Academic literature on the topic 'Coronary heart disease Complications Prevention'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Coronary heart disease Complications Prevention.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Coronary heart disease Complications Prevention"

1

Alpert, Joseph S. "Coronary Heart Disease: Prevention, Complications, and Treatment." JAMA: The Journal of the American Medical Association 253, no. 24 (June 28, 1985): 3609. http://dx.doi.org/10.1001/jama.1985.03350480119039.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Kirichenko, A. A. "Coronary heart disease and inflammation." Clinical Medicine (Russian Journal) 96, no. 8 (December 20, 2018): 688–95. http://dx.doi.org/10.18821/0023-2149-2018-96-8-688-695.

Full text
Abstract:
The increased content of inflammation markers in the blood is a significant prognostic sign of coronary events in persons with stable or asymptomatic course of coronary heart disease (CHD) and suggests that the inflammation underlying the destabilization of CHD has an independent character and is largely independent of the severity of stenotic lesions of coronary vessels. Activation of the local inflammatory process in the atherosclerotic plaque leads to the destruction of the fibrous capsule in combination with an increase in the activity of cellular and plasma factors of the coagulation system and inhibition of the fibrinolytic system. Cytomegalovirus, Chlamydia pneumoniae, pathogens of periodontal disease are nominated for the role of inducers of inflammatory reactions. The synergistic effect of several pathogens is reflected in the concept of burden of infection (“infectious burden”). Immuno-inflammatory rheumatic diseases are characterized by a high risk of cardiovascular complications. An important place in their prevention is an effective anti-inflammatory therapy: methotrexate, suppressing the formation of interleukin 1ft and tumor necrosis factor a, allows not only to modify the course of the disease, but also to reduce the risk of cardiovascular accidents. Chronic inflammation, as a key element of atherosclerosis pathogenesis, can be caused not only by infectious and immune factors, but also by metabolic factors. The activation of inflammasomes induced by cholesterol crystals in macrophages is an important link between cholesterol metabolism and inflammation in atherosclerotic plaques. Confirmation of the important pathogenetic role of inflammation is to reduce the risk of cardiovascular complications (CVD) on the background of anti-inflammatory therapy. In statin therapy, the decrease in The level of C-reactive protein (CRP) was significantly correlated with the suppression of atherosclerosis progression and a decrease in the risk of SSR, regardless of the degree of lowering the low-density lipoprotein cholesterol level. Taking colchicine in a low dose in patients with stable coronary artery disease, who received standard therapy, reduced the risk of acute coronary syndrome and sudden cardiac death. Secondary prevention of cardiovascular complications by human monoclonal antibodies to interleukin 1ft (kanakinumab) led to a decrease in the risk of SSR regardless of sex, Smoking, and lipid levels.
APA, Harvard, Vancouver, ISO, and other styles
3

Ivanova, Anastasia S., and Maxim L. Kasyanik. "Effect of Catecholamines on Haemostasis Indicators in Coronary Heart Disease." Bulletin of Rehabilitation Medicine 21, no. 3 (June 30, 2022): 129–36. http://dx.doi.org/10.38025/2078-1962-2022-21-3-129-136.

Full text
Abstract:
The concentration of catecholamines, having positive inotropic and chronotropic effects on heart function, increases under the action of strong stimuli. This mechanism of influence is very important in terms of the development of both coronary and non-coronary myocardial damage. However, further studies have revealed an important role of catecholamines in the regulation of hemostasis processes, which is very relevant in patients with coronary heart disease, as it increases the risk of myocardial infarction. Aim. Based on the literature data, to study the role of catecholamines in the regulation of the hemostasis system as a risk factor for complications in coronary heart disease. Material and methods. We analyzed literature sources in the computer databases «Cyberlennica», «PubMed», «eLibrary» using the search words: «сatecholamines – hemostasis», «сatecholamines – platelets», «сatecholamines – leukocytes», «coronary heart disease – сatecholamines», «coronary heart disease – hemostasis», «coronary heart disease – platelets». The analyzed literature describes the results of original studies that characterize the multifactorial influence of catecholamines on the hemostasis system in the coronary heart disease: the effects of these hormones as an important activator of the platelet hemostasis, the role of platelets in activating the coagulation component of hemostasis and its specific features, the importance of leukocytes, erythrocytes, endothelium, changes in the lipid profile in disorders of the blood coagulation process. Therefore, regular monitoring of its condition, timely pharmacological correction is necessary to ensure effective relapse prevention and reduce the risk of complications and fatal outcome. Conclusion. Regular monitoring of the hemostasis system and timely pharmacological correction are necessary to ensure effective relapse prevention and reduce the risk of complications and fatal outcome in patients with coronary heart disease.
APA, Harvard, Vancouver, ISO, and other styles
4

Vogralik, V. G., M. T. Saltseva, N. V. Amineva, and V. I. Klemenov. "Value of antithrombotic therapy in patients with coronary heart disease." Kazan medical journal 69, no. 5 (October 15, 1988): 341–43. http://dx.doi.org/10.17816/kazmj98431.

Full text
Abstract:
Numerous studies have shown that intravascular thrombosis is one of the main causes of death in patients with coronary heart disease. Therefore, the issues of prevention of thromboembolic complications and development of the tactics of differentiated antithrombotic therapy in coronary heart disease, including chronic forms of the disease, are extremely relevant.
APA, Harvard, Vancouver, ISO, and other styles
5

Aquarista, Nindara Citra. "Differences Characteristics Patients Diabetes Mellitus Type 2 with and without Coronary Heart Disease." Jurnal Berkala Epidemiologi 5, no. 1 (April 28, 2017): 37. http://dx.doi.org/10.20473/jbe.v5i1.2017.37-47.

