Relevant bibliographies by topics / Colon (Anatomy) – Cancer – Cytopathology

Academic literature on the topic 'Colon (Anatomy) – Cancer – Cytopathology'

Author: Grafiati
Published: 10 December 2022
Last updated: 29 January 2023

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Journal articles on the topic "Colon (Anatomy) – Cancer – Cytopathology"

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TÜRK, Can. "In silico transcriptomic analysis of ascending colon cancer unearths known and novel genes and gene sets regard to characteristic features of colon cancer." Anatomy 15, no. 1 (2021): 11–25. http://dx.doi.org/10.2399/ana.21.852318.

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Objectives: Colon cancer emerges as a serious health problem in both men and women. Cancers in the colon have different genotypes and phenotypes according to the anatomical region. Tumors in ascending colon are usually diagnosed later, but it is more malignant than the descending and transverse colon, and the survival rates of patients are lower than other regions. The purpose of this study was to determine significantly high or low expressed genes in the ascending colon tumors by comparing all genome information obtained from cancer samples of ascending, transverse and descending colon. In concordance with all this information, another aim of the study was to identify the pathways to which the genes obtained from the colon in the large intestine and to determine their relationship with each other and to correlate them with the characteristics of cancer. Methods: Gene expression values for three subtypes of colon cancer as ascending, transverse, and descending were obtained from GEO (Gene Expression Omnibus) (GSE41258). Data included a total of 47 ascending, 18 transverse and 31 descending colon cancer patient samples. Linear regression analysis was performed to determine differentially expressed genes. Gene Cluster 3.0 was used in order to cluster the genes hierarchically. In addition to linear regression and hierarchical clustering, network analysis with multivariable genes was performed in Cytoscape application 3.8.2 using GeneMANIA. GSEA 4.1.0 (Gene Set Enrichment Analysis) was performed to understand the different genes among the specified groups. Results: As a result of these analyses, it was determined that there were 85 genes with high expression and 139 genes with low expression in the ascending colon tumor samples. It has been shown that these genes can differentiate tumor samples in the ascending colon better than tumor samples in other colon regions. Conclusion: Our findings are important for understanding the genome of ascending colon tumors; if these findings are confirmed in vitro and clinically, it may have potential to be revealed that the identified genes also have biomarker properties for tumors in the ascending colon.
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Henson, Donald E., Matthew T. Hueman, Dechang Chen, Jigar A. Patel, Huan Wang, and Arnold M. Schwartz. "The anatomy of the TNM for colon cancer." Journal of Gastrointestinal Oncology 8, no. 1 (February 2017): 12–19. http://dx.doi.org/10.21037/jgo.2016.11.10.

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Lee, Sang Jae, Sung Chan Park, Min Jung Kim, Dae Kyung Sohn, and Jae Hwan Oh. "Vascular Anatomy in Laparoscopic Colectomy for Right Colon Cancer." Diseases of the Colon & Rectum 59, no. 8 (August 2016): 718–24. http://dx.doi.org/10.1097/dcr.0000000000000636.

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Honarmand, Masoumeh, Fatemeh Namazi, Ali Mohammadi, and Saeed Nazifi. "Can cannabidiol inhibit angiogenesis in colon cancer?" Comparative Clinical Pathology 28, no. 1 (August 27, 2018): 165–72. http://dx.doi.org/10.1007/s00580-018-2810-6.

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Ferreira Portugal, Lorena, Letícia Ribeiro Escocard da Fonseca, Alessandra Oliveira Ferrari Gomes, Maria Auxiliadora Peixoto Peçanha, and Luisa Aguirre Buexm. "RETROSPECTIVE ANALYSIS OF CERVICAL CYTOPATHOLOGICAL EXAMS PERFORMEDAT AT THE LABORATORY OF PATHOLOGICAL ANATOMY AND CYTOPATHOLOGY OF THE HOSPITAL ESCOLA ÁLVARO ALVIM." Revista Científica da Faculdade de Medicina de Campos 16, no. 2 (October 29, 2021): 07–12. http://dx.doi.org/10.29184/1980-7813.rcfmc.537.vol.16.n2.2021.

