Academic literature on the topic 'Corpus callosum'

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Journal articles on the topic "Corpus callosum"

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Harisha, P. N., V. Umamaheshwar Reddy, Amit Agrawal, and Gopal Kodali. "Massive spontaneous corpus callosal hemorrhage with intraventricular extension." Romanian Neurosurgery 21, no. 2 (June 1, 2014): 209–12. http://dx.doi.org/10.2478/romneu-2014-0023.

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Abstract Spontaneous hemorrhage into the corpus callosum with intraventricular extension is uncommon. In the present article we describe a case 60 year female who had massive hemorrhage along the corpus callosum involving genu, body of corpus callosum and extending on ventral as well as dorsal aspect of the corpus callosum with intraventricular extension and areas of hypodensities in the body of the corpus callosum and adjacent cerebral cortex. In this case the subarachnoid and corpus callosal hemorrhage probably resulted from the ruptured aneurysms of the anterior cerebral artery.
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Ku, Ray, and Masaaki Torii. "New Molecular Players in the Development of Callosal Projections." Cells 10, no. 1 (December 26, 2020): 29. http://dx.doi.org/10.3390/cells10010029.

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Cortical development in humans is a long and ongoing process that continuously modifies the neural circuitry into adolescence. This is well represented by the dynamic maturation of the corpus callosum, the largest white matter tract in the brain. Callosal projection neurons whose long-range axons form the main component of the corpus callosum are evolved relatively recently with a substantial, disproportionate increase in numbers in humans. Though the anatomy of the corpus callosum and cellular processes in its development have been intensively studied by experts in a variety of fields over several decades, the whole picture of its development, in particular, the molecular controls over the development of callosal projections, still has many missing pieces. This review highlights the most recent progress on the understanding of corpus callosum formation with a special emphasis on the novel molecular players in the development of axonal projections in the corpus callosum.
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Naimi, S., S. Faiz, Y. Bouktib, A. Elhejjami, B. Boutakioute, M. Ouali Idrissi, and N. Cherif Idrissi El Ganouni. "Corpus Callosum Infarction: Case Report." SAS Journal of Medicine 10, no. 03 (March 7, 2024): 175–77. http://dx.doi.org/10.36347/sasjm.2024.v10i03.006.

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Corpus callosum infarction is uncommon mostly because of rich vascular supply and collateral circulations. It´s shares the same risk factors as other cerebral locations. MRI establishes the diagnosis of ischemic stroke of the corpus callosum, particularly through the diffusion-weighted sequence. Our article offers a thorough understanding of callosal infarction, aiding clinicians in early diagnosis, timely intervention, and substantially enhancing prognosis.
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Utz, Shelby E. "Corpus Callosum." International Journal of Undergraduate Research and Creative Activities 11 (April 24, 2019): 3. http://dx.doi.org/10.7710/2168-0620.1122.

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Ryan, Stephanie, and Veronica Donoghue. "Corpus Callosum." American Journal of Roentgenology 176, no. 5 (May 2001): 1328. http://dx.doi.org/10.2214/ajr.176.5.1761328a.

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Pearce, J. M. S. "Corpus Callosum." European Neurology 57, no. 4 (2007): 249–50. http://dx.doi.org/10.1159/000101293.

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Raybaud, Charles. "Corpus Callosum." Neuroimaging Clinics of North America 29, no. 3 (August 2019): 445–59. http://dx.doi.org/10.1016/j.nic.2019.03.006.

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Hattingen, E., M. Nichtweiß, S. Blasel, F. E. Zanella, and S. Weidauer. "Corpus callosum." Der Radiologe 50, no. 2 (December 11, 2009): 152–64. http://dx.doi.org/10.1007/s00117-009-1945-5.

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Durdu, Cristiana-Elena, Vlad Dima, Bianca Margareta Mihai, Ionită Ducu, Ana Maria Cioca, and Roxana-Elena Bohiltea. "The ultrasound evaluation of corpus callosum in the routine screening is not recommended, because we know less than we see." Romanian Journal of Pediatrics 71, S2 (November 30, 2022): 23–26. http://dx.doi.org/10.37897/rjp.2022.s2.5.