Full text
Abstract:
Diabetes mellitus is the third highest Non-Communicable Diseases (NCDs), which causes death in Indonesia. The incidence of coronary heart disease in diabetes mellitus is high, 65% of people with diabetes mellitus die due to coronary heart disease and stroke. The purpose of this study is to analyze the differences in the characteristics of Diabetes mellitus type 2 in patients with and without coronary heart disease in Haji General Hospital Surabaya year 2016. This research uses observational analysis with cross sectional study design.The subject of the study is the incidence of diabetes Mellitus type 2 with and without coronary heart disease with undergoing outpatient treatment at Haji General Hospital Surabaya year 2016. The Samples were taken by fixed-disease sampling method with 42 people as the samples. The data analysis uses Chi Square test. The results show for the independent variables that have the most significant difference inHaji General Hospital Surabaya year 2016 is smoking behavior (p = 0.00; PR = 7.85; 95% CI = 2.09 to 29.50) and hypertension (p= 0,002; PR = 3.51; 95% CI = 1.42 to 8.67). In conclusion, the smoking behavior and hypertension can lead to complications of coronary heart disease for patients with type in Diabetes Mellitus type 2 in Haji General Hospital year 2016. It needs awareness to check blood pressure regularly and eliminate the smoking habit as the prevention of complications of coronary heart disease for patients with diabetes mellitus type 2.Keywords: diabetes mellitus type 2, coronary hearth disease.
APA, Harvard, Vancouver, ISO, and other styles
6

Aquarista, Nindara Citra. "Differences Characteristics Patients Diabetes Mellitus Type 2 with and without Coronary Heart Disease." Jurnal Berkala Epidemiologi 5, no. 1 (April 28, 2017): 37. http://dx.doi.org/10.20473/jbe.v5i12017.37-47.

Full text
Abstract:
Diabetes mellitus is the third highest Non-Communicable Diseases (NCDs), which causes death in Indonesia.The incidence of coronary heart disease in diabetes mellitus is high, 65% of people with diabetes mellitus die due to coronary heart disease and stroke. The purpose of this study is to analyze the differences in the characteristics of Diabetes mellitus type 2 in patients with and without coronary heart disease in Haji General Hospital Surabaya year 2016. This research uses observational analysis with cross sectional study design. The subject of the study is the incidence of diabetes Mellitus type 2 with and without coronary heart disease with undergoing outpatient treatment at Haji General Hospital Surabaya year 2016. The Samples were taken by fixed-disease sampling method with 42 people as the samples. The data analysis uses Chi Square test. The results show for the independent variables that have the most significant difference inHaji General Hospital Surabaya year 2016 is smoking behavior (p = 0.00; PR = 7.85; 95% CI = 2.09 to 29.50) and hypertension (p = 0,002; PR = 3.51; 95% CI = 1.42 to 8.67). In conclusion, the smoking behavior and hypertension can lead to complications of coronary heart disease for patients with type in Diabetes Mellitus type 2 in Haji General Hospital year 2016. It needs awareness to check blood pressure regularly and eliminate the smoking habit as the prevention of complications of coronary heart disease for patients with diabetes mellitus type 2.Keywords: diabetes mellitus type 2, coronary hearth disease.
APA, Harvard, Vancouver, ISO, and other styles
7

Taratukhin, E. O. "Arterial hypertension and coronary heart disease: the place of angiotensin II receptor antagonists." Cardiovascular Therapy and Prevention 11, no. 6 (December 20, 2012): 78–80. http://dx.doi.org/10.15829/1728-8800-2012-6-78-80.

Full text
Abstract:
The paper considers arterial hypertension and coronary heart disease as pathologies which share multiple pathogenetic mechanisms. The role of angiotensin II receptor antagonists (ARA) in the effective treatment of these diseases and in prevention of their complications is discussed. The modern views on ARA and their indications are presented.
APA, Harvard, Vancouver, ISO, and other styles
8

Budi Yuli Setianto and Andika Putra. "Radiation-Induced Heart Disease: From Diagnosis to Prevention." ACI (Acta Cardiologia Indonesiana) 7, no. 1 (March 23, 2021): 31–35. http://dx.doi.org/10.22146/jaci.v7i1.544.

Full text
Abstract:
Radiotherapy has become an important component of multimodal treatment of malignancy. After 50 years, there was a drastic increase in outcomes of patients with malignancy. However, improvement of the survival is also accompanied by some inevitable complications on cardiovascular system which are often called radiation-induced heart disease (RIHD). RIHD comprises a spectrum of heart disease including pericardial disease, coronary artery disease, valvular heart disease, conduction system abnormalities, cardiomyopathy, and medium or large vessel vasculopathy. The underlying mechanisms include direct effects on function and structure of the heart, or accelerate development of cardiovascular disease, especially with the presence of previous cardiovascular risk factors. Recent studies have identified non-invasive methods for evaluation of RIHD. Furthermore, potential options preventing or at least attenuating RIHD have been developed. This review provides an overview of pathogenesis, clinical manifestation, diagnosis, management, and prevention of RIDH. Keywords: malignancy, radiotherapy, radiation - induced heart disease.
APA, Harvard, Vancouver, ISO, and other styles
9

Dąbrowski, Rafał. "Cardiological complications in the course of influenza and COVID-19." In a good rythm 1, no. 54 (April 30, 2020): 4–9. http://dx.doi.org/10.5604/01.3001.0014.1501.

Full text
Abstract:
Cardiac complications associated with the acute or chronic form of influenza and COVID-19 infection occur in < 10% of cases. They may affect pericardium, myocardium or coronary arteries which finally results in heart failure or in case of pericarditis – fluid in the pericardium and tamponade risk. A relationship has been demonstrated between influenza epidemics and an increased incidence of acute coronary syndromes. An important complication of influenza infection may be myocarditis and subsequent heart failure. Arrhythmias, in various forms and with varying degrees of severity, can occur at any stage of the disease. The possibility of sudden deaths in the course of influenza virus infection has been reported. The treatment of a patient with cardiovascular involvement should be multidirectional: causal, symptomatic and prophylactic in the aspect of heart failure prevention. The knowledge about cardiovascular complications in the course of SARS-CoV-2 infection is increasing. Despite the possibility of using antiviral drugs in treatment, prevention by vaccination still remains the most effective therapeutic method.
APA, Harvard, Vancouver, ISO, and other styles
10

Shafter, Ahmed M., Kashif Shaikh, Amit Johanis, and Matthew J. Budoff. "De-risking primary prevention: role of imaging." Therapeutic Advances in Cardiovascular Disease 15 (January 2021): 175394472110512. http://dx.doi.org/10.1177/17539447211051248.

