Journal articles on the topic 'Colombia. 1902 November 21'

On 21 July 1904, just over 80 years ago, the barque-rigged, Norwegian-built auxiliary steamship Scotia sailed home up the Clyde with members of the Scottish National Antarctic Expedition (SNAE), concluding one of the most successful expeditions of the heroic period of Antarctic exploration. Contemporaneous with the more spectacular British Antarctic Expedition (1901–03) commanded by Robert Falcon Scott, the Scotia party under William Spiers Bruce had overwintered on Laurie Island (60° 44ʹ S, 44° 50ʹ W) in the South Orkney Islands, explored for the first time the oceanography of the Weddell Sea, assembled an important collection of scientific material, and discovered Coats Land, an icebound stretch of the East Antarctica coast.While Scott's Discovery expedition had emphasized geographical exploration inland from the Ross Sea sector of Antarctica, Bruce in the Scotia had concentrated more on scientific discovery in the Weddell Sea sector. On 12 November 1904 in Edinburgh, members of the Scotia and Discovery expeditions were guests at the 20th anniversary dinner of the Royal Scottish Geographical Society, Bruce and Scott together responding to a presidential toast that honoured the success of both.

On November 27, 1902 Colombia signed an agreement with the Vatican that established parameters for the evolution of the mission as a frontier institution in the twentieth century. Renewed in 1928 and again in 1953, the Convenio sobre Misiones granted to religious orders chosen by the Vatican absolute authority to govern, police, educate, and control the Indians in the peripheral regions of the republic, which at that time accounted for sixty-five percent of the national domain but only two percent of the population. An exchange for substantial state subsidies, the orders were to carry out such government functions as administering a rudimentary judicial apparatus, providing primary education for whites as well as Indians, and promoting colonization through unlimited access to public lands. Another provision assured the ascendancy of the religious over civilian authorities by granting the former the right to reject nominees for positions in civil government if they regarded the candidates as unsuitable or as threatening to the Indians or the missionaries. Under these terms, the Augustinian Recoletos (Candelarios) in Casanare and the Capuchins in Putumayo expanded their operations, while between 1903 and 1918 the Montfort Fathers, Lazarists, Claretians, Carmelites, and Jesuits took control of apostolic prefectures and vicariates in other parts of the country.

Social entrepreneurship has an increasingly important role in the solution of current social challenges. The aim of this document is to establish an articulation strategy to strengthen the management of social entrepreneurship projects in a region of southern Colombia. A mixed study was carried out by collecting and analyzing qualitative and quantitative data. Actors of the social entrepreneurship ecosystem was studied. Surveys were applied to social entrepreneurs, interviews and focus groups with experts in entrepreneurship from the academic, public and private sectors were carried out. The level of development of the social entrepreneurship ecosystem was identified through the collection of primary sources. Finally, strategies were designed to strengthen the projects of this ecosystem. The strategies focused on the ecosystem community, an enabling environment, the interconnection of the Ecosystem, Entrepreneurial Development Programs, Education, and a city-wide entrepreneurial strategy. Received: 21 August 2022 / Accepted: 11 October 2022 / Published: 5 November 2022

Purpose : To perform a prevalence study of Punctate Keratopathy of West Indians in Colombian individuals and to propose a new name for the condition. Methods : Prospective, population-based epidemiological study. All patients evaluated between November 1 and December 31, 2012, in the Centro Oftalmológico Virgilio Galvis and Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, Colombia, with clinical findings of white corneal opacities corresponding to Punctate Keratopathy of West Indians were identified. Careful slit-lamp examination was performed for clinical diagnosis and findings were reported in the electronic medical record indicating number and location of the lesions. Prevalence was calculated for the total population, and for gender and age groups. Furthermore a literature review was performed and a new name for the condition proposed. Results : In the whole group of patients, prevalence was 1.0%. No one case was diagnosed in a patient younger than 21 year-old. No one lesion was located within 2.5 mm of the corneal apex. 96% of affected patients had unilateral involvement. 58.5% of eyes had a single corneal lesion; 7% of eyes had 6 or 7 corneal lesions. Conclusion : The condition heretofore known as Punctate Keratopathy of West Indians was present in 1% of our patients in Colombia (South America). Thus, this non-infectious, non-inflammatory, asymptomatic ailment of unknown etiology is not restricted to people of Antillean descent, or who have lived in these islands. We propose the new name “Rice's keratopathy". Age and male gender were independent risk factors for the presence of the keratopathy.

Waste Electrical and Electronic Equipment (WEEE) management presents profound environmental challenges worldwide. In locales like Huila, Colombia, devising effective strategies is paramount for fostering sustainable trajectories. This investigation aims to identify the salient elements essential for developing a proficient approach to WEEE management in this region. Employing a predominantly qualitative mixed-methods approach, the study intertwines inductive, deductive, and abductive rationales, applying an interpretative perspective. Our sample encompassed 72 stakeholders active in WEEE management, extending from urban households to WEEE-focused businesses and environmental entities. Comprehensive questionnaires gathered data on socio-demographics, WEEE awareness, comprehension of relevant regulations, and associated practices. An exhaustive descriptive statistical analysis examined each variable's behavior, supplemented by visual representations and pivotal statistical parameters. These findings were further augmented by a SWOT analysis. Results emphasize the cardinal challenges in sculpting a strategic WEEE management pathway, yielding insights indispensable for policymakers intent on refining WEEE procedures. Moreover, the investigation introduces a methodical framework for secure, effective electronic waste handling, transportation, precious metal extraction, and disposal. Fundamentally, this research enriches the discourse on WEEE management, proffering pragmatic solutions with extensive ramifications. Received: 15 August 2023 / Accepted: 21 October 2023 / Published: 5 November 2023

The Russian military invasion of Ukraine on February 24, 2022, and Hamas’ terror attack on Israel on October 7, 2023, signaled the beginning of two of the most recent wars to make international headlines. To date, over 110 armed conflicts are taking place: over 45 in the Middle East and North Africa (Cyprus, Egypt, Iraq, Israel, Libya, Morocco, Palestine, Syria, Turkey, Yemen, Western Sahara); over 35 in Africa (Burkina Faso, Cameroon, the Central African Republic, the Democratic Republic of the Congo, Ethiopia, Mali, Mozambique, Nigeria, Senegal, Somalia, South Sudan, Sudan); 21 in Asia (Afghanistan, India, Myanmar, Pakistan, the Philippines); seven in Europe (Russia, Ukraine, Moldova, Georgia, Armenia, Azerbaijan); and six in Latin America (three each in Mexico and Colombia); with two more international armed conflicts (between India and Pakistan, and between India and China) in Asia.1 This list does not even include such problematic situations as those involving China and the South East Asia region. As though these situations of armed violence were not enough, mankind has already passed or is on the verge of passing several climate tipping points – a recent review lists nine Global core tipping elements (and their tipping points) - the Greenland Ice Sheet (collapse); West Antarctic Ice Sheet (collapse); Labrador-Irminger Seas / SPG Convection (collapse); East Antarctic Subglacial Basins (collapse); Amazon Rainforest (dieback); Boreal Permafrost (collapse); Atlantic M.O. Circulation (collapse); Arctic Winter Sea Ice (collapse); and East Antarctic Ice Sheet (collapse); and seven Regional impact tipping elements (and their tipping points) – Low-latitude Coral Reefs (die-off); Boreal Permafrost (abrupt thaw); Barents Sea Ice (abrupt loss); Mountain Glaciers (loss); Sahel and W. African Monsoon (greening); Boreal Forest (southern dieback); and Boreal Forest (northern expansion).2 Closer to home, how can we forget the disaster and devastation wrought by Super Typhoon Haiyan (Yolanda) 10 years ago to date? Whether international or non-international, armed conflicts raise the risk of nuclear war. Russia has already “rehearsed its ability to deliver a ‘massive’ nuclear strike,” conducting “practical launches of ballistic and cruise missiles,” and stationed a first batch of tactical nuclear weapons in Belarus,3 and the possibility of nuclear escalation in Ukraine cannot be overestimated.4 Meanwhile, in a rare public announcement, the U.S. Central Command revealed that an Ohio- class submarine (560 feet long, 18,750 tons submerged and carrying as many as 154 Tomahawk cruise missiles) had arrived in the Middle East on November 5, 2023.5 Indeed, “the danger is great and growing,” as “any use of nuclear weapons would be catastrophic for humanity.”6

BackgroundOver the last two decades, our knowledge of spondyloarthritis (SpA) has been improved. The awareness of this disease within the medical community and the implementation of advances in clinical practice are unclear, especially in some geographical regions less well represented in research studies.ObjectivesThe aim of our study was to evaluate the changes overtime in disease profile in patients with SpA from a Colombian cohort.MethodsData from 471 patients recruited in a prospective Colombian cohort of Spondyloarthritis patients (diagnosed according to rheumatologist), with registries from 90’ to the date was analyzed. Three time periods were stablished for the analysis, the first period from the first registry until October 10, 2003; the second period from October 10, 2003 to October 26, 2010; and the third period from October 26, 2010 to December 31, 2021. The patients were reclassified according to ASAS classification using the information available, and judgment from a group of four expert rheumatologists.Results471 patients were included in the study, period 1 (n = 158), period 2 (n = 150) and period 3 (n = 163). There were no differences in sex distribution across three periods. Time to diagnosis was shorter in period 1 than 3 (table 1).The frequency of r-AxSpA diagnosis was proportionally higher in period 1 (47.5%), than period 2 (38.2%), and 3 (31.3%), P = 0.013. For another hand, the frequency of nr-AxSpA diagnosis was lower in the period 1 (9.5%) than period 2 (15.1%), and 3 (22.1%) (view graphic). The frequency of peripheral SpA diagnosis was similar across the three periods (38% vs. 39.5% vs. 37.4%, for periods 1, 2 and 3 respectively, P = 0.8). The presence of dactylitis at physical examination was most common in the first period (10.8%) than the last two periods (3.3% and 3.7%), P = 0.007. There were no differences in frequency of dactylitis, arthritis or uveitis.There were no statistically significant differences in frequency of HLA-B27 (42.4% vs. 44.8% vs. 48.6%, for periods 1, 2 and 3, respectively, P = 0.2) or HLA-B15 (14.4% vs. 8.2% vs. 15%, for periods 1, 2 and 3, respectively, P = 0.2) across the three periods. The metrology analysis showed higher physical limitation in the first period (thoracic expansion < 2.5 cms and modified Schober < 5 cms) than in the last two period (view table 1).The history of psoriasis in SpA patients was higher in period 1 (7.6%) than period 2 (2.6%), and 3 (2.5%), P = 0.036. Infections preceding SpA symptoms onset were most frequent in period 1 (32.9%) than period 2 (29.6%) and 3 (16.6%), P = 0.002.ConclusionThe profile of patients with SpA has evolved over time in Colombia. While the frequency of peripheral SpA has remained unchanged over time, the incidence of non-radiographic axial forms has increased over time. Furthermore, functional limitation in SpA, infections preceding symptoms, and dactylitis are less common than 20 years ago. These results highlight the impact of advances in rheumatology and the awareness of the medical community about this disease in Colombia, allowing an earlier diagnosis or the diagnosis of less evident forms of SpA.Table 1.Variable< November 11, 2003November 11, 2003 – October 26, 2010> October 26, 2010P valueTotal158150163Female57 (36.1%)47 (30.9%)59 (36.2%)0.5Time to diagnosis (months)12 (3 – 40.5)18 (3 – 62)49.5 (9.75 – 122)0.00ASAS axial91 (57.6%)82 (53.9%)85 (52.1%)0.4ASAS peripheral60 (38%)60 (39.5%)61 (37.4%)0.4HLA-B2759 (42.4%)60 (44.8%)68 (486%)0.22HLA-B1520 (14.4%)11 (8.2%)21 (15%)0.22VAS spinal pain6 (3 - 8)5 (3 - 8)6 (2 - 8)0.86Disease activity by patient6.5 (4.5 - 8.5)6 (5 - 8)6 (4- 8)0.55Occiput to wall distance0 (0 - 0)0 (0 - 0)1 (0 - 3)0.00Right lateral flexion test10 (3 - 19.75)15 (10.38 - 19)14 (10 - 17)0.01Left lateral flexion test13 (3 - 20)15-75 (11 - 18.25)14 (11 - 17)0.05Limited thoracic expansion (< 2.5 cms)28 (17.7%)15 (10.5%)16 (9.9%)0.02Limited lumbar Schober (< 5)103 (71%)90 (62.1%)85 (53.1%)0.01Graphic 1.Three periods P value < 0.05rx-axSpA: radiographic axial Spondyloarthritis; nr-AxSpA: non-radiographic axial Spondyloarthritis.REFERENCES:NIL.Acknowledgements:NIL.Disclosure of InterestsNone Declared.

