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1

Fisher, Margaret C. Immunizations & infectious diseases: An informed parent's guide. Edited by Fisher Margaret C and American Academy of Pediatrics. Washington, D.C: American Academy of Pediatrics, 2006.

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2

K, Pickering Larry, ed. 2000 Red book: Report of the Committee on Infectious Diseases. 2nd ed. Elk Grove Village, IL: American Academy of Pediatrics, 2000.

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3

American Academy of Pediatrics Committee on Infectious Diseases. Red book: 2003 report of the Committee on Infectious Diseases. 2nd ed. Washington, D.C: American Academy of Pediatrics, 2003.

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4

Office, General Accounting. Immunization: HHS could do more to increase vaccination among older adults : report to Congressional requesters. Washington, D.C: The Office, 1995.

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5

Office, General Accounting. Global health: Summary of conference on immunization in developing countries : report to congressional requesters. Washington, D.C. (P.O. Box 37050, Washington, D.C. 20013): The Office, 2000.

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6

Office, General Accounting. Global health: Challenges in improving infectious disease surveillance systems : report to Congressional requesters. Washington, D.C: The Office, 2001.

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7

Office, General Accounting. Global health: U.S. Agency for International Development fights AIDS in Africa, but better data needed to measure impact : report to the Chairman, Subcommittee on African Affairs, Committee on Foreign Relations, U.S. Senate. Washington, D.C: The Office, 2001.

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8

Burchell, Ann, and Eduardo Franco1. The impact of immunization on cancer control: the example of HPV vaccination. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199550173.003.0006.

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Chapter 6 reviews briefly the role of infections as causal agents in cancer, describes anti-hepatitis B virus (HBV) immunization as the first cancer vaccine paradigm, and finally focuses on the latest paradigm of prophylactic vaccination against human papillomavirus (HPV) infection as the new front in cancer prevention.
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9

Van Buynder, Paul, and Elizabeth Brodkin. Healthcare worker screening for nosocomial pathogens. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0284.

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Health care organizations and their staff have a responsibility to prevent occupationally-acquired infections and avoid transmitting disease to patients. As well as being a known source of nosocomial infections, health care workers (HCWs) are at risk themselves of becoming infected in the workplace. Regulatory authorities in many countries advise or mandate screening for key blood-borne pathogens (BBPs) in settings where transmission between patients and staff is possible. Staff infected with a BBP are restricted from performing certain procedures. In addition to screening for BBP, health care organizations require a tuberculosis infection control programme. Routine screening of health care workers for other organisms such as MRSA is usually not indicated. Health care organizations should have robust policies to immunize health care workers against Hepatitis B and respiratory diseases. Many organizations now make immunization against key respiratory diseases a pre-requisite for employment as a key infection control patient safety strategy.
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10

Devlin, Hugh, and Rebecca Craven. Immune system. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198759782.003.0011.

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The immune system in relation to dentistry is the topic of this chapter. Non-specific body defences are explored. Then follows specific body defences, humoral and cell mediated responses; antibody types and their mechanisms of action and the clinical application in immunization. Inflammation, both acute and chronic, is explored in relation to infections of dental origin and their complications. Problems with the immune system and hypersensitivity follow. Normal oral flora and dental plaque and the body’s response in periodontal inflammation are explored. The final section deals with the implications of what has gone before for infection control in the dental surgery.
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11

Britain), Stationery Office (Great. Immunization Against Infectious Disease. Bernan Press, 1992.

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12

Fox, Grenville, Nicholas Hoque, and Timothy Watts. Infection. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198703952.003.0012.

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This chapter provides a problem-oriented approach to investigation and treatment of early and late onset neonatal bacterial infection, including group B streptococcus, meningitis, urine infection, conjunctivitis, umbilical sepsis, osteomyelitis, and septic arthritis. In addition, the prevention and management of congenital infection is covered, including hepatitis B and C, HIV, syphilis, CMV, toxoplasma, rubella, herpes simplex, and chickenpox. Other topics covered are infection control (including MRSA), fungal sepsis, TB, and an overview of immunizations in the first year of life.
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13

Baxter, David, Sam Ghebrehewet, and Gill Marsh. Immunization. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198745471.003.0019.

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Immunization has been used by human societies for more than a thousand years to control a number of important vaccine-preventable infections. Currently an infant born in an industrialized society will be immunized against more than 25 pathogens by 13 months of age; an elderly person in the same country will similarly be offered protection against 28 pathogens. The main reasons for continuing with immunization programmes in the face of declining rates of vaccine-preventable diseases/infections are discussed. This chapter also looks at the different vaccines that are widely used in many countries, describing the four main types and explaining how they utilize the body’s natural defence systems to provide protection. Vaccines are the most complex agents used by healthcare workers and this chapter reviews their different components and explains their different functions.
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14

N, Di Lima Sara, Eutsey Dwayne E, and Aspen Reference Group (Aspen Publishers), eds. Infectious disease resource manual. Gaithersburg, Md: Aspen Publishers, 1999.