Full text
Abstract:
Atherosclerotic cardiovascular disease (ASCVD) is a common disease among the general population, and includes four major areas: (1) coronary heart disease (CHD), manifested by stable angina, unstable angina, myocardial infarction (MI), heart failure, and coronary death; (2) cerebrovascular disease, manifested by transient ischemia attack and stroke; (3) peripheral vascular disease, manifested by claudication and critical limb ischemia; and (4) aortic atherosclerosis and aortic aneurysm (thoracic and abdominal). CHD remains the leading cause of death for both men and women in the United States. So, it is imperative to identify people at risk of CHD and provide appropriate medical treatment or intervention to prevent serious complications and outcomes including sudden cardiac death. Coronary artery calcification (CAC) is a marker of subclinical coronary artery disease. Therefore, coronary artery calcium score is an important screening method for Coronary artery disease (CAD). In this article, we performed a comprehensive review of current literatures and studies assessing the prognostic value of CAC for future cardiovascular disease (CVD) events. We searched PubMed, MEDLINE, Google Scholar, and Cochrane library. We also reviewed the 2018 American College of Cardiology (ACC)/American Heart Association (AHA) guideline on the assessment of CVD risk. A CAC score of zero corresponds to very low CVD event rates (∼1% per year) and hence a potent negative risk marker. This has been referred to as the ‘power of zero’ and affords the lowest risk of any method of risk calculation. It is now indicated in the 2018 ACC/AHA Cholesterol guidelines to be used to avoid statins for 5–10 years after a score of zero, and then re-assess the patient.
APA, Harvard, Vancouver, ISO, and other styles

Dissertations / Theses on the topic "Coronary heart disease Complications Prevention"

1

Bose, Jolly. "Percutaneous transluminal coronary angioplasty (PTCA) in the treatment of coronary artery disease in Hong Kong : procedural success, complications and long-term follow-up /." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B2084282X.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Leong, Yuk-yan Pauline, and 梁玉恩. "The effectiveness of exercise-based cardiac rehabilitation program for secondary prevention of coronary heart disease : a systematic review." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193828.

Full text
Abstract:
Objective: To examine the effect of exercise-based cardiac rehabilitation program for secondary prevention of coronary heart disease on cardiac-related mortality, recurrent cardiovascular event and quality of life. Methods: All studies published between 1990 and 2013 in PubMed, and from 1980 to 2013 in EMBASE, which evaluated the effectiveness of exercise-based cardiac rehabilitation program for coronary heart disease. Using the specific keywords “Cardiac rehabilitation”, “Coronary heart disease” OR “Ischemic heart disease” [MeSH], “Exercise” OR “Physical activities” AND “Quality of life” OR “Mortality” AND Cardiovascular events” were searched. A total of 7randomized controlled trials out of 5,051articles from PubMed and 117 articles from EMBASE were included in this systematic review. The primary outcome measures used in the included seven studies were HRQOL, restenosis, cardiac event, cardiac related mortality. Similar demographic and clinical characteristics of the subjects between the intervention and the control groups were recorded. The studies were from five countries. The average age of the subjects in the seven studies was 61years, the average half of them have history of myocardial infarction. Though there were discrepancies among the results generated in the included studies, the potential benefits of exercise-based cardiac rehabilitation could be seen. Results: Compared with the non-exercise-based cardiac rehabilitation, patients allocated to the exercise-based cardiac rehabilitation program had greater improvement in HRQOL and reduction of cardiac events. The result of reducing restenosis was inconsistent. The cardiac related mortality is not significant difference between exercise-based and non-exercise-based cardiac rehabilitation.
published_or_final_version
Public Health
Master
Master of Public Health
APA, Harvard, Vancouver, ISO, and other styles
3

Ashton, Emma Louise, and emma ashton@deakin edu au. "Effects of dietary constituents on coronary heart disease risk factors." Deakin University. School of Biological and Chemical Sciences, 2000. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20061207.153511.

Full text
Abstract:
Coronary Heart Disease (CHD) is a major cause of death in Western countries. Mediterranean and Asian populations have a lower risk of death from CHD compared to Westernised population, as do vegetarian versus omnivorous populations. Dietary constituents of traditional diets consumed by these populations are thought to influence both the classical risk factors for CHD, and the more recently identified risk factors, such as oxidative modification of low density lipoprotein (LDL), LDL particle size, arterial compliance and haemostatic factors. The aim of this thesis was to examine the effects of several food components, particularly soybean and monounsaturated fat (MUFA), on CHD risk factors through 3 carefully controlled dietary interventions, and a cross-sectional study. A randomised crossover dietary intervention study was conducted in 42 healthy males to investigate the effect on CHD risk factors of replacing lean meat with tofu, a soybean product regularly consumed by Asian populations, while controlling all other dietary factors. The tofu diet resulted in significantly lower total cholesterol and triacylglycerol levels compared to the lean meat diet, and LDL particles that were more resistant to in vitro oxidative modification. However, insulin, fibrinogen, factor VII, and lipoprotein (a) were not significantly different on the 2 diets. A postprandial study was subsequently conducted to investigate any acute effects of a tofu test meal on the oxidative modification of LDL in 16 male subjects. There was no significant difference between the susceptibility of LDL to oxidative modification before and after the tofu meal. Twenty eight healthy subjects completed a separate randomised crossover dietary intervention comparing a high MUFA fat diet, using an Australian high oleic sunflower oil, with a low fat, high carbohydrate diet on CHD risk factors. The high MUFA oil diet significantly increased high density lipoprotein cholesterol compared to the low fat diet as well as producing LDL that were more resistant to oxidative modification. Neither the size of the LDL particle nor arterial compliance were significantly different on the 2 diets. Twelve matched pairs of vegetations and omnivores were also studies to compare the habitual diet of a low and higher risk population group, to compare their risk factors and identify dietary constituents that may explain the differences. The vegetarians consumed less saturated fat (SFA) and dietary cholesterol while consuming more polyunsaturated fat, dietary fibre and vitamin E compared to omnivores. The vegetarians had lower total cholesterol, LDL cholesterol and triacylglycerol levels compared to the omnivores and had LDL particles that were more resistant to in vitro oxidation. These findings contribute to our knowledge about the dietary constituents that can alter some CHD risk factors in healthy subjects, and which could reduce the risk of developing CHD. Investigations in high risk groups might reveal even more benefits.
APA, Harvard, Vancouver, ISO, and other styles
4

Shaw, I., BS Shaw, and GA Brown. "Influence of strength training on cardiac risk prevention in individuals without cardiovascular disease." African Journal for Physical, Health Education, Recreation and Dance, 2009. http://encore.tut.ac.za/iii/cpro/DigitalItemViewPage.external?sp=1001650.

