Academic literature on the topic 'Cultural Memory'

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Journal articles on the topic "Cultural Memory"

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Laland, Kevin N., and Luke Rendell. "Cultural memory." Current Biology 23, no. 17 (September 2013): R736—R740. http://dx.doi.org/10.1016/j.cub.2013.07.071.

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Etkin, Nina. "Cultural Memory and Biodiversity.:Cultural Memory and Biodiversity." American Anthropologist 102, no. 4 (December 2000): 955–56. http://dx.doi.org/10.1525/aa.2000.102.4.955.

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Ryberg, Ingrid. "Queer Cultural Memory." lambda nordica 25, no. 1 (June 15, 2020): 122–26. http://dx.doi.org/10.34041/ln.v25.624.

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Kukkonen, Karin. "Popular Cultural Memory." Nordicom Review 29, no. 2 (November 1, 2008): 261–73. http://dx.doi.org/10.1515/nor-2017-0190.

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Abstract Conventions of genres, types and icons of popular culture are the shared knowledge of media audiences. Becoming acquainted with them through the reception of media texts resembles a socialisation process in its own right: It constitutes a community of media readers. The context knowledge they share is their popular cultural memory. On the level of the individual reading process, this context knowledge then provides the necessary guiding lines for understanding the connotative dimensions of a popular media text. Popular cultural memory is a repository of conventions and imagery that are continually reconstructed in contemporary popular culture. Drawing on J. Assmann’s writings on the functions and processes of collective memory, the present article develops popular cultural memory as a concept to describe the workings of context knowledge for media texts, while taking into consideration both the macrolevel of audience communities and the microlevel of the individual reading process. The comics series Fables by Bill Willingham (NY: DC Comics Vertigo, 2003-) will provide the example through which the article explores the functions of popular cultural memory in media texts, which can take shapes as different as the identification of genre, the stabilisation of intertextual reference chains or the creation of round characters and complex reflexivity.
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Barlow, Melinda. "Personal History, Cultural Memory." Afterimage 21, no. 4 (November 1, 1993): 8–12. http://dx.doi.org/10.1525/aft.1993.21.4.8.

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Voigt, Vilmos. "On proxy cultural memory." Acta Ethnographica Hungarica 59, no. 2 (December 2014): 389–95. http://dx.doi.org/10.1556/aethn.58.2014.2.8.

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Deodhar, Bhakti. "Inside Contested Cultural Memory." German Politics and Society 39, no. 3 (September 1, 2021): 46–69. http://dx.doi.org/10.3167/gps.2021.390303.

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This article explores the role played by the Alternative für Deutschland (AfD), a German right-wing political party, in the politics of memory in and of Dresden. Based on ethnographic fieldwork among AfD members and observation of the party’s organization, the article demonstrates that the performative acts of local AfD members bear crucial significance in explaining the party’s attempts to challenge the mainstream memory discourse that is linked to the centrality of the Holocaust. I argue that party members not only draw upon established discursive narratives of Germany’s victimhood, but also find ways to skillfully adapt their messages in their efforts to achieve legitimacy. Their performative contestations have enabled the AfD to be both a beneficiary and an instigator of the shifting boundaries of what is considered admissible in Germany’s official culture of memorialization.
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Deodhar, Bhakti. "Inside Contested Cultural Memory." German Politics and Society 39, no. 3 (September 1, 2021): 46–69. http://dx.doi.org/10.3167/gps.2021.390303.

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This article explores the role played by the Alternative für Deutschland (AfD), a German right-wing political party, in the politics of memory in and of Dresden. Based on ethnographic fieldwork among AfD members and observation of the party’s organization, the article demonstrates that the performative acts of local AfD members bear crucial significance in explaining the party’s attempts to challenge the mainstream memory discourse that is linked to the centrality of the Holocaust. I argue that party members not only draw upon established discursive narratives of Germany’s victimhood, but also find ways to skillfully adapt their messages in their efforts to achieve legitimacy. Their performative contestations have enabled the AfD to be both a beneficiary and an instigator of the shifting boundaries of what is considered admissible in Germany’s official culture of memorialization.
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Cao, Zhongkai, and Zaihong Zhang. "Cultural Memory of Language." Australian Journal of Linguistics 38, no. 1 (September 15, 2016): 132–35. http://dx.doi.org/10.1080/07268602.2016.1226681.

