Relevant bibliographies by topics / Comma 3 e 73

Academic literature on the topic 'Comma 3 e 73'

Author: Grafiati
Published: 9 March 2023
Last updated: 10 March 2023

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Journal articles on the topic "Comma 3 e 73"

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Corbaz, Jocelyn, William G. Blakeney, George Athwal, and Stefan Bauer. "The Use of the Comma Sign and Tissue for Recognition, Reduction, and Stability During Arthroscopic Repair of Combined Anterosuperior Cuff Tears." Video Journal of Sports Medicine 1, no. 4 (July 2021): 263502542110111. http://dx.doi.org/10.1177/26350254211011183.

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Background: The comma sign is a useful marker for combined retracted supraspinatus and subscapularis tears. It was first described by the group of Burkhart as a “composite ligamentous structure” of the rotator interval attached to the retracted subscapularis. However, Neyton and coworkers suggested that the ruptured superior part of subscapularis is pulled upward by supraspinatus retraction. This video illustrates the value of “comma” recognition for reduction and repair stability. We feel that the comma tissue can be a composition of rotator interval ligaments with or without superior subscapularis contribution depending on an associated cleavage tear. Indications: Patients with retracted anterosuperior tears, unless muscle quality is poor (Goutallier classification ≥3). Understanding of the comma tissue is difficult but of crucial importance to assess complex anterosuperior cuff tears for reduction and repair with stability by maintaining and integrating this comma link into the repair construct. Technique Description: Arthroscopic setup includes beach chair position, armholder, cerebral saturation monitoring (target mean arterial blood pressure of about 70 mm Hg). Previously described circumferential portals were used for a repair with a double row construct (4 medial anchors: 2.5 for subscapularis; 1.5 for supraspinatus) and 2 lateral anchors. The superior boarder of subscapularis as well as the retracted capsular layer of supraspinatus was reduced and fixed using a lasso loop technique. Key stages are (1) tendon manipulation with 2 traction sutures; (2) tendon release; (3) comma reduction; (4) footprint preparation (burr, microfracture); (5) retrograde suture passing; (6) knot tying, knotless lateral row; and (7) a close surgeon to physiotherapist rehabilitation link (6 weeks passive to 90°, no resistance training for 3-6 months). Results: Senior author’s (S.B.) series: 32 anterosuperior tears over 4 years (mean age: 62 years, 48-73 years), minimum follow-up 1 year showed good results (mean SSV: 85% [preop. 35%], range: 40%-95%; mean Constant: 82 [preop. 30], range: 40-90). One major complication (cutibacterium infection; brick layer; workers compensation; invalidity demand; Constant/Subjective Shoulder Value both 40) and minor temporary stiffness at 3 months (8 patients; 22%). Conclusion: Adequate reduction and comma integration into a solid repair construct, as well as responsible rehabilitation surveillance, deliver successful results after technically intricate anterosuperior repairs.
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Eisenstein, R. S., and J. M. Rosen. "Both cell substratum regulation and hormonal regulation of milk protein gene expression are exerted primarily at the posttranscriptional level." Molecular and Cellular Biology 8, no. 8 (August 1988): 3183–90. http://dx.doi.org/10.1128/mcb.8.8.3183-3190.1988.

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The mechanism by which individual peptide and steroid hormones and cell-substratum interactions regulate milk protein gene expression has been studied in the COMMA-D mammary epithelial cell line. In the presence of insulin, hydrocortisone, and prolactin, growth of COMMA-D cells on floating collagen gels in comparison with that on a plastic substratum resulted in a 2.5- to 3-fold increase in the relative rate of beta-casein gene transcription but a 37-fold increase in beta-casein mRNA accumulation. In contrast, whey acidic protein gene transcription was constitutive in COMMA-D cells grown on either substratum, but its mRNA was unstable and little intact mature mRNA was detected. Culturing COMMA-D cells on collagen also promoted increased expression of other genes expressed in differentiated mammary epithelial cells, including those encoding alpha- and gamma-casein, transferrin, malic enzyme, and phosphoenolpyruvate carboxykinase but decreased the expression of actin and histone genes. Using COMMA-D cells, we defined further the role of individual hormones in influencing beta-casein gene transcription. With insulin alone, a basal level of beta-casein gene transcription was detected in COMMA-D cells grown on floating collagen gels. Addition of prolactin but not hydrocortisone resulted in a 2.5- to 3.0-fold increase in beta-casein gene transcription, but both hormones were required to elicit the maximal 73-fold induction in mRNA accumulation. This posttranscriptional effect of hormones on casein mRNA accumulation preceded any detectable changes in the relative rate of transcription. Thus, regulation by both hormones and cell substratum of casein gene expression is exerted primarily at the post transcriptional level.
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Eisenstein, R. S., and J. M. Rosen. "Both cell substratum regulation and hormonal regulation of milk protein gene expression are exerted primarily at the posttranscriptional level." Molecular and Cellular Biology 8, no. 8 (August 1988): 3183–90. http://dx.doi.org/10.1128/mcb.8.8.3183.

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The mechanism by which individual peptide and steroid hormones and cell-substratum interactions regulate milk protein gene expression has been studied in the COMMA-D mammary epithelial cell line. In the presence of insulin, hydrocortisone, and prolactin, growth of COMMA-D cells on floating collagen gels in comparison with that on a plastic substratum resulted in a 2.5- to 3-fold increase in the relative rate of beta-casein gene transcription but a 37-fold increase in beta-casein mRNA accumulation. In contrast, whey acidic protein gene transcription was constitutive in COMMA-D cells grown on either substratum, but its mRNA was unstable and little intact mature mRNA was detected. Culturing COMMA-D cells on collagen also promoted increased expression of other genes expressed in differentiated mammary epithelial cells, including those encoding alpha- and gamma-casein, transferrin, malic enzyme, and phosphoenolpyruvate carboxykinase but decreased the expression of actin and histone genes. Using COMMA-D cells, we defined further the role of individual hormones in influencing beta-casein gene transcription. With insulin alone, a basal level of beta-casein gene transcription was detected in COMMA-D cells grown on floating collagen gels. Addition of prolactin but not hydrocortisone resulted in a 2.5- to 3.0-fold increase in beta-casein gene transcription, but both hormones were required to elicit the maximal 73-fold induction in mRNA accumulation. This posttranscriptional effect of hormones on casein mRNA accumulation preceded any detectable changes in the relative rate of transcription. Thus, regulation by both hormones and cell substratum of casein gene expression is exerted primarily at the post transcriptional level.
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Gaudet, L., L. Eliyahu, J. Lowes, J. Beach, M. Mrazik, G. Cummings, K. Latoszek, L. Carroll, B. R. Holroyd, and B. H. Rowe. "P057: Diagnosis for mild traumatic brain injury in three Canadian emergency departments: missed opportunities." CJEM 19, S1 (May 2017): S97. http://dx.doi.org/10.1017/cem.2017.259.

