Academic literature on the topic 'Computational Molecular Biology'
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Journal articles on the topic "Computational Molecular Biology"
Wong, Wing Hung. "Computational Molecular Biology." Journal of the American Statistical Association 95, no. 449 (March 2000): 322–26. http://dx.doi.org/10.1080/01621459.2000.10473934.
Full textSadiku, Matthew N. O., Yonghui Wang, Suxia Cui, and Sarhan M. Musa. "COMPUTATIONAL BIOLOGY." International Journal of Advanced Research in Computer Science and Software Engineering 8, no. 6 (June 30, 2018): 66. http://dx.doi.org/10.23956/ijarcsse.v8i6.616.
Full textLloyd, A. "Computational Methods in Molecular Biology." Briefings in Bioinformatics 1, no. 3 (January 1, 2000): 315–16. http://dx.doi.org/10.1093/bib/1.3.315.
Full textMartin, D. "Computational Molecular Biology: An Introduction." Briefings in Bioinformatics 2, no. 2 (January 1, 2001): 204–6. http://dx.doi.org/10.1093/bib/2.2.204.
Full textBrutlag, Douglas L. "Genomics and computational molecular biology." Current Opinion in Microbiology 1, no. 3 (June 1998): 340–45. http://dx.doi.org/10.1016/s1369-5274(98)80039-8.
Full textHunter, Lawrence. "Progress in computational molecular biology." ACM SIGBIO Newsletter 19, no. 3 (December 1999): 9–12. http://dx.doi.org/10.1145/340358.340374.
Full textRay, L. B., L. D. Chong, and N. R. Gough. "Computational Biology." Science Signaling 2002, no. 148 (September 3, 2002): eg10-eg10. http://dx.doi.org/10.1126/stke.2002.148.eg10.
Full textSarpeshkar, R. "Analog synthetic biology." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 372, no. 2012 (March 28, 2014): 20130110. http://dx.doi.org/10.1098/rsta.2013.0110.
Full textCasadio, Rita, Boris Lenhard, and Michael J. E. Sternberg. "Computational Resources for Molecular Biology 2021." Journal of Molecular Biology 433, no. 11 (May 2021): 166962. http://dx.doi.org/10.1016/j.jmb.2021.166962.
Full textGentleman, Robert. "Current Topics in Computational Molecular Biology." Journal of the American Statistical Association 99, no. 466 (June 2004): 560. http://dx.doi.org/10.1198/jasa.2004.s328.
Full textDissertations / Theses on the topic "Computational Molecular Biology"
Istrail, Sorin. "Computational molecular biology /." Amsterdam [u.a.] : Elsevier, 2003. http://www.loc.gov/catdir/toc/fy037/2003051360.html.
Full textVialette, Stéphane. "Algorithmic Contributions to Computational Molecular Biology." Habilitation à diriger des recherches, Université Paris-Est, 2010. http://tel.archives-ouvertes.fr/tel-00862069.
Full textPettersson, Fredrik. "A multivariate approach to computational molecular biology." Doctoral thesis, Umeå : Univ, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-609.
Full textDinescu, Adriana. "Metals in Chemistry and Biology: Computational Chemistry Studies." Thesis, University of North Texas, 2007. https://digital.library.unt.edu/ark:/67531/metadc3678/.
Full textKarathia, Hiren Mahendrabhai. "Development and application of computational methdologies for Integrated Molecular Systems Biology." Doctoral thesis, Universitat de Lleida, 2012. http://hdl.handle.net/10803/110518.
