Academic literature on the topic 'Coronary'

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Journal articles on the topic "Coronary"

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Silva, Marco Antônio Gomes da. "Resistência plaquetária ao clopidrogel em pacientes diabéticos submetidos à intervenção coronariana percutânea: revisão da literatura." Revista Recien - Revista Científica de Enfermagem 9, no. 27 (September 17, 2019): 73. http://dx.doi.org/10.24276/rrecien2358-3088.2019.9.27.73-78.

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A antiagregação plaquetária é peça chave no tratamento dos pacientes submetidos a intervenção coronaria percutânea com implante de stent coronariano. Entretanto, uma parcela destes pacientes não se encontram devidamente antiagregados. O objetivo foi identificar mediante a revisão de literatura, artigos que mostram os mecanismo de resistência plaquetária ao clopidrogel em pacientes diabéticos submetidos à intervenção coronariana. Trata-se de uma pesquisa de revisão de literatura no qual os artigos estavam disponíveis nas bases de dados SCIELO, LILACS e PubMed, publicados entre os anos de 2006 a 2015 com os seguintes descritores: inibidores da agregação plaquetária, intervenção coronária percutânea e doença da artéria coronária. Foram encontradas seis publicações cientificas entre os anos de 2006 a 2015 abordando o tema da pesquisa. Foi possível observar nas publicações um alto índice de resistência plaquetária ao clopidrogel nos pacientes diabéticos em relação com os pacientes não diabéticos.Descritores: Inibidores da Agregação Plaquetária, Intervenção Coronária Percutânea, Doença da Artéria Coronária. Platelet Resistance to Clopidogel in Diabetic Patients Undergoing Percutaneous Coronary Intervention: literature reviewAbstract: Platelet antiaggregation is a key element in the treatment of patients undergoing percutaneous coronary intervention with coronary stent implantation. However, a portion of these patients are not adequately antiaggregated. The objective was to identify through the literature review, articles that show the mechanisms of platelet resistance to clopidrogel in diabetic patients submitted to coronary intervention. This is a review of the literature in which the articles were available in the SCIELO, LILACS and PubMed databases, published between the years 2006 and 2015, with the following descriptors: platelet aggregation inhibitors, coronary intervention percutaneous coronary artery disease. Six scientific publications were found between the years 2006 and 2015, addressing the research theme. It was possible to observe a high index of platelet resistance to clopidrogel in diabetic patients in relation to non-diabetic patients.Descriptors: Platelet Aggregation Inhibitor, Percutaneous Coronary Intervention, Coronary Artery Disease. Resistencia plaquetaria con clopidogrel en pacientes diabéticos sometidos a intervención coronaria percutánea: revisión de la literaturaResumen: Platelet antiagregación es un elemento clave en el tratamiento de los pacientes en curso percutáneo coronario con una coronaria stent implantación. Sin embargo, la parte de estos pacientes no está adecuadamente antiagregada. El objetivo era identificar a través de la revisión, los artículos que muestran los ajustes de la resistencia al azar en el clopidrogel en los pacientes diabéticos sometidos a una intervención coronaria. Esta es una revisión de los casos en los que se incluyeron los artículos en el SCIELO, LILACS y PubMed de las bases de datos, publicados entre los años 2006 y 2015, con los siguientes descriptores: los inhibidores de la intervención de la insulina, la interrupción de la intervención de los pacientes. Se han encontrado seis estadísticas científicas entre los años 2006 y 2015, el tema de la investigación. Es posible observar un alto índice de la resistencia al azar en los pacientes con diabetes en pacientes con diabetes.Descriptores: Platelet Aggregation Inhibitor, Corrección de la Coronaria de Coronaria Arterial, Enfermedad de la Arteria Coronaria.
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Hirachan, Anish. "Primary Percutaneous Coronary Intervention in a Case of Dual Right Coronary Artery Presenting As Acute Coronary Syndrome." Clinical Cardiology and Cardiovascular Interventions 4, no. 12 (June 25, 2021): 01–04. http://dx.doi.org/10.31579/2641-0419/183.

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Dual right coronary artery (RCA) is a rare coronary anomaly. This anomaly is often undetected and may be totally asymptomatic to presenting as acute coronary syndrome. Here, we present a 41 year old male diabetic and smoker presented with acute onset severe chest pain of 30 minutes duration which was managed as acute coronary syndrome .His urgent coronary angiogram revealed single ostial origin of right coronary artery ( RCA) with total occlusion from proximal segment followed by double right coronary arteries with their respective distal branches.
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Barik, Ramachandra, Debasish Das, Satyabrata Guru, and Davuluri Sitaram. "Anomalous Origin of Right Coronary Artery from Left Coronary Sinus." Journal of Cardiovascular Medicine and Surgery 2, no. 2 (2016): 61–63. http://dx.doi.org/10.21088/jcms.2454.7123.2216.5.

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Qin, Xuju, Lin Yang, Weiguo Xiong, Chunpeng Lu, and Xuguang Qin. "Anomalous Right Coronary Originating from the Left main Coronary or the mid of Left Anterior Descending Coronary Artery." Clinical Cardiology and Cardiovascular Interventions 4, no. 2 (February 9, 2021): 01–09. http://dx.doi.org/10.31579/2641-0419/113.