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Each year about 272,610 new cases of cancer are diagnosed in Brazil, being cervical cancer the third most incident among women. Our country is among those that have made the most progress in consolidating the integrated cancer tracking and surveillance system. This article aims to collect sociodemographic and clinicopathological data from patients who underwent cervical cytopathological examinations at the Laboratory of Pathological Anatomy and Cytopathology at the Hospital Escola Álvaro Alvim (HEAA) from 2014 to 2018, considering a retrospective and longitudinal observation of the data. Sociodemographic and clinicopathological data were collected from 121,044 patients, and it was observed that women from Campos dos Goytacazes (84.7%) over 40 years old (56.8%) were the most prevalent at the service. The following cytological characteristics that predominated in these patients were: absence of atrophy (83.6%) or metaplasia (92.6%) of the uterine epithelium, presence of microorganisms (96.4%) and inflammation (97.2%). The presence of cell atypia (6.5%), squamous intraepithelial lesion (2%) and malignant neoplasm (0.1%) was also observed. Therefore, it becomes possible to highlight the importance of cytological examination in the process of diagnosis of malignant neoplasms of the uterine cervix, being essential for a better control and adequate screening, implementing an effective early diagnosis. It also demonstrates the profile of the patients examined at the Pathological Anatomy and Cytopathology Laboratory of HEAA, as well as the scope of this service for early diagnosis of cervical cancer in the North and Northwest Fluminense.
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Konishi, Tsuyoshi, Yoshifumi Shimada, Lik Hang Lee, Marcela S. Cavalcanti, Meier Hsu, Jesse Joshua Smith, Garrett M. Nash, et al. "Poorly Differentiated Clusters Predict Colon Cancer Recurrence." American Journal of Surgical Pathology 42, no. 6 (June 2018): 705–14. http://dx.doi.org/10.1097/pas.0000000000001059.

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Avizienyte, Egle, Valerie G. Brunton, Valerie J. Fincham, and Margaret C. Frame. "The Src-Induced Mesenchymal State in Late-Stage Colon Cancer Cells." Cells Tissues Organs 179, no. 1-2 (2005): 73–80. http://dx.doi.org/10.1159/000084511.

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Sari, Gando, Triana Retno Putri, Samsun Samsun, Sriyatun Sriyatun, and Nursama Heru Apriantoro. "Loopography Examination For Colon Cancer Cases In Tangerang District Public Hospital." SANITAS: Jurnal Teknologi dan Seni Kesehatan 10, no. 2 (December 27, 2019): 117–27. http://dx.doi.org/10.36525/sanitas.2019.12.

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Loopography examination technique is a radiological examination technique in lower digestive tract (colon) by inserting a positive contrast media into the colon through an artificial hole in abdominal area. This examination aims to evaluate the anatomy and physiology function from distal section of colon to anus with ca colon clinical. This research was conducted in radiology installation of Tangerang District General Hospital during November to December 2018, using a qualitative descriptive method with a literature study approach and interview. The results found that loopography examination in Tangerang District General Hospital did not require special preparation. The kind of contrast media used is a water-soluble contrast media such as iohexol with a ratio of 1: 3 mixed with NaCl. This loopography contrast media can be inserted through the clean stoma or anal. The routine projections performed for loopography examination in Tangerang District General Hospital are Plan photos of Abdomen, Antero Posterior (AP) and Lateral. But sometimes Oblique projection is also used as an addition if is less obvious anatomy due to overlap/superposition.
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Boland, C. R., and J. A. Roberts. "Quantitation of lectin binding sites in human colon mucins by use of peanut and wheat germ agglutinins." Journal of Histochemistry & Cytochemistry 36, no. 10 (October 1988): 1305–7. http://dx.doi.org/10.1177/36.10.3138307.

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We have developed a novel method for quantitation of lectin binding sites in mucins derived from colon tissues. Binding of peanut agglutinin and wheat germ agglutinin was measured in extracts from normal and malignant human colon epithelium. Binding of wheat germ agglutinin was used as an estimate of the total mucin present in the tissue extract. Peanut agglutinin was found to bind to mucin from normal colon, but at levels that may be difficult to appreciate by fluorescence microscopy. The yield of mucin extracted from colon cancer was more variable than that from normal colon, and the binding ratio of peanut agglutinin to wheat germ agglutinin was greater in extracts from tumors than in normal tissues. Our findings confirm the histological observation that peanut agglutinin binds more avidly to mucins from colon cancer than to those from normal colon. The finding of peanut agglutinin binding sites in mucins front normal colon was not expected. The quantitative technique may have detected small numbers of binding sites not readily appreciable by fluorescence microscopy. Alternatively, the chromatographic method for measuring lectin binding may be sufficiently sensitive to detect nonspecific binding of the lectin to terminal galactose residues other than the Thomsen-Friedenreich antigen.
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Manterola, Carlos, and Nataniel Claros. "Results of Surgical Treatment of Uncomplicated Colon Cancer. Case Series with Follow-Up." International Journal of Morphology 39, no. 4 (August 2021): 1171–75. http://dx.doi.org/10.4067/s0717-95022021000401171.

