Relevant bibliographies by topics / CTMs

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'CTMs'

Author: Grafiati
Published: 4 June 2021
Last updated: 5 February 2022

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Journal articles on the topic "CTMs"

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Wu, Fengjie, Jun Zhu, Yongjiang Mao, Xiaomei Li, Baoguang Hu, and Dianliang Zhang. "Associations between the Epithelial-Mesenchymal Transition Phenotypes of Circulating Tumor Cells and the Clinicopathological Features of Patients with Colorectal Cancer." Disease Markers 2017 (2017): 1–6. http://dx.doi.org/10.1155/2017/9474532.

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In this study, we identified CTCs using the previously reported CanPatrol CTC enrichment technique from peripheral blood samples of 126 patients with colorectal cancer (CRC) and found that CTCs could be classified into three subpopulations based on expression of epithelial cell adhesion molecule (EpCAM) (E-CTCs), the mesenchymal cell marker vimentin (M-CTCs), or both EpCAM and vimentin (biphenotypic E/M-CTCs). Circulating tumor microemboli (CTMs) were also identified in peripheral blood samples. Meanwhile, E-CTCs, M-CTCs, E/M-CTCs, and CTMs were detected in 76.98%, 42.06%, 56.35%, and 36.51% of the 126 patients, respectively. Interestingly, the presence of CTMs and each CTC subpopulation was significantly associated with blood lymphocyte counts and tumor-node-metastasis stage (P<0.001). Lymphocyte counts and the neutrophil-to-lymphocyte ratio (NLR) in patients lacking CTCs were significantly different from those in patients testing positive for CTMs and each CTC subpopulation (P<0.001). Our results indicate that tumor metastasis is more significantly associated with the presence of CTMs and M-CTCs than with other CTC subpopulations and suggest that EMT may be involved in CTC evasion of lymphocyte-mediated clearance.
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Chen, Yang, Jiajia Yuan, Yanyan Li, Xue Li, Ying Yang, Jian Li, Yilin Li, and Lin Shen. "Profiling heterogenous sizes of circulating tumor microemboli to track therapeutic resistance and prognosis in advanced gastric cancer." Human Cell 34, no. 5 (June 21, 2021): 1446–54. http://dx.doi.org/10.1007/s13577-021-00568-2.

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AbstractCirculating tumor microemboli (CTM) aggregated by ≥ 2 circulating tumor cells (CTCs) are more migratory than single CTCs. Aside from the plasticity in their molecular characteristics, which have been considered tumor migration, CTM also possesses high size heterogeneity. This study, therefore, systematically investigated the heterogeneous sizes of CTM and their involvement in therapeutic resistance in 114 patients with advanced gastric cancer (GC) using a pre-established surface molecule-independent subtraction enrichment (SE)-iFISH strategy. CTM, which was pre-therapeutically detected in 33.3% of GC patients, can further form in another 34.78% of patients following chemo-/targeted therapies. The presence of CTM is relevant to liver metastasis as well as higher CTC levels (≥ 5/6 mL). Further size-based profiling of GC-CTM revealed that CTM with 2 CTCs (CTM2) was the dominant subtype, accounting for 50.0% of all detected GC-CTMs. However, CTM with 3–4 CTCs (CTM3–4) specifically associates with chemo-/targeted therapeutic resistance and inferior prognosis. Patients with ≥ 1 CTM3–4/6 mL have shorter median progression-free survival and median overall survival. Unlike CTM2 and CTM3–4, which are detectable in pre-therapy and post-therapy, larger aggregated CTM≥5 (CTM with ≥ 5 CTCs) was only intra-therapeutically detected in four HER2+ GC patients, of which three experienced liver metastases. Obtained results suggested that the cluster size of GC-CTM should be dynamically profiled beyond pre-therapeutic whole CTM enumeration in terms of chemo-/targeted resistance or metastasis monitoring. GC-CTM3–4 could be a potential indicator of therapeutic resistance, while the dynamic presence of GC-CTM≥5 implies liver metastasis in HER2+ GC patients.
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SANTOS, Enrico. "Biológia das células-tronco mesenquimais de felinos obtidas a partir de nichos presentes no tecido adiposo objetivando sua aplicação terapêutica na medicina veterinária." Revista Eletrônica Científica da UERGS 4, no. 3 (October 23, 2018): 368–79. http://dx.doi.org/10.21674/2448-0479.43.368-379.

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O tecido adiposo vêm representando uma fonte em potencial para a obtenção de células-tronco mesenquimais (CTMs). Estudos recentes têm demonstrado que as CTMs apresentam potencial de utilização tanto na pesquisa básica como aplicada. Podendo ser obtidas, em grandes quantidades, por meio de anestesia local e com o mínimo de desconforto, as CTMs vêm sendo objeto de intensa pesquisa. Neste estudo, o tecido adiposo de felino, obtido por meio de biópsia realizada na região subcutânea, foi processado de forma a obter uma população celular morfologicamente homogênea. As células-tronco mesenquimais derivadas do tecido adiposo felinos (CTMs-TAF) foram mantidas, in vitro, em crescimento exponencial até a 9ª passagem apresentando-se como uma população estável e com baixos níveis de senescência. As CTMs-TAF foram capazes de se diferenciarem, in vitro em células adipogênicas, condrogênicas e osteogênicas na presença de factores de indução linhagem específica. Quando injectado em camundongos nude, as CTMs-TAF não foram capazes de dar origem a teratocarcinomas. Estes resultados demonstram de que as CTMs-TAF possuem propriedades que sugerem a sua possível utilização na terapia celular.
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Patricio, L. F. L., C. L. K. Rebelatto, P. R. S. Brofman, B. B. Maciel, O. C. Beltrame, H. F. V. Brito, and R. Locatelli-Dittrich. "Isolamento e caracterização de células mesenquimais do tecido adiposo de cães." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 65, no. 4 (August 2013): 946–54. http://dx.doi.org/10.1590/s0102-09352013000400002.