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Coplan, David B. "Popular history; Cultural memory." Critical Arts 14, no. 2 (January 2000): 122–44. http://dx.doi.org/10.1080/02560040085310121.

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Dissertations / Theses on the topic "Cultural Memory"

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Lobe, Clifford. "Un-settling memory, cultural memory and post-colonialism." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ60207.pdf.

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Abuelma'Atti, Z. M. T. "Translation and cultural representation : globalizing texts, localizing cultures." Thesis, University of Salford, 2005. http://usir.salford.ac.uk/26494/.

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Intercultural contacts that allowed for cross-cultural fertilization were made possible through translation. Translation, in the main, has been understood as an activity that requires knowing the source and target languages to achieve the same informational and emotive effects of the source language in the target one. Yet, the search for equivalence led translators to realize that linguistic terms do not appear in isolation; they are part and parcel of a culture. Fairclough's stipulation, from a critical discourse analysis point of view, that language as discourse is invested with ideologies that organize socially shared attitudes, engages language in a complex relationship with social cognition, power and culture. The characterization of language as such leads to the production of a master discourse through which identity, similarity and difference are identified. Within the context of globalization, intercultural translation, particularly between cultures that are unequal politically and economically, adheres to a master discourse of translation and representation through which the other is received, accepted and/ or refused then reproduced. Consequently, source texts and people are transformed into signs familiar to the translating community constructing as such domestic identities of foreign cultures. Drawing on translation from Arabic, and in light of critical discourse analysis approaches, the translation of culture and the culture of translation, the research considers the case of Nawal El-Saadawi. The aim is to explore and examine how the constraints and disciplinary demands of the master discourse of translation and representation affect the translation traffic from Arabic into English. In a rapidly globalizing world, the ethics of translation postulate that translation should create a readership that is open to cultural differences for a true globalization of cultures, and improve cultural relations rather than being a tool for reinforcing and diffusing existing representationsa nd images of one culture about the other
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Brown, Judith Ashley. "Cultural memory in Crimea : history, memory and place in Sevastopol." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708062.

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Morelock, Ela Molina. "Cultural memory in Elena Poniatowska's Tinisima." Oxford, Ohio : Miami University, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=miami1101364954.

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Peters, Philip. "Historical cultural memory celebrated through architecture." This title; PDF viewer required. Home page for entire collection, 2006. http://archives.udmercy.edu:8080/dspace/handle/10429/9.

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Scott, Carol Ann. "Roman patriarchy, women and cultural memory." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20165.

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This study explores female agency within Roman patriarchy. It brings recent developments in gender theory to an analysis of patriarchy and the experience of women within it. It cautions against assumptions that patriarchy was a fixed and monolithic system which impacted women disproportionately, without first considering its implications for both men and women and examining how it operated in daily interactions. It questions perceptions that patriarchy automatically subordinated women and denied them agency. In researching this line of questioning, it considers two meanings of subordination. While ‘subordinate’ can entail control over another, a second definition refers to social preferencing in terms of the ‘importance’ or ‘status’ of one gender compared to another. In considering evidence for both aspects of subordination, it finds that Roman patriarchy was a complex and nuanced system, one in which the parameters of women’s experience had as many allowances as it did constraints and one which respected and honored its women. This study then tests these findings through a new paradigm of inquiry- women’s position in cultural memory. This is undertaken through a consideration of both the active role of women in preserving the cultural memory of Rome through the performance of religious ritual and the representation of women in the literary construction of Rome’s cultural memory by the 1st century BCE author, Livy.
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Wilson, Kevin Arthur. "From memory to history American cultural memory of the Vietnam War /." Oxford, Ohio : Miami University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=miami1153500782.