The World Trade Center Attack or 9/11 tragedy has awakened the international community, particularly the United States (US) to sharpen its foreign policy in facing security threats coming from ‘weak states’. One of the most prominent weak states examples that pose a grave threat to other countries are the Northern Triangle Countries of Central America that referred to Guatemala, Honduras, and El Salvador. Hence, this paper will discuss the rationale behind US initiatives in dealing with security threats in El Salvador as one of the Northern Triangle Countries. In analyzing the case, the writers will use the weak state concept and national interest concept. The result of this paper finds that El Salvador corresponds to the elements of a weak state and further poses security threats by giving rise to transnational criminal organizations, drug trafficking, and migrant problems in which overcoming those security threats has become US vital national interest. However, we also find that although decreasing security threats and strengthening El Salvador government capacity is highly correlated, strengthening El Salvador governance through the providence of aid and assistance is actually classified as US important national interest. Keywords: Security threats; Northern Triangle; weak state; El Salvador; national interest REFERENCES Ambrus, Steven. “Guatemala: The Crisis of Rule of Law and a Weak Party System.” Ideas Matter, January 28, 2019. https://blogs.iadb.org/ideas-matter/en/guatemala-the-crisis-of-rule-of-law-and-a-weak-party-system/. Andrade, Laura. Transparency In El Salvador. 1st ed. 1. El Salvador: University Institute for Public Opinion, Asmann, Parker. “El Salvador Citizens Say Gangs, Not Government 'Rule' the Country.” InSight Crime, August 19, 2020. https://insightcrime.org/news/brief/el-salvador-citizens-say-gangs-not- government-rules-country/. Accessed July 11, 2021. Art, Robert J. A. Grand Strategy for America. Ithaca: Century Foundation/Cornell UP, 2004. BBC News Indonesia "Kisah Di Balik MS-13, Salah Satu Geng Jalanan Paling Brutal Di Dunia." BBC News Indonesia. BBC, April 21, 2017.https://www.bbc.com/indonesia/majalah-39663817.Accessed July 11, 2021. Bureau of Western Hemisphere Affairs “U.S. Relations With El Salvador - United States Department of State.” U.S. Department of State. U.S. Department of State, April 14, 2021.https://www.state.gov/u-s-relations-with-el-salvador/. Accessed July 11, 2021. “Bureau of International Narcotics and Law ENFORCEMENT Affairs: El Salvador Summary -United States Department of State.” U.S. Department of State. U.S. Department of State, February3, 2021. https://www.state.gov/bureau-of-international-narcotics-and-law-enforcement-affairs-work-by-country/el-salvador-summary/. Central Intelligence Agency. Central Intelligence Agency, July 6, 2021. https://www.cia.gov/the-world-factbook/countries/el-salvador/. Accessed July 11, 2021. Dudley, Steven, and Avalos, Silva “MS13 In the Americas: How the World’s Most Notorious Gang Defies Logic, Resists Destruction. National Institute of Justice”, 2018. “El Salvador Homicides Jump 56 Percent as Gang Truce Unravels.” Reuters, December 30,2014.https://www.reuters.com/article/us-el-salvador-violence-idUSKBN0K81HR20141230. Eizenstat, Stuart E., John Edward Porter, and Jeremy M. Weinstein. “Rebuilding Weak States.”Foreign Affairs 84, no. 1 (2005): 134. https://doi.org/10.2307/20034213. FOXBusiness. “How MS-13, One of America's Most Dangerous Gangs, Is Funded.” Fox Business.Fox Business, April 19, 2017.https://www.foxbusiness.com/features/how-ms-13-one-of-americas-most-dangerous-gangs-is-funded. Accessed July 11, 2021. Fukuyama, Francis.Cornell University Press. Ithaca, USA: Cornell University Press, 2004. Galdamez, Eddie. “Water Pollution in El Salvador. Getting Worse Every Year.” El Salvador INFO,June 30, 2021. https://elsalvadorinfo.net/water-pollution-in-el-salvador/. Accessed July 11, 2021. Gies, Heather. “Once Lush, El Salvador Is Dangerously Close to Running out of Water.” Environment. National Geographic, May 4, 2021.https://www.nationalgeographic.com/environment/article/el-salvador-water-crisis-drought-climate-change. Accessed July 11, 2021. Giedraityte, Ieva. “Empire, Leadership OR Hegemony: US Strategies towards the Northern Triangle Countries in the 21st Century.” Latin American Yearbook – Political Science and International Relations 7 (2019): 175. https://doi.org/10.17951/al.2019.7.175-192. “Government Revenues.” Government Revenues - Countries - List. Accessed August 4, 2021.https://tradingeconomics.com/country-list/government-revenues. “Guatemala: An Assessment of Poverty.” Poverty Analysis - Guatemala: An Assessment of Poverty. Accessed August 4, 2021. https://web.archive.org/web/20161225194831/http://web.worldbank.org/WBSITE/EXTERNAL/ TOPICS/EXTPOVERTY/EXTPA/0,,contentMDK:20207581~menuPK:443285~pagePK:148956~piPK:216618~theSitePK:430367,00.html. Herningtyas, Ratih. "Weak State As A Security Threat: A Case Study Of Colombia." Journal of International Relations 2, no. 2 (2014): 146-156. “Honduras.” World Bank. Accessed August 4, 2021. https://www.worldbank.org/en/country/honduras#:~:text=Honduras%20is%20a%20low%20middle,than%20US%241.90%20per%20day. Iesue, Laura. “The Alliance for Prosperity Plan: A Failed Effort for Stemming Migration,” COHA, November 21, 2019, https://www.coha.org/the-alliance-for-prosperity-plan-a-failed-effort-for-stemming-migration/. Accessed July 11, 2021 Indexmundi. “Countries Ranked by Intentional Homicides (per 100,000 People)." Countries ranked by Intentional homicides (per 100,000 people), n.d.,https://www.indexmundi.com/facts/indicators/VC.IHR.PSRC.P5/rankings. Accessed July 11,2021. Insight Crime. “Central America Regional Security Initiative (CARSI)." InSight Crime, October 18,2011, https://insightcrime.org/uncategorized/central-america-regional-security-initiative/. Accessed July 11, 2021 “Income Held by Top 20 Percent in El Salvador.” Statista, July 5, 2021.https://www.statista.com/statistics/1075313/el-salvador-income-inequality/. International Monetary Fund. “El Salvador: Selected Issues.” IMF Staff Country Reports 16, no. 206 (2016): 1. https://doi.org/10.5089/9781498342346.002. Interpol "El Salvador." El Salvador, n.d.,https://www.interpol.int/en/Who-we-are/Member-countries/Americas/EL-SALVADOR. Accessed July 11, 2021. “Key Issues AFFECTING Youth in El Salvador - OCDE.” Key Issues affecting Youth in El Salvador - OCDE. Accessed August 8, 2021.https://www.oecd.org/fr/pays/elsalvador/youth-issues-in-el-salvador.htm. Lakhani, Nina. “Gang Violence in El Salvador Fuelling Country's Child Migration Crisis.” The Guardian. Guardian News and Media, November 18, 2014.https://www.theguardian.com/world/2014/nov/18/el-salvador-gang-violence-child-migration-crisis. Accessed July 11, 2021. “Life under Gang Rule in El Salvador.” Crisis Group, December 10, 2018. https://www.crisisgroup.org/latin-america-caribbean/central-america/el-salvador/life-under-gang-rule-el-salvador. Löwenheim, Oded. “Transnational Criminal Organizations and Security: The Case against Inflating the Threat.” International Journal 57, no. 4 (2002): 513–36. https://doi.org/10.2307/40203690. “Mano Dura: El Salvador Responds to Gangs.” Taylor & Francis. Accessed August 5, 2021.https://www.tandfonline.com/doi/abs/10.1080/09614520701628121?journalCode=cdip20.Menjivar, Cecilia, and Andrea Gomez Cervates. “El Salvador: Civil War, Natural Disasters, and Gang Violence Drive Migration.” migrationpolicy.org, May 11, 2021.https://www.migrationpolicy.org/article/el-salvador-civil-war-natural-disasters-and-gang-violence-drive-migration. Accessed July 11, 2021. Meyer, Peter J., and Ribando Clare Seelke. Central America Regional Security Initiative: Background and Policy Issues for Congress. Washington, D.C.: Library of Congress, Congressional Research Service, 2014. Michaels, Peter S. Lawless Intervention: United States Foreign Policy in El Salvador and Nicaragua, 6, 7, no. 2 (January 5, 1987). https://doi.org/https://core.ac.uk/download/pdf/71463263.pdf. OSAC. “El Salvador 2020 Crime & Safety Report,” https://www.osac.gov/Content/Report/b4884604- 977e-49c7-9e4a-1855725d032e. Days on July 9, 2021. “Overview.” World Bank. Accessed August 4, 2021. https://www.worldbank.org/en/country/elsalvador/overview. Patrick, Stewart. “Weak States and Global Threats: Assessing Evidence of Spillovers.” SSRN Electronic Journal, 2006, 1–31. https://doi.org/10.2139/ssrn.984057. Published by Teresa Romero, and Jul 5. “Gini Coefficient: Wealth Inequality in El Salvador.” Statista,July 5, 2021.https://www.statista.com/statistics/983230/income-distribution-gini-coefficient-el-salvador/. “Remarks by President Obama after Meeting with Central American Presidents.” National Archives and Records Administration. National Archives and Records Administration. Accessed August 8, 2021. https://obamawhitehouse.archives.gov/the-press-office/2014/07/25/remarks-president-obama-after-meeting-central-american-presidents. Riney, Lt Col Thomas J. “How Is MS-13 a Threat to US National Security? .” AIR WAR COLLEGE AIR UNIVERSITY , February 12, 2009. https://apps.dtic.mil/sti/pdfs/ADA540139.pdf. Rivera, Mauricio. “Drugs, Crime, and NONSTATE Actors in Latin America: Latin American Politics and Society.” Cambridge Core. Cambridge University Press, October 12, 2020. https://www.cambridge.org/core/journals/latin-american-politics-and-society/article/abs/drugs-crime-and-nonstate-actors-in-latin-america/67CF0B66AB8673D0C50F2F99AC93A1B7. Schneider, Mark. “Where Are the Northern Triangle Countries Headed? And What Is U.S. Policy?” Center for Strategic and International Studies (CSIS), July 9, 2021. https://www.csis.org/analysis/where-are-northern-triangle-countries-headed-and-what-us-policy. Seelke, Clare Ribando. “CRS Report for Congress.” El Salvador: Political, Economic, and Social Conditions and U.S. Relations, November 18, 2008. https://doi.org/https://www.refworld.org/pdfid/4951ec75e.pdf. Silva Avalos, Hector. “Corruption in El Salvador: Politicians, Police, and Transportistas.” SSRN, April 2, 2014. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2419174. Sleinan, Julett Pineda. “Salvadoran Court: Ex-President and Wife Guilty of Illicit Enrichment.” OCCRP. Accessed August 5, 2021. https://www.occrp.org/en/daily/13586-salvadoran-court-ex- president-and-wife-guilty-of-illicit-enrichment. The United States Department of Justice. “MS-13's Highest-Ranking Leaders Charged with Terrorism Offenses in the United States.”, January 19, 2021. https://www.justice.gov/opa/pr/ms-13-s-highest-ranking-leaders-charged-terrorism-offenses-united-states. Retrieved July 9, 2021. Transformation Index. “BTI 2020 El Salvador Country Report.” BTI Blog, 2020. https://www.bti-project.org/en/reports/country-report-SLV.html. Accessed July 11, 2021. “U.S. Strategy for Engagement in Central America Results Architecture – Overall Summary.”State.gov. Accessed August 8, 2021. https://www.state.gov/wp-content/uploads/2019/04/U.S.-Central-America-Strategy-Objectives.pdf. United Nations High Commissioner for Refugees. “Death Threats and Gang Violence Forcing More Families to FLEE Northern Central America – UNHCR and Unicef Survey.” UNHCR. Accessed August 5, 2021. https://www.unhcr.org/news/press/2020/12/5fdb14ff4/death-threats-gang-violence-forcing-families-flee-northern-central-america.html. U.S. Department of Homeland Security, “Combating Gangs,” https://www.ice.gov/features/gangs.Diakses pada 9 Juli 2021. USAID, “GENERATING HOPE: USAID IN EL SALVADOR, GUATEMALA, AND HONDURAS,”https://www.usaid.gov/generating-hope-usaid-el-salvador-guatemala-and honduras. Diakses pada 8 Juli 2021. United States General Accounting Office, “EL SALVADOR Military Assistance Has Helped Counter but Not Overcome the Insurgency,” https://www.gao.gov/assets/nsiad-91-166.pdf. Retrieved July 8, 2021. U.S. Immigration and Customs Enforcement “Combating Gangs.”, January 27, 2021. https://www.ice.gov/features/gangs. Accessed July 9, 2021. Valencia, Robert. “MS-13 and Barrio 18 Gangs Allegedly Employ More People in El Salvador than the Country's Largest Employers.” Newsweek. Newsweek, November 2, 2018.https://www.newsweek.com/ms-13-barrio-18-gangs-employ-more-people-el-salvador-largest-employers-1200029. Accessed July 11, 2021 Wang, Shaoguang. "China's Changing of the Guard: The Problem of State Weakness." Journal of Democracy 14, no. 1 (2003): 36-42. doi:10.1353/jod.2003.0022. Weber, Max. “Economy and society: An outline of interpretive sociology. Vol. 1. Univ of California Press, 1978. Welsh, Teresa. “US to Resume Northern Triangle Aid, Pompeo Says.” devex, 2019.https://www.devex.com/news/us-to-resume-northern-triangle-aid-pompeo-says-95846. Whelan, Robbie. “Why Are People Fleeing Central America? A New Breed of Gangs Is Taking Over.” The Wall Street Journal. Dow Jones & Company, November 2, 2018. https://www.wsj.com/articles/pay-or-die-extortion-economy-drives-latin-americas-murder-crisis-1541167619. Retrieved July 8, 2021. Williams, Phil. "Transnational criminal enterprises, conflict, and instability." Turbulent Peace: The challenges of managing international conflict (2001): 97-112. World Bank. “Overview.” World Bank, October 9, 2020.https://www.worldbank.org/en/country/elsalvador/overview. Retrieved July 8, 2021.

