Academic literature on the topic 'Cornée – Innervation'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Cornée – Innervation.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Dissertations / Theses on the topic "Cornée – Innervation"
Bouheraoua, Nacim. "Nouvelles analyses transgéniques de l'innervation cornéenne." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066157.
Full textThe cornea is the most densely innervated tissue in the entire body. Corneal innervation plays a role in regulating the secretion of lacrimal film and exerts a direct trophic role on the corneal epithelium. Corneal axons express different types of sensory receptors ranging between mechano-, thermo-, and polymodal nociceptors. We identified transgenic mouse lines to characterize these different axonal populations. Corneal innervation begins at E12.5 in mice and is regulated by a range of axon guidance cues such as Slits and Semaphorins, which respond to their receptors Robo and Plexin/Neuropillin respectively. We studied the role of these two families in the development of corneal innervation. The Slits and Robos mutants show a reduction in the number and size of the corneal epithelial nerves endings. In adult, Robos mutants exhibit early degeneration of the epithelial nerves endings. Plexin-A4 and Neuropilin-1 mutants, on the other hand, show an increase in the number of divisions of the corneal stromal nerve trunks. In adult, Plexin-A4 mutants regain a classical organization of innervation whereas Neuropilin-1 mutants retain the disorganization of corneal innervation. Following a lesion, corneal innervation is able to regenerate, however the axons never regain their initial morphology or complexity. Due to the increased corneal innervation observed in the Neuropilin-1 mutants, we wondered whether the regeneration of innervation after scrapping lesions of the corneal epithelium could be enhanced in Neuropilin-1 loss of function. Our preliminary results support an increase in corneal innervation regeneration in Neuropilin-1 mutants
Bizzarri, Elena. "Study of development and regeneration of corneal innervation in transgenic mice." Electronic Thesis or Diss., Sorbonne université, 2024. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2024SORUS175.pdf.
Full textThe cornea, a transparent and avascular structure located in the anterior segment of the eye, is the most innervated tissue in the human body. It mainly receives sensory inputs from the ophthalmic branch of the trigeminal nerve. Corneal axons distribute from the deepest layer (stroma) to the superficial layer (epithelium), and they exhibit a distinct spiral-like organization. Moreover, corneal nerves are essential in maintaining tissue homeostasis by interacting with epithelial cells releasing neuropeptides.Although standard immunostaining techniques have previously provided insights into corneal nerve patterning, the dynamic organization of corneal axons over time and their response to corneal injuries in live mice is still elusive. Here, we take advantage of CGRP:GFP mouse transgenic line (Bouheraoua et al., 2019), in which the corneal nociceptive C-fibers are labeled, and perform longitudinal live imaging on corneal nerves using 2-Photon (2P) and confocal spinning disk microscopy. By tracking the same area of the cornea over weeks to months, we found that single axons are highly dynamic. They become more centrally organized and exhibit higher branching complexity from the postnatal period (P25) to adulthood. Moreover, we were able to track the corneal nerves in mice from the third postnatal week until aging. We observed that the deep stromal nerves remain constant over time, while the most superficial nerves are remodeled, suggesting a highly dynamic behavior of corneal nerves in space and time.In case of lesion to the corneal epithelium, corneal nerves regenerate already 24 hours post-lesion, followed by subsequent degeneration after 3-4 days. Approximately 6 days post-lesion, axons regenerate from the underlying stromal nerve gradually returning to their initial distribution. Furthermore, we developed a 2P laser ablation protocol to perform axotomy in the stromal nerves and investigate the cross-talk between neuronal and immune cells in the cornea. We were able to follow the dynamics of the interactions between axons and immune cells in Cx3cr1CreER;RosaTomCGRP:GFP mice. After axotomy, immune cells specifically interacted with the corneal nerves, remaining in contact in the following days. In summary, our findings provide new insights into the plasticity of corneal axons and their regenerative potential, suggesting the importance of immune cells in case of lesion. Future studies are necessary to better understand the fundamental mechanism in pathological conditions
Marlier, Lionel. "Plasticité de l'innervation sérotonergique de la corne dorsale de la moe͏̈lle épinière du rat : approche morpho-fonctionnelle." Montpellier 2, 1990. http://www.theses.fr/1990MON20149.
Full textMeyer, Jenna. "Eye-solating corneal innervation profiles to examine epithelial wound healing in a model of type II diabetes." Thesis, 2016. https://hdl.handle.net/2144/19491.
Full textBooks on the topic "Cornée – Innervation"
Burnstock, Geoffrey, and Adam M. Sillito. Nervous Control of the Eye. Taylor & Francis Group, 2003.
Find full textBurnstock, Geoffrey, and Adam M. Sillito. Nervous Control of the Eye. Taylor & Francis Group, 2000.
Find full textBook chapters on the topic "Cornée – Innervation"
Sugimoto, Tomosada, Satoshi Wakisaka, Motohide Takemura, and Masaharu Aoki. "Cell Size and Nissl Pattern Analyses of Primary Afferent Neurons Innervating the Molar Tooth Pulp and Cornea of the Rat." In Processing of Sensory Information in the Superficial Dorsal Horn of the Spinal Cord, 95–98. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-0825-6_11.
Full textNasir, Serdar, and Alaz Cirak. "Reanimation of Mouth Corner with Free Gracilis Muscle Flap." In Facial Nerve Palsy - A Practitioner’s Guide [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.105909.
Full textPanksepp, Jaak. "Emotional Foundations of Creativity." In Secrets of Creativity, 203–19. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190462321.003.0011.
Full textRufai, Sohaib R. "Solutions." In MCQs for FRCOphth Part 1, 18–44. Oxford University PressOxford, 2022. http://dx.doi.org/10.1093/oso/9780192843715.003.0006.
Full textRufai, Sohaib R. "Questions." In MCQs for FRCOphth Part 1, C1—C1P453. Oxford University PressOxford, 2022. http://dx.doi.org/10.1093/oso/9780192843715.003.0001.
Full textConference papers on the topic "Cornée – Innervation"
Masters, Barry R., and Andreas A. Thaer. "Real-time confocal microscopy of corneal innervation in the in-vivo human cornea." In OE/LASE '94, edited by Jean-Marie A. Parel and Qiushi Ren. SPIE, 1994. http://dx.doi.org/10.1117/12.178548.
Full text