Journal articles on the topic 'Cooperative Research Centres'

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1

Tegart, Greg. "The Cooperative Research Centres Programme." Industry and Higher Education 10, no. 3 (June 1996): 160–69. http://dx.doi.org/10.1177/095042229601000304.

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The Cooperative Research Centres programme was initiated in Australia in 1990 to strengthen the linkages between producers and users of research and thus ensure that research results were commercialized where appropriate. In this article, the author discusses the development of centres of expertise in Australian universities against the background of paradigm shifts in innovation, competitiveness and university-government-industry relationships. The Cooperative Research Centres programme represents the most ambitious of the various developments in recent years and he describes the selection, organization and linkages of these Centres. He analyses their impact on universities and on the research culture in Australia. Significant changes are occurring in the attitudes of researchers and traditional systems will need to be adapted to accommodate these changes. The Centres also offer opportunities for a new approach to international cooperation.
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Tornatzky, Louis, Kay Lovelace, Denis O. Gray, S. George Walters, and Eliezer Geisler. "Promoting the Success of US Industry/University Research Centres." Industry and Higher Education 13, no. 2 (April 1999): 101–11. http://dx.doi.org/10.1177/095042229901300202.

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The industry/university (I/U) research centre, once a novelty on university campuses, has become the dominant vehicle for industry's funding of academic research in the USA. While the authors' recent volume, ‘Managing the Industry/University Cooperative Research Center’, documents a variety of skills and competencies needed to build and sustain these boundary-spanning organizations, none plays a more important role in centre success than leadership. Drawing on the literature on leadership and over fifteen years of experience with and research on the National Science Foundation's Industry/University Cooperative Research Centers programme, the authors define and illustrate leadership in the context of an I/U research centre. Leadership in a cooperative research centre often involves helping constituencies to deal with adaptive challenges, situations which require learning both to define the problem and to develop and implement a solution. Since these situations usually involve constituencies with conflicting values and priorities, they are typically best resolved by a participatory leadership style. Critical leadership challenges observed in cooperative research centres are discussed, including: exercising intrapreneurship, creating a compelling technical vision, spanning organizational boundaries, creating cooperative research teams, managing a changing centre and knowing oneself.
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Craig, S. Bartholomew, Clara E. Hess, Jennifer Lindberg McGinnis, and Denis O. Gray. "Leadership in University-Based Cooperative Research Centres." Industry and Higher Education 23, no. 5 (October 2009): 367–77. http://dx.doi.org/10.5367/000000009789711864.

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In spite of the importance often attached to the role played by leadership in university-based cooperative research centres, we know very little about what ‘leadership’ means in this specific context. The research reported here used a qualitative approach to identify fifteen dimensions of leadership performance for directors of university-based cooperative research centres, which might serve as the basis of a future quantitative leadership performance measure. Nineteen university faculty members working in research centres were interviewed, and their responses were content-analysed to identify both facilitators and inhibitors of centre directors' performance. Facilitative performance dimensions included: technical expertise, ambition/work ethic, broad thinking, embracing ambiguity, balancing competing stakeholders, leveraging social capital, obtaining resources, navigating bureaucracy, granting autonomy, interpersonal skill, team building and task adaptability. Inhibiting performance dimensions included: abrasiveness, disorganization and conflict avoidance. The results are discussed in terms of the commonalities and particularities they reveal about cooperative centre leadership relative to leadership performance in other settings.
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Liyanage, Shantha, and Helen Mitchell. "Organizational management in australian cooperative research centres." Technology Analysis & Strategic Management 5, no. 1 (January 1993): 3–14. http://dx.doi.org/10.1080/09537329308524113.

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5

Ban, Elizabeth. "Australian cooperative research centres get thumbs up." Nature Medicine 1, no. 10 (October 1995): 988. http://dx.doi.org/10.1038/nm1095-988a.

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6

Slatyer, Ralph O. "Cooperative research centres: The concept and its implementation." Higher Education 28, no. 1 (July 1994): 147–58. http://dx.doi.org/10.1007/bf01383579.

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7

Noble, David, Michael B. Charles, Robyn Keast, and Robbert Kivits. "Desperately seeking innovation nirvana: Australia’s cooperative research centres." Policy Design and Practice 2, no. 1 (January 2, 2019): 15–34. http://dx.doi.org/10.1080/25741292.2018.1537641.

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8

Turpin, Tim, and Sam Garrett Jones. "Reward, risk and response in Australian cooperative research centres." International Journal of Technology Transfer and Commercialisation 9, no. 1/2 (2010): 77. http://dx.doi.org/10.1504/ijttc.2010.029426.

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9

Betz, Frederick. "Industry/University Centres in the USA." Industry and Higher Education 10, no. 6 (December 1996): 349–54. http://dx.doi.org/10.1177/095042229601000606.

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For two decades, the National Science Foundation (NSF) has had two programmes to sponsor industry/university centres: the Industry/University Cooperative Research (IUCRC) Program and the Engineering Research Centers (ERC) Program. To date, over 70 IUCRC centres have been started by NSF, and over 25 ERC centres have been started. NSF also has a programme to encourage industry/university partnerships on individual projects. From these and other programmes, many lessons have been learned for encouraging productive industry/university/government research partnerships. This article generalizes lessons about appropriate partnerships.
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10

Turpin, Tim, Sam Garrett-Jones, and Richard Woolley. "Cross-sector research collaboration in Australia: the Cooperative Research Centres Program at the crossroads." Science and Public Policy 38, no. 2 (March 1, 2011): 87–98. http://dx.doi.org/10.3152/030234211x12924093660354.

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11

Novak, Metka, and Majda Končar. "Role of gender and age in the cooperation between parents of people with intellectual disabilities and professional staff in care centres." Journal of Health and Rehabilitation Sciences 1, no. 1 (December 25, 2022): 1–14. http://dx.doi.org/10.33700/jhrs.1.1.39.

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Introduction: understanding factors that influence the cooperative relationship between parents of people with intellectual disabilities and professional staff comes from understanding how parents and staff function and, on this basis, from understanding their abilities and skills reflected in their interactions and cooperation. This paper presents some results of a broader study which examined: The aim or research question is how the level of the cooperative relationship between the parents of persons with moderate, severe and profound learning disabilities and the professional staff of Training, Occupation and Care Centres in Slovenia is correlated to the age and gender of parents, and the age and gender of staff. In addition, the study focused on investigating how the gender and age of parents and staff correlates with their inclusion in support groups. Methods: the sample comprised 296 randomly selected parents and 298 randomly selected professional staff. The statistical method of two-way analysis of variance was applied to establish the differences in the level of the cooperative relationship given the gender and the age of the parents and staff. Results: the results confirmed differences relative to the age of the male staff, namely, that with their age the degree of co-operation relationship with parents increases and that fathers are statistically significantly less involved in support groups than mothers. Conclusions: we draw attention to certain concepts associated with a successful cooperative relationship, helping to better understand this relationship and seek new possibilities for more effective cooperation between the parents of PID placed in centres and the staff employed at these centres in Slovenia.
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12

Gray, Denis, Eric Sundstrom, Louis G. Tornatzky, and Lindsey McGowen. "When Triple Helix Unravels." Industry and Higher Education 25, no. 5 (October 2011): 333–45. http://dx.doi.org/10.5367/ihe.2011.0057.

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Cooperative research centres (CRCs) increasingly foster Triple Helix (industry–university–government) collaboration and represent significant vehicles for cooperation across sectors, the promotion of knowledge and technology transfer and ultimately the acceleration of innovation. A growing social science literature on CRCs focuses on their management and best practices, mainly through success stories and rarely by describing and analysing CRC failures. The literature on CRCs can benefit by learning from failures, as has been seen in other areas of social science. Here the authors present four mini-cases of CRC failures – centres that were successfully launched but later declined and closed – and, in contrast, one mini-case of a success story. The analysis identifies: (a) likely contributing factors in the failures, mainly environmental influences and mismanagement of centre transitions; (b) themes in the failures, notably a tendency for problems in one area to magnify the impact of problems in other areas; and (c) learning points for CRCs concerning leadership and succession. The implications for Triple Helix organizations are discussed.
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Steenhuis, Harm-Jan, and Denis O. Gray. "Cooperative research and technology dynamics: the role of research strategy development in NSF Science and Technology Centres." International Journal of Technology Transfer and Commercialisation 5, no. 1/2 (2006): 56. http://dx.doi.org/10.1504/ijttc.2006.008653.