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15

Alexander, D. J., N. Phin, and M. Zuckerman. Influenza. Edited by I. H. Brown. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0037.

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Influenza is a highly infectious, acute illness which has affected humans and animals since ancient times. Influenza viruses form the Orthomyxoviridae family and are grouped into types A, B, and C on the basis of the antigenic nature of the internal nucleocapsid or the matrix protein. Infl uenza A viruses infect a large variety of animal species, including humans, pigs, horses, sea mammals, and birds, occasionally producing devastating pandemics in humans, such as in 1918 when it has been estimated that between 50–100 million deaths occurred worldwide.There are two important viral surface glycoproteins, the haemagglutinin (HA) and neuraminidase (NA). The HA binds to sialic acid receptors on the membrane of host cells and is the primary antigen against which a host’s antibody response is targeted. The NA cleaves the sialic acid bond attaching new viral particles to the cell membrane of host cells allowing their release. The NA is also the target of the neuraminidase inhibitor class of antiviral agents that include oseltamivir and zanamivir and newer agents such as peramivir. Both these glycoproteins are important antigens for inducing protective immunity in the host and therefore show the greatest variation.Influenza A viruses are classified into 16 antigenically distinct HA (H1–16) and 9 NA subtypes (N1–9). Although viruses of relatively few subtype combinations have been isolated from mammalian species, all subtypes, in most combinations, have been isolated from birds. Each virus possesses one HA and one NA subtype.Last century, the sudden emergence of antigenically different strains in humans, termed antigenic shift, occurred on three occasions, 1918 (H1N1), 1957 (H2N2) and 1968 (H3N2), resulting in pandemics. The frequent epidemics that occur between the pandemics are as a result of gradual antigenic change in the prevalent virus, termed antigenic drift. Epidemics throughout the world occur in the human population due to infection with influenza A viruses, such as H1N1 and H3N2 subtypes, or with influenza B virus. Phylogenetic studies have led to the suggestion that aquatic birds that show no signs of disease could be the source of many influenza A viruses in other species. The 1918 H1N1 pandemic strain is thought to have arisen as a result of spontaneous mutations within an avian H1N1 virus. However, most pandemic strains, such as the 1957 H2N2, 1968 H3N2 and 2009 pandemic H1N1, are considered to have emerged by genetic re-assortment of the segmented RNA genome of the virus, with the avian and human influenza A viruses infecting the same host.Influenza viruses do not pass readily between humans and birds but transmission between humans and other animals has been demonstrated. This has led to the suggestion that the proposed reassortment of human and avian influenza viruses takes place in an intermediate animal with subsequent infection of the human population. Pigs have been considered the leading contender for the role of intermediary because they may serve as hosts for productive infections of both avian and human viruses, and there is good evidence that they have been involved in interspecies transmission of influenza viruses; particularly the spread of H1N1 viruses to humans. Apart from public health measures related to the rapid identification of cases and isolation. The main control measures for influenza virus infections in human populations involves immunization and antiviral prophylaxis or treatment.
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16

Vaccines 86: New approaches to immunization : developing vaccines against parasitic, bacterial, and viral diseases. Cold Spring Harbor, N.Y: Cold Spring Harbor Laboratory, 1986.

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17

Red Book 2009 Report Of The Committee On Infectious Diseases. American Academy of Pediatrics, 2009.

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18

(Editor), Richard A. Lerner, ed. Vaccines 86: New Approaches to Immunization : Developing Vaccines Against Parasitic, Bacterial, and Viral Diseases (Vaccines) (Vaccines). Cold Spring Harbor Laboratory Pr, 1986.

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19

Sahn, David E. Is Food the Answer to Malnutrition? Edited by Ronald J. Herring. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780195397772.013.030.

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Although there is little disagreement on the magnitude and importance of alleviating malnutrition, its causation and control continue to be the subject of debate and research. Recent evidence suggests that many of the traditional food-based strategies to reduce malnutrition, such as food aid distribution programs, school feeding programs, and food stamps, as well as policies that intervene to affect the price of food such as subsidies and rationing schemes, have proven of limited effectiveness. One important reason is that the critical period of undernutrition is generally in utero and early life. Among the most vulnerable groups, particularly pregnant women and infants, the causes of malnutrition often have little to do with food access and availability. Instead, prenatal care, immunization programs, breastfeeding promotion, and generally raising the quality of child care and nurturing behaviors are paramount. Likewise, improving the sanitary and home environment, including interventions that enhance access to clean water and latrines and behaviors such as hand washing and boiling water, will contribute to reductions in infection and help break the cycle of disease and malnutrition. In the area of food-related interventions, among those that are critical to the production of improved health and nutritional outcomes are food supplementation and fortification schemes that address micronutrient deficiencies. At the same time, there is legitimate concern that misguided food interventions, particularly broad-based price subsidies, food stamps, and food aid may have a range of deleterious consequences. These range from contributing to the epidemic of obesity and related chronic disease, to having a negative impact on farmers and producer incentives and the functioning of food markets.
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20

Pediatrics, American Academy of, and Committee on Infectious Diseases. 2000 Red Book: Report of the Committee on Infectious Diseases. 2nd ed. American Academy of Pediatrics, 2000.