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Introduction: Patients with mild traumatic brain injury (mTBI) often present to the emergency department (ED). Incorrect diagnosis may delay appropriate treatment and recommendations for these patients, prolonging recovery. Notable proportions of missed mTBI diagnosis have been documented in children and athletes, while diagnosis of mTBI has not been examined in the general adult population. Methods: A prospective cohort study was conducted in one academic (site 1) and two non-academic (sites 2 and 3) EDs in Edmonton, Canada. On-site research assistants enrolled adult (>17 years) patients presenting within 72 hours of the injury event with clinical signs of mTBI and Glasgow comma scale score ≥13. Patient demographics, injury characteristics, and ED flow information were collected by chart review. Physician-administered questionnaires and patient interviews documented the recommendations given by emergency physicians at discharge. Bi-variable comparisons are reported using Pearson’s chi-square tests, Student’s t-tests or Mann-Whitney tests, as appropriate. Multivariate analyses were performed using logistic regression methods. Results: Overall, 130/250 enrolled patients were female, and the median age was 35. Proportions of successfully diagnosed mTBI varied significantly across study sites (Site 1: 89%; Site 2: 73%, Site 3: 53%; p>0.001). Patients without a diagnosis were less likely to receive a recommendation to follow-up with their family physician (OR=0.08; 95% CI: 0.03, 0.21) or advice about return to work (OR=0.17; 95% CI: 0.08, 0.04) or physical activity (OR=0.08; 95% CI: 0.04, 0.17). Patients with missed diagnoses had longer ED stays (median=5.0 hours; IQR: 3.8, 7.0) compared with diagnosed mTBI patients (median=3.9 hours; IQR: 3.0, 5.3). In the adjusted model, patients presenting to non-academic centers had reduced likelihood of mTBI diagnosis (Site 2: OR=0.21; 95% CI: 0.08, 0.58; Site 3: OR=0.07; 95% CI: 0.02, 0.24). Conclusion: The diagnostic accuracy of physicians assessing patients presenting with symptoms of mTBIs to these three EDs is suboptimal. The rates of missed diagnosis vary among EDs and were associated with length of ED stay. Closer examination of institutional factors, including diagnosis processes and personnel factors such as physician training, is needed to identify effective strategies to heighten the awareness of mTBI presentations.
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FAN, CHEN-MING, and H. J. SHYR. "SOME PROPERTIES OF MAXIMAL COMMA-FREE CODES." Tamkang Journal of Mathematics 29, no. 2 (June 1, 1998): 121–35. http://dx.doi.org/10.5556/j.tkjm.29.1998.4284.

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A code $A$ over a finite alphabet $X$ is a comma-free code if $A^2\cap X^+AX^+=\emptyset$, where $X$ is a finite alphabet containing more than one letter. This paper is a study of some algebraic properties of finite maximal comma-free codes. We give several characterizations on two-element comma-free codes and maximal comma-free codes. Let $X_n^m= X^n\cup X^{n+1}\cup \cdots \cup X^m$. We prove that for $n \ge 3$ , a maximal comma-free code in $X^n$ is a maximal comma-free code in the region $X_1^m\cup X^n$, $m < n/2$. We also obtain that for $X = \{a,b\}$, a maximal comma-free code in $X^3$ is a maximal comma-free code; a maximal comma-free code in $X^4$ is a maximal comma-free code in $X_1^4$; for every $n\ge 4$, there is a maximal comma-free code in $X^n$ which is not a maximal comma-free code.
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Wahyuni, Uli, and Mira Munita Sari. "KESALAHAN PENGGUNAAN EJAAN DALAM KARANGAN EKSPOSISI SISWA KELAS X MIPA 1 SMA NEGERI 3 KOTA JAMBI." Aksara: Jurnal Ilmiah Pendidikan Bahasa dan Sastra Indonesia 4, no. 1 (July 26, 2020): 125. http://dx.doi.org/10.33087/aksara.v4i1.174.

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This purpose of this research is to describe the errors of spelling in expository composition of class X MIPA 1 at SMA negeri 3 Kota Jambi academic year 2018/2019. This research used qualitative descriptive method. The data of this research was sequence of sentences of students’ writing with spelling errors. The primary data was students’ expository composition of class X MIPA 1 at SMA Negeri 3 Kota Jambi Tahun academic year 2018/2019. Based on the result of the analysis, it can be found that the errors of spelling in expository composition of students’ class X MIPA 1 semeter I SMA negeri 3 kota Jambi tahun ajaran 2018/2019 were 713 errors. The errors of spelling consists of 588 errors of using capital letter in the beginning of the sentence; 4 errors of using capital letter in the beginning of the sentence with direct quote; 10 errors of using capital letter as the first letter of nation name; 2 errors of using capital letter as the first letter of days’ name; 3 errors of capital letter as the first letter of geography;14 errors of capital letter of every word in the title of their composition. Moreover, there following errors of the use of comma is; 60 errors of comma in between of elements of explanation; 4 errors of comma before conjunction; 11 errors of comma behind the conjunction of sentences; 7 errors of comma in separating direct quote from the other parts of the sentence; 2 errors of comma in between of district or country’s name which is written in sequence; 9 errors of comma on the back of the information of the beginning of the sentence which is used to avoid error of reading.
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Tsukahara, Tetsuya, Makoto Takeda, Shun Shimohama, Osamu Ohara, and Nobuo Hashimoto. "Effects of Brain-derived Neurotrophic Factor on 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in Monkeys." Neurosurgery 37, no. 4 (October 1, 1995): 733–41. http://dx.doi.org/10.1227/00006123-199510000-00018.

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Cecci, Maddalena. "Se i beneficiari finali sono enti aventi finalità di pubblica utilità, il trasferimento in loro favore non sconta le imposte ipotecarie e catastali (CTR Lombardia, 3 gennaio 2022)." Trusts, no. 4 (August 4, 2022): 661–63. http://dx.doi.org/10.35948/1590-5586/2022.148.

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Massima Il conferimento della nuda proprietà di immobili in un trust avente quali beneficiari associazioni e fondazioni di beneficenza e Onlus sconta le imposte ipotecarie e catastali in misura fissa in quanto non comporta un reale ed effettivo trasferimento di ricchezza. In ragione dello status dei beneficiari (e in applicazione degli artt. 1, comma 2, e 10, comma 3, D.Lgs. 31 ottobre 1990, n. 347) deve in ogni caso escludersi l’applicazione dell’imposta ipotecaria e catastale in misura proporzionale.
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Valentini, Elena. "Il “doppio binario cautelare”: la tormentata disciplina degli automatismi stabiliti dall’art. 275 comma 3 C.P.P." Revista Brasileira de Direito Processual Penal 7, no. 3 (October 31, 2021): 1669. http://dx.doi.org/10.22197/rbdpp.v7i3.631.

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Il contributo è dedicato all’analisi del cosiddetto “doppio binario cautelare”, e dunque della disciplina speciale, racchiusa nel secondo e terzo periodo dell’art. 275 comma 3 c.p.p. (oltre che nell’art. 12 comma 4-bis d. lgs. 25 luglio 1998, n. 286), che prevede alcune deviazioni dalla regolamentazione generale concernente le condizioni applicative e i criteri di scelta delle misure cautelari personali. Il saggio esordisce descrivendo la normativa prevista per i reati comuni, per poi concentrarsi sul regime derogatorio previsto per particolari categorie di delitti. A tale ultimo proposito, dopo aver descritto la travagliata evoluzione che ha contrassegnato la disciplina speciale dal 1991 ad oggi, l’A. si sofferma sulle criticità che tuttora connotano questo dispositivo di particolare rigore, nelle sue diverse declinazioni, anche alla luce della posizione espressa al riguardo dalla Corte costituzionale.
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Sain, Yuliyanah, Ervin Ervin, and Sarjaniah Zur. "Young Adults’ Punctuation Error in Writing English Daily Story on Instagram." IDEAS: Journal on English Language Teaching and Learning, Linguistics and Literature 10, no. 1 (June 30, 2022): 682–99. http://dx.doi.org/10.24256/ideas.v10i1.2817.

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This research focuses on analyzing the young adult instagram users’ punctuation error on their instagram story. This present research uses qualitative design and the type is content analysis. The subjects of this research are taken from instagram users who belong to young adult instagram user and the researcher using snowball. This research employs documentation as the instrument of the study to collect the data. The findings of this research provided into 10 points; the researcher finds that there are 10 kinds of punctuation errors which are made by the young adult instagram users, they are (1) exclamation mark, (2) capital (capitalization), (3) period (full stop), (4) comma, (5) apostrophe, (6) question mark, (7) inverted comma (quotation mark), (8) ellipse, (9) hyphen, and (10) colon. The percentages of each error are exclamation mark 40.1%, capital (capitalization) 25.2%, period (full stop) 20.5%, comma 6.7%, apostrophe 2.3%, question mark 2.3%, inverted comma (quotation mark) 0.8%, hyphen 0.5%, colon 0.5%, and colon 0.2%. The findings of this study indicate that the most common punctuation error made by the young adult Instagram users was exclamation marks with a percentage of 40.1%.
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Dissertations / Theses on the topic "Comma 3 e 73"

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RONCO, STEFANO MARIA. "La nozione di imprenditore nel diritto tributario tra forma societaria e reddito d'impresa." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2015. http://hdl.handle.net/10281/87602.