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14

Thomas, P. "Cooperative Research Centres as effective institutions for contemporary models for achieving innovation in primary industry." Animal Production Science 50, no. 6 (2010): 424. http://dx.doi.org/10.1071/an10004.

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The creation of a formal organisational structure that brings together the specific needs of particular industries, with the expertise and research capacity available through recognised research providers, has an underlying and undeniable logic. Cooperative Research Centres (CRCs) provide this formal structure and are generally strongly focussed on carrying out applied outcome-driven research to improve productivity through innovation. Despite this strong commercial focus and record of scientific-output CRCs, there is general recognition that adoption of research from CRCs can be improved. The present paper focuses on primary industry CRCs and discusses the applicability of contemporary innovation concepts, which have evolved through the process of industrialisation and socialisation of science, and their application for improving innovation within primary industry CRCs. Specifically considered are 4th and 5th generation innovation concepts that promote ideas within ‘Open Innovation’ and ‘Knowledge Creation’ as a means of improving innovation within the primary industry CRCs organisational structure.
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Federico, S., and C. Bellecci. "The 11−12 December 2003 storm in Southern Italy." Advances in Geosciences 7 (January 23, 2006): 37–44. http://dx.doi.org/10.5194/adgeo-7-37-2006.

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Abstract. We review an intense and heavy impact storm that occurred over Calabria, southern Italy, during the 11 and 12 December 2003. The event is traced back, at synoptic and planetary scales, up to 5 December 2003 by National Centre for Environmental Prediction/National Centre for Atmospheric Research (NCEP/NCAR) reanalysis fields and backtrajectories. The role of tropical storm Odette is clearly shown as well as that of the Azores high. Even if non negligible water vapour sources are expected from the Mediterranean sea, unusually large precipitable water was present over the Atlantic mid-latitudes. It is shown that tropical storm Odette determined large evaporation from Atlantic Tropics and the cooperative action of synoptic scale and planetary scale pressure centres focused this humidity into a plume and conveyed it into the Mediterranean area.
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16

Farquhar, Graham. "Ralph Owen Slatyer 1929–2012." Historical Records of Australian Science 31, no. 1 (2020): 54. http://dx.doi.org/10.1071/hr19009.

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Ralph Slatyer (16 April 1929–26 July 2012) had a distinguished career in the Commonwealth Scientific and Industrial Research Organisation and the Australian National University, in plant-water relations and plant succession, leading the development of physiological plant ecology. He was the founding Professor of Environmental Biology at the Research School of Biological Sciences, at the Australian National University and then Director of the Research School of Biological Sciences, 1984–9. He was Australian Ambassador to United Nations Educational and Scientific Cultural Organisation (1978–81), and as Australia’s first Chief Scientist (1989–92), he set up the Cooperative Research Centres.
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17

Hobbs, David A., Jo K. Close, Andrew R. Downing, Karen J. Reynolds, and Lloyd T. Walker. "Developing a national research and development centre in assistive technologies for independent living." Australian Health Review 33, no. 1 (2009): 152. http://dx.doi.org/10.1071/ah090152.

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Assistive technology (AT) plays a pivotal role in the lives of people who require assistance with one or more aspects of daily living. Ranging from simple devices such as an augmented fork to complex devices like a power wheelchair with integrated environmental control, AT is a broad term to describe a range of products and services that provide assistance. Historically used in the ?disability sector?, in recent years AT devices have merged into the ageing sector as more Australians develop an impairment through ?age-related disability?, creating a larger market for equipment that provides independence or restores lost/reduced functionality. Despite the national focus on ageing, Australia lacks a nationally coordinated and cohesive AT sector ? most AT equipment and devices are imported and the sector struggles for local research, development, and commercialisation funding. In an attempt to address this issue, a network of rehabilitation engineering and AT centres, universities, and industry players formed a collaboration to submit a Cooperative Research Centre (CRC) proposal to drive Australian AT products and services. The main focus was on developing Australian capacity within the sector and creating innovative products that met Australian needs, leading to import replacement. A secondary focus was on providing a national education program to provide ongoing AT training and development across multiple disciplines associated with both disability and ageing.
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18

Howgrave-Graham, Alan R. "The Composition and Productivity of Australian Cooperative Research Centres, with Emphasis on their Participation in Biotechnology, Regional and Sustainable Development." International Journal of Technology, Knowledge, and Society 6, no. 3 (2010): 67–82. http://dx.doi.org/10.18848/1832-3669/cgp/v06i03/56110.

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19

Lupión-Cobos, Teresa, Jesús Girón-Gambero, and Cristina García-Ruiz*. "Building STEM Inquiry-Based Teaching Proposal Through Collaborations Between Schools and Research Centres: Students’ and Teachers’ Perceptions." European Journal of Educational Research 11, no. 2 (April 15, 2022): 899–915. http://dx.doi.org/10.12973/eu-jer.11.2.899.

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<p style="text-align: justify;">This study presents an inquiry-based teaching approach using a rich methodology involving STEM (science-technology-engineering and mathematics) projects, developed using a cooperative way to work between schools and research centres. We describe the teaching pattern scenario with students, teachers, and scientists. We also illustrate the learning process, conducted through two inquiry-based problems in Biochemistry, the mutagenesis process and the transgenesis effects caused by inoculation of bacteria. The teaching sequence, as well as the scientific knowledge and students’ competencies involved, are shown. We then analyse the students' and teachers' perceptions in this scenario regarding the development of students' STEM learning through their inquiry skills promoted and concerning predictors to vocational careers involved (students’ identities as potential scientists, scientific attitudes, social implications towards science or students´ agency). Finally, we add some conclusions and contributions to teaching STEM education, related to factors of the design teaching scenario that bring connections with the interests and motivations of students, such as the relevance of the projects to evoke understanding of processes or causal relationships of content or the teacher's professionalisation supported by a proper allocation between scientists and teachers.</p>
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20

Bjørkelo, Anders, and Mustafa A. Ali. "A Sudanese Merchant's Career Based on His Papers: A Research Project." History in Africa 17 (January 1990): 31–40. http://dx.doi.org/10.2307/3171804.

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The number of Arabic documents and manuscripts of historical significance found in the Sudan is constantly growing. The national repository for such material is the National Records Office (NRO) in Khartoum, but a substantial collection of photographed, photocopied, and microfilmed documents has also been built up at the Department of History, University of Bergen, Norway. Most of this material has been brought together as a result of fieldwork in various parts of the Sudan in connection with historical research. However, at the end of the 1970s the NRO launched a campaign to collect private documents in the rural areas, with good results. Another step in the same direction was taken in 1986, when a four years' cooperative project between the Department of History, University of Bergen, Norway, and the NRO in Khartoum, was started. Organized joint field expeditions were planned and carried out from 1987 onwards for the purpose of locating and photographing private documents. This project is financed by the Norwegian Aid Agency (NORAD) and the University of Bergen, and is part of a larger program of cooperation with the University of Khartoum. Bjørkelo is the project leader on the Bergen side and Dr. Ali S. Karrar is the local coordinator in the NRO. The 1987 expedition went to al-Matamma, al-Dāmar, Berber, Ghubush, and Kadabās in the north and photographed 196 documents. The following year various religious centres of the Gezira were visited and another 96 documents were photographed. Research on these acquisitions is planned or in progress.
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Spedding, Trish. "Stories of Supervision." Education Sciences 10, no. 4 (March 31, 2020): 93. http://dx.doi.org/10.3390/educsci10040093.