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As células-tronco mesenquimais (CTMs) diferenciam-se em várias linhagens e têm potencial de utilização na medicina regenerativa. As CTMs podem ser isoladas de vários tecidos de animais adultos. O objetivo deste estudo foi o isolamento das CTMs do tecido adiposo de cães, seu cultivo e diferenciação. Foram coletadas amostras de tecido adiposo subcutâneo de cinco cães. As CTMs foram isoladas, obtendo-se 146.803 (±49.533) células/g, cultivadas e diferenciadas em osteoblastos, adipócitos e condrócitos. Avaliaram-se a cinética do crescimento, a morfologia e a viabilidade celular. A caracterização citoquímica comprovou a natureza mesenquimal das células isoladas. O cultivo foi iniciado com 20.000 células/mL, verificando-se crescimento rápido até 72 horas (220.000 células/mL), fase exponencial entre 72 e 192 horas (455.000 células/mL), seguida de platô por saturação da densidade com 240 horas (355.000 células/mL). A viabilidade celular variou entre 96 e 100%. As CTMs em cultivo são fibroblásticas, fusiformes, com citoplasma basofílico e núcleo esférico. O comprimento médio das células variou entre 80,85 e 98,36µm, a largura média entre 17,40 e 28,79µm e o diâmetro médio do núcleo entre 15,46 e 17,74µm.
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Fina, Emanuela, Carolina Reduzzi, Rosita Motta, Serena Di Cosimo, Giulia Bianchi, Antonia Martinetti, Janine Wechsler, Vera Cappelletti, and Maria G. Daidone. "Did Circulating Tumor Cells Tell us all they Could? The Missed Circulating Tumor Cell Message in Breast Cancer." International Journal of Biological Markers 30, no. 4 (October 2015): 429–33. http://dx.doi.org/10.5301/jbm.5000166.

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Purpose To compare circulating tumor cell (CTC) detection rates in patients with early (M0) and metastatic (M+) breast cancer using 2 positive-selection methods or size-based unbiased enrichment. Methods Blood collected at baseline and at different times during treatment from M0 patients undergoing neoadjuvant therapy and from M+ women starting a new line of treatment was processed in parallel using AdnaTest EMT-1/ and EMT-2/Stem CellSelect/Detect kits or ScreenCell Cyto devices. CTC positivity was defined according to the suggested cutoffs and cytological parameters, respectively. Results Higher CTC detection rates were obtained with the AdnaTest approach when using for CTC-enrichment antibodies against ERBB2 and EGFR in addition to MUC1 and the classical epithelial surface marker EPCAM (13% vs. 48%). In M0 patients mainly, CTC positivity rates further increased when EMT- and stemness-related marker expression (PIK3CA, AKT2 and ALDH1) was evaluated in addition to EPCAM, MUC1 and ERBB2. When the physical properties of tumor cells were exploited, CTCs were detected at higher percentages than with positive-selection-based methods, without any difference between clinical stages (78% in M0 vs. 72% in M+ cases at baseline). Circulating tumor microemboli (CTMs) were detected in addition to single CTCs with significantly higher frequency in M0 than M+ samples (78% vs. 27%, p = 0.0002). Conclusions Different approaches for CTC detection probably identify distinct tumor cell subpopulations, but need technical standardization before their clinical validity and biological specificity may be adequately investigated. The distinct role of CTMs compared with CTCs as prognostic and predictive biomarkers represents a further challenge.
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Reichert, Thaís, Rochelle Rocha Costa, Bruna Machado Barroso, Vitória de Mello Bones da Rocha, Henrique Bianchi Oliveira, Cláudia Gomes Bracht, Anemarí Girardon de Azevedo, and Luiz Fernando Martins Kruel. "Long-Term Effects of Three Water-Based Training Programs on Resting Blood Pressure in Older Women." Journal of Aging and Physical Activity 28, no. 6 (December 1, 2020): 962–70. http://dx.doi.org/10.1123/japa.2019-0236.

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The aim of the study was to compare the effects of three water-based training on blood pressure (BP) in older women. A total of 57 participants were randomized into the following groups: (a) aerobic training (AT), (b) concurrent training in which resistance training progresses to the use of resistive equipment (CTRE), and (c) concurrent training in which resistance training progresses to multiple sets (CTMS). The participants trained twice a week for 16 weeks. Systolic BP decreased from pretraining to after 8 weeks of training and, subsequently, to after 16 weeks of training (AT: −6.53 mmHg, CTRE: −10.45 mmHg, and CTMS: −10.73 mmHg). Diastolic BP decreased from pretraining to after 8 and 16 weeks of training (AT: −6.23 mmHg, CTRE: −4.61 mmHg, and CTMS: −6.19 mmHg). Furthermore, 16% of the AT participants, 23% of the CTRE participants, and 28.5% of the CTMS participants were no longer classified as hypertensive. Water-based aerobic and concurrent training are efficient nonpharmacological measures to reduce BP in older women.
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Oliveira, P. G. G., A. M. Carvalho, A. L. M. Yamada, L. Maia, N. P. P. Freitas, M. J. Watanabe, F. C. Landim-Alvarenga, and A. L. G. Alves. "Avaliação da migração das células progenitoras após terapia da tendinite equina." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 66, no. 4 (August 2014): 1033–38. http://dx.doi.org/10.1590/1678-6046.