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The corpus callosum serves as a link between the two hemispheres, with an important role in cognitive mechanisms, also integrating motor and sensitive information and processing stimuli. Evaluation of the morphologic structure of the corpus callosum in order to diagnose structural anomalies such as hyperplasia, hypoplasia, as well as indirect signs of corpus callosum agenesia can be realised using ultrasonography during the mid-trimester screening. At present, it is recommended to perform a targeted evaluation only in high-risk cases of central nervous system abnormalities; the International Society of Ultrasound in Obstetrics and Gynaecology has not included the corpus callosum evaluation in the routine second trimester screening. Callosal anomalies present uncertainty in the fetal prognosis: 75% of cases of isolated corpus callosum agenesis develop normally; on the other hand, they could develop various degrees of neurological impairment from language or social deficiency to autism or schizophrenia. We, therefore, highlight the importance of corpus callosum evaluation, as the agenesis of the corpus callosum can be an isolated defect, but it can also be associated with other extracerebral anomalies or it could be a part of a syndrome. Completing the diagnosis often requires magnetic resonance imaging and genetic tests.
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K Mounisha, MU Jeevika, BG Mahesh, B Adarsh, and KK Nirnay. "Role of Corpus Callosum in Global Developmental Delay." Asian Journal of Medical Radiological Research 8, no. 1 (July 5, 2020): 128–31. http://dx.doi.org/10.47009/ajmrr.2020.8.1.23.

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Background: Neuroimaging provides essential information as evidence of previous injuries, specific abnormalities that could indicate a group or a particular disease in babies with global developmental delay. The objectives is to assess the difference of corpus callosal size in various regions of the corpus callosum in cases of children with developmental delay and to know the etiology using MRI. Subjects and Methods: My study includes 102 children between 1 to 6 years of age among which 51 children are cases having signs and symptoms of developmental delay and 51 children are controls i.e. healthy babies. They underwent MRI in the Department of Radiology, JJM Medical College, Davangere in whom corpus callosum is imaged on sagittal MR sections and its size is calculated in different regions. Results: Abnormalities of the corpus callosum like thinning and agenesis were observed in 55.5% (N=27) in the study group, and none of the patients in the control group. Partial corpus callosal agenesis was present in 3.9% of patients. Complete agenesis in 3.9% of patients. Thinning of the corpus callosum was seen in 45% of patients who were in the study group. Conclusion: The current study suggests that corpus callosal abnormalities, including brain changes, is useful in knowing the etiology of global developmental delay.
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Dissertations / Theses on the topic "Corpus callosum"

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Horton, James Edward. "Hypnotizability and Corpus Callosum Morphology." Diss., Virginia Tech, 1999. http://hdl.handle.net/10919/27703.

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In general, highly hypnotizable individuals ("highs") have exhibited greater abilities to focus attention and inhibit pain than low hypnotizable individuals ("lows"). Furthermore, highs appear to have faster neural processing than lows. The present study investigated differences between lows and highs in morphological volume of some brain structures associated with inhibitory and excitatory neural processing, particularly the corpus callosum (CC). Participants were 18 healthy university students, aged 18 to 29, with no history of concussion or medical disorders. They were in a functional Magnetic Resonance Image (fMRI) study examining the neurophysiology of pain and hypnotic analgesia (Crawford, Horton, Harrington, et al., 1998; Downs et al., 1998). As assessed by the group version (Crawford & Allen, 1982) of the Stanford Hypnotic Susceptibility Scale, Form C (SHSS:C; Weitzenhoffer & Hilgard, 1962), there were eight highs (four women and four men; SHSS:C M = 11.0) and 10 lows (five men and five women; SHSS:C M = 2.1). Highs were able to successfully eliminate perception of pain and distress to experimental noxious stimuli. Their anatomical MRIs were measured to assess relationships between brain structure volume (CC, medial cortex, anterior brain regions) and hypnotizability. In comparison to lows, highs had a significantly larger CC volume in the rostrum and isthmus, inferred to reflect larger transcallosal axon diameter or greater axon myelination. For highs, but not lows, there were significant relationships between forebrain volume and the total CC, rostrum, and splenium. Findings provide support for the neuropsychophysiological model of Crawford and her associates (e.g. Crawford, 1994a, 1994b; Crawford & Gruzelier, 1992) proposing a more effective attentional system of inhibitory processes in highs than lows. Furthermore, the data suggest that the more effective systems of attentional and inhibitory processes enhanced neural processing speed, and interhemispheric transfer times seen in highs than lows, may be associated with morphological differences in certain anterior and posterior CC regions. These regions are known to be involved in the allocation of inhibitory and excitatory transfer of information between hemispheres.
Ph. D.
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Dean, Christopher. "Symmetry of mouse corpus callosum development." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq21164.pdf.

