En france, l'institution psychiatrique est en voie de transition pour eventuellement aboutir a un changement, ouvrant la voie a une prise en charge differente remettant en cause l'institution totalitaire et s'ouvrant d'avantage et reellement a une politique de secteur, qui se rapproche d'une certaine facon des differentes theses des mouvements dits en alternative a la psychiatrie. Ainsi, dans cette these, la prise en charge dans une institution psychiatrique (c. H. S. ) de maison-blanche (secteur de paris) est analysee a travers des interviews, des observations, des exposes de cas etc. . . . L'analyse institutionnelle est faite afin de demontrer l'insuffisance de la prise en charge en psychiatrie. De ce fait une etude concernant les institutions en alternative a la psychiatrie institutionnelle (etats-unis, angleterre, italie, france), nous a permis d'etablir un bilan comparatif, qui nous a aide a mettre en place de nouvelles strategies pour une meilleure prise en charge.
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Angueli, Daniella. "Les résistances dans la cure psychanalytique." Rennes 2, 2010. http://www.theses.fr/2010REN20007.
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Le terme de résistance, outre sa signification courante simple, fut utilisé essentiellement comme transition conceptuel et mot de passe pour exprimer toute ambiguïté, tout obstacle ou toute marche arrière dans la pratique des analystes de plus ou moins toutes les tendances théoriques. Pour notre travail, nous avons suivi l’itinéraire des résistances depuis l’époque où le terme était quasi indispensable dans les théorisations des premiers analystes jusqu’à l’époque contemporaine où il a été assez négligé. En suivant pas à pas l’élaboration théorique des analystes qui se sont occupés du sujet et en essayant d’opérer une classification sommaire sur la base de leur école et de la formation qu’elle leur avait dispensée, nous nous sommes efforcée de voir quel contenu donnait chacun d’entre eux au terme résistance, quelles étaient les éventuelles influences qu’ils avaient subies et les solutions qu’ils proposaient. Nous avons vu à quels autres termes/constructions théoriques ils ont relié les résistances dans le but de les expliquer, d’y faire face ou de les éviter et à travers quels courants implicites ou explicites ils ont influencé leurs collègues de par le monde. En quoi l’utilisation du terme les a-t-il aidés et pour quelles raisons l’ont-ils peu à peu abandonnée ? Notre voyage, qui ne s’est pas limité à un côté de l’Atlantique, nous a montré que, finalement, les circonstances géographiques, sociales et politiques avaient influencé leurs choix mais ne suffisaient pas à expliquer un résultat qui était le même pour toutes les sociétés psychanalytiques : le terme a été abandonné en même temps que d’autres éléments très importants de la technique psychanalytiqueThe resistances, an ever-present notion in the works written by Freud and the first analysts around him, are as old as psychoanalysis itself. Beyond its usual simplified sense, the term was essentially used as a conceptual passageway and password which expressed any ambiguity, any obstacle or any regression in the practice of the analysts from most theoretical trends. In this research, we followed the evolution of the resistances from the time the term was unavoidable, in the first analysts´s theorizations, until today where it has been discarded. Following step by step the theoretical approaches of the analysts, who dealt with the issue, and attempting a basic classification according to the formation they had acquired in the psychoanalytic school they belonged, we tried to specify the content that each of them gave to the term, under which possible influences they worked and which solutions they proposed. We clarified which other terms/theoretical constructions they related the resistances with, in order to explain, confront or avoid them, and through which implicit or explicit trends they influenced their colleagues across the world. To what extend did the use of the term help them and why did they gradually discard it ? Our journey, which was not restricted to only one side of the Atlantic Ocean, showed that geographical, social and cultural conditions have influenced their choices. However, they are not sufficient to explain the end result, regarding resistances, which was the same in all the psychoanalytical societies despite of the different course that they followed: the term was discarded – along with other very important elements of the psychoanalytical technique
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Kleemeyer, Maike. "Exercise - A Cerebral Anti-aging Cure?" Doctoral thesis, Humboldt-Universität zu Berlin, 2018. http://dx.doi.org/10.18452/18749.