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La presente ricerca intende soffermarsi sulla portata della presunzione di cui agli artt. 6, comma 3 e 73, comma 1, T.U.I.R., che – come noto- prevede un meccanismo di automatica riconduzione ex lege di ogni entrata economica prodotta dagli enti collettivi societari commerciali nell’alveo del reddito d’impresa. Si tratta, in particolare, di valutare la ragionevolezza di tale modulo impositivo alla luce del formante normativo e giurisprudenziale. La ricerca si muoverà su due versanti paralleli. In primo luogo – dopo un breve excursus di diritto commerciale - si cercherà di evidenziare come la presunzione di cui agli artt. 6, comma 3 e 73, comma 1 del T.U.I.R., presenti alcuni elementi di incoerenza tali da giustificare l’opportunità di un processo di riconsiderazione in una prospettiva de jure condendo. Ci si interrogherà, quindi, in merito alla possibilità di individuare un modulo impositivo alternativo che permetta di rappresentare con più pienezza - rispetto al criterio del collegamento in forza della forma giuridica - il profilo distintivo che caratterizza gli enti collettivi commerciali rispetto alle altre figure di enti collettivi nonché, più in generale, che possa coordinarsi meglio al complessivo modello del reddito d’impresa. In secondo luogo, si indagherà in merito alla sufficienza della forma giuridica commerciale per la collocazione di ogni entrata economica nell’alveo del reddito d’impresa. Ci si soffermerà, a tale riguardo, sulla tematica dell’abuso della forma giuridica, valutando quali possano essere le conseguenze di tale patologia. Tali profili saranno analizzati alla luce del prisma offerto dall’istituto dell’interposizione, differenziando il fenomeno dell’abuso della forma giuridica a seconda che vengano in considerazione situazione di interposizione reale e di interposizione fittizia. Si formuleranno, in ultimo, alcune riflessioni tese ad approfondire i risvolti in sede di diritto punitivo connessi all’abuso della forma giuridica, prendendo in esame, in particolare, la giurisprudenza formatasi in materia di sanzioni tributarie amministrative ed in materia di confisca in sede di diritto penale.
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De, Palma Roberta. "Le pari opportunità in Germania: l'articolo 3, comma 2 pietra miliare dell'emancipazione femminile." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2021.

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Nel mio elaborato ho voluto analizzare la questione della pari opportunità in Germania, e di come queste siano cambiate nel corso degli anni. Partendo da un'analisi del Bürgerliches Gesetzbuch, il Codice Civile Tedesco del 1900, ho esaminato l'evoluzione dei diritti delle donne durante i diversi momenti storici che si sono succeduti (Germania guglielmina, Repubblica di Weimar, Germania Nazista), fino ad arrivare al secondo dopoguerra, che si rivelò un momento decisivo per le donne. Successivamente, mi sono concentrata sulla rivoluzione legislativa promossa dalle Madri della Costituzione, fra le quali una in particolare, Elisabeth Selbert elaborò la celebre proposta di legge "Männer und Frauen sind gleichberechtigt", ovvero "Gli uomini e le donne hanno gli stessi diritti", che gettò le basi per una nazione equa e libera. Infine, ho approfondito, attraverso ricerche in ambito prevalentemente giornalistico, la condizione della donna al giorno d'oggi in Germania, mettendo in luce diverse problematiche che, in alcuni contesti lavorativi, non rendono ancora possibile una piena parità fra i sessi.
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Silva, Sílvia Mónica Santos. "Accountability: impacto da Lei nº 73/2013, de 3 de setembro." Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/13427.

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Mestrado em Contabilidade e Administração Pública
Esta dissertação teve como objetivo analisar as práticas de accountability, a transparência e o rigor da informação na Administração Pública, em particular nas Autarquias Locais. Para o efeito, foi analisada a Lei n.º 73/2013, de 3 de setembro, de forma a avaliar o impacto que as alterações provocadas por este novo normativo deverão ter no processo de accountability. Foi utilizada uma abordagem metodológica designada por Grounded Theory, caraterizada por um estilo de pesquisa qualitativa. As questões que estiveram subjacentes nesta dissertação foram respondidas no estudo exploratório e validadas com um estudo de caso ao Município de Santa Maria da Feira. Aferimos que o mesmo cumpre com todos os termos que o novo Regime Financeiro das Autarquias Locais impõe, quer ao nível do equilíbrio orçamental, quer ao nível do endividamento. Dado que dispõe de contas auditáveis desde 2007, verificamos que desde então tem vindo a melhorar consideravelmente os seus procedimentos. Relativamente ao acesso ao Fundo de Apoio Municipal, o município não reúne as condições para aceder a esse mecanismo de assistência financeira. O novo Regime Financeiro das Autarquias Locais e das Entidades Intermunicipais é um elemento potenciador de accountability no seio das Autarquias Locais.
The purpose of this dissertation was to analyze the practices of accountability, the transparency and rigor of information in Public Administration, particularly the Local Government. To this end, the Law 73/2013, of September 3rd, in order to assess the impact that the alterations provoked by this new normative will have on accountability process. A methodical approach called Grounded Theory, characterized as a qualitative research style, was applied. The subjacent questions in this dissertation were answered in the exploratory study and validated with a case study on the Municipality of Santa Maria da Feira. We consider that the above mentioned municipality fulfils with all the terms that the new Financial Regimen of Local Government enforces, on both the budget equilibrium and debt levels. Has long as, the municipality had audited accounts since 2007, we verified that since then, they have considerably improved their procedures. Concerning the access to the Municipal Support Fund, the municipality does not meet the conditions to access that mechanism of financial assistance. The new Financial Regime of Local Government and Intermunicipal Entities is a potential element of accountability within the Local Government.
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Atalan, Cayirezmez Nurdan. "Relationships Between Topography And Kerkenes (turkey), A Gis Analysis." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/3/12607786/index.pdf.

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This study investigates the effect of topography in ancient city Kerkenes using Geographic Information Systems (GIS). Kerkenes, an Iron Age city located on a batholith in Yozgat province, Turkey, was chosen because of its exceptional size, short life and the availability of extensive data. Approximately seven kilometres of city wall in Kerkenes, including towers and seven gates, enclose 2.5 km²
. The research comprises topographic analysis and settlement data analysis. Elevation values collected by Global Positioning System (GPS) and 1:25000 scaled topographic maps are used to create and analyze elevation, slope and aspect maps. Basic statistics of the city wall, towers and gates are calculated and a procedure is then followed to examine the city wall, towers and gates to understand reasons for the line of the city wall, the uneven distribution of gates, the position of each individual gate, the positions and spacing of towers, and the water catchments. Advantages of the elevated site of Kerkenes for the foundation of a new capital within the region are demonstrated. The GPS data do not show statistically significant differences then the 1:25000 scaled topographic maps in regional scale, especially analyzing the elevation and slope data. Topographic analyses reveal that approximately 75% of the city wall coincides with the topographic divide which shows the city walls may serve both for urban water collection and for defence. City wall has divided into two as East section and West section by a north-south axis from the north end point of the city. There are 41 and 27 towers are detected on the West and East section, respectively. Towers on the West section are more closely spaced than the East section. There are also two and five gates in the West and East section, respectively. The East section of the city wall overlaps with the topographic divide only in the northeastern part. This situation can not be traced along the southeastern part of Kerkenes which may be the reason to include the strategically important two higher altitude areas (Kiremitlik and Kale) inside the city. The city wall in the West section, however, runs along the topographic divide which affects the number and the distribution of the towers.
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Egemen, Ferah. "The Impacts Of The Younger Dryas Period On Plant And Animal Food Resources Of The Ancient Natufian Culture And The Economy." Master's thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/3/12611338/index.pdf.