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A terapia celular vem sendo utilizada com resultados promissores no tratamento da tendinite equina, entretanto ainda existem dúvidas quanto à persistência e ao comportamento dessas células quando implantadas no local da lesão, e quanto à sua migração para outros focos inflamatórios. O objetivo deste estudo foi avaliar a marcação das células-tronco mesenquimais (CTMs) com nanocristal antes e após o implante em lesões tendíneas experimentais do tendão flexor digital superficial (TFDS) de equinos, bem como observar a possibilidade de migração das CTMs marcadas para outro foco de lesão, o membro contralateral do mesmo animal. Para isso, foi realizada a indução de lesão experimental no TFDS em ambos os membros torácicos de cinco equinos e, após sete dias, foram implantadas as CTMs autólogas marcadas com o nanocristal Qtracker 655 em um dos membros dos animais. Após sete dias do implante, foi realizada a biópsia tendínea para posterior avaliação histopatológica, utilizando-se microscopia com fluorescência. Também foi realizado o teste de viabilidade celular antes e após a incubação com o nanocristal. As CTMs marcadas e injetadas no tecido tendíneo mantiveram sua fluorescência sete dias após seu implante, e não ocorreu migração para o membro contralateral. O uso do nanocristal para a marcação das CTMs derivadas da medula óssea equina mostrou-se efetivo pelo fato de essa nanopartícula não ter alterado a viabilidade celular e por ela ter permanecido ativa durante o período implantado.
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Magalhães, Geórgia M., Erika M. Terra, Sabryna G. Calazans, Rosemeri de O. Vasconcelos, and Antonio Carlos Alessi. "Avaliação da imunomarcação de células-tronco tumorais em carcinossarcomas mamários e carcinomas em tumores mistos em cadelas." Pesquisa Veterinária Brasileira 34, no. 5 (May 2014): 455–61. http://dx.doi.org/10.1590/s0100-736x2014000500012.

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As células-tronco tumorais (CTTs) pertencem a uma pequena população de células dentro do tumor com propriedades de autorrenovação e diferenciação em outros tipos celulares. Neste estudo avaliou-se o comportamento tanto das porções mesenquimais quanto das epiteliais de seis carcinossarcomas (CSs), 11 carcinomas em tumores mistos (CTMs) grau I, 11 grau II e 10 grau III. Nas porções epiteliais dos CS e CTM foram observadas imunomarcações para os anticorpos CD44, CD24, Oct-4 e ALDH-1. Nas porções mesenquimais dos CS, nas porções epiteliais dos CTMs graus II e III não houve imunomarcação para o ALDH-1. Concluiu-se que as CTTs são expressas em proporções iguais tanto nas porções mesenquimais quanto nas epiteliais dos CSs e ausentes nas porções mesenquimais bem diferenciadas de CTMs.
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Maia, Leandro, Fernanda C. Landim-Alvarenga, Márjorie de Assis Golim, Mateus José Sudano, Marilda O. Taffarel, Bruna De Vita, Natália Pereira P. Freitas, and Rogério M. Amorim. "Potencial de transdiferenciação neural das células-tronco mesenquimais da medula óssea de equino." Pesquisa Veterinária Brasileira 32, no. 5 (May 2012): 444–52. http://dx.doi.org/10.1590/s0100-736x2012000500013.

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Os primeiros estudos demonstrando o potencial de trandiferenciação neural das células-tronco mesenquimais (CTMs) provenientes da medula óssea (MO) foram conduzidos em camundogos e humanos no início da década de 2000. Após esse período, o número de pesquisas e publicações com o mesmo propósito tem aumentado, mas com raros ou escassos estudos na espécie equina. Nesse sentindo, o objetivo desse trabalho foi avaliar o potencial in vitro da transdiferenciação neural das CTMs provenientes da MO de equinos utilizando-se dois protocolos: P1 (forksolin e ácido retinóico) e P2 (2-βmecarptoetanol). Após a confirmação das linhagens mesenquimais, pela positividade para o marcador CD90 (X=97,94%), negatividade para o marcador CD34 e resposta positiva a diferenciação osteogênica, as CTMs foram submetidas a transdiferenciação neural (P1 e P2) para avaliação morfológica e expressão dos marcadores neurais GFAP e β3 tubulina por citometria de fluxo. Os resultados revelaram mudanças morfológicas em graus variados entre os protocolos testados. No protocolo 1, vinte quatro horas após a incubação com o meio de diferenciação neural, grande proporção de células (>80%) apresentaram morfologia semelhante a células neurais, caracterizadas por retração do corpo celular e grande número de projeções protoplasmáticas (filopodia). Por outro lado, de forma comparativa, já nos primeiros 30 minutos após a exposição ao antioxidante β-mercaptoetanol (P2) as CTMs apresentaram rápida mudança morfológica caracterizada principalmente por retração do corpo celular e menor número de projeções protoplasmáticas. Também ficou evidenciado com o uso deste protocolo, menor aderência das células após tempo de exposição ao meio de diferenciação, quando comparado ao P1. Com relação a análise imunofenotípica foi observado uma maior (P<0,001) expressão dos marcadores GFAP e β3 tubulina ao término do P2 quando comparado ao P1. A habilidade das CTMs em gerar tipos celulares relacionados a linhagem neural é complexa e multifatorial, dependendo não só dos agentes indutores, mas também do ambiente no qual estas células são cultivadas. Desta forma um maior número de estudos é necessário para o melhor entendimento do processo de transdiferenciação neural a partir de CTMs de equinos.
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Kulasinghe, Arutha, Jian Zhou, Liz Kenny, Ian Papautsky, and Chamindie Punyadeera. "Capture of Circulating Tumour Cell Clusters Using Straight Microfluidic Chips." Cancers 11, no. 1 (January 14, 2019): 89. http://dx.doi.org/10.3390/cancers11010089.

