Academic literature on the topic 'Cruciform structure'

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Journal articles on the topic "Cruciform structure"

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Ait Saada, Anissia, Alex B. Costa, Ziwei Sheng, Wenying Guo, James E. Haber, and Kirill S. Lobachev. "Structural parameters of palindromic repeats determine the specificity of nuclease attack of secondary structures." Nucleic Acids Research 49, no. 7 (March 27, 2021): 3932–47. http://dx.doi.org/10.1093/nar/gkab168.

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Abstract Palindromic sequences are a potent source of chromosomal instability in many organisms and are implicated in the pathogenesis of human diseases. In this study, we investigate which nucleases are responsible for cleavage of the hairpin and cruciform structures and generation of double-strand breaks at inverted repeats in Saccharomyces cerevisiae. We demonstrate that the involvement of structure-specific nucleases in palindrome fragility depends on the distance between inverted repeats and their transcriptional status. The attack by the Mre11 complex is constrained to hairpins with loops <9 nucleotides. This restriction is alleviated upon RPA depletion, indicating that RPA controls the stability and/or formation of secondary structures otherwise responsible for replication fork stalling and DSB formation. Mus81-Mms4 cleavage of cruciforms occurs at divergently but not convergently transcribed or nontranscribed repeats. Our study also reveals the third pathway for fragility at perfect and quasi-palindromes, which involves cruciform resolution during the G2 phase of the cell cycle.
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Timsit, Youri, and Dino Moras. "Cruciform structures and functions." Quarterly Reviews of Biophysics 29, no. 4 (December 1996): 279–307. http://dx.doi.org/10.1017/s0033583500005862.

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In this paper, a structure-function analysis of B-DNA self-fitting is reviewed in the light of recent oligonucleotide crystal structures. Their crystal packings provided a high-resolution view of B-DNA helices closely and specifically fitted by groove-backbone interaction, a natural and biologically relevant manner to assemble B-DNA helices. In revealing that new properties of the DNA molecule emerge during condensation, these crystallographic studies have pointed to the biological importance of DNA—DNA interactions.
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Nag, Dilip K., and Alicia Kurst. "A 140-bp-Long Palindromic Sequence Induces Double-Strand Breaks During Meiosis in the Yeast Saccharomyces cerevisiae." Genetics 146, no. 3 (July 1, 1997): 835–47. http://dx.doi.org/10.1093/genetics/146.3.835.

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Palindromic sequences have the potential to form hairpin or cruciform structures, which are putative substrates for several nucleases and mismatch repair enzymes. A genetic method was developed to detect such structures in vivo in the yeast Saccharomyces cerevisiae. Using this method we previously showed that short hairpin structures are poorly repaired by the mismatch repair system in S. cerevisiae. We show here that mismatches, when present in the stem of the hairpin structure, are not processed by the repair machinery, suggesting that they are treated differently than those in the interstrand base-paired duplex DNA. A 140-bp-long palindromic sequence, on the contrary, acts as a meiotic recombination hotspot by generating a site for a double-strand break, an initiator of meiotic recombination. We suggest that long palindromic sequences undergo cruciform extrusion more readily than short ones. This cruciform structure then acts as a substrate for structure-specific nucleases resulting in the formation of a double-strand break during meiosis in yeast. In addition, we show that residual repair of the short hairpin structure occurs in an MSH2-independent pathway.
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Nobile, C., J. Nickol, and R. G. Martin. "Nucleosome phasing on a DNA fragment from the replication origin of simian virus 40 and rephasing upon cruciform formation of the DNA." Molecular and Cellular Biology 6, no. 8 (August 1986): 2916–22. http://dx.doi.org/10.1128/mcb.6.8.2916.

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Nucleosomes were reconstituted in vitro from a fragment of DNA spanning the simian virus 40 minimal replication origin. The fragment contains a 27-base-pair palindrome (perfect inverted repeat). DNA molecules with stable cruciform structures were generated by heteroduplexing this DNA fragment with mutants altered within the palindromic sequence (C. Nobile and R. G. Martin, Int. Virol., in press). Analyses of the structural features of the reconstituted nucleosomes by the DNase I footprint technique revealed two alternative DNA-histone arrangements, each one accurately phased with respect to the uniquely labeled DNA ends. As linear double-stranded DNA, a unique core particle was formed in which the histones strongly protected the regions to both sides of the palindrome. The cruciform structure seemed to be unable to associate with core histones and, therefore, an alternative phasing of the histone octamer along the DNA resulted. Thus, nucleosome positioning along a specific DNA sequence appears to be influenced in vitro by the secondary structure (linear or cruciform) of the 27-base-pair palindrome. The formation of cruciform structures in vivo, if they occur, might therefore represent a molecular mechanism by which nucleosomes are phased.
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Nobile, C., J. Nickol, and R. G. Martin. "Nucleosome phasing on a DNA fragment from the replication origin of simian virus 40 and rephasing upon cruciform formation of the DNA." Molecular and Cellular Biology 6, no. 8 (August 1986): 2916–22. http://dx.doi.org/10.1128/mcb.6.8.2916-2922.1986.