Full textEl objetivo del trabajo presentado en esta tesis fue el desarrollo y la aplicación de metodologías computacionales que integran el análisis de la secuencia y de la información funcional y genómica, con el objetivo de reconstruir, anotar y organizar proteomas completos, de tal manera que estos proteomas se puedan comparar entre cualquier número de organismos con genomas completamente secuenciados. Metodológicamente, I centrado en la identificación de organización molecular dentro de un proteoma completo de un organismo de referencia, vinculando cada proteína en que proteoma a las proteínas de otros organismos, de tal manera que cualquiera puede comparar los dos proteomas en espacial, estructural, funcional tejido, celular, el desarrollo o los niveles de la fisiología. La metodología se aplicó para abordar la cuestión de la identificación de organismos modelo adecuados para estudiar diferentes fenómenos biológicos. Esto se hizo comparando conjuntos de proteínas involucradas en diferentes fenómenos biológicos en Saccharomyces cerevisiae y Homo sapiens con los conjuntos correspondientes de otros organismos con genomas completamente secuenciados. La tesis concluye con la presentación de un servidor web, Homol-MetReS, en el que se implementa la metodología. Homol-MetReS proporciona un entorno de código abierto a la comunidad científica en la que se pueden realizar múltiples niveles de comparación y análisis de proteomas.
The aim of the work presented in this thesis was the development and application of computational methodologies that integrate sequence, functional, and genomic information to provide tools for the reconstruction, annotation and organization of complete proteomes in such a way that the results can be compared between any number of organisms with fully sequenced genomes. Methodologically, I focused on identifying molecular organization within a complete proteome of a reference organism and comparing with proteomes of other organisms at spatial, structural, functional, cellular tissue, development or physiology levels. The methodology was applied to address the issue of identifying appropriate model organisms to study different biological phenomena. This was done by comparing the protein sets involved in different biological phenomena in Saccharomyces cerevisiae and Homo sapiens. This thesis concludes by presenting a web server, Homol-MetReS, on which the methodology is implemented. It provides an open source environment to the scientific community on which they can perform multi-level comparison and analysis of proteomes.
Donaldson, Eric F. Baric Ralph S. "Computational and molecular biology approaches to viral replication and pathogenesis." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2008. http://dc.lib.unc.edu/u?/etd,1731.
Full textTitle from electronic title page (viewed Sep. 16, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Microbiology and Immunology Virology." Discipline: Microbiology and Immunology; Department/School: Medicine.
Cao, Dan. "Computational and experimental analysis of mRNA degradationin Saccharomyces cerevisiae." Diss., The University of Arizona, 2002. http://hdl.handle.net/10150/280160.
Full textWeis, Michael Christian. "Computational Models of the Mammalian Cell Cycle." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1323278159.
Full textEnsterö, Mats. "The multi-faceted RNA molecule : Characterization and Function in the regulation of Gene Expression." Doctoral thesis, Stockholm University, Department of Molecular Biology and Functional Genomics, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-7729.
Full textIn this thesis I have studied the RNA molecule and its function and characteristics in the regulation of gene expression. I have focused on two events that are important for the regulation of the transcriptome: Translational regulation through micro RNAs; and RNA editing through adenosine deaminations.
Micro RNAs (miRNAs) are ~22 nucleotides long RNA molecules that by semi complementarity bind to untranslated regions of a target messenger RNA (mRNA). The interaction manifests through an RNA/protein complex and act mainly by repressing translation of the target mRNA. I have shown that a pre-cursor miRNA molecule have significantly different information content of sequential composition of the two arms of the pre-cursor hairpin. I have also shown that sequential composition differs between species.
Selective adenosine to inosine (A-to-I) RNA editing is a post-transcriptional process whereby highly specific adenosines in a (pre-)messenger transcript are deaminated to inosines. The deamination is carried out by the ADAR family of proteins and require a specific sequential and structural landscape for target recognition. Only a handful of messenger substrates have been found to be site selectively edited in mammals. Still, most of these editing events have an impact on neurotransmission in the brain.
In order to find novel substrates for A-to-I editing, an experimental setup was made to extract RNA targets of the ADAR2 enzyme. In concert with this experimental approach, I have constructed a computational screen to predict specific positions prone to A-to-I editing.
Further, I have analyzed editing in the mouse brain at four different developmental stages by 454 amplicon sequencing. With high resolution, I present data supporting a general developmental regulation of A-to-I editing. I also present data of coupled editing events on single RNA transcripts suggesting an A-to-I editing mechanism that involve ADAR dimers to act in concert. A different editing pattern is seen for the serotonin receptor 5-ht2c.