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This article centres upon experiences of supervising practitioner-researchers engaged in the first year of a Customised Master of Philosophy (MPhil) programme of study. This pathway resides within a larger collaboration between the University of Sunderland’s Centre for Excellence in Teacher Training (SUNCETT) and the Education and Training Foundation (ETF) delivering a National Practitioner Research Programme (PRP) in England. It takes as its starting point how non-traditional research students from the further adult and vocational education (FAVE) sector experience entry into the programme and their subsequent development of scholarship and research skills as they pursue their studies at research degree level in higher education (HE). Using six guiding principles underpinning the PRP as a framework for analysis, illustrative stories of the experiences of supervisors and research students provide insights into ways in which supervision is enacted. Some key characteristics of supervision practice are described. These often bring to light differences between supervision on the Customised MPhil with that of conventional MPhil programmes. The most striking finding supports how the development of collaborative and cooperative practice helps to shift the customary dynamic of research degree study away from isolation towards a shared experience as members of an inclusive and active research community.
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Garnett, Stephen T., and Jennifer Haydon. "Mapping Research Capacity in North-Western Tropical Australia." Journal of Information & Knowledge Management 04, no. 03 (September 2005): 141–56. http://dx.doi.org/10.1142/s0219649205001122.

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Research capacity in two jurisdictions in tropical northwestern Australia was mapped to a searchable website. The website provides ready access to all research organisations in the region with the underlying database providing a baseline against which developments in research and research networks can be measured. Of 202 research entities entered into the database, 38 were businesses, 12 civil society organisations, five cooperative research centres, 10 government research institutes, 64 government agencies within three jurisdictions and 70 university research groups within seven universities. The data were analysed by sector to describe the size and linkages between organisations, areas of research strength and socioeconomic objectives of research. Most enterprises undertaking research in tropical Western Australia and the Northern Territory are small with the majority having fewer than 10 research staff. The primary area of expertise for research entities in tropical Western Australia and the Northern Territory is agricultural and environmental research, which is also the area where there is greatest breadth of capacity. Similarly, the socioeconomic objective of most research entities is in fields related to environmental management and social development with the breadth of capacity greatest in environmental policy frameworks. There were substantial differences between the skills and direction of research in government and the universities and those in business.
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23

Entwistle, K. W., L. J. Cummins, M. A. Hillard, J. E. Kinder, T. O'Shea, L. R. Piper, J. Thimonier, and J. F. Wilkins. "Bernard Michael Bindon — reproductive physiologist, animal scientist, research leader." Australian Journal of Experimental Agriculture 46, no. 2 (2006): i. http://dx.doi.org/10.1071/ea05222.

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This paper is a foreword to a series of papers commissioned on ‘the impact of science on the beef industry’, where the Beef CRC-related collaborative scientific work of Professor Bernard Michael Bindon will be reviewed. These papers will be presented in March 2006, as part of a ‘festschrift’ to recognise his wider contributions to the Australian livestock industries for over 40 years. Bindon’s career involved basic and applied research in many areas of reproductive physiology, genetics, immunology, nutrition, meat science and more recently genomics, in both sheep and cattle. Together with his collaborators, he made large contributions to animal science by improving the knowledge of mechanisms regulating reproductive functions and in elucidating the physiology and genetics of high fecundity livestock. His collaborative studies with many colleagues of the reproductive biology and genetics of the Booroola Merino were amongst the most extensive ever conducted on domestic livestock. He was instrumental in the development of immunological techniques to control ovulation rate and in examining the application of these and other techniques to increase beef cattle reproductive output. This paper tracks his investigations and achievements both within Australia and internationally. In the later stages of his career he was the major influence in attracting a large investment in Cooperative Research Centres for the Australian cattle industry, in which he directed a multi-disciplinary approach to investigate, develop and disseminate science and technology to improve commercial cattle productivity.
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Paulino, Isabel, Lluís Prats, and Antoni Domènech. "Breaking Brands: New Boundaries in Rural Destinations." Sustainability 13, no. 17 (September 3, 2021): 9921. http://dx.doi.org/10.3390/su13179921.

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Tourism destinations are generally delimited and branded based on administrative boundaries, which act as artificial barriers that may reduce the competitiveness of the tourism sector. Increasingly, literature is taking a demand perspective (i.e., tourist spatial behaviour) when identifying and promoting destinations. This perspective can help to promote destinations more efficiently, particularly in rural areas, where most tourism flows depend on private vehicle and which do not take into account administrative boundaries. These flows are therefore highly conditioned by the geography of the area, hosting capacity and the cumulative effect of attractions. This research centres on brand creation from a tourist perspective, particularly how tourists consume a destination. Els Ports (Spain), a rural mountain area divided into multiple administrative divisions, each marketing its own brand, is taken as a case study. Recently, destination managers have seen the opportunity for regional cooperation and taken steps to cross traditional boundaries to market the area better. This study uses GIS techniques to compare tourist travel patterns with brand boundaries and new cooperative initiatives. The findings provide material for discussion on the branding strategy of Els Ports and the need to rebrand rural tourism destinations into functional tourism areas.
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Duckett, Jane. "International Influences on Policymaking in China: Network Authoritarianism from Jiang Zemin to Hu Jintao." China Quarterly 237 (November 27, 2018): 15–37. http://dx.doi.org/10.1017/s0305741018001212.

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AbstractPrevious research has credited China's top leaders, Hu Jintao and Wen Jiabao, with the social policies of their decade in power, arguing that they promoted these policies either for factional reasons or to achieve rational, problem-solving goals. But such arguments ignore the dominant “fragmented authoritarian” model of policymaking in China that centres on bargaining among bureaucratic agencies. This article asks whether top leadership factions, rational problem solving, or “fragmented authoritarianism” can explain the adoption of one of the Hu and Wen administration's flagship policies, New Rural Cooperative Medical Schemes. Based on a careful tracing of this policy's evolution, it finds little evidence for these explanations, and instead uncovers the role played by international events and organizations, and ideas they introduced or sustained within policy networks. The article highlights some of the effects that China's international engagement has had on policymaking and the need to go beyond explanations of the policy process that focus solely on domestic actors. It proposes a new model of policymaking, “network authoritarianism,” that centres on policy networks spanning the domestic–international, state–non-state, and central–local divides, and which takes account of the influence of ideas circulating within these networks.
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Newton, Peter W., and Briony C. Rogers. "Transforming Built Environments: Towards Carbon Neutral and Blue-Green Cities." Sustainability 12, no. 11 (June 10, 2020): 4745. http://dx.doi.org/10.3390/su12114745.

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In the 21st century, the creation of built environments that are carbon neutral and water sensitive is critical for addressing sustainable urban development challenges. Both require transformative change: Decarbonisation to mitigate greenhouse gas emissions and incorporation of green-blue water sensitive solutions to adapt to climate change impacts. Transition pathways in both arenas involve combinations of new technology, innovative urban design, enabling policies and regulations, new processes for planning and managing urban development, and demand-side changes in consumer attitudes and practices for urban living related to energy and water use. In this paper, we present new knowledge, concepts and frameworks developed for application in Australia, as well as internationally, through research by the national Cooperative Research Centres for Low Carbon Living (CRCLCL) and Water Sensitive Cities (CRCWSC) between 2012 and 2020. These findings and outputs illustrate common features of the research strategies and initiatives that were central to the activities of the CRCs, and highlight promising directions for collaborative interdisciplinary and transdisciplinary research that drives urban sustainability transformations towards carbon neutral and blue-green cities.
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Howell, Lachlan G., and John C. Rodger. "An examination of funding for terrestrial vertebrate fauna research from Australian federal government sources." Pacific Conservation Biology 24, no. 2 (2018): 142. http://dx.doi.org/10.1071/pc17037.