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This masters thesis investigates the environmental/climatic change that is thought to have brought about the economic shift and transition from Palaeolithic economic system of hunting gathering to Neolithic economic system of agriculture and domestication period around 11.000-10.000 years ago. This study uses the collected animal and plant data of the Natufian culture in the Levant region from the previous zooarchaeological and archaeobotanical literature anlyses. It shows a significant mathematical difference in the zooarchaeological assemblage measures between the Early and Late Natufian sites by calculating Economic value parameters of the Early and the Late Natufian sites, a comparison analysis was made in terms of percentage frequencies of animals site by site and between early-late periods. The result shows a significant animal food supply decrease and change-shift shown during the Younger Dryas climatic crisis times of the whole Late Natufian period sites total and early to late site by site individually, compared to whole Early Natufian period sites. It shows there is a possibility that some big-base camp Late Natufian occupation sites were better able to create coping mechanisms against food crisis/food shortage and more successfully than other Late Natufian sites during the climatic food crisis period. It shows supporting with the animal-plant data and changes in the human bones, burial practices, human teeth, diet changes and anthropological studies evidence, a big social-economic-cultural change and a huge food crisis was highly possible and humans highly possibly lived an economic crisis and an highly connected-related social-cultural crisis during the Younger Dryas in the Late Natufian times human societies.
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Lieckfeldt, Jens. "Die Verfallsanordnung gegen den Drittbegünstigten : Betrachtungen zur Entwicklung und Rechtsnatur des Verfalls in ihren Auswirkungen auf die Verfallsanordnung gemäß 73 Absatz 3 StGB 30 Jahre nach Inkrafttreten des 2. StrRG /." Hamburg : Kovač, 2008. http://www.verlagdrkovac.de/978-3-8300-3534-3.htm.

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Claveras, i. Pérez Montserrat. "Crist en el cinema (La passió de Jesucrist en el cinema espanyol dins el context cinematogràfic mundial)." Doctoral thesis, Universitat Rovira i Virgili, 2006. http://hdl.handle.net/10803/8642.

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Torrents, Iglesias Ester. "La indumentaria señorial femenina catalana del Siglo XV y su reflejo en el arte." Doctoral thesis, Universitat Rovira i Virgili, 2019. http://hdl.handle.net/10803/668812.

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La indumentària és un reflex de l'ideari del moment històric en què es produeix. Tot el que veiem d'ella és una porta oberta a la idiosincràsia del període, susceptible d'analitzar-se des del punt de vista social, polític i fins i tot psicològic i moral. La moda catalana del segle XV tenia unes formes pròpies que la diferenciaven de la dels altres regnes peninsulars, per als quals va ser font d'inspiració i innovació en moltes ocasions. Aquesta tesi doctoral repassa detalladament les diferents peces de roba de les dames de la noblesa a Catalunya. S'analitzaran els materials i tints amb les que van ser elaborades, així com la seva evolució estilística, a través d'il•lustracions inèdites creades en detall al llarg de la investigació per l'autora. Així mateix, es farà una anàlisi històrica, psicològic, moral i sociològic de la indumentària, com mostra la realitat de la dona del moment i com aquesta es reflectia en el seu abillament. Finalment, s'estudiaran sis obres escultòriques i pictòriques, analitzant així la simbologia i el missatge socioeconòmic després de l'elecció de peces, colors i estils amb els quals les dames van ser retratades en elles. Tot acompanyat d'il•lustracions creades per explicar la seva morfologia. S'uneixen així Il•lustració i Història de l'Art en una investigació que pretén convertir-se en un manual de fàcil ús per a qualsevol historiador que pretengui fer una aproximació històrica i artística a qualsevol peça de roba que es trobi en una obra artística catalana del segle XV.
La indumentaria es un reflejo del ideario del momento histórico en el que se produce. Cuanto vemos de ella es una puerta abierta a la idiosincrasia del período, susceptible de analizarse desde el punto de vista social, político e incluso psicológico y moral. La moda catalana del siglo XV tenía unas formas propias que la diferenciaban de la de los demás reinos peninsulares, para los cuales fue fuente de inspiración e innovación en muchas ocasiones. Esta tesis doctoral repasa detalladamente las diferentes prendas de ropa de las damas de la nobleza en Cataluña. Se analizarán los materiales y tintes con las que fueron elaboradas, así como su evolución estilística, a través de ilustraciones inéditas creadas en detalle a lo largo de la investigación por la autora. Asimismo, se hará un análisis histórico, psicológico, moral y sociológico de la indumentaria, como muestra la realidad de la mujer del momento y cómo esta se reflejaba en su atuendo. Por último, se estudiarán seis obras escultóricas y pictóricas, analizando así la simbología y el mensaje socio-económico tras la elección de prendas, colores y estilos con los que las damas fueron retratadas en ellas. Todo acompañado de ilustraciones creadas para explicar su morfología. Se unen así Ilustración e Historia del Arte en una investigación que pretende convertirse en un manual de fácil uso para cualquier historiador que pretenda hacer una aproximación histórica y artística a cualquier prenda de ropa que se halle en una obra artística catalana del siglo XV.
The clothing is a reflection of the ideology of the historical moment in which it occurs. What we see of it is an open door to the idiosyncrasies of the period, which can be analyzed from a social, political and even psychological and moral point of view. The Catalan fashion of the fifteenth century had its own forms that differentiated it from the style of the other peninsular kingdoms. For those kingdoms Catalan fashion was a source of inspiration and innovation on many occasions. This doctoral thesis reviews in detail the different clothes of the ladies of the nobility in Catalonia. The materials and dyes with which they were made will be analyzed, as well as their stylistic evolution, through unpublished illustrations created in detail throughout the investigation by the author. Also, there will be a historical, psychological, moral and sociological analysis of the clothing, as shown by the reality of the woman of the moment and how it was reflected in her attire. Finally, six sculptural and pictorial works will be studied, analyzing the symbolism and the socioeconomic message besides the choice of garments, colors and styles in with which the ladies were portrayed.All accompanied by illustrations created to explain its morphology. Illustration and Art History are united in a research that aims to become an easy-to-use manual for any historian who intends to make a historical and artistic approach to any garment that is found in the Catalan artistic world of the fifteenth century.
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Fagerström, Emelie. "Elevers meningsindelning : Användningen av interpunktion, konnektivbindning ochsatsradningar i elevtexter från årskurs 3 i svenska och svenska som andraspråk." Thesis, Linnéuniversitetet, Institutionen för svenska språket (SV), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-44059.

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The aim of this study is to analyse how pupils in grade three use punctuation and howthey divide texts into sentences. The material in the study consists of 41 texts by pupils,divided into two types: narrative text and analytical text, written both by pupils withSwedish as their first language and by pupils with Swedish as their second language. Inthe study the pupils’ use of connectives and comma splices has been studied, and therelationship between graphical and syntactical sentences in the texts. The studycompares the results for narrative and analytical texts and the differences between L1and L2 pupils. The study is a follow-up of Per Ledin’s (1998) study of pupils’ use ofpunctuation in the low and intermediate levels of compulsory, and therefore the resultsof this study are compared with those obtained by Ledin. This study shows that in thisrespect L1 and L2 pupils produce texts that do not differ to any great extent. The mostprominent differences between the types of text are that the narrative texts have aclearer flow and a seemingly more logical link between sentences and clauses than theanalytical texts. The results of this study largely agree with Ledin’s results.
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Gil, Duran Núria. "Triple aproximació a les biennals d'art contemporani de les comarques de Tarragona: vessant estètica, sociològica i didàctica." Doctoral thesis, Universitat Rovira i Virgili, 2013. http://hdl.handle.net/10803/129166.