Zwolak, Jason Walter. "Computational Tools for Molecular Networks in Biological Systems." Diss., Virginia Tech, 2004. http://hdl.handle.net/10919/30274.
Full textPh. D.
Books on the topic "Computational Molecular Biology"
1949-, Leszczynski Jerzy, ed. Computational molecular biology. Amsterdam: Elsevier, 1999.
Find full text1960-, Salzberg Steven L., Searls David B, and Kasif Simon, eds. Computational methods in molecular biology. Amsterdam: Elsevier, 1998.
Find full textSrinivas, Aluru, ed. Handbook of computational molecular biology. Boca Raton, FL: Chapman & Hall/CRC, 2005.
Find full textJoão, Meidanis, ed. Introduction to computational molecular biology. Boston: PWS Pub., 1997.
Find full textPe'er, Itsik, ed. Research in Computational Molecular Biology. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-04749-7.
Full textSingh, Mona, ed. Research in Computational Molecular Biology. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-31957-5.
Full textChor, Benny, ed. Research in Computational Molecular Biology. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-29627-7.
Full textBatzoglou, Serafim, ed. Research in Computational Molecular Biology. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-02008-7.
Full textBerger, Bonnie, ed. Research in Computational Molecular Biology. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-12683-3.
Full textSpeed, Terry, and Haiyan Huang, eds. Research in Computational Molecular Biology. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71681-5.
Full textBook chapters on the topic "Computational Molecular Biology"
Boukerche, Azzedine, and Alba Cristina Magalhães Alves de Melo. "Computational Molecular Biology." In Parallel Computing for Bioinformatics and Computational Biology, 147–66. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2005. http://dx.doi.org/10.1002/0471756504.ch6.
Full textErciyes, K. "Introduction to Molecular Biology." In Computational Biology, 11–25. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24966-7_2.
Full textWaterman, Michael S. "Some Molecular Biology." In Introduction to Computational Biology, 5–27. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-6846-3_2.
Full textOprea, Tudor I., Elebeoba E. May, Andrei Leitão, and Alexander Tropsha. "Computational Systems Chemical Biology." In Methods in Molecular Biology, 459–88. Totowa, NJ: Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-839-3_18.
Full textLodola, Alessio, and Adrian J. Mulholland. "Computational Enzymology." In Methods in Molecular Biology, 67–89. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-017-5_4.
Full textMahon, Annette S. "A Molecular Supertree of the Artiodactyla." In Computational Biology, 411–37. Dordrecht: Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2330-9_20.
Full textTiwary, Basant K. "Molecular Evolution." In Bioinformatics and Computational Biology, 87–116. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-4241-8_6.
Full textVallabhajosyula, Ravishankar R., and Alpan Raval. "Computational Modeling in Systems Biology." In Methods in Molecular Biology, 97–120. Totowa, NJ: Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-800-3_5.
Full textKo, Jason M., Reza Mousavi, and Daniel Lobo. "Computational Systems Biology of Morphogenesis." In Methods in Molecular Biology, 343–65. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-1831-8_14.
Full textSöllner, Johannes. "Computational Peptide Vaccinology." In Methods in Molecular Biology, 291–312. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-2285-7_13.
Full textConference papers on the topic "Computational Molecular Biology"
Donald, Bruce R. "Computational and physical modeling challenges in structural molecular biology and proteomics." In the 2005 ACM symposium. New York, New York, USA: ACM Press, 2005. http://dx.doi.org/10.1145/1060244.1060245.
Full textWei, Guopeng, Connor Walsh, Irina Cazan, and Radu Marculescu. "Molecular tweeting." In BCB '15: ACM International Conference on Bioinformatics, Computational Biology and Biomedicine. New York, NY, USA: ACM, 2015. http://dx.doi.org/10.1145/2808719.2808757.