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Bavidge, Eleanor. "Heterotopias of memory : cultural memory in and around Newcastle upon Tyne." Thesis, University of Sunderland, 2009. http://sure.sunderland.ac.uk/3558/.

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The aim of the research is to examine the multiple spatial frameworks and materially manifested forms of memory by applying current memory studies theory to four areas of memorial experience: personal memory, civic memory, tourism and film. The thesis looks at memory practices based in the North East, particularly those that take place in Newcastle upon Tyne, and explores how the city is remembered in specific memory practices and institutions. Combining work in memory studies and cultural geography, the thesis highlights how memory is spatialized and is particularly concerned with the city that shapes, and is shaped by, memory and memory practices. Changes have taken place in the relationship between space, place and temporality that have affected memory and practices of memorialization. At first glance, the technologies we use and the spaces we inhabit can be interpreted as leading to a pervasive amnesia. The thesis challenges this assumption. It proposes that the concept of heterotopia provides a critical mode of reading memory spaces offering a more positive account of the way memory is currently being experienced. The thesis looks at how memory is realized in the fabric of the city and how the historical city itself is represented through the discursive practices of memorial public art, the museum and the cinema, creating a collective cultural memory. The particular contribution that this thesis makes is that it tests the explanatory power of the concept of heterotopia in relation to memorial sites and it applies memory studies to the city of Newcastle in a time of transition and renewal.
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Wilson, Kevin A. "From Memory to History: American Cultural Memory of the Vietnam War." Miami University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=miami1153500782.

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Cash, Deborah Dyer. "Cultural differences on the children's memory scale." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-1621.

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Books on the topic "Cultural Memory"

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Wehrs, Donald R., Suzanne Nalbantian, and Don M. Tucker. Cultural Memory. New York: Routledge, 2022. http://dx.doi.org/10.4324/9781003205135.

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Cultural memory and biodiversity. Tucson: University of Arizona Press, 1998.

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Berger, Sandra, and Julia Schütze. Film and Cultural Memory. Edited by Astrid Erll and Stephanie Wodianka. Berlin, New York: Walter de Gruyter, 2008. http://dx.doi.org/10.1515/9783110209310.

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Congress, International Comparative Literature Association. Travel writing and cultural memory. Amsterdam: Rodopi, 2000.

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The cultural memory of language. London: Bloomsbury, 2014.

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Cultural memory in Biblical exegesis. Piscataway, NJ: Gorgias Press, 2012.

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Kubal, Timothy. Cultural Movements and Collective Memory. New York: Palgrave Macmillan US, 2008. http://dx.doi.org/10.1057/9780230615762.

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Carstens, Pernille, Trine Bjørnung Hasselbalch, Niels Peter Lemche, Izaak Hulster, Dolores Kamrada, Rüdiger Schmitt, Terje Stordalen, et al., eds. Cultural Memory in Biblical Exegesis. Piscataway, NJ, USA: Gorgias Press, 2012. http://dx.doi.org/10.31826/9781463234690.

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Parfitt, Clare, ed. Cultural Memory and Popular Dance. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-71083-5.

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Hedges, Inez. World Cinema and Cultural Memory. London: Palgrave Macmillan UK, 2015. http://dx.doi.org/10.1057/9781137465122.

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Book chapters on the topic "Cultural Memory"

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Hogan, Patrick Colm. "Cultural Memory." In Cultural Memory, 107–20. New York: Routledge, 2022. http://dx.doi.org/10.4324/9781003205135-10.

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Lotman, Juri. "Cultural Memory." In Juri Lotman - Culture, Memory and History, 139–48. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-14710-5_10.

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Assmann, Aleida. "Cultural Memory." In Social Trauma – An Interdisciplinary Textbook, 25–36. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-47817-9_3.

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Schilz, Andrea, and Malte Rehbein. "Cultural Memory." In Handbook Industry 4.0, 1177–91. Berlin, Heidelberg: Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-64448-5_63.