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Fortschreitendes Alter geht häufig mit Leistungsabnahmen in kognitiven Aufgaben einher. Eine steigende Anzahl Studien zeigt, dass regelmäßige körperliche Aktivität negativen Alterseffekten entgegenwirken kann und somit zur Erhaltung kognitiver und zerebraler Funktionen im Alter beiträgt. Die vorliegende Dissertation untersuchte im Rahmen eines Ausdauertrainings die Zusammenhänge zwischen Veränderungen in der körperlichen Fitness und Veränderungen in Gehirn und Verhalten bei älteren Erwachsenen. Studie I zeigt, dass zuvor gefundene Vergrößerungen des Hippocampus auf Änderungen der Mikrostruktur des zugrundeliegenden Gewebes zurückgeführt werden können. Die Probanden, die ihre Fitness am meisten verbesserten, zeigten auch die stärkste Verdichtung des Hippocampusgewebes. Die Verdichtung des Gewebes stand wiederum in positivem Zusammenhang mit der Veränderung im Hippocampusvolumen. Diese Ergebnisse weisen darauf hin, dass Veränderungen im Volumen aus einer Vermehrung der Zellmembranen resultieren und nicht aus der Ausdehnung bereits vorhandener Zellen. In Studie II hingen Veränderungen in
der Fitness zusammen mit Veränderungen in der Mikrostruktur eines präfrontalen Traktes der weißen Substanz, nämlich dem Forceps minor. Gleichermaßen hingen die Veränderungen in der Mikrostruktur des Forceps minor mit Veränderungen in einem
zusammengesetzten Maß fluider kognitiver Fähigkeiten zusammen. Dieses Ergebnis zeigt, dass Veränderungen in der Mikrostruktur der weißen Substanz möglicherweise zu den positiven Auswirkungen von körperlicher Aktivität auf kognitive Fähigkeiten beitragen. Studie III zeigt, dass Veränderungen der Fitness positiv mit Veränderungen der neuronalen Spezifität korrelieren, welches als indirektes Maß für dopaminerge Neuromodulation angenommen wird. Zusammenfassend erweitern die Ergebnisse dieser Dissertation die Literatur über positive Effekte von körperlicher Aktivität auf Alterungsprozesse und stärken den Kenntnisstand über zugrundeliegende Mechanismen.Advanced age has been consistently linked to performance deterioration in cognitive tasks targeting the ability to mentally manipulate information. A growing body of literature suggests that regular physical exercise alleviates the adverse effects of age and helps to preserve cognitive and cerebral capacities in old age. The present dissertation investigated associations between changes in fitness and changes in cerebral and cognitive measures within a group of older adults who participated in an exercise intervention. Paper I shows that previously reported increases in hippocampal volume can be linked to exercise-induced changes in the underlying tissue microstructure. The participants who improved most in fitness showed most increments in hippocampal tissue density. Changes in tissue density were in turn positively associated with changes in hippocampal volume. This finding suggests that volumetric changes result from an increase in the bulk of cell membranes, and not from a mere dilation of existing cells. In Paper II, changes in fitness were associated with changes in the microstructure of a prefrontal white matter tract, namely the forceps minor. Likewise, changes in forceps minor microstructure were related to changes in a composite score of fluid cognitive abilities. This result indicates that changes in white matter microstructure may contribute to the beneficial effects of exercise on cognition. Paper III demonstrates that changes in fitness are positively correlated with changes in neural specificity, presumably an indirect marker of dopaminergic neuromodulation. In summary, findings from the present dissertation extend the literature on beneficial effects of exercise on age-related deterioration and add knowledge regarding the underlying mechanisms.
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Lesimple, Sophie. "Une cure thermale à Avène : Santé et beauté." Aix-Marseille 2, 1993. http://www.theses.fr/1993AIX22620.
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GRIFO, PAOLA. "Cure al limite, limite delle cure: opinioni "ingenue" ed "esperte" rispetto alle cure di fine vita, effetti di burnout. Confronto fra operatori sanitari lombardi e popolazione comune." Doctoral thesis, Università Cattolica del Sacro Cuore, 2008. http://hdl.handle.net/10280/233.
Full textAbstract:
Parlare di morte è un tabù della nostra società. L'incremento quantitativo di pazienti terminali impone peraltro uno sforzo per il miglioramento della loro qualità di vita. Lo psicologo deve comprendere la domanda sociale su questi temi, per costruire un adeguato intervento clinico-formativo rivolto agli operatori sanitari. Obiettivi della ricerca sono di individuare: la rappresentazione di disponibilità di Cure Palliative (CP); gli atteggiamenti degli operatori sanitari e del pubblico circa le diverse opzioni di fine vita (End-Of-Life, EOL), verificando l'ipotesi che i sanitari e in particolare i palliativisti siano meno favorevoli all'eutanasia e più alle CP; i predittori delle opinioni; l'influenza delle difficoltà concettuali sulla stabilità delle opinioni; il rapporto tra le opinioni e la rappresentazione delle CP; le diverse percezioni dei bisogni del paziente terminale; il burnout dei palliativisti rispetto agli altri sanitari. 