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Circulating tumour cells (CTCs) are the metastatic precursors to distant disease in head and neck cancers (HNCs). Whilst the prognostic and predictive value of single CTCs have been well documented, the role of CTC clusters, which potentially have a higher metastatic capacity are limited. In this study, the authors used a novel straight microfluidic chip to focus and capture CTCs. The chip offers high cell recoveries with clinically relevant numbers (10–500 cells/mL) without the need for further purification. Single CTCs were identified in 10/21 patient samples (range 2–24 CTCs/mL), CTC clusters in 9/21 patient samples (range 1–6 CTC clusters/mL) and circulating tumour microemboli (CTM) in 2/21 samples. This study demonstrated that CTC clusters contain EGFR amplified single CTCs within the cluster volume. This novel microfluidic chip demonstrates the efficient sorting and preservation of single CTCs, CTC clusters and CTMs. The authors intend to expand this study to a larger cohort to determine the clinical implication of the CTC subsets in HNC.
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Dissertations / Theses on the topic "CTMs"

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Mugodo, James, and n/a. "Plant species rarity and data restriction influence the prediction success of species distribution models." University of Canberra. Resource, Environmental & Heritage Sciences, 2002. http://erl.canberra.edu.au./public/adt-AUC20050530.112801.

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There is a growing need for accurate distribution data for both common and rare plant species for conservation planning and ecological research purposes. A database of more than 500 observations for nine tree species with different ecological and geographical distributions and a range of frequencies of occurrence in south-eastern New South Wales (Australia) was used to compare the predictive performance of logistic regression models, generalised additive models (GAMs) and classification tree models (CTMs) using different data restriction regimes and several model-building strategies. Environmental variables (mean annual rainfall, mean summer rainfall, mean winter rainfall, mean annual temperature, mean maximum summer temperature, mean minimum winter temperature, mean daily radiation, mean daily summer radiation, mean daily June radiation, lithology and topography) were used to model the distribution of each of the plant species in the study area. Model predictive performance was measured as the area under the curve of a receiver operating characteristic (ROC) plot. The initial predictive performance of logistic regression models and generalised additive models (GAMs) using unrestricted, temperature restricted, major gradient restricted and climatic domain restricted data gave results that were contrary to current practice in species distribution modelling. Although climatic domain restriction has been used in other studies, it was found to produce models that had the lowest predictive performance. The performance of domain restricted models was significantly (p = 0.007) inferior to the performance of major gradient restricted models when the predictions of the models were confined to the climatic domain of the species. Furthermore, the effect of data restriction on model predictive performance was found to depend on the species as shown by a significant interaction between species and data restriction treatment (p = 0.013). As found in other studies however, the predictive performance of GAM was significantly (p = 0.003) better than that of logistic regression. The superiority of GAM over logistic regression was unaffected by different data restriction regimes and was not significantly different within species. The logistic regression models used in the initial performance comparisons were based on models developed using the forward selection procedure in a rigorous-fitting model-building framework that was designed to produce parsimonious models. The rigorous-fitting modelbuilding framework involved testing for the significant reduction in model deviance (p = 0.05) and significance of the parameter estimates (p = 0.05). The size of the parameter estimates and their standard errors were inspected because large estimates and/or standard errors are an indication of model degradation from overfilling or effecls such as mullicollinearily. For additional variables to be included in a model, they had to contribule significantly (p = 0.025) to the model prediclive performance. An attempt to improve the performance of species distribution models using logistic regression models in a rigorousfitting model-building framework, the backward elimination procedure was employed for model selection, bul it yielded models with reduced performance. A liberal-filling model-building framework that used significant model deviance reduction at p = 0.05 (low significance models) and 0.00001 (high significance models) levels as the major criterion for variable selection was employed for the development of logistic regression models using the forward selection and backward elimination procedures. Liberal filling yielded models that had a significantly greater predictive performance than the rigorous-fitting logistic regression models (p = 0.0006). The predictive performance of the former models was comparable to that of GAM and classification tree models (CTMs). The low significance liberal-filling models had a much larger number of variables than the high significance liberal-fitting models, but with no significant increase in predictive performance. To develop liberal-filling CTMs, the tree shrinking program in S-PLUS was used to produce a number of trees of differenl sizes (subtrees) by optimally reducing the size of a full CTM for a given species. The 10-fold cross-validated model deviance for the subtrees was plotted against the size of the subtree as a means of selecting an appropriate tree size. In contrast to liberal-fitting logistic regression, liberal-fitting CTMs had poor predictive performance. Species geographical range and species prevalence within the study area were used to categorise the tree species into different distributional forms. These were then used, to compare the effect of plant species rarity on the predictive performance of logistic regression models, GAMs and CTMs. The distributional forms included restricted and rare (RR) species (Eucalyptus paliformis and Eucalyptus kybeanensis), restricted and common (RC) species (Eucalyptus delegatensis, Eucryphia moorei and Eucalyptus fraxinoides), widespread and rare (WR) species (Eucalyptus data) and widespread and common (WC) species (Eucalyptus sieberi, Eucalyptus pauciflora and Eucalyptus fastigata). There were significant differences (p = 0.076) in predictive performance among the distributional forms for the logistic regression and GAM. The predictive performance for the WR distributional form was significantly lower than the performance for the other plant species distributional forms. The predictive performance for the RC and RR distributional forms was significantly greater than the performance for the WC distributional form. The trend in model predictive performance among plant species distributional forms was similar for CTMs except that the CTMs had poor predictive performance for the RR distributional form. This study shows the importance of data restriction to model predictive performance with major gradient data restriction being recommended for consistently high performance. Given the appropriate model selection strategy, logistic regression, GAM and CTM have similar predictive performance. Logistic regression requires a high significance liberal-fitting strategy to both maximise its predictive performance and to select a relatively small model that could be useful for framing future ecological hypotheses about the distribution of individual plant species. The results for the modelling of plant species for conservation purposes were encouraging since logistic regression and GAM performed well for the restricted and rare species, which are usually of greater conservation concern.
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Lee, SeungYong Albert 1975. "Object modeling applied to CTAS." Thesis, Massachusetts Institute of Technology, 1999. http://hdl.handle.net/1721.1/80098.