Canon and oblivion. The memorials of archaeologyThe article takes its point of departure in the sun chariot; the find itself and its find site at Trundholm bog where it was discovered in 1902. The famous sun chariot, now at the National Museum in Copenhagen, is a national treasure included in the Danish “Cultural Canon” and “History Canon”.The find site itself has alternated bet­ween experiencing intense attention and oblivion. A monument was erected in 1925; a new monument was then created in 1962 and later moved in 2002. The event of 1962 was followed by ceremonies, speeches and songs, and anniversary celebrations were held in 2002, during which a copy of the sun chariot was sacrificed.The memorial at Trundholm bog is only one of several memorials at archaeological find sites in Denmark. Which finds have been commemorated and marked by memorials? When did this happen? Who took the initiative? How were they executed? Why are these finds remembered? What picture of the past do we meet in this canon in stone?Find sites and archaeological memorials have been neglected in archaeology and by recent trends in the study of the history of archaeology. Considering the impressive research on monuments and monumentality in archaeology, this is astonishing. However, memorials in general receive attention in an active research field on the use of history and heritage studies, where historians and ethnologists dominate. The main focus here is, however, on war memorials. An important source of inspiration has been provided by a project led by the French historian Pierre Nora who claims that memorial sites are established when the living memory is threatened (a thesis refuted by the many Danish “Reunion” monuments erected even before the day of reunification in 1920).Translated into Danish conditions, studies of the culture of remembrance and memorials have focused on the wars of 1848-50 and 1864, the Reunion in 1920, the Occupation in 1940-45 and, more generally, on conflicts in the borderland bet­ween Denmark and Germany.In relation to the total number of memorials and public meeting places in Denmark, archaeological memorials of archaeology are few in number, around 1 % of the total. However, they prompt crucial questions concerning the use of the past, on canon and oblivion.“Canon” means rule, and canonical texts are the supposed genuine texts in the Bible. The concept of canon became a topic in the 1990s when Harold Bloom, in “The Western Canon”, identified a number of books as being canonical. In Denmark, canon has been a great issue in recent years with the appearance of the “Danish Literary Canon” in 2004, and the “Cultural Canon” and the “History Canon”, both in 2006. The latter includes the Ertebølle culture, the sun chariot and the Jelling stone. The political context for the creation of canon lists is the so-called “cultural conflict” and the debate concerning immigration and “foreigners”.Canon and canonization means a struggle against relativism and oblivion. Canon means that something ought to be remembered while something else is allowed to be forgotten. Canon lists are constructed when works and values are perceived as being threatened by oblivion. Without ephemerality and oblivion there is no need for canon lists. Canon and oblivion are linked.Memorials mean canonization of certain individuals, collectives, events and places, while others are allowed to be forgotten. Consequently, archaeological memorials constitute part of the canonization of a few finds and find sites. According to Pierre Nora’s thesis, memorials are established when the places are in danger of being forgotten.Whether one likes canon lists or not, they are a fact. There has always been a process of prioritisation, leading to some finds being preserved and others discarded, some being exhibited and others ending up in the stores.Canonization is expressed in the classical “Seven Wonders of the World”, the “Seven New Wonders of the World” and the World Heritage list. A find may be declared as treasure trove, as being of “unique national significance” or be honoured by the publication of a monograph or by being given its own museum.In practice, the same few finds occur in different contexts. There seems to be a consensus within the subject of canonization of valuing what is well preserved, unique, made of precious metals, bears images and is monumental. A top-ten canon list of prehistoric finds from Denmark according to this consensus would probably include the following finds: The sun chariot from Trundholm, the girl from Egtved, the Dejbjerg carts, the Gundestrup cauldron, Tollund man, the golden horns from Gallehus, the Mammen or Bjerringhøj grave, the Ladby ship and the Skuldelev ships.Just as the past may be used in many different ways, there are many forms of memorial related to monuments from the past or to archaeological excavations. Memorials were constructed in the 18th and 19th centuries at locations where members of the royal family had conducted archaeology. As with most other memorials from that time, the prince is at the centre, while antiquity and archaeology create a brilliant background, for example at Jægerpris (fig. 2). Memorials celebrating King Frederik VII were created at the Dæmpegård dolmen and at the ruin of Asserbo castle. A memorial celebrating Count Frederik Sehested was erected at Møllegårdsmarken (fig. 3). Later there were also memorials celebrating the architect C.M. Smith at the ruin of Kalø Castle and Svend Dyhre Rasmussen and Axel Steensberg, respectively the finder and the excavator of the medieval village at Borup Ris.Several memorials were erected in the decades around 1900 to commemorate important events or persons in Danish history, for example by Thor Lange. The memorials were often located at sites and monuments that had recently been excavated, for example at Fjenneslev (fig. 4).A large number of memorials commemorate abandoned churches, monasteries, castles or barrows that have now disappeared, for example at the monument (fig. 5) near Bjerringhøj.Memorials were erected in the first half of the 20th century near large prehistoric monuments which also functioned as public meeting places, for example at Glavendrup, Gudbjerglund and Hohøj. Prehistoric monuments, especially dolmens, were also used as models when new memorials were created during the 19th and 20th centuries.Finally, sculptures were produced at the end of the 19th century sculptures where the motif was a famous archaeological find – the golden horns, the girl from Egtved, the sun chariot and the woman from Skrydstrup.In the following, this article will focus on a category of memorials raised to commemorate an archaeological find. In Denmark, 24 archaeological find sites have been marked by a total of 26 monuments (fig. 6). This survey is based on excursions, scanning the literature, googling on the web and contact with colleagues. The monuments are presented chronological, i.e. by date of erection. 1-2) The golden horns from Gallehus: Found in 1639 and 1734; two monu­ments in 1907. 3) The Snoldelev runic stone: Found in c. 1780; monument in 1915. 4) The sun chariot from Trundholm bog: Found in 1902; monument in 1925; renewed in 1962 and moved in 2002. 5) The grave mound from Egtved: Found in 1921; monument in 1930. 6) The Dejbjerg carts. Found in 1881-83; monument in 1933. 7) The Gundestrup cauldron: Found in 1891; wooden stake in 1934; replaced with a monument in 1935. 8) The Bregnebjerg burial ground: Found in 1932; miniature dolmen in 1934. 9) The Brangstrup gold hoard. Found in 1865; monument in 1935.10-11) Maglemose settlements in Mulle­rup bog: Found in 1900-02; two monuments in 1935 and 1936. 12) The Skarpsalling vessel from Oudrup Heath: Found in 1891; monument in 1936. 13) The Juellinge burial ground: Found in 1909; monument in 1937. 14) The Ladby ship: Found in 1935; monument probably in 1937. 15) The Hoby grave: Found in 1920; monument in 1939. 16) The Maltbæk lurs: Found in 1861 and 1863; monument in 1942. 17) Ginnerup settlement: First excavation in 1922; monument in 1945. 18) The golden boats from Nors: Found in 1885; monument in 1945. 19) The Sædinge runic stone: Found in 1854; monument in 1945. 20) The Nydam boat: Found in 1863; monument in 1947. 21) The aurochs from Vig: Found in 1904; monument in 1957. 22) Tollund Man: Found in 1950; wooden stake in 1968; renewed inscription in 2000. 23) The Veksø helmets: Found in 1942; monument in 1992. 24) The Bjæverskov coin hoard. Found in 1999; monument in 1999. 25) The Frydenhøj sword from Hvidovre: Found in 1929; monument in 2001; renewed in 2005. 26) The Bellinge key: Found in 1880; monument in 2003.Two monuments (fig. 7) raised in 1997 at Gallehus, where the golden horns were found, marked a new trend. From then onwards the find itself and its popular finders came into focus. At the same time the classical or old Norse style of the memorials was replaced by simple menhirs or boulders with an inscription and sometimes also an image of the find. One memorial was constructed as a miniature dolmen and a few took the form of a wooden stake.The finds marked by memorials represent a broader spectrum than the top-ten list. They represent all periods from the Stone Age to the Middle Ages over most of Denmark. Memorials were created throughout the 20th century; in greatest numbers in the 1930s and 1940s, but with none between 1968 and 1992.The inscriptions mention what was found and, in most cases, also when it happened. Sometimes the finder is named and, in a few instances, also the person on whose initiative the memorial was erected. The latter was usually a representative part of the political agency of the time. In the 18th and 19th centuries it was the royal family and the aristocracy. In the 20th century it was workers, teachers, doctors, priests, farmers and, in many cases, local historical societies who were responsible, as seen on the islands of Lolland and Falster, where ten memorials were erected between 1936 and 1951 to commemorate historical events, individuals, monuments or finds.The memorial from 2001 at the find site of the Frydenhøj sword in Hvidovre represents an innovation in the tradition of marking history in the landscape. The memorial is a monumental hybrid between signposting and public art (fig. 8). It formed part of a communication project called “History in the Street”, which involved telling the history of a Copenhagen suburb right there where it actually happened.The memorials marking archaeological finds relate to the nation and to nationalism in several ways. The monuments at Gallehus should, therefore, be seen in the context of a struggle concerning both the historical allegiance and future destiny of Schleswig or Southern Jutland. More generally, the national perspective occurs in inscriptions using concepts such as “the people”, “Denmark” and “the Danes”, even if these were irrelevant in prehistory, e.g. when the monument from 1930 at Egtved mentions “A young Danish girl” (fig. 9). This use of the past to legitimise the nation, belongs to the epoch of World War I, World War II and the 1930s. The influence of nationalism was often reflected in the ceremonies when the memorials were unveiled, with speeches, flags and songs.According to Marie Louise Stig Sørensen and Inge Adriansen, prehistoric objects that are applicable as national symbols, should satisfy three criteria. The should: 1) be unusual and remarkable by their technical and artistic quality; 2) have been produced locally, i.e. be Danish; 3) have been used in religious ceremonies or processions. The 26 archaeological finds marked with memorials only partly fit these criteria. The finds also include more ordinary finds: a burial ground, settlements, runic stones, a coin hoard, a sword and a key. Several of the finds were produced abroad: the Gundestrup cauldron, the Brangstrup jewellery and coins and the Hoby silver cups.It is tempting to interpret the Danish cultural canon as a new expression of a national use of the past in the present. Nostalgia, the use of the past and the creation of memorials are often explained as an expression of crisis in society. This seems reasonable for the many memorials from 1915-45 with inscriptions mentioning hope, consolation and darkness. However, why are there no memorials from the economic crisis years of the 1970s and 1980s? It seems as if the past is recalled, when the nation is under threat – in the 1930s and 40s from expansive Germany – and since the 1990s by increased immigration and globalisation.The memorials have in common local loss and local initiative. A treasure was found and a treasure was lost, often to the National Museum in Copenhagen. A treasure was won that contributed to the great narrative of the history of Denmark, but that treasure has also left its original context. The memorials commemorate the finds that have contributed to the narrative of the greatness, age and area of Denmark. The memorials connect the nation and the native place, the capital and the village in a community, where the past is a central concept. The find may also become a symbol of a region or community, for example the sun chariot for Trundholm community and the Gundestrup cauldron for Himmerland.It is almost always people who live near the find site who want to remember what has been found and where. The finds were commemorated by a memorial on average 60 years after their discovery. A longer period elapsed for the golden horns from Gallehus; shortest was at Bjæverskov where the coin hoard was found in March 1999 and a monument was erected in November of the same year.Memorials might seem an old-fashioned way of marking localities in a national topography, but new memorials are created in the same period as many new museums are established.A unique find has no prominent role in archaeological education, research or other work. However, in public opinion treasures and exotic finds are central. Folklore tells of people searching for treasures but always failing. Treasure hunting is restricted by taboos. In the world of archaeological finds there are no taboos. The treasure is found by accident and in spite of various hindrances the find is taken to a museum. The finder is often a worthy person – a child, a labourer or peasant. He or she is an innocent and ordinary person. A national symbol requires a worthy finder. And the find occurs as a miracle. At the find site a romantic relationship is established between the ancestors and their heirs who, by way of a miracle, find fragments of the glorious past of the nation. A paradigmatic example is the finding of the golden horns from Gallehus. Other examples extend from the discovery of the sun chariot in Trundholm bog to the Stone Age settlement at Mullerup bog.The article ends with a catalogue presenting the 24 archaeological find sites that have been marked with monuments in present-day Denmark.Jes WienbergHistorisk arkeologiInstitutionen för Arkeologi och ­Antikens historiaLunds Universitet

Shell Signs Concession for Oman Block 10 Shell, along with its partners OQ and Marsa Liquefied Natural Gas LLC (a joint venture between TotalEnergies and OQ), have signed a concession agreement with the Ministry of Energy and Minerals on behalf of the government of the Sultanate of Oman to develop and produce natural gas from Block 10. The parties also signed a separate gas sales agreement for gas produced from the block. The two agreements follow an interim upstream agreement signed in February 2019. The concession agreement establishes Shell as the operator of Block 10, holding a 53.45% working interest, with OQ and Marsa LNG holding 13.36% and 33.19%, respectively. For the initial phase, Petroleum Development Oman (PDO) is building the infrastructure for the project, including the main pipeline to the Saih Rawl gas processing facility, on behalf of the Block 10 venture partners. The venture will drill and hook up wells to maintain the production beyond the initial phase. The block is expected to reach production of 0.5 Bcf/D. Startup is expected within the next 2 years. In addition, Shell and Energy Development Oman (EDO) signed an agreement to process the natural gas from Block 10 in EDO’s Saih Rawl facility. Shell and the government have agreed that, in parallel to the development of Block 10, Shell will develop options for a separate downstream gas project in which Shell could produce and sell low-carbon products and support the development of hydrogen in Oman. Equinor Encounters Oil at Toppand Equinor has discovered oil in the Troll and Fram area in exploration wells 35/10-7 S and 35/10-7 A in the Toppand prospect. Preliminary calculations indicate between 21 million and 33 million BOE of recoverable reserves. Well 35/10-7 S encountered an oil column of around 75 m in the lower part of the Ness formation and in the Etive formation. There were also traces of hydrocarbons in the shale- and coal-dominated upper part of the Brent Group. A total of around 68 m of effective sandstone reservoir of good to very good reservoir quality was encountered in the Ness and Etive formations combined. Exploration well 35/10-7 A encountered a 60-m oil-filled sandstone-dominated interval in the lower part of the Ness formation and in the Etive formation. A total of around 67 m of effective sandstone reservoir of good to moderate quality were encountered in the Ness and Etive formations combined. Geir Sørtveit, senior vice president for exploration and production west operations for Equinor, said, “We are pleased to see that our success in the Troll- and Fram area continues. We also regard this discovery to be commercially viable and will consider tying it to the Troll B or Troll C platform. Such discoveries close to existing infrastructure are characterized by high profitability, a short payback period, and low CO2 emissions.” These wells are the second and third exploration wells in Production License 630. The license was awarded in the 2011 Award in Predefined Areas. The wells were drilled around 8 km west of the Fram field and 140 km northwest of Bergen. Equinor holds a 50% stake and operates Toppand. Partner Wellesley holds the remaining 50% interest. Petrobras Sells Polo Carmópolis Stake to Carmo Petrobras has signed a deal to sell its stake in the onshore Polo Carmópolis area to Carmo Energy for $1.1 billion. The operator said $275 million would be paid up front, another $550 million when the deal closes, and a further $275 million 1 year after closure of the deal, which still needs regulatory approval. The Polo Carmópolis area comprises 11 onshore concessions in the state of Sergipe. Petrobras said in a statement that it is increasingly concentrating its resources on deep and ultradeepwater assets, where it has shown a competitive edge over the years, producing better-quality oil and with lower greenhouse-gas emissions. The Carmópolis Cluster recorded an average production of 7,600 BOPD and 43,000 m3/D of gas from January to November 2021. Eni, EGPC in $1-Billion Pact To Explore Gulf of Suez, Niger Delta Egyptian General Petroleum Corp. (EGPC) has signed an agreement with Italian energy group Eni for oil exploration in the Gulf of Suez and Nile Delta regions. The deal is valued at no less than $1 billion of investments, the petroleum ministry said in late December. The agreement also included a commitment from Eni to additionally spend “not less than $20 million” to drill four wells, the ministry added in a statement. The deal comes as part of the ministry’s strategy to increase production rates and to attempt to offset the natural decline of wells by using the latest technologies in oil-producing areas. Last October, Eni announced three new discoveries in the Meleiha and South West Meleiha concessions in the Western Desert. Eni has been operating in Egypt since 1954 with a current production of about 360,000 BOED. Chevron Transfers Stake in Suriname Block 5 to Shell Chevron has transferred one-third of its 60% equity interest in an offshore Suriname block for which it has a production-sharing agreement to a unit of Royal Dutch Shell, Suriname’s state oil company confirmed. Paradise Oil Company, a subsidiary of Suriname’s state-run Staatsolie, retains its 40% stake in the Block 5 venture as a nonexecutive partner, according to the farmout contract. Staatsolie and Chevron signed a production-sharing contract last October for Block 5, which covers an area of 2235 km2. The deal marked the first time that Staatsolie will participate as a partner in offshore activities. Equinor Increases Ownership in the Statfjord Field Equinor has entered into an agreement to acquire all of Spirit Energy’s production licenses in the Statfjord area which spreads across the Norwegian and UK continental shelves and are developed by three integrated production platforms (Statfjord A, B, C). All licenses are operated by Equinor. Equinor will pay $50 million, plus a contingent payment linked to commodity prices for the period between October 2021 to December 2022. The transaction has a commercial effective date from 1 January 2021, which is expected to result in a net payment to Equinor at closing. Spirit Energy’s daily production from the Statfjord area in the third quarter of 2021 was around 21,000 BOED. The transaction is part of a larger deal including Spirit Energy’s shareholders, Centrica Plc and Stadtwerke München, who are exiting their portfolio in Norway and selling their assets to Sval Energi. The sale to Sval Energi includes all assets with the exclusion of Statfjord. Statfjord marked its 40th year of production in 2019. One of the earliest oil fields on the Norwegian Continental Shelf, it has produced 5.1 billion BOE. Equinor has recently launched a plan to extend the life of the field toward 2040. The closing of the transaction is subject to certain conditions, including customary government approval, and is expected to be completed by the first half of 2022. Shell Hits Oil at Blacktip North in US GOM Shell has struck oil at the Blacktip North prospect located in the Alaminos Canyon block 336 in the deepwater US Gulf of Mexico. The Blacktip North well encountered about 300 ft net oil pay at multiple levels. The well was drilled to a total depth of 27,770 ft by Transocean drillship Deepwater Poseidon. Blacktip North is about 30 miles northeast of the Whale discovery, 4.5 miles northeast of the 2019 Blacktip discovery, and 42 miles from the Perdido spar hub platform. Shell operates the Blacktip North prospect with an 89.49% interest. Spain’s Repsol holds the remaining 10.51% stake. Petrobras Plans Equatorial Margin Drilling Program Petrobras is preparing to drill the first of 14 planned wells at South America’s new deepwater frontier, the Equatorial Margin at its Northern maritime border, a company executive told the World Petroleum Congress in December. Petrobras plans to invest $2 billion in exploration at the Equatorial Margin through 2026, Reservoir Executive Manager Tiago Homem said. The company estimates an overall investment of $2.5 billion in seismic activities over the same period. CLOV Tieback Goes Onstream Offshore Angola TotalEnergies, operator of Block 17 in Angola, has begun production from the CLOV Phase 2 project, connecting to the existing CLOV FPSO. The tieback project is expected to reach a production of 40,000 BOED in mid-2022. Located about 140 km from the Angolan coast, in water depths from 1100 to 1400 m, the CLOV Phase 2 resources are estimated at around 55 million BOE. Block 17 is operated by TotalEnergies with a 38% stake, Equinor (22.16%), ExxonMobil (19%), BP Exploration Angola Ltd. (15.84%), and Sonangol P&P (5%). The contractor group operates four FPSOs in the main production areas of the block: Girassol, Dalia, Pazflor, and CLOV. Canacol Strikes Gas With Siku-1 in Colombia Canacol Energy’s Siku-1 exploration well encountered 33 ft true vertical depth of net gas pay with an average porosity of 20% within the primary Cienaga de Oro sandstone reservoir target. The company has completed casing the well and will return with a workover rig in early 2022 to complete and tie the well into permanent production. The well was drilled to a total depth of 8,825 ft. The rig was mobilized to drill the Clarinete-6 development well, which reached a total depth of 7,478 ft measured depth and encountered 174 ft true vertical depth of net gas pay. The well was tied into the Clarinete production manifold and has been placed on permanent production. Next up for the rig is the Toronja-2 development well, which is targeting gas-bearing sandstones within the Porquero sandstone reservoir. Following the completion of that well, the rig will be mobilized to spud the Carambolo-1 exploration well, expected in the second half of February. The well is expected to take 5 weeks to drill and complete.