524 soggetti (265 sanitari, di cui 118 palliativisti; 259 non-sanitari) hanno compilato un questionario self-report, sviluppato ad-hoc. Ai 265 sanitari è stato inoltre somministrato il Maslach Burnout Inventory. I non-sanitari risultano più favorevoli all'eutanasia e meno alle CP rispetto ai sanitari. Analisi lineari indicano, fra i predittori dell'accordo all'eutanasia, religiosità e lavoro sanitario; le opinioni risultano peraltro instabili. Il campione presenta livelli di burnout significativamente inferiori alla media italiana; i palliativisti segnalano un burnout minore dei colleghi nella dimensione EE; il sostegno alla relazione costituisce elemento protettivo. L'incidenza di fattori non misurabili indica l'opportunità di approfondimenti qualitativo-idiografici. Lo studio suggerisce la necessità di una maggiore conoscenza delle tematiche EOL. Lo psicologo deve sostenere presso i caregiver un luogo simbolico per l'elaborazione dell'evento-morte.In our society death is a taboo topic. The increase of dying patients calls for an improvement in their quality of life. Psychologists need to understand the social demand on these issues, in order to promote appropriate clinical and training interventions for health workers. In this research we looked at the representation of availability of Palliative Care (PC) as well as attitudes of health workers and the general public towards different End-Of-Life (EOL) options. We tested the hypothesis that health workers and especially palliative care workers disagree with euthanasia and agree with PC more than the public. We also investigated attitudes predictors; the influence of conceptual difficulties on attitudes stability; the relationship between attitudes on euthanasia and PC representation; different perceptions of dying patients' needs; palliative care and other health workers' burnout. 524 subjects (265 health workers: 118 involved in palliative cares and 147 in other health sectors; 259 from the general public) filled in a self-report questionnaire, created ad-hoc. The 265 health workers also filled in the Maslach Burnout Inventory. The public, compared to health workers, agreed more with euthanasia and less with PC. Linear analysis indicates that religious beliefs and health work are the only significant predictors of this agreement, even if attitudes are quite unstable. The burnout levels in our sample are significantly lower than Italian mean levels. Palliative care workers show lower levels in EE subscale than their colleagues; supporting relationships are a protective factor. The incidence of non-measurable factors suggests the opportunity of further qualitative studies. This research highlights the need for deeper knowledge of EOL issues. Psychologists should give to all professional carers the opportunity for reflective practice and symbolic work on the event of dying.
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GRIFO, PAOLA. "Cure al limite, limite delle cure: opinioni "ingenue" ed "esperte" rispetto alle cure di fine vita, effetti di burnout. Confronto fra operatori sanitari lombardi e popolazione comune." Doctoral thesis, Università Cattolica del Sacro Cuore, 2008. http://hdl.handle.net/10280/233.
Full textAbstract:
Parlare di morte è un tabù della nostra società. L'incremento quantitativo di pazienti terminali impone peraltro uno sforzo per il miglioramento della loro qualità di vita. Lo psicologo deve comprendere la domanda sociale su questi temi, per costruire un adeguato intervento clinico-formativo rivolto agli operatori sanitari. Obiettivi della ricerca sono di individuare: la rappresentazione di disponibilità di Cure Palliative (CP); gli atteggiamenti degli operatori sanitari e del pubblico circa le diverse opzioni di fine vita (End-Of-Life, EOL), verificando l'ipotesi che i sanitari e in particolare i palliativisti siano meno favorevoli all'eutanasia e più alle CP; i predittori delle opinioni; l'influenza delle difficoltà concettuali sulla stabilità delle opinioni; il rapporto tra le opinioni e la rappresentazione delle CP; le diverse percezioni dei bisogni del paziente terminale; il burnout dei palliativisti rispetto agli altri sanitari. 524 soggetti (265 sanitari, di cui 118 palliativisti; 259 non-sanitari) hanno compilato un questionario self-report, sviluppato ad-hoc. Ai 265 sanitari è stato inoltre somministrato il Maslach Burnout Inventory. I non-sanitari risultano più favorevoli all'eutanasia e meno alle CP rispetto ai sanitari. Analisi lineari indicano, fra i predittori dell'accordo all'eutanasia, religiosità e lavoro sanitario; le opinioni risultano peraltro instabili. Il campione presenta livelli di burnout significativamente inferiori alla media italiana; i palliativisti segnalano un burnout minore dei colleghi nella dimensione EE; il sostegno alla relazione costituisce elemento protettivo. L'incidenza di fattori non misurabili indica l'opportunità di approfondimenti qualitativo-idiografici. Lo studio suggerisce la necessità di una maggiore conoscenza delle tematiche EOL. Lo psicologo deve sostenere presso i caregiver un luogo simbolico per l'elaborazione dell'evento-morte.In our society death is a taboo topic. The increase of dying patients calls for an improvement in their quality of life. Psychologists need to understand the social demand on these issues, in order to promote appropriate clinical and training interventions for health workers. In this research we looked at the representation of availability of Palliative Care (PC) as well as attitudes of health workers and the general public towards different End-Of-Life (EOL) options. We tested the hypothesis that health workers and especially palliative care workers disagree with euthanasia and agree with PC more than the public. We also investigated attitudes predictors; the influence of conceptual difficulties on attitudes stability; the relationship between attitudes on euthanasia and PC representation; different perceptions of dying patients' needs; palliative care and other health workers' burnout. 524 subjects (265 health workers: 118 involved in palliative cares and 147 in other health sectors; 259 from the general public) filled in a self-report questionnaire, created ad-hoc. The 265 health workers also filled in the Maslach Burnout Inventory. The public, compared to health workers, agreed more with euthanasia and less with PC. Linear analysis indicates that religious beliefs and health work are the only significant predictors of this agreement, even if attitudes are quite unstable. The burnout levels in our sample are significantly lower than Italian mean levels. Palliative care workers show lower levels in EE subscale than their colleagues; supporting relationships are a protective factor. The incidence of non-measurable factors suggests the opportunity of further qualitative studies. This research highlights the need for deeper knowledge of EOL issues. Psychologists should give to all professional carers the opportunity for reflective practice and symbolic work on the event of dying.
