Academic literature on the topic 'Cryopreserved homograft'

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Journal articles on the topic "Cryopreserved homograft"

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Mestres, Carlos-A., Ramón Cartaña, Manuel Castella, Jaime Mulet, and José L. Pomar. "Ascending Aorta to Femoral Bypass with Cryopreserved Vascular Homografts." Asian Cardiovascular and Thoracic Annals 3, no. 2 (June 1995): 90–92. http://dx.doi.org/10.1177/021849239500300216.

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Homograft vascular replacement is almost as old as vascular surgery itself. Gross and Dubost are credited as the first authors who clinically attempted vascular reconstruction using biological tissue of human origin. The advent of synthetic vascular prostheses together with the complexity of logistics in procuring, preserving, and storing vascular homografts made the routine use of vascular homografts impractical. Cryopreservation techniques have strongly influenced the use of biological tissue. The tireless work of a few authors has enabled us to better understand the behavior of homograft tissues in cardiovascular surgery. Homograft replacement of the aortic and pulmonary valves is now a recognized way to treat a number of conditions of the aortic root and the right ventricular outflow tract. Renewed interest in the use of cryopreserved homografts in cardiac surgery has led us to expand our own indications for their use. As our Cryopreservation Unit is fully operative, we also have vascular homografts available for implantation. Here we describe the extended use of vascular homografts in extraanatomic aortic bifurcation bypass in a patient with previous multiple vascular operations. To use the ascending aorta as the inflow source in cardiovascular reconstruction has been previously described; however, it has not been popular among surgeons. Robicsek termed this type of bypass graft “very long” aortic grafts, and we recently had the chance to use fully biological tissue of human origin for this type of reconstruction.
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Bisdas, Mattner, Ott, Pichlmaier, Wilhelmi, Haverich, and Teebken. "Significance of infection markers and microbiological findings during tissue processing of cryopreserved arterial homografts for the early postoperative course." Vasa 38, no. 4 (November 1, 2009): 365–73. http://dx.doi.org/10.1024/0301-1526.38.4.365.

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Background: To evaluate homograft implantation for the urgent treatment of vascular infections on the basis of the course of infection using microbiological findings in perioperatively obtained specimens and during homograft processing. Patients and methods: 85 patients were treated with cryopreserved homografts from 2004-2007. The microbiological findings of the decontamination process of homografts in the tissue bank were evaluated. The perioperative infection profile (microorganisms, CRP, leukocytes, body temperature) of the patients was analysed. Results: Complete microbiological and clinical follow-up for the postoperative course was available for 35 patients, who were treated with homografts from the same tissue bank and finally included into this study. 55 cryopreserved homografts were implanted. 35 / 55 (64 %) homografts were positive for microorganisms before decontamination. 3 / 35 (9 %) homografts remained positive after the decontamination. 33 patients were operated for prosthetic graft infection and 2 for an infiltration of a large vessel from neighbouring malignant disease. The most common infection agent was Staphylococcus aureus. Thirty-day mortality was 20 % (7 / 35). Only in 4 / 35 (11 %) patients were the microorganisms of the intraoperative swabs also detected during the postoperative course. The microorganisms were ORSA, Enterococcus faecium, Enterobacter aerogenes and Burkholderia cepacia. The patient with ORSA infection died on POD 11 from multiple organ failure and all other patients recovered. None of the postoperative swabs showed the homograft predecontamination microorganisms. Interestingly, a significant association (P = 0.003) between C-reactive protein increase two weeks after surgery and donor-recipient ABO mismatch was found. Conclusions: The implantation of homografts following the established decontamination is an alternative urgent therapeutic option in vascular infections with encouraging outcomes. The absence of the predecontamination focus in the postoperative specimens of patients, suggests that the postoperative course and outcomes show no strong relation to potential homograft contamination prior to the decontamination process.
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Almassi, G. Hossein. "Cryopreserved Pulmonary Homograft." Journal of Cardiac Surgery 7, no. 2 (June 1992): 192. http://dx.doi.org/10.1111/j.1540-8191.1992.tb00798.x.

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Butany, Jagdish, Manmeet S. Ahluwalia, Vidhya Nair, and Tirone E. David. "Cryopreserved pulmonary homograft." Cardiovascular Pathology 13, no. 1 (January 2004): 59–61. http://dx.doi.org/10.1016/s1054-8807(03)00092-9.