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La investigació presenta un triple vessant de les biennals d’art en tres àmbits diferenciats, que, alhora, s’interrelacionen: el vessant historicoartístic, el sociològic i el didàctic. En el vessant historicista de les arts visuals es realitza, per primera vegada, una anàlisi global de les manifestacions artístiques, es revisen les edicions de les biennals, les obres d’art i l’evolució dels artistes que hi han participat i la seva projecció, i es fa menció especial als guanyadors dels certàmens biennals. En el vessant sociològic, s’analitza la participació de la convocatòria al concurs, la repercussió que ha tingut en l’àmbit cultural de les respectives ciutats i si ha propiciat la creació de contextos favorables, així com la Incidència social de l’impacte mediàtic a la premsa. En el vessant didàctic, s’analitza la relació entre educació i art al llarg de la història de l’educació artística, en els diferents nivells educatius, amb el centre d’atenció a la demarcació de Tarragona, i emfatitza en l’estudi del cas de les biennals del Museu d’Art Modern de Tarragona. Paraules clau: biennal, ciències socials, educació artística, demarcació Tarragona, museu, art contemporani.
La investigación analiza un triple componente de las Bienales de Arte en tres ámbitos diferenciados, que, a su vez, se interrelacionan: la vertiente histórico-artística, la sociológica y la didáctica. En el componente historicista de las artes visuales se realiza, por primera vez, un análisis global de las manifestaciones artísticas, revisando las ediciones de las bienales, las obras y la evolución de los artistas que han participado, su proyección, haciendo mención especial de los ganadores de los certámenes bienales. En el componente sociológico se analiza la participación de la convocatoria al concurso, la repercusión que ha tenido en el ámbito cultural de las respectivas ciudades y se ha propiciado la creación contextos favorables, así como la incidencia social del impacto mediático en la prensa. En el componente didáctico, se analiza la relación entre educación y arte a lo largo de la historia de la educación artística, en los diferentes niveles educativos, con el centro de atención a la demarcación de Tarragona, enfatizando en el estudio del caso de las bienales del Museu d’Art Modern de Tarragona. Palabras clave: bienal, ciencias sociales, educación artística, demarcación Tarragona, museo, arte contemporáneo.
The research analyzes a triple component of the Art Biennials focusing on three distinct, but interrelated, areas: The art-historical, the sociological and the educational aspects. In the historicist component of the visual arts, for the first time a comprehensive analysis of the artistic production is performed, reviewing the biennial editions, the work and evolution of the participating artists and the impact of their work, with specific attention to the winners of these biennial competitions. The sociological component analyzes the participation in the call of the competition, the impact it has had on the cultural environment of the respective cities, whether it has contributed to the creation of favourable contexts and, finally, the social impact of media coverage in the press. The didactic component analyzes the relationship between education and art throughout the history of art education, at different educational levels and focused on the province of Tarragona, centred on the case study biennal of the Museu d'Art Modern de Tarragona. Keywords: biennial, social sciences, art education, Tarragona, museum, contemporary art.
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Books on the topic "Comma 3 e 73"

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Ian, Hislop, ed. The Secret diary of a Lord Gnome, aged 73 3/4. London: Private Eye, 1985.

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United States. Dept. of Veterans Affairs., ed. Dependents' Educational Assistance Program (DEA), VA Pamphlet 22-73-3, Revised November 2003. [S.l: s.n., 2005.

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W, Nichol Donald, ed. The new foundling hospital for wit: (6 parts in 3 volumes, 1768-73). London: Pickering & Chatto, 2006.

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United States. Dept. of Veterans Affairs., ed. Dependents' Educational Assistance Program (DEA), VA Pamphlet 22-73-3, Revised August 2008. [S.l: s.n., 2009.

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Lüttge, Ulrich, Wolfram Beyschlag, Burkhard Büdel, and Dennis Francis, eds. Progress in Botany Vol. 73. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-22746-2.

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Schopper, H., ed. Nuclei with Z = 61 - 73. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-30696-9.

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United States. Dept. of Veterans Affairs., ed. Dependents' Educational Assistance Program (DEA), etc., VA Pamphlet 22-73-3, Revised February 2003. [S.l: s.n., 2003.

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Kosmetatos, Paul. The 1772–73 British Credit Crisis. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-70908-6.

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United States. Dept. of the Air Force., ed. Accident investigation board report: United States Air Force CT-43A 73-1149 : 3 April 1996, Dubrovnik, Croatia. [Washington, D.C.?: Dept. of the Air Force, 1996.

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United States. Dept. of the Air Force, ed. Accident investigation board report: United States Air Force CT-43A 73-1149 : 3 April 1996, Dubrovnik, Croatia. [Washington, D.C.?: Dept. of the Air Force, 1996.

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Book chapters on the topic "Comma 3 e 73"

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Hildebrandt, Frank, and Holger Herzog. "COMMA." In Kommunikation in verteilten Systemen, 218–30. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74570-6_16.

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Fant, Kenne. "73." In Alfred Nobel, 311–12. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-6368-1_73.

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Rabina, Gilad, and Michaella Goldstein. "Comma Sign, in Sickle Cell Hemoglobinopathies." In Encyclopedia of Ophthalmology, 452–54. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-540-69000-9_1020.

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Rabina, Gilad, and Michaella Goldstein. "Comma Sign, in Sickle Cell Hemoglobinopathies." In Encyclopedia of Ophthalmology, 1–3. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-35951-4_1020-1.

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Kurtev, Ivan, and Jozef Hooman. "Runtime Verification of Compound Components with ComMA." In Lecture Notes in Computer Science, 382–402. Cham: Springer Nature Switzerland, 2022. http://dx.doi.org/10.1007/978-3-031-15629-8_21.

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Krieger, Heike. "Article 73." In Vienna Convention on the Law of Treaties, 1331–65. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-55160-8_77.

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Nguyen, Huong Lam. "Finite Completion of Comma-Free Codes. Part I." In Developments in Language Theory, 357–68. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-45005-x_32.

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Sukhoruchkin, S. I., and Z. N. Soroko. "Energy levels for Rb-73 (Rubidium-73)." In Tables of Excitations of Proton- and Neutron-Rich Unstable Nuclei, 340. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-75278-3_214.

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Xu, Shengqin, Fang Kong, Peifeng Li, and Qiaoming Zhu. "A Chinese Sentence Segmentation Approach Based on Comma." In Lecture Notes in Computer Science, 809–17. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-36337-5_82.

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Kong, Fang, and Guodong Zhou. "Chinese Comma Disambiguation on K-best Parse Trees." In Communications in Computer and Information Science, 13–22. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-45924-9_2.

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Conference papers on the topic "Comma 3 e 73"

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Scalapino, D. J., R. L. Sugar, S. R. White, N. E. Bickers, and R. T. Scalettar. "Numerical Simulations: Some Results for the 2- and 3-D Hubbard Models and a 2-D Electron Phonon Model." In Proceedings of Nobel Symposium 73. CO-PUBLISHED WITH PHYSICA SCRIPTA, THE ROYAL SWEDISH ACADEMY OF SCIENCES, 1989. http://dx.doi.org/10.1142/9789814541152_0017.

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Arman, Arman, Herix Sonata, and Y. Pangestu. "Pengaruh Pemakaian Pasir Bukit dan Pasir Sungai Terhadap Kuat Tekan Beton." In SEMINAR NASIONAL Strategi Pengembangan Infrastruktur ke-3. ITP Press, 2017. http://dx.doi.org/10.21063/spi3.1017.70-73.

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Gao, Ziye, Jiangfeng Zhu, Wenlong Tian, Junli Wang, Xiaodong Zeng, Zhaohua Wang, Zhiguo Zhang, Zhiyi Wei, and Huaijin Zhang. "Diode-pumped 73-fs Kerr-lens mode-locked Yb:YCa4O(BO3)3 laser." In CLEO: Science and Innovations. Washington, D.C.: OSA, 2014. http://dx.doi.org/10.1364/cleo_si.2014.sm4f.1.