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Nucleosomes were reconstituted in vitro from a fragment of DNA spanning the simian virus 40 minimal replication origin. The fragment contains a 27-base-pair palindrome (perfect inverted repeat). DNA molecules with stable cruciform structures were generated by heteroduplexing this DNA fragment with mutants altered within the palindromic sequence (C. Nobile and R. G. Martin, Int. Virol., in press). Analyses of the structural features of the reconstituted nucleosomes by the DNase I footprint technique revealed two alternative DNA-histone arrangements, each one accurately phased with respect to the uniquely labeled DNA ends. As linear double-stranded DNA, a unique core particle was formed in which the histones strongly protected the regions to both sides of the palindrome. The cruciform structure seemed to be unable to associate with core histones and, therefore, an alternative phasing of the histone octamer along the DNA resulted. Thus, nucleosome positioning along a specific DNA sequence appears to be influenced in vitro by the secondary structure (linear or cruciform) of the 27-base-pair palindrome. The formation of cruciform structures in vivo, if they occur, might therefore represent a molecular mechanism by which nucleosomes are phased.
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Leach, David R. F. "Long DNA palindromes, cruciform structures, genetic instability and secondary structure repair." BioEssays 16, no. 12 (December 1994): 893–900. http://dx.doi.org/10.1002/bies.950161207.

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Polishchuk, M. A., and M. V. Polishchuk. "Unmanned cruciform winged glider dynamics and control." Journal of «Almaz – Antey» Air and Space Defence Corporation, no. 3 (September 30, 2018): 55–60. http://dx.doi.org/10.38013/2542-0542-2018-3-55-60.

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Tha paper focuses on the problems of unmanned cruciform winged glider dynamics and control in autonomous flight conditions, and studies the wing aspect ratio effect on its flight performance. The winged glider control structure in the longitudinal and lateral axes is proposed. We carried out a comparative analysis of the ballistic flight ranges of models of different configurations, as well as the flight ranges of models of different configurations in the operating conditions of the control system of the proposed structure. As a result, the structure of the unmanned winged glider targeting system is proposed. The targeting system in the longitudinal axis, unlike the samples used in currently operating models, consists of two subsystems responsible for the unmanned winged glider best range gliding at the first flight phase and the direct aimpoint guidance at the second, i.e. final, flight stage
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Fridlyander, I. N., E. A. Tkachenko, A. Galliot, J. Koshorst, V. Y. Valkov, and V. V. Budanov. "Structure and Properties of 1933 Cruciform Large Fitting Blanks." Materials Science Forum 331-337 (May 2000): 1365–68. http://dx.doi.org/10.4028/www.scientific.net/msf.331-337.1365.

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Lader, Pål, Birger Enerhaug, Arne Fredheim, Pascal Klebert, and Bjørnar Pettersen. "Forces on a cruciform/sphere structure in uniform current." Ocean Engineering 82 (May 2014): 180–90. http://dx.doi.org/10.1016/j.oceaneng.2014.03.007.

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Gao, Xinglong, Qingbin Zhang, Qin Chen, and Wenkai Wang. "Fluid-structure Interactions on Steerable Cruciform Parachute Inflation Dynamics." IOP Conference Series: Materials Science and Engineering 751 (February 7, 2020): 012010. http://dx.doi.org/10.1088/1757-899x/751/1/012010.

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Dissertations / Theses on the topic "Cruciform structure"

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Nyczová, Adéla. "Analýza lokálních struktur v molekulách DNA." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2021. http://www.nusl.cz/ntk/nusl-445146.