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Schroeder, Meierling, Riepe, Braun, and Imig. "Behandlung einer aortobifemoralen Protheseninfektion durch Rekonstruktion mit kryokonservierten homologen Arterien aus der European Homograft Bank." Vasa 28, no. 1 (February 1, 1999): 42–45. http://dx.doi.org/10.1024/0301-1526.28.1.42.

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The excision of an infected aortobifemoral Dacron graft 9 years after implantation and bilateral axillofemoral Dacron bypass reconstruction led to reinfection of the extra-anatomic bypass grafts. A new aorto-bifemoral reconstruction was performed using cryopreserved homografts delivered by the European Homograft Bank in Brussels and both axillo-femoral prostheses were removed. No signs of infection and no alterations of the homografts can be detected 3 years later.
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Tan, Christian H., David C. Cleveland, Robert J. Dabal, Luz A. Padilla, Kathryn S. Maxwell, Mark A. Law, Waldemar F. Carlo, Santiago Borasino, and Robert A. Sorabella. "Association Between Venous Homografts and Allosensitization After Norwood Procedure." World Journal for Pediatric and Congenital Heart Surgery 14, no. 1 (January 2023): 25–30. http://dx.doi.org/10.1177/21501351221120411.

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Background Right ventricle (RV) to pulmonary artery (PA) shunts have become the shunt of choice at many centers for use during the Norwood procedure for single ventricle palliation. Some centers have begun to use cryopreserved femoral or saphenous venous homografts as an alternative to polytetrafluoroethylene (PTFE) for shunt construction. The immunogenicity of these homografts is unknown, and potential allosensitization could have significant implications on transplant candidacy. Methods All patients undergoing Glenn procedure at our center between 2013 and 2020 were screened. Patients who initially underwent Norwood procedure with either PTFE or venous homograft RV-PA shunt and had available pre-Glenn serum were included in the study. The primary outcome of interest was panel reactive antibody (PRA) level at the time of Glenn surgery. Results Thirty-six patients met inclusion criteria (N = 28 PTFE, N = 8 homograft). Patients in the homograft group had significantly higher median PRA levels at the time of Glenn surgery (0% [IQR 0-18] PTFE vs 94% [IQR 74-100] homograft, P = .003). There were no other differences between the two groups. Conclusions Despite potential improvements in PA architecture, the use of venous homografts for RV-PA shunt construction at the time of Norwood procedure is associated with significantly elevated PRA level at the time of Glenn surgery. Centers should carefully consider the use of currently available venous homografts given the high percentage of these patients who may require future transplantation.
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Yanagawa, Bobby, Amine Mazine, Derrick Y. Tam, Peter Jüni, Deepak L. Bhatt, Stephen Spindel, John D. Puskas, Subodh Verma, and Jan O. Friedrich. "Homograft versus Conventional Prosthesis for Surgical Management of Aortic Valve Infective Endocarditis." Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery 13, no. 3 (May 2018): 163–70. http://dx.doi.org/10.1097/imi.0000000000000510.

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Objective Surgical management of aortic valve infective endocarditis (IE) with cryopreserved homograft has been associated with lower risk of recurrent IE, but there is equipoise with regard to the optimal prosthesis. This systematic review and meta-analysis were performed to compare outcomes between homograft and conventional prosthesis for aortic valve IE. Methods We searched MEDLINE database to September 2017 for studies comparing homograft versus conventional prosthesis. The main outcomes were all-cause mortality, recurrent IE, and reoperation. Results There were 18 included comparative observational studies with 2232 patients (median follow up = 5 [interquartile range: 2–7] years, 30% prosthetic valve endocarditis); four studies were adjusted for baseline differences. There were no differences in perioperative mortality or stroke despite a greater proportion of staphylococcal endocarditis, abscess, and root replacements but less multivalve involvement in the homograft group. Long-term outcomes of all-cause mortality [incidence rate ratio (IRR) = 1.03, 95% confidence interval (CI) = 0.81–1.31, P = 0.83, for unmatched, and IRR = 0.82, 95% CI = 0.36–1.84, P = 0.63, for matched studies], recurrent endocarditis (IRR = 1.01, 95% CI = 0.53–1.93, P = 0.96, for unmatched, and IRR = 1.04, 95% CI = 0.49–2.19, P = 0.92, for matched studies), and reoperation (IRR = 1.60, 95% CI = 0.80–3.21, P = 0.18, for unmatched, and IRR = 3.17, 95% CI = 0.52–19.44, P = 0.21, for matched studies) were not different comparing homograft versus conventional prosthesis. There was a significantly increased need for reoperation with homograft versus mechanical prosthetic valves, but this comparison was based on limited data. Conclusions Homografts and conventional prostheses offer similar survival and freedom from recurrent endocarditis and reoperation for aortic valve IE. Homografts may be associated with greater risk of reoperation compared with mechanical valves.
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Motomura, N. "A study of cryopreserved human homograft." Japanese Journal of Cardiovascular Surgery 19, no. 6 (1990): 1307–9. http://dx.doi.org/10.4326/jjcvs.19.1307.