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Coronary artery anomalies (CAAs) are very rare a relatively uncommon, diverse group of congenital disorders of coronary arterial anatomy with a clinical presentations. Though most commonly detected incidentally finding during routine catheter, CT angiograms or at autopsy, these anomalies have generated considerable interest as they constitute the second most common cause of sudden cardiac death in young competitive athletes after hypertrophic cardiomyopathy1. Their prevalence ranges from 0.2% to 1.3% based published series 2-4. The most common coronary artery anomaly is origination of the left circumflex coronary (LCX) artery from the proximal of right coronary artery (RCA) or right sinus of Valsalva. The second is separate origination of the left anterior descending coronary artery (LAD) and LCX artery from the left sinus of Valsalva. Herein, we present five cases that the anomalous RCA arises from the left main coronary artery or the mid of left left anterior descending coronary artery (LAD). These cases are extremely rare. we bring forth them in an attempt to highlight their significance, and make cardiologist to understand what important the anomalies are, and how to diagnosis and treatment these bifurcation lesions of coronary anomalies.
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Nurmamadovna, Ishankulova Nasiba. "Coronary Heart Disease." American Journal of Medical Sciences and Pharmaceutical Research 03, no. 02 (February 28, 2021): 31–36. http://dx.doi.org/10.37547/tajmspr/volume03issue02-04.

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The article covers the etiology, pathogenesis, classification, diagnosis, clinical picture and treatment of coronary heart disease, provides a literature review. Cardiovascular disease (CVD) represents the leading cause of death among women as well as men. The number of deaths due to CVD in women are greater than in men. There are significant gender-related differences concerning CVD.
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Ray, Dr Sandipta. "Post Percutaneous Transluminal Coronary Angioplasty (PTCA) Coronary Aneurysm- A Case Report." Journal of Medical Science and clinical Research 12, no. 04 (April 30, 2024): 63–67. http://dx.doi.org/10.18535/jmscr/v12i04.10.

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Introduction Coronary aneurysm defined angiographically as luminal dilation 50% larger than that of the adjacent reference segment. (1) Drug-eluting stents (DES), which locally elute antiproliferative drugs, can dramatically inhibit neointimal growth. However, several pathological studies have indicated that DES may delay healing after vascular injury, and DES implantation may be theoretically associated with a risk of coronary artery aneurysm formation. Coronary aneurysms have been reported from 3 days to up to 4 years after DES implantation procedures, with varying clinical presentations. The incidence of coronary artery aneurysms after DES implantation is low within the first 9 months, with a reported incidence of 0.2% to 2.3%, a rate similar to that reported after bare-metal stent (BMS) implantation (0.3% to 3.9%) in the DES versus BMS randomized trials.(2) However, the true incidence of coronary aneurysms in an unselected patient population is still largely unknown. It can be congenital, or secondary to vasculitis (Kawasaki disease) or after percutaneous coronary intervention. Drug-eluting stents (DES), which locally elute antiproliferative drugs, can dramatically inhibit neointimal growth has become standard of care for routine coronary angioplasty. However, several pathological studies have indicated that DES may delay endothelial healing after vascular injury, and DES implantation may be theoretically associated with a risk of coronary artery aneurysm formation (3)
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Barna, László, Zsuzsanna Takács-Szabó, and László Kostyál. "Coronariaeredési anomáliák kardio-CT-vizsgálatok során." Orvosi Hetilap 161, no. 47 (November 22, 2020): 1995–99. http://dx.doi.org/10.1556/650.2020.31881.