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Cody, Michael. "Dialogic regulation : the talking cure for corporations." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/48452.
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The corporations of our future will be whatever we can collectively imagine and work together to make a reality. Dialogic law and regulation is a generative tool that can build the bridge between the present and an imagined future. Regulators keep people on the bridge by identifying the kinds of dialogues we want corporate actors to have and by encouraging, coaching, and sometimes assisting them to have those dialogues. This approach works because small changes in the way corporate actors talk to and interact with each other can have dramatic effects on the emergent corporate culture.
This thesis develops and tests a theory of Dialogic Regulation. The theory assumes that corporate law and regulation is about attaining or maintaining a desired corporate behaviour, the best way to change behaviour is to learn a new one, and learning is a social process that involves dialogue. The model was tested using an experimental game where the rules of the game were treated as proxies for the “law” and the authority figure directing the experiment was treated as a proxy for the corporate “regulator”. The game was called the “Pay-Off” game. Half-way through the game the rules were changed using one of three different regulatory techniques: 1) Rules: a simple rule change, 2) Audit: a rule change combined with an audit and punishment procedure for infractions, and 3) Dialogic: a rule change combined with a dialogic intervention about the rules. Participants were tested not only for their behavioural reactions to the interventions (Compliance to the rules) but also to determine if they learned anything about the rules (Adherence to the rules).
The games experiment showed that for simply behavioural outcomes the Audit Based
Regulation approach was the most effective. The experiment also showed that there is significant
promise in a Dialogic Regulation approach if the regulatory desire is to have participants learn. While Dialogic Regulation shows promise, a lot more work needs to be done to refine the application of the theory before it is used in real-life regulatory settings.Law, Faculty of
Graduate
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Wang, Jinwu. "Cure kinetics of wood phenol-formaldehyde systems." Online access for everyone, 2007. http://www.dissertations.wsu.edu/Dissertations/Spring2007/j_wang_042207.pdf.
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Wang, Lu. "Cure Rate Model with Spline Estimated Components." Diss., Virginia Tech, 2010. http://hdl.handle.net/10919/28359.
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In some survival analysis of medical studies, there are often long term survivors who can be considered as permanently cured. The goals in these studies are to estimate the cure probability of the whole population and the hazard rate of the noncured subpopulation. The existing methods for cure rate models have been limited to parametric and semiparametric models. More specifically, the hazard function part is estimated by parametric or semiparametric model where the effect of covariate takes a parametric form. And the cure rate part is often estimated by a parametric logistic regression model. We introduce a non-parametric model employing smoothing splines. It provides non-parametric smooth estimates for both hazard function and cure rate. By introducing a latent cure status variable, we implement the method using a smooth EM algorithm. Louisâ formula for covariance estimation in an EM algorithm is generalized to yield point-wise confidence intervals for both functions. A simple model selection procedure based on the Kullback-Leibler geometry is derived for the proposed cure rate model. Numerical studies demonstrate excellent performance of the proposed method in estimation, inference and model selection. The application of the method is illustrated by the analysis of a melanoma study.Ph. D.
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Scott, Brian Cameron. "Evaluation of Phenol Formaldehyde Resin Cure Rate." Thesis, Virginia Tech, 2005. http://hdl.handle.net/10919/33222.
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Cure time is often the bottleneck of composite manufacturing processes, therefore it is important to understand the cure of todayâ s thermosetting adhesives. This research attempts to characterize the cure rate of two commercial phenol-formaldehyde adhesives. Two methods are used, parallel-plate rheometry and dielectric spectroscopy. Viscosity data from a parallel-plate rheometer may be used to track the advance of polymerization as a function of temperature. This data can then be used to optimize press conditions and reduce production times and costs.
The research will further examine resin cure through dielectric analysis; such a technique could monitor resin cure directly and in real-time press situations. Hot-pressing processes could conceivably no longer require a set press schedule; instead they would be individually set based on dielectric data for every press batch. Such a system may lead to a more efficient and uniform product because press times could be based on individual press cycles instead of entire product lines. A more likely scenario, however, is the use of in situ adhesive cure monitoring for troubleshooting or press schedule development.
This research characterized the cure of two phenol-formaldehyde resins using parallel-plate rheometry, fringe-field dielectric analysis, and parallel-plate dielectric analysis. The general shape of the storage modulus vs. time curve and the gel and vitrification points in a temperature ramp were found.
Both dielectric analysis techniques were able to characterize trends in the resin cure and detect points such as vitrification. The two techniques were also found to be comparable when the cure profiles of similar conditions were examined.
Master of Science
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Ganoe, Kristy L. "Mindful Movement as a Cure for Colonialism." Bowling Green State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1367936488.