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Vogt, Paul, Miralem Pasic, Ludwig von Segesser, Thierry Carrel, and Marko Turina. "Cryopreserved aortic homograft for mycotic aneurysm." Journal of Thoracic and Cardiovascular Surgery 109, no. 3 (March 1995): 589–91. http://dx.doi.org/10.1016/s0022-5223(95)70294-6.

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Barili, Fabio, Luca Dainese, Anna Guarino, Paolo Biglioli, and Gianluca Polvani. "The Challenge of Homograft Tissue Banks: The Viability of Cryopreserved Valvular Homografts." Journal of Heart and Lung Transplantation 26, no. 9 (September 2007): 964–65. http://dx.doi.org/10.1016/j.healun.2007.07.005.

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Dissertations / Theses on the topic "Cryopreserved homograft"

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Chan, Chun-wai. "In-vitro study of the cryopreserved intervertebral disc." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41290380.

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Yap, Cheng-Hon. "Factors influencing cryopreserved allograft heart valve degeneration." Connect to thesis, 2006. http://repository.unimelb.edu.au/10187/2120.

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Heart valve replacement is becoming more commonplace in developed nations. Despite this the ideal valve prosthesis has not been found. The allograft valve has been used for over 40 years and remains an important prosthesis with many advantages. However, like other biological valve prosthesis, they have a finite durability. The causes of allograft valve degeneration are still unknown. The study aims to identify factors associated with cryopreserved allograft valve degeneration. Knowledge of such factors will improve our understanding of the potential causes and mechanisms of allograft heart valve degeneration. (For complete abstract open document)
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Chan, Chun-wai, and 陳春慧. "In-vitro study of the cryopreserved intervertebral disc." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41290380.

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BARATTO, Francesca. "Infezioni protesiche nella chirurgia vascolare ricostruttiva." Doctoral thesis, 2013. http://hdl.handle.net/11562/504561.