Sonadrill Lands Contract for Drillship Seadrill confirmed a new contract has been secured by Sonadrill Holding, Seadrill’s 50:50 joint venture with an affiliate of Sonangol for the drillship West Gemini. Sonadrill has secured a 10‑well contract with options for up to eight additional wells in Angola for an unknown operator. Total contract value for the firm portion of the deal is expected to be around $161 million, with further revenue potential from a performance bonus. The rig is expected to begin the work in the fourth quarter of this year with a firm term of about 18 months, in direct continuation of the West Gemini’s existing contract. The West Gemini is the third drillship to be bareboat chartered into Sonadrill, along with two Sonangol‑owned units, the Sonangol Quenguela and Sonangol Libongos. Seadrill will manage and operate the units on behalf of Sonadrill. Together, the three units position the Seadrill joint venture as an active rig operator in Angola, furthering the goal of building an ultradeepwater franchise in the Golden Triangle and driving efficiencies from rig clustering in the region. Petrobras Receives TotalEnergies, Shell Payments for Atapu TotalEnergies and Shell have formalized payments to Petrobras for separate, minority stakes in the pre‑salt Atapu field in the Santos Basin. TotalEnergies paid $4.7 billion reais ($940 million) while Shell paid closer to $1.1 billion. The Atapu block was acquired by the consortium comprising Petrobras (52.5%), Shell (25%), and TotalEnergies (22.5%) in the Second Bidding Round for the Transfer of Rights auction held 17 December 2021. The payments are compensation for monies spent thus far by Petrobras, which was granted contractual rights to produce 550 million BOE from Atapu in 2010. The partners will now work together to produce additional volumes from the field. Production at Atapu started in June 2020 via the P-70 FPSO. The unit is in about 2000 m of water and has the capacity to produce 150,000 BOED. CNOOC Brings New Bohai Sea Discoveries On Stream CNOOC Limited has kicked off production from its Luda 5‑2 oil field North Phase I project and Kenli 6‑1 oil field 4‑1 Block development project. Luda 5‑2 is in the Liaodong Bay of Bohai Sea, with average water depth of about 32 m and utilizes a thermal recovery wellhead platform and production platform tied into the Suizhong 36‑1 oil field. A total of 28 development wells are planned, including 26 production wells and two water‑source wells. The project is expected to reach its peak production of 8,200 B/D of oil in 2024. Kenli 6‑1 is in the south of Bohai Sea, with average water depth of about 17 m. The resource is being developed by a wellhead platform in addition to fully utilizing the existing processing facilities of the Bozhong 34‑9 oil field. A total of 12 development wells are planned, including seven production wells and five water‑injection wells. The field is expected to reach its peak production of 4,000 B/D of oil later this year. CNOOC Limited is operator and sole owner of the Luda 5‑2 oil field North and the Kenli 6‑1 oil field 4‑1 Block. Stabroek Block Bounty Off Guyana Gets Bigger The partners in the prolific Stabroek Block have again increased the gross discovered recoverable resource estimate for the area offshore Guyana. The owners now believe they have discovered reserves of at least 11 billion BOE, up from the previous estimate of more than 10 billion BOE. The updated resource estimate includes three new discoveries on the block at Barreleye, Lukanani, and Patwa in addition to the Fangtooth and Lau Lau discoveries announced earlier this year. The Barreleye‑1 well encountered approximately 70 m of hydrocarbon‑bearing sandstone reservoirs of which 16 m is high‑quality oil‑bearing. The well was drilled in 1170 m of water and is located 32 km southeast of the Liza field. The Lukanani‑1 well encountered 35 m of hydrocarbon‑bearing sandstone reservoirs of which approximately 23 m is high‑quality oil‑ bearing. The well was drilled in water depth of 1240 m and is in the southeastern part of the block, approximately 3 km west of the Pluma discovery. The Patwa‑1 well encountered 33 m of hydrocarbon‑bearing sandstone reservoirs. The well was drilled in 1925 m of water and is located approximately 5 km northwest of the Cataback‑1 discovery. “These new discoveries further demonstrate the extraordinary resource density of the Stabroek Block and will underpin our queue of future development opportunities,” said John Hess, chief executive of Hess and a partner in Stabroek. The co‑venturers have sanctioned four developments to date on Stabroek with both Liza and Liza Phase 2 on stream. The third planned development at Payara is ahead of schedule and is now expected to come on line in late 2023; it will utilize the Prosperity FPSO with a production capacity of 220,000 BOPD. The fourth development, Yellowtail, is expected to come on line in 2025, utilizing the ONE GUYANA FPSO with a production capacity of 250,000 BOPD of oil. At least six FPSOs with a production capacity of more than 1 million gross BOPD are expected to be on line on the Stabroek Block in 2027, with the potential for up to ten FPSOs to develop gross discovered recoverable resources. The Stabroek Block is 6.6 million acres. ExxonMobil affiliate Esso Exploration and Production Guyana Limited is operator and holds 45% interest; Hess Guyana Exploration holds 30% interest; and CNOOC Petroleum Guyana Limited holds 25%. ConocoPhillips Gets Ekofisk License Extension Norway’s Ministry of Petroleum and Energy (MPE) has extended production licenses in the Greater Ekofisk Area from 2028 to 2048 with ConocoPhillips as operator. The company said the license extension provides long‑term operations and resource management aligned with the company’s long‑term perspective on the Norwegian continental shelf. Fields on the shelf are required to operate with a valid production license where the operator and licensees enter into an agreement with the authorities, including relevant field activities. The authorities may require commitments, leading to increased oil recovery. The existing production licenses 018, 018 B, and 275 in the Greater Ekofisk Area were set to expire on 31 December 2028; however, the MPE approved an extension through 2048. The new terms provide a potential for extending Ekofisk’s lifetime to nearly 80 years. The license partners are ConocoPhillips (operator, 35.11%), TotalEnergies EP Norge (39.896%), Vår Energi (12.388%), Equinor (7.604%), and Petoro (5%). BHP’s Wasabi Disappoints in US GOM Australian operator BHP encountered noncommercial hydrocarbons with its Wasabi‑2 well in the US Gulf of Mexico. BHP said the well in Green Canyon Block 124 was plugged and abandoned following the disappointing results. “This completes the Wasabi exploration program, with results under evaluation to determine next steps,” the company said. The well was targeting oil in an early Miocene reservoir. Transocean drillship Deepwater Invictus spudded the well in 764 m of water in November 2021. The previous Wasabi‑1 well had a mechanical problem and was plugged and abandoned 4 days earlier, prior to reaching its prospective targets. BHP operates Wasabi with a 75% interest. Lukoil Says Titonskaya Holds 150 Million BOE Russia’s Lukoil believes it has discovered around 150 million BOE following analysis of the two wells it drilled at the Titonskaya structure on the Caspian Sea shelf. Work is now underway to refine the seismic models of productive deposits and study deep samples of formation fluids. The results of the assessment will be submitted to the State Reserves Commission of the Russian Federation. The structure is in the central part of the Caspian Sea, not far from the Khazri field. Lukoil drilled the first well at the Titonskaya structure in 2020 and announced the new discovery in April 2021. According to that assessment, the probable geological resources of the Titonskaya are 130.4 million tons. In 2021, drilling of the second prospecting and appraisal well began to identify oil and gas deposits in the terrigenous‑carbonate deposits of the Jurassic‑ Cretaceous age. The well was drilled using the Neptune jackup drilling rig. The new find at Titonskaya will likely be tied into Khazri infrastructure. Petrobras’ Roncador IOR Project Comes On Line Petrobras has successfully started production from the first two wells of the improved oil recovery (IOR) project at the Roncador field in the Campos Basin offshore Brazil. The two wells are the first of a series of IOR wells to reach production. Startup is almost 5 months ahead of schedule and at half of the planned cost, according to partner Equinor. The wells will add a combined 20,000 BOED to Roncador, bringing daily production to around 150,000 bbl and reducing the carbon intensity (emissions per barrel produced) of the field. Through this first IOR project, the partnership will drill 18 wells that are expected to provide additional recoverable resources of 160 million bbl. Improvements in well design and the partners’ combined technological experience are the main drivers behind the 50% cost reduction across the first six wells, including the two in production. Roncador is Brazil’s fifth‑largest producing asset and has been in production since 1999. Petrobras operates the field and holds a 75% stake. In 2018, Equinor entered the project as a strategic partner with the remaining 25% interest. In addition to the planned 18 IOR wells, the partnership believes it can further improve recovery and aims to increase recoverable resources by a total of 1 billion BOE. The field has more than 10 billion BOE in place under a license lasting until 2052. The strategic alliance agreement also includes an energy‑efficiency and CO2‑emissions‑reduction program for Roncador. Gazania-1 To Spud Off South Africa Africa Energy will move ahead with its planned Gazania‑1 wildcat well offshore South Africa after securing partner Eco Atlantic’s $20 million in capital requirements for its portion of the probe. The well will be drilled in Block 2B. Island Drilling semisubmersible Island Innovator has been contracted for the work and is expected to mobilize from its current location in the North Sea for the 45‑day trip to South Africa. The Block 2B joint venture plans to spud the well by October with drilling expected to last 30 days, including a full set of logs if the well is successful. The block has significant contingent and prospective resources in relatively shallow water and contains the A‑J1 discovery that flowed light sweet crude oil to surface. Gazania‑1 will target two large prospects 7 km updip from A‑J1 in the same region as the recent Venus and Graff discoveries. Block 2B is located offshore South Africa in the Orange Basin where both TotalEnergies and Shell recently announced significant oil and gas discoveries offshore Namibia. The block covers 3062 km2 approximately 25 km off the west coast of South Africa near the border with Namibia in water depths ranging from 50 m to 200 m. The Southern Oil Exploration Corp. (Soekor) discovered and tested oil on Block 2B in 1988 with the A‑J1 borehole, which intersected thick reservoir sandstones between 2985 m and 3350 m. The well flowed 191 B/D of 36 °API oil from a 10‑m sandstone interval at around 3250 m. Africa Energy has a 27.5% interest in Block 2B offshore South Africa. The block is operated by a subsidiary of Eco Atlantic which holds a 50% interest. A subsidiary of Panoro Energy holds a 12.5% stake, and Crown Energy AB indirectly holds the remaining 10%. Brazil Grants New Exploration Blocks Brazil’s National Agency of Petroleum, Natural Gas, and Biofuels (ANP) has granted 59 exploratory blocks of oil and natural gas to 13 companies, including Shell, TotalEnergies, and 3R Petroleum. The awards were part of a permanent bid offer round held in Rio de Janiero in April. The auction totaled 422.4 million reais in signature bonuses with leases granted in six Brazilian states: Rio Grande do Norte, Alagoas, Bahia, Espírito Santo, Santa Catarina, and Paraná. The awards will result in investments of 406.3 million reais in the exploratory phase of the contracts. Shell Brazil (70%) was granted six blocks in the Santos Basin in a consortium with the Colombian Ecopetrol (30%). The blocks leases were SM‑1599, SM‑1601, SM‑1713, SM‑1817, SM‑1908, and SM‑1910. TotalEnergies won two areas in the same basin while Brazilian company 3R Petroleum received six areas in the Potiguar Basin. Petro‑Victory was also awarded 19 new blocks in Potiguar, increasing its holdings in Brazil to 38 blocks (37 in Potiguar). The new blocks are nearby Petro‑Victory infrastructure at the Andorinha, Alto Alegre, and Trapia oil fields. Eni Finds More Oil in Egypt’s Western Desert Eni struck new oil and gas reserves with a trio of discoveries in the Meleiha concessions of Egypt’s Western Desert. The finds have already been tied into existing infrastructure in the region and have added around 8,500 BOED to overall production from the area. The operator drilled the Nada E Deep 1X well, which encountered 60 m of net hydrocarbon pay in the Cretaceous‑Jurassic Alam El Bueib and Khatatba formations Meleiha SE Deep 1X well, which found 30 m of net hydrocarbon pay in the Cretaceous‑Jurassic sands of the Matruh Khatatba formations, and the Emry Deep 21 well, which encountered 35 m of net hydrocarbon pay in the massive cretaceous sandstones of Alam El Bueib. The results, added to the discoveries of 2021 for a total of eight exploration wells, give Eni a 75% success rate in the region. The company added that additional exploration activities in the concession are ongoing with “promising indications.” With these discoveries, Eni, through AGIBA, a joint venture between Eni and EGPC, continues to pursue its near‑field strategy in the mature basin of the Western Desert, aimed at maximizing production by containing development costs and minimizing time to market. Eni is planning a new high‑resolution 3D seismic survey in the Meleiha concession this year to investigate the gas potential of the area. Eni is currently the leading producer in Egypt with an equity production of around 360,000 BOED.

The objective of this study was to analyze the eco-epidemiological aspects of Leptospira seroprevalence and seroincidence and its associated factors in two municipalities of northwest Colombia. A prospective study was performed in rural areas of Urabá, Antioquia, Colombia. The study enrolled 597 people between November 2015 and January 2016, of which 274 were followed up 1 year later. Serologic testing was performed by a microscopic agglutination. The outcomes were seroprevalent and seroincident cases, and the primary exposure was an outdoor occupation. A binary and mixed-effect multinomial logistic regression model was used to estimate factors associated with seroprevalent or seroincident cases of Leptospira infection. The overall Leptospira seroprevalence was 27.81% (95% confidence interval: 23.62–32.49), and the overall cumulative seroincidence for Leptospira was 14.60% (95% confidence interval: 10.33–20.23). Multivariable analysis showed that factors associated with L. interrogans serogroups seropositivity were outdoor occupation, male gender, older age, the presence of dirt floor in the household, and the presence of piglets and opossums. It also showed that factors associated with other Leptospira species serogroups were the presence of pit latrines and of turkeys. In addition, the multivariable model of seroincident cases of L. interrogans serogroups evidenced outdoor occupations, the presence of rats, and corn cultivation as risk factors. Likewise, the multivariable model for seroincident cases of other Leptospira species showed that the presence of hunting canines and cassava cultivation were risk factors. We found specific factors associated with the transmission of Leptospira serogroups contribute to the understanding of the epidemiology of Leptospira infection in rural areas of Urabá, Colombia.