Full text
Abstract:
Abstract It has widely been shown that exercise, particularly aerobic exercise, has extensive cardioprotective benefits and is an important tool in the prevention of coronary heart disease (CHD). The present investigation aimed to determine the multivariate impact of strength training, designed to prevent the development of CHD, on the Framingham Risk Assessment (FRA) score. Twenty-eight healthy untrained men with low CHD risk (mean age 28 years and 7 months) participated in an eight-week (3- d/wk) strength training programme. Self-administered smoking records, resting blood pressures, total cholesterol (TC), high-density lipoprotein cholesterol (HDLC), FRA scores and absolute 10-year risks for CHD were determined at the pre-test and post-test. After the eight-week period, no significant (p > 0.05) differences were found in number of cigarettes smoked daily, systolic blood pressure, TC, HDLC, FRA scores and absolute 10-year risks for CHD in both the strength-trained (n = 13) and non-exercising control (n = 15) groups. The data indicate that strength training did not reduce the risk of developing CHD and absolute 10-year risk for CHD as assessed by the FRA score.
APA, Harvard, Vancouver, ISO, and other styles
5

Wrigley, Martha J. "Engaging families with a premature family history of heart disease : a primary prevention study for coronary heart disease." Thesis, University of Southampton, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485524.

Full text
Abstract:
This thesis focuses upon a preventative approach for people with a familial history of premature coronary heart disease. The research study had two aims; firstIy to understand the experience of individuals when their parent or sibling had been diagnosed with heart disease; secondly to develop and evaluate a primary prevention health promotion programme for these people. The thesis provides unique insight into their personal experiences of living with tIris familial diagnosis and gives details of how this population can be identified and involved successfully in a health promotion programme. The study was conducted in a district general hospital; 28 people were recruited of whom 20 participants completed the two year study. Narrative interviews were conducted at the beginning and end of the study, providing insight into people's personal experience. Salutogenesis is the theoretical framework in which the narratives are discussed; from these health resources are identified which can enhance people's progress and maintenance for a healthy lifestyle. The health promotion programme has established, developed and evaluated a nurseled and doctor supported primary pjevention strategy. Education and support was provided in the programme for individuals and families. The participants' physical and behavioural changes were reviewed six monthly, for two years. People are aware of risk factors associated with heart disease, but still seek professional support and advice in relation to their own lifestyle and behaviour. Individual lifestyle changes were achieved by most participants, which translated into significant findings for blood pressure and alcohol consumption; positive changes were seen in physical activity, smoking, diet and psychosocial stress. There were no improvements in lipid profiles. The need for a preventatiye approach in health care, which includes primordial and primary prevention for heart disease, is discussed. The issues in this thesis are reflective upon current government focus to develop preventative health services which actively engage with people as integral to this process. The thesis discusses coronary heart disease, the roles of prevention and health promotion, and identifies health resources for people at high-risk of future cardiovascular problems.
APA, Harvard, Vancouver, ISO, and other styles
6

Veroni, Margherita. "The use of pharmacotherapies in the secondary prevention of coronary heart disease." University of Western Australia. School of Population Health, 2006. http://theses.library.uwa.edu.au/adt-WU2006.0029.

Full text
Abstract:
[Truncated abstract] Background: This thesis examines pharmacotherapy use in the secondary prevention of coronary heart disease. It includes antiplatelet agents, beta-blockers, statins and ACE inhibitors, all shown in landmark clinical trials and meta-analyses to reduce the risk of cardiac events in patients with known coronary disease. Underuse of effective preventive therapies represents a lost opportunity to reduce mortality and morbidity. Overseas studies have shown significant underuse of effective therapies at the time of hospital discharge following an acute event and later in ambulatory care. Australian data on prescribing practices following an acute coronary event and, ongoing use in ambulatory care are sparse. Aims: The aim of this thesis was to quantify the prescription of known effective therapies at the time of hospital discharge following an acute coronary event and ongoing use in ambulatory care. A secondary aim was to identify barriers to optimal secondary prevention thus providing an evidential basis to recommend change. Methods: This was an observational study of a cohort of post-MI patients admitted to a tertiary and affiliate hospital in Perth, Western Australia. The continuum of care from the treatment plan at discharge through to the treatment regimen and risk factor management 12 months post-MI was examined. The intermediate step, communication about the treatment plan with the patient and the primary health care provider was also examined. The study involved a review of hospital medical records and follow-up questionnaires to patients and their general practitioners at 3 and 12 months post-MI. All post-myocardial patients were included in the analysis of prescriptions at discharge. The follow-up study included patients 80 years and younger with no terminal conditions. Patient interviews at 3 months and interviews and focus groups with key hospital staff provided qualitative data to inform the quantitative data.
APA, Harvard, Vancouver, ISO, and other styles
7

Rees, Lois. "The provision of disease prevention services from community pharmacies." Thesis, University College London (University of London), 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339279.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Ревенко, Жанетта Анатоліївна, and Рохіт Тхакур. "Quality of life determination in patients with coronary heart disease in various forms of this disease complications." Thesis, «Хист», Всеукраїнський медичний журнал студентів і молодих вчених. – 2016, випуск 18. – 690 с, 2016. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/10620.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Lalonde, Lyne. "Health-related quality of life measures in coronary heart disease prevention and treatment." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0006/NQ44484.pdf.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Khatib, R. "Adherence to secondary prevention medicines by coronary heart disease patients : first reported adherence." Thesis, University of Bradford, 2012. http://hdl.handle.net/10454/5484.