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MASSIANI, MARIE-PAULE. "Prolapsus perineaux : classification et cure chirurgicale systematisee." Aix-Marseille 2, 1993. http://www.theses.fr/1993AIX20094.
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TANZI, Silvia. "Cure Palliative Precoci nei pazienti onco ematologici." Doctoral thesis, Università degli studi di Modena e Reggio Emilia, 2021. http://hdl.handle.net/11380/1246164.
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Le cure palliative precoci insieme alle cure ematologiche standard per questo tipo di pazienti sono ritenute necessarie in tutto il mondo, ma poco si sa circa l’efficacia della loro integrazione.
È stata eseguita una revisione sistematica della letteratura per sintetizzare le prove di efficacia sull'impatto delle cure palliative precoci sulla qualità della vita e sull'uso delle risorse dei malati di cancro ematologico.
I termini di ricerca erano cure palliative precoci o cure simultanee o integrate o concomitanti e pazienti ematologici o oncoematologici. Sono stati esaminati un totale di 296 studi. Otto articoli sono stati inclusi nella sintesi dei risultati, due studi controllati hanno fornito dati sull'efficacia degli interventi di cure palliative e 6 studi non comparativi sono stati inclusi. Poiché non è stato possibile realizzare una meta analisi, è stata eseguita una sintesi narrativa dei risultati dello studio.
Gli studi sulle cure palliative precoci e sui pazienti con cancro ematologico sono scarsi e non sono stati realizzati in modo prospettico.
La revisione sistematica è stata registrata su PROSPERO e pubblicata in Ottobre 2020
A seguire abbiamo scritto un protocollo di ricerca per uno studio randomizzato sulle cure palliative precoci e i malati di cancro ematologico: abbiamo sviluppato un intervento di cure palliative integrato con le cure ematologiche standard. L'obiettivo del protocollo è l'esplorazione della fattibilità dell'intervento integrato dal punto di vista dei pazienti, dei professionisti e dei caregiver e sulla valutazione preliminare della sua efficacia.Lo studio prevede che un servizio specialistico di cure palliative segua mensilmente ogni paziente ambulatoriale o in regime consulenziale durante qualsiasi ricovero ospedaliero. I palliativisti e gli ematologi discutono dei problemi dei pazienti per assicurare un approccio integrato alla cura del paziente.
La parte quantitativa dello studio è monocentrico di superiorità a gruppi paralleli con randomizzazione bilanciata che confronta l’intervento di cure palliative sperimentale più la cura standard ematologica rispetto alla sola cura standard ematologica.
L'end-point primario verrà calcolato sull'aderenza all’intervento di cure palliative cosí come pianificato, misurato come la percentuale di pazienti randomizzati al braccio sperimentale che partecipano a tutte le visite di cure palliative pianificate nelle 24 settimane successive alla randomizzazione.
Il protocollo del trial è stato registrato su ClinicalTrials.gov: NCT03743480 e pubblicato nel 2020
Abbiamo avviato il trial nel novembre 2018, tuttavia l'arruolamento a questo protocollo si è dimostrato lento e difficile; da quando è iniziato sono stati arruolati 13 pazienti coi loro caregiver.
Abbiamo quindi deciso di approfondire questa difficoltà insieme ad altri Specialisti internazionali del settore realizzando una intervista/survey. Lo scopo dell'indagine sarà quello di fornire una panoramica delle difficoltà nell'arruolamento dei pazienti in cure palliative specificamente indirizzate alle neoplasie ematologiche esplorando l’opinione degli esperti ed elaborare cosí una teoria dell'arruolamento di ispirazione realista, raccogliendo dati dalla nostra indagine e dalla letteratura rivista.