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Funding for research towards more effective conservation of Australian fauna is widely believed to be low. Publically available data were examined to determine the spread of wildlife projects supported for the period 2005–15 by Federal Government agencies responsible for research and/or environmental management funding and funding aimed at delivering innovation across relevant sectors. A word search method was used and projects categorised according to their relevance to conservation goals. Of the AU$7.2 billion invested by the Australian Research Council, 0.9% (AU$67.8 million) was in areas relevant to conservation. However, of this relatively modest funding, 40% of conservation projects addressed questions classified as highly relevant, and 11.4% dealt with Australia’s threatened terrestrial vertebrate fauna. Of the AU$2.5 billion grant investment by the Department of the Environment, 7.9% (AU$196.3 million) was relevant to fauna conservation but mainly for on-ground management (62.5%). However, 32.9% of projects were research highly relevant to conservation practice, and 18.8% dealt with Australia’s threatened terrestrial vertebrate fauna. The Cooperative Research Centres Program is a well funded system that has supported applied research relevant to wildlife conservation. However, the Program’s recent focus has been on commercial outcomes rather than the public good. The study provides support for the argument that greater investment by the Federal Government is needed if innovation in wildlife management is to have a solid evidence base.
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Frahm, I. "National HER2 testing program for breast cancer patients in Argentina." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 10566. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.10566.

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10566 Background: In Argentina, before 2003 few pathologists performed HER2 testing, using different non-standardized Inmuno-Histo-Chemical (IHC) methods with dubious and non-reproducible results and also leaving some parts of the country without HER2 diagnosis Objective: HER2 has a key role in breast cancer management, so the aim of the study was to settle a National HER2 testing Program to permit access to standardized HER2 detection all over the country, and whenever possible, to determine hormonal receptors. Methods: In August 2003, 13 pathologists formed a cooperative group and created a national framework to train and set HER2 diagnostic centres in each country region. A coordinator responsible for coaching and evaluating centres and two technical consultants in charge of quality control and technique standardization were designated. In February 2004, the program was launched. Tumors were received from 82 oncologists and breast surgeons, using a private courier created “ad hoc”. HER2 was analyzed by IHC test between February 2004 and November 2005 and performed using policlonal antibody anti Her 2 (DAKO), microwave antigenic recovery, detection system EnVision (Dako) and developed with diaminobenzidine. Results were interpreted as HercepTest guidelines. ER/PR were screened by IHC analyses. Results: 2285 HER2 tests were performed: HER2 was over-expressed (score 3+) in 18% of tumors (408). 136 (6%) samples were score 2+, 407 (18%) score 1+ and 1334 (58%) score 0. In 1532/2285 (67%) of tumor specimens ER and PR status could be determined. Conclusions: Founding HER2 National Program allowed access to HER2 testing all over the country with a standardized and reproducible technique. HER2 prevalence in our sample (18%) is similar to those previously published. Although international algorithms recommend FISH assay to HER2 2+ tumors, our Program can not afford it. ER/PR expression were decreased significantly in HER2 3+ vs. HER2 - tumors: 53% vs. 64%: p = 0.002. HER2 3+ were associated with higher levels ER/PR: 38% vs. 24% in HER2 - tumors (p < 0.001). [Table: see text] No significant financial relationships to disclose.
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Sandall, Jean, Ray Cooksey, and Vic Wright. "A Systems Approach to Identifying and Managing Opportunities and Constraints to Delivering Innovation Policy for Agriculture: An Analysis of the Australian Cooperative Research Centres (CRC) Program." Journal of Agricultural Education and Extension 17, no. 5 (October 2011): 411–23. http://dx.doi.org/10.1080/1389224x.2011.596418.

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Lupi, Chiara, Luana Evangelista, Valentina Favoni, Antonio Granato, Andrea Negro, Lanfranco Pellesi, Raffaele Ornello, et al. "Rare primary headaches in Italian tertiary Headache Centres: Three year nationwide retrospective data from the RegistRare Network." Cephalalgia 38, no. 8 (May 12, 2018): 1429–41. http://dx.doi.org/10.1177/0333102418768824.

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Background Rare primary headaches are mainly included in Chapters 3, Trigeminal autonomic cephalalgias, and 4, Other primary headache disorders, Part One of the International Classification of Headache Disorders 3rd edition. Epidemiological data are scarce, mostly emerging from case series or small studies, with the exception of cluster headache. In order to overcome the knowledge gap about rare primary headaches, the RegistRare Network was launched in 2017 to promote research in the field. Methods A retrospective cohort study including patients who, from April 30, 2014 to May 1, 2017, visited seven Italian tertiary Headache Centres, was undertaken to estimate in that clinical setting prevalence and incidence of headaches included in Chapters 3 and 4, Part One of the International Classification of Headache Disorders 3rd edition. Prevalent headache is defined as a headache recorded within the study timeframe, regardless of when the diagnosis was made. Incident headache is defined as a headache diagnosed for the first time in the patient during the study period. Results Twenty thousand and eighty-three patients visited the participating centres, and 822 (4.1%) prevalent cases, of which 461 (2.3%) were incident cases, were registered. Headaches listed in Chapter 3 affected 668 patients, representing 81.3% of the total number of prevalent cases. Headaches listed in Chapter 4 affected 154 patients and represent 18.7% of the total number of prevalent cases. Cluster headaches represent the most frequently diagnosed rare headaches (70.4%). For 13 entities out of 20, no cases were registered in more than 50% (n ≥ 4) of the centres, and for 14 entities more than 50% of diagnoses were incident. Conclusions This large, multicentre study gives the first wide-ranging snapshot of the burden in clinical practice of rare headaches and confirms that cooperative networks are necessary to study rare headaches, as their prevalence is often very low. The launch of a disease registry by the RegistRare Network will favour research in this neglected population of headache patients. Trial registration NCT03416114.
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Dumas, Lucy, Rebecca Bowen, John Butler, and Susana Banerjee. "Under-Treatment of Older Patients with Newly Diagnosed Epithelial Ovarian Cancer Remains an Issue." Cancers 13, no. 5 (February 25, 2021): 952. http://dx.doi.org/10.3390/cancers13050952.

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Older women with ovarian cancer have disproportionately poorer survival outcomes than their younger counterparts and receive less treatment. In order to understand where the gaps lie in the treatment of older patients, studies incorporating more detailed assessment of baseline characteristics and treatment delivery beyond the scope of most cancer registries are required. We aimed to assess the proportion of women over the age of 65 who are offered and receive standard of care for first-line ovarian cancer at two UK NHS Cancer Centres over a 5-year period (December 2009 to August 2015). Standard of care treatment was defined as a combination of cytoreductive surgery and if indicated platinum-based chemotherapy (combination or single-agent). Sixty-five percent of patients aged 65 and above received standard of care treatment. Increasing age was associated with lower rates of receiving standard of care (35% > 80 years old versus 78% of 65–69-year-olds, p = 0.000). Older women were less likely to complete the planned chemotherapy course (p = 0.034). The oldest women continue to receive lower rates of standard care compared to younger women. Once adjusted for Federation of Gynaecology and Obstetrics (FIGO) stage, Eastern Cooperative Oncology Group (ECOG) performance status and first-line treatment received, age was no longer an independent risk factor for poorer overall survival. Optimisation of vulnerable patients utilising a comprehensive geriatric assessment and directed interventions to facilitate the delivery of standard of care treatment could help narrow the survival discrepancy between the oldest patients and their younger counterparts.
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Bisogno, Gianni, Giovanni Cecchetto, and Andrea Ferrari. "Very Rare Tumours in Paediatric Age — From ‘Tumori Rari in Età Pediatrica’ to the European Cooperative Study Group for Paediatric Rare Tumours." European Oncology & Haematology 08, no. 02 (2012): 130. http://dx.doi.org/10.17925/eoh.2012.08.02.130.