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Dissertations / Theses on the topic "Colon (Anatomy) – Cancer – Cytopathology"

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Wang, Yue. "Exploration of the novel anticancer mechanisms of medicinal compounds involving calpain and S100A4 in the treatment of colon cancer." HKBU Institutional Repository, 2016. http://repository.hkbu.edu.hk/etd_oa/270.

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In summary, this thesis has explored the anti-cancer mechanisms of novel medicinal compounds via targeting calpains or S100A4 in the treatment of colon cancer, which could facilitate future establishment of effective medicinal compounds in the treatment of metastatic colon cancers with known molecular targets.;The incidence of colon cancer in Hong Kong and worldwide is on a rising trend, while its metastatic development is the leading cause of cancer-related deaths. Understanding the molecular mechanisms of how tumors progress and metastasize to secondary sites, at both biological and genetic levels, could enable us to identify potential molecular targets in drug development. In the present study, we explored how manipulation of signaling pathways by targeting calpains and S100A4 could facilitate the development of anti-tumor and anti-metastatic drugs.;The study investigating drug targeting on S100A4 in both in vitro and in vivo models had shown that the pharmacological store-operated calcium channel blocker would suppress S100A4-mediated migration by weakening extracellular S100A4-mediated calcium responses. The effects on S100A4-induced metastasis formation were confirmed in vivo with reduced splenic tumor volume and decreased number of liver metastases. These results have provided new insights to correlate between S100A4 and calcium signaling, making an important step forward in characterizing the dependence of calcium homeostasis in the process of metastasis, providing a novel strategy for S100A4-mediated metastasis.;With respect to the targeting on calpains, it was discovered that total Astragalus saponins (AST) and cryptotanshinone (CPT) are effective anti-cancer agents that elicit the endoplasmic reticulum (ER) stress response. They act by upregulating the expression of glucose-regulated protein (GRP) 78, leading to the initiation of apoptosis when the ER recovery process begins to fail. In particular, CPT caused rapid and sustained increase in cytosolic calcium in colon cancer cells that was accompanied by early GRP78 overexpression. The increase in cytosolic calcium was blocked by pre-treatment of BAPTA-AM through depletion of the ER calcium store. In consistent with these, we also confirmed that CPT significantly increased calpain activity, which could be blocked by calcium chelator or calpain inhibitors. Furthermore, a dynamic interaction between GRP78 and calpain under ER stress was unveiled during AST or CPT exposure. The degree of association was increased following prolonged ER stress, and suppressed either as the ER recovery process failed or with the presence of calpain inhibitors. Besides, inhibition of calpain activity suppressed NF-κB activation (a consequence of ER stress) and substantially enhanced the effects of CPT to promote apoptosis. More importantly, it was confirmed that the effects of calpain inhibitors to sensitize colon cancer cells to ER stress-associated apoptosis are p53-dependent. The anti-tumorigenetic effects of CPT were further demonstrated in vivo in xenografted nude mice by trageting calpains and in combination with calpain inhibitors.
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Pedersen, Katherine Lynn. "Comparison of colorectal cancer screening practices between rural and urban providers." Menomonie, WI : University of Wisconsin--Stout, 2005. http://www.uwstout.edu/lib/thesis/2005/2005pedersenk.pdf.

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Morris, Melinda. "Clinical and pathological predictors of survival for stage II and III colon cancer patients treated with or without chemotherapy : a population-based study." University of Western Australia. School of Surgery and Pathology, 2007. http://theses.library.uwa.edu.au/adt-WU2008.0012.

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[Truncated abstract] Clinical and pathological predictors of survival for stage II and III colon cancer patients treated with or without chemotherapy: a population-based study. Aim: Using a population-based cohort of colorectal cancer (CRC), the major aims of this study were to: 1. Identify clinico-pathological markers that can be used to define a subset of stage II colon cancer patients with excellent prognosis and who therefore do not require referral for adjuvant chemotherapy; 2. Investigate whether there is a survival benefit from the use of adjuvant chemotherapy in a population-based cohort of stage II colon cancer; 3. Investigate stage III colon cancer patients for evidence of predictive markers for response to 5FU chemotherapy; 4. Investigate CRC for age-related differences in clinico-pathological and molecular features. Hypotheses to be tested: 1. A subset of good prognosis stage II colon cancers can be defined using routine pathological markers; 2. Females colon cancer patients gain more survival advantage from 5FU chemotherapy than males; 3. Tumours from young CRC patients have different molecular characteristics to those from older patients; 4. The underlying molecular characteristics of tumour can impact upon the response to 5FU chemotherapy. Methods: The study cohort consisted of 5,971 cases diagnosed between 1993 and 2003 representing over 90% of the CRCs diagnosed in the state of Western Australia. Results: The major findings of this translational research into colon cancer can be summarized as follows: The morphological features of serosal and vascular invasion allow for prognostic stratification of stage II colon cancer into
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Keller, Elizabeth Greer. "Novel chemotherapeutics against lung and colon cancer." Click here for download, 2010. http://proquest.umi.com.ps2.villanova.edu/pqdweb?did=1961333981&sid=1&Fmt=2&clientId=3260&RQT=309&VName=PQD.