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Összefoglaló. Bevezetés: Congenitalis coronariaanomáliának tekintik azokat a coronariamorfológiai rendellenességeket, melyek 1%-nál kisebb gyakorisággal fordulnak elő. Többségük nem jár tünettel, olykor azonban okozhatnak mellkasi fájdalmat, eszméletvesztést, és hirtelen halálhoz is vezethetnek. A coronariaanomáliák gyakoriságáról Magyarországon eddig csak invazív koronarográfiás adatok alapján jelent meg közlemény. Célkitűzés: Jelen vizsgálatunkban a coronariák eredési rendellenességeinek gyakoriságát mértük fel intézetünk coronaria-komputertomográfiás angiográfián átesett betegeinél. Módszer: A coronaria-komputertomográfiás vizsgálatra került betegek felvételeinek értékelésekor rögzítettük a coronariaanomália jelenlétét. A vizsgálat indikációja általában mellkasi fájdalom volt. 128 szeletes berendezést használtunk, a vizsgálatok során részben retrospektív, részben prospektív EKG-kapuzást alkalmaztunk. Eredmények: 1751 beteg komputertomográfiás angiográfiás felvételeit elemeztük. A betegek között a férfiak aránya 38,4%, a vizsgálatra kerülők életkorának átlaga pedig 58,07 ± 11,07 év volt. Eredési anomáliát 1,83%-ban találtunk, ezen belül a leggyakoribb volt a körbefutó ág (ramus circumflexus) és az elülső leszálló ág különálló eredése a bal Valsalva-sinusból (1%). A további rendellenességek a következők voltak: a jobb coronaria eredése magasan az aortából (0,34%), ramus circumflexus a jobb sinusból vagy a jobb coronariából (0,34%), jobb coronaria a bal Valsalva-sinusból (0,057%), elülső leszálló ág részben a bal Valsalva-sinusból a circumflexustól külön, részben a jobb coronariából (kettős elülső leszálló ág, 0,057%). Következtetés: Mindössze 0,057%-ban fordult elő potenciálisan tünetet okozó coronariaeredési rendellenesség (a bal sinusból eredő jobb coronaria). A komputertomográfiás angiográfia segítségével a coronariaeredés helye pontosan megállapítható, tisztázható az ér lefutása és ennek során viszonya a környező struktúrákhoz. Orv Hetil. 2020; 161(47): 1995–1999. Summary. Introduction: Congenital coronary artery anomaly is defined as a coronary morphology which occurs in less than 1% of the cases. Usually these anomalies do not result in symptoms but sometimes they can cause chest pain, syncope and sudden death. In Hungary, the prevalence of these abnormalities was published only from data of invasive coronary angiography. Objective: In this study, we evaluated the prevalence of the anomalies of coronary origin in the patients of our institution undergoing coronary computed tomography. Method: While reading the computed tomography angiograms of our patients, we registered the presence of coronary anomalies. In most of the cases, the indication of the coronary computed tomography was chest pain. A scanner with 128 detectors was used, scans were performed partly with prospective, partly with retrospective ECG gating. Results: We assessed 1751 patients. The ratio of males was 38.4%, while the average age of patients 58.07 ± 11.07 years. Anomaly of coronary origin was present in 1.83% of our patients, with the separate origin of left anterior descending and left circumflex artery being the most frequent (1%) among them. Other anomalies were as follows: high take-off of the right coronary artery from the ascending aorta (0.34%), left circumflex arising from the right sinus of Valsalva or from the right coronary (0.34%), right coronary artery from the left sinus of Valsalva (0.057%), left anterior descending arising partly from the left sinus of Valsalva, apart from the left circumflex, partly from the right coronary (dual left anterior descending artery, 0.057%). Conclusion: The prevalence of potentially symptomatic coronary anomalies was only 0.057% in our series (right coronary from the left sinus of Valsalva). The computed tomography angiography can precisely define the origin of the coronary artery, depict its run-off and its relationship to the neighbouring structures. Orv Hetil. 2020; 161(47): 1995–1999.
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PINARCI, Cihat, and Selen BAYRAKTAROĞLU. "Oldukça nadir bir koroner arter anomalisi: Non-koroner sinüsten çıkan sol ana koroner arter." Ege Tıp Dergisi 61, no. 2 (June 13, 2022): 309–11. http://dx.doi.org/10.19161/etd.1127945.

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Although they are rare, left coronary artery anomalies can cause complications with high mortality, including arrhythmia and cardiac arrest. Left main coronary artery originates from the non-coronary sinus abnormality is rarely observed. This abnormality has been defined as a benign pathology in the past, although it is described in the literature to cause morbidity and mortality in some cases. We present very rare case of the left main coronary artery arising from non-coronary sinus detected on CCTA.
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Ajmone, F., M. Mancone, G. Sardella, M. Tocci, E. Bruno, R. Improta, G. Di Pietro, A. Giansante, C. Vizza, and R. Colantonio. "DOUBLE ST–ELEVATION, DOUBLE OCCLUSION?" European Heart Journal Supplements 26, Supplement_2 (April 2024): ii183. http://dx.doi.org/10.1093/eurheartjsupp/suae036.442.

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Abstract Case Presentation A 71–year–old woman was referred to our outpatient clinic for two episodes of chest pain during last two days. Her past medical history was remarkable for arterial hypertension, obesity, diabetes mellitus type 2 treated by oral hypoglycaemic agents complicated by diabetic maculopathy. Diagnostic Work–Up At the presentation, the patient was symptomathic for chest pain, hemodynamically stable. The ECG showed synus rhythm, left–axis deviation, Q wave and ST–elevation from V2 to V5 and in DIII and ST–elevation in DII and aVF (FIGURE 1). Transthoracic echocardiography revealed concentric hypertrophy, mildly reduced LV ejection fraction (EF 45%) with akinesia of intreventricular septum and apex, without severe valvulopathies and no pericardial effusion. Given the clinical data the patient was addressed to urgent coronary angiography that showed LAD occlusion at the end of his proximal tract and right coronary artery occlusion at the beggining of his second tract (FIGURE 2); furthermore omo and etero–coronaric collaterals for right coronary artery area were detected. By using a workhorse guidewire flow was restored in both coronary arteries and PTCA was performed with 3 DES on LAD and other 2 DES on right coronary artery (FIGURE 3). The patient was transferred to our coronaric intensive unit care after the procedure; no complications were noticed during the hospitalization. A week after the patient was discharged in good general health. Conclusion Multiple simultaneous coronary occlusions are reported in literature, yet the accurate incidence and physiopathology of this occurrence is still uncertain. Probably the symphathetic system activation caused by first coronary occlusion could promote an increased basal platelets activation and then the second coronary occlusion. Our case shows that during coronary angiography identifying a culprit lesion may be delicate and cardiologists should be prepared to manage multiple coronary occlusions.
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PANDA, DR SAMIR KUMAR, DR KAMAL LOCHAN BEHERA, DR SIDDHARTHA REDDY, and DR K. JAGADEESH BABU. "Acute Coronary Syndrome With Anomalous Origin of Left Circumflex From Right Coronary Artery." Indian Journal of Applied Research 4, no. 2 (October 1, 2011): 6–8. http://dx.doi.org/10.15373/2249555x/feb2014/106.

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Dissertations / Theses on the topic "Coronary"

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Adjedj, Julien. "Circulation coronaire : Principes et méthodes de mesure invasive du flux coronaire segmentaire en pratique clinique." Thesis, Paris Est, 2017. http://www.theses.fr/2017PESC0006/document.