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Very rare tumours (VRTs) in paediatric age are a heterogeneous group of cancers very rarely encountered in daily practice, even in large paediatric oncology centres. Some of them are typical of paediatric age, such as pleuropulmonary blastoma or pancreatoblastoma; others are typically found in adulthood, such as carcinomas and melanoma. With the objective of improving the research on, and management of, paediatric VRTs, a national study group was founded and the Tumori Rari in Età Pediatrica (Rare Tumours in Paediatric Age [TREP]) project was launched in Italy in 2000. For the purposes of this project, VRTs have been defined as “any solid malignancy characterized by an annual incidence of <2 cases/million children and not considered in other clinical trials”. From January 2000 to December 2011, 652 patients <18 years of age were registered in the TREP database. This article presents the experience gathered so far and underlines the need to develop international collaborations dedicated to paediatric VRTs. With this aim, national groups from Italy, Germany, France, Poland and the UK have created, in June 2008, a new collaborative group named European Cooperative Study Group for Paediatric Rare Tumours (EXPeRT).
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Cattle, Stephen R., and Damien J. Field. "A review of the soil science research legacy of the triumvirate of cotton CRC." Crop and Pasture Science 64, no. 12 (2013): 1076. http://dx.doi.org/10.1071/cp13223.

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For nearly two decades (1994–2012) a series of three consecutive Cooperative Research Centres (CRC) dealing with cotton production provided the impetus and financial support for a substantial body of soil science research in eastern and northern Australia. Focusing on the most commonly utilised soil for irrigated crop production, the Vertosol, CRC-affiliated soil researchers undertook detailed soil inventories of cotton-growing valleys in New South Wales, and tackled a range of applied soil research questions that faced the entire Australian cotton industry. Across the broad categories of soil mapping and characterisation, soil physical condition, salinity and sodicity, soil chemical fertility, and soil carbon and biota, some 120 CRC-affiliated research papers were published in peer-reviewed journals during the years of the CRC. Findings from this body of research were fed back to the industry through conferences, extension workshops and materials, and to a lesser extent, the peer-reviewed publications. In certain cases, underpinning basic research was carried out concurrently with the more applied research, meaning that the cotton CRC were effectively supporting advances in the discipline of soil science, as well as in sustainable cotton production. A feature of the soil research portfolio over the span of the three cotton CRC was that priorities shifted according to the interplay of three factors; the natural maturation of research topics and the concomitant evolution of cotton farming systems, the rising importance of environmental implications of agricultural land use, and the emergence of carbon as a national research priority. Furthermore, the commitment of the CRC to education resulted in the involvement of undergraduate and postgraduate university students in all aspects of the soil research effort. A legacy of the triumvirate of cotton CRC is a wide-ranging body of both applied and basic knowledge regarding the physical, chemical and biological attributes of Australian Vertosols used for irrigated agriculture.
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Galligioni, E., S. Forti, F. Berloffa, O. Caffo, A. Ferro, C. Eccher, A. Caldara, V. Murgia, and B. Soini. "Real-time quality assessment of cancer care through information technology instruments incorporated into routine clinical practice." Journal of Clinical Oncology 27, no. 15_suppl (May 20, 2009): 6620. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.6620.

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6620 Background: Information technology may provide complete and timely data, to monitor process-based and outcomes measurements, which are crucial for health care improvement. Since June 2000, we have developed an Electronic Oncological Patient Record (EOPR), which is routinely used in our Department, providing a powerful link between computer-based technology and clinical practice (Ann. Oncol. 2008). Recently EOPR was implemented with a Clinical Instrument Panel (OncoQual) which enables oncologists to explore clinical data and perform real-time process and outcome measurements, by applying a flexible module to formulate complex population queries. Methods: To evaluate the performance of OncoQual in our pts, we chose as quality indicator, the adherence to ASCO recommendations on adjuvant endocrine therapy (ET), in hormone receptor positive (HR+) breast cancer (BC) pts. In particular, we assessed pts treated from 2000 to 2004 for Tamoxifen (TAM) and pts treated from 2006 to 2007 for Aromatase Inhibitors (AIs). Furthermore TAM results were compared with the adjuvant treatments modalities of 77 italian centres, reported from a cooperative group (NORA) for the same period. Results: The results are shown in the table. Patients characteristics and Tam use in our series, were similar to those of the NORA group, while TAM use decreased and AIs increased in the 2006–07 series, as expected. It took few hours to collect and analyzed our series, which can be easily updated and adapted to different requirements. Conclusions: Our experience shows the feasibility of incorporating real-time process-based measurements into daily practice, to provide self assessment for continuous quality of care monitoring and improving. [Table: see text] No significant financial relationships to disclose.
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Alexander, Graeme. "Cooperative Research Centre for Polymers." Seikei-Kakou 13, no. 6 (June 20, 2001): 367–69. http://dx.doi.org/10.4325/seikeikakou.13.367.

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Bindon, B. M., H. M. Burrow, and B. P. Kinghorn. "Communication, education and training strategies to deliver CRC outcomes to beef industry stakeholders." Australian Journal of Experimental Agriculture 41, no. 7 (2001): 1073. http://dx.doi.org/10.1071/ea00066.

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At the commencement of the Cooperative Research Centre for the Cattle and Beef Industry (Meat Quality) participating scientists were encouraged to anticipate the methods and channels that might be used to deliver the Cooperative Research Centre’s research outcomes to beef industry end-users. This important step was seen as the completion of the process, which began with the beef industry issue, leading then to formulation of the Cooperative Research Centre concept, initiation of the research program, completion of research and finally commercialisation or delivery of products and processes to industry. This paper deals with techniques, institutions and commercial arrangements employed to achieve delivery and adoption of diverse outcomes of the Cooperative Research Centre.
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Jean-Christophe, Ianotto, Jean-Jacques Kiladjian, Marta Sobas, Parvis Sadjadian, Lee-Yung Shih, Maria Bieniaszewska, Ilona Seferynska, et al. "Myeloproliferative Neoplasms in Patients below 25 Years Old at Diagnosis: A Retrospective International Cooperative Work." Blood 132, Supplement 1 (November 29, 2018): 1759. http://dx.doi.org/10.1182/blood-2018-99-112374.

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Abstract Myeloproliferative neoplasms (MPN) are most common in old people (>60 years) and are rarely identified in children and young adults where information about complication rates and long-term data are lacking. To improve our knowledge, we retrospectively collected cases of young patients diagnosed with MPN before 25 years of age and analysed data of their disease to date, including vascular events and disease evolution. Data were collected in 29 hospital centres from 12 countries. Between 1971 and 2018, 335 young patients were diagnosed for an MPN before the age of 25. They were mostly females (n=246; 73.4%) with a median age of 20.3 years at diagnosis (2.5 months-25 years). Essential thrombocythemia was diagnosed in 234 patients (69.8%), polycythemia vera in 60 (17.9%) and myelofibrosis or unclassified MPN in 41 (12.3%). Most of the diagnoses were made following a coincidental blood count analysis (n=75; 51%) some based on symptoms (n=57; 38.8%) or thrombotic events (n=15; 10.2%). In terms of complications before or at diagnosis, 31 (9.3%) patients experienced thrombosis, mostly venous (75%) and 13 (3.9%) had hemorrhage. At diagnosis, the median leukocyte count was 9x109/l (range: 3-22.8), median hemoglobin count 140 g/l (65-220) and median platelet count 900x109/l (99-3290). To assess the diagnosis, 158 patients (47.2%) had had bone marrow aspirates and 214 (63.9%) a bone marrow biopsy. Mutational status was available in 319 (90%) cases: 194 (60.8%) were JAK2V617F positive, 48 (15%) had a calreticulin mutation, 76 (23.8%) were triple-negative and 1 patient had MPL mutation. The median follow-up of the cohort was 7.7 years (0-46.8) with 134 patients (40%) having follow-up for more than 10 years. 81 female patients (32.9%) experienced pregnancies. During this period, 295 patients (88%) received at least one drug for their MPN: 254 patients (77.2%) received antithrombotic drug and 222 patients (66.5%) a cytoreductive drug. As first line of treatment, hydroxycarbamide was given to 111 patients (50%) whereas anagrelide was given to 56 patients (25.2%) and interferon to 50 (22.5%). During the follow-up, 97 patients (29%) experienced at least one complication. In terms of cardiovascular events, 38 (11.3%) patients experienced thromboses with 50 events in total (recurrences in 12 cases), including 33 venous events (66%) of which 15 were localized in the splanchnic territory (45.5%). Hemorrhagic events were recorded in 34 cases (10.1%). During the follow-up, 39 patients (11.6%) have evolved: 11 from ET to PV (28.2%), 26 into MF (66.7%) and 2 into AML (5.1%). All evolutions were exclusive: one event per patient. At the time of the analysis, 66 patients (19.7%) were declared as lost of follow up and 4 were dead (1.2%). This is the largest cohort of patients aged below 25 years at the time of diagnosis demonstrates that despite their youth most of them (88%) received drug(s) for the management of their MPN. There was a high incidence of complications (29%), with vascular events and disease evolution occurring at equal frequency although death was uncommon (1.2%). Rates of events were disease evolution: 1.51/100pts/y; thromboses: 1.47 and hemorrhages: 1.32. No specific national or international guidance exists for MPN patients of this age; but our data suggest that these are not benign conditions and patients need to be carefully followed and treated. Table. Table. Disclosures Kiladjian: Celgene: Membership on an entity's Board of Directors or advisory committees; Novartis: Membership on an entity's Board of Directors or advisory committees, Research Funding; AOP Orphan: Membership on an entity's Board of Directors or advisory committees, Research Funding. Giraudier:Novartis: Research Funding. Griesshammer:Novartis: Membership on an entity's Board of Directors or advisory committees, Speakers Bureau. Harrison:Novartis: Consultancy, Honoraria, Research Funding, Speakers Bureau; Celgene: Consultancy, Honoraria, Speakers Bureau; Roche: Consultancy, Honoraria; Gilead: Honoraria, Speakers Bureau; CTI BioPharma: Consultancy, Honoraria.
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Zeng, Yong-Yi, Wu-hua Guo, Zhibo Zhang, Xi Shi, Yongjie Su, Qinghe Cai, and Jianyang Peng. "A real-world study of camrelizumab in the treatment of hepatocellular carcinoma." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e16121-e16121. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e16121.

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e16121 Background: Programmed cell death protein‐1(PD-1) targeted immunotherapy is a promising treatment strategy for advanced hepatocellular carcinoma. Anti-PD-1 inhibitor camrelizumab showed antitumour activity in phase II studies of advanced hepatocellular carcinoma, with manageable toxicities. This study evaluates safety and efficacy of camrelizumab in patients with advanced hepatocellular carcinoma. Methods: This is a multicentre, real‐world trial done at thirty-three centres in Fujian Province, China. Eligible patients were aged 18 to 75 years was diagnosed by China Liver Cancer Staging(CNLC) 2019 clinical diagnostic criteria or with a histological or cytological diagnosis of advanced hepatocellular carcinoma, unresectable or had progressed on or were intolerant to previous systemic treatment, and had an Eastern Cooperative Oncology Group performance score of 0-1. Patients were received camrelizumab 200 mg intravenously every 2 weeks plus other treatments, such as molecular targeted drug, transcatheyer artetial chemoembolization, radiotherapy and chemotherapy. The primary endpoints were progression-free survival. Safety was analysed in all treated patients. Follow-up is ongoing. Results: Between Mar 12, 2020, and Dec 25, 2020, 63 patients were screened for eligibility, of whom 41 eligible patients received camrelizumab were recruited and among whom 15 received apatinib, 16 received lenvatinib, 2 received sorafenib and 1 received regorafenib. Median followup was 5.28 months (IQR 1.63–10.20). Objective response was reported in 12 (29.3%; 95% CI 16.1–45.5) of 41 patients. Disease control was reported in 34 (82.9%; 95% CI 67.9–92.8) of 41 patients. The median PFS was not reached, and expected more than 9 months. Grade 3 or 4 treatment-related adverse events occurred in 21 (51.2%) of 41 patients; the most common were increased gamma-glutamyltransferase (15 [36.6%]) and increased aspartate aminotransferase (7 [17%]). One death was judged by the investigators to be potentially treatment-related (due to upper gastrointestinal bleeding). Conclusions: Camrelizumab showed promising efficacy and safety in pretreated Chinese patients with advanced hepatocellular carcinoma, and might represent a new treatment option for these patients. Clinical trial information: ChiCTR2000041405. Research Sponsor: Jiangsu Hengrui Medicine Co., Ltd. Clinical trial information: ChiCTR2000041405.
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Das, Prantik, Anand Sharma, Ruchir Bhandari, JunHao Lim, Aruni Ghose, Jessica Davies, Ajith Nair, et al. "A multicenter real-life U.K. study of use of immunotherapeutic agents in metastatic urothelial cancer." Journal of Clinical Oncology 40, no. 6_suppl (February 20, 2022): 504. http://dx.doi.org/10.1200/jco.2022.40.6_suppl.504.

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504 Background: First-line chemotherapy for patients with cisplatin-ineligible metastatic urothelial carcinoma (mUC) is associated with short response duration and high toxicity. Pembrolizumab(PEM) and atezolizumab (ATZ) are associated with long-term, durable remissions as a first-line treatment of cisplatin-ineligible, PD-L1-positive patients with mUC. For patients who progressed during or after platinum-based chemotherapy, Immunotherapy also prolongs survival with less toxicity and better quality of life compared with further lines of chemotherapy. There have been no studies directly comparing the effectiveness of PEM to ATZ in mUC patients. Methods: A cohort of 112 patients from 3 UK centres were included. 62, previously untreated cisplatin ineligible mUC patients who showed PDL1 positivity were given either ATZ or PEM once every 3 weeks until progression. 49 patients who had initial platinum based chemotherapy subsequently had ATZ or PEM as second line treatment following their disease progression The primary endpoint was Overall Survival(OS) and secondary endpoints included objective rate(ORR), response duration and safety. Results: The median age was 69 ( Interquartile range 43-91) and 23% were female and 77% were male. Among, patients who received immunotherapy 1st line, 82% had baseline renal impairment(GFR < 60), and 18% had Eastern Cooperative Oncology Group performance status 2. For chemo naïve patients, median OS was 11.5 months for PEM and 5 months for ATZ respectively. ORR was 22 % for ATZ vs 50% for PEM and median duration of treatment was 4.5 and 2.5 months for PEM and ATZ respectively. When used in 2nd line median OS is 7 months for ATZ irrespective of PDL1 status and not reached for PEM yet. Grade 2 and above toxicities were reported in 18 % ATZ patients vs 10% in PEM patients, commonest were pneumonitis, tiredness, hepatitis and dermatitis. No treatment related deaths were reported. Conclusions: This study suggests that pembrolizumab has higher response rate and better survival compared to atezolizumab in cisplatin-ineligible patients with mUC and also in the 2nd line setting after disease progression following platinum based agents. Both agents were well tolerated.
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Becker, J. C. "Diagnostics and therapy of Merkel cell carcinoma (MCC) in Germany— Guidelines and reality." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 18564. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.18564.

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18564 Background: Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous malignancy of the elderly. Due to its low incidence, current guidelines for diagnostic and therapeutic interventions are based on low levels of evidence. Moreover, it is unclear how strictly these guidelines are followed in the management of MCC patients. Methods: A review of MCC patients treated in 15 selected centres of the Dermatologic Cooperative Oncology Group between 1998 and 2004, i.e. when the initial version of national guidelines were valid, identified 150 patients of whom tumor- and treatment-related factors were analyzed for association with recurrence. Results: Initial tumour staging was completed in about 1/3rd of MCC patients in accordance with the guidelines (i.e. ultrasound of the abdomen and the regional lymph nodes, chest X-ray), in 1/3rd using an intensified regimen, and in the remaining patients was incomplete. Staging revealed that 82.5% of the patients were in stage I, 16.1% in stage II and 1.4% in stage III at the time of primary diagnosis of MCC. With respect to initial therapy, the mean surgical excision margin was 1.86 cm (instead of 3 cm) and adjuvant radiation was applied in 40% of the patients. Pathologic staging of the draining nodal basin was performed in 37 patients (24.6%), and 24.2% of these had node-positive disease. 56 patients (37.3%) recurred and the median time to recurrence was 10 months. Local and/or loco-regional recurrence developed in 29 and 33 patients, respectively; in 22 patients distant metastases occurred. While age, gender, tumour diameter and histological type were not significantly correlated with recurrence, therapeutic measures were, i.e. lower surgical margins and lack of adjuvant radiation were associated with an increased recurrence rate. Conclusions: Our study demonstrates that the current guidelines were only partially implemented in the clinical routine. This is particularly worrisome as our data indicate that MCC treatment in accordance to the guidelines results in an improved control of the disease. No significant financial relationships to disclose.
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Arumugam, Nalini, Kaarthiyainy Supramaniam, Geraldine De Melle, and Laura Christ Dass. "Autonomous English as a second language writing through group-writing transformations." Social and Management Research Journal 10, no. 2 (December 2, 2013): 25. http://dx.doi.org/10.24191/smrj.v10i2.5225.

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The study investigated the effects of group-writing on learners at an institution of higher learning who worked in cooperative based writing groups (group-writing henceforth) and individually. 117 undergraduates participated in this quasi-experimental study for 14 weeks. The learners were grouped in groups of three or four. A mixed-design approach was employed in data collection. Questionnaires were administered and semi-structured interviews were carried out to elicit information. The results indicated a favourable view of group-writing as an instructional approach in English as a second language (hereafter ESL) writing classrooms. The learners in the group-writing cooperated with each other on assigned tasks. The results revealed that there was a significant difference between the experiment and control groups, whereby the m 39.3 772 value for the experimental group while m 28.1149 for the control group at (0<,05). This obviously shows that the learners in the experimental group have out performed the learners who worked individually. As they had more opportunities to work together, they built a strong perception of group cohesion and responsibility for other's learning which gradually helped them become autonomous writers. This study adds insights into pedagogical approaches used in ESL centres of higher learning and recommendations are suggested for further research.
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Jaržemskis, Andrius. "RESEARCH ON PUBLIC LOGISTICS CENTRE AS TOOL FOR COOPERATION." TRANSPORT 22, no. 1 (March 31, 2007): 50–54. http://dx.doi.org/10.3846/16484142.2007.9638096.

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This paper focuses on logistics centre concept and benefits for users. Intermodal benefit, forwarders impact, IT solutions, new transport flows due to synergy, better supply chain management, additional services, cost sharing, economies of scale, quality of the services, know‐how, joint marketing impact, and benefit for growth of third‐party logistics services are presented. The main bottlenecks such as duration of planning logistics centres process, pressure to land use for other purposes and problems caused by legislation are described. Results of pilot study of benefits from business cooperation are presented and concluded as well.
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Turpin, Tim, Sam Garrett-Jones, and Kieren Diment. "Scientists, Career Choices and Organisational Change: Managing Human Resources in Cross Sector R&D Organisations." Journal of Management & Organization 11, no. 2 (March 2005): 13–26. http://dx.doi.org/10.1017/s1833367200004260.

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ABSTRACTThe resource-based view of the firm has drawn attention to the role of human resources in building innovative capacity within firms. In ‘high technology’ firms, scientific capability is a critical factor in achieving international competitiveness. Science, however, is a costly business and many firms are entering into cross-sector R&D partnerships in order to gain access to leading edge scientific capability. The Australian Cooperative Research Centres (CRC) program is typical of the ways many governments are seeking to promote such cross-sector R&D collaboration. Scientists are key resources in these organisational arrangements. However, there is only fragmentary information available about why and when scientists choose to work in these cross-sector organisations rather than others, or the impact of changing funding regimes on their career choices. Similarly, there has been little research into the impact of such partnerships and career choices on the organisations in which scientists work. This paper presents some findings from two new ARC funded studies in Australia designed to investigate the careers of scientists and the organisational and career implications of participation in cross-sector R&D collaboration. One of our findings is that CRCs may not endure as long term ‘hybrid’ organisational arrangements as some observers have suggested, but rather remain as transitional structure influencing the partners involved and the careers of scientists. This has important implications for the managers of CRCs as well as those responsible for partner organisations.
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Turpin, Tim, Sam Garrett-Jones, and Kieren Diment. "Scientists, Career Choices and Organisational Change: Managing Human Resources in Cross Sector R&D Organisations." Journal of the Australian and New Zealand Academy of Management 11, no. 2 (March 2005): 13–26. http://dx.doi.org/10.5172/jmo.2005.11.2.13.

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ABSTRACTThe resource-based view of the firm has drawn attention to the role of human resources in building innovative capacity within firms. In ‘high technology’ firms, scientific capability is a critical factor in achieving international competitiveness. Science, however, is a costly business and many firms are entering into cross-sector R&D partnerships in order to gain access to leading edge scientific capability. The Australian Cooperative Research Centres (CRC) program is typical of the ways many governments are seeking to promote such cross-sector R&D collaboration. Scientists are key resources in these organisational arrangements. However, there is only fragmentary information available about why and when scientists choose to work in these cross-sector organisations rather than others, or the impact of changing funding regimes on their career choices. Similarly, there has been little research into the impact of such partnerships and career choices on the organisations in which scientists work. This paper presents some findings from two new ARC funded studies in Australia designed to investigate the careers of scientists and the organisational and career implications of participation in cross-sector R&D collaboration. One of our findings is that CRCs may not endure as long term ‘hybrid’ organisational arrangements as some observers have suggested, but rather remain as transitional structure influencing the partners involved and the careers of scientists. This has important implications for the managers of CRCs as well as those responsible for partner organisations.
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45

Truscott, Graham, and Philip Thomas. "A strategy for achieving innovation through Sheep Cooperative Research Centre research and development." Animal Production Science 50, no. 12 (2010): 1145. http://dx.doi.org/10.1071/an10149.

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The Sheep Cooperative Research Centre’s role to facilitate the transformation of the Australian sheep industry is complicated by the extensive nature of the industry across some 31 000 small to medium farming enterprises, linking to both sheep meat and wool supply chains. Close integration of the market with research and adoption through a product development focus is enabling a staged product development process while providing the management flexibility needed for development of each product type within target markets. This paper presents the basis of the New Product Development Framework and the adoption strategies used across the Sheep Cooperative Research Centre programs to accelerate utilisation of products developed out of research. These strategies include: communication; training coordination; network engagement and use of key influencers; supply chain engagement and the use of specific adoption research tools.
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Bell, Alan W. "Animal science Down Under: a history of research, development and extension in support of Australia’s livestock industries." Animal Production Science 60, no. 2 (2020): 193. http://dx.doi.org/10.1071/an19161.

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This account of the development and achievements of the animal sciences in Australia is prefaced by a brief history of the livestock industries from 1788 to the present. During the 19th century, progress in industry development was due more to the experience and ingenuity of producers than to the application of scientific principles; the end of the century also saw the establishment of departments of agriculture and agricultural colleges in all Australian colonies (later states). Between the two world wars, the Council for Scientific and Industrial Research was established, including well supported Divisions of Animal Nutrition and Animal Health, and there was significant growth in research and extension capability in the state departments. However, the research capacity of the recently established university Faculties of Agriculture and Veterinary Science was limited by lack of funding and opportunity to offer postgraduate research training. The three decades after 1945 were marked by strong political support for agricultural research, development and extension, visionary scientific leadership, and major growth in research institutions and achievements, partly driven by increased university funding and enrolment of postgraduate students. State-supported extension services for livestock producers peaked during the 1970s. The final decades of the 20th century featured uncertain commodity markets and changing public attitudes to livestock production. There were also important Federal Government initiatives to stabilise industry and government funding of agricultural research, development and extension via the Research and Development Corporations, and to promote efficient use of these resources through creation of the Cooperative Research Centres program. These initiatives led to some outstanding research outcomes for most of the livestock sectors, which continued during the early decades of the 21st century, including the advent of genomic selection for genetic improvement of production and health traits, and greatly increased attention to public interest issues, particularly animal welfare and environmental protection. The new century has also seen development and application of the ‘One Health’ concept to protect livestock, humans and the environment from exotic infectious diseases, and an accelerating trend towards privatisation of extension services. Finally, industry challenges and opportunities are briefly discussed, emphasising those amenable to research, development and extension solutions.
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Jacobson, Galia, Ronen Fluss, Amira Dany-BenShushan, Talia Golan, Tikva Meron, Camilla Zimmermann, Laura A. Dawson, et al. "Coeliac plexus radiosurgery for pain management in patients with advanced cancer : study protocol for a phase II clinical trial." BMJ Open 12, no. 3 (March 2022): e050169. http://dx.doi.org/10.1136/bmjopen-2021-050169.

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IntroductionPancreatic cancer is characterised by severe mid-back and epigastric pain caused by tumour invasion of the coeliac nerve plexus. This pain is often poorly managed with standard treatments. This clinical trial investigates a novel approach in which high-dose radiation (radiosurgery) is targeted to the retroperitoneal coeliac plexus nerve bundle. Preliminary results from a single institution pilot trial are promising: pain relief is substantial and side effects minimal. The goals of this study are to validate these findings in an international multisetting, and investigate the impact on quality of life and functional status among patients with terminal cancer.Methods and analysisA single-arm prospective phase II clinical trial. Eligible patients are required to have severe coeliac pain of at least five on the 11-point BPI average pain scale and Eastern Cooperative Oncology Group performance status of two or better. Non-pancreatic cancers invading the coeliac plexus are also eligible. The intervention involves irradiating the coeliac plexus using a single fraction of 25 Gy. The primary endpoint is the complete or partial pain response at 3 weeks. Secondary endpoints include pain at 6 weeks, analgesic use, hope, qualitative of life, caregiver burden and functional outcomes, all measured using validated instruments. The protocol is expected to open at a number of cancer centres across the globe, and a quality assurance programme is included. The protocol requires that 90 evaluable patients" be accrued, based upon the assumption that a third of patients are non-evaluable (e.g. due to death prior to 3-weeks post-treatment assessment, or spontaneous improvement of pain pre-treatment), it is estimated that a total of 120 patients will need to be accrued. Supported by Gateway for Cancer Research and the Israel Cancer Association.Ethics and disseminationEthic approval for this study has been obtained at eight academic medical centres located across the Middle East, North America and Europe. Results will be disseminated through conference presentations and peer-reviewed publications.Trial registration numberNCT03323489.
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48

Gray, Denis O., and Eric Sundstrom. "Multi-Level Evaluation of Cooperative Research Centers." Industry and Higher Education 24, no. 3 (June 2010): 211–17. http://dx.doi.org/10.5367/000000010791657464.

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Two emergent conceptual models for fostering the development of innovative technology through applied science at Cooperative Research Centers (CRCs) – the Triple Helix and the science of team science – have proved highly productive in stimulating research into how the innovation process works. Although the two arenas for fostering innovation have much in common, there has been relatively little synergy, or even interaction, between the researchers who study them. In this paper the authors discuss a programme of research that has attempted to blend the two, by shedding light on team processes within Triple Helix CRCs. They report findings from CRCs in relation to the comparative characteristics of single-scientist and multi-scientist, team-based partnerships; collaborative processes among CRC scientists, sometimes involving ‘serial’ collaboration; and the role of spatial factors in team-based processes. The paper also explores the possibilities for exploiting the synergies between Triple Helix and science of team science for public policy, innovative practices and future research.
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49

Alpyspaeva, Galya A. "History of Activities of the Akmola District Union of Cooperatives (1917–1922)." Vestnik Tomskogo gosudarstvennogo universiteta, no. 464 (2021): 113–21. http://dx.doi.org/10.17223/15617793/464/13.

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Based on the analysis of the previously unused archival sources and research works on the history of Russian cooperation, the main areas of the activities of the Akmola District Union of Cooperatives in 1917–1922 are studied and generalized. In terms of methodology, the study is based on the works of ideologists of Russian cooperation (M.I. Tugan-Baranovsky, V.F. Totomianets, A.V. Chayanov, and others) and the original concepts they developed. The article analyzes the activities of the Union of Cooperatives of a particular micro-region: the number of employees, organizational structure and management, organization of industrial production, financial and social policies, cultural and educational activities. The author substantiates the role of the District Union of Cooperatives in the development of economic relations in the region and in the district peasant farms’ entry into the all-Russian market. Despite the difficult political circumstances and the relatively short period of existence (from August 1917 to the end of 1922), the Akmola District Union of Cooperatives became an economic and organizational center, contributed to the establishment and development of the consumer cooperation system not only in the district, but also in the region: it initiated the establishment of the regional Union of Steppe Cooperatives. In the conditions of the territorial remoteness from industrial centers and the underdeveloped transport infrastructure, the District Union of Cooperatives significantly facilitated and promoted the production activities of the peasants of the region connecting them with the market, expedited the involvement of Kazakh farms in the regional economy. The Union carried out an active social policy and diversified cultural and educational work, allocated significant amounts from its profits to the development of education in the district. According to the author, the activities of the Akmola District Union of Cooperatives can be considered as an integral part of the national cooperative movement, and its success was due to the application of the allRussian experience during the heyday of cooperation in the country.
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50

Bindon, B. M. "Genesis of the Cooperative Research Centre for the Cattle and Beef Industry: integration of resources for beef quality research (1993-2000)." Australian Journal of Experimental Agriculture 41, no. 7 (2001): 843. http://dx.doi.org/10.1071/ea00067.

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The Cooperative Research Centre for the Cattle and Beef Industry (Meat Quality) was formulated in 1992 by CSIRO, the University of New England (UNE), NSW Agriculture and Queensland Department of Primary Industries (QDPI) to address the emerging beef quality issue facing the Australian beef industry at that time: the demand from domestic and export consumers for beef of consistent eating quality. An integrated program of research involving meat science, molecular and quantitative genetics and growth and nutrition was developed. To meet the expectations of the Commonwealth of Australia, additional projects dealing with animal health and welfare and environmental waste generated by feedlot cattle were included. The program targeted both grain- and grass-finished cattle from temperate and tropical Australian environments. Integration of research on this scale could not have been achieved by any of the participating institutions working alone. This paper describes the financial and physical resources needed to implement the program and the management expertise necessary for its completion. The experience of developing and running the Cooperative Research Centre confirms the complexity and cost of taking large numbers of pedigreed cattle through to carcass and meat quality evaluation. Because of the need to capture the commercial value of the carcass, it was necessary to work within the commercial abattoir system. During the life of the Cooperative Research Centre, abattoir closure and/or their willingness to tolerate the Research Centre’s experimental requirements saw the Cooperative Research Centre operations move to 6 different abattoirs in 2 states, each time losing some precision and considerable revenue. This type of constraint explains why bovine meat science investigations on this scale have not previously been attempted. The Cooperative Research Centre project demonstrates the importance of generous industry participation, particularly in cattle breeding initiatives. Such involvement, together with the leadership provided by an industry-driven Board guarantees early uptake of results by beef industry end-users. The Cooperative Research Centre results now provide the blueprint for genetic improvement of beef quality traits in Australian cattle herds. Heritabilities of beef tenderness, eating quality, marbling, fatness and retail beef yields are now recorded. Genetic correlations between these traits and growth traits are also available. Outstanding sires for beef quality have been identified. Linked genetic markers for some traits have been described and commercialised. Non-genetic effects on beef quality have been quantified. Australian vaccines against bovine respiratory disease have been developed and commercialised, leading to a reduction in antibiotic use and better cattle performance. Sustainable re-use of feedlot waste has been devised.
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