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Local DNA structures are alternative DNA conformations which can be formed aside from typical B-DNA conformation. These structures often play pivotal roles in regulation of basic biological processes, such as DNA replication, transcription or binding of specific ligands. This biological significance makes alternative DNA secondary structures a potential drug target. In this diploma thesis, local structures in genomes of viruses from Flaviviridae and Retroviridae families are analysed using bioinformatics tools. Furthermore, these structures are visualised using atomic force microscopy.
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Shrestha, Alina. "Fatigue Testing and Data Analysis of Welded Steel Cruciform Joints." ScholarWorks@UNO, 2013. http://scholarworks.uno.edu/td/1670.

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In this study, ABS Publication 115, “Guidance on Fatigue Assessment of Offshore Structures” is briefly reviewed. Emphasis is on the S-N curves based fatigue assessment approach of non-tubular joints, and both size and environment effects are also considered. Further, fatigue tests are performed to study the fatigue strength of load-carrying and non-load-carrying steel cruciform joints that represent typical joint types in marine structures. The experimental results are then compared against ABS fatigue assessment methods, based on nominal stress approach, which demonstrates a need for better fatigue evaluation parameter. A good fatigue parameter by definition should be consistent and should correlate the S-N data well. The equivalent structural stress parameter is introduced to investigate the fatigue behavior of welded joints using the traction based structural stress approach on finite element models of specimens, and representing the data as a single Master S-N curve.
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Coudon, Florent. "Comportement mécanique du superalliage base nickel à solidification dirigée DS200+Hf." Thesis, Paris Sciences et Lettres (ComUE), 2017. http://www.theses.fr/2017PSLEM062/document.

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De nombreuses études ont permis de développer des modèles de plasticité cristalline rendant compte de l’anisotropie d’un monocristal. Les matériaux à solidification dirigée (DS) peuvent être simulés avec des modèles semblables, sous réserve de connaître la morphologie et l'orientation cristallographique des grains contenus dans la pièce. Pour éviter ces analyses microstructurales coûteuses, il est possible de développer des approches, déterministes ou analysant les dispersions de la réponse sur un lot de << pièces synthétiques >> résolues par la méthode des éléments finis. Dans cette étude, nous avons tenté d'apporter les outils nécessaires aux deux types de modélisation. Avant tout, un modèle du monograin de DS200+Hf a été identifié pour une gamme de température allant de l’ambiante à 1200°C. Ensuite, plusieurs montées d'échelle ont été envisagées, d'abord sur un volume élémentaire représentatif (VER) puis sur une structure tridimensionnelle (éprouvette cruciforme). Sur le VER, la réponse de plusieurs modèles micromécaniques a été confrontée à des calculs de référence utilisant la méthode des éléments finis. Puis, le comportement mécanique d'une éprouvette cruciforme en DS200+Hf a été étudié, en réalisant des essais expérimentaux biaxiaux qui, ensuite, ont permis d'évaluer les prévisions du modèle. Ces résultats amènent à s'interroger sur la modélisation adaptée aux structures oligogranulaires (i.e. constituées d’un faible nombre de grains) : faut-il mailler explicitement l'échelle locale (les grains) dans la structure ou malgré la non-séparabilité des échelles, le modèle homogénéisé continue-t-il de fournir des résultats satisfaisants ?
Various studies were aimed at developing crystal plasticity models to account for the anisotropic mechanical behaviour of single crystals. Directionally solidified (DS) materials can be modeled using such approaches, taking into account the underlying crystallographic structure. It requires the knowledge of the position, shape and crystallographic orientations of grains. To prevent heavy microstructure analyses, other models have to be developed for industrial calculations, using homogenization theory or considering a batch of synthetic pieces calculated using Crystal Plasticity Finite Elements Method (CPFEM). The aim of this thesis is to bring computational tools to carry out the two types of modeling for industrial applications. First of all, a crystal plasticity model for one grain of DS200+Hf is defined ranging from room temperature to 1200°C. Some scale transition rules, using full-field or mean-field approaches, are studied first in the theoretical case of a representative volume element (RVE) and then on tri-dimensional structures in order to access overall and local responses. For the RVE responses, micromechanical models are compared with a reference produced by CPFEM for various loadings. Moreover, the mechanical behaviour of a DS200+Hf cruciform specimen is studied. Biaxial tests with digital image correlation allow us to check the model predictions. These results raise questions about the modeling of oligogranular structures (i.e. with a small number of grains): should it be accepted that the local scale must be explicitly meshed, or, despite the fact that scale separability is not ensured, can we consider that the homogenized model still produces reliable results?
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McGrier, Psaras Lamar. "Hydroxy cruciforms and bis(hydroxystyryl)benzenes: synthesis, structure, and photophysical properties of novel π-systems." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/37185.