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Hou, Wai-kai. "Psychosocial resources and adaptation among Chinese people with colorectal cancer." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B39634346.

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Chan, On-on Annie. "Methylation in colorectal cancer." Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25256312.

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Chan, Tsun-leung. "Genomic instability and DNA mismatch repair gene mutations in colorectal cancer /." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21028874.

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Li, Haitao. "Resveratrol derivatives as colorectal cancer chemopreventive agents." Click to view the E-thesis via HKUTO, 2010. http://sunzi.lib.hku.hk/hkuto/record/B43703720.

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黃冠萍 and Kwun-ping Flora Wong. "A study of MSH2 founder mutation in Hong Kong population." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41712316.

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冼嘉敏. "羽扇豆醇抑制結腸癌細胞生長初步機理研究." HKBU Institutional Repository, 2011. http://repository.hkbu.edu.hk/etd_ra/1324.

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Books on the topic "Colon (Anatomy) – Cancer – Cytopathology"

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Colon cancer. Detroit: Lucent Books, 2012.

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M, Lynch Patrick, and Lynch Henry T, eds. Colon cancer genetics. New York: Van Nostrand Reinhold Co., 1985.

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Fisher, Stephen J. Colon cancer & the polyps connection. Tuscon, Ariz: Fisher Books, 1995.

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1935-, Skarin Arthur T., and Saunders Mark, eds. Colorectal cancer. Edinburgh: Elsevier, 2007.

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Colorectal cancer. Berlin: Springer, 2002.

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Beauchemin, Nicole, and Jacques Huot. Metastasis of colorectal cancer. Dordrecht: Springer, 2010.

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Colorectal cancer. Philadelphia: Saunders/Elsevier, 2010.

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Ahuja, Nita. Patients' guide to colon and rectal cancer. Burlington, MA: Jones & Bartlett Learning, 2014.

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Jenkins, Julianne E. Colorectal cancer: Risk, diagnosis, and treatments. New York: Nova Science Publishers, 2011.

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Rosenthal, M. Sara. 50 ways to prevent colon cancer. Los Angeles: Lowell House, 2000.

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Book chapters on the topic "Colon (Anatomy) – Cancer – Cytopathology"

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Salimoglu, Semra, Gizem Kilinc, and Bulent Calik. "Anatomy of the Colon, Rectum, and Anus." In Colon Polyps and Colorectal Cancer, 1–22. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-57273-0_1.

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Akpinar, Goksever, and Alper Uguz. "Surgical Anatomy of the Liver and Biliary Tree." In Colon Polyps and Colorectal Cancer, 529–51. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-57273-0_26.

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Dumlu, Ersin Gurkan, Mehmet Tokac, and Derya Karakoc. "Colorectal Embryology and Anatomy." In Colon Polyps and the Prevention of Colorectal Cancer, 1–12. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17993-3_1.

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Bertelsen, C. A., and Danilo Miskovic. "Surgical Anatomy of the Colon and Complete Mesocolic Excision." In Multidisciplinary Treatment of Colorectal Cancer, 141–55. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-58846-5_16.

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Seiden, David L., and Siobhan Corbett. "Colon Cancer." In Lachman's Case Studies in Anatomy, 296–304. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199846085.003.0036.

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SHAMSUDDIN, ABULKALAM M. "Normal and Pathological Anatomy of the Large Intestine." In Colon Cancer Cells, 15–40. Elsevier, 1990. http://dx.doi.org/10.1016/b978-0-12-509375-0.50007-0.

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Willaert, Wouter. "Anatomy and embryology of the lymphatic system of the colon and rectum." In The Lymphatic System in Colorectal Cancer, 57–72. Elsevier, 2022. http://dx.doi.org/10.1016/b978-0-12-824297-1.00005-1.