Photo ID 131102170 © Geckophotos | Dreamstime.com INTRODUCTION Medical tourism should contribute to developing a more robust healthcare system that acts in the best interests of patients and ensures equal access to healthcare. This paper examines medical tourism in Colombia and argues that developing a system that aligns with bioethical principles is necessary. People traveling for care should have access to the Ministry of Health rather than only the Ministry of Industry and Tourism, emphasizing their purpose as patients seeking medical procedures or treatments rather than tourists engaging in leisure activities. Additionally, in the interest of justice, Colombian patients should benefit from the revenue derived from medical tourism. It is crucial to recognize that both patients traveling for care and people in the destination country can derive benefits from medical tourism. The Colombian government can protect the rights and well-being of patients seeking care and ensure that any benefits are distributed fairly among Colombian citizens. I. Background Medical tourism refers to people traveling to foreign countries to obtain health care.[1] Many individuals from high-income countries seek health care in less developed countries to take advantage of the lower costs. Destination countries are increasingly showing interest in becoming medical tourism hubs due to the significant financial potential of this multi-billion dollar industry. The global medical tourism market is projected to reach $207.9 billion by 2027.[2] This growth not only generates income but also creates employment opportunities and business prospects for local residents in sectors such as tourism, pharmaceuticals, and infrastructure. By establishing themselves as medical tourism destinations, countries can stimulate economic development and enhance their healthcare structure. Colombia is among the fastest-growing medical tourism destinations in the world. It has become a popular destination for medical tourists due to its advanced healthcare infrastructure, biotechnology, and highly skilled physicians who cater to international patients at affordable prices.[3] The healthcare entities in Colombia offer a wide range of medical procedures, including cardiovascular, bariatric, orthopedics, cosmetic surgery, dental care, and fertility treatments. [4] The Colombian government has actively promoted medical tourism to position the country as a destination for world-class medical services.[5] Through strategic economic policies, effective regulation, and digital marketing, medical tourism has emerged as a significant contributor to Colombia’s income. The Colombian Ministry of Industry and Tourism, which regulates medical tourism in Colombia, forecasts at least 2.8 million health tourists and a revenue of at least $6.3 billion by 2032.[6] Colombia intends to have medical tourism play a significant role in its economy. However, ethical issues exist. The Colombia Ministry of Industry and Tourism is more involved in medical tourism than the Ministry of Health is. Additionally, the government has not been held accountable for the shortcomings in the medical tourism industry. There should be an organization advocating for the rights and well-being of medical tourists. Furthermore, using public funds to attract international patients may divert funds from local communities. Last, the negative impacts of medical tourism on Colombian patients deserve attention. This paper aims to explore these ethical issues from two perspectives: that of medical tourists and that of Colombian citizens. I argue that the benefits of medical tourism outweigh the harms but that those traveling for health care deserve protection. II. Patients: Are They International Patients or Tourists? When medical tourists seek hospitals and physicians in a destination country, facilitators may direct them to non-licensed practitioners and questionable facilities. These facilitators, who receive commissions, may not act in the patient’s best interest. Rather, like travel agents, they base their referrals on the referral fees that hospitals or physicians pay.[7] International patients risk getting lower-quality health care from unregulated hospitals or providers. This can interfere with informed consent and increase the risk of infections. There may be an absence of medical malpractice coverage from physicians. Unregulated or unlicensed medical care may even lead to patient fatalities. Therefore, it is crucial for international patients to carefully evaluate the risks associated with “booking” their healthcare options. To mitigate these risks, it is important for international patients to thoroughly assess the accreditation status of the hospital or clinic they plan to visit. The Joint Commission International (JCI) accreditation can provide patients with an external quality assessment and assist them in making an informed decision.[8] International patients should proactively seek out certified and reputable healthcare providers and institutions to ensure both their safety and a high quality of care. Colombia has five hospitals and clinics with JCI accreditation.[9] Colombia is the third most-used destination for plastic surgery in the world; the first is Brazil, and the second is Turkey. In Colombia, one out of every three plastic surgery patients is an international patient.[10] The Colombian Association for Plastic Surgery advises all patients to check the hospital's accreditation. Patients should check the website of the local Secretary of Health in each city and see if the physician conducting the plastic surgery is listed.[11] Institutions and doctors must fully comply with requirements, including describing the procedure and obtaining informed consent from patients. It is very common to read in the media plastic surgeries conducted in what is known in Latin America as “clinicas de garage” (garage clinics) with negative results and deaths.[12] Official data covers plastic surgeries conducted at accredited institutions with registered doctors. There is a lack of data on garage clinics. There are a few things the government can do to make medical tourism safer. First, the Ministry of Health’s website should maintain a list of healthcare providers with JCI accreditation. In each city, the local Secretary of Health is responsible for providing patients with information about the quality of care of the hospitals in its region. Second, the government should take responsibility for providing accurate and comprehensive information to international patients, enabling them to make fully informed decisions regarding their medical procedures. In the context of informed consent, patients may have trouble understanding due to language barriers, terminology, and the complexity of the risks involved in medical procedures. Lastly, Congress should enact a legal framework that determines the responsibility of all parties involved in medical tourism.[13] In the unfortunate event that a medical tourist requires intensive care, it becomes imperative to determine who will bear the responsibility for their well-being and any potential financial implications. Medical tourists are not protected from errors and failures of medical procedures because the Colombia Constitution specifies that the healthcare system exclusively caters to its citizens, while coverage for foreigners is limited to emergencies only. The US State Department recommends that those traveling to Colombia have international health insurance.[14] International patients can sue doctors in Colombia for medical malpractice, referred to as medical liability.[15] The government should take responsibility for certifying medical institutions and issuing medical visas with specific requirements and regulations specific to medical tourism.[16] A new medical visa system is in place. Changing the terminology may help the government see those traveling for care as medical patients rather than medical tourists. That may lead to a different mindset and spur the government to protect them and ensure high-quality care. It may also help those traveling avoid tourism industry facilitators and find reputable surgeons and hospitals. III. Are Colombian Patients and the Local Healthcare System Benefiting from Medical Tourism? The main reason for the growth of medical tourism from developed countries to developing countries like Colombia is the excessive cost of treatment in wealthier nations.[17] Other reasons include the long queues for certain types of medical services in the home country, the availability of better technologies abroad, inadequate (or absence of) health insurance, and the unavailability[18] (or prohibition) of certain medical services in the home country.[19] The Colombian Constitution recognizes health as a fundamental right for all citizens.[20] Pursuant to the Constitution’s health mandate, Colombia designed a mandatory universal social health insurance system in 1993. It aims to achieve a fair distribution of resources, opportunities, and services while holding the government accountable.[21] Before 1993, less than 25 percent of the population had coverage; now, between 94 and 99 percent have it, regardless of income level or employment.[22] However, universal care does not entitle Colombian citizens to many of the modern surgical centers, technology, and doctors that tourists access. Local wealthy Colombian citizens tend to purchase private insurance that allows them many more healthcare options.[23] The OECD reports that only 41 percent of Colombian citizens were satisfied with the availability of the quality of care, while the OECD average is 67 percent. According to the OECD, the out-of-pocket health expenditure in Colombia is 14 percent, which is lower than the OECD average of 18 percent. Despite its recognized right to health care, the current system is not providing the quality of care that the people would prefer. Those traveling to Colombia for care are not covered by universal social health insurance and must pay for their health care[24] out of pocket or through their private insurers using international coverage.[25] Like local supplemental private insurance, medical tourists and their insurance plans tend to pay more for their care than the rate that the universal system would pay the providers for care provided to the general Colombian population. This situation often leads to higher revenue from medical tourists than local patients unless the local patients have supplemental private insurance. The mismatched payment schemes leave the local population with unequal access to healthcare resources[26] since healthcare providers prefer to cater to patients paying more than the government-subsidized insurance pays. Medical tourism “threatens to result in a dual market structure”[27] characterized by a higher-quality, expensive segment that serves wealthy nationals and foreigners alongside a lower-quality segment that caters to the poor, most of whom are covered by universal healthcare coverage.[28] Medical tourists should pay taxes or a special premium to improve the local healthcare system. While the medical tourism industry arguably generates tax revenue,[29] some additional money should flow from the medical tourists to the healthcare outlets that the local people use. Then, the country can benefit even more from promoting medical tourism while ensuring that the government and the healthcare system follow the principles of justice, beneficence, and public welfare.[30] In Colombia, Fundación Cardioinfantil, a private non-profit hospital known as “La Cardio,” is a good example of a regional leader committed to providing clinical excellence to both national and international patients.[31] About 20 years ago, La Cardio, well known for its cardiovascular health care, aimed to become the top hospital in the region (Latin America and the Caribbean) to obtain financial resources for improving its facilities. It became the first hospital in Colombia to achieve the JCI accreditation, attracting patients from countries with inadequate cardiovascular healthcare systems.[32] Foreign governments covered their citizens’ medical expenses, allowing La Cardio to fund system improvement. Currently ranked as the fifth-best clinic in Latin America and having won the Gold Award for Corporate Social Responsibility, La Cardio has received recognition for its dedication to serving economically disadvantaged Colombian patients.[33] This example demonstrates how introducing a high-paying market has not led to neglecting local patients, as resources from medical tourists are used to enhance the healthcare system for the local population. CONCLUSION The Colombian government needs to recognize that international patients are seeking medical services, not tourism or vacation experiences. Therefore, a new policy should categorize international patients separately from the tourism sector and treat them purely as patients. The introduction of medical visas may help this. Once establishing international patients are patients and not tourists, the Colombian government could impose taxes on them and allocate the funds generated to reinvest in the healthcare needs of its citizens, ensuring justice and promoting awareness of the ethical rights of international patients. At the same time, home country governments directing patients to a destination country should conduct thorough due diligence of the ethical principles applied to international patients as well as the accreditation of the destination country’s hospitals. Colombia may be aware of the implications of the difference in terms but unwilling to modify the language due to the associated costs, liabilities, and risks involved. - [1] Gaines, J., Lee, C. V. (2019). Medical tourism. Travel Medicine, 371–375. https://doi.org/10.1016/b978-0-323-54696-6.00039-2 https://www.sciencedirect.com/science/article/pii/B9780323546966000392 [2] Forecasted Evolution of Medical Travels, 2023-2027: A Segmental View. ReportLinker. (2023, December). https://www.reportlinker.com/p06473784/Medical-Tourism-Market-Size-Share-Trends-and-Analysis-by-Region-Service-Provider-and-Segment-Forecast.html [3] Forecasted Evolution of Medical Travels, 2023-2027: A Segmental View. ReportLinker. (2023, December). [4] Arias-Aragonés, F.J.A., Payares, A.M.C., & Jiménez, O.J. (2020). Characterization of the healthcare tourism in the city of Bogotá and the District of Cartagena. Clío América, 14 (28), 486-492. https://doi.org/10.21676/23897848.3941 [5] Arias-Aragonés, et al. (2020). [6] Arias- Aragones, et al. (2020). https://www.colombiaproductiva.com/ptp-sectores/historico/turismo-salud (citing the Colombian Production Transformation Program (PTP)) [7] Glenn Cohen, Patients with Passports Medical Tourism, Law, and Ethics. New York Oxford University Press, 2015, p. 25 [8] Glenn, Cohen. (2015), p. 23-24. [9] A Global Leader for Health Care Quality and Patient Safety. Joint Commission International. https://www.jointcommissioninternational.org/ (The five Colombian hospitals and clinics with JCI accreditation are two hospitals in the capital city Bogota (la Cardio and Fundación Hospital Universitario Santa Fé de Bogotá), one hospital in Cali (Clinica Inbanaco), one hospital in Medellín (Hospital Pablo Tobón), and one clinic in Florida Blanca (Fundación Cardiovascular de Colombia). Nearby countries such as Venezuela and Trinidad Tobago do not have any accredited hospitals or clinics. Ecuador and Panamá have one each, Perú has eleven, and Brazil has seventy-one.) [10] International Society of Aesthetic Plastic Surgery ISAPS (2023), ISAPS International Survey on Aesthetic/Cosmetic Procedures performed in 2022, p. 52. https://www.isaps.org/discover/about-isaps/global-statistics/reports-and-press-releases/global-survey-2022-full-report-and-press-releases/ (most frequently cited countries of foreign patients in Colombia are the US, Spain, and Panama.) [11] Why choose a member of the SCCP. (2023). Colombia Plastic Surgery Association (SCCP). https://cirugiaplastica.org.co/porque-elegir-un-miembro-de-la-sccp/ See also: To Find a Surgeon. (2023). Colombia Plastic Surgery Association (SCCP). https://cirugiaplastica.org.co (This website is helpful for checking the list of members of the SCCP.) [12] Cosmetic Surgeries Performed in Garage Offices can Become a Public Health Problem. Concejo de Bogotá D.C. (2022). https://concejodebogota.gov.co/cirugias-esteticas-practicadas-en-consultorios-de-garaje-se-pueden/cbogota/2015-07-17/100100.php (There are many cases of deaths resulting from illegal plastic surgeries. The local government in Bogota is aware of the deaths, as reported in the Bogota Counsel (2015)). See also Travel.State.Gov, US Department of State, Bureau of Consular Affairs. (August 17, 2023). https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Colombia.html (There is a warning that says: “Although Colombia has many elective/cosmetic surgery facilities that are on par with those found in the United States, the quality of care varies widely. If you plan to undergo surgery in Colombia, carefully research the doctor and recovery facility you plan to use. Make sure that emergency medical facilities are available, and that professionals are accredited and qualified. Share all health information (e.g., medical conditions, medications, allergies) with your doctor before surgery.") [13] Arias-Aragonés, F.J.A., Payares, A.M.C., & Jiménez, O.J. (2020), p. 490. (report “the absence of regulation and a legal framework that determines the responsibilities of each link in the production chain” as a difficulty that affects competitivity to become a leader in medical tourism in the Latin American region.) See also: Trujillo, M. A. (2023, November 24). Colombia’s New Bill on Regulating Cosmetic Surgeries. BNN Breaking. https://bnn.network/breaking-news/health/colombia-to-regulate-cosmetic-surgeries-a-step-towards-patient-safety/ (On November 22, 2023, as a response to rising cases of death and injuries associated with plastic surgeries, a bill was introduced in the Colombian House of Representatives to regulate the practice of cosmetic surgeries and protect the integrity of patients) [14] U.S. Department of State, Travel.State.Gov, Colombia. (August 17, 2023). Traveler’s Checklist, https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Colombia.html [15] U.S. Department of State, Travel.State.Gov, Colombia. (August 17, 2023). Traveler’s Checklist. See also: Medical Tourism and Elective Surgery. The Department of State informs that “U.S. citizens have suffered serious complications or died during or after having cosmetic surgery or other elective surgery“ and “the legal options in cases of malpractice are very limited in Colombia,” https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Colombia.html See also: The law firm Alvarez Gonzalez Tolosa Attorneys. (August 8, 2023). Medical Malpractice in Colombia, includes medical malpractice as one of the areas of expertise of the firm. https://www.agtattorneys.com/blog/medical-malpractice-in-colombia/ [16] Colombia recently enacted a new visa regulation (Resolution 5477 from July 22, 2022, issued by the Ministry of Foreign Affairs) effective as of October 22, 2022. No data currently exists about a "medical treatment" visa because it is a new legislation. Even though the regulation refers to the visitor as a patient and includes requirements such as (1) a letter from the medical institution explaining the treatment and approximate duration, (2) a letter explaining costs and who will pay for the treatment, (3) insurance policy, and (4) the general requirements for tourists, the regulation specifically explains that this kind of visa is considered as a TOURISM visa (art 37). [17] Glenn, Cohen. 2015 [18] Frequently Asked Questions. Bioxcellerator. https://www.bioxcellerator.com/faqs (For example, Bioxellerator stem cell therapies conducted in Medellin, Colombia, are not FDA-approved.) [19] Vovk, Viktoriia, Lyudmila Beztelesna, and Olha Pliashko. (2021). "Identification of Factors for the Development of Medical Tourism in the World" International Journal of Environmental Research and Public Health 18, no. 21: 11205. https://doi.org/10.3390/ijerph182111205 [20] Colombian Constitution. (1991). art. 49 [21] Ministry of Health and Protection. Columbia Ministry of Health. (2023). https://www.minsalud.gov.co/English/Paginas/Ministry.aspx [22] “Does Colombia’s Health System Need an Overhaul?” (March 2, 2023). The Dialogue, Latin America Advisor. https://www.thedialogue.org/analysis/does-colombias-health-system-need-an-overhaul/ [23] Health at a Glance 2021 Colombia Country Note. OECD. (2023). https://search.oecd.org/colombia/health-at-a-glance-Colombia-EN.pdf [24] Travel.State.Gov, US Department of State, Bureau of Consular Affairs. https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Colombia.html [25] Glenn, Cohen. (2015). p. 2-9. [26] Banco de la República. (2023). Regional Health Inequalities in Colombia. https://www.banrep.gov.co/en/regional-health-inequalities-colombia (The Central Bank of Colombia (“Banco de la República”) in reports that despite having relatively high health coverage compared with other countries, empirical results show persistent inequalities in the healthcare system. The aim is to reduce and eventually eliminate such inequalities.) [27] Glenn, Cohen (2015), p. 158-160, citing Rupa Chanda, an Indian business professor, Trade in Health Services, 80 Bull. World Health Org. 158, 160 (2002). [28] Banco de la República. (2023). Regional Health Inequalities in Columbia. https://investiga.banrep.gov.co/es/be-1233. (Under Colombian law, it is mandatory for all employees and employers to pay 4 percent and 8 percent of the applicable salary, respectively, to the universal healthcare system (EPS) to obtain coverage for the employee and family members. This is known as the contributive system, and the funding is known as parafiscal. The unemployed obtain coverage through the government-subsidized system known as SISBEN (System of Identification of Beneficiaries of Social programs), funded with taxpayers’ money, known as fiscal funding. According to the Central Bank of Colombia (Banco de la República), “in recent years, the healthcare sector has faced financial and administrative problems that have increased the need for fiscal resources for its financing and that could affect its sustainability. Regarding the composition of the outflow, it is worth noting the cost of ensuring the contributory and subsidized regime, which on average explains 80 percent of the total system expenses during the period 2011-2022.” “Additionally, pressures derived from the Covid-19 pandemic, Venezuelan migration” and expenses derived from the increase in the subsidized system due to the high rate of unemployment and informal employment are negatively impacting financing of the healthcare system in Colombia. Additional fiscal resources are needed because the health care Colombians receive costs more than what beneficiaries pay.) [29] Statista. (2023). Revenue of the medical tourism sector in Colombia from 2019 to 2024 https://www.statista.com/statistics/1156551/colombia-revenue-medical-tourism/ [30] Glenn, Cohen. (2015), p.218 (The beneficence principle is the general moral obligation to act for the benefit of others, and some of those acts are obligatory, as is the government’s obligation concerning healthcare.) [31] Hospital Cardioinfantil Bogotá, Colombia. https://cardioinfantil.org [32] Hospital Cardioinfantil https://cardioinfantil.org (Trinidad and Tobago, Aruba, Curacao, and Panamá were the first countries with international agreements with La Cardio.) [33] Hospital Cardioinfantil Bogotá, Colombia. https://www.lacardio.org/historia/

Abstract Background and Aims Mineral bone disease in dialysis patients is an important predictor of morbimortality.iPTH levels had been previously associated with different parameters, but not clearly to diabetic disease (DBT). We aim to analyze relationship between DBT and iPTH levels in a large cohort of dialysis patients from Fresenius Medical Care LatinAmerica (FMC LA). Method Prevalent dialysis patients (more than 90 days on renal replacement therapy) by November 2019 in FMC LA dialysis units (Argentina, Brasil, Chile, Colombia, Ecuador, Perú) were included into the dataset. We obtained demographic, treatment and laboratory data by November 2019. Patients were identified as DBT when DBT was informed as etiology of renal disease or any DBT related ICD10 code was recorded as comorbid condition into the database. Use of insulin, calcitriol, paricalcitol and cinacalcet was also obtained.To evaluate association between DBT and iPTH level, Student t test for independent samples was used. Kruskal-Wallis and Mann-Whitney tests were also performed as confirmatory non-parametric tests for iPTH. Categorical variables were compared using Chi Square test. Linear regression was used to predict iPTH and analyze association with DBT. All procedures were performed on IBM SPSS Statistics© 21. Results A total of 31,709 prevalent patients were included. DBT prevalence was 29.7%. Main differences found between DBT and non-DBT patients are shown in table 1: Linear regression model to predict iPTH showed variables associated with increase in iPTH: Ca, P, K, use of calcitriol, use of cinacalcet; while others were associated with decrease in iPTH: age, dialyzate Ca, Hb, glucose, albumin, use of calcium carbonate as supplementation and DBT (table 2): Conclusion In our population diabetic patients were older, showed higher male prevalence and higher rate of catheter use. Kt/V, Ca and P serum levels were slightly lower than non-diabetic, but not clinically significant.Remarkable differences in laboratory were higher glucose and lower K and alb in DBT. While these differences were expected and already known and well described, lower iPTH in DBT is not.Diabetic disease affects iPTH level independently from other factors increasing the risk for hypoparathyroidism. Those findings should be analyzed to determine if DBT should be considered as a different group when targeting in mineral bone disease or P-binder prescription.