I risultati di questo studio verranno mostrati durante la discussione della tesiDuring my PhD I’ve explored the integration between palliative care and hematologic cancer patient. Early palliative care together with standard haematologic care for advanced patients is needed worldwide but little is known about its effect. I first performed a systematic literature review to synthesize the evidence on the impact of early palliative care on haematologic cancer patients’ quality of life and resource use. The search terms were early palliative care or simultaneous or integrated or concurrent care and haematologic or onco-haematologic patients. The following databases were searched: PubMed, Embase, Cochrane, CINHAL, and Scopus. Additional studies were identified through cross-checking the reference articles. Studies were in the English language, with no restriction for years. Two researchers independently reviewed the titles and abstracts, and one author assessed full articles for eligibility. A total of 296 studies titles were reviewed. Eight articles were included in the synthesis of the results, two controlled studies provided data on the comparative efficacy of PC interventions, and six one-arm studies were included. Since data pooling and meta-analysis were not possible, only a narrative synthesis of the study results was performed. The quality of the two included comparative studies was low overall. The quality of the 6 non-comparative studies was high overall, without the possibility of linking the observed results to the implemented interventions. Studies on early palliative care and cancer patients are scarce and have not been prospectively designed. More research on the specific population target, type and timing of palliative care intervention and standardization of collected outcomes is required. The systematic review was registered on PROSPERO and published in October 2020 (Tanzi Silvia, Venturelli Francesco, Luminari Stefano, Merlo Franco Domenico, Braglia Luca, Bassi Chiara, Costantini Massimo. Early palliative care in haematological patients: a systematic literature review. BMJ Support Palliat Care) I consequently wrote a research protocol for an RCT on Early Palliative Care and Haematologic Cancer Patients: we developed a palliative care intervention (PCI) integrated with standard hematological care. The aim of the protocol was focused on exploring the feasibility of the intervention by patients, professionals, and caregivers and on assessing its preliminary efficacy. It was a mixed-methods phase 2 trial. The Specialist Palliative Care Team (SPCT) follow each patient on a monthly basis in the outpatient clinic or will provide consultations during any hospital admission. SPCT and hematologists discuss active patient issues to assure a team approach to the patient’s care. This quantitative study is a monocentric parallel-group superiority trial with balanced randomization comparing the experimental PCI plus hematological standard care versus hematological standard care alone. The primary endpoint will calculate on adherence to the planned PCI, measured as the percentage of patients randomized to the experimental arm who attend all the planned palliative care visits in the 24 weeks after randomization. The qualitative study follows the methodological indications of concurrent nested design and was aimed at exploring the acceptability of the PCI from the point of view of patients, caregivers, and physicians. The trial was registered on ClinicalTrials.gov: NCT03743480 and Published in 2020 (Tanzi Silvia, Luminari Stefano, Cavuto Silvio, Turola Elena, Ghirotto Luca, Costantini Massimo. Early palliative care versus standard care in hematologic cancer patients at their last active treatment: study protocol of a feasibility trial.BMC Palliat Care. 2020;19(1):53) We started the RCT in November 2018: in this trial, we will test the feasibility of an integrated palliative care approach starting when the hematologists to propose the last active treatment
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Кубатко, Олександр Васильович, Александр Васильевич Кубатко, Oleksandr Vasylovych Kubatko, and Oleksandra Nilova. "Is economic growth a cause or cure for the environmental degradation: the case of environmental kuznets curve." Thesis, Видавництво СумДУ, 2008. http://essuir.sumdu.edu.ua/handle/123456789/8201.
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Lucchese, Maria Cecilia. "Curam-se cidades uma proposta urbanística da década de 70." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/16/16131/tde-05112013-110903/.
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Este trabalho trata do Programa Cura, proposta urbanística desenvolvida pelo Arquiteto carioca Harry James Cole em 1972, que visava propiciar a qualificação de bairros claramente delimitados, através da implantação de redes de infra-estrutura, equipamentos públicos - escolas, creches, hospitais, postos de saúde, terminais de ônibus, etc., e \"equipamentos comunitários\" - atividades comerciais e de prestação de serviços diversificadas. Foi transformada em linha de financiamento pelo Governo Brasileiro, sendo operada pelo grande agente implementador da política urbana do período, o Banco Nacional da Habitação - BNH, a partir de 1973. O Cura atendeu a mais de uma centena de municípios até 1985, quando o Banco foi formalmente extinto. A proposta pode ser considerada avançada para a época, seja por representar uma proposta de transição entre o \"planejamento urbano\" e o \"urbanismo pós-moderno\" que se consolidaria na década seguinte, seja por propor a participação da iniciativa privada no planejamento da cidade ou seja por propor como mecanismo para conter a valorização imobiliária das áreas \"curadas\", o aumento progressivo no tempo do imposto territorial urbano para os lotes vagos. Nosso trabalho procura mostrar essas várias facetas do Programa Cura, além de se preocupar em entender as possíveis conseqüências para as cidades e para os seus moradores da implantação de Projetos Cura. Para isso, estudamos várias análises do Programa, inclusive estudos de caso de Projetos Cura implantados em São Paulo (SP), Presidente Prudente (SP), Londrina (PR) e João Pessoa (PB). Nos preocupamos em realizar uma análise abrangente dessa proposta urbanística, que por sua qualidade e inovação, merece, em nossa opinião, o olhar atento dos estudiosos do urbanismo brasileiro.This paper analyzes the Cura Programme, an urban proposal developed in 1972 by the Brazilian architect Harry James Cole, which aimed at offering a kind of urban renewal of well-delimited neighborhoods through the implementation of infrastructure, public facilities - such as schools, nurseries, hospitals, health care centers, bus stations, and \"community equipment\" - commercial activities and services. The programme was turned into a credit line by the Brazilian Government in 1973, and the National Housing Bank (BNH) was assigned to manage it. The Cura Programme supported more than a hundred cities until 1985, when the Bank was formally extinguished. The programme was considered advanced for its time not only because it represented a transition proposal between \"urban planning\" and \"post-modern urbanism, which would be consolidated in Brazil in the following decade, but also because it proposed the private initiative participation in the planning of cities, and a mechanism to hold back the real state valorization, the annual increase of urban land taxes for not built up lots. This paper also shows many aspects of the Cura Programme and it tries to understand possible consequences of the Cura Programme to the cities and their inhabitants. For this reason, several studies of the programme were analyzed, including case studies of Cura Projects implemented in São Paulo (SP), Presidente Prudente (SP), Londrina (PR) and João Pessoa (PB). This study focused on carrying out a broad analysis of this urban proposal, which deserves, due to its quality and innovation, a close look from Brazilian urbanism experts.