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Thesis (S.B. and M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1999.
Includes bibliographical references (leaf 49).
by Seung Yong Albert Lee.
S.B.and M.Eng.
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Brage, Carl, Simon Hadenius, Daniel Johansson, Billy Krig, Simon Lindblad, Emil Nilsson, Joacim Stålberg, and Mattias Ulmstedt. "Snowy : Visualisering av SNOMED CT:s data." Thesis, Linköpings universitet, Institutionen för datavetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-129333.

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Detta dokument beskriver ett kandidatexamensarbete som genomförts av åtta civilingenjörsstudenter från Linköpings universitet. Examensarbetet bestod av att utveckla en webbapplikation för att möjliggöra navigation och visualisering av element ur den medicinska databasen SNOMED CT samt deras relationer. Den första delen av dokumentet består av gruppens gemensamma arbete och erfarenheter för att uppfylla kundens givna krav samt själva processen om hur det är att arbeta i ett större mjukvaruprojekt. Den andra delen består av studenternas individuella bidrag till examensarbetet som berör något spridda ämnen men som har en anknytning till mjukvaruutveckling och projektarbete.
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Wong, San San. "The study of the competitiveness of CTM : based on CTM branding strategy." Thesis, University of Macau, 2009. http://umaclib3.umac.mo/record=b2147585.

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Koepsel, Raica. "CTS no ensino médio." Florianópolis, SC, 2003. http://repositorio.ufsc.br/xmlui/handle/123456789/84764.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Educação. Programa de Pós-Graduação em Educação.
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Esta dissertação busca discutir, através de pesquisa bibliográfica, as possibilidades para inserção de CTS (Ciência, Tecnologia e Sociedade) no Ensino Médio brasileiro. Tem por objetivo contribuir com a educação no sentido de aproximá-la mais da realidade, do cotidiano, do aluno tornando-a, assim, mais significativa e interessante. Esta inserção é exemplificada utilizando-se utilizando-se a disciplina de Química (tema Radioatividade) como exemplo. Palavras Chave : CTS, Ensino Médio, Ensino de Química, Radioatividade
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Figueira, Joyce Cardoso. "ctos familiares e o processo de alfabetização." Universidade do Estado de Santa Catarina, 2002. http://tede.udesc.br/handle/handle/2173.

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A presente dissertação tem como objetivo correlacionar aspectos de vivência familiar com o processo de alfabetização vividos pelas crianças de cinco a sete anos. Buscou-se enfatizar os aspectos familiares do processo, que embora apontados pela bibliografia através de diversos autores, na prática encontram-se longe de serem experenciados, fazendo com que seja observada uma lacuna entre família e escola. Foram utilizados como referencial teórico os autores Jean Piaget, Lev Vygostsky e Emília Ferreiro, no que concerne às questões específicas da alfabetização. Com relação ao aspecto familiar, lançou-se mão do pensamento sistêmico. Como os primeiros anos de vida são essenciais para o desenvolvimento humano, e como neste período a família possui especial significado para o indivíduo, colocou-se em evidência a importância do envolvimento do sistema familiar no processo de alfabetização infantil.
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Qian, Xingsheng. "Modelling and dynamic simulation of a CTMP plant." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq25140.pdf.

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Jahanmir, Farid. "Failure detection and repair of threads in CTAS." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/33134.

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Thesis (M. Eng. and S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004.
Includes bibliographical references (p. 73).
Reliable, error-free software is hard to come by, and this is especially true for newer, larger, or more complex programs. CTAS, an air traffic control tool, falls into this category, making it a good candidate for research on error compensation. Specifically, this thesis addresses the issue of thread crashes in one portion of CTAS. We reimplement the thread structure in question around a simpler problem, and develop a failure detector and an accompanying repair mechanism to monitor it. These add-on components provide the application with thread consistency by swiftly and transparently recovering from crashes, thereby yielding a more stable, self-sufficient, and generally more reliable operating environment.
by Farid Jahanmir.
M.Eng.and S.B.
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Kykal, Roman. "Ocenění CTS-servis, spol. s.r.o." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-16709.

