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1

Powell, Steven M. Colorectal Cancer. New Jersey: Humana Press, 2000. http://dx.doi.org/10.1385/1592590845.

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2

Service, Gastrointestinal Oncology. COLORECTAL CANCER. Abingdon, UK: Taylor & Francis, 1988. http://dx.doi.org/10.4324/9780203213650.

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3

Scholefield, John H., and Cathy Eng, eds. Colorectal Cancer. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118337929.

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4

Hardcastle, Jack Donald, ed. Colorectal Cancer. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78225-1.

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5

Brown, Gina, ed. Colorectal Cancer. Cambridge: Cambridge University Press, 2007. http://dx.doi.org/10.1017/cbo9780511902468.

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6

Seitz, Helmut Karl, Ulrich A. Simanowski, and Nicholas A. Wright, eds. Colorectal Cancer. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-85930-4.

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7

Ponz de Leon, Maurizio. Colorectal Cancer. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-642-56008-8.

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8

Markman, Maurie, and Leonard B. Saltz, eds. Colorectal Cancer. Totowa, NJ: Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-215-1.

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9

Saltz, Leonard B., ed. Colorectal Cancer. Totowa, NJ: Humana Press, 2002. http://dx.doi.org/10.1007/978-1-59259-160-2.

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10

Beaulieu, Jean-François, ed. Colorectal Cancer. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7765-9.

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11

Hayat, M. A., ed. Colorectal Cancer. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-1-4020-9545-0.

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12

G, Guillem José, and Sigurdson Elin R, eds. Colorectal cancer. Philadelphia: W.B. Saunders Co., 2002.

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13

P, Boyle, Kerr David J, and McArdle C. S, eds. Colorectal cancer. Oxford: Isis Medical Media, 2000.

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14

M, Goldberg Stanley, and Garcia-Aguilar Julio, eds. Colorectal cancer. Oxford: Health Press, 1999.

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15

1935-, Skarin Arthur T., and Saunders Mark, eds. Colorectal cancer. Edinburgh: Elsevier, 2007.

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16

Cady, Blake, and David A. Rothenberger. Colorectal cancer. Philadelphia: W.B. Saunders Company, 2000.

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17

Swan, Elaine. Colorectal Cancer. New York: John Wiley & Sons, Ltd., 2006.

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18

J, Murray John, ed. Colorectal cancer. Philadelphia: Saunders, 1993.

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19

Programme, Macmillan Professional Resources, and University of Dundee. Centre for Medical Education., eds. Colorectal cancer. London: Macmillan Cancer Relief, 1999.

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20

1921-, Franks L. M., and Northover John, eds. Colorectal cancer. Oxford: Oxford University Press for the Imperial Cancer ResearchFund, 1989.

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21

Murray, John J., M.D., ed. Colorectal cancer. Philadelphia: Saunders, 1993.

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22

D, Luk Gordon, ed. Colorectal cancer. Philadelphia: Saunders, 1988.

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23

Taylor, Irving. Colorectal Cancer. 3rd ed. Abingdon: HEALTH Press, 2010.

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24

Imperial Cancer Research Fund (Great Britain). Colorectal cancer. Edited by Northover John. Oxford, U.K: Published for the Imperial Cancer Research Fund by Oxford University Press, 1989.

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25

1935-, Wanebo Harold J., ed. Colorectal cancer. St. Louis: Mosby, 1993.

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26

Elaine, Swan, ed. Colorectal cancer. London: Whurr, 2005.

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27

Chiu, Han-Mo, and Hsiu-Hsi Chen, eds. Colorectal Cancer Screening. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-7482-5.

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28

Shaukat, Aasma, and John I. Allen, eds. Colorectal Cancer Screening. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2333-5.

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29

Utsunomiya, Joji, and Henry T. Lynch, eds. Hereditary Colorectal Cancer. Tokyo: Springer Japan, 1990. http://dx.doi.org/10.1007/978-4-431-68337-7.

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30

Rodriguez-Bigas, Miguel A., Raul Cutait, Patrick M. Lynch, Ian Tomlinson, and Hans F. A. Vasen, eds. Hereditary Colorectal Cancer. Boston, MA: Springer US, 2010. http://dx.doi.org/10.1007/978-1-4419-6603-2.

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31

Anderson, MD, Joseph, and Charles Kahi, MD, eds. Colorectal Cancer Screening. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-60761-398-5.

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32

Valle, Laura, Stephen B. Gruber, and Gabriel Capellá, eds. Hereditary Colorectal Cancer. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-74259-5.

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33

Productions, Jack Digital, and Princess Margaret Hospital, eds. Understanding colorectal cancer. Toronto: Jack Digital Productions, 2001.

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34

Anderson, Joseph C., and Charles J. Kahi. Colorectal cancer screening. New York: Humana Press, 2011.

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35

Saltz, Leonard B. Colorectal cancer: Multimodality management. Totowa, N.J: Humana, 2002.