Full text
Abstract:
Background Non-adherence to evidence based secondary prevention medicines (SPM) by coronary heart disease (CHD) patients limits their expected benefits and may result in a lack of improvement or significant deterioration in health. This study explored self-reported non-adherence to SPM, barriers to adherence, and the perception that patients in West Yorkshire have about their medicines in order to inform practice and improve adherence. Methods In this cross-sectional study a specially designed postal survey (The Heart Medicines Survey) assessed medicines-taking behaviour using the Morisky Medicines Adherence 8 items Scale (MMAS-8), a modified version of the Single Question Scale (SQ), the Adherence Estimator (AE), Beliefs about Medicines Questionnaire(BMQ) and additional questions to explore practical barriers to adherence. Patients were also asked to make any additional comments about their medicines-taking experience. A purposive sample of 696 patients with long established CHD and who were on SPM for at least 3 months was surveyed. Ethical approval was granted by the local ethics committee. Results 503 (72%) patients participated in the survey. 52%, 34% and 11% of patients were prescribed at least four, three and two SPMs respectively. The level of non-adherence to collective SPM was 44%. The AE predicted that 39% of those had an element of intentional non-adherence. The contribution of aspirin, statins, clopidogrel, beta blockers, angiotensin converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARBs) to overall non-adherence as identified by the SQ scale was 62%, 67%, 7%, 30%, 22% and 5%, respectively. A logistic regression model for overall non-adherence revealed that older age and female gender were associated with less non-adherence (OR = 0.96, 95% CI: 0.94, 0.98; OR = 0.56, 95% CI: 0.34, 0.93; respectively). Specific concern about SPM, having issues with repeat prescriptions and aspirin were associated with more non-adherence (OR = 1.12, 95% CI: 1.07, 1.18; OR = 2.48, 95% CI: 1.26, 4.90, OR = 2.22, 95% CI: 1.18, 4.17). Other variables were associated with intentional and non-intentional non-adherence. 221 (44%) patients elaborated on their medicines-taking behaviour by providing additional comments about the need for patient tailored information and better structured medicines reviews. Conclusions The Medicines Heart Survey was successful in revealing the prevalence of self-reported non-adherence and barriers to adherence in our population. Healthcare professionals should examine specific modifiable barriers to adherence in their population before developing interventions to improve adherence. Conducting frequent structured medicines-reviews, which explore and address patients' concerns about their medicines and healthcare services, and enable them to make suggestions, will better inform practice and may improve adherence.
APA, Harvard, Vancouver, ISO, and other styles

Books on the topic "Coronary heart disease Complications Prevention"

1

Stent thrombosis: Epidemiology, prevention, and management. Hauppauge, N.Y: Nova Science, 2011.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

1946-, Frishman William H., ed. Medical management of lipid disorders: Focus on prevention of coronary artery disease. Mount Kisco, NY: Futura, 1992.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

1969-, Fernandez Sandra, ed. The myth of cholesterol: Dispelling the fear and creating real heart health. Ann Arbor, MI: MCD Century Publications, 2005.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

Kristen, Strom Terry, and Fox Barry, eds. Syndrome X: Overcoming the silent killer that can give you a heart attack. New York: Simon and Schuster, 2000.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
5

1943-, Williams Christine L., Wynder Ernst L. 1922-, and New York Academy of Sciences., eds. Hyperlipidemia in childhood and the development of atherosclerosis. New York, N.Y: New York Academy of Sciences, 1991.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

S, Dhalla Naranjan, ed. Myocardial ischemia and preconditioning. Boston: Kluwer Academic, 2003.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
7

Brown, Don. Hyperlipidemia and prevention of coronary heart disease. Seattle, WA: Natural Product Research Consultants, 1997.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

Authority, Northumberland Health. Northumberland coronary heart disease prevention strategy: 1992. Morpeth: Northumberland Health Authority, 1992.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
9

Royal Colleges of Physicians of the United Kingdom. Committee on Health Promotion. Coronary heart disease prevention: Putting it intopractice. London: Faculty of Public Health Medicine of the Royal Colleges of Physicians of the United Kingdom, 1990.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
10

Pain, Charles Hawkhurst. Coronary heart disease prevention: An ecological approach. Manchester: University of Manchester, 1990.

Find full text
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Coronary heart disease Complications Prevention"

1

de Lorgeril, Michel, and Patricia Salen. "Secondary Prevention of Coronary Heart Disease: Impact of Nutrition on the Risk of Fatal Complications and Importance of the Concept of Omega-3 Deficiency." In Cardiovascular Prevention and Rehabilitation, 181–93. London: Springer London, 2007. http://dx.doi.org/10.1007/978-1-84628-502-8_23.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Vlodaver, Zeev, and Robert F. Wilson. "Complications of Acute Myocardial Infarction." In Coronary Heart Disease, 321–47. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4614-1475-9_18.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Duprez, Daniel. "Prevention of Coronary Artery Disease." In Coronary Heart Disease, 497–508. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4614-1475-9_29.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Sherazi, Saadia, and Robert Block. "Coronary Artery Disease Prevention." In Manual of Heart Failure Management, 17–32. London: Springer London, 2009. http://dx.doi.org/10.1007/978-1-84882-185-9_2.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Mulcahy, R. "The Role of the General Practitioner in the Prevention of Coronary Heart Disease." In Coronary Heart Disease, 27–57. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-010-9218-0_2.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

de Lorgeril, Michel, and Patricia Salen. "Dietary Prevention of Coronary Heart Disease." In Wild-Type Food in Health Promotion and Disease Prevention, 227–42. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-330-1_17.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Schaefer, Ernst J., and Mariko Tani. "Nutrition and Coronary Heart Disease Prevention." In Dyslipidemias, 329–41. Totowa, NJ: Humana Press, 2015. http://dx.doi.org/10.1007/978-1-60761-424-1_19.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Patel, C. "Prevention Paradox in Coronary Heart Disease." In Biological and Psychological Factors in Cardiovascular Disease, 533–49. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71234-0_34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

von der Lohe, Elisabeth. "Primary and Secondary Prevention of Coronary Heart Disease." In Coronary Heart Disease in Women, 145–74. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-55553-4_8.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Rose, G. "Social Class and Coronary Heart Disease." In Primary and Secondary Prevention of Coronary Heart Disease, 44–49. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70296-9_4.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Coronary heart disease Complications Prevention"

1

Kolyaskina, M. M., A. A. Kislyakova, and P. Sh Osmanova. "EMPLOYEES OPERATING AND MAINTAINING WIRED AND WIRELESS COMMUNICATION DEVICES CARDIOVASCULAR RISK DEVELOPMENT MONITORING." In The 4th «OCCUPATION and HEALTH» International Youth Forum (OHIYF-2022). FSBSI «IRIOH», 2022. http://dx.doi.org/10.31089/978-5-6042929-6-9-2022-1-124-127.