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21

Levy, David. Some practical matters. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198766452.003.0012.

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Type 1 diabetes in older people can be challenging; food and insulin are taken less reliably, and some have cognitive impairment. Simplify insulin regimens where appropriate; ‘low’ A1C measurements may signify recurrent hypoglycaemia. The regulatory framework for drivers in Europe is less tolerant of serious hypoglycaemia. Intensive education is required and precautions while driving need reinforcing. Severe hypoglycaemia in the young is associated with impaired school performance, especially in verbal IQ and spelling. Educational attainment is not affected by Type 1 diabetes, but there is some evidence for poor progression in employment, especially in women. Though popular, the evidence supporting structured education in Type 1 diabetes is weak. Peer support using social media is increasing; evidence for benefit is lacking. Serious bacterial infections are probably more common. Ensure all Type 1 patients are up to date with immunizations. Periodontal infections, common and sometimes severe, are reciprocally related to glycaemic control.
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22

Immunization: HHS could do more to increase vaccination among older adults : report to Congressional requesters. Washington, D.C. (P.O. Box 37050, Washington 20013): The Office, 1995.

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23

Pediatrics, American Academy of, and Committee on Infectious Diseases. Red Book 2006: Report of the Committee on Infectious Diseases (Red Book: Report/ Comm/ Infectious Disease). 2nd ed. American Academy of Pediatrics, 2006.

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24

S, Keystone J., ed. Travel medicine. New York: Elsevier Ltd., 2004.

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25

David, Freedman, Jay Keystone, Phyllis Kozarsky, and Hans Nothdurft. Travel Medicine. Mosby, 2003.

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26

(Editor), Stacey Knobler, Joshua Lederberg (Editor), and Leslie A. Pray (Editor), eds. Considerations for Viral Disease Eradication: Lessons Learned and Future Strategies: Workshop Summary. National Academies Press, 2002.

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27

Office, General Accounting. Global health: Factors contributing to low vaccination rates in developing countries : report to Congressional requesters. Washington, D.C. (P.O. Box 37050, Washington, D.C. 20013): The Office, 1999.

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28

Office, General Accounting. Global health: U.S. Agency for International Development fights AIDS in Africa, but better data needed to measure impact : report to the Chairman, Subcommittee on African Affairs, Committee on Foreign Relations, U.S. Senate. Washington, D.C: The Office, 2001.

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29

Office, General Accounting. Global health: U.S. Agency for International Development fights AIDS in Africa, but better data needed to measure impact : report to the Chairman, Subcommittee on African Affairs, Committee on Foreign Relations, U.S. Senate. Washington, D.C: The Office, 2001.

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30

Global health: Factors contributing to low vaccination rates in developing countries : report to congressional requesters. Washington, D.C: The Office, 1999.

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31

Office, General Accounting. Global health: Joint U.N. Programme on HIV/AIDS needs to strengthen country- level efforts and measure results : report to the chairman, Subcommittee on African Affairs, Committee on Foreign Relations, U.S. Senate. Washington, D.C: The Office, 2001.

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32

Office, General Accounting. Global health: Joint U.N. Programme on HIV/AIDS needs to strengthen country- level efforts and measure results : report to the chairman, Subcommittee on African Affairs, Committee on Foreign Relations, U.S. Senate. Washington, D.C: The Office, 2001.

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33

Office, General Accounting. Global health: U.S. Agency for International Development fights AIDS in Africa, but better data needed to measure impact : report to the Chairman, Subcommittee on African Affairs, Committee on Foreign Relations, U.S. Senate. Washington, D.C: The Office, 2001.

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34

Office, General Accounting. Global health: U.S. Agency for International Development fights AIDS in Africa, but better data needed to measure impact : report to the Chairman, Subcommittee on African Affairs, Committee on Foreign Relations, U.S. Senate. Washington, D.C: The Office, 2001.

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35

Office, General Accounting. Global health: Factors contributing to low vaccination rates in developing countries : report to congressional requesters. Washington, D.C: The Office, 1999.

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36

Office, General Accounting. Global health: U.S. Agency for International Development fights AIDS in Africa, but better data needed to measure impact : report to the Chairman, Subcommittee on African Affairs, Committee on Foreign Relations, U.S. Senate. Washington, D.C: The Office, 2001.

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