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36

Correia, Mauro Monteiro, Michael A. Choti, Flavio G. Rocha, and Go Wakabayashi, eds. Colorectal Cancer Liver Metastases. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-25486-5.

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37

Scholefield, John H., Axel Grothey, Herand Abcarian, and Tim Maughan, eds. Challenges in Colorectal Cancer. Malden, Massachusetts, USA: Blackwell Publishing Ltd, 2006. http://dx.doi.org/10.1002/9780470753231.

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38

Beauchemin, Nicole, and Jacques Huot, eds. Metastasis of Colorectal Cancer. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-8833-8.

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39

Potter, John D., and Noralane M. Lindor, eds. Genetics of Colorectal Cancer. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-09568-4.

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40

Mike, Makio. Laparoscopic Colorectal Cancer Surgery. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-2320-0.

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41

Cassidy, Jim, Donald Bissett, Roy A. J. Spence OBE, Miranda Payne, Gareth Morris-Stiff, and Amen Sibtain. Colorectal cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199689842.003.0015_update_001.

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Breast cancer reviews the epidemiology and aetiology of this malignancy, with particular attention to the genetics underlying familial breast cancer, its pathology along with its receptors, oestrogen receptor (ER), the growth factor receptor HER2, and epidermal growth factor receptor (EGFR), and the bearing these have on treatment and prognosis. The benefits of breast cancer screening in the population and families at higher risk are discussed. Presenting symptoms and signs are followed by investigation including examination, bilateral mammography, and core biopsy of suspicious lesions. Management of non-invasive in situ disease is considered. Invasive breast cancer is staged according to TNM guidelines. Early breast cancer is defined, managed frequently by breast conserving surgery and sentinel node biopsy from the axilla. A positive sentinel node biopsy requires clearance of the axilla. Larger lesions may require mastectomy. Breast radiotherapy is indicated after breast conserving surgery. Following surgery, the risk of systemic micrometastatic disease is estimated from the primary size, lymph node spread, and tumour grade. Adjuvant chemotherapy improves treatment outcome in all but very good prognosis premenopausal breast cancer, and intermediate or poor prognosis postmenopausal breast cancer. This is combined with trastuzumab in HER2 positive disease. Adjuvant endocrine therapy is recommended for all ER positive breast cancer, tamoxifen in premenopausal, aromatase inhibitors in postmenopausal women. Neoadjuvant chemotherapy may be used in large operable breast cancers to facilitate breast conserving surgery. Locally advanced breast cancer is defined, its high risk of metastatic disease requiring full staging before treatment. Systemic therapy is often best first treatment, according to receptor profile. Metastatic breast cancer although incurable can be controlled for years using endocrine therapy, chemotherapy, trastuzumab, palliative radiotherapy, and bisphosphonates as appropriate. Male breast cancer is uncommon, but management similar.
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42

Welvaart, Kees, L. H. Blumgart, and J. Kreuning. Colorectal Cancer. Springer, 2012.

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43

Cassidy, Jim, Patrick Johnston, and Eric Van Cutsem. Colorectal Cancer. Edited by Jim Cassidy, Patrick Johnston, and Eric Van Cutsem. CRC Press, 2006. http://dx.doi.org/10.3109/9781420016307.

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44

Keum, Nana, Kana Wu, Edward Giovannucci, and David J. Hunter. Colorectal Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190676827.003.0011.

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Colorectal cancer (CRC), typically adenocarcinoma, arises from epithelial cells lining the large bowel or intestine. Colorectal adenomas are well-established precursor lesions for the majority of CRCs. Relatively uncommon prior to 1900, CRC has become the third most commonly diagnosed cancer, as well as the fourth leading cause of malignant death globally. Modifiable causes are demonstrated by the large variation in incidence across countries, rapid changes in incidence within some populations, and the transition in disease risk for immigrants toward that of the host country in migration studies. A number of lifestyle and dietary factors are now established as convincing or probable causes. In addition, the ability to access and remove adenomas can lower cancer incidence through secondary prevention. Thus, a combination of primary and secondary prevention can greatly lower incidence and mortality from CRC.
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45

Bleiberg, Harry, Nancy Kemeny, Phillipe Rougier, and Hansjochen Wilke, eds. Colorectal Cancer. CRC Press, 2001. http://dx.doi.org/10.3109/9780203213650.

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46

Steele, Glenn, Rex, and Sebag-Montefiore. Colorectal Cancer. Not Avail, 2006.

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47

Colorectal cancer. Cambridge: Cambridge University Press, 2007.

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48

McArdle, Colin S., David J. Kerr, and Peter Boyle. Colorectal Cancer. Informa Healthcare, 2000.

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49

ZOFFOUN, Isaac. Cancer Colorectal. Independently Published, 2021.

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50

(Editor), Jim Cassidy, Patrick Johnston (Editor), and Eric Van Cutsem (Editor), eds. Colorectal Cancer. Informa Healthcare, 2006.

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