Abstract Background The presence of coinfection and superinfection in hospitalized patients with COVID 19 varies, ranging between 3-14% in case of bacterial coinfection and 3 - 58% for superinfection. The objective of the study is to describe the incidence, type of infection and etiology in a cohort of patients with COVID 19 who required hospitalization. Methods A retrospective series of adult patients with a confirmed diagnosis of COVID 19 who required hospitalization in the general ward or ICU and who presented coinfection or superinfection, between March and November 2020. The clinical and microbiological characteristics of patients who presented coinfection or superinfection are described Results During the study period, 788 patients with COVID 19 who required hospitalization were evaluated. 6.2% presented coinfection, 49 coinfections were documented, 84% detected in patients who required admission to the ICU. The coinfections detected were pneumonia 74%, tracheitis 11%, urinary tract infection 2% and soft tissue infection 2%. Gram negative bacilli were isolated in 58% of cases (K. pneumoniae, H. influenzae, E. cloacae, E. coli), 29% were gram positive (S aureus. S pneumoniae, S. agalactiae). Among gram negative bacilli, 12% showed resistance to 3 generation cephalosporins (3GCephR), no resistance to carbapenems (CR) was found. Superinfection was detected in 18%, with 142 documented infectious events. 98% were hospitalized in the ICU with a mean hospitalization time of 9 days at the time of infection diagnosis. The most frequent infections were tracheitis 49%, pneumonia associated with mechanical ventilation 21%, bloodstream infections 17%, pneumonia 8%, catheter-associated bacteremia 3.6%, urinary tract infection 0.7% and others 0.7%. 80% were gram negative (K. pneumoniae, E. coli, E. cloacae, P. aeruginosa), 16% gram positive and fungi 4% Among the isolated gram negative bacilli, 3% showed 3GCephR and 9% were CR. Table 1.Types of superinfection and microbiological isolation Conclusion The incidence of coinfection in patients with COVID 19 in this series is similar to that reported in the literature. Superinfection occurred in 18% of hospitalized patients, the majority hospitalized in the ICU. 78% of superinfections were from the respiratory tract. Gram-negative bacilli are the most frequently isolated germs in superinfection, with CR of the 9%. Disclosures All Authors: No reported disclosures.

Abstract Background The use of respiratory devices can mitigate the spread of diseases such as COVID-19 in community settings. We aimed to determine the effectiveness of closed face shields with surgical face masks to prevent SARS-CoV-2 transmission in working adults during the COVID-19 pandemic in Bogotá, Colombia. Methods An open-label non-inferiority randomized controlled trial that randomly assigned participants to one of two groups: the intervention group was instructed to wear closed face shields with surgical face masks, and the active control group was instructed to wear only surgical face masks. The primary outcome was a positive reverse transcription polymerase chain reaction test, IgG/IgM antibody test for SARS-CoV-2 detection, or both during and at the end of the follow-up period of 21 days. The non-inferiority limit was established at − 5%. Results A total of 316 participants were randomized, 160 participants were assigned to the intervention group and 156 to the active control group. In total, 141 (88.1%) participants in the intervention group and 142 (91.0%) in the active control group completed the follow-up. Primary outcome: a positive SARS-CoV-2 test result was identified in one (0.71%) participant in the intervention group and three (2.1%) in the active control group. In the intention-to-treat analysis, the absolute risk difference was − 1.40% (95% CI [− 4.14%, 1.33%]), and in the per-protocol analysis, the risk difference was − 1.40% (95% CI [− 4.20, 1.40]), indicating non-inferiority of the closed face shield plus face mask (did not cross the non-inferiority limit). Conclusions The use of closed face shields and surgical face masks was non-inferior to the surgical face mask alone in the prevention of SARS-CoV-2 infection in highly exposed groups. Settings with highly active viral transmission and conditions such as poor ventilation, crowding, and high mobility due to occupation may benefit from the combined use of masks and closed face shields to mitigate SARS-CoV-2 transmission. Trial registration ClinicalTrials.gov NCT04647305. Registered on November 30, 2020