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Mission of thesis is to provide theoretical foundations of business evaluation and work out an appraiser opinion. Object of appraisal is CTS-servis, private limited company, that was sold in 2008. Resulting value of the appraisal is finally compared with the price that was realised. Technique of evaluation process stem from methodology that is contained in publication "Bussines evaluation methods" from Prof. M. Marik. Main method that is used to evaluate the company is DCF equity.
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Qing, Shuping 1969. "Optimal control for a CTMP process with simulated annealing." Thesis, McGill University, 1999. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=30270.

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In this thesis, a problem of optimal control for a CTMP(chemi-thermo-mechanical pulping) process is formulated and solved by applying simulated annealing algorithm.
Based on priori knowledge accumulated from years of practical operations, a set of imprecise and empirical equations are derived to give a description of a CTMP process. The system dynamics which is a key actor in this process control is also presented and analyzed. Due to the imprecise and highly nonlinear characteristic of this system, the need for a proper global optimization algorithm is highlighted.
The application of the simulated annealing algorithm is explored in cases of both the mainline and the whole process control. Comparisons of this method with some other optimization methods are characterized in general in terms of feasibility and accuracy. It is shown from experiments that although it is a time consuming algorithm, simulated annealing is suitable for decision making of process manipulations aiming at maximizing profit.
Finally, a PI feedback loop is implemented to fulfill this control scheme of the process. Then, with critical system disturbances and high degree process variance under control, an optimal control law is synthesized for the set-point tracking control policies. The controller performance is investigated at the simulation level.
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Books on the topic "CTMs"

1

Tavernini, Lucio. Continuous-time modeling and simulation: Using Turbo Pascal and CTMS/TP. Amsterdam: Gordon and Breach, 1996.

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Miller, Edna Ilyin. Exploring CTOS. Englewood Cliffs, N.J: Prentice Hall, 1991.

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Stanley, Siegel, Donaldson Gary, and SpringerLink (Online service), eds. CTOs at Work. Berkeley, CA: Apress, 2012.

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Donaldson, Scott, Stanley Siegel, and Gary Donaldson. CTOs at Work. Berkeley, CA: Apress, 2012. http://dx.doi.org/10.1007/978-1-4302-3594-1.

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México, Confederación de Trabajadores de. Constitución CTM. México: Secretaría del Trabajo y Previsión Social, Subsecretaría "B", Unidad Coordinadora de Políticas, Estudios y Estadísticas del Tabajo, 1987.

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Neuman, Frank. CTAS data analysis program. Moffett Field, Calif: National Aeronautics and Space Administration, Ames Research Center, 1994.

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Limkemann, William O. Application programming in CTOS. Englewood Cliffs, N.J: PTR Prentice Hall, 1993.

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International Cotton Advisory Committee. Secretariat. CTM: Cotton trading manual. Boca Raton: CRC Press, 2005.

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Nassif, Alberto Aziz. Estado mexicano y la CTM. Mexico, D.F: Ediciones de la Casa Chata, 1989.

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Jones, Ruth. Post-16 provision in CTCs: Bridging the divide. London: City Technology Colleges Trust, 1992.

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Book chapters on the topic "CTMs"

1

Bieser, Johannes, Martin Otto Paul Ramacher, Marje Prank, Efisio Solazzo, and Andreas Uppstu. "Multi Model Study on the Impact of Emissions on CTMs." In Springer Proceedings in Complexity, 309–15. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-22055-6_49.

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Donaldson, Scott, Stanley Siegel, and Gary Donaldson. "Amy Alving." In CTOs at Work, 1–20. Berkeley, CA: Apress, 2011. http://dx.doi.org/10.1007/978-1-4302-3594-1_1.

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Donaldson, Scott, Stanley Siegel, and Gary Donaldson. "Jan-Erik de Boer." In CTOs at Work, 219–37. Berkeley, CA: Apress, 2011. http://dx.doi.org/10.1007/978-1-4302-3594-1_10.

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Donaldson, Scott, Stanley Siegel, and Gary Donaldson. "Paul Bloore." In CTOs at Work, 239–60. Berkeley, CA: Apress, 2011. http://dx.doi.org/10.1007/978-1-4302-3594-1_11.

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Donaldson, Scott, Stanley Siegel, and Gary Donaldson. "William Ballard." In CTOs at Work, 261–83. Berkeley, CA: Apress, 2011. http://dx.doi.org/10.1007/978-1-4302-3594-1_12.

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Donaldson, Scott, Stanley Siegel, and Gary Donaldson. "David Kuttler." In CTOs at Work, 285–305. Berkeley, CA: Apress, 2011. http://dx.doi.org/10.1007/978-1-4302-3594-1_13.

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Donaldson, Scott, Stanley Siegel, and Gary Donaldson. "Don Ferguson." In CTOs at Work, 21–47. Berkeley, CA: Apress, 2011. http://dx.doi.org/10.1007/978-1-4302-3594-1_2.

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Donaldson, Scott, Stanley Siegel, and Gary Donaldson. "Craig Miller." In CTOs at Work, 49–79. Berkeley, CA: Apress, 2011. http://dx.doi.org/10.1007/978-1-4302-3594-1_3.

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Donaldson, Scott, Stanley Siegel, and Gary Donaldson. "Jerry Krill." In CTOs at Work, 81–104. Berkeley, CA: Apress, 2011. http://dx.doi.org/10.1007/978-1-4302-3594-1_4.

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Donaldson, Scott, Stanley Siegel, and Gary Donaldson. "Wesley Kaplow." In CTOs at Work, 105–26. Berkeley, CA: Apress, 2011. http://dx.doi.org/10.1007/978-1-4302-3594-1_5.