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Erll, Astrid. "Cultural Memory." In English and American Studies, 238–42. Stuttgart: J.B. Metzler, 2012. http://dx.doi.org/10.1007/978-3-476-00406-2_15.

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Ißler, Roland Alexander. "Cultural Memory." In The Bonn Handbook of Globality, 807–19. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-90382-8_6.

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Wertsch, James V., Henry L. Roediger, and Christopher L. Zerr. "Collective Memory." In Cultural Memory, 95–106. New York: Routledge, 2022. http://dx.doi.org/10.4324/9781003205135-9.

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Wehrs, Donald R. "Introduction." In Cultural Memory, 1–17. New York: Routledge, 2022. http://dx.doi.org/10.4324/9781003205135-1.

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Wehrs, Donald R. "Neural Pluralism and Cultural Memory in Eliot's The Waste Land and Akhmatova's Requiem." In Cultural Memory, 185–98. New York: Routledge, 2022. http://dx.doi.org/10.4324/9781003205135-16.

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Reynolds, David S. "The U.S. Civil War and Cultural Memory." In Cultural Memory, 137–57. New York: Routledge, 2022. http://dx.doi.org/10.4324/9781003205135-12.

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Conference papers on the topic "Cultural Memory"

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Meng, Suqing. "Cultural Effects of Human Memory." In 2022 International Conference on Social Sciences and Humanities and Arts (SSHA 2022). Paris, France: Atlantis Press, 2022. http://dx.doi.org/10.2991/assehr.k.220401.149.

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Aydın, Elif, and Berna Dikçınar Sel. "Reading Cultural Heritage of Beşiktaş Through Society, Memory and Identity of the Place." In 4th International Conference of Contemporary Affairs in Architecture and Urbanism – Full book proceedings of ICCAUA2020, 20-21 May 2021. Alanya Hamdullah Emin Paşa University, 2021. http://dx.doi.org/10.38027/iccaua2021tr0046n23.

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The constant change of the meaning of the physical environment for the individual and society during the experience of space in daily life detract the spatial perception from cultural values. The formation of valuable / important perception regarding the physical space elements that are disconnected from the interaction of space, society and culture causes place attachment status to change and negatively affects the preservation of cultural heritage values. In other words, it increases the problem of preserving cultural heritage values by losing the meaning of cultural values that are a part of the physical environment in the relationship between space and society. In this context, in Beşiktaş, which has been settled for many years and has traces of different cultures, as a result of the differentiation of the relationship between the space and the individual due to technological and economic developments, the interaction with cultural values is gradually decreasing during the experience of space. In this study, using the questionnaire method, the status of place attachment is examined through interviews with daily users of Beşiktaş by using open-ended and 5-likert scale questions. The aim of the research is to analyze the cultural heritage values in the context of the relationship between society and space in Besiktas.
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Haake, Susanne, and Wolfgang Muller. "New memory spaces for cultural history." In 2015 Digital Heritage. IEEE, 2015. http://dx.doi.org/10.1109/digitalheritage.2015.7413921.

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Irina, Ponizovkina, and Agibalova Elena. "Collective Memory and Cultural-mythological Space." In Proceedings of the 5th International Conference on Education, Language, Art and Inter-cultural Communication (ICELAIC 2018). Paris, France: Atlantis Press, 2018. http://dx.doi.org/10.2991/icelaic-18.2018.159.

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Li, Shuyi. "Cultural Memory Construction Strategy of ‘Inheriting China’." In 2022 3rd International Conference on Language, Art and Cultural Exchange(ICLACE 2022). Paris, France: Atlantis Press, 2022. http://dx.doi.org/10.2991/assehr.k.220706.028.

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Garrido, Valeriia Vladimirovna. "Main Symbols In Cultural Memory Of China." In International Conference on Social and Cultural Transformations in the Context of Modern Globalism. European Publisher, 2021. http://dx.doi.org/10.15405/epsbs.2021.11.79.