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La circulation artérielle coronaire est un système complexe dont les méthodes de mesures invasivespermettent une évaluation en pratique clinique.Matériels et méthodes Nous développons, dans deux revues, les principes et méthodes des différentes techniques invasivesde mesure du flux coronaire en pratique clinique. Puis nous étudions l’impact clinique de l’utilisationde la Fractional Flow Reserve (FFR) dans l’évaluation des sténoses coronaires intermédiaires, lesmoyens pharmacologiques pour mesurer la FFR et sa corrélation avec l’évaluation angiographique enfonction des facteurs de risque cardiovasculaires. Enfin, nous décrivons les principes et méthodesd’une technique de mesure du flux coronaire segmentaire permettant d’obtenir la FFR, le flux et lesrésistances absolues avec un microcathéter de perfusion qui, sur un principe de thermodilutionpermet d’évaluer distinctement la macro et la microcirculation coronaire.Résultats Nous recommandons une valeur seuil de FFR de 0,80 pour guider la revascularisation car le nombred’événements cardiovasculaires et la mortalité sont spontanément supérieurs chez les patients avecune FFR <0,80 comparativement à une FFR ≥0,80 (9,4 vs. 4,8%, P=0,06 et 7,5 vs. 3,2%, P=0,06;respectivement). Nous avons étudié différents agents hyperémiants permettant de mesurer la FFR:l’adénosine (100 μg à 200 μg) permettant d’obtenir une hyperémie maximale, et le produit decontraste permettant d’atteindre 65% de cette hyperémie maximale. La mesure de la FFR avec duproduit de contraste permet de meilleures performances diagnostiques que les indices de reposcomparé à la FFR sous adénosine. Nous avons établi que la corrélation entre la FFR et le degré desténose angiographique est faible et inversement proportionnel au nombre de facteurs de risquecardiovasculaires, particulièrement chez les patients diabétiques. Enfin, nous avons décrit dans troisétudes, le principe de thermodilution coronaire et la méthode de mesures du flux coronaire et desrésistances microvasculaires avec un microcathéter de perfusion intracoronaire spécifique. Nousavons montré que cette technique est précise (R=0,98), qu’elle induit une hyperémie maximale etlocale sans agent hyperémiant et quelle est reproductible chez l’homme (R=0,91).Conclusion La compréhension de la circulation coronaire et l’application chez l’homme des techniques demesure du flux coronaire segmentaire sont essentielles tant en pratique clinique courante qu’enrecherche
Coronary circulation is complex and highly regulated while invasive coronary flow measurements techniques allow the assessment of coronary physiology in clinical practice. Material et methods We describe in two reviews the principles and methods of different invasive coronary flowmeasurements techniques in clinical practice. We study the clinical impact of fractional flow reserve(FFR) in intermediate coronary stenosis, the hyperemic agents and dosage to measure FFR and FFRcorrelation with angiographic indices according to risk factors accumulation. Finally, we describe the principle and method of coronary flow and microvascular resistances measurements with a dedicated infusion microcatheter for coronary thermodilution to obtain assessment of macro and microvascular components of coronary circulation. Results We recommend the FFR cut off value of 0.80 to guide revascularization based on our study showing higher myocardial infarction and death rate in patients treated with medical therapy and FFR<0.80compared to those with FFR>0.80, respectively 9.4 versus 4.8%, P=0.06 and 7,5 versus 3,2%, P=0.06. We studied different hyperemic agents and dosages and showed that intracoronary adenosine at 100μg to 200 μg induce maximal hyperemia while contrast medium induce 65% of maximal hyperemia. Therefore, FFR measurements with contrast medium is feasible and has better accuracy than restindices compared to FFR. We establish the weak correlation between FFR and angiographic indicesand weakens correlation as risk factors accumulates, especially in diabetic patients. Finally, we described in three studies the method of absolute coronary flow and microvascular resistancesmeasurements based on thermodilution principle with a dedicated infusion catheter. We showed anaccurate measurement with this technique (R=0.98), which induces maximal hyperemia without theneed of hyperemic agent with reproducible measurements in humans (R=0,91).Conclusion The use of invasive coronary flow measurements to study the coronary circulation is essential inclinical practice and in research
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Lee, Chi-hang, and 李志恆. "Microvascular obstruction following percutaneous coronary interventionfor coronary artery disease." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43278723.

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Lee, Chi-hang. "Microvascular obstruction following percutaneous coronary intervention for coronary artery disease." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43278723.

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Lee, Paul Man-Yiu. "Critical coronary stenosis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/nq23948.pdf.

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梁永雄 and Wing-hung Leung. "Quantitative coronary arteriography." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1991. http://hub.hku.hk/bib/B31981483.

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Warnes, C. A. "Sudden coronary death." Thesis, University of Newcastle Upon Tyne, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379320.

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Jensen, Jens. "On-line vectorcardiography during coronary angioplasty and unstable coronary artery disease /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4357-5/.

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Geluk, Christiane Anneliese. "Coronary risk stratification from PREVEND to the prevention of coronary events /." [S.l. : Groningen : s.n. ; University Library of Groningen] [Host], 2008. http://irs.ub.rug.nl/ppn/305742574.

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Perera, Shyam Divaka. "The coronary collateral circulation in the setting of percutaneous coronary intervention." Thesis, King's College London (University of London), 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.444572.