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Conference papers on the topic "CTMs"

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Codecasa, Lorenzo, Vincenzo d'Alessandro, and Dario D'Amore. "Altering MOR-based BCI CTMs into Delphi-like BCI CTMs." In 2020 26th International Workshop on Thermal Investigations of ICs and Systems (THERMINIC). IEEE, 2020. http://dx.doi.org/10.1109/therminic49743.2020.9420528.

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Smith, J. Cole, Alfonso Ortega, Colleen M. Gabel, and Dale Henderson. "Parameter Optimization for a Temperature Estimation Model." In ASME 2003 International Electronic Packaging Technical Conference and Exhibition. ASMEDC, 2003. http://dx.doi.org/10.1115/ipack2003-35254.

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We consider a problem arising in designing Compact Thermal Models (CTMs) for the purpose of simulating the thermal response of a package. CTMs are often preferred over more detailed models due to their minimal representation and the reduced computations required to obtain accurate nodal temperature predictions under hypothetical scenarios. The quality of CTM performance depends on the determination of an appropriate set of parameters that drive the model. The subject of this paper is a heuristic nonlinear optimization approach to computing the set of CTM parameters that best predicts the thermal response of a package. Our algorithm solves a series of one-dimensional nonconvex optimization problems to obtain these parameters, exploiting the special structure of the CTM in order to improve both the execution time of the algorithm and the quality of the CTM performance. We conclude the paper by providing a brief array of computational results as a proof of concept, along with several possible future research extensions.
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Greisen, D. H., and V. P. Manno. "Nodal Topology in Compact Thermal Models." In ASME 2007 InterPACK Conference collocated with the ASME/JSME 2007 Thermal Engineering Heat Transfer Summer Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/ipack2007-33425.

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Compact Thermal Models (CTMs) utilize a few connected thermal nodes to represent the thermal characteristics of electronic packages. These models are preferable to highly discretized models in preliminary design and system level analysis because of their computational efficiency. Surface heat flux non-uniformities often make it necessary to subdivide the package surfaces into multiple CTM nodes. This division is often quantified as the surface area ratio. This work assesses CTM performance sensitivity to area ratio changes and variation in heat transfer coefficient boundary conditions. CTMs for benchmark TQFP and BGA packages are developed using an admittance matrix approach. While optimum area ratios are identified, a direct correlation between these optimal values and the heat flux distributions computed from fully-discretized models was not obtained. CTM performance was found to be sensitive to changes in the heat transfer coefficient used to generate the CTM parameter values. A critical generating heat transfer coefficient was determined such that the resulting CTM, when optimized for a single boundary condition, was relatively accurate over the whole set of boundary conditions considered. This single boundary condition also provided an upper bound for error. This finding could be significant in future CTM development procedures.
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Gupta, Rohit Dev, and Vinayak Eswaran. "Numerical Solution Methodology for Compact Thermal Models of Electronic Packages." In ASME/JSME 2007 Thermal Engineering Heat Transfer Summer Conference collocated with the ASME 2007 InterPACK Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/ht2007-32139.

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Compact Thermal Models (CTMs) are multi-nodal thermal resistor networks which predict the internal thermal response of an electronic package, in various environments, to within an accuracy of 2%. The junction temperature of the package is typically obtained by solving a set of linear algebraic equations wherein the heat transfer to the ambience is modeled by a convection coefficient obtained from hand-book data, assuming identical ambient conditions imposed at all nodal surfaces. In reality, this approach may give misleading results as the ambience at each of the nodal surfaces is different and depends on the cooling fluid flow behavior at that surface. In this work, a methodology is presented where the network equations of the CTMs are coupled with the governing fluid equations solved by computational fluid dynamics (CFD). The CTM+CFD approach predicts a significantly (28%) higher junction temperature as compared to the conventional CTM network solver method, even when the convection coefficient used in the latter is obtained more accurately from CFD, rather than from hand-book correlations. It is likely that the new approach offers a more effective prediction of the package thermal performance.
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Peterchev, Angel V., David L. Murphy, and Sarah H. Lisanby. "Repetitive transcranial magnetic stimulator with controllable pulse parameters (cTMS)." In 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2010). IEEE, 2010. http://dx.doi.org/10.1109/iembs.2010.5626287.

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Chen, Xiqun, Li Li, Qixin Shi, and Jin-Xin Cao. "Equilibrium analysis and comparison for general CTMs and LCTMs." In 2010 13th International IEEE Conference on Intelligent Transportation Systems - (ITSC 2010). IEEE, 2010. http://dx.doi.org/10.1109/itsc.2010.5625126.

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Burgess, B. A., T. Clayton, A. Boday, and J. Krimm. "Development of a Cable Test Management System (CTMS) Application." In SNAME Maritime Convention. SNAME, 2013. http://dx.doi.org/10.5957/smc-2013-p32.

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The Test & Trials Department at HII-Ingalls Shipbuilding is responsible for testing specified electrical cables installed on ships under construction at Ingalls Shipbuilding. These tests are conducted on ships which can have tens of thousands of cables pulled, thus HII-Ingalls Shipbuilding personnel must manage a large amount of cable business data. The various tests are performed by skilled Test Conductors using a largely manual, paper-based process to gather and manage the test data. Test & Trials Department personnel maintain these datasets and associate specific Test Procedures to ship equipment operating requirements by cable or circuit type. CTMS required developing two way communications: 1) Between the CN3 mobile device and a windows computer with an Access database containing specific cable information and used as a repository for the actual test results and 2) Between the CN3 mobile device and the test equipment to pass specific test criteria to the test equipment and the test conductor and to capture the actual results. Custom device drivers were written to allow direct serial communication between the Intermec CN3 handheld computer and the Anritsu Site Master™ S820D Analyzer. This setup allowed the team to meet the goals of the project; leveraging existing devices to improve data reliability and expose new potential for process improvement in the cable test environment.
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Ben Abderrahim, Oumaima, Mohamed Houcine Elhedhili, and Leila Saidane. "CTMS-SIOT: A context-based trust management system for the social Internet of Things." In 2017 13th International Wireless Communications and Mobile Computing Conference (IWCMC). IEEE, 2017. http://dx.doi.org/10.1109/iwcmc.2017.7986574.