Full text
Abstract:
Introduction: Heart disease has been the leading cause of death in the world for the past 20 years. The main pathogenetic mechanism leading to the development of coronary disease and fatal complications is atherosclerosis. The goal of study is to assess cardiovascular risks in workers operating and maintaining communication facilities based on wired and wireless technologies. Materials and methods: 50 employees operating in the field of communications based on wired and wireless technologies health state survey was carried out. Lipid metabolism parameters were assessed, the risks of cardiovascular complications were calculated by SCORE and ASCORE scales, and «Vascular age» was determined. Results: High cardiovascular risk was detected in 40% of examined patients. Elevated values of atherogenic index were already observed in middle-aged people (45-60years). Assessment of SCORE and ASCORE scales revealed a high risk of cardiovascular complications development in middle-aged and elderly people. An excess of vascular age compared to real one in 45-60 years and 61-74 years by an average of 7 (p<0.001) and 5 (p=0.026) years, respectively, was established. Conclusion: The most pronounced changes were found in people of working age (45-60 years). Thus, it is necessary to develop preventive measures aimed to cardio screening with of early signs of health disorders detection, to prevent the development of cardiovascular complications and groups at increased risk of diseases formation.
APA, Harvard, Vancouver, ISO, and other styles
2

Poniewierski, M., M. Barthels, and H. Poliwoda. "THE SAFETY AND EFFICACY OF A LOW MOLECULAR WEIGHT HEPARIN (FRAGMIN) IN THE PREVENTION OF DEEP VEIN THROMBOSIS IN MEDICAL PATIENTS: A RANDOMIZED DOUBLE-BLIND TRIAL." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643224.

Full text
Abstract:
The safety and efficacy of 2500 anti-Factor Xa U of a low molecular weight heparin (Kabi 2165, Fragmin) subcutaneously once a day, and 5000 IU of standard unfractionated Heparin (KabiVitrum, Stockholm) subcutaneously twice daily as thromboprophylaxis was compared in 200 medical patients in a randomized double blind trial. According to the risk of DVT the patients were stratified before randomization in a high and low risk group. The high risk group consisted of 100 patients mainly with malignant diseases and/or previous history of thromboembolism, the low risk group of 100 patients with mainly myocardial infarction and/or coronary heart disease. The prophylaxis was given for seven to ten days. In 192 consecutive patients the clinical status and thermographic screening for DVT (leg temperature profiles, DeVeTherm) were daily evaluated. In two cases of suspected DVT and one case of suspected PE, the following phlebography or pulmonary scintigraphy were found to be negative. In the high risk group, one patient treated with Fragmin having a central venous catheter developed on day 10 symptoms of an arm vein thrombosis. There were no bleeding complications observed in either of the two treatment groups. Two patients with trombocytopenia (25.000 and 22.000/pl) due to chemotherapy and underlying malignant disease were successfully treated with Fragmin without developing any bleeding complications. In eight patients during Fragmin prophylaxis invasive diagnostic methods as heart catheterization, gastroscopy, bronchoscopy or spinal puncture were performed without noticing any bleeding events. 2500 anti-Factor Xa U of Fragmin gave plasma levels by anti-Factor Xa assay (S-2222, Kabi) of mean 0,1 U/ml when blood was sampled three to four hours after the subcutaneus application. There was no accumulation during the treatment periode observed.This study suggests that 2500 anti-Factor Xa U of Fragmin once daily is as safe and effective as 5000 IU of standard heparin twice daily in these medical patients. Especially in patients who need prophylaxis for a long time eg. with malignant disease, the once daily injection is welcomed.
APA, Harvard, Vancouver, ISO, and other styles
3

Holm, Jukka, Reijo Laaksonen, Paul Dendale, Cindel Bonneux, and Martijn Scherrenberg. "Creating Audio-Visual Content for a Personalized Prevention Programme in Coronary Heart Disease." In 2022 26th International Conference Information Visualisation (IV). IEEE, 2022. http://dx.doi.org/10.1109/iv56949.2022.00070.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Giardina, Marisol, Francisco Azuaje, Paul McCullagh, and Roy Harper. "A Supervised Learning Approach to Predicting Coronary Heart Disease Complications in Type 2 Diabetes Mellitus Patients." In Sixth IEEE Symposium on BioInformatics and BioEngineering (BIBE'06). IEEE, 2006. http://dx.doi.org/10.1109/bibe.2006.253297.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Ono, Kensuke, Ken Yamamoto, Takahiro Tsukahara, Masahiro Motosuke, Hiroyoshi Kawamoto, Satoko Tahara, Kentaro Tanaka, and Sunao Nakamura. "Flow Measurement in Stented Left Coronary Artery Models." In ASME-JSME-KSME 2019 8th Joint Fluids Engineering Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/ajkfluids2019-5154.

Full text
Abstract:
Abstract Ischemic heart disease, a generic term for angina pectoris and myocardial infarction, is caused by blood flow failure due to a lesion generated in the coronary artery of the heart. Because the ischemic heart disease causes fatal problems, a stent placement technique called the percutaneous coronary intervention (PCI) is frequently performed to expand coarctated arteries to recover the function. However, although the PCI technique is a less-invasive technique, there is a risk of complications such as stent thrombosis and restenosis due to the placed stent. In order to understand the cause and the mechanism of the complications, effects of the stent placement and the stent shape on the blood flow is experimentally investigated. Silicone left coronary artery models were prepared to perform particle tracking velocimetry (PTV) and calculated the wall shear stress (WSS). The measurement results show that the flow structure and the WSS are changed depending on the deformation of the stent and the location of the placed stent.
APA, Harvard, Vancouver, ISO, and other styles
6

Kim, Jinsoo, Ciaran O’Neill, Kavya Pathak, Sai Shanthanand Rajagopal, Martina Moyne, Glen Picard, J. Andrew Taylor, and Conor Walsh. "Automatically Triggered FES Rowing Device for SCI Patients With Motorized Return." In 2018 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/dmd2018-6824.