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Carrillo, Suárez Xavier. "Diagnóstico y pronóstico de la cardiopatía isquémica asociada al consumo de cocaína." Doctoral thesis, Universitat Autònoma de Barcelona, 2017. http://hdl.handle.net/10803/457526.

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Introducción: El consumo recreacional de cocaína ha aumentado en los últimos años en Europa, siendo España uno de los principales países consumidores de cocaína. La cocaína tiene múltiples efectos sobre el sistema cardiovascular, entre ellos ser desencadenante de un Síndrome Coronario Agudo (SCA). Método: Estudio observacional prospectivo, entre 2001 y 2014, en pacientes con SCA menores de 50 años que ingresaban en la unidad coronaria. Se realizó una anamnesis específica del consumo de cocaína y una determinación de los metabolitos de cocaína en orina. Nuestra hipótesis de trabajo fue “El consumo reciente de cocaína asociado a un síndrome coronario agudo (SCA-ACC) tiene un impacto pronóstico deletéreo a corto y largo plazo respecto al SCA no debido a cocaína”. Se definió el SCA-ACC en aquellos pacientes con SCA y determinación positiva de metabolitos de cocaína en orina o consumo reciente de cocaína por anamnesis. Resultados: Se incluyeron 1002 pacientes menores de 50 años con SCA. El 15.1% reconocían haber consumido cocaína alguna vez en su vida (el 41.7% eran exconsumidores, el 33.1% eran consumidores ocasionales y el 25.2% eran consumidores habituales de cocaína). Observamos un incremento en la prevalencia de consumo de cocaína des del 6.6% en 2002 hasta un pico del 21.7% y 20.5% en 2008 y 2009. Obtuvimos una determinación de metabolitos en orina en 864 pacientes (86.2%), siendo positiva en 52 (6%). Presentaban un SCA-ACC 59 pacientes (6.8%). Los pacientes con antecedentes de consumo de cocaína presentaban un mayor consumo de tóxicos además de cocaína como el tabaco, el alcohol y las otras drogas. En los pacientes con SCA-ACC observamos una mayor frecuencia de presentación como SCA con elevación del segmento ST (SCAEST). Los pacientes con SCA-ACC recibieron menos tratamiento con betabloqueantes en la fase aguda (40.7 contra 78.1%, p<0.001) y también al alta (59.6 contra 84.2%, p<0.001). Sin diferencias en los tratamientos de reperfusión realizados a los pacientes con SCAEST, únicamente una menor utilización de stents farmacoactivos (17.6 contra 34.5%, p=0.043). Durante la fase hospitalaria los SCA-ACC presentaron mayores complicaciones hospitalarias como la taquicardia ventricular (16.9 contra 4.7%, p<0.001), shock cardiogénico (6.8 contra 2.2%,p=0.032) y trastorno agudo de la conducción intraventricular (6.8 contra 1.5%,p=0.004) y una tendencia a mayor mortalidad hospitalaria (3.4 contra 1.0,p=0.097). El seguimiento realizado al 92.4% de los pacientes (mediana de 2381 días) observamos una mayor mortalidad en los pacientes con SCA-ACC (12.3 contra 5%,p=0.020) y también mortalidad cardiaca (7 contra 1.2%,p<0.001). El evento combinado de muerte, infarto o revascularización (MACE) también fue superior en SCA-ACC (35.1 contra 18.8%,p=0.003). El análisis multivariado de supervivencia por Coxx ajustado por la clasificación de killip y el tratamiento al alta presentó una HR de 2.126 ([IC 0.926-4.881],p=0.075) para mortalidad global, 4.038 ([IC 1.151-14.168],p=0.029) para mortalidad cardiaca y 2.015 ([IC 1.247-3.255],p=0.004) para MACE. Conclusiones: El tratamiento administrado en los pacientes con SCA-ACC es diferente al SCA-NACC, utilizando una menor proporción de fármacos betabloqueantes, así como de stents liberadores de fármaco en los procedimientos de intervencionismo coronario. Los pacientes con SCA-ACC tienen una peor evolución al seguimiento que los pacientes con SCA-NACC con una mayor incidencia de trombosis del stent, una mayor mortalidad (global y especialmente la de causa cardiaca) y tienen mayores eventos isquémicos, principalmente el infarto de miocardio. En nuestro medio se confirma nuestra hipótesis y los pacientes con síndrome coronario agudo asociado al consumo reciente de cocaína presentan un peor pronostico hospitalario con mayor numero de complicaciones hospitalarias y un peor pronostico a largo plazo con mayor mortalidad y infarto de miocardio al seguimiento.
Background: Recreational cocaine consumption in European countries has increased in recent years, and Spain is one of the main cocaine-using country in Europe. Cocaine has several effects on the cardiovascular system, being a trigger for Acute Coronary Syndrome (ACS). Methods: A prospective observational study was conducted between 2001 and 2014 in patients admitted to our coronary unit younger than 50 years old who suffered from an ACS. A detailed history of cocaine use and a determination of the metabolites of cocaine in urine were performed. Our working hypothesis was "Recent cocaine use associated with an acute coronary syndrome (ACS-ACC) has a deleterious short- and long-term prognostic impact on ACS not due to cocaine." Recent cocaine use associated with ACS (ACS-ACC) was defined as positive determination of cocaine metabolites in urine or admitting recent cocaine consumption prior to admission in the anamnesis in those patients who suffered an ACS. Results: 1002 patients younger than 50 years with ACS were included. 15.1% reported having consumed cocaine at least once in their lifetime (41.7% were former users, 33.1% occasional users and 25.2% current users). We observed an increase in prevalence of cocaine use from 6.6% in 2002 to a peak of 21.7% and 20.5% in 2008 and 2009. Determination of metabolites was obtained in 864 patients (86.2%), being positive in 52 (6%). A total of 59 patients (6.8%) presented a ACS-ACC. Patients with a history of cocaine use had a higher consumption of other substances, such as tobacco, alcohol, and other. Higher frequency of ACS with ST segment elevation was observed in cocaine users. The group of patients with ACS-ACC received less treatment with beta-blockers in the acute phase (40.7 vs 78.1%, p<0.001) and also at discharge (59.6 vs 84.2%, p<0.001). Differences in reperfusion treatments for patients with ACS-ACS were not observed in spite of a lower lower use of drug-eluting stents (17.6 vs 34.5%, p=0.043). During hospitalization, patients with ACS-ACC presented higher complications such as ventricular tachycardia (16.9 vs 4.7%, p<0.001), cardiogenic shock (6.8% vs 2.2%, p=0.032) and acute intraventricular conduction abnormalities (6.8 vs 1.5%,p=0.004) as well as a trend towards a higher hospital mortality (3.4 vs 1.0, p=0.097). Higher mortality in patients with ACS-ACC was observed (12.3% vs 5%, p=0.020) and also cardiac mortality (7% vs. 1.2%, p<0.001). The combined event of death, infarction or revascularization (MACE) was also higher in ACS-ACC (35.1 vs 18.8%, p = 0.003). Coxx survival multivariate analysis adjusted for killip classification and treatment at discharge showed a HR of 2.126 ([IC 0.926-4.881], p = 0.075) for overall mortality, 4,038 ([1,151-14,168], p = 0.029) for cardiac mortality and 2.015 ([1.247-3.255], p=0.004) for MACE. Conclusions: The treatment given in patients with ACS-ACC differs from patients with ACS-NACC, with lower proportion of beta-blocking drugs being used during admission and at discharge as well as a higher implantation of drug-eluting stents in coronary intervention procedures. Patients with ACS-ACC have a worse outcome at follow-up than patients with ACS-NACC with more incidence of stent thrombosis, higher mortality (overall and especially cardiac cause) and higher ischemic events, mainly miocardial infarction. Our hypothesis is confirmed in our setting, and patients with acute coronary syndrome associated with recent cocaine use have worse hospital prognosis with greater number of hospital complications, worse long-term prognosis with higher mortality and myocardial infarction at follow-up.
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Books on the topic "Coronary"