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Kirwin, Thomas, Anthony Mechery, Vincenzo Ventrungo, Muhammad Waqas, Jonathan Townend, and sohail khan. "73 Outcomes in patients undergoing percutaneous coronary intervention with chronic kidney disease." In British Cardiovascular Society Annual Conference ‘Digital Health Revolution’ 3–5 June 2019. BMJ Publishing Group Ltd and British Cardiovascular Society, 2019. http://dx.doi.org/10.1136/heartjnl-2019-bcs.71.

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Irvine, Fiona. "P-73 Sharing is Caring – Peer to Peer Education." In A New World – Changing the landscape in end of life care, Hospice UK National Conference, 3–5 November 2021, Liverpool. British Medical Journal Publishing Group, 2021. http://dx.doi.org/10.1136/spcare-2021-hospice.91.

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Xiaolu, Zhao, and Qin Lisen. "An Approximate 3-D Aerodynamic Design Method for Centrifugal Impeller Blades." In ASME 1989 International Gas Turbine and Aeroengine Congress and Exposition. American Society of Mechanical Engineers, 1989. http://dx.doi.org/10.1115/89-gt-73.

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An aerodynamic design method, which based on the Mean Stream Surface Method (MSSM), has been developed in designing the centrifugal compressor impeller blades. As a component of a CAD system for centrifugal compressor, it is convenient to use the presented method for generating impeller blade geometry, taking care of manufacturing as well as aerodynamic aspects. The design procedure starts with an S2m indirect solution. Afterwards from the specified S2m surface, by the use of Taylor series expansion, the blade geometry is generated by straight-line elements to meet the requirement of manufacture. Simultaneously, the fluid dynamic quantities across the blade passage, can be determined directly. In terms of these results, the designer can revise the distribution of angular momentum along the shroud and hub, which are associated with blade loading to get satisfactory velocities along the blade surfaces in order to avoid or delay flow separation.
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Пьянкова, Л. А., and Т. А. Рундау. "Семья, родительство и детство как явления современной жизни." In ТЕНДЕНЦИИ РАЗВИТИЯ НАУКИ И ОБРАЗОВАНИЯ. НИЦ "Л-Журнал", 2016. http://dx.doi.org/10.18411/lj2016-3-73.

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Japikse, D. "Assessment of Single- and Two-Zone Modeling of Centrifugal Compressors, Studies in Component Performance: Part 3." In ASME 1985 International Gas Turbine Conference and Exhibit. American Society of Mechanical Engineers, 1985. http://dx.doi.org/10.1115/85-gt-73.

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Single- and two-zone modeling, as used to describe the performance of centrifugal compressors, is evaluated against basic laboratory data. The historical industrial usage of single-zone modeling is reviewed and documented while indicating inherent errors as well as areas of applicability. Enhanced accuracy of two-zone modeling (also called jet-wake modeling in limited instances) is demonstrated and advantages for advanced design optimization studies are documented. An original and rigorous derivation of the two-zone (jet-wake) modeling equations is given which resolves discrepancies in earlier derivations. This paper is part of a seven-paper series presenting the foundation, history and application of two-zone modeling.
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Zhang, Bo-lun, Hui-ren Zhu, Tao Guo, Chun-yi Yao, and Zhong-yi Fu. "Numerical Study on Heat Transfer and Flow Characteristics in Double Turning Areas Ribbed Serpentine Channel With Lateral Outflow." In ASME Turbo Expo 2019: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/gt2019-90143.

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Abstract The double turning areas ribbed serpentine channel with lateral outflow is an important structure for designing the internal systems of turbine blade. The current work similarly simplifies the internal channel of the real blade. The Nusselt number and pressure coefficient distribution of the double turning areas ribbed serpentine channel with different outflow ratios are numerically researched under static and rotating conditions. The Realizable k-ε turbulence model with enhanced wall treatment is used in the numerical simulation. The inlet Reynolds number is 11000. The rotation numbers vary from 0 to 0.09. Three outflow ratios are 27%/0%/73%, 27%/49%/24% and 27%/73%/0%, respectively. The rotation radius (R) is 46.4d. The result shows that the Nusselt number distribution of the passage 3 under 27%/49%/24% outflow ratio condition is similar to that under 27%/73%/0% outflow ratio condition. There is a large low Nusselt number area in the passage 3 under Dr = 27%/0%/73% condition. The averaged area Nusselt number ratios on the suction side of the passage 1, passage 2 and passage 3 are higher than that on the pressure side under nonrotating condition. Rotation enhances heat transfer on the suction side of the passage 2, and has a positive effect on pressure side heat transfer of passage 1 and passage 3. The averaged area Nusselt number ratio of passage 3 under 27%/73%/0% outflow ratio condition is higher than that under other outflow ratio conditions. With the rotation number increasing, the pressure coefficient of the complete ribbed serpentine channel gradually increases, and the maximum increase is in the first turning area.
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Das, Pratyusha, Rishi Maiti, Prahalad K. Barman, Samit K. Ray, and B. N. Shivakiran Bhaktha. "Spectral Management of Eu2+,3+ Emission in Sol-Gel Fabricated One-dimensional Photonic Crystals." In International Conference on Fibre Optics and Photonics. Washington, D.C.: OSA, 2014. http://dx.doi.org/10.1364/photonics.2014.m4a.73.

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Reports on the topic "Comma 3 e 73"

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Chandramouli, R., H. Ferraiolo, and K. Mehta. PIV card application and middleware interface test guidelines (SP800-73-3 compliance). Gaithersburg, MD: National Institute of Standards and Technology, 2010. http://dx.doi.org/10.6028/nist.sp.800-85a-2.

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Young, M. A., S. P. Salamy, T. K. Reeves, W. C. Kimbrell, and W. K. Sawyer. Volume 3: Characterization of representative reservoirs -- South Marsh Island 73, B35K and B65G Reservoirs. Office of Scientific and Technical Information (OSTI), July 1998. http://dx.doi.org/10.2172/661389.

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Task, Richard P., William Jenkins, Jeffrey Sherman, Neil McPhee, and William Ostrom. The Subduction Experiment, Cruise Report, RRS Charles Darwin Cruise Number 73. Subduction 3 Mooring Deployment and Recovery Cruise 30 September-26 October 1992. Fort Belvoir, VA: Defense Technical Information Center, March 1993. http://dx.doi.org/10.21236/ada265387.

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Batchelder, Jon Charles. Extension of the Tz = -3/2, A = 4n + 1 series of beta-delayed proton emitters to 65Se and 73Sr, and low energy beta-delayed proton emission from the Tz = -3/2, A = 4n + 3 nucleus 23Al. Office of Scientific and Technical Information (OSTI), December 1993. http://dx.doi.org/10.2172/10125553.

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Schipper, Youdi, Isaac Mbiti, and Mauricio Romero. Designing and Testing a Scalable Teacher Incentive Programme in Tanzania. Research on Improving Systems of Education (RISE), September 2022. http://dx.doi.org/10.35489/bsg-rise-ri_2022/044.