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"Pathology." In Oxford Handbook for Medical School, edited by Kapil Sugand, Miriam Berry, Imran Yusuf, Aisha Janjua, Chris Bird, David Metcalfe, Harveer Dev, et al., 557–66. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780199681907.003.0028.

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Pathology is the scientific study of disease, while clinical pathology is about integrating the morphological, biochemical, and molecular analyses with the clinical information provided to achieve a definite diagnosis. Its major subdivisions include histopathology, cytopathology, haematopathology, chemical pathology, and medical microbiology. Other disciplines include medical genetics, immunology, virology, toxicology, and forensic pathology. Histopathology involves studying tissue, such as biopsy specimens, to make a diagnosis, most commonly in the diagnosis of cancer and the chapter discusses grading and staging of cancers. The chapter also covers UK screening programmes for cervical, breast, and colon cancer. Haematological, skin, and cell specimens are also discussed, alongside other methods such as immunohistochemistry and immunofluorescence. Forensic pathology and criteria for referring a death to the coroner are also covered.
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Marilyn, Weaver Lewis, Wu Liyun, and Allan Hagen Zachary. "How Understanding the Gastrointestinal System Can Benefit Mental Health Clinicians." In STEM-H for Mental Health Clinicians, 151—C10P35. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/oso/9780197638514.003.0010.

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Abstract STEM-H for Mental Health Clinicians, Chapter 10, introduces clinicians to the basic anatomy and physiology of the gastrointestinal (GI) system. The signature illnesses discussed are irritable bowel syndrome, colon cancer, and obesity. Cleft lip and palate are included as signature injuries. Technologies that provide enteral feedings using gastric or jejunal tubes are introduced. Other technologies include gastric surgeries that treat obesity. Engineering of medications prescribed for obesity are explained in terms of neurotransmission. Mathematical data show empirical evidence of the prevalence of obesity, social determinants of health, and Type 2 diabetes. Disease burden is introduced as a concept to explain impact of obesity on individuals and society. Mindfulness is presented as an intervention that clinicians can teach clients who suffer from GI disorders.
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Conference papers on the topic "Colon (Anatomy) – Cancer – Cytopathology"

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Tandon, S., S. Mitra, M. K. Sharma, U. Saxena, P. Ahlawat, I. Kaur, A. Chowdhary, and P. Surkar. "Image guided interstitial brachytherapy for locally advanced disease after external beam radiotherapy in a case of carcinoma cervix – our institutional experience." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685276.

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Purpose/Objective: Cervical cancer is the third most common cancer in women worldwide. Definitive chemoradiation is the accepted standard of care for patients especially for locally advanced cervical cancers. Intracavitary brachytherapy (ICBT) is an important part of definitive radiotherapy shown to improve overall survival. Interstitial brachytherapy (ISBT) is generally reserved for patients either with extensive pelvic and/or vaginal residual disease after external beam radiotherapy (EBRT) or with anatomy not allowing ICBT with standard applicators in an attempt to improve local control. We have conducted an observational study for patients who underwent image guided HDR-ISBT at our institute. Materials and Methods: Seven patients; diagnosed as a case of carcinoma cervix; were selected from the period of 2012 to 2015 who received EBRT by IMRT and for whom ICBT couldn’t be done for various reasons. These patients were then taken up for Martinez Universal Perineal Interstitial Template (MUPIT) image based ISBT. A descriptive analysis was done for doses received by HRCTV, bladder, rectum and sigmoid colon. At the end of treatment, early response at 3 months along with overall survival (OS) and disease free survival (DFS) was also calculated. Results: All the patients recruited were locally advanced with 3 patients in IIB, 1 patient in IIIA and 3 patients belonging to IIIB. The mean dose received by 95% high risk CTV (HRCTV) by IMRT was 49.75 Gy. Out of 7 patients, 3 were taken up for ISBT due to anatomical restriction whereas remaining 4 patients were included because of lack of dose coverage by ICBT. The mean doses received by 90% of HRCTV, 2 cc bladder, 2 cc rectum and 2 cc sigmoid colon were 20.58 Gy, 2.73 Gy, 3.19 Gy and 2.82 Gy respectively. The early response at 3 months was 57.14%. The DFS at one year and OS at 3 year were 53.6% and 53.3% respectively. Conclusions: Our descriptive analysis of seven patients being treated by image based ISBT have revealed that locally advanced cervical cancer patients for whom ICBT is unsuitable can achieve equitable LRC and OS with a combination of EBRT by IMRT and image based HDR-ISBT.
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