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Sigwart, Ulrich, and George I. Frank, eds. Coronary Stents. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-76924-5.

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Tomanek, Robert J. Coronary Vasculature. Boston, MA: Springer US, 2013. http://dx.doi.org/10.1007/978-1-4614-4887-7.

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Oudkerk, Matthijs, ed. Coronary Radiology. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-06419-1.

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Pijls, Nico H. J., and Bernard De Bruyne. Coronary Pressure. Dordrecht: Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-015-8834-8.

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Pijls, Nico H. J., and Bernard De Bruyne. Coronary Pressure. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-015-9564-3.

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Spaan, Jos A. E., Albert V. G. Bruschke, and Adriana C. Gittenberger-De Groot, eds. Coronary Circulation. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3369-9.

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Kassab, Ghassan S. Coronary Circulation. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-14819-5.

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Mizuno, Kyoichi, and Masamichi Takano, eds. Coronary Angioscopy. Tokyo: Springer Japan, 2015. http://dx.doi.org/10.1007/978-4-431-55546-9.

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Kajiya, Fumihiko, Gerald A. Klassen, Jos A. E. Spaan, and Julien I. E. Hoffman, eds. Coronary Circulation. Tokyo: Springer Japan, 1990. http://dx.doi.org/10.1007/978-4-431-68087-1.

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Oudkerk, Matthijs, and Maximilian F. Reiser, eds. Coronary Radiology. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-32984-8.

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Book chapters on the topic "Coronary"

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Çimen, Serkan, Mathias Unberath, Alejandro Frangi, and Andreas Maier. "CoronARe: A Coronary Artery Reconstruction Challenge." In Lecture Notes in Computer Science, 96–104. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-67564-0_10.

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Lanzer, Peter, Tilman Markert, Axel Frey, and Rolf Weser. "Coronary Atherosclerosis: Acute Coronary Syndromes." In Pan Vascular Medicine, 746–79. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-56225-9_49.

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Gould, K. Lance. "Coronary Atherosclerosis: Chronic Coronary Syndromes." In Pan Vascular Medicine, 779–820. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-56225-9_50.

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Sandstede, Jörn J. W., Kai-Yiu Y. J. A. M. Ho, and Robert R. Edelman. "Coronary Radiology Update — MR Coronary Angiography." In Coronary Radiology, 117–35. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-06419-1_7.

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de Jonge, Gonda J., Peter M. A. van Ooijen, Jean-Louis Sablayrolles, Guido Ligabue, and Felix Zijlstra. "Coronary Anatomy." In Coronary Radiology, 1–24. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-32984-8_1.