Full text
Abstract:
A quarter of a million people in the United States are affected by spinal cord injury (SCI), which causes loss of sensation and muscle function. Improvements in clinical care have resulted in a lower risk of mortality from initial complications like bedsores or urosepsis, though patients are more susceptible to long term conditions like coronary heart disease [1], which is a leading cause of death for SCI patients [2]. Patients with SCI have sedentary lifestyles, decreased aerobic fitness, and limited levels of oxygen uptake, which contribute to increased rates of cardiovascular complications [2]. To mitigate these factors, SCI patients must perform vigorous aerobic exercise, which can be done through functional electrical stimulation (FES) [3].
APA, Harvard, Vancouver, ISO, and other styles
7

Aronis, Ze’ev, Erez Kanka, Eyass Massarwa, Rami Haj-Ali, and Shmuel Einav. "Influence of Microcalcifications on Stress Development Within a Vulnerable Plaque’s Cap." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53197.

Full text
Abstract:
Vulnerable plaques are inflamed, active, and growing lesions which are prone to complications such as rupture, luminal and mural thrombosis, intraplaque hemorrhage, and rapid progression to stenosis. Despite major advances in the prevention and treatment of this disease, it remains the leading cause of morbidity and mortality worldwide, accounting for 30% of all deaths globally [1]. The importance of stress/strain distribution is now well recognized in vascular pathophysiology, specifically in the mechanisms of plaque rupture. Finite element modeling (FEM) and advanced fluid structure interaction (FSI) studies can better characterize coronary stenosis coupling constitutive equations. Mechanical factors such as stress concentrations within a plaque (material fatigue), lesion characteristic (location, size, and composition), and flow patterns are involved in rupture of plaques. Assessment of local mechanical characteristics caused by plaque structure is important for identifying vulnerable plaques and may improve final estimation of the risk for coronary syndrome.
APA, Harvard, Vancouver, ISO, and other styles
8

Aronis, Ze’ev, and Shmuel Einav. "Analysis of Biomechanical Forces Influencing Atherosclerotic Plaque Vulnerability." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206454.

Full text
Abstract:
Cardiovascular disease has long been the leading cause of death in the western world: over 1.4 million heart attacks are suffered every year, more than half of which prove fatal. Vulnerable plaques are inflamed, active, and growing lesions which are prone to complications such as rupture, luminal and mural thrombosis, intraplaque hemorrhage, and rapid progression to stenosis. The rupture of thin fibrous cap overlying the necrotic core of a vulnerable plaque is the principal cause of acute coronary syndrome. The mechanism or mechanisms responsible for the sudden conversion of a stable atherosclerotic plaque to a life threatening athero-thrombotic lesion are not fully understood. It has been widely assumed that plaque morphology is the major determinant of clinical outcome [1, 2].
APA, Harvard, Vancouver, ISO, and other styles
9

Santos, Leonardo Daniel Reis, Omar Pereira de Almeida Neto, Michelle Franco Macedo de Lima, and Nathália Varano. "Left atrial myxoma and transient ischemic attacks: case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.205.

Full text
Abstract:
Context: Cardiac tumors are rare and myxomas are the most prevalent between them. Although histologically benign, they may cause severe effects given their intracardiac location. Unspecific symptoms compromise the diagnosis, leading to complications such as changes in the cerebral vascular dynamics. Case report following the CARE guidelines. Case report: A 62-year-old woman was admitted to a high complexity hospital in Minas Gerais, with history of unstable angina, aphasia, right hemiparesis, dysarthria, claiming precordialgia with strong intensity. Complained hyporexia and weight loss during the last month. Medical history of 7 transient ischemic attacks (TIA) in the last two years. Physical examination with no abnormalities. Chest x-ray and transesophageal echocardiogram showed bilateral neovascularization and 4.9 x 2.9 cm dimension mass in the left atrium. Coronary angiography revealed proximal calcification and atherosclerotic plaque occluding 40% of the flux in the middle third of the anterior descending artery, pointing to the coexistence of coronary disease and left atrial myxoma. The occurrence of a TIA was determined and the prescription of an anticoagulant to avoid future embolic events. A surgical approach was necessary. Biopsy concluded myxoid and hyaline-rich stroma tumor, evident vascular system, star-shaped cells isolated or forming small groups, confirming myxoma diagnosis. After a ten-day hospitalization, the patient was clinically stable, and was discharged after health education. Conclusion: Cardiac tumors such as myxomas lead to important cerebral vascular consequences, so that the clinical investigation is essential to the differential diagnosis between a stroke and the TIA, to provide adequate treatment and disease prevention.
APA, Harvard, Vancouver, ISO, and other styles
10

Киреева, Виктория, Viktoriya Kireeva, Ю. Усольцев, Yu Usolcev, Ж. Капустенская, Zh Kapustenskaya, Е. Кожевникова, et al. "Intermediate results 2016 of a search study of translational diagnostic methods Mitochondrial dysfunction in patients with chronic myocardial ischemia and/or head Brain." In Topical issues of translational medicine: a collection of articles dedicated to the 5th anniversary of the day The creation of a department for biomedical research and technology of the Irkutsk Scientific Center Siberian Branch of RAS. Москва: INFRA-M Academic Publishing LLC., 2017. http://dx.doi.org/10.12737/conferencearticle_58be81ec94893.

Full text
Abstract:
Purpose of the study. To rate prognostic properties of changes in mitochondrial DNA concentration in the blood plasma of patients with chronic cerebral ischemia and ischemic heart disease in relation to the disease and the effectiveness of the therapy. Materials and methods. The study involved patients suffering from coronary heart disease (CHD) and chronic cerebral ischemia (CCI) with stable and unstable atherosclerotic plaques, who have signed informed consent to the data processing within the framework of scientific research. The patients were admitted to the hospital for examination and treatment of CHD and CCI in Cardiology and Neurology Unit of the Hospital of ISC SB RAS. The subjects underwent laboratory and instrumental examination and analysis of the level of free circulating serum mitochondrial DNA by real-time PCR (copies/ml). The examination results considered as satisfactory were compared with the mtDNA levels before and after the treatment. Results. The average value of the mtDNA levels before and after the treatment in patients of neurological and cardiological profile were significantly different: 1 093 686 copies/ml vs 418 046 copies/ml, respectively (p = 0.02). Unlike women, men mtDNA levels statistically significantly (p = 0.03) decreased after the treatment. We revealed statistically significant differences in mtDNA level indicators before and after the treatment, depending on the definition of the series (p = 0.0010) for rank test Kruskal – Wallis test. The results of the proposed research will help to identify prognostic factors of destabilization of cell damage and plaques in endothelial dysfunction, atherosclerosis and its complications, to conduct clinical test of the method for predicting and diagnostics of cellular damage in chronic ischemia on a background of atherosclerosis.
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Coronary heart disease Complications Prevention"