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Loyko, O., and N. Fyodorova. "THE NATURE AND LANDSCAPE OF SOCIAL MEMORY IN POSTMODERN SOCIETY." In Man and Nature: Priorities of Modern Research in the Area of Interaction of Nature and Society. LCC MAKS Press, 2021. http://dx.doi.org/10.29003/m2588.s-n_history_2021_44/76-80.

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The article is devoted to the study of social memory as a special way of preserving the value-semantic field of culture. The article examines the cultural and historical landscape of social memory, its difference from historical memory, and concludes that in postmodern society there is a natural process of reconstruction-reactivation – recategorization of the content of social memory. It is suggested that this process, being natural and historically determined, nevertheless needs constant adjustments in order to objectively understand its content.
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Aytes, Ayhan. "Designing the new memory space for cultural heritage." In ACM SIGGRAPH 2004 Educators program. New York, New York, USA: ACM Press, 2004. http://dx.doi.org/10.1145/1186107.1186145.

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Augusto Cardona Olaya, Felix. "Cultural landscape memory artifacts visibilization, a codesign strategy." In PDC '20: Participatory Design Conference 2020 - Participation Otherwise. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3384772.3385130.

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Bereznyakov, Dmitry V., and Sergey V. Kozlov. "Memory politics “from above” from political communicative studies perspective." In Communication and Cultural Studies: History and Modernity. Novosibirsk State University, 2021. http://dx.doi.org/10.25205/978-5-4437-1258-1-15-20.

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Reports on the topic "Cultural Memory"

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Andrews, William. Shigenobu Fusako and the Haze of Cultural Memory. Critical Asian Studies, June 2022. http://dx.doi.org/10.52698/lfve6790.

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Rosenkranz, Leah. History and Memory in the Intersectionality of Heritage Sites and Cultural Centers in the Pacific Northwest and Hawai'i. Portland State University Library, January 2000. http://dx.doi.org/10.15760/etd.7499.

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Титаренко, Дмитро Миколайович, and Таня Пентер. Local memory on war, German occupation and postwar years. An oral history project in the Donbass. Cahiers du monde Russe, Vol. 52, No. 2/3, 2011. http://dx.doi.org/10.31812/123456789/6476.

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This article presents the findings of a small oral history project carried out during the years 2001-2010 in the Eastern Ukrainian Donbass region. We learn from the interviews that loyalties were rather fragile and changed quite frequently during the war. The sharp lines of definition and categorisation which historians have created in dealing with the past do not fit wartime reality. Many people collaborated at one time and participated in Soviet resistance or fought in the Red Army at another. There were no clear lines between collaboration and resistance, but rather moral grey zones. Experiences of the occupation were diverse, and besides, experiences of terror and violence also included cultural and working experiences as well as various personal relationships with the German enemy. Therefore the authors argue for much more integrated research approaches trying to combine the wide range of different wartime experiences.
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Hall, Mark, and Neil Price. Medieval Scotland: A Future for its Past. Society of Antiquaries of Scotland, September 2012. http://dx.doi.org/10.9750/scarf.09.2012.165.

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The main recommendations of the panel report can be summarised under five key headings. Underpinning all five areas is the recognition that human narratives remain crucial for ensuring the widest access to our shared past. There is no wish to see political and economic narratives abandoned but the need is recognised for there to be an expansion to more social narratives to fully explore the potential of the diverse evidence base. The questions that can be asked are here framed in a national context but they need to be supported and improved a) by the development of regional research frameworks, and b) by an enhanced study of Scotland’s international context through time. 1. From North Britain to the Idea of Scotland: Understanding why, where and how ‘Scotland’ emerges provides a focal point of research. Investigating state formation requires work from Medieval Scotland: a future for its past ii a variety of sources, exploring the relationships between centres of consumption - royal, ecclesiastical and urban - and their hinterlands. Working from site-specific work to regional analysis, researchers can explore how what would become ‘Scotland’ came to be, and whence sprang its inspiration. 2. Lifestyles and Living Spaces: Holistic approaches to exploring medieval settlement should be promoted, combining landscape studies with artefactual, environmental, and documentary work. Understanding the role of individual sites within wider local, regional and national settlement systems should be promoted, and chronological frameworks developed to chart the changing nature of Medieval settlement. 3. Mentalities: The holistic understanding of medieval belief (particularly, but not exclusively, in its early medieval or early historic phase) needs to broaden its contextual understanding with reference to prehistoric or inherited belief systems and frames of reference. Collaborative approaches should draw on international parallels and analogues in pursuit of defining and contrasting local or regional belief systems through integrated studies of portable material culture, monumentality and landscape. 4. Empowerment: Revisiting museum collections and renewing the study of newly retrieved artefacts is vital to a broader understanding of the dynamics of writing within society. Text needs to be seen less as a metaphor and more as a technological and social innovation in material culture which will help the understanding of it as an experienced, imaginatively rich reality of life. In archaeological terms, the study of the relatively neglected cultural areas of sensory perception, memory, learning and play needs to be promoted to enrich the understanding of past social behaviours. 5. Parameters: Multi-disciplinary, collaborative, and cross-sector approaches should be encouraged in order to release the research potential of all sectors of archaeology. Creative solutions should be sought to the challenges of transmitting the importance of archaeological work and conserving the resource for current and future research.
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Halych, Valentyna. SERHII YEFREMOV’S COOPERATION WITH THE WESTERN UKRAINIAN PRESS: MEMORIAL RECEPTION. Ivan Franko National University of Lviv, February 2021. http://dx.doi.org/10.30970/vjo.2021.49.11055.

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The subject of the study is the cooperation of S. Efremov with Western Ukrainian periodicals as a page in the history of Ukrainian journalism which covers the relationship of journalists and scientists of Eastern and Western Ukraine at the turn of the XIX-XX centuries. Research methods (biographical, historical, comparative, axiological, statistical, discursive) develop the comprehensive disclosure of the article. As a result of scientific research, the origins of Ukrainocentrism in the personality of S. Efremov were clarified; his person as a public figure, journalist, publisher, literary critic is multifaceted; taking into account the specifics of the memoir genre and with the involvement of the historical context, the turning points in the destiny of the author of memoirs are interpreted, revealing cooperation with Western Ukrainian magazines and newspapers. The publications ‘Zoria’, ‘Narod’, ‘Pravda’, ‘Bukovyna’, ‘Dzvinok’, are secretly got into sub-Russian Ukraine, became for S. Efremov a spiritual basis in understanding the specifics of the national (Ukrainian) mass media, ideas of education in culture of Ukraine at the end of XIX century, its territorial integrity, and state independence. Memoirs of S. Efremov on cooperation with the iconic Galician journals ‘Notes of the Scientific Society after the name Shevchenko’ and ‘Literary-Scientific Bulletin’, testify to an important stage in the formation of the author’s worldview, the expansion of the genre boundaries of his journalism, active development as a literary critic. S. Yefremov collaborated most fruitfully and for a long time with the Literary-Scientific Bulletin, and he was impressed by the democratic position of this publication. The author’s comments reveal a long-running controversy over the publication of a review of the new edition of Kobzar and thematically related discussions around his other literary criticism, in which the talent of the demanding critic was forged. S. Efremov steadfastly defended the main principles of literary criticism: objectivity and freedom of author’s thought. The names of the allies of the Ukrainian idea L. Skochkovskyi, O. Lototskyi, O. Konyskyi, P. Zhytskyi, M. Hrushevskyi in S. Efremov’s memoirs unfold in multifaceted portrait descriptions and function as historical and cultural facts that document the pages of the author’s biography, record his activities in space and time. The results of the study give grounds to characterize S. Efremov as the first professional Ukrainian-speaking journalist.
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Elmann, Anat, Orly Lazarov, Joel Kashman, and Rivka Ofir. therapeutic potential of a desert plant and its active compounds for Alzheimer's Disease. United States Department of Agriculture, March 2015. http://dx.doi.org/10.32747/2015.7597913.bard.