Full textYang, J. Y., A. Niemierko, M. Q. Yang, Zuojie Luo, and Jianling Li. "Predicting Tumor Malignancies using Combined Computational Intelligence, Bioinformatics and Laboratory Molecular Biology Approaches." In 2007 4th Symposium on Computational Intelligence in Bioinformatics and Computational Biology. IEEE, 2007. http://dx.doi.org/10.1109/cibcb.2007.4221203.
Full textKhudyakov, Yury, Ion Mandoiu, Pavel Skums, and Alexander Zelikovsky. "Workshop on Computational Advances in Molecular Epidemiology." In BCB '19: 10th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics. New York, NY, USA: ACM, 2019. http://dx.doi.org/10.1145/3307339.3343859.
Full textRoychowdhury, Jaijeet. "Session details: Repurposing I.C. CAD computational techniques for molecular and cell biology." In DAC '11: The 48th Annual Design Automation Conference 2011. New York, NY, USA: ACM, 2011. http://dx.doi.org/10.1145/3256179.
Full text"“Dynamic molecular portraits” of biomembranes: a computational insight." In Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022) :. Institute of Cytology and Genetics, the Siberian Branch of the Russian Academy of Sciences, 2022. http://dx.doi.org/10.18699/sbb-2022-159.
Full textMa, Hehuan, Feng Jiang, Yu Rong, Yuzhi Guo, and Junzhou Huang. "Robust self-training strategy for various molecular biology prediction tasks." In BCB '22: 13th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics. New York, NY, USA: ACM, 2022. http://dx.doi.org/10.1145/3535508.3545998.
Full text"Computational design of molecular probes targeting CD95 signaling pathway." In Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022) :. Institute of Cytology and Genetics, the Siberian Branch of the Russian Academy of Sciences, 2022. http://dx.doi.org/10.18699/sbb-2022-581.
Full textMuhamedyev, Ravil I., Y. Daineko, D. Bari, and Alma T. Mansharipova. "Using computational models for development of the three-dimensional visualization in molecular biology." In 2014 IEEE 8th International Conference on Application of Information and Communication Technologies (AICT). IEEE, 2014. http://dx.doi.org/10.1109/icaict.2014.7036006.
Full textRasheed, Muhibur, Nathan Clement, Abhishek Bhowmick, and Chandrajit Bajaj. "Statistical Framework for Uncertainty Quantification in Computational Molecular Modeling." In BCB '16: ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics. New York, NY, USA: ACM, 2016. http://dx.doi.org/10.1145/2975167.2975182.
Full textReports on the topic "Computational Molecular Biology"
Taylor, Ronald C. Automated insertion of sequences into a ribosomal RNA alignment: An application of computational linguistics in molecular biology. Office of Scientific and Technical Information (OSTI), November 1991. http://dx.doi.org/10.2172/10108317.
Full textTaylor, R. C. Automated insertion of sequences into a ribosomal RNA alignment: An application of computational linguistics in molecular biology. Office of Scientific and Technical Information (OSTI), November 1991. http://dx.doi.org/10.2172/6057182.
Full textHawkins, Brian T., and Sonia Grego. A Better, Faster Road From Biological Data to Human Health: A Systems Biology Approach for Engineered Cell Cultures. RTI Press, June 2017. http://dx.doi.org/10.3768/rtipress.2017.rb.0015.1706.
Full textSheinerman, Felix. Report on the research conducted under the funding of the Sloan foundation postdoctoral fellowship in Computational Molecular Biology [Systematic study of protein-protein complexes] Final report. Office of Scientific and Technical Information (OSTI), June 2001. http://dx.doi.org/10.2172/810580.
Full textAgresar, Grenmarie, and Michael A. Savageau. Final Report, December, 1999. Sloan - US Department of Energy joint postdoctoral fellowship in computational molecular biology [Canonical nonlinear methods for modeling and analyzing gene circuits and spatial variations during pattern formation in embryonic development]. Office of Scientific and Technical Information (OSTI), December 1999. http://dx.doi.org/10.2172/811376.
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