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Van Ooijen, Peter M. A., Jean-Louis Sablayrolles, Guido Ligabue, and Felix Zijlstra. "Coronary Anatomy." In Coronary Radiology, 1–23. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-06419-1_1.

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Tomanek, Robert J. "Coronary Anomalies." In Coronary Vasculature, 101–21. Boston, MA: Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-4887-7_6.

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Pijls, Nico H. J., and Bernard De Bruyne. "Introduction." In Coronary Pressure, 1–4. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-015-9564-3_1.

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Pijls, Nico H. J., and Bernard De Bruyne. "Fractional Flow Reserve in Normal Coronary Arteries." In Coronary Pressure, 191–201. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-015-9564-3_10.

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Pijls, Nico H. J., and Bernard De Bruyne. "Fractional Flow Reserve to Distinguish Significant Stenosis: Use at Diagnostic Catherization." In Coronary Pressure, 203–29. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-015-9564-3_11.

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Conference papers on the topic "Coronary"

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Ramee, Stephen R., Christopher J. White, Juan E. Mesa, Ashit Jain, and Tyrone J. Collins. "Percutaneous coronary angioscopy during coronary angioplasty: clinical findings and implications." In Optics, Electro-Optics, and Laser Applications in Science and Engineering, edited by Abraham Katzir. SPIE, 1991. http://dx.doi.org/10.1117/12.43883.

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Corcoran, David S., Robin Young, David Adlam, Alex McConnachie, Kenneth Mangion, David Ripley, David Cairns, et al. "1 Coronary microvascular dysfunction in stable coronary artery disease: the CE-MARC 2 coronary physiology sub-study." In British Cardiovascular Intervention Society, Young Investigator Award Shortlisted Presentations, Royal College of Physicians of London, November 30 2017. BMJ Publishing Group Ltd and British Cardiovascular Society, 2018. http://dx.doi.org/10.1136/heartjnl-2018-bcis.1.

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Saldeen, T., J. Mehta, W. Nichols, and D. Lew. "THROMBOLYSIS BY TISSUE-PLASMNOCEN ACTIVATOR AND A FIBRIN (OCEN) -DEGRADATION PRODUCT, PEPTIDE 6A, IN A CANINE MDDEL OF ELECTRICALLY-INDUCED CORONARY THROMBOSIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643741.

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Intracoronary thrombus resulting in acute myocardial ischemia can be lysed by thrombolytic agents, such as, streptokinase or t-PA. We examined the potential of a recombitant tissue-plasminogen activator (rt-PA)and a fibrin (ogen)-degradation productpentapeptide 6A, Ala-Arg-Pro-Ala-Lys, corresponding to aminoacids 43-47 in the BB-chain of fibrinogen, which causes marked increase in coronary blood flow and stimulates prostacyclin release, in restoring coronary blood flow in dqgs with experimentally-induced thrombus. An occlusive thrombus was created in the circumflex (Cx) coronary artery in 8 dcgs by electricalstimulation of the endothelial surface. The electrically-induced Cx thrombus consisted primarily of platelets and fibrin. After the occlusive thrcmbus was stable without electrical currant, rt-PA (10ug/kg/minute for 30 minutes intravenously)or peptide 6A (5 unoles/minute for 20 minutes intracorcnary) were randomly administered. Infusion of t-PA restored coronar blood flow (peak 22 ±12 ml/minute, mean ±SD) in five of seven animlas. The time to flow restoration was 12.3 ± 9.1 minutes and the reflow persistedfor20.0 ± 10.9 minutes. Peptide 6A administration also restored coronary blood flow (peak 20 ± 4 ml/ minute) in seven of eight animals with occlusive coronary thrombus. Mean time to blood flow restoration (4.3 ±2.9 minutes) wasshorter(P>0.05) than with rt-PA, but thereflow persisted only for the duration of tine infusion (16.3 ± 10.2 minutes).Peptide 6A adninistration was associatedwith a significant (P±0.05) increase in plasma 6-keto-PGF1α indicating stimulation of prostacyclin release. In addition, plasma t-PA concentrations also increased (F>0.01) at the peak effect of peptide 6A indicating releaseof endogenous t-PA as another potentialmechanism of the thrombolytic effects of peptide 6A. This study demonstrates that peptide 6A exerts coronary thrombolytic effectsccmpa rable to those of t-PA in a canine model of coronary thrombosis.
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Manning, Warren J., and Robert Edelman. "Magnetic resonance coronary angiography." In OE/LASE'93: Optics, Electro-Optics, & Laser Applications in Science& Engineering, edited by Abund O. Wist. SPIE, 1993. http://dx.doi.org/10.1117/12.154959.

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Morioka, Craig A., James S. Whiting, Miguel P. Eckstein, and Kokila C. Shah. "Multiframe quantitative coronary arteriography." In Medical Imaging 1996, edited by Murray H. Loew and Kenneth M. Hanson. SPIE, 1996. http://dx.doi.org/10.1117/12.237913.

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Suurmond, Rolf, Onno Wink, James Chen, and John Carroll. "Three-dimensional coronary angiography." In Medical Imaging, edited by Amir A. Amini and Armando Manduca. SPIE, 2005. http://dx.doi.org/10.1117/12.593740.

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Basit, Sabeen, Shoab A. Khan, and M. Usman Akram. "Segmentation of coronary arteries." In 2014 IEEE Symposium on Industrial Electronics & Applications (ISIEA). IEEE, 2014. http://dx.doi.org/10.1109/isiea.2014.8049873.