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Miz, Volodymyr, and Vladimir Hahanov. "Smart traffic light in terms of the cognitive road traffic management system (CTMS) based on the Internet of Things." In 2014 East-West Design & Test Symposium (EWDTS). IEEE, 2014. http://dx.doi.org/10.1109/ewdts.2014.7027102.

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McDonald, Jon P., and Arthur M. Mellor. "Design of Inlet Conditions for High Pressure NOx Measurements in Lean Premixed Combustors." In ASME 1995 International Gas Turbine and Aeroengine Congress and Exposition. American Society of Mechanical Engineers, 1995. http://dx.doi.org/10.1115/95-gt-136.

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Semi–empirical characteristic time models (CTMs) for NOx emissions index (EI) and lean blowoff are used in the design of an inlet condition matrix for measurement of NOxEI from a lean premixed combustor. Such models relate either NOxEI or the weak extinction limit to times representing relevant physical and chemical processes in the combustor. Lean premixed (LP) natural gas/air combustion is considered for the following conditions: inlet temperature, 300–800 K; combustor pressure, 1–30 atm; and equivalence ratio, 0.5–0.7. The NOx model is used to determine combinations of inlet conditions corresponding to greatest NOx sensitivity. A dependence of NOx emissions on pressure is included in the model. Emissions of oxides of nitrogen are found to he most sensitive to variations in inlet temperature and combustor pressure, in the 560–800 K and 20–30 atm ranges, respectively, while sensitivity to variations in equivalence ratio is substantial over the entire range considered. Thus it is found that operating conditions for high thermal efficiency in LP turbine combustors conflict with the goal of lowering NOx emissions, a result consistent with thermal NOx from conventional, diffusion flame combustors. A lean blowoff model is used to estimate the lowest equivalence ratio at which a flame can he held, as well as to determine whether a flame can be stabilised at the operating conditions suggested by the NOx sensitivity analysis. The results suggest a nominal lower limit on equivalence ratio of 0.4, and that a flame can be held for most of the combinations of inlet conditions suggested by the NOx sensitivity analysis. Autoignition of the fuel/air mixture is also considered in relation to the location and/or design of the premixing system. The current NOx CTM is applied to LP natural gas fired data from the literature. A model modification, thought to better represent the fluid mechanics relevant to LP NOx formation, is applied, and its implications discussed.
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Reports on the topic "CTMs"

1

Sheaffer, K., T. Porter, H. Jones, T. Jefferson, T. Cody, D. Gomes, J. Hutchins, D. Derby, T. Faulkner, and R. Mines. CTSS to UNICOS migration plan. Office of Scientific and Technical Information (OSTI), November 1989. http://dx.doi.org/10.2172/5291682.

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2

Bundy, Dave. Combat Trauma Patient Simulation (CTPS) Program. Fort Belvoir, VA: Defense Technical Information Center, November 2001. http://dx.doi.org/10.21236/ada400337.

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Brown, Michael R. Novel CT's Equilibrium, Stability, and Dynamics. Office of Scientific and Technical Information (OSTI), February 2011. http://dx.doi.org/10.2172/1006408.

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Leininger, Matt. Level-2 Milestone 5213. CTS-1 Contract Award Completed. Office of Scientific and Technical Information (OSTI), September 2015. http://dx.doi.org/10.2172/1237561.

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Leininger, M. Level 2 Milestone 4795: CTS-1 Market Survey Completed. Office of Scientific and Technical Information (OSTI), June 2014. http://dx.doi.org/10.2172/1162262.

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Thomas, Shari R. Review of Personnel Susceptibility to Lasers: Simulation in SIMNET-D for CTAS-2.0. Fort Belvoir, VA: Defense Technical Information Center, January 1995. http://dx.doi.org/10.21236/ada293827.

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Rodgers, Arthur J., N. Anders Petersson, Arben Pitarka, and Bjorn Sjogreen. Running SW4 On New Commodity Technology Systems (CTS-1) Platform. Office of Scientific and Technical Information (OSTI), August 2016. http://dx.doi.org/10.2172/1321435.

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Rasche, Jeanette. Test and Evaluation of a Networked Patient Simulator System: Combat Trauma Patient Simulator (CTPS). Fort Belvoir, VA: Defense Technical Information Center, January 2002. http://dx.doi.org/10.21236/ada399914.

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9

Baldwin, R., and R. Rivest. The RC5, RC5-CBC, RC5-CBC-Pad, and RC5-CTS Algorithms. RFC Editor, October 1996. http://dx.doi.org/10.17487/rfc2040.

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Mandelbaum, Jay. Identifying and Assessing Life-Cycle-Related Critical Technology Elements (CTEs) for Technology Readiness Assessments (TRAs). Fort Belvoir, VA: Defense Technical Information Center, November 2006. http://dx.doi.org/10.21236/ada465212.

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