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Wignall, Emma Louise. "Corpus callosum morphology in health and disease." Thesis, University of Sheffield, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485079.

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The corpus callosum has a distinct topographical organisation along its length, with different cortical areas connecting through different regions of the callosum. This has led to a number of different ways to divide the callosum along its length. The aim of this thesis was to apply a relatively novel method of callosal sub~ivision to look for meaningful brain/behaviour correlations in bimanual coordination and dichotic listening tasks. Measurements of the corpus callosum were obtained from a cohort of healthy adults who underwent magnetic resonance (MR) imaging. The same method was also applied to examine differences in callosal size in adults with Neurofibromatosis type I (NFl), a disease in which a larger callosum has been found in children with NFL In addition, diffusion tensor imaging was also obtained to examine underlying microstructural differences in regions of size difference. Chapter one provides an overview of normal callosal development, topographical arrangement and differences in fibre composition across the length and a discussion of methods of callosal subdivision. Finally, a basic MR physics section and more specifically diffusion tensor imaging is provided. Chapter two is a generic methods section discussing how the callosal measures used to produce brain/behaviour correlations in the subsequent two chapters were obtained. Chapters three and four discuss the brain/behaviour relationships derived from the bimanual coordination (chapter three) and dichotic listening (chapter four) tasks. Chapter five is the examination of callosal size in adults with NFl and mat~hed healthy controls and subsequent diffusion tensor imaging investigation. Finally, chapter six reviews the results of the brain/behaviour correlations, their place in the literature and possible future investigations. The results of chapter five are also discussed with possible future investigations of brain/behaviour relationships. Finally, future methods of callosal divisions based on better understanding of the underlying cortical connections are theorised.
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Galinowski, A., R. Miranda, H. Lemaitre, Martinot M. L. Paillère, E. Artiges, H. Vulser, R. Goodman, et al. "Resilience and corpus callosum microstructure in adolescence." Cambridge University Press, 2015. https://tud.qucosa.de/id/qucosa%3A39053.

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Background. Resilience is the capacity of individuals to resist mental disorders despite exposure to stress. Little is known about its neural underpinnings. The putative variation of white-matter microstructure with resilience in adolescence, a critical period for brain maturation and onset of high-prevalence mental disorders, has not been assessed by diffusion tensor imaging (DTI). Lower fractional anisotropy (FA) though, has been reported in the corpus callosum (CC), the brain’s largest white-matter structure, in psychiatric and stress-related conditions. We hypothesized that higher FA in the CC would characterize stress-resilient adolescents. Method. Three groups of adolescents recruited from the community were compared: resilient with low risk of mental disorder despite high exposure to lifetime stress (n = 55), at-risk of mental disorder exposed to the same level of stress (n = 68), and controls (n = 123). Personality was assessed by the NEO-Five Factor Inventory (NEO-FFI). Voxelwise statistics of DTI values in CC were obtained using tract-based spatial statistics. Regional projections were identified by probabilistic tractography. Results. Higher FA values were detected in the anterior CC of resilient compared to both non-resilient and control adolescents. FA values varied according to resilience capacity. Seed regional changes in anterior CC projected onto anterior cingulate and frontal cortex. Neuroticism and three other NEO-FFI factor scores differentiated non-resilient participants from the other two groups. Conclusion. High FA was detected in resilient adolescents in an anterior CC region projecting to frontal areas subserving cognitive resources. Psychiatric risk was associated with personality characteristics. Resilience in adolescence may be related to white-matter microstructure.
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Wuebbens, Stephanie Ann. "Agenesis of the corpus callosum in preschool children." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1335542204.

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Van, Hook Colin. "The Relationship Between Instrumental Music Training and Corpus Callosum Growth." Thesis, Boston College, 2004. http://hdl.handle.net/2345/467.