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This thesis examines the synthesis, photophysical properties, and sensory responses of hydroxy-substituted 1,4-distyryl-2,5-bis(arylethynyl)benzenes (Cruciforms, XFs). These two-dimensional cross-conjugated materials possess spatially separated frontier molecular orbitals (FMOs). This spatial separation allows the HOMO and LUMO to be addressed independently by analytes, which leads to significant changes in their absorption and emission. These properties allow XFs to be utilized for the detection of various analytes. These studies highlight the benefits of utilizing XFs for the development of advanced functional solid state materials for sensory applications.
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Paré-Lambert, Olivier. "Étude de l'extraction d'énergie du phénomène de Vibrations Induites par Vortex (VIV) lorsque deux cylindres sont placés de façon cruciforme." Master's thesis, Université Laval, 2020. http://hdl.handle.net/20.500.11794/67578.

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Šedý, Michal. "Analýza lokalizace inverzních repetic v bakteriálních genomech." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2021. http://www.nusl.cz/ntk/nusl-449791.

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Inverted repeats (IR) are common part of DNA of all living prokaryotic and eukaryotic organisms. Inverted repeats plays an important role in the regulation of basics cells processes. They are responsible for formation of cruciform structures. Inverted repeats also cause genomic instability and can be a source of numerous mutations. Cruciform structures can be recognized by DNA-binding proteins and can also act as a transcriptional regulators. Using the Palindrome Analyser tool, the frequency of IR and localization of inverted repeats in bacterial genomes was analyzed. The frequency of IR across the bacterial genome is variable. The frequency of short inverted repeats shows an approximately quadratic dependence on the %GC content in the genome with a minimum of about 50% of GC content. The localization of inverted repeats with respect to “annotated features” show a non-random distribution. The frequency of IR for most features is higher “outside” than “inside”.
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Ratnasinghe, Duminda D. "Unusual Structure of a Human Middle Repetitive DNA." Digital Commons @ East Tennessee State University, 1993. https://dc.etsu.edu/etd/2767.

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The L2Hs sequences are a polymorphic, interspersed, middle repetitive DNA family unique to human genomes. Genomic fingerprinting indicates that these DNAs vary from one individual to another and between tissues of the same individual. Sequence analysis reveals that they are AT-rich (76%) and contain many unusual sequence arrangements (palindromes, inverted and direct repeats). These sequence properties confer on the L2Hs elements the potential to fold into non-B-form structures, a characteristic of recombination hot spots. To test this hypothesis carbodiimide, osmium tetroxide and S$\sb1$ nuclease were used as single-strand specific probes to study a recombinant plasmid, pN6.4.39, containing a single L2Hs segment. Different forms of the plasmid substrate were analyzed, including linear molecules and circular forms of low, intermediate and high superhelical densities. In addition, plasmid DNA in growing E. coli cells were analyzed. Modified plasmid DNA was analyzed by primer extension in a sequencing-type reaction format. These studies demonstrate that the L2Hs sequences: (1) assume non-B-form structures both in vitro and in vivo, (2) map to predicted cruciform structures, (3) behave as C-type extrusion sequences, and (4) that these unusual DNA structures are dependent on plasmid superhelicity.
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Sin, Ousphea. "Étude en deux dimensions de l'effet du taux de déformation sur la limite élastique de l'acier structural." Mémoire, Université de Sherbrooke, 2017. http://hdl.handle.net/11143/11237.

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L’évaluation de la résistance probable des éléments dissipatifs d’énergie sismique lors du dimensionnement parasismique des charpentes d’acier au Canada repose sur la limite élastique probable de l’acier. Les taux de déformation élevés dans les éléments dissipatifs au cours d’un tremblement de terre ont pour effet d’augmenter la limite élastique de l’acier dans ces éléments. Le comportement dynamique de l’acier étudié par le biais d’essais uniaxiaux conventionnels ne permettent pas nécessairement de valider le comportement d’un élément dissipateur d’énergie sismique pouvant être sollicité selon deux dimensions. Les cadres contreventés excentriques, où le lien ductile subi des déformations biaxiales par les effets combinés du cisaillement et de la flexion en est un exemple. Le projet de recherche présenté dans ce mémoire de maîtrise vise à évaluer l’effet du taux de déformation sur la limite élastique de l’acier structural de grade 350W lors de sollicitations impliquant un état planaire de contrainte. La conception d’une éprouvette cruciforme optimale en acier basée sur des recommandations proposés dans la littérature et sur des analyses par éléments finis a été effectuée. Six essais de traction uniaxiaux et quatre essais de traction équibiaxiaux sur éprouvettes cruciformes ont été réalisés à différents taux de déformation entre 0.0001/sec et 2.4/sec. Durant ces essais, les déformations moyennes à travers la partie centrale des éprouvettes ont été mesurées par un système de potentiomètre conçu dans le cadre de ce projet. Quatre essais biaxiaux sur éprouvettes cruciformes selon des rapports de déformation distincts ont également été réalisés à un taux de déformation quasi-statique. Chaque essai a été simulé numériquement à l’aide d’un modèle éléments finis dans lequel la limite élastique a été calibrée afin de reproduire le comportement observé lors des essais. Le critère d’écoulement plastique de Von Mises ainsi qu’une formulation d’écrouissage non-linéaire ont été adoptés lors des analyses numériques. Les modèles calibrées ont permis de déterminer la limite élastique dynamique observée lors de chaque essai. Les résultats des analyses confirment que la limite élastique de l’acier augmente en fonction du taux effectif de déformation. Sept lois de prédiction de la limite élastique de l’acier ont été étudiées. Trois lois ont permis de représenter la limite élastique dynamique de l’acier testé dans la plage des taux de déformation étudiée. La loi qui semble la mieux adaptée à être implémentée dans un logiciel de modélisation a été identifiée. La loi de Drysdale et Zak utilisé dans le logiciel ADINA ne permet pas d’évaluer correctement le comportement dynamique observé lors des essais impliquant un taux élevé de déformation. Une étude numérique préliminaire sur le lien ductile est également présentée dans ce mémoire.
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Bosland, Paul W. "The genetics and population structure of Fusarium oxysporum from crucifers." 1986. http://catalog.hathitrust.org/api/volumes/oclc/14107323.html.

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Thesis (Ph. D.)--University of Wisconsin--Madison, 1986.
Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 101-114).
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Books on the topic "Cruciform structure"

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Ambrogio e la cruciforme "Romana" basilica degli apostoli nei milleseicento anni della sua storia. Milano: NED, 1986.

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Book chapters on the topic "Cruciform structure"

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Lilley, David M. J. "The Cruciform Extrusion Transition in Supercoiled DNA Molecules." In Structure, Dynamics and Function of Biomolecules, 217–23. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71705-5_46.

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Lilley, David M. J. "The Structure and Physical Chemistry of Cruciform Structures in Supercoiled DNA." In Structure and Dynamics of Biopolymers, 112–36. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3619-5_7.

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Lilley, David M. J., Karen M. Sullivan, Alastair I. H. Murchie, and Judy C. Furlong. "Cruciform Extrusion in Supercoiled DNA — Mechanisms and Contextual Influence." In Unusual DNA Structures, 55–72. New York, NY: Springer New York, 1988. http://dx.doi.org/10.1007/978-1-4612-3800-3_4.

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Pang, H. L. J., and T. G. F. Gray. "Fatigue Analysis of Unstress-Relieved Cruciform Welded Joints." In Fracture of Engineering Materials and Structures, 639–44. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3650-1_94.

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Saharan, Govind Singh, Prithwi Raj Verma, Prabhu Dayal Meena, and Arvind Kumar. "Fine Structures." In White Rust of Crucifers: Biology, Ecology and Management, 189–92. New Delhi: Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1792-3_11.

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Pettijohn, David E., Richard R. Sinden, and Steven S. Broyles. "Cruciform Transitions Assayed Using a Psoralen Crosslinking Method: Applications to measurements of DNA torsional tension." In Unusual DNA Structures, 103–14. New York, NY: Springer New York, 1988. http://dx.doi.org/10.1007/978-1-4612-3800-3_7.

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Smits, A., D. Lecompte, D. Van Hemelrijck, H. Sol, and W. Van Paepegem. "Inverse Method for Parameter Determination of Biaxially Loaded Cruciform Composite Specimens." In Experimental Analysis of Nano and Engineering Materials and Structures, 931–32. Dordrecht: Springer Netherlands, 2007. http://dx.doi.org/10.1007/978-1-4020-6239-1_463.

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Lilley, D. M. J., K. M. Sullivan, and A. I. H. Murchie. "The Extrusion of Cruciform Structures in Supercoiled DNA — Kinetics and Mechanisms." In Nucleic Acids and Molecular Biology, 126–37. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-46596-3_7.

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Lamkanfi, E., A. Smits, W. Van Paepegem, and D. Van Hemelrijck. "Application of Ultrasonic Phased Array for Nondestructive Detection of Damage in Biaxial Cruciform." In Experimental Analysis of Nano and Engineering Materials and Structures, 941–42. Dordrecht: Springer Netherlands, 2007. http://dx.doi.org/10.1007/978-1-4020-6239-1_468.

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Singh Saharan, Govind, Naresh Mehta, and Prabhu Dayal Meena. "Fine Structures and Electron Microscopy." In Alternaria Diseases of Crucifers: Biology, Ecology and Disease Management, 163–66. Singapore: Springer Singapore, 2015. http://dx.doi.org/10.1007/978-981-10-0021-8_7.

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Conference papers on the topic "Cruciform structure"

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Mohanty, Subhasish, Aditi Chattopadhyay, Pedro Peralta, and Dan Quech. "Fatigue damage prognosis of a cruciform structure under biaxial random and flight profile loading." In SPIE Smart Structures and Materials + Nondestructive Evaluation and Health Monitoring, edited by Peter J. Shull, Aaron A. Diaz, and H. Felix Wu. SPIE, 2010. http://dx.doi.org/10.1117/12.848814.

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Lee, Kuk-Hee, Yun-Jae Kim, Robert A. Ainsworth, David Dean, and Tae-Eun Jin. "Elastic Follow-Up Factor for Cruciform Plate Under Bi-Axial Loading." In ASME 2011 Pressure Vessels and Piping Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/pvp2011-57185.

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This paper derives analytical solutions of the elastic follow-up factor for power-law creeping cruciform plates under bi-axial displacements to investigate the effect of multi-axial stress states on elastic follow-up behaviors. Validity of the proposed solutions is checked against the results from finite element analyses using power-law creep material. Based on proposed solutions, effects of the biaxiality, geometry, Poisson’s ratio and creep exponent on elastic follow-up factors are discussed. Present results show that the elastic follow-up factor for structure with structural discontinuity can be significantly affected by the multi-axial stress states.
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QIU, LEI, SHENFANG YUAN, and BIN LIU. "Damage Imaging of Aircraft Composite Structure Based on 2-D Cruciform PZT Array and Spatial-Wavenumber Filters." In Structural Health Monitoring 2015. Destech Publications, 2015. http://dx.doi.org/10.12783/shm2015/73.

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Kim, Jong-Min, Ki-Hyoung Lee, Ho-Jin Lee, and Bong-Sang Lee. "Evaluation of Fracture Toughness Behavior of SA508 Steel Considering Biaxial Loading Condition." In ASME 2012 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/pvp2012-78689.

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The crack-tip stress field and fracture mechanics assessment parameters, such as the elastic stress intensity factor and the elastic-plastic J-integral, for a surface crack can be significantly affected by the loading condition and crack geometry. Current guidance considers that the ductile-to-brittle transition is defined using uniaxially loaded specimens with a deep crack even when the reactor pressure vessel is under biaxial loading and the existence of deep crack is not probable through periodic in-service-inspection. Thus, such a constraint effect caused by differences between standard specimens and a real structure can overestimate the fracture toughness and affects the results of the structural integrity assessment. The present paper investigates the constraint effect by evaluating the Mater Curve T0 reference temperature of PCVN (Pre-cracked Charpy V-Notch) and small scale cruciform specimens of SA508 Gr. 3 low alloy steel through the fracture toughness tests of theses specimens and 3-dimensional elastic-plastic finite element analyses. Based on the finite element results, the fracture toughness values of a small-scale cruciform specimen were estimated, and the geometry-dependent factors of the cruciform specimen considered in the present study were determined and then the transferability of the test results of these specimens were discussed.
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Limansky, Alex, and Olga Y. Limanskaya. "Inverted repeats: computer analysis of microorganism genome and imaging of cruciform structure in DNA by atomic force microscopy." In Microtechnologies for the New Millennium 2003, edited by Angel Rodriguez-Vazquez, Derek Abbott, and Ricardo Carmona. SPIE, 2003. http://dx.doi.org/10.1117/12.501637.