1

Xie, Bo, Xiaojiao Cui, Hao Wang, Fuqiang Liu, Fang Qin, Jun Zhang, and Xiaoqing Yi. Prevention of contrast-induced acute kidney injury by probucol combined with hydration in patients with coronary heart disease: a systematic review and meta analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2022. http://dx.doi.org/10.37766/inplasy2022.5.0157.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Wei, Dongmei, Yang Sun, and Hankang Hen. Effects of Baduanjin exercise on cardiac rehabilitation after percutaneous coronary intervention: A protocol for systematic review and meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0080.

Full text
Abstract:
Review question / Objective: Can Baduanjin exercise improve the cardiac rehabilitation of patients with coronary artery disease after percutaneous coronary artery surgery? Condition being studied: Coronary heart disease (CHD), also known as coronary artery disease (CAD), is the single most common cause of death globally, with 7.4 million deaths in 2013, accounting for one-third of all deaths (WHO 2014). PCI has been shown to be effective in reducing mortality in patients with CHD. During follow-up, it has been shown that the benefits of PCI can be offset by the significant risks of coronary spasm, endothelial cell injury, recurrent ischemia, and even restenosis or thrombus. Numerous guidelines endorse the necessity for cardiac rehabilitation (CR), which is recommended for patients with chronic stable angina, acute coronary syndrome and for patients following PCI. Baduanjin have been widely practised in China for centuries, and as they are considered to be low risk interventions, their use for the prevention of cardiovascular disease is now becoming more widespread. The ability of Baduanjin to promote clinically meaningful influences in patients with CHD after PCI, however, still remains unclear.
APA, Harvard, Vancouver, ISO, and other styles
3

Treadwell, Jonathan R., James T. Reston, Benjamin Rouse, Joann Fontanarosa, Neha Patel, and Nikhil K. Mull. Automated-Entry Patient-Generated Health Data for Chronic Conditions: The Evidence on Health Outcomes. Agency for Healthcare Research and Quality (AHRQ), March 2021. http://dx.doi.org/10.23970/ahrqepctb38.

Full text
Abstract:
Background. Automated-entry consumer devices that collect and transmit patient-generated health data (PGHD) are being evaluated as potential tools to aid in the management of chronic diseases. The need exists to evaluate the evidence regarding consumer PGHD technologies, particularly for devices that have not gone through Food and Drug Administration evaluation. Purpose. To summarize the research related to automated-entry consumer health technologies that provide PGHD for the prevention or management of 11 chronic diseases. Methods. The project scope was determined through discussions with Key Informants. We searched MEDLINE and EMBASE (via EMBASE.com), In-Process MEDLINE and PubMed unique content (via PubMed.gov), and the Cochrane Database of Systematic Reviews for systematic reviews or controlled trials. We also searched ClinicalTrials.gov for ongoing studies. We assessed risk of bias and extracted data on health outcomes, surrogate outcomes, usability, sustainability, cost-effectiveness outcomes (quantifying the tradeoffs between health effects and cost), process outcomes, and other characteristics related to PGHD technologies. For isolated effects on health outcomes, we classified the results in one of four categories: (1) likely no effect, (2) unclear, (3) possible positive effect, or (4) likely positive effect. When we categorized the data as “unclear” based solely on health outcomes, we then examined and classified surrogate outcomes for that particular clinical condition. Findings. We identified 114 unique studies that met inclusion criteria. The largest number of studies addressed patients with hypertension (51 studies) and obesity (43 studies). Eighty-four trials used a single PGHD device, 23 used 2 PGHD devices, and the other 7 used 3 or more PGHD devices. Pedometers, blood pressure (BP) monitors, and scales were commonly used in the same studies. Overall, we found a “possible positive effect” of PGHD interventions on health outcomes for coronary artery disease, heart failure, and asthma. For obesity, we rated the health outcomes as unclear, and the surrogate outcomes (body mass index/weight) as likely no effect. For hypertension, we rated the health outcomes as unclear, and the surrogate outcomes (systolic BP/diastolic BP) as possible positive effect. For cardiac arrhythmias or conduction abnormalities we rated the health outcomes as unclear and the surrogate outcome (time to arrhythmia detection) as likely positive effect. The findings were “unclear” regarding PGHD interventions for diabetes prevention, sleep apnea, stroke, Parkinson’s disease, and chronic obstructive pulmonary disease. Most studies did not report harms related to PGHD interventions; the relatively few harms reported were minor and transient, with event rates usually comparable to harms in the control groups. Few studies reported cost-effectiveness analyses, and only for PGHD interventions for hypertension, coronary artery disease, and chronic obstructive pulmonary disease; the findings were variable across different chronic conditions and devices. Patient adherence to PGHD interventions was highly variable across studies, but patient acceptance/satisfaction and usability was generally fair to good. However, device engineers independently evaluated consumer wearable and handheld BP monitors and considered the user experience to be poor, while their assessment of smartphone-based electrocardiogram monitors found the user experience to be good. Student volunteers involved in device usability testing of the Weight Watchers Online app found it well-designed and relatively easy to use. Implications. Multiple randomized controlled trials (RCTs) have evaluated some PGHD technologies (e.g., pedometers, scales, BP monitors), particularly for obesity and hypertension, but health outcomes were generally underreported. We found evidence suggesting a possible positive effect of PGHD interventions on health outcomes for four chronic conditions. Lack of reporting of health outcomes and insufficient statistical power to assess these outcomes were the main reasons for “unclear” ratings. The majority of studies on PGHD technologies still focus on non-health-related outcomes. Future RCTs should focus on measurement of health outcomes. Furthermore, future RCTs should be designed to isolate the effect of the PGHD intervention from other components in a multicomponent intervention.
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography