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Academic literature on the topic 'Convulsions'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 July 2024

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Journal articles on the topic "Convulsions"

1

Cinbiş, Mine. "Febrile Convulsions." European Journal of Therapeutics 10, no. 1, 2 (January 1, 1999): 46–52. http://dx.doi.org/10.58600/eurjther.1999-10-1-2-1518-arch.

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Febrile convulsions are the most common convulsive disorder in childhood foond in 2-5% of children who are younger !han five years. it is most common between 14th-181h months of life. Recently the roles of zinc, melatonine, arginine, vasopressine, and enkephalins in the ethiopathogenesis of FK have been postulated. The progress of fever, fluid and electrolyte imbalance, bacterial toxins, using of high dose penicilline and antihistaminics are predisposing factors. Human Herpes Virus type-6 can also cause recurrent febrile convulsions. Lumbar puncture should be done in ali cases with febrile convulsion who are younger than one year to rule out meningitis. EEG is not necessary in simple febrile convulsions. Recurrence rate of febrile convulsion is approximately 33%. The incidence of recurrence is 50% in the first six months and 90% in the first year after the first attack. lf the first attack occurred before one year of age, the recurrence rate is more than 50%. A positive history of febrile convulsion in first degree relatives, moderately high fever, being of first child of the family, and having the convulsion before one year old are the most important factors increasing the recurrence rate. The risk of epilepsy is approximately 4% in children with febrile convulsions. The most important factors in developing epilepsy are focal seizures, long duration of convulsions and delayed pscychomotor development.

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Anigilaje, Emmanuel Ademola, and Omolara Olufunmilayo Anigilaje. "Childhood Convulsion: Inquiry about the Concerns and Home Management among Mothers in Tegbesun, a Periurban Community in Ilorin, Nigeria." ISRN Pediatrics 2012 (November 20, 2012): 1–6. http://dx.doi.org/10.5402/2012/209609.

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Background. The fear and panic felt by most parents when their child convulsed made them apply all sorts of management. Objective. This study evaluated the concerns and home management of childhood convulsions among mothers in Tegbesun, a periurban community in Ilorin, Nigeria. Methods. A ten-week cross-sectional study comprising 500 mothers interviewed using a structured questionnaire. Results. Fear of death was the commonest concern (450, 90%) among mothers. For a witnessed convulsion, the majority took the child to the hospital (414, 82.8%). Cow’s urine concoction (74, 87.1%) was the most common item administered to a convulsing child. Putting the hand and/or a spoon into the mouth of the convulsing child was the commonest unwholesome practice (74, 61.2%). None of the subjects safely put the convulsing child on his/her side. Conclusions. Maternal concerns are precursors of mismanagement of childhood convulsions, and health education was undertaken at the end of the study.

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Malcolm, Cari, Pat Hoddinott, Emma King, Smita Dick, Richard Kyle, Philip Wilson, Emma France, Lorna Aucott, and Stephen W. Turner. "Short-stay urgent hospital admissions of children with convulsions: A mixed methods exploratory study to inform out of hospital care pathways." PLOS ONE 19, no. 4 (April 1, 2024): e0301071. http://dx.doi.org/10.1371/journal.pone.0301071.

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Objective To inform interventions focused on safely reducing urgent paediatric short stay admissions (SSAs) for convulsions. Methods Routinely acquired administrative data from hospital admissions in Scotland between 2015–2017 investigated characteristics of unscheduled SSAs (an urgent admission where admission and discharge occur on the same day) for a diagnosis of febrile and/or afebrile convulsions. Semi-structured interviews to explore perspectives of health professionals (n = 19) making referral or admission decisions about convulsions were undertaken. Interpretation of mixed methods findings was complemented by interviews with four parents with experience of unscheduled SSAs of children with convulsion. Results Most SSAs for convulsions present initially at hospital emergency departments (ED). In a subset of 10,588 (11%) of all cause SSAs with linked general practice data available, 72 (37%) children with a convulsion contacted both the GP and ED pre-admission. Within 30 days of discharge, 10% (n = 141) of children admitted with afebrile convulsions had been readmitted to hospital with a further convulsion. Interview data suggest that panic and anxiety, through fear that the situation is life threatening, was a primary factor driving hospital attendance and admission. Lengthy waits to speak to appropriate professionals exacerbate parental anxiety and can trigger direct attendance at ED, whereas some children with complex needs had direct access to convulsion professionals. Conclusions SSAs for convulsions are different to SSAs for other conditions and our findings could inform new efficient convulsion-specific pre and post hospital pathways designed to improve family experiences and reduce admissions and readmissions.

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Abdulsahib, Waleed K., Sarmed H. Kathem, Mohanad Y. Al-Radeef, and Layth S. Jasim. "Mentha piperita Oil Exerts an Antiepileptic Effect in Pilocarpine and Pentylenetetrazol-Induced Seizures in Mice." Veterinary Medicine International 2022 (September 22, 2022): 1–5. http://dx.doi.org/10.1155/2022/4431317.

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Introduction. Epilepsy is a progressive, chronic neurological disorder characterized by recurrent seizures. Peppermint (Mentha piperita L.) (MP) is one of the most commonly ingested herbal teas or tisanes with a single component. Aim. We aimed to assess the potential antiepileptic and neuroprotective features of MP essential oil (MPO) in pilocarpine (P) and pentylenetetrazol (PTZ) models of epilepsy. Methods. The study used eight groups of mice to assess the anticonvulsant activity of MPO in both the P and PTZ acute models in mice. P (350 mg/kg, i.p.) was given 30 minutes after MPO (1.6, 3.2, and 6.4 ml/kg, i.p.). As a positive control group, diazepam (1 mg/kg, i.p) was used. PTZ (95 mg/kg, i.p.) was given 30 minutes after MPO (6.4 ml/kg, i.p.). The first convulsion’s latency time, the number of convulsions, the latency time to death, and the percentage of deaths were calculated in all groups. Results. MPO significantly ( P < 0.05 ) increases the first convulsion’s latency time and the death’s latency time. Moreover, the essential oil significantly decreases the number of convulsions and reduces the mortality rate compared to the negative control group. Conclusion. MPO at 3.2 and 6.4 ml/kg doses can reduce the percentage and the number of convulsions and increase the latency time of both the first convulsion and death so that it can be used as a supplement in the treatment of epilepsy.

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Bharadwaj, Aashish, Ashwani Sharma, Talever Singh, Devender Pathak, Tarun Virmani, Girish Kumar, Anjali Sharma, and Abdulsalam Alhalmi. "Attenuation of Strychnine-Induced Epilepsy Employing Amaranthus viridis L. Leaves Extract in Experimental Rats." Behavioural Neurology 2023 (March 14, 2023): 1–10. http://dx.doi.org/10.1155/2023/6684781.

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Objective. Epilepsy is one of the most prevalent neurological illnesses defined by periodic seizures with or without loss of consciousness caused by aberrant neural activity. There are many allopathic medications available for the treatment of epilepsy such as phenytoin (PHY), but the side effects are a major concern. Therefore, the present study involved the evaluation of the pharmacological significance of Amaranthus viridis L. extract (EAV) in the management of strychnine (STR)-induced epilepsy. Method. STR (3.5 mg/kg, i.p.) was injected into male rats 30 minutes after the pre-treatment of a standard drug (PHY: 20 mg/kg) and the two doses of EAV (EAV-200 and EAV-400 mg/kg, p.o.) to the respective groups to cause the convulsions. The anti-convulsant effect of EAV-200 and EAV-400 against STR-induced convulsion in rats was investigated in terms of convulsion onset, duration of convulsions, number of convulsions, and convulsion score. Furthermore, the mitochondrial function and integrity in the brain’s prefrontal cortex (PFC) were also estimated. Results. EAV-400 significantly increased the onset of convulsion from 61.67 ± 3.051 to 119.2 ± 2.738 and reduced the STR-induced duration of convulsions from 144.8 ± 3.582 to 69.17 ± 3.736 , number of convulsions from 4.000 ± 0.1592 to 1.533 ± 0.1542 , and convulsion score from 5.000 ± 0.3651 to 2.833 ± 0.3073 in rats. EAV-400 significantly attenuated the STR-induced decrease in the mitochondrial function and integrity of the rat PFC. In rats, EAV-400 significantly accelerated the onset of convulsions while decreasing the STR-induced duration, frequency, and score. Conclusion. Based on investigational findings, EAV-400 could be inferred to be a possible anti-epileptic option for the treatment of epilepsy of this plan in preclinical research.

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Qu, Suqing, Weipeng Liu, Hui Yang, Zhaoyan Wang, Yinxiang Yang, Fang Liu, Aruna Sharma, Hari Sharma, and Zuo Luan. "Clinical Observation of Electroencephalographic Changes and Risk of Convulsion Occurrence in Children Receiving Neural Precursor Cell Transplantation." CNS & Neurological Disorders - Drug Targets 17, no. 3 (June 19, 2018): 233–39. http://dx.doi.org/10.2174/1871527317666180424121947.

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Purpose: This study was intended to observe electroencephalographic (EEG) changes and convulsion attacks in children receiving neural precursor cell transplantation, and to explore the possibility of electrophysiological changes and risk of convulsion occurrence after cell transplantation. Method: 228 children were included in this study who received neural precursor cell transplantation in our hospital between March 2008 and July 2012. No history of convulsion attacks was elicited before cell transplantation. Data about EEG change and convulsion occurrence before and after cell transplantation were analyzed statistically. Results: Of the 228 pediatric patients, EEG improvement, deterioration and no significant change were observed in 60, 45 and 122 patients, respectively. One month after transplantation, four (1.76%) patients experienced new convulsions. Of the 227 patients, 25 showed increased and/or abnormal discharges on EEG. Of these, 19 underwent EEG re-examination six months post-operation. Except the convulsive cases mentioned above, there were no new cases of convulsions in the remaining patients. Of the 27 patients including those with abnormal discharge, increased discharge and convulsion attacks, 17 achieved varying degrees of therapeutic efficacy. Conclusion: Intraventricular transplantation of neural precursor cells is associated with EEG changes in some children and clinical convulsion attacks in individual patients. However, these abnormal changes do not last long and usually return to normal levels within 1-6 months after surgery, along with disappearance of convulsions. Simultaneous occurrence of EEG changes and convulsions do not appear to affect therapeutic efficacy.

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Sadgunottama goud kamparaj, Kudagi B L, Karikal H P, Muthiah N S, and Pravin Kumar R. "Evaluation of the anticonvulsant activity of the phosphodiesterase III inhibitor cilostazol in the animal model of epilepsy." International Journal of Research in Pharmaceutical Sciences 11, no. 3 (July 8, 2020): 3391–95. http://dx.doi.org/10.26452/ijrps.v11i3.2476.

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The present study is objected to evaluate the anticonvulsant activity of the phosphodiesterase III inhibitor cilostazol in the animal model of epilepsy. Conventional anti-epileptic rodent models like Maximal Electric Shock (MES)- induced convulsions and Pentylenetetrazol (PTZ) induced convulsions were used. The animals were randomly divided into six groups, with six rats in every group. Here anti-epileptic activity of cilostazol with two different doses (10 mg/kg i.p and 20 mg/kg i.p) was compared with standard drug and standard drug + Cilostazol two different doses (10 mg/kg i.p and 20 mg/kg i.p). Cilostazol (20 mg/kg i.p) exhibited an anticonvulsant effect in MES-induced and PTZ induced convulsion models over the Control group and cilostazol (10 mg/kg i.p). Standard drugs were shown superiority in seizure suppression activity than cilostazol (20 mg/kg i.p). The time duration of onset of clonic convulsion and period of clonic convulsions in PTZ induced convulsion were increased and decreased respectively when compared to Standard drug + cilostazol both doses and standard drug alone. Phenytoin abolished convulsions induced by MES- convulsion model. So the present study established that cilostazol has low anticonvulsant efficacy in comparison with conventional drugs (Phenytoin and Sodium Valproate). The potentiating effect of cilostazol with standard drugs was also demonstrated.

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Sh Mahmood, Najdat, Oday Abood Khalil, and Jalil Ibrahim Alezzi. "Characteristics of Febrile Convulsions and The Association Between Ketonuria and Febrile Convulsions." Diyala Journal of Medicine 20, no. 1 (April 17, 2021): 43–49. http://dx.doi.org/10.26505/djm.20015600910.

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Background: Febrile seizures are common and mostly benign. There is growing evidence that ketone bodies derived from fatty acid oxidation during fasting or consumption of high-fat diets can exert broad neuroprotective effects, including anti-convulsant effects. Objective: To determine the characteristics of febrile convulsions and the relationship between ketonuria and febrile convulsions. Patients and Methods: A cross-sectional comparative study was done between May 2018 – December 2019 at Al-Batool teaching hospital. The data included 100 children aged between (6- 60 months) admitted to the emergency unit, 50 % of them were having a febrile convulsion, while the others were presented with fever without a seizure. Blood samples were measured for serum glucose and urine samples were taken for level of ketone bodies (KB) and analyzed by reagent strip test. Statistical analysis was done by using SPSS version 21, level of association between variables was tested by Chi-square at 0.05. Results: Febrile convulsions occur equally in males and females and more likely in children less than 18 months of age (P value=0.157). Causes of fever in children with febrile convulsion were mostly respiratory causes (p value=0. 000). The incidence of hypoglycemia and ketonuria were slightly more common in the non-convulsive group of the study to be statistically insignificant (p- values were 0.169 and 0.275, respectively). Conclusion: The febrile convulsions affect equally males and females and the major cause of fever was respiratory infections. There is no significant relationship between ketonuria and the occurrence of febrile convulsions. Keywords: Febrile convulsion; Ketonuria; Children

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BIBI, SURRIYA, MAQBOOL AHMAD, and AYESHAS AJID. "FEBRILE CONVULSIONS IN CHILDREN." Professional Medical Journal 16, no. 04 (December 10, 2009): 526–31. http://dx.doi.org/10.29309/tpmj/2009.16.04.2733.

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O b j e c t i v e s : (i) To know about the knowledge, attitude and practices of parents of children with febrile convulsions, (ii) To provideadequate information of relationship between fever and febrile convulsions and its usual good prognosis. D e s i g n : Descriptive study. S e t t i n g :It was conducted at Pediatric Department of Madina Teaching Hospital Sargodha Road Faisalabad. P e r i o d : Two years period from January2007-2009. M A T E R I A L A N D M E T H O D S : 150 parents and their children with febrile convulsions were included in the study. Diagnosis wasmade on the basis of a history of a convulsion in the child with a febrile illness. Cases were excluded when there was doubt about theoccurrence of convulsions, or if the child previously had convulsions due to any other cause, or if the physical examination or laboratoryparameters suggested any other etiology for the convulsions. LP was done in case of first time febrile fits. A pretested questionnaire comprisingof 12 questions was used for the study. Data was presented through frequency table. Statistical test of significance was Chi-square test. Thedata was analyzed with the help of SPSS computer program EQS 10 N. R e s u l t s : in the study 83 parents (59.3%) could not recognize theconvulsion; 127 parents (90.7%) did not carry out any intervention prior to getting the child to the hospital. 109 (77.9%) parents did not knowthe facts that the convulsion can occur due to fever. For 56 (40%) of the parents every subsequent episode of fever was like a nightmare. Only21 parents (15%) had thermometer at home and 28 (20%) knew the normal range of body temperature. Correct preventive measures wereknown to only 41 (29.2%). C o n c l u s i o n s : Parental fear of fever and febrile convulsion is a major problem with negative consequences affectingdaily family life. The most common immediate effect of the convulsion on the parents was fear of death and insomnia and fear of braindamage.

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Saheb, Shaik Ateal. "A study of febrile convulsions with a bacteremia incidence in a tertiary care teaching hospital in Andhra Pradesh." International Journal of Contemporary Pediatrics 7, no. 9 (August 25, 2020): 1885. http://dx.doi.org/10.18203/2349-3291.ijcp20203648.

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Background: A febrile convulsion is linked with high temperature but without significant underlying health issues. These occur most often in children aged six months to five years. Most of the convulsions last less than five minutes, and within an hour of the occurrence, the child is entirely back to normal.Methods: Sixty children aged 3 months to 5 years admitted to the emergency pediatric ward with a history of convulsion fever with convulsions, in Narayana Medical College and Hospital were taken up for the study with clinical history, clinical examination, laboratory Investigations.Results: Among 60 children in the study group, 15 (25%) of them were aged between 3 months to 12 months, 21 (35%) of them were between 13 months to 24 months. Gender 36 (60%) are male children. 24 (40%) are female children. Family history of convulsions was positive in 18 (30%) of the 60 (100%) cases, and 7 had family history of epilepsy. 42 (70%) are negative. Most of the cases (85%) showed no growth in blood culture.Conclusions: Blood culture should be performed in all children by febrile convulsions, especially those under the stage of two years. Streptococcus pneumonia was the organism isolated from respiratory tract infection in a child with febrile convulsion with significant bacteremia. The symptoms that present can be as harmless as rhinorrhea or cough. Children with a positive family history of afebrile convulsion should be closely monitored and test, as they can develop epilepsy later.

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Dissertations / Theses on the topic "Convulsions"

1

Re, Renée. "Génétique des convulsions fébriles : recensement des pédigrees et collecte des prélèvements." Montpellier 1, 1991. http://www.theses.fr/1991MON11046.

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Cordesse, Sophie. "Eléments de pronostic des méningites purulentes du nourrisson et de l'enfant : la signification des phénomènes convulsifs." Montpellier 1, 1988. http://www.theses.fr/1988MON11167.

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Doriat, Jean-François. "Adaptation fonctionnelle cérébrale et plasticité des récepteurs à la suite de convulsions expérimentales chez le rat au cours du développement." Nancy 1, 1998. http://www.theses.fr/1998NAN10353.

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Joshi, Kaushal V. "Novel Neuroprotectants for Sarin plus CBDP induced convulsions." Wright State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=wright1253321185.

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El-Hamdi, Gheziel. "Effets de convulsions induites par le pentylenetetrazole sur l'utilisation cérébrale locale de glucose et les concentrations cérébrales régionales de noradrénaline et dopamine chez le rat au cours du développement postnatal." Nancy 1, 1992. http://www.theses.fr/1992NAN12083.

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Riegle, Melissa A. "The importance of brain glycogen during acute seizure activity in mice." Muncie, IN : Ball State University, 2009. http://cardinalscholar.bsu.edu/670.

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Laurent, Corinne. "Virus herpès de type 6 et convulsions fébriles de l'enfant." Paris 5, 1997. http://www.theses.fr/1997PA05P066.

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Nabbout, Rima. "Etude phénotypique et génotypique des convulsions fébriles et des épilepsies apparentées." Paris 6, 2003. http://www.theses.fr/2003PA066108.

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Farrow, Tom F. D. "Hippocampus, cognitive function and epilepsy." Thesis, University of Sheffield, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322874.

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10

Hasni, Hedi. "Recherche sur les mécanismes biochimiques de l'action convulsivante de l'acide folique." Paris 5, 1988. http://www.theses.fr/1988PA05P613.

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Books on the topic "Convulsions"

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University of Dundee. Centre for Medical Education. Convulsions in practice. [London]: Royal College of General Practitioners, 1985.

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D, Chopra V., Misra Kashi Prasad 1929-, and International Institute for Asia Pacific Studies., eds. Asia-Pacific politico-economic convulsions. New Delhi: Continental Pub. House, 1989.

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National Institutes of Health (U.S.). Febrile seizures. Bethesda, Maryland: U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, 2012.

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Novak, Mikayla, Marta Podemska-Mikluch, and Richard E. Wagner, eds. Realism, Ideology, and the Convulsions of Democracy. Cham: Springer Nature Switzerland, 2023. http://dx.doi.org/10.1007/978-3-031-39458-4.

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Frank, Drislane, ed. Status epilepticus: A clinical perspective. Totowa, N.J: Humana Press, 2005.

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Kuturec, Marija T. Febrilni konvulzii: Predizvik za sekoj pedijatar. Skopje: Menora, 2000.

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Chʻen, Li. Effect of spinal double hemisections on amygdala-kindled convulsions. Ottawa: National Library of Canada, 1993.

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Frank, Drislane, ed. Status epilepticus: A clinical perspective. Totowa, N.J: Humana Press, 2005.

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Sudhansu, Chokroverty, ed. Management of epilepsy. Boston: Butterworth-Heinemann, 1996.

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G, Wasterlain Claude, and Treiman David M, eds. Status epilepticus: Mechanisms and management. Cambridge, Mass: MIT Press, 2006.

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Book chapters on the topic "Convulsions"

1

Bennett, Andrew, and Nicholas Royle. "Convulsions." In Elizabeth Bowen and the Dissolution of the Novel, 140–57. London: Palgrave Macmillan UK, 1995. http://dx.doi.org/10.1057/9780230374355_8.

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Borelli, Giovanni Alfonso. "On convulsions." In On the Movement of Animals, 420–21. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-73812-8_47.

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Kwon, Jennifer M. "Febrile Convulsions." In Encyclopedia of Autism Spectrum Disorders, 1. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4614-6435-8_22-3.

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Ward, Tracey, Raphael Bernier, Cora Mukerji, Danielle Perszyk, James C. McPartland, Ellen Johnson, Susan Faja, et al. "Febrile Convulsions." In Encyclopedia of Autism Spectrum Disorders, 1254. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1698-3_22.

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Kwon, Jennifer M. "Febrile Convulsions." In Encyclopedia of Autism Spectrum Disorders, 1988–89. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-91280-6_22.

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Desnick, Robert J., Orlando Guntinas-Lichius, George W. Padberg, Gustav Schonfeld, Xiaobo Lin, Maurizio Averna, Pin Yue, et al. "Febrile Convulsions." In Encyclopedia of Molecular Mechanisms of Disease, 647. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_7532.

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Gartler, Stanley M., R. Scott Hansen, Vinzenz Oji, Heiko Traupe, Julia Horn, Bodo Grimbacher, Srijita Sen-Chowdhry, et al. "Infantile Convulsions." In Encyclopedia of Molecular Mechanisms of Disease, 1047. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_9247.

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Froehlich, Stephan J., Carlo A. Lackerbauer, Guenter Rudolph, Jan Rémi, Soheyl Noachtar, Werner J. Heppt, Annette Cryer, et al. "Neonatal Convulsions." In Encyclopedia of Molecular Mechanisms of Disease, 1440–41. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_9284.

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Fry, John. "Epilepsy and Convulsions." In Common Diseases, 319–26. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-4924-9_42.

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Froehlich, Stephan J., Carlo A. Lackerbauer, Guenter Rudolph, Jan Rémi, Soheyl Noachtar, Werner J. Heppt, Annette Cryer, et al. "Neonatal-infantile Convulsions." In Encyclopedia of Molecular Mechanisms of Disease, 1441. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_9286.

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Conference papers on the topic "Convulsions"

1

Zhang, Dandan, Haiyan Ding, Datian Ye, Xinlin Hou, Yunfeng Liu, and Congle Zhou. "Burst Suppression EEG in Neonatal Convulsions." In 2010 International Conference on Biomedical Engineering and Computer Science (ICBECS). IEEE, 2010. http://dx.doi.org/10.1109/icbecs.2010.5462478.

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Chatterton Dickson, L., and J. Shetty. "G319(P) Outcomes following febrile convulsions: a retrospective cohort study." In Royal College of Paediatrics and Child Health, Abstracts of the Annual Conference, 13–15 March 2018, SEC, Glasgow, Children First – Ethics, Morality and Advocacy in Childhood, The Journal of the Royal College of Paediatrics and Child Health. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2018. http://dx.doi.org/10.1136/archdischild-2018-rcpch.309.

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Tsukimata, Márcio Yutaka, Bianca Lumi Inomata da Silva, and Jennison Alves Guimarães. "Açaí: potential anticonvulsant agent." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.064.

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Background: Convulsion is an involuntary contraction of skeletal muscles. When considering vulnerable populations exposed to the mentioned pathophysiological situation, it is recognized that many of them will not have access to the indicated pharmacological treatment. Therefore, the ingestion of açai, Euterpe oleracea (EO) attenuates the problem, acting as an anticonvulsant. Objectives: evaluate the EO as an anticonvulsant agent. Design and setting: It is a bibliographic research and the data collection was done from the PubMed and Scielo databases. Methods: The descriptor used was “Euterpe oleracea” and the inclusion criteria adopted were: articles published in the last five years, available in full and publications related to epilepsy. Results: The EO acts on the GABAergic system when interacting occurs with the GABA receptor of cortical neurons and, above all, of astrocytes in an inhibitory mechanism for the uptake of the neurotransmitter GABA, that accumulates in the synaptic cleft, preventing the exaggerated neurotransmission that causes convulsions. In pentylenetetrazol-induced seizure (PTZ), EO showed some results similar to diazepam: reduced duration of tonic-clonic convulsion and increased latencies for the first myoclonic spasm and for the first generalized tonic-clonic seizure. Conclusions: Studies suggest that EO can be classified as an anticonvulsant, considering its inhibitory activity during synapses. Furthermore, the consumption of EO is more viable at a socioeconomic level compared to traditional drug treatments.

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4

Kukuruzovic, Monika. "391 Febrile convulsions and influenza A or B- are there differences?" In 10th Europaediatrics Congress, Zagreb, Croatia, 7–9 October 2021. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2021. http://dx.doi.org/10.1136/archdischild-2021-europaediatrics.391.

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5

Milosevic, Milica, Anouk Van de Vel, Bert Bonroy, Berten Ceulemans, Lieven Lagae, Bart Vanrumste, and Sabine Van Huffel. "Detection of epileptic convulsions from accelerometry signals through machine learning approach." In 2014 IEEE 24th International Workshop on Machine Learning for Signal Processing (MLSP). IEEE, 2014. http://dx.doi.org/10.1109/mlsp.2014.6958863.

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6

Akhuemokhan, OC, J. Ehiemua, DI Adomeh, I. Odia, SC Olomu, B. Becker-Ziaja, CT Happi, et al. "G311 Lassa fever and convulsions associated with fever: A case-control study." In Royal College of Paediatrics and Child Health, Abstracts of the Annual Conference, 24–26 May 2017, ICC, Birmingham. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2017. http://dx.doi.org/10.1136/archdischild-2017-313087.304.

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7

Bela Klancir, S., I. Mrkić Kobal, G. Krakar, F. Sabol, M. Kovač Šižgorić, G. Tešović, M. Meštrović, et al. "488 Can benign afebrile convulsions associated with mild gastroenteritis be prevented by vaccination?" In 10th Europaediatrics Congress, Zagreb, Croatia, 7–9 October 2021. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2021. http://dx.doi.org/10.1136/archdischild-2021-europaediatrics.488.

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8

Klancir, Svjetlana Bela, I. Mrkić Kobal, G. Krakar, F. Sabol, Kovač Šižgorić, G. Tešović, M. Meštrović, et al. "492 Can benign afebrile convulsions associated with mild gastroenteritis be prevented by vaccination?" In 10th Europaediatrics Congress, Zagreb, Croatia, 7–9 October 2021. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2021. http://dx.doi.org/10.1136/archdischild-2021-europaediatrics.492.

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9

Makarov, A. F., and V. Yu Tkachuk. "ARTIFICIAL HYPOBIOSIS AS METHOD OF ACUTE ALTITUDE ILLNESS NEGATIVE IMPACT REDUCTION." In The 4th «OCCUPATION and HEALTH» International Youth Forum (OHIYF-2022). FSBSI «IRIOH», 2022. http://dx.doi.org/10.31089/978-5-6042929-6-9-2022-1-152-155.

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Introduction: While reaching ever new heights mankind met an altitude illness. A critical stage of altitude sickness, manifesting by loss of consciousness, convulsions, apnea and subsequent death, develops at above 7 km altitudes. Pilots, alpinists and extreme sportsmen are the main risk group. Acute oxygen starvation of body while significant hypobaric hypoxia is the main mechanism of altitude illness. It is proposed to reduce the level of metabolism (artificial hypobiosis) to prevent the negative impact of acute hypobaric hypoxia. The study goal to assess the efficiency of organism negative impact prevention with metabolic rate reduction while acute hypobaric hypoxia. Materials and methods: Syrian hamsters, 90–110 g weight were used in the study. 2 groups, 8 animals in each. Experimental group of animals had intramuscular injections of 1 ml 0.9% NaCl containing 1 g/kg Methyldop (CAS Number 555-30-6) in 0.3 ml/kg dimethyl sulfoxide (DMSO) suspension. Control group of animals had 1 ml 0.9% NaCl containing 0.3 ml/kg DMSO. 3 hours later animals had been placed in hypobaric chamber. 20 kPa under pressure was created, speed – 1.25 kPa/s. Continuous chamber air flow was made to avoid CO2 accumulation. Continuous visual observation carried out. Consciousness, posture maintenance time, convulsive seizures, agonal breathing, and apnea were registered. Results: Control group: since start of exposure the average animal posture maintenance time was 3 s (standard error (SE) – 4 s). First convulsion time – 20 s (SE – 8 s), second convulsion – 56 s (SE – 14 s), agonal breath type start (6 animals) – 52 s (SE – 20 s), apnea – 1 min 54 s (SE – 1 min 8 s). It was consciousness absence in all animal. Experimental group: none of registered parameters were observed. All animals had consciousness, actively restored their position, while chamber was tilted. The exposure lasted for 20 minutes. Conclusions: Metabolic rate reduction has high efficiency for organism negative impact prevention while acute hypobaric hypoxia.

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PINHEIRO, T. F. M., J. C. LEMOS, M. M. BEZERRA, L. M. V. AGUIAR, and G. C. FILHO. "SCNS. 12. Effects of trimetazidine on pilocarpine-induced convulsions in mice: behavioral changes and glutamatergic system modulation." In I International Symposium in Neuroscience Meeting. Editora Edgard Blücher, 2014. http://dx.doi.org/10.5151/isnm-sine17.

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Reports on the topic "Convulsions"

1

Peterson, Steven. Treatment Strategies fir the NMDA Component of Organophosphorous Convulsions. Fort Belvoir, VA: Defense Technical Information Center, April 2005. http://dx.doi.org/10.21236/ada435100.

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2

Peterson, Steven L., and James Griffith. Treatment Strategies for the NMDA Component of Organophosphorus Convulsions. Fort Belvoir, VA: Defense Technical Information Center, September 2002. http://dx.doi.org/10.21236/ada412570.

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3

Peterson, Steven L., and James Griffith. Treatment Strategies for the NMDA Component of Organophosphorus Convulsions. Fort Belvoir, VA: Defense Technical Information Center, September 2003. http://dx.doi.org/10.21236/ada418693.

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4

Guo, Jia, Xibin Hu, Lei Yao, Shaomin Lv, Jiahua Lv, Xinyu Wang, Mujie Guo, Yu Kong, Ruihan Liu, and Qingxia Kong. Prognosis After Surgery for Refractory Epilepsy Diagnosed by 18F-FDG PET/MRI. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0049.

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Review question / Objective: The purpose of this study was to examine the prognostic status of PET/MRI on surgery in patients with refractory epilepsy, and the methods chosen were randomized controlled trials, cohort studies, and case series of >15 patients. Condition being studied: Medically intractable epilepsy, characterized by recurrent episodes of tonicity, disorientation, spasms, and convulsions, affects 1-2% of the population because treatment trials with 3 or more different antiepileptic drugs have failed. Patients are selected for PET mainly because other standard noninvasive tests (especially MRI and EEG) fail to provide sufficiently reliable localization to allow precise excision of the epileptogenic zone and a good prognosis.

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Wang, Xiaoyu. Pediatric TuiNa for Tourette syndrome in children: A systematic review and meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2023. http://dx.doi.org/10.37766/inplasy2023.4.0077.

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Review question / Objective: Efficacy and Safety of Pediatric TuiNa for Tourette Syndrome: A Systematic Review and Meta-Analysis of randomized controlled trials. Condition being studied: Tourette syndrome (TS) is a common psychological, behavioural and neuropsychiatric disorder characterized by chronic, fluctuating, multiple muscle convulsions, or accompanied by involuntary laryngeal abnormalities and indecent language. It mainly appears in childhood. At present, Tourette syndrome generally has a long course of the disease and is difficult to cure, which seriously affects the children's learning and physical and mental health, and also causes panic and anxiety to many parents. The incidence of Tourette syndrome was increasing year by year. Clinical studies found that only relying on Western medicine for treatment was easy to have recurrent symptoms and serious adverse reactions. Traditional Chinese medicine has great advantages in the treatment of Tourette syndrome, especially in children's massage, because it has no side effects and is more likely to be favoured by parents. To provide a better basis and guidance for clinical treatment by Meta-analysis of the literature on tuina treatment of Tourette syndrome in children.

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Valencia Ríos, Dahian David, Andrea Carolina Ibáñez Acosta, and Yamile Calle López. Manejo de la mujer gestante con epilepsia: Secretos que todo médico debería saber. Facultad de Medicina Universidad de Antioquia, September 2023. http://dx.doi.org/10.59473/medudea.pc.2023.40.

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El 33,4 % de las mujeres con epilepsia padecen crisis convulsivas durante la gestación (3). En cuanto a la frecuencia ictal, será en términos generales la misma del año previo a la concepción, con un aumento en el 15 % de gestaciones, sin cambios en el 70,5 %, y reducción en el 12 % (EURAP, European Registry of Antiepileptic Drugs and Pregnancy, por sus siglas en inglés).

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A, Bengolea, and Izcovich A. Anticomiciales profilácticos en masa ocupante de sistema nervioso central o post operatorio de neurocirugía. Epistemonikos Interactive Evidence Synthesis, December 2023. http://dx.doi.org/10.30846/ies.45cad38d17.

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Objetivo El objetivo de esta revisión sistemática es evaluar el efecto profiláctico de los anticomiciales en de pacientes con masa ocupantes del sistema nervioso central (SNC) o post operatorio de neurocirugía de SNC. Métodos Este manuscrito fue desarrollado siguiendo las directrices de las guías ‘Preferred Reporting Items for Systematic reviews and Meta-Analyses’ (PRISMA) para el reporte de revisiones sistemática y metaanálisis.[ ff901d67951ef9bc45b3e805c2223277f0efcac3 Criterios de selección En esta revisión sistemática, se incluyeron ensayos clínicos aleatorizados que evaluaron el efecto del uso de Anticomiciales profilacticos en Pacientes con masa ocupantes de SNC. Los desenlaces de interés considerados en esta revisión fueron: Mortalidad Crisis convulsiva Búsqueda de literatura Búsqueda electrónica Conclusiones El uso de anticomiciales profilácticos podría resultar en una pequeña reducción en la mortalidad. El uso de anticomiciales profilácticos podría resultar en una pequeña reducción en los eventos de crisis convulsivas.

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A, Bengolea, and Izcovich A. Anticomiciales profilácticos en masa ocupante de sistema nervioso central o post operatorio de neurocirugía. Epistemonikos Interactive Evidence Synthesis, December 2023. http://dx.doi.org/10.30846/ies.45cad38d17.v1.

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Objetivo El objetivo de esta revisión sistemática es evaluar el efecto profiláctico de los anticomiciales en de pacientes con masa ocupantes del sistema nervioso central (SNC) o post operatorio de neurocirugía de SNC. Métodos Este manuscrito fue desarrollado siguiendo las directrices de las guías ‘Preferred Reporting Items for Systematic reviews and Meta-Analyses’ (PRISMA) para el reporte de revisiones sistemática y metaanálisis.[ ff901d67951ef9bc45b3e805c2223277f0efcac3 Criterios de selección En esta revisión sistemática, se incluyeron ensayos clínicos aleatorizados que evaluaron el efecto del uso de Anticomiciales profilacticos en Pacientes con masa ocupantes de SNC. Los desenlaces de interés considerados en esta revisión fueron: Mortalidad Crisis convulsiva Búsqueda de literatura Búsqueda electrónica Conclusiones El uso de anticomiciales profilácticos podría resultar en una pequeña reducción en la mortalidad. El uso de anticomiciales profilácticos podría resultar en una pequeña reducción en los eventos de crisis convulsivas.

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9

Prescribing regular drugs to prevent febrile convulsions risks more harm than benefit. National Institute for Health Research, August 2017. http://dx.doi.org/10.3310/signal-000456.

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