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Thesis advisor: Ellen Winner
Recent studies have shown differences between several structures in the brains of professional level musicians and non-musicians. Professional musicians form an ideal group to study changes in the human brain due to the unique abilities required of them. Since many musicians begin training at a young age, it is assumed that these differences are attributable to intense, early experience brought on by the cognitive and motor demands of music training. However, it remains to be seen whether these structural differences are due to changes brought on by experience or preexisting ones which draw children to music lessons. Using magnetic resonance images, I compared the size of the corpus callosums in two groups of children who ranged between the ages of five and seven, one just beginning music lessons and another not beginning music lessons. I also compared the groups in terms of their performance on a finger tapping test for differences in speed and accuracy. A second set of comparisons of callosal size was conducted between nine-to-eleven-year-olds who had been taking music lessons for at least a year and those who had not. Differences in the five-to-seven-year-olds were seen in the anterior corpus callosum corrected for brain volume between the musician and non-musician groups. Differences in accuracy of finger tapping were seen between the musicians and non musicians, as well as between those in the musician group who had received less than sixteen or twenty-five weeks of training versus those who had received less. These findings indicate that while musicians start out with at least one slightly larger measure of corpus callosum size, differences in finger skill tend to develop slowly
Thesis (BA) — Boston College, 2004
Submitted to: Boston College. College of Arts and Sciences
Discipline: Psychology
Discipline: College Honors Program
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Raubenheimer, Lauren. "Corpus callosum morphology in children on mid-sagittal MR imaging." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29692.

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Background: There is little published research on the wide variation of corpus callosum (CC) morphology in children, the assessment of which is made difficult by the complex alteration of its appearance in childhood. Objective: The purpose of our study was to assess the morphology of the CC on mid-sagittal T1- weighted magnetic resonance imaging (MRI) in a large number of children and correlate the findings with demographic and clinical criteria. Materials and methods: We reviewed all brain mid-sagittal T1-weighted MRI’s performed from July to December 2015 and obtained relevant demographic and clinical information from the accompanying report and laboratory system. The CC morphology was analysed by three radiologists and compared using cross tabulation with the chi-square test and ANOVA. Interobserver correlation was assessed using Kappa coefficient of conformance. Results: 257 patients with mean age 72±60 months were included, 142 were male (55%). In abnormal MRI’s the CC was less likely to have an identifiable isthmus and was more likely to be convex, thin and have separation of the fornix insertion (all p<0.01). In young children (< 5 years) the CC was also less likely to have an identifiable isthmus (p=0.01) and was more likely to be convex (p=0.04) but the fornix was more likely to insert normally (p<0.01). Children with tuberous sclerosis had significantly thinner splenia (p=0.02). Conclusion: There is a distinct pathological appearance of the CC. The immature appearance of the corpus callosum can mirror this but is distinguished by normal insertion of the fornix and normal quantitative measurements. Splenial thinning in children with tuberous sclerosis warrants further investigation.
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Bishop, Katherine Mary. "A threshold model for development of the corpus callosum in normal and acallosal mice." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq22952.pdf.

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Cherbuin, Nicolas. "Hemispheric interaction : when and why is yours better than mine? /." View thesis entry in Australian Digital Theses Program, 2005. http://thesis.anu.edu.au/public/adt-ANU20060317.135525/index.html.

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Bermudez, Patrick. "Sexual dimorphism in the corpus callosum : methodological considerations in MRI morphometry." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=31195.

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Studies of sexual dimorphism in the corpus callosum (CC) have employed a variety of methodologies for measurement and normalization but have yielded disparate results. The present work demonstrates how in some cases different manipulations of the same raw data, corresponding to different commonly used methodologies, produce discordant results. Midsagittal CC area was measured from magnetic resonance images (MRIs) of 137 young normal volunteers. Three strategies intended to normalize for average differences in brain size between the sexes, as well as five different normalization variables, were contrasted and evaluated. The stereotaxic method normalizes for inter-subject differences in overall brain size by scaling MRIs into a standardized space. The ratio method uses one of five different indices of brain size and divides it into CC area. The covariate method uses one of these indices as a covariate in statistical analyses. Male subjects show significantly larger absolute total area, as well as anterior third and posterior midbody. However, in 2 of 3 normalization strategies, namely the stereotaxic and ratio methods, females show relatively larger total area, anterior midbody and splenium. The covariate method did not show any significant differences at the .05 level. Results suggest that different approaches to normalization and analysis are not necessarily equivalent and interchangeable.
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Books on the topic "Corpus callosum"

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Turgut, Mehmet, R. Shane Tubbs, Ahmet Tuncay Turgut, and Cuong C. J. Bui, eds. The Corpus Callosum. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-38114-0.

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G, Reeves Alexander, and Roberts David W, eds. Epilepsy and the corpus callosum. New York: Plenum, 1995.