Follicular lymphoma (FL) is the most common type of indolent lymphoma in the Western world, accounting for approximately 30% of lymphoma cases. FL is known for its recurrent nature, necessitating diverse treatment options. The introduction of rituximab, an anti-CD20 antibody, has greatly improved FL outcomes and paved the way for targeted therapies. In this review, we thoroughly explore the structure, mechanism of action, clinical outcomes, and side effects of currently approved monoclonal antibodies (mAb) for FL. Furthermore, we provide insights into ongoing clinical trials and emerging monoclonal antibodies that hold promise for the future of FL treatment. A comprehensive literature search was conducted using various medical databases, including ASH and ASCO publications, as well as PubMed. The clinicaltrials.gov website was used to compile a list of investigational monoclonal antibodies from ongoing clinical trials. The future of antibody-based therapy for follicular lymphoma shows great promise, with a focus on enhancing antibody efficacy, prioritizing optimized combination therapies to address treatment resistance, and evaluating bispecific antibodies as first-line therapies, all while carefully balancing risks and benefits and sequencing treatments appropriately for better disease management. These directions have the potential to establish antibodies as a central component of follicular lymphoma treatment. Article Details How to Cite MOUSTAFA, Muhamad Alhaj. A Comprehensive Review of Monoclonal Antibodies for the Treatment of Follicular Lymphoma Including Both Approved and Investigational Options. Medical Research Archives, [S.l.], v. 11, n. 11, nov. 2023. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/4745>. Date accessed: 02 dec. 2023. doi: https://doi.org/10.18103/mra.v11i11.4745. ABNT APA BibTeX CBE EndNote - EndNote format (Macintosh & Windows) MLA ProCite - RIS format (Macintosh & Windows) RefWorks Reference Manager - RIS format (Windows only) Turabian Issue Vol 11 No 11 (2023): November Issue, Vol.11, Issue 11 Section Research Articles The Medical Research Archives grants authors the right to publish and reproduce the unrevised contribution in whole or in part at any time and in any form for any scholarly non-commercial purpose with the condition that all publications of the contribution include a full citation to the journal as published by the Medical Research Archives. References 1. Swerdlow SH, Campo E, Pileri SA, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016;127(20):2375-2390. doi:10.1182/blood-2016-01-643569 2. Cerhan JR. Epidemiology of Follicular Lymphoma. Hematol Oncol Clin North Am. 2020;34(4):631-646. doi:10.1016/j.hoc.2020.02.001 3. Kaseb H, Ali MA, Koshy NV. Follicular Lymphoma. In: StatPearls. StatPearls Publishing; 2023. Accessed April 8, 2023. http://www.ncbi.nlm.nih.gov/books/NBK538206/ 4. Monga N, Nastoupil L, Garside J, et al. Burden of illness of follicular lymphoma and marginal zone lymphoma. Ann Hematol. 2019;98(1):175-183. doi:10.1007/s00277-018-3501-8 5. Mozas P, Sorigué M, López-Guillermo A. Follicular lymphoma: an update on diagnosis, prognosis, and management. Med Clin (Barc). 2021;157(9):440-448. doi:10.1016/j.medcli.2021.03.041 6. Luminari S, Bellei M, Biasoli I, Federico M. Follicular lymphoma - treatment and prognostic factors. Rev Bras Hematol E Hemoter. 2012;34(1):54-59. doi:10.5581/1516-8484.20120015 7. Illidge T, Chan C. How have outcomes for patients with follicular lymphoma changed with the addition of monoclonal antibodies? Leuk Lymphoma. 2008;49(7):1263-1273. doi:10.1080/10428190802090805 8. Steffanoni S, Ghielmini M, Moccia A. Chemotherapy and treatment algorithms for follicular lymphoma: a look at all options. Expert Rev Anticancer Ther. 2015;15(11):1337-1349. doi:10.1586/14737140.2015.1092386 9. Flowers CR, Leonard JP, Nastoupil LJ. Novel immunotherapy approaches to follicular lymphoma. Hematol Am Soc Hematol Educ Program. 2018;2018(1):194-199. doi:10.1182/asheducation-2018.1.194 10. Marofi F, Rahman HS, Achmad MH, et al. A Deep Insight Into CAR-T Cell Therapy in Non-Hodgkin Lymphoma: Application, Opportunities, and Future Directions. Front Immunol. 2021;12:681984. doi:10.3389/fimmu.2021.681984 11. Bhatt VR, Armitage JO. Autologous and allogeneic hematopoietic stem cell transplantation in follicular lymphoma. Expert Opin Biol Ther. 2016;16(1):57-66. doi:10.1517/14712598.2016.1096341 12. Lin Z, Liu L, Li Z, Xu B. Bispecific antibodies as monotherapy or in combinations for non-hodgkin B-cell lymphoma: latest updates from the American society of hematology 2022 annual meeting. Exp Hematol Oncol. 2023;12(1):41. doi:10.1186/s40164-023-00404-3 13. Coiffier B, Thieblemont C, Van Den Neste E, et al. Long-term outcome of patients in the LNH-98.5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: a study by the Groupe d’Etudes des Lymphomes de l’Adulte. Blood. 2010;116(12):2040-2045. doi:10.1182/blood-2010-03-276246 14. van Meerten T, Hagenbeek A. Novel antibodies against follicular non-Hodgkin’s lymphoma. Best Pract Res Clin Haematol. 2011;24(2):231-256. doi:10.1016/j.beha.2011.03.002 15. Marcus R, Davies A, Ando K, et al. Obinutuzumab for the First-Line Treatment of Follicular Lymphoma. N Engl J Med. 2017;377(14):1331-1344. doi:10.1056/NEJMoa1614598 16. Johnston PB, Bondly C, Micallef INM. Ibritumomab tiuxetan for non-Hodgkin’s lymphoma. Expert Rev Anticancer Ther. 2006;6(6):861-869. doi:10.1586/14737140.6.6.861 17. Gondran C, Ysebaert L. [Drug approval: Mosunetuzumab - third-line therapy in follicular lymphoma]. Bull Cancer (Paris). 2022;109(11):1105-1106. doi:10.1016/j.bulcan.2022.07.010 18. Allen HC, Sharma P. Histology, Plasma Cells. In: StatPearls. StatPearls Publishing; 2023. Accessed April 11, 2023. http://www.ncbi.nlm.nih.gov/books/NBK556082/ 19. Nelson PN, Reynolds GM, Waldron EE, Ward E, Giannopoulos K, Murray PG. Monoclonal antibodies. Mol Pathol MP. 2000;53(3):111-117. doi:10.1136/mp.53.3.111 20. Köhler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 1975;256(5517):495-497. doi:10.1038/256495a0 21. Dunn DL. Monoclonal antibodies for diagnosis and treatment. Arch Surg Chic Ill 1960. 1993;128(11):1274-1280. doi:10.1001/archsurg.1993.01420230102016 22. Posner J, Barrington P, Brier T, Datta-Mannan A. Monoclonal Antibodies: Past, Present and Future. Handb Exp Pharmacol. 2019;260:81-141. doi:10.1007/164_2019_323 23. Di Pauli F, Berger T, Reindl M. Monoclonal antibodies in the treatment of multiple sclerosis. Curr Med Chem. 2009;16(36):4858-4868. doi:10.2174/092986709789909585 24. Lloyd EC, Gandhi TN, Petty LA. Monoclonal Antibodies for COVID-19. JAMA. 2021;325(10):1015. doi:10.1001/jama.2021.1225 25. Kaur N, Goyal A, Sindhu RK. Therapeutic Monoclonal Antibodies in Clinical Practice against Cancer. Anticancer Agents Med Chem. 2020;20(16):1895-1907. doi:10.2174/1871520620666200703191653 26. Yamada T. Therapeutic monoclonal antibodies. Keio J Med. 2011;60(2):37-46. doi:10.2302/kjm.60.37 27. Reff ME, Carner K, Chambers KS, et al. Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20. Blood. 1994;83(2):435-445. 28. Cerny T, Borisch B, Introna M, Johnson P, Rose AL. Mechanism of action of rituximab: Anticancer Drugs. 2002;13:S3-S10. doi:10.1097/00001813-200211002-00002 29. Alas S, Bonavida B. Rituximab inactivates signal transducer and activation of transcription 3 (STAT3) activity in B-non-Hodgkin’s lymphoma through inhibition of the interleukin 10 autocrine/paracrine loop and results in down-regulation of Bcl-2 and sensitization to cytotoxic drugs. Cancer Res. 2001;61(13):5137-5144. 30. Golay J, Zaffaroni L, Vaccari T, et al. Biologic response of B lymphoma cells to anti-CD20 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis. Blood. 2000;95(12):3900-3908. 31. Jacobsen E. Follicular lymphoma: 2023 update on diagnosis and management. Am J Hematol. 2022;97(12):1638-1651. doi:10.1002/ajh.26737 32. Herold M, Haas A, Srock S, et al. Rituximab added to first-line mitoxantrone, chlorambucil, and prednisolone chemotherapy followed by interferon maintenance prolongs survival in patients with advanced follicular lymphoma: an East German Study Group Hematology and Oncology Study. J Clin Oncol Off J Am Soc Clin Oncol. 2007;25(15):1986-1992. doi:10.1200/JCO.2006.06.4618 33. Hiddemann W, Kneba M, Dreyling M, et al. Frontline therapy with rituximab added to the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly improves the outcome for patients with advanced-stage follicular lymphoma compared with therapy with CHOP alone: results of a prospective randomized study of the German Low-Grade Lymphoma Study Group. Blood. 2005;106(12):3725-3732. doi:10.1182/blood-2005-01-0016 34. Marcus R, Imrie K, Belch A, et al. CVP chemotherapy plus rituximab compared with CVP as first-line treatment for advanced follicular lymphoma. Blood. 2005;105(4):1417-1423. doi:10.1182/blood-2004-08-3175 35. Marcus R, Imrie K, Solal-Celigny P, et al. Phase III study of R-CVP compared with cyclophosphamide, vincristine, and prednisone alone in patients with previously untreated advanced follicular lymphoma. J Clin Oncol Off J Am Soc Clin Oncol. 2008;26(28):4579-4586. doi:10.1200/JCO.2007.13.5376 36. Salles G, Mounier N, de Guibert S, et al. Rituximab combined with chemotherapy and interferon in follicular lymphoma patients: results of the GELA-GOELAMS FL2000 study. Blood. 2008;112(13):4824-4831. doi:10.1182/blood-2008-04-153189 37. Colombat P, Salles G, Brousse N, et al. Rituximab (anti-CD20 monoclonal antibody) as single first-line therapy for patients with follicular lymphoma with a low tumor burden: clinical and molecular evaluation. Blood. 2001;97(1):101-106. doi:10.1182/blood.v97.1.101 38. Ghielmini M, Schmitz SFH, Cogliatti SB, et al. Prolonged treatment with rituximab in patients with follicular lymphoma significantly increases event-free survival and response duration compared with the standard weekly x 4 schedule. Blood. 2004;103(12):4416-4423. doi:10.1182/blood-2003-10-3411 39. Witzig TE, Vukov AM, Habermann TM, et al. Rituximab therapy for patients with newly diagnosed, advanced-stage, follicular grade I non-Hodgkin’s lymphoma: a phase II trial in the North Central Cancer Treatment Group. J Clin Oncol Off J Am Soc Clin Oncol. 2005;23(6):1103-1108. doi:10.1200/JCO.2005.12.052 40. Salles G, Seymour JF, Offner F, et al. Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): a phase 3, randomised controlled trial. Lancet Lond Engl. 2011;377(9759):42-51. doi:10.1016/S0140-6736(10)62175-7 41. Martinelli G, Schmitz SFH, Utiger U, et al. Long-term follow-up of patients with follicular lymphoma receiving single-agent rituximab at two different schedules in trial SAKK 35/98. J Clin Oncol Off J Am Soc Clin Oncol. 2010;28(29):4480-4484. doi:10.1200/JCO.2010.28.4786 42. Hanif N, Anwer F. Rituximab. In: StatPearls. StatPearls Publishing; 2023. Accessed April 15, 2023. http://www.ncbi.nlm.nih.gov/books/NBK564374/ 43. Freeman CL, Sehn LH. A tale of two antibodies: obinutuzumab versus rituximab. Br J Haematol. 2018;182(1):29-45. doi:10.1111/bjh.15232 44. Goede V, Klein C, Stilgenbauer S. Obinutuzumab (GA101) for the treatment of chronic lymphocytic leukemia and other B-cell non-hodgkin’s lymphomas: a glycoengineered type II CD20 antibody. Oncol Res Treat. 2015;38(4):185-192. doi:10.1159/000381524 45. Mössner E, Brünker P, Moser S, et al. Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity. Blood. 2010;115(22):4393-4402. doi:10.1182/blood-2009-06-225979 46. Niederfellner G, Lammens A, Mundigl O, et al. Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies. Blood. 2011;118(2):358-367. doi:10.1182/blood-2010-09-305847 47. Suresh T, Lee LX, Joshi J, Barta SK. New antibody approaches to lymphoma therapy. J Hematol OncolJ Hematol Oncol. 2014;7:58. doi:10.1186/s13045-014-0058-4 48. Radford J, Davies A, Cartron G, et al. Obinutuzumab (GA101) plus CHOP or FC in relapsed/refractory follicular lymphoma: results of the GAUDI study (BO21000). Blood. 2013;122(7):1137-1143. doi:10.1182/blood-2013-01-481341 49. Amitai I, Gafter-Gvili A, Shargian-Alon L, Raanani P, Gurion R. Obinutuzumab-related adverse events: A systematic review and meta-analysis. Hematol Oncol. 2021;39(2):215-221. doi:10.1002/hon.2828 50. Riley MB. Ibritumomab tiuxetan. Clin J Oncol Nurs. 2003;7(1):110-112. doi:10.1188/03.CJON.109-112 51. Morschhauser F, Radford J, Van Hoof A, et al. 90Yttrium-ibritumomab tiuxetan consolidation of first remission in advanced-stage follicular non-Hodgkin lymphoma: updated results after a median follow-up of 7.3 years from the International, Randomized, Phase III First-LineIndolent trial. J Clin Oncol Off J Am Soc Clin Oncol. 2013;31(16):1977-1983. doi:10.1200/JCO.2012.45.6400 52. Witzig TE, Flinn IW, Gordon LI, et al. Treatment with ibritumomab tiuxetan radioimmunotherapy in patients with rituximab-refractory follicular non-Hodgkin’s lymphoma. J Clin Oncol Off J Am Soc Clin Oncol. 2002;20(15):3262-3269. doi:10.1200/JCO.2002.11.017 53. Rieger K, De Filippi R, Lindén O, et al. 90-yttrium-ibritumomab tiuxetan as first-line treatment for follicular lymphoma: updated efficacy and safety results at an extended median follow-up of 9.6 years. Ann Hematol. 2022;101(4):781-788. doi:10.1007/s00277-022-04781-3 54. Alhaj Moustafa M, Borah BJ, Moriarty JP, et al. Yttrium-90 Ibritumomab Tiuxetan is Cost-Effective Compared to Bendamustine + Rituximab in Low-grade Lymphomas. Clin Lymphoma Myeloma Leuk. 2023;23(4):259-265. doi:10.1016/j.clml.2023.01.010 55. Salvaris R, Ong J, Gregory GP. Bispecific Antibodies: A Review of Development, Clinical Efficacy and Toxicity in B-Cell Lymphomas. J Pers Med. 2021;11(5):355. doi:10.3390/jpm11050355 56. Budde LE, Sehn LH, Matasar M, et al. Safety and efficacy of mosunetuzumab, a bispecific antibody, in patients with relapsed or refractory follicular lymphoma: a single-arm, multicentre, phase 2 study. Lancet Oncol. 2022;23(8):1055-1065. doi:10.1016/S1470-2045(22)00335-7 57. Jacobson CA, Chavez JC, Sehgal AR, et al. Axicabtagene ciloleucel in relapsed or refractory indolent non-Hodgkin lymphoma (ZUMA-5): a single-arm, multicentre, phase 2 trial. Lancet Oncol. 2022;23(1):91-103. doi:10.1016/S1470-2045(21)00591-X 58. Shimabukuro-Vornhagen A, Gödel P, Subklewe M, et al. Cytokine release syndrome. J Immunother Cancer. 2018;6(1):56. doi:10.1186/s40425-018-0343-9 59. Grigor EJM, Fergusson D, Kekre N, et al. Risks and Benefits of Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in Cancer: A Systematic Review and Meta-Analysis. Transfus Med Rev. 2019;33(2):98-110. doi:10.1016/j.tmrv.2019.01.005 60. Nitschke L. The role of CD22 and other inhibitory co-receptors in B-cell activation. Curr Opin Immunol. 2005;17(3):290-297. doi:10.1016/j.coi.2005.03.005 61. Tang T, Cheng X, Truong B, Sun L, Yang X, Wang H. Molecular basis and therapeutic implications of CD40/CD40L immune checkpoint. Pharmacol Ther. 2021;219:107709. doi:10.1016/j.pharmthera.2020.107709 62. Dakappagari N, Ho SN, Gascoyne RD, Ranuio J, Weng AP, Tangri S. CD80 (B7.1) is expressed on both malignant B cells and nonmalignant stromal cells in non-Hodgkin lymphoma. Cytometry B Clin Cytom. 2012;82(2):112-119. doi:10.1002/cyto.b.20631 63. Deeks ED. Polatuzumab Vedotin: First Global Approval. Drugs. 2019;79(13):1467-1475. doi:10.1007/s40265-019-01175-0 64. Han Y, Liu D, Li L. PD-1/PD-L1 pathway: current researches in cancer. Am J Cancer Res. 2020;10(3):727-742. 65. Rosenbaum CA, Jung SH, Pitcher B, et al. Phase 2 multicentre study of single-agent ofatumumab in previously untreated follicular lymphoma: CALGB 50901 (Alliance). Br J Haematol. 2019;185(1):53-64. doi:10.1111/bjh.15768 66. Hagenbeek A, Gadeberg O, Johnson P, et al. First clinical use of ofatumumab, a novel fully human anti-CD20 monoclonal antibody in relapsed or refractory follicular lymphoma: results of a phase 1/2 trial. Blood. 2008;111(12):5486-5495. doi:10.1182/blood-2007-10-117671 67. Czuczman MS, Fayad L, Delwail V, et al. Ofatumumab monotherapy in rituximab-refractory follicular lymphoma: results from a multicenter study. Blood. 2012;119(16):3698-3704. doi:10.1182/blood-2011-09-378323 68. Morschhauser F, Leonard JP, Fayad L, et al. Humanized anti-CD20 antibody, veltuzumab, in refractory/recurrent non-Hodgkin’s lymphoma: phase I/II results. J Clin Oncol Off J Am Soc Clin Oncol. 2009;27(20):3346-3353. doi:10.1200/JCO.2008.19.9117 69. Morschhauser F, Marlton P, Vitolo U, et al. Results of a phase I/II study of ocrelizumab, a fully humanized anti-CD20 mAb, in patients with relapsed/refractory follicular lymphoma. Ann Oncol Off J Eur Soc Med Oncol. 2010;21(9):1870-1876. doi:10.1093/annonc/mdq027 70. Tobinai K, Ogura M, Kobayashi Y, et al. Phase I study of LY2469298, an Fc-engineered humanized anti-CD20 antibody, in patients with relapsed or refractory follicular lymphoma. Cancer Sci. 2011;102(2):432-438. doi:10.1111/j.1349-7006.2010.01809.x 71. Ganjoo KN, de Vos S, Pohlman BL, et al. Phase 1/2 study of ocaratuzumab, an Fc-engineered humanized anti-CD20 monoclonal antibody, in low-affinity FcγRIIIa patients with previously treated follicular lymphoma. Leuk Lymphoma. 2015;56(1):42-48. doi:10.3109/10428194.2014.911859 72. Leonard JP, Coleman M, Ketas JC, et al. Phase I/II trial of epratuzumab (humanized anti-CD22 antibody) in indolent non-Hodgkin’s lymphoma. J Clin Oncol Off J Am Soc Clin Oncol. 2003;21(16):3051-3059. doi:10.1200/JCO.2003.01.082 73. Advani A, Coiffier B, Czuczman MS, et al. Safety, pharmacokinetics, and preliminary clinical activity of inotuzumab ozogamicin, a novel immunoconjugate for the treatment of B-cell non-Hodgkin’s lymphoma: results of a phase I study. J Clin Oncol Off J Am Soc Clin Oncol. 2010;28(12):2085-2093. doi:10.1200/JCO.2009.25.1900 74. Ogura M, Tobinai K, Hatake K, et al. Phase I study of inotuzumab ozogamicin (CMC-544) in Japanese patients with follicular lymphoma pretreated with rituximab-based therapy. Cancer Sci. 2010;101(8):1840-1845. doi:10.1111/j.1349-7006.2010.01601.x 75. Kebriaei P, Cutler C, de Lima M, et al. Management of important adverse events associated with inotuzumab ozogamicin: expert panel review. Bone Marrow Transplant. 2018;53(4):449-456. doi:10.1038/s41409-017-0019-y 76. Hamadani M, Radford J, Carlo-Stella C, et al. Final results of a phase 1 study of loncastuximab tesirine in relapsed/refractory B-cell non-Hodgkin lymphoma. Blood. 2021;137(19):2634-2645. doi:10.1182/blood.2020007512 77. Salles G, Gopal AK, Minnema MC, et al. Phase 2 Study of Daratumumab in Relapsed/Refractory Mantle-Cell Lymphoma, Diffuse Large B-Cell Lymphoma, and Follicular Lymphoma. Clin Lymphoma Myeloma Leuk. 2019;19(5):275-284. doi:10.1016/j.clml.2018.12.013 78. Fanale M, Assouline S, Kuruvilla J, et al. Phase IA/II, multicentre, open-label study of the CD40 antagonistic monoclonal antibody lucatumumab in adult patients with advanced non-Hodgkin or Hodgkin lymphoma. Br J Haematol. 2014;164(2):258-265. doi:10.1111/bjh.12630 79. Czuczman MS, Thall A, Witzig TE, et al. Phase I/II study of galiximab, an anti-CD80 antibody, for relapsed or refractory follicular lymphoma. J Clin Oncol Off J Am Soc Clin Oncol. 2005;23(19):4390-4398. doi:10.1200/JCO.2005.09.018 80. Armand P, Janssens A, Gritti G, et al. Efficacy and safety results from CheckMate 140, a phase 2 study of nivolumab for relapsed/refractory follicular lymphoma. Blood. 2021;137(5):637-645. doi:10.1182/blood.2019004753 81. Press OW, Unger JM, Braziel RM, et al. Phase II trial of CHOP chemotherapy followed by tositumomab/iodine I-131 tositumomab for previously untreated follicular non-Hodgkin’s lymphoma: five-year follow-up of Southwest Oncology Group Protocol S9911. J Clin Oncol Off J Am Soc Clin Oncol. 2006;24(25):4143-4149. doi:10.1200/JCO.2006.05.8198 82. Leonard JP, Coleman M, Kostakoglu L, et al. Abbreviated chemotherapy with fludarabine followed by tositumomab and iodine I 131 tositumomab for untreated follicular lymphoma. J Clin Oncol Off J Am Soc Clin Oncol. 2005;23(24):5696-5704. doi:10.1200/JCO.2005.14.803 83. Press OW, Unger JM, Rimsza LM, et al. Phase III randomized intergroup trial of CHOP plus rituximab compared with CHOP chemotherapy plus (131)iodine-tositumomab for previously untreated follicular non-Hodgkin lymphoma: SWOG S0016. J Clin Oncol Off J Am Soc Clin Oncol. 2013;31(3):314-320. doi:10.1200/JCO.2012.42.4101 84. Nastoupil LJ, Chin CK, Westin JR, et al. Safety and activity of pembrolizumab in combination with rituximab in relapsed or refractory follicular lymphoma. Blood Adv. 2022;6(4):1143-1151. doi:10.1182/bloodadvances.2021006240 85. Leonard JP, Schuster SJ, Emmanouilides C, et al. Durable complete responses from therapy with combined epratuzumab and rituximab: final results from an international multicenter, phase 2 study in recurrent, indolent, non-Hodgkin lymphoma. Cancer. 2008;113(10):2714-2723. doi:10.1002/cncr.23890 86. Grant BW, Jung SH, Johnson JL, et al. A phase 2 trial of extended induction epratuzumab and rituximab for previously untreated follicular lymphoma: CALGB 50701. Cancer. 2013;119(21):3797-3804. doi:10.1002/cncr.28299 87. Morschhauser F, Flinn IW, Advani R, et al. Polatuzumab vedotin or pinatuzumab vedotin plus rituximab in patients with relapsed or refractory non-Hodgkin lymphoma: final results from a phase 2 randomised study (ROMULUS). Lancet Haematol. 2019;6(5):e254-e265. doi:10.1016/S2352-3026(19)30026-2 88. Diefenbach C, Kahl BS, McMillan A, et al. Polatuzumab vedotin plus obinutuzumab and lenalidomide in patients with relapsed or refractory follicular lymphoma: a cohort of a multicentre, single-arm, phase 1b/2 study. Lancet Haematol. 2021;8(12):e891-e901. doi:10.1016/S2352-3026(21)00311-2 89. Hutchings M, Mous R, Clausen MR, et al. Dose escalation of subcutaneous epcoritamab in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: an open-label, phase 1/2 study. Lancet Lond Engl. 2021;398(10306):1157-1169. doi:10.1016/S0140-6736(21)00889-8 90. Bannerji R, Arnason JE, Advani RH, et al. Odronextamab, a human CD20×CD3 bispecific antibody in patients with CD20-positive B-cell malignancies (ELM-1): results from the relapsed or refractory non-Hodgkin lymphoma cohort in a single-arm, multicentre, phase 1 trial. Lancet Haematol. 2022;9(5):e327-e339. doi:10.1016/S2352-3026(22)00072-2 91. Hutchings M, Morschhauser F, Iacoboni G, et al. Glofitamab, a Novel, Bivalent CD20-Targeting T-Cell-Engaging Bispecific Antibody, Induces Durable Complete Remissions in Relapsed or Refractory B-Cell Lymphoma: A Phase I Trial. J Clin Oncol Off J Am Soc Clin Oncol. 2021;39(18):1959-1970. doi:10.1200/JCO.20.03175 92. Subklewe M. BiTEs better than CAR T cells. Blood Adv. 2021;5(2):607-612. doi:10.1182/bloodadvances.2020001792 93. Tapia-Galisteo A, Compte M, Álvarez-Vallina L, Sanz L. When three is not a crowd: trispecific antibodies for enhanced cancer immunotherapy. Theranostics. 2023;13(3):1028-1041. doi:10.7150/thno.81494 94. Wu L, Seung E, Xu L, et al. Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation. Nat Cancer. 2020;1(1):86-98. doi:10.1038/s43018-019-0004-z 95. Yao Y, Hu Y, Wang F. Trispecific antibodies for cancer immunotherapy. Immunology. 2023;169(4):389-399. doi:10.1111/imm.13636 96. Fayad L, Offner F, Smith MR, et al. Safety and clinical activity of a combination therapy comprising two antibody-based targeting agents for the treatment of non-Hodgkin lymphoma: results of a phase I/II study evaluating the immunoconjugate inotuzumab ozogamicin with rituximab. J Clin Oncol Off J Am Soc Clin Oncol. 2013;31(5):573-583. doi:10.1200/JCO.2012.42.7211 97. Kolstad A, Illidge T, Bolstad N, et al. Phase 1/2a study of 177Lu-lilotomab satetraxetan in relapsed/refractory indolent non-Hodgkin lymphoma. Blood Adv. 2020;4(17):4091-4101. doi:10.1182/bloodadvances.2020002583 98. Palomba ML, Till BG, Park SI, et al. Combination of Atezolizumab and Obinutuzumab in Patients with Relapsed/Refractory Follicular Lymphoma and Diffuse Large B-Cell Lymphoma: Results from a Phase 1b Study. Clin Lymphoma Myeloma Leuk. 2022;22(7):e443-e451. doi:10.1016/j.clml.2021.12.010 99. Morschhauser F, Ghosh N, Lossos IS, et al. Obinutuzumab-atezolizumab-lenalidomide for the treatment of patients with relapsed/refractory follicular lymphoma: final analysis of a Phase Ib/II trial. Blood Cancer J. 2021;11(8):147. doi:10.1038/s41408-021-00539-8 100. Czuczman MS, Hess G, Gadeberg OV, et al. Chemoimmunotherapy with ofatumumab in combination with CHOP in previously untreated follicular lymphoma. Br J Haematol. 2012;157(4):438-445. doi:10.1111/j.1365-2141.2012.09086.x 101. Westin JR, Chu F, Zhang M, et al. Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial. Lancet Oncol. 2014;15(1):69-77. doi:10.1016/S1470-2045(13)70551-5 102. Czuczman MS, Leonard JP, Jung S, et al. Phase II trial of galiximab (anti-CD80 monoclonal antibody) plus rituximab (CALGB 50402): Follicular Lymphoma International Prognostic Index (FLIPI) score is predictive of upfront immunotherapy responsiveness. Ann Oncol Off J Eur Soc Med Oncol. 2012;23(9):2356-2362. doi:10.1093/annonc/mdr620