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We chose to focus our investigations on the effect of the active forms, TTF and AcA, rather than the whole (crude) extract. 1. To establish cultivation program designed to develop lead cultivar/s (which will be selected from the different Af accessions) with the highest yield of the active compounds TTF and/or achillolide A (AcA). These cultivar/s will be the source for the purification of large amounts of the active compounds when needed in the future for functional foods/drug development. This task was completed. 2. To determine the effect of the Af extract, TTF and AcA on neuronal vulnerability to oxidative stress in cultured neurons expressing FAD-linked mutants.Compounds were tested in N2a neuroblastoma cell line. In addition, we have tested the effects of TTF and AcA on signaling events promoted by H₂O₂ in astrocytes and by β-amyloid in neuronal N2a cells. 3. To determine the effect of the Af extract, TTF and AcA on neuropathology (amyloidosis and tau phosphorylation) in cultured neurons expressing FAD-linked mutants. 4. To determine the effect of A¦ extract, AcA and TTF on FAD-linked neuropathology (amyloidosis, tau phosphorylation and inflammation) in transgenic mice. 5. To examine whether A¦ extract, TTF and AcA can reverse behavioral deficits in APPswe/PS1DE9 mice, and affect learning and memory and cognitive performance in these FAD-linked transgenic mice. Background to the topic.Neuroinflammation, oxidative stress, glutamate toxicity and amyloid beta (Ab) toxicity are involved in the pathogenesis of Alzheimer's diseases. We have previously purified from Achilleafragrantissimatwo active compounds: a protective flavonoid named 3,5,4’-trihydroxy-6,7,3’-trimethoxyflavone (TTF, Fl-72/2) and an anti-inflammatory sesquiterpenelactone named achillolide A (AcA). Major conclusions, solutions, achievements. In this study we could show that TTF and AcA protected cultured astrocytes from H₂O₂ –induced cell death via interference with cell signaling events. TTF inhibited SAPK/JNK, ERK1/2, MEK1 and CREBphosphorylation, while AcA inhibited only ERK1/2 and MEK1 phosphorylation. In addition to its protective activities, TTF had also anti-inflammatory activities, and inhibited the LPS-elicited secretion of the proinflammatorycytokinesInterleukin 6 (IL-6) and IL-1b from cultured microglial cells. Moreover, TTF and AcA protected neuronal cells from glutamate and Abcytotoxicity by reducing the glutamate and amyloid beta induced levels of intracellular reactive oxygen species (ROS) and via interference with cell signaling events induced by Ab. These compounds also reduced amyloid precursor protein net processing in vitro and in vivo in a mouse model for Alzheimer’s disease and improvedperformance in the novel object recognition learning and memory task. Conclusion: TTF and AcA are potential candidates to be developed as drugs or food additives to prevent, postpone or ameliorate Alzheimer’s disease. Implications, both scientific and agricultural.The synthesis ofAcA and TTF is very complicated. Thus, the plant itself will be the source for the isolation of these compounds or their precursors for synthesis. Therefore, Achilleafragrantissima could be developed into a new crop with industrial potential for the Arava-Negev area in Israel, and will generate more working places in this region.
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7

Yahav, Shlomo, John Brake, and Noam Meiri. Development of Strategic Pre-Natal Cycling Thermal Treatments to Improve Livability and Productivity of Heavy Broilers. United States Department of Agriculture, December 2013. http://dx.doi.org/10.32747/2013.7593395.bard.