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Reeves, Alexander G., ed. Epilepsy and the Corpus Callosum. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4613-2419-5.

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G, Reeves Alexander, and Dartmouth Conference on the Corpus Callosum and Epilepsy (1st : 1982 : Hanover, N.H.), eds. Epilepsy and the corpus callosum. New York: Plenum Press, 1985.

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Cenzato, Marco. Large AVM of the corpus callosum. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-98390-1.

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Reeves, Alexander G., and David W. Roberts, eds. Epilepsy and the Corpus Callosum 2. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-1427-9.

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Maryse, Lassonde, Jeeves Malcolm A. 1926-, and International Brain Research Organization, eds. Callosal agenesis: A natural split brain? New York: Plenum Press, 1994.

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Agenesis of the corpus callosum: The beast within. [Place of publication not identified]: iUniverse Inc., 2010.

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Tappe, Heike. Der Spracherwerb bei Corpus-Callosum-Agenesie: Eine explorative Studie. Tübingen: G. Narr, 1999.

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Tappe, Heike. Der Spracherwerb bei Corpus-Callosum-Agenesie: Eine explorative Studie. Tübingen: G. Narr, 1999.

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Book chapters on the topic "Corpus callosum"

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Dupree, Jeff. "Corpus Callosum." In Encyclopedia of Clinical Neuropsychology, 966–67. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-57111-9_308.

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McLellan, Tracey. "Corpus Callosum." In Encyclopedia of Child Behavior and Development, 421–22. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-0-387-79061-9_705.

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Dupree, Jeff. "Corpus Callosum." In Encyclopedia of Clinical Neuropsychology, 1–2. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-56782-2_308-2.

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Hegarty, John P., Antonio Y. Hardan, and Thomas W. Frazier. "Corpus Callosum." In Encyclopedia of Autism Spectrum Disorders, 1–3. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4614-6435-8_669-3.

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Frazier, Thomas, and Antonio Hardan. "Corpus Callosum." In Encyclopedia of Autism Spectrum Disorders, 802–3. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1698-3_669.

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Hegarty, John P., Antonio Y. Hardan, and Thomas Frazier. "Corpus Callosum." In Encyclopedia of Autism Spectrum Disorders, 1204–6. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-91280-6_669.

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Dupree, Jeff. "Corpus Callosum." In Encyclopedia of Clinical Neuropsychology, 709. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-0-387-79948-3_308.

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Glickstein, Mitchell. "Corpus Callosum: History." In Epilepsy and the Corpus Callosum 2, 1–10. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-1427-9_1.

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Roberts, David W. "Corpus callosum operations." In The Treatment of Epilepsy, 895–902. Oxford, UK: John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781118936979.ch70.

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McCormack, Erin, Ryan Glynn, and R. Shane Tubbs. "Surgical Techniques for Callosal Disconnection." In The Corpus Callosum, 131–38. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-38114-0_13.

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Conference papers on the topic "Corpus callosum"

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El Munim, Hossam E. Abd, and Aly A. Farag. "Elastic Registration of the Corpus Callosum." In 2007 IEEE International Conference on Image Processing. IEEE, 2007. http://dx.doi.org/10.1109/icip.2007.4379844.

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Farag, A., S. Elhabian, M. Abdelrahman, J. Graham, A. Farag, Dongqing Chen, and M. F. Casanova. "Shape modeling of the corpus callosum." In 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2010). IEEE, 2010. http://dx.doi.org/10.1109/iembs.2010.5626169.

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Zhu, Alyssa H., Arvin Saremi, Armand Amini, Ricardo Pires, Paul M. Thompson, and Neda Jahanshad. "Robust automatic corpus callosum analysis toolkit: mapping callosal development across heterogeneous multisite data." In 14th International Symposium on Medical Information Processing and Analysis, edited by Eduardo Romero, Natasha Lepore, and Jorge Brieva. SPIE, 2018. http://dx.doi.org/10.1117/12.2506661.

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Kovac, Thomas, Sammy Rogmans, and Frank Van Reeth. "Computing Corpus Callosum as Biomarker for Degenerative Disorders." In International Conference on Computer Vision Theory and Applications. SCITEPRESS - Science and and Technology Publications, 2015. http://dx.doi.org/10.5220/0005310201380149.