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JOSEPH, MARIE-LINE. "La cure de desintoxication alcoolique : bilan d'une annee de soins a l'unite de cure de l'hopital du hainaut de valenciennes." Lille 2, 1990. http://www.theses.fr/1990LIL2M348.
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Boddapati, Aparna. "Modeling cure depth during photopolymerization of multifunctional acrylates." Thesis, Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/33934.
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The photopolymerization of multifunctional acrylates leads to the formation of a complex and insoluble network due to cross-linking. This characteristic is a useful property for stereolithography applications, where solid parts of the desired shape are cured using a pre-determined energy exposure profile. Traditionally, the required energy exposure is determined using a critical energy--depth of penetration, or Ec--Dp, model. The parameters Ec and Dp, are usually fit to experimental data at a specific resin composition and cure intensity. As a result, since the Ec--Dp model does not explicitly incorporate cure kinetics, it cannot be used for a different set of process conditions without first obtaining experimental data at the new conditions. Thus, the Ec--Dp model does not provide any insight when a new process needs to be developed, and the best processing conditions are unknown.
The kinetic model for multifunctional acrylate photopolymerization presented here is based on a set of ordinary differential equations (ODE), which can be used to predict part height versus exposure condition across varying resin compositions. Kinetic parameter information used in the model is obtained by fitting the model to double bond conversion data from Fourier Transform Infrared Spectroscopy (FTIR) measurements. An additional parameter, the critical conversion value, is necessary for determining the formation of a solid part of the desired height. The initial rate of initiation, Ri, combines all the factors that impact part height, and therefore, it is an important quantity that is required in order to find the critical conversion value. The critical conversion value is estimated using the Ri and Tgel value from microrheology measurements.
Information about network connectivity, which can be used to get properties such as molecular weight, cannot be derived from models using traditional mass-action kinetics for the cross-linking system. Therefore, in addition to modeling the reaction using the ODE based model, the results from a statistical model based on Kinetic Monte Carlo (KMC) principles are also shown here. The KMC model is applicable in situations where the impact of chain length on the kinetics or molecular weight evolution is of interest. For the present project, the detailed information from network connectivity was not required to make part height predictions, and the conversion information from the ODE model was sufficient.
The final results show that the kinetic ODE model presented here, based on the critical conversion value, captures the impact of process parameters such as initiator concentration, light intensity, and exposure time, on the final part height of the object. In addition, for the case of blanket cure samples, the part height predictions from the ODE model make comparable predictions to the Ec--Dp model. Thus, the ODE model presented here is a versatile tool that can be used to determine optimum operating conditions during process development.
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Dimopoulos, Athanasios. "Effect of carbon nanoparticle addition on epoxy cure." Thesis, Cranfield University, 2007. http://dspace.lib.cranfield.ac.uk/handle/1826/4076.
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The thesis reports studies of cure kinetics and the glass transition temperature advancements of three commercial epoxy resin systems: MY 750 / HY 5922 (Vantico), MTM 44 -1 (ACG) and 8552 (Hexcel Composites). This investigation was conducted with the utilisation of Differential Scanning Calorimetry (DSC) and Temperature Modulated DSC (TMDSC). Appropriate phenomenological cure kinetics models were built to predict the degree of cure as a function of temperature/time profile. The validity of superposition of dynamic and isothermal experimental data was established. Rheological measurements were performed in order to determine the gelation region under given cure conditions. The cure modelling methodology was validated against an international Round-Robin exercise led by the University of British Columbia (Canada). The effects of carbon nanoparticle incorporation on the cure kinetics and the glass transition temperature advancement of two of the epoxy systems were also studied. Cure kinetics models were developed for the nanocomposites containing commercial multiwalled carbon nanotubes and a direct comparison was made with the models of the neat resin systems. The glass transition temperature advancement is shown to be affected in the early stages of the cure. The state of the dispersion of the nanoparticles was studied in order to correlate it with the observed effects upon the cure and on the morphology of the cured samples. The presence of carbon nanotube clusters is shown to have an influence on the phase separation in the MTM 44-1 resin system. As a potential industrial application of this study, optical fibre refractometers were utilised as an on-line cure monitoring technique. A good correlation was established between the measured refractive index changes during the cure and the degree of cure predicted by the above mentioned models, for the neat resin systems and their nanocomposites.
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Dykeman, Donna. "Minimizing uncertainty in cure modeling for composites manufacturing." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/690.