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School participation in Tanzania has increased dramatically over the past two decades: primary school enrolment increased from 4.9 million in 2001 to 10.9 million in 2020. While 81 percent of primary-school-age children are currently enrolled, over the last ten years, the primary completion rate has dropped and remains below 70 percent since 2015 (data from UNESCO Institute for Statistics).1 Despite improvements in enrolment, indicators of foundational learning remain low. According to the 2020 report of the Standard Two National Assessment (STNA), conducted by the National Examinations Council of Tanzania (NECTA), in 2019 five percent of Grade 2 students pass the benchmark for reading proficiency (“Can correctly read exactly 50 words of the passage in one minute and with 80 percent or higher comprehension”). The report finds that 17 percent of students pass the benchmark (80 percent correct) of the addition and subtraction sub-tasks. These outcomes are not the result of students’ lack of academic aspiration: according to the RISE Tanzania baseline survey, 73 percent of Grade 2 and 3 students say they would like to complete secondary school or university. In a recent report, the Global Education Evidence Advisory Panel (World Bank, 2020) asked what programmes and policies are the most cost-effective instruments for addressing the learning crisis and improving learning for all children. The report creates three categories: the “great buys” category includes programmes that provide very low-cost but salient information on the benefits, costs, and quality of education. The “good buys” category includes programmes that provide structured pedagogy, instruction targeted by learning level, merit-based scholarships and pre-school interventions. Finally, the category “promising but low-evidence” includes teacher accountability and incentive reforms. KiuFunza, a teacher performance pay programme in Tanzania, fits this last category. KiuFunza (shorthand for Kiu ya Kujifunza or Thirst to Learn) provides test-score linked cash incentives to teachers in Grades 1, 2, and 3 to increase foundational literacy and numeracy outcomes for students. The programme is managed by Twaweza East Africa, a Civil Society Organization, and was set up to provide evidence on the impact of teacher incentives in a series of experimental evaluations. This note discusses the rationale for teacher incentives in Tanzania, the design elements of KiuFunza and preliminary results for the most recent phase of KiuFunza (this phase was implemented in 2019-2021 and the impact evaluation is part of the RISE Tanzania research agenda).
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Wisniewski, Michael, Samir Droby, John Norelli, Dov Prusky, and Vera Hershkovitz. Genetic and transcriptomic analysis of postharvest decay resistance in Malus sieversii and the identification of pathogenicity effectors in Penicillium expansum. United States Department of Agriculture, January 2012. http://dx.doi.org/10.32747/2012.7597928.bard.

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Use of Lqh2 mutants (produced at TAU) and rNav1.2a mutants (produced at the US side) for identifying receptor site-3: Based on the fact that binding of scorpion alpha-toxins is voltage-dependent, which suggests toxin binding at the mobile voltage-sensing region, we analyzed which of the toxin bioactive domains (Core-domain or NC-domain) interacts with the DIV Gating-module of rNav1.2a. This analysis was based on the assumption that the dissociation of toxin mutants upon depolarization would vary from that of the unmodified toxin should the substitutions affect a site of interaction with the channel Gating-module. Using a series of toxin mutants (mutations at both domains) and two channel mutants that were shown to reduce the sensitivity to scorpion alpha-toxins, and by comparison of depolarization-driven dissociation of Lqh2 derivatives off their binding site at rNav1.2a mutant channels we found that the toxin Core-domain interacts with the Gating-module of DIV. Details of the experiments and results appear in Guret al (2011). Mapping receptor site 3 at Nav1.2a by extensive channel mutagenesis (Seattle): Since previous studies with photoaffinity labeling and antibody mapping implicated domains I and IV in scorpion alpha-toxin binding, Nav1.2 channel mutants containing substitutions at these extracellular regions were expressed and tested for receptor function by whole-cell voltage clamp. Of a large number of channel mutants, T1560A, F1610A, and E1613A in domain IV had ~5.9-, ~10.7-, and ~3.9-fold lower affinities for the scorpion toxin Lqh2, respectively, and mutant E1613R had 73-fold lower affinity. Toxin dissociation was accelerated by depolarization for both wild-type and mutants, and the rates of dissociation were also increased by mutations T1560A, F1610A and E1613A. In contrast, association rates for these three mutant channels at negative membrane potentials were not significantly changed and were not voltage-dependent. These results indicated that Thr1560 in the S1-S2 loop, Phe1610 in the S3 segment, and Glu1613 in the S3-S4 loop in domain IV participate in toxin binding. T393A in the SS2-S6 loop in domain I also showed a ~3.4-fold lower affinity for Lqh2, indicating that this extracellular loop may form a secondary component of the toxin binding site. Analysis with the Rosetta-Membrane algorithm revealed a three-dimensional model of Lqh2 binding to the voltage sensor in a resting state. In this model, amino acid residues in an extracellular cleft formed by the S1-S2 and S3-S4 loops in domain IV that are important for toxin binding interact with amino acid residues on two faces of the wedge-shaped Lqh2 molecule that are important for toxin action. The conserved gating charges in the S4 transmembrane segment are in an inward position and likely form ion pairs with negatively charged amino acid residues in the S2 and S3 segments (Wang et al 2011; Gurevitz 2012; Gurevitzet al 2013).
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7

McDonagh, Marian, Andrea C. Skelly, Amy Hermesch, Ellen Tilden, Erika D. Brodt, Tracy Dana, Shaun Ramirez, et al. Cervical Ripening in the Outpatient Setting. Agency for Healthcare Research and Quality (AHRQ), March 2021. http://dx.doi.org/10.23970/ahrqepccer238.

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Objectives. To assess the comparative effectiveness and potential harms of cervical ripening in the outpatient setting (vs. inpatient, vs. other outpatient intervention) and of fetal surveillance when a prostaglandin is used for cervical ripening. Data sources. Electronic databases (Ovid® MEDLINE®, Embase®, CINAHL®, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews) to July 2020; reference lists; and a Federal Register notice. Review methods. Using predefined criteria and dual review, we selected randomized controlled trials (RCTs) and cohort studies of cervical ripening comparing prostaglandins and mechanical methods in outpatient versus inpatient settings; one outpatient method versus another (including placebo or expectant management); and different methods/protocols for fetal surveillance in cervical ripening using prostaglandins. When data from similar study designs, populations, and outcomes were available, random effects using profile likelihood meta-analyses were conducted. Inconsistency (using I2) and small sample size bias (publication bias, if ≥10 studies) were assessed. Strength of evidence (SOE) was assessed. All review methods followed Agency for Healthcare Research and Quality Evidence-based Practice Center methods guidance. Results. We included 30 RCTs and 10 cohort studies (73% fair quality) involving 9,618 women. The evidence is most applicable to women aged 25 to 30 years with singleton, vertex presentation and low-risk pregnancies. No studies on fetal surveillance were found. The frequency of cesarean delivery (2 RCTs, 4 cohort studies) or suspected neonatal sepsis (2 RCTs) was not significantly different using outpatient versus inpatient dinoprostone for cervical ripening (SOE: low). In comparisons of outpatient versus inpatient single-balloon catheters (3 RCTs, 2 cohort studies), differences between groups on cesarean delivery, birth trauma (e.g., cephalohematoma), and uterine infection were small and not statistically significant (SOE: low), and while shoulder dystocia occurred less frequently in the outpatient group (1 RCT; 3% vs. 11%), the difference was not statistically significant (SOE: low). In comparing outpatient catheters and inpatient dinoprostone (1 double-balloon and 1 single-balloon RCT), the difference between groups for both cesarean delivery and postpartum hemorrhage was small and not statistically significant (SOE: low). Evidence on other outcomes in these comparisons and for misoprostol, double-balloon catheters, and hygroscopic dilators was insufficient to draw conclusions. In head to head comparisons in the outpatient setting, the frequency of cesarean delivery was not significantly different between 2.5 mg and 5 mg dinoprostone gel, or latex and silicone single-balloon catheters (1 RCT each, SOE: low). Differences between prostaglandins and placebo for cervical ripening were small and not significantly different for cesarean delivery (12 RCTs), shoulder dystocia (3 RCTs), or uterine infection (7 RCTs) (SOE: low). These findings did not change according to the specific prostaglandin, route of administration, study quality, or gestational age. Small, nonsignificant differences in the frequency of cesarean delivery (6 RCTs) and uterine infection (3 RCTs) were also found between dinoprostone and either membrane sweeping or expectant management (SOE: low). These findings did not change according to the specific prostaglandin or study quality. Evidence on other comparisons (e.g., single-balloon catheter vs. dinoprostone) or other outcomes was insufficient. For all comparisons, there was insufficient evidence on other important outcomes such as perinatal mortality and time from admission to vaginal birth. Limitations of the evidence include the quantity, quality, and sample sizes of trials for specific interventions, particularly rare harm outcomes. Conclusions. In women with low-risk pregnancies, the risk of cesarean delivery and fetal, neonatal, or maternal harms using either dinoprostone or single-balloon catheters was not significantly different for cervical ripening in the outpatient versus inpatient setting, and similar when compared with placebo, expectant management, or membrane sweeping in the outpatient setting. This evidence is low strength, and future studies are needed to confirm these findings.
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8

Ziesler, Pamela, and Claire Spalding. Statistical abstract: 2021. National Park Service, May 2022. http://dx.doi.org/10.36967/nrds-2293345.