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The necessity to improve broiler thermotolerance and live performance led to the following hypothesis: Appropriate comprehensive incubation treatments that include significant temperature management changes will promote angiogenesis and will improve acquisition of thermotolerance and carcass quality of heavy broilers through epigenetic adaptation. It was based on the following questions: 1. Can TM during embryogenesis of broilers induce a longer-lasting thermoregulatory memory (up to marketing age of 10 wk) that will improve acquisition of thermotolerance as well as increased breast meat yield in heavy broilers? 2. The improved sensible heat loss (SHL) suggests an improved peripheral vasodilation process. Does elevated temperature during incubation affect vasculogenesis and angiogenesis processes in the chick embryo? Will such create subsequent advantages for heavy broilers coping with adverse hot conditions? 3. What are the changes that occur in the PO/AH that induce the changes in the threshold response for heat production/heat loss based on the concept of epigenetic temperature adaptation? The original objectives of this study were as follow: a. to assess the improvement of thermotolerance efficiency and carcass quality of heavy broilers (~4 kg); b. toimproveperipheral vascularization and angiogenesis that improve sensible heat loss (SHL); c. to study the changes in the PO/AH thermoregulatory response for heat production/losscaused by modulating incubation temperature. To reach the goals: a. the effect of TM on performance and thermotolerance of broilers reared to 10 wk of age was studied. b. the effect of preincubation heating with an elevated temperature during the 1ˢᵗ 3 to 5 d of incubation in the presence of modified fresh air flow coupled with changes in turning frequency was elucidated; c.the effect of elevated temperature on vasculogenesis and angiogenesis was determined using in ovo and whole embryo chick culture as well as HIF-1α VEGF-α2 VEGF-R, FGF-2, and Gelatinase A (MMP2) gene expression. The effects on peripheral blood system of post-hatch chicks was determined with an infrared thermal imaging technique; c. the expression of BDNF was determined during the development of the thermal control set-point in the preoptic anterior hypothalamus (PO/AH). Background to the topic: Rapid growth rate has presented broiler chickens with seriousdifficulties when called upon to efficiently thermoregulate in hot environmental conditions. Being homeotherms, birds are able to maintain their body temperature (Tb) within a narrow range. An increase in Tb above the regulated range, as a result of exposure to environmental conditions and/or excessive metabolic heat production that often characterize broiler chickens, may lead to a potentially lethal cascade of irreversible thermoregulatory events. Exposure to temperature fluctuations during the perinatal period has been shown to lead to epigenetic temperature adaptation. The mechanism for this adaptation was based on the assumption that environmental factors, especially ambient temperature, have a strong influence on the determination of the “set-point” for physiological control systems during “critical developmental phases.” Recently, Piestunet al. (2008) demonstrated for the first time that TM (an elevated incubation temperature of 39.5°C for 12 h/d from E7 to E16) during the development/maturation of the hypothalamic-hypophyseal-thyroid axis (thermoregulation) and the hypothalamic-hypophyseal-adrenal axis (stress) significantly improved the thermotolerance and performance of broilers at 35 d of age. These phenomena raised two questions that were addressed in this project: 1. was it possible to detect changes leading to the determination of the “set point”; 2. Did TM have a similar long lasting effect (up to 70 d of age)? 3. Did other TM combinations (pre-heating and heating during the 1ˢᵗ 3 to 5 d of incubation) coupled with changes in turning frequency have any performance effect? The improved thermotolerance resulted mainly from an efficient capacity to reduce heat production and the level of stress that coincided with an increase in SHL (Piestunet al., 2008; 2009). The increase in SHL (Piestunet al., 2009) suggested an additional positive effect of TM on vasculogenesis and angiogensis. 4. In order to sustain or even improve broiler performance, TM during the period of the chorioallantoic membrane development was thought to increase vasculogenesis and angiogenesis providing better vasodilatation and by that SHL post-hatch.
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8

‘Understanding developmental cognitive science from different cultural perspectives’ – In Conversation with Tochukwu Nweze. ACAMH, October 2020. http://dx.doi.org/10.13056/acamh.13666.

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Tochukwu Nweze, lecturer in the Department of Psychology, University of Nigeria, Nsukka and, PhD student in MRC Cognition and Brain Sciences Unit, University of Cambridge talks about his recent paper on parentally deprived Nigerian children having enhanced working memory ability, how important is it to study cultural differences in cognitive adaption during and following periods of adversity, and how can mental health professionals translate this understanding of difference into their work.
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