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The degree of cure and temperature are consistent variables used in models to describe the state of material behaviour development for a thermoset during cure. Therefore, the validity of a cure kinetics model is an underlying concern when combining several material models to describe a part forming process, as is the case for process modeling. The goals of this work are to identify sources of uncertainty in the decision-making process from cure measurement by differential scanning calorimeter (DSC) to cure kinetics modeling, and to recommend practices for reducing uncertainty.
Variability of cure kinetics model predictions based on DSC measurements are investigated in this work by a study on the carbon-fiber-reinforced-plastic (CFRP) T800H/3900-2, an interlaboratory Round Robin comparison of cure studies on T800H/3900-2, and a literature review of cure models for Hexcel 8552. It is shown that variability between model predictions can be as large as 50% for some process conditions when uncertainty goes unchecked for decisions of instrument quality, material consistency, measurement quality, data reduction and modeling practices. The variability decreases to 10% when all of the above decisions are identical except for the data reduction and modeling practices.
In this work, recommendations are offered for the following practices: baseline selection, balancing heats of reaction, comparing data over an extensive temperature range (300 K), choosing appropriate models to describe a wide range of behaviour, testing model reliability, and visualization techniques for cure cycle selection. Specific insight is offered to the data reduction and analysis of thermoplastic-toughened systems which undergo phase separation during cure, as is the case for T800H/3900-2. The evidence of phase separation is a history-dependent Tg-α relationship. In the absence of a concise outline of best practices for cure measurement by DSC and modeling of complex materials, a list of guidelines based on the literature and the studies herein is proposed.
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Kallos, Alexander. "Characterization of cure of phenol formaldehyde foaming resin." Thesis, McGill University, 1987. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=63800.
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Wechsler, Daniel Steven Gary. "Immune mechanisms of cure in Trypanosoma musculi infection." Thesis, McGill University, 1987. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=75348.
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Trypanosoma musculi is a protozoan parasite which produces a characteristic, self-limiting murine infection of approximately three weeks duration; the infection comprises a growth phase, a plateau phase and an elimination phase. Following clearance of parasitaemia, a mouse is cured and immune to reinfection. The present studies examine the immune mechanisms which operate during the elimination phase.Passive transfer of plasma from an immune mouse to an infected recipient brings about rapid and complete clearance of parasitaemia in C57BL/6 mice. This curative activity is labile to heat treatment for 30 minutes at 56$ sp circ$C. A protein A- derived immunoglobulin fraction of immune plasma (IP) shares these properties. Further purification shows that the curative activity resides primarily in the IgG2a subclass, and that this antibody is intrinsically heat-labile. Complement component C3 (but not the lytic C5-C9 sequence) is necessary for antibody-mediated cure of infection. Cellular elements (macrophages) are also essential for elimination of parasitaemia to occur. The ultimate T. musculi effector mechanism thus requires the interaction of both humoral and cellular components.
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Zhou, Feifei, and 周飞飞. "Cure models for univariate and multivariate survival data." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B45700977.
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Powell, Graham. "In-situ cure monitoring of epoxy resins systems." Thesis, Brunel University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242971.
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Bootkul, Duangkhae. "Fibre sensor for cure monitoring in composite materials." Thesis, University of Sheffield, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.440917.
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O'Gara, Paula M. "Electron-beam cure of high-temperature resistant polymers." Thesis, University of Surrey, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274365.
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Kellond, Joanna Elizabeth Thornton. "The art of healing : psychoanalysis, culture and cure." Thesis, University of Sussex, 2015. http://sro.sussex.ac.uk/id/eprint/54447/.
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This thesis explores how we might think the relation between psychoanalysis and the cultural field through Donald Winnicott's concept of the environment, seeking to bring the concept into dialogue with more “classical” strands of psychoanalytic theorizing. A substantial introduction sets out the rationale behind the thesis by reading Freud and Winnicott in relation to the “classic” and the “romantic” (Strenger 1989), or the “negative” and “positive” (Rustin 2001), in psychoanalytic thought. It goes on to outline the value of bringing these tendencies together in order to think the relationship between psychoanalysis, culture and change. The chapters which follow move from psychoanalysis as a “cultural cure” – a method and discourse drawing on and feeding into a broad conception of cultural life – towards a notion of “culture as cure” informed by Winnicott's theory of the environment. Chapter one examines Freud's refusal of the “culture”/ “civilization” distinction and considers what it means for the idea of a cultural cure. Chapter two considers whether Winnicott's thinking about “culture” ultimately prioritises the aesthetic over the political. Chapter three uses Aldous Huxley's Brave New World ([1932] 1994) to explore an analogy between totalitarianism, technology and maternal care. Chapter four turns to the series In Treatment (HBO 2008-) to think about the intersections of therapy and technology in terms of reflection and recognition. Chapter five employs Ian McEwan's Saturday (2005) as a means to reflect on the capacity of culture to cure. Ultimately, I suggest that social “cure” may require more than “good-enough” cultural forms and objects, but Winnicott's “romantic” theorization of the aesthetic, coupled with a “classic” attention to structures of power and oppression may offer a means of thinking the relationship between psychoanalysis and culture in potentially transformative ways.