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Introduzione: presentiamo un’analisi retrospettiva dei risultati a medio e lungo termine sulla ricostruzione in situ con homograft arterioso criopreservato utilizzato nel trattamento delle infezioni protesiche aorto-iliache. Materiali e metodi: da Gennaio 2002 a Dicembre 2012, 25 pazienti con diagnosi di infezione protesica aorto-iliaca sono stati sottoposti ad intervento di asportazione protesica e ricostruzione in situ con allograft arterioso criopreservato presso l’Unità Operativa Complessa di Chirurgia Vascolare dell’Ospedale Santa Chiara di Trento. Tutti i pazienti furono seguiti al follow-up mediante visita clinica e angio-TC addome ad uno e sei mesi durante il primo anno, successivamente mediante ecocolor doppler aorto-iliaco annualmente, riservando l’angio-TC solo in casi selezionati. Il follow-up medio fu di 46 mesi (range 2-112), 3 pazienti furono persi al follow-up. Risultati: alla laparotomia esplorativa 9 pazienti (36%) presentavano una fistula aorto-enterica. La ricostruzione chirurgica in situ consistette in 5 by pass aorto-aortici, 4 aorto-bisiliaci, 11 aorto-bifemorali, 3 aorto-iliaci con anastomosi femorale controlaterale e 2 by pass iliaco-femorali. Un paziente (4%) necessitò della precoce rimozione dell’homograft e confezionamento di by-pass axillo-femorale a causa di una deiscenza intestinale recidiva. La mortalità post-operatoria fu del 24%, un paziente (4%) morì per shock emorragico provocato dalla rottura precoce dell’homograft, altri 5 pazienti (20%) morirono per complicanze settiche dovute a deiscenza intestinale recidiva. Tra i 18 pazienti seguiti al follow-up, vennero eseguiti 2 re-interventi (11%): uno dovuto a trombosi ed re-infezione protesica, l’altro, invece, a fistola aorto-enterica con deiscenza dell’anastomosi aortica prossimale. Non ci furono amputazioni maggiori. Conclusioni: nella nostra esperienza la ricostruzione in situ con homograft arterioso criopreservato mostra ridotti tassi di mortalità e morbilità e può essere considerata una valida alternativa nel trattamento delle infezioni protesiche aortiche addominali.
Introduction: We report a retrospective analysis of medium and long-term results about in situ reconstruction with cryopreserved arterial allograft (CAA) for aorto-iliac prosthetic infections. Material and methods: From January 2002 to December 2012, 25 patients with diagnoses of aorto-iliac prosthetic infection, underwent in situ arterial allograft replacement at the Department of Vascular Surgery, Santa Chiara Hospital, Trento. All patients were followed by clinical examination and CT at 1 and 6 months during the first year, thereafter by yearly duplex scanner and CT-scan in selected cases. Mean follow-up was 46 months (range 2-112); 3 patients were lost at follow-up. Results: At the explorative laparotomy 9 patients (36%) showed an aorto-enteric fistula (AEF). Surgical in situ reconstruction consisted of 5 aorto-aortic, 4 aorto-bisiliac, 11 aorto-bifemoral, 3 aorto-iliac with controlateral femoral anastomoses and 2 iliac-femoral by-passes. One patient (4%) needed early allograft removal and axillobifemoral reconstruction due to recurrent AEF. Overall post-operative mortality rate was 24%; one patient (4%) died for haemorrhagic shock due to homograft rupture, other five patients (20%) died for septic shock caused by persistent enteric fistula. Among the 18 patients at follow-up, two reinterventions (11%) were required: one due to graft thrombosis and recurrent, the other one due to proximal anastomoses. No major limb amputations were recorded. Conclusions: In our experience in situ reconstruction with cryopreserved arterial homograft showed low morbidity and mortality rates and should be considered a valid option for the treatment of abdominal aortic prosthetic infections.
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Books on the topic "Cryopreserved homograft"

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Brockbank, Kelvin G. M., 1952-, ed. Principles of autologous, allogeneic, and cryopreserved venous transplantation. New York: Springer-Verlag, 1995.

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Book chapters on the topic "Cryopreserved homograft"

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Jonas, R. A., G. Ziemer, L. Armiger, L. Britton, and A. R. Castaneda. "Cryopreserved and fresh valved aortic homograft conduits in a chronic sheep model: Haemodynamic, angiographic and histological comparisons." In Cardiac Valve Allografts 1962–1987, 65–68. Heidelberg: Steinkopff, 1988. http://dx.doi.org/10.1007/978-3-642-72420-6_13.

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Vogt, P. R., and M. I. Turina. "Cryopreserved aortic homografts for mycotic aneurysms and infected arterial grafts." In Cardiac Valve Allografts, 227–41. Heidelberg: Steinkopff, 1997. http://dx.doi.org/10.1007/978-3-642-59250-8_23.

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Yankah, A. C., Y. Weng, J. Hofmeister, V. Alexi-Meskhishvili, H. Siniawski, P. E. Lange, and R. Hetzer. "Clinical results of freehand subcoronary aortic valve and root replacement with cryopreserved homografts (allografts)." In Cardiac Valve Allografts, 143–59. Heidelberg: Steinkopff, 1997. http://dx.doi.org/10.1007/978-3-642-59250-8_15.

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YANKAH, A. C. "IMMUNOGENICITY AND FATE OF CRYOPRESERVED ALLOGRAFT (HOMOGRAFT) VALVES." In Advances in Tissue Banking, 239–53. WORLD SCIENTIFIC, 1999. http://dx.doi.org/10.1142/9789812815262_0013.

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SÁNCHEZ-IBÁÑEZ, JACINTO. "PROCUREMENT, PROCESSING AND CLINICAL ASPECTS OF CRYOPRESERVED VASCULAR HOMOGRAFTS." In Advances in Tissue Banking, 375–86. WORLD SCIENTIFIC, 2002. http://dx.doi.org/10.1142/9789812776976_0021.

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