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Javid, Tariq, Muhammad Faris, Muhammad Danish Mujib, Tayyab Ahmed Ansari, Hina Iftikhar, Tayyaba Khalid, and Wardah Saadat. "Cardiac Coronary Intervention Simulator." In 2021 IEEE 18th International Conference on Smart Communities: Improving Quality of Life Using ICT, IoT and AI (HONET). IEEE, 2021. http://dx.doi.org/10.1109/honet53078.2021.9615446.

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Bishop, M., U. Chawla, and C. Phillips. "Rare Case of Malignant Right Coronary Artery Originating from Right Coronary Cusp." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3428.

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Fu, Yabo, Bang Jun Guo, Yang Lei, Tonghe Wang, Tian Liu, Walter J. Curran, Long Jiang Zhang, and Xiaofeng Yang. "Mask R-CNN based coronary artery segmentation in coronary computed tomography angiography." In Computer-Aided Diagnosis, edited by Horst K. Hahn and Maciej A. Mazurowski. SPIE, 2020. http://dx.doi.org/10.1117/12.2550588.

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Reports on the topic "Coronary"

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Sun, Jing-Chao, and Xuan-Yan Liu. Intravascular imaging or physiology-guided coronary revascularization in patients with multivessel coronary disease. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2024. http://dx.doi.org/10.37766/inplasy2024.2.0092.

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Banning, Adrian P., and Giovanni Luigi De Maria. Use of Intravascular Ultrasound Imaging in Percutaneous Coronary Intervention on Left Main Coronary Artery Disease. Radcliffe Cardiology, November 2017. http://dx.doi.org/10.15420/rc.2017.m004.

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Liu, H., DD Li, and HM Dai. Percutaneous Coronary Intervention with Stents versus Coronary Artery Bypass Grafting in Treating Unprotected Left Main Coronary Artery Diseases:A Systematic Review and Meta-analysis Comprising 35,409 Patients. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2023. http://dx.doi.org/10.37766/inplasy2023.9.0009.

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Chagas, Gabriel, Rafael Chagas, and Amanda Rangel. Effectiveness and Safety of Single Antiplatelet Therapy with P2Y12 Inhibitor Monotherapy versus Dual Antiplatelet Therapy After Percutaneous Coronary Intervention for Acute Coronary Syndrome: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2022. http://dx.doi.org/10.37766/inplasy2022.7.0097.

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Review question / Objective: What are the effects of single antiplatelet therapy with P2Y12 inhibitor monotherapy versus dual antiplatelet therapy after percutaneous coronary intervention for acute coronary syndrome? Condition being studied: Antiplatelet therapy after percutaneous coronary intervention for acute coronary syndrome. Information sources: The databases will be Medical Literature Analysis and Retrieval System Online (MEDLINE), Excerpta Medica Database (Embase), and Cochrane Library. Searches were conducted on July 25, 2022 and will be updated on August 25, 2022. There will be no language or publication period restrictions.
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Lambert, Charles. Application of Near Infrared Spectroscopy, Intravascular Ultrasound and the Coronary Calcium Score to Predict Adverse Coronary Events. Fort Belvoir, VA: Defense Technical Information Center, October 2012. http://dx.doi.org/10.21236/ada611709.

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Lambert, Charles. Application of Near Infrared Spectroscopy, Intravascular Ultrasound and the Coronary Calcium Score to Predict Adverse Coronary Events. Fort Belvoir, VA: Defense Technical Information Center, October 2014. http://dx.doi.org/10.21236/ada612039.

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Lambert, Charles. Application of Near Infrared Spectroscopy, Intravascular Ultrasound and the Coronary Calcium Score to Predict Adverse Coronary Events. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada591065.

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Sun, Jing-Chao, and Xuan-Yan Liu. Comparison of immediate and staged complete revascularization in patients with acute coronary syndrome and multivessel coronary disease. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2023. http://dx.doi.org/10.37766/inplasy2023.8.0112.

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Wei, Dongmei, Yang Sun, and Hankang Hen. Effects of Baduanjin exercise on cardiac rehabilitation after percutaneous coronary intervention: A protocol for systematic review and meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0080.

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Review question / Objective: Can Baduanjin exercise improve the cardiac rehabilitation of patients with coronary artery disease after percutaneous coronary artery surgery? Condition being studied: Coronary heart disease (CHD), also known as coronary artery disease (CAD), is the single most common cause of death globally, with 7.4 million deaths in 2013, accounting for one-third of all deaths (WHO 2014). PCI has been shown to be effective in reducing mortality in patients with CHD. During follow-up, it has been shown that the benefits of PCI can be offset by the significant risks of coronary spasm, endothelial cell injury, recurrent ischemia, and even restenosis or thrombus. Numerous guidelines endorse the necessity for cardiac rehabilitation (CR), which is recommended for patients with chronic stable angina, acute coronary syndrome and for patients following PCI. Baduanjin have been widely practised in China for centuries, and as they are considered to be low risk interventions, their use for the prevention of cardiovascular disease is now becoming more widespread. The ability of Baduanjin to promote clinically meaningful influences in patients with CHD after PCI, however, still remains unclear.
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Hankerson, Maria, and Allen J. Taylor. The Prospective Army Coronary Calcium (PAAC) Study. Fort Belvoir, VA: Defense Technical Information Center, September 2004. http://dx.doi.org/10.21236/ada430334.

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