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Zielmann, ML, B. Eger, J. Dinger, C. Birdir, and M. Rüdiger. "Diagnostischer Algorithmus für Corpus callosum Agenesie bei Neugeborenen." In 29. Deutscher Kongress für Perinatale Medizin. Deutsche Gesellschaft für Perinatale Medizin (DGPM) – „Hinterm Horizont geht's weiter, zusammen sind wir stark“. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3401256.

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Ayers, Brandon, Eileen Luders, Nicolas Cherbuin, and Shantanu H. Joshi. "Corpus callosum thickness estimation using elastic shape matching." In 2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI 2015). IEEE, 2015. http://dx.doi.org/10.1109/isbi.2015.7164166.

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Cover, Giovana S., Simone Appenzeller, Letícia Rittner, and Mariana Eugênia de Carvalho Pereira. "Corpus callosum parcellation methods: a quantitative comparative study." In Biomedical Applications in Molecular, Structural, and Functional Imaging, edited by Barjor Gimi and Andrzej Krol. SPIE, 2018. http://dx.doi.org/10.1117/12.2296617.

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Raile, Vera, Nina Herz, Gabriel Promnitz, Joanna Schneider, and Angela Maria Kaindl. "Clinical Outcome of Children with Corpus Callosum Agenesis." In Abstracts of the 45th Annual Meeting of the Society for Neuropediatrics. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1698176.

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Ibrahim, Shafaf, Nur Aina Shahirah Mat Jelaini, Nor Azura Md Ghani, Roziah Mohd Janor, and Mohd Hanafi Ali. "Age Differences Classification Associated with Corpus Callosum Measurement." In 2022 IEEE International Conference on Computing (ICOCO). IEEE, 2022. http://dx.doi.org/10.1109/icoco56118.2022.10031802.

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Silvério, Gabriel André, Isabela Louise Weber, Renata Cristine Alves, Pedro Arthur Possan, Mateus Pinto Marchetti, Vera Cristina Terra, Karen Luiza Ramos Socher, Nancy Watanabe, and Carlos Cesar Conrado Caggiano. "Cytotoxic lesion of the corpus callosum associated with Tumor Lysis Syndrome." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.538.

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Case presentation: MCP, 39 years, female, with primary rectal cancer with lung metastases being treated with weekly cycles of chemotherapy, without other comorbidities. At the end of 46 hours of another cycle of this treatment, patient presented an episode of weakness associated with release of the sphincters, without clonism. Physical examination with stable vital signs, closed eyelids, non-contacting and glasgow coma scale (GCS) 10. Laboratory tests with hypocalcemia, uremia, hyperphosphatemia, increased creatinine, hypomagnesemia, hyperuricemia. On the following day she underwent hemodialysis and evolves with improvement in the level of consciousness (GCS 14), communicative, mild confusion and anterograde amnesia. No alteration at neurological examination. cranioencephalic magnetic resonance imaging with contrast demonstrating signs of diffusion restriction in the splenium region of the corpus callosum. With this, it was possible to determine the diagnosis of cytotoxic lesions of the corpus callosum (CLOCCS) due to tumor lysis syndrome. Discussion: CLOCCs are secondary lesions associated with varied etiologies, including drug therapy, malignancy, metabolic abnormalities (e.g. electrolyte imbalance) and infections. Cell-cytokine interactions lead to massively increased levels of cytokines and extracellular glutamate, resulting in dysfunction of callosal neurons and microglia, and cytotoxic edema develops as water becomes trapped whitin the cells. CLOCCs appears in magnetic resonance imaging as areas of increased signal intensity on FLAIR and low diffusion on diffusion weighted. This lesion is usually midline, reversible and symmetric. Conclusion: It is important to know the radiographic features of CLOCCS and theirs known causes, so the source can be found and addressed and avoid misdiagnosis of primary colossal conditions.
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Reports on the topic "Corpus callosum"

1

Tarpley, R. J., and S. H. Ridgway. Corpus Callosum Size in Deiphinid Cetaceans. Fort Belvoir, VA: Defense Technical Information Center, December 1994. http://dx.doi.org/10.21236/ada292863.

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2

Kostadinova, Ivanka, Boycho Landzhov, Nikolay Danchev, Lyubomir Vezenkov, and Alexander Oskar. Effect of 4-Amino-pyridine and Newly Synthesized Original 4-Aminopyridine Derivatives on Cuprizoneinduced Demyelination of Corpus Callosum in Mice. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, August 2020. http://dx.doi.org/10.7546/crabs.2020.08.13.

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