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Zhang, Jinjun, Kuang Liu, and Aditi Chattopadhyay. "Fatigue Life Prediction Under Biaxial FALSTAFF Loading Using Statistical Volume Element Based Multiscale Modeling." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-86341.

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This article presents the fatigue life prediction in a cruciform specimen of 2024-T351 aluminum alloy subjected to biaxial FALSTAFF loading. An energy- and slip-based multiscale damage criterion is developed to capture the fatigue crack formation in crystalline metallic materials. In these materials, there are two stages in crack initiation: nucleation of micro cracks and coalescence of micro cracks into major cracks. In the first stage, micro cracks generate from intermetallic particles and extend into surrounding grains. For the FCC crystalline structure, fatigue damage increments in four dependent slip planes are calculated and accumulated to measure micro crack. In the second stage, the micro cracks grow and coalesce into major cracks. Subsequently, a meso-statistical volume element model is developed to represent the microstructure of the material. Finally, a root mean square method is introduced to take into account FALSTAFF loading. Using the root mean square (RMS) method, the loading history for tests is analyzed to determine the RMS maximum and minimum stresses. The multiscale damage criterion, statistical volume element and RMS method were validated using previously conducted fatigue tests on cruciform samples. The fatigue life and crack direction predicted using the developed model correlate well with the experiments.
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Bogdanov, Sergey, Semyon Mikheevskiy, and Grzegorz Glinka. "The Fatigue Life Prediction Methodology Based on the Unigrow Model." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-53693.

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This paper is concerned with the problem of prediction of the total life of an engineering structure based on the fatigue crack growth model. The life of an engineering component is generally modeled as a combination of the time required for a crack to initiate and then the time required for crack to propagate till the final fracture. Unfortunately the crack initiation size is a vaguely defined parameter. In order to overcome this ambiguity it is proposed to model the total life of an engineering structure by using the UniGrow fatigue crack growth model with assumption of the intrinsic material parameter ρ* as an initial crack size. The method to overcome the small crack problem in fatigue crack modeling is presented as well. The proposed model was successfully used to predict fatigue lives of misaligned cruciform welded joints under a constant amplitude loading. Results from the analysis and experiment are in a good agreement.
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O'Claire, David E., and David M. Hesse. "Transmission Towers with Cruciform Legs." In Electrical Transmission and Substation Structures Conference 2012. Reston, VA: American Society of Civil Engineers, 2012. http://dx.doi.org/10.1061/9780784412657.024.

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Mohanty, Subhasish, Aditi Chattopadhyay, Jun Wei, and Pedro Peralta. "On-Line Structural Health Monitoring and Prognosis of a Biaxial Cruciform Specimen." In 50th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2009. http://dx.doi.org/10.2514/6.2009-2305.

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Han, Lin-Han, and Kan Zhou. "Fire performance of concrete-encased CFST columns and beam-column joints." In 12th international conference on ‘Advances in Steel-Concrete Composite Structures’ - ASCCS 2018. Valencia: Universitat Politècnica València, 2018. http://dx.doi.org/10.4995/asccs2018.2018.6927.

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Concrete-encased CFST (concrete filled steel tube) structure is a type of composite structure featuring an inner CFST component and an outer reinforced concrete (RC) component. They are gaining popularity in high-rise buildings and large-span buildings in China nowadays. To date, the behaviour of concrete-encased CFST structures at ambient temperature has been investigated, but their fire performance has seldom been addressed, including the performance in fire and after exposure to fire. This paper summarizes the fire test results of concrete-encased CFST columns and beam-column joints. The cruciform beam-column joint was composed of one continuous concrete-encased CFST column and two cantilevered reinforced concrete (RC) beams. These specimens were subjected to a combined effect of load and full-range fire. The test procedure included four phases, i.e. a loading phase at ambient temperature, a standard fire exposure phase with constant load applied, a sequential cooling phase and a postfire loading phase. The main findings are presented and analysed. Two types of failure were identified, i.e. the failure during fire exposure and the failure during postfire loading. Global buckling failure was observed for all the column specimens. The column specimens with common load ratios achieved high fire ratings without additional fire protection. The concrete-encased CFST columns also retained high postfire residual strength. As for the joint members, beam failure was observed in all cases. The measured temperature-time history and deformation-time history are also presented and discussed. For both the column and joint specimens, the deformation over the cooling phase was significantly greater than that in the standard fire exposure phase.
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