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In 2021, recreation visits to National Park Service (NPS) sites rebounded from the COVID-19 pandemic-driven low visitation of 2020 and climbed to 297,115,406 recreation visits. This is an increase of 60 million recreation visits (+25.3%) from 2020 and a decrease of 30 million recreation visits (-9.3%) from 2019. Recreation visitor hours were 1,356,657,749 – a 28.6% increase from 2020 and a 5.1% decrease from 2019. Total overnight stays followed a similar pattern with 12,745,455 overnight stays – up 4.7 million (+58.5%) from 2020 and down 1.1 million (-8%) from 2019. Five parks were added to the reporting system in 2021: Alagnak Wild River in Alaska, Camp Nelson National Monument in Kentucky, Medgar and Myrlie Evers Home National Monument in Mississippi, Tule Springs Fossil Beds National Monument in Nevada, and World War I Memorial in Washington, D.C. These parks were responsible for over 629,000 recreation visits in 2021. Factors influencing visits to National Park System units in 2021 include: continuing closures and limited capacities due to COVID-19 mitigation at some parks, temporary closures for wildland fires in 2021 (eleven parks), severe regional smoke/haze from ongoing wildland fires throughout the summer and early autumn affecting parks in the western half and northern tier of states in the continental U.S., two hurricanes in 2021 – both in August – impacted visitation: Hurricane Henri caused temporary closures of some parks in the northeast and Hurricane Ida caused temporary closures of parks along the Gulf Coast and generated some heavy flooding in the northeast, hurricanes and wildland fires in previous years resulting in lingering closures, most notably Hurricanes Irma and Maria in 2017, the Carr and Woolsey Fires in 2018, Hurricane Dorian in 2019, the Caldwell, Cameron Peak, East Troublesome, and Woodward Fires in 2020, and Hurricane Sally in 2020. Forty-four parks set a record for recreation visits in 2021 and 6 parks broke a record they set in 2020. See Appendix A for a list of record parks. The number of reporting units with over 10 million recreation visits was the same as in recent years (3 parks) and 73 parks had over 1 million recreation visits. Twenty-five percent of total recreation visits occurred in the top 8 parks and fifty percent of total visitation occurred in the top 25 parks. Several parks passed annual visitation milestones including Capulin Volcano NM which passed 100,000 annual recreation visits for the first time, Big Bend NP and Devils Tower NM which each passed 500,000 annual recreation visits for the first time, and Zion NP which passed 5 million visits for the first time. Other parks passed milestones for accumulated recreation visits including Hamilton Grange NMEM (1968-2021) and Palo Alto Battlefield NHP (2003-2021) each passing 1 million total recreation visits, Voyageurs NP (1976-2021) passing 10 million total recreation visits, and Hot Springs NP (1904-2021) passing 100 million total recreation visits. Population center designations were updated in 2021 to reflect overlap of park boundaries with statistical areas from the 2020 U.S. Census. Many population center changes reflect increases in local population as indicated by parks changing from rural to outlying or from outlying to suburban. Other changes reflect increasing complexity in population density as parks changed from a single designation, such as rural or suburban, to a mixed designation. See the Definitions section for population center definitions and Table B.1 for previous and updated population center designations by park. In the pages that follow, a series of tables and figures display visitor use data for calendar year 2021. By documenting these visits across the National Park System, the NPS Statistical Abstract offers a historical record of visitor use in parks and provides NPS staff and partners with a useful tool for effective management and planning. In 2021, 394 of 423 NPS units...
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9

Goetsch, Arthur L., Yoav Aharoni, Arieh Brosh, Ryszard (Richard) Puchala, Terry A. Gipson, Zalman Henkin, Eugene D. Ungar, and Amit Dolev. Energy Expenditure for Activity in Free Ranging Ruminants: A Nutritional Frontier. United States Department of Agriculture, June 2009. http://dx.doi.org/10.32747/2009.7696529.bard.

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Heat production (HP) or energy expenditure for activity (EEa) is of fundamental nutritional importance for livestock because it determines the proportion of ingested nutrients available for productive functions. Previous estimates of EEa are unreliable and vary widely with different indirect methodologies. This leads to erroneous nutritional strategies, especially when intake on pasture does not meet nutritional requirements and supplementation is necessary for acceptable production. Therefore, the objective of this project was to measure EEa in different classes of livestock (beef cattle and goats) over a wide range of ecological and management conditions to develop and evaluate simple means of prediction. In the first study in Israel, small frame (SF) and large frame (LF) cows (268 and 581 kg) were monitored during spring, summer, and autumn. Feed intake by SF cows per unit of metabolic weight was greater (P < 0.001) than that by LF cows in both spring and summer and their apparent selection of higher quality herbage in spring was greater (P < 0.10) than that of LF cows. SF cows grazed more hours per day and walked longer distances than the LF cows during all seasons. The coefficient of specific costs of activities (kJ•kg BW-0.75•d-1) and of locomotion (J•kg BW-0.75•m-1) were smaller for the SF cows. In the second study, cows were monitored in March, May, and September when they grazed relatively large plots, 135 and 78 ha. Energy cost coefficients of standing, grazing, and horizontal locomotion derived were similar to those of the previous study based on data from smaller plots. However, the energy costs of walking idle and of vertical locomotion were greater than those found by Brosh et al. (2006) but similar to those found by Aharoni et al. (2009). In the third study, cows were monitored in February and May in a 78-ha plot with an average slope of 15.5°, whereas average plot slopes of the former studies ranged between 4.3 and 6.9°. Energy cost coefficients of standing, grazing, and walking idle were greater than those calculated in the previous studies. However, the estimated energy costs of locomotion were lower in the steeper plot. A comparison on a similar HP basis, i.e., similar metabolizable energy (ME) intake, shows that the daily energy spent on activities in relation to daily HP increased by 27% as the average plot slope increased from 5.8 and 6.02 to 15.5°. In the fourth study, cows grazing in a woodland habitat were monitored as in previous studies in December, March, and July. Data analysis is in progress. In the first US experiment, Boer and Spanish does with two kids were used in an experiment beginning in late spring at an average of 24 days after kidding. Two does of each breed resided in eight 0.5-ha grass/forb pastures. Periods of 56, 60, 63, 64, and 73 days in length corresponded to mid-lactation, early post-weaning, the late dry period, early gestation, and mid-gestation. EEa expressed as a percentage of the ME requirement for maintenance plus activity in confinement (EEa%) was not influenced by stocking rate, breed, or period, averaging 49%. Behavioral activities (e.g., time spent grazing, walking, and idle, distance traveled) were not highly related to EEa%, although no-intercept regressions against time spent grazing/eating and grazing/eating plus walking indicated an increase in EEa% of 5.8 and 5.1%/h, respectively. In the second study, animal types were yearling Angora doeling goats, yearling Boer wether goats, yearling Spanish wether goats, and Rambouilletwether sheep slightly more than 2 yr of age. Two animals of each type were randomly allocated to one of four pastures 9.3, 12.3, 4.6, and 1.2 ha in area. The experiment was conducted in the summer with three periods, 30, 26, and 26 days in length. EEa% was affected by an interaction between animal type and period (Angora: 16, 17, and 15; Boer: 60, 67, and 34; Spanish: 46, 62, and 42; sheep: 22, 12, and 22% in periods 1, 2, and 3, respectively (SE = 6.1)). EEa% of goats was predicted with moderate accuracy (R2 = 0.40-0.41) and without bias from estimates of 5.8 and 5.1%/h spent grazing/eating and grazing/eating plus walking, respectively, determined in the first experiment; however, these methods were not suitable for sheep. These methods of prediction are simpler and more accurate than currently recommended for goats by the National Research Council.
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