Academic literature on the topic 'Cunninghamella japonica'

Abstract The aim of this article is influence of the structure of lactones with the methylcyclohexene and dimethylcyclohexene ring on their biotransformation and antimicrobial activity. This work was based on the general remark that even the smallest change in the structure of a compound can affect its biological properties. The results of the biotransformation of four bicyclic unsaturated lactones with one or two methyl groups in the cyclohexene ring was tested using fifteen fungal strains (Fusarium species, Penicillium species, Absidia species, Cunninghamella japonica, and Pleurotus ostreatus) and five yeast strains (Yarrowia lipolytica, Rhodorula marina, Rhodorula rubra, Candida viswanathii, and Saccharomyces cerevisiae). During these transformations, new epoxylactone and hydroxylactone were obtained. The relationship between the substrate structure and the ability of the microorganisms to transform them were analysed. Only compounds with C–O bond of lactone ring in the equatorial position were transformed by fungus. All presented here lactones were examined also for their antimicrobial activity. It turned out that these compounds exhibited growth inhibition of bacteria and fungi, mainly Bacillus subtilis, Candida albicans, Aspergillus niger, and Penicillium expansum.

Дипломний проект складається з 124 аркушів пояснювальної записки, з використанням 88 літературних джерел та 3 аркушів креслень А1. Пояснювальна записка складається з вступу, п’яти розділів, що містять 23 рисунки, 2 таблиць, висновки і список літературних посилань. В роботі обрано та обґрунтовано технологію одержання ліпідів мукорових грибів. В проекті наведено обґрунтування вибору технології безперервного глибинного культивування мукорових грибів виду Cunninghamella japonica. Наведено характеристику продуценту та проаналізовано його фракційний склад. Розраховано матеріальний баланс процесу, наведено та описано технологічну та апаратурну схеми виробництва ліпідів, наведено поетапний опис технології отримання ліпідів мукорових грибів та параметри контролю етапів процесу, охорона праці та довкілля. Обрано ферментер об’ємом 50 м^3.
The diploma project consists of 124 pages of explanatory note, using 88 references and 3 sheets of drawings A1. The explanatory note consists of an introduction, five chapters containing 23 figures, 2 tables, conclusions and a list of references. The technology of obtaining lipids of flour fungi is selected and substantiated in the work. The project substantiates the choice of technology for continuous deep cultivation of flour mushrooms of the species Cunninghamella japonica. The characteristics of the producer are given and its fractional composition is analyzed. The material balance of the process is calculated, the technological and equipment schemes of lipid production are given and described, the step-by-step description of the technology of obtaining lipids of flour mushrooms and parameters of control of stages of the process, labor protection and environment are given. A 50 m^3 fermenter was selected.