Scores of farm workers on hunger strike in the US. A campaigner for affordable housing abducted in Cape Town. Tens of thousands of anti-war demonstrators marching in Istanbul. None of those stories made my daily paper — instead, I read them all this morning on the global Indymedia network. Developments in communication technologies have often enabled new approaches to the production, distribution and reception of news. In this article, using Carey’s analysis of the impacts of the telegraph (1989) and Burnett and Marshall’s discussion of “informational news” (2003) as starting points, I want to offer some examples from the brief history of the Indymedia movement to show how the Net is making possible a significant shift in who gets to make the news. The telegraph offers a number of useful perspectives from which to consider the impacts of the Net, and there are some striking parallels between the dot.com boom of the 1990s and the dot.dash boom of the 19th century. Telegraphy, writes James Carey, “permitted for the first time the effective separation of communication from transportation” (203). The telegraph was not only an instrument of business, but “a thing to think with, an agency for the alteration of ideas” (204). And a consideration of the telegraph offers a number of examples of the relationships between technological form and the nature of news. One such example, in Carey’s analysis, was the impact of the telegraph on the language and nature of journalism. “If the same story were to be understood in the same way from Maine to California,” he writes, “language had to be flattened out and standardised” (210). Local colour was bleached out of news reports to make them saleable in a market unconstrained by geography. “The origins of objectivity,” Carey argues, “may be sought, therefore, in the necessity of stretching language in space over the long lines of Western Union” (210). The telegraph didn’t just affect the quality of news — it greatly increased the quantity of it as well, forcing greater attention to be paid to the management of newsrooms. News became a commodity; not only that, just like cattle or wheat, news was now subject to all the vagaries of any other commodity business, from contracts and price gouging to outright theft (211). And in Western Union, the telegraph made possible the prototype of today’s transnational media firms (201). As the telegraph solved problems of communicating across space, it opened up time as a new arena for expansion. In this sense, the gradual emergence of 24-hour broadcasting schedules is traceable to the impact of the telegraph (Carey 228). A key legacy of this impact is the rise to primacy of CNN and its imitators, offering round-the-clock news coverage made possible by satellite transmission. This too changed the nature of news. As McKenzie Wark has pointed out, a 24-hour continuous news service is not ideally compatible with the established narrative strategies of news. Rather than cutting and shaping events to fit familiar narrative forms, CNN instead introduced an emphasis on what Wark calls “the queer concept of ‘live’ news coverage — an instant audiovisual presence on the site of an event” (38). This focus on speed and immediacy, on being the first on the scene, leads to news that is all event and no process. More than this, it leads at times to revealing moments when CNN-style coverage becomes obvious as a component part of the event it purports to cover. In his analysis of the Tiananmen Square crisis of 1989 Wark argues that the media event appeared as “a positive feedback loop” (22). The Beijing students’ perceptions of Western accounts of their demands and motives became caught up in the students’ own accounts of their own motives, their own demands: Western interpretations of what was happening in Beijing, Wark writes, “fed back into the event itself via a global loop encompassing radio, telephone, and fax vectors. They impacted back on the further unfolding of the event itself” (22). Both the telegraph and the satellite contributed to major shifts in the production, distribution and reception of news. And both made possible new types of media institution, from Western Union and Reuters to CNN. This is not to argue that technologies determine the nature of news or of news organisations, but rather that certain developments are made possible by both the adoption and the adaptation of new technologies. Institutional and cultural factors, of course, affect the nature of news, but technology also both enables and constrains. The medium might not be the message — but it does matter. So with such precedents as those above in mind, what might be the key impacts of the Net on the nature of news? In an important analysis of the online news environment, Robert Burnett and P. David Marshall introduce the concept of “informational news,” defined as “the transformation of journalism and news in Web culture where there is a greater involvement of the user and news hierarchies are in flux” (206). News, they argue, has become “a subset of a wider search for information by Web users” (206) and this “has led to a shift in how we recontextualise news around a much larger search for information” (152). In this analysis, audience members are transformed into researchers. These researchers become comfortable with getting their news from a broader range of sources, while at the same time searching for new ways to hierarchise those sources, to establish some as more legitimate than others. Adding to the complexity are Burnett and Marshall’s observations that new media forms offer enhanced flexibility (with, for example, archival access to news databases, including audio and video, available 24 hours a day), and that online news fosters and caters for new global communities of interest 161-7). When these phenomena are taken together, the result for Burnett and Marshall is “a shifted boundary of what constitutes news” (167). But this concept of informational news is largely cast in terms of reception and consumption: the practices of the new informational news researchers are discussed in terms of information retrieval, not production — even newsgroups and Weblogs are considered as additional sources for information retrieval, rather than as new avenues for new kinds of journalists to develop and publish new kinds of news. Burnett and Marshall are, I believe, right in their identification of changes to the nature of news, and their analysis is an important contribution. But what I want to emphasise in this article is that there is also a corresponding ongoing shift in the boundary of what constitutes newsmakers. The Indymedia movement offers clear examples of this, in its spectacular growth and in its promotion of open publishing models. As a forum for non-professional journalists of all stripes, Indymedia’s development is a vivid example of the shifting boundary around who gets to make the news. By now, many readers of M/C will perhaps be familiar with Indymedia to some degree. But it’s worth briefly reviewing both the scope of the movement and the speed with which it’s developed. The first Indymedia Website was established for the Seattle demonstrations against the World Trade Organisation meeting in November 1999. Its key feature was offering news coverage supplied by anyone who wanted to contribute, using free software and ideas from the Australian activists who had created the Active network. As events in Seattle gathered pace, the nascent Indymedia drew a claimed 1.5 million hits; this success led to the site being refocussed around several subsequent protests, before local collectives began to appear and form their own Indymedia centres. Within a year, this original Indymedia site was just one of a new network of more than 30. At the time of writing, a little over three years on from the movement’s inception, there are more than 100 Indymedia centres around the world — there are both Israeli and Palestinian Indymedia; Indymedia is established in Mumbai, Jakarta and Buenos Aires; there are centres in Poland, Colombia and South Africa. By any measure, this is a remarkable achievement for a decentralised project run entirely by volunteers and donations. Like any other complex phenomenon, the story of this development can be told in many different ways, each adding a different dimension. Three are especially relevant here. The first version would centre around the Active software developed by Sydney’s Catalyst tech collective. This was devised to create the Active Sydney site, an online hub for Sydney activists to promote events from direct actions to screenings and seminars. Launched in January 1999, Active Sydney was to become a prototype for Indymedia — part events calendar, part meeting place, part street paper. For June of that year, the Active team revised the system for the J18 global day of action. Using this system, anyone could now upload a report, a video clip, a photo or an audio file, and see it instantly added to the emerging narrative of events. It was as easy as sending email. And it ran on open source code. With Catalyst members collaborating online with organisers in Seattle to establish the first site, this system became the basis for Indymedia. While the Active software is no longer the only platform used for Indymedia sites, it made a huge contribution to the movement’s explosive growth (see Arnison, 2001; Meikle, 2002). Another version of the story would place Indymedia within the long traditions of alternative media. John Downing’s work is important here, and his definition of “politically dissident media that offer radical alternatives to mainstream debate” is useful (240). To tell the Indymedia story from this perspective would be to highlight its independence and self-management, and the autonomy of each local editorial collective in running each Indymedia centre. It would be to emphasise Indymedia as a forum for viewpoints which are not usually expressed within the established media’s consensus about what is and isn’t news. And, perhaps most importantly, to tell the Indymedia story as one in the alternative media tradition would be to focus on the extent to which this movement fosters horizontal connections and open participation, in contrast to the vertical flows of the established broadcast and print media (Downing, 1995). A third version would approach Indymedia as part of what cultural studies academic George McKay terms “DiY Culture.” McKay defines this as “a youth-centred and -directed cluster of interests and practices around green radicalism, direct action politics, new musical sounds and experiences”(2). For this version of the story, a useful analogy would be with punk — not with the music so much as with its DIY access principle (“here’s three chords, now form a band”). DIY was the key to Richard Hell’s much-misunderstood lyric “I belong to the blank generation” — the idea of the blank was that you were supposed to fill it in for yourself, rather than sign up to someone else’s agenda. To consider Indymedia as part of this DIY spirit would be to see it as the expression of a blank generation in this fine original sense — not a vacant generation, but one prepared to offer their own self-definitions and to create their own media networks to do it. More than this, it would also be to place Indymedia within the frameworks of independent production and distribution which were the real impact of punk — independent record labels changed music more than any of their records, while photocopied zines opened up new possibilities for self-expression. Just as the real importance of punk wasn't in the individual songs, the importance of Indymedia isn't in this or that news story posted to this or that site. Instead, it's in its DIY ethos and its commitment to establishing new networks. What these three versions of the Indymedia story share is that each highlights an emphasis on access and participation; each stresses new avenues and methods for new people to create news; each shifts the boundary of who gets to speak. And where these different stories intersect is in the concept of open publishing. This is the Net making possible a shift in the production of news, as well as in its reception. Matthew Arnison of Catalyst, who played a key role in developing the Active software, offers a working definition of open publishing which is worth quoting in full: “Open publishing means that the process of creating news is transparent to the readers. They can contribute a story and see it instantly appear in the pool of stories publicly available. Those stories are filtered as little as possible to help the readers find the stories they want. Readers can see editorial decisions being made by others. They can see how to get involved and help make editorial decisions. If they can think of a better way for the software to help shape editorial decisions, they can copy the software because it is free and change it and start their own site. If they want to redistribute the news, they can, preferably on an open publishing site.” (Arnison, 2001) Open publishing has undoubtedly been a big part of the appeal of Indymedia for its many contributors. In fact, one of Indymedia’s slogans is “everyone is a journalist.” If this is a provocation, who and what is it meant to provoke? Obviously, “everyone” is not a journalist — at least not if journalists are seen as employees of news institutions and news businesses, employees with some kind of training in research methods and narrative construction. But to say that “everyone is a journalist” is not to claim that everyone has such institutional affiliation, or that everyone has such training or expertise. Instead, the tactic here seems to be to inflate something out of all proportion in order to draw attention to the core smaller truth that may otherwise go unnoticed. Specifically in this case, what authorises some to be story-tellers and not others? From this perspective, the slogan reads like a claim for difference, a claim that other kinds of expertise and other kinds of know-how also have valid claims on our attention, and that these too can make valid contributions to the more plural media environment made possible — but not guaranteed — by the Net. It’s a claim that the licence to tell stories should be shared around. But developments to this core element — open publishing — point both to an ongoing challenge for the Indymedia movement, and to a possible future which might enable a further significant shift in the nature of Net news. In March 2002, a proposal was circulated to remove the open publishing newswire from the front page of the main site at http://www.indymedia.org/, replacing this with features sourced from local sites around the world. While this was said to have the objective of promoting those local sites to a broader audience, it should also be seen as acknowledgement that Indymedia was struggling against limits to growth. One issue was the large number of items being posted to sites, which meant that even especially well-researched or significant stories would be replaced quickly on the front page; another issue was the persistent trolls and spam which plagued some Indymedia sites. In April 2002, after a voting process in which 15 Indymedia collectives from Brazil to Barcelona voted unanimously in favour of the reform, the open publishing newswire was taken off the front page. Many local Indymedia sites followed suit. Even the Sydney site, which, perhaps because of the history and involvement of the Catalyst group, promotes open publishing rather more than some other Indymedia sites, adopted a features-based front page in August 2002, stating that “promoting certain issues above others” would make the site “more effective.” These developments might signal the eventual demise of the open publishing component. Indymedia might instead become ‘professionalised,’ with greater reliance on de facto staff reporters and more stringent editing, moving closer to existing alternative media outlets. But the new centrality of its news features might also open Indymedia up to a new level of involvement, because those features are given prominence in the site’s central column and can remain on the front page for some weeks. This offers the potential for what Arnison terms “automated open-editing”. This would involve creating the facility for audience members to contribute to sub-editing stories on an Indymedia site: they might, for instance, check facts or add sources; edit spelling, grammar or formatting; nominate a topic area within which a given story could be archived; or translate the story from one language or style to another (Arnison, 2001). Open publishing is one phenomenon in which we can see the Net enabling changes to the nature of news and newsmakers. If open editing were also to work, then it would need to be as simple to operate as the original open publishing newswire. But if this were possible, then open editing might involve not only more new people in the development of informational news, but involve them in new ways, catering for a broader range of abilities and aptitudes than open publishing alone. Like earlier communication technologies, the Net could facilitate new types of media institution — ones built on an open model, which enable a new, more plural, news environment. Works Cited Arnison, Matthew. “Open Publishing Is the Same as Free Software.” 2001. 21 Feb. 2003 <http://www.cat.org.au/maffew/cat/openpub.php>. Arnison, Matthew. “Open Editing: A Crucial Part of Open Publishing.” 2002. 21 Feb. 2003 <http://www.cat.org.au/maffew/cat/openedit.php>. Burnett, Robert, and P. David Marshall. Web Theory: An Introduction. London & New York: Routledge, 2003. Carey, James. Communication as Culture. New York & London: Routledge, 1989. Downing, John. “Alternative Media and the Boston Tea Party.” Questioning The Media. Eds. John Downing, Ali Mohammadi and Annabelle Sreberny-Mohammadi. Thousand Oaks: Sage, 1995. 238-52. McKay, George. “DiY Culture: Notes towards an Intro.” DiY Culture: Party & Protest in Nineties Britain. Ed. George McKay. London: Verso, 1998. 1-53. Meikle, Graham. Future Active: Media Activism and the Internet. New York & London: Routledge, and Annandale: Pluto Press, 2002. Wark, McKenzie. Virtual Geography: Living with Global Media Events. Bloomington: Indiana UP, 1994. Links http://www.cat.org.au/maffew/cat/openedit.html http://www.cat.org.au/maffew/cat/openpub.html http://www.indymedia.org/ http://www.sydney.active.org.au/ Citation reference for this article Substitute your date of access for Dn Month Year etc... MLA Style Meikle, Graham. "Indymedia and The New Net News" M/C: A Journal of Media and Culture< http://www.media-culture.org.au/0304/02-feature.php>. APA Style Meikle, G. (2003, Apr 23). Indymedia and The New Net News. M/C: A Journal of Media and Culture, 6,< http://www.media-culture.org.au/0304/02-feature.php>

This article analyses the public persona of Jeremy Gilley, a documentary filmmaker, peace campaigner, and the founder of the organisation Peace One Day (POD). It begins by outlining how Gilley’s persona is presented in a manner which resonates with established archetypes of social campaigners, and how this creates POD’s legitimacy among grassroots organisations. I then describe a distinct, but not inconsistent, facet of Gilley’s persona which speaks specifically to entrepreneurs. The article outlines how Gilley’s individuality works to simultaneously address these overlapping audiences and argues that his persona can be read as an articulation of social entrepreneurship. Gilley represents an example of a public personality working to “crystallise issues and to normativise debates” (Marshall “Personifying” 370) concerning corporate involvement with non-profit organisations and the marketisation of the non-profit sector. Peace One Day (POD) is a UK-based non-profit organisation established in 1999 by actor-turned-documentary-filmmaker Jeremy Gilley. In the 1990s, while filming a documentary about global conflict, Gilley realised there was no internationally recognised day of ceasefire and non-violence. He created POD to found such a day and began lobbying the United Nations. In 2001, the 111th plenary meeting of the General Assembly passed a resolution which marked 21 September as the annual International Day of Peace (United Nations). Since 2001, POD has worked to create global awareness of Peace Day. By 2006, other NGOs began using the day to negotiate 24-hour ceasefires in various conflict zones, allowing them to carry out work in areas normally too dangerous to enter. For example, in 2007, the inoculation of 1.3 million Afghan children against polio was possible due to an agreement from the Taliban to allow safe passage to agencies working in the country during the day. This was repeated in subsequent years and, by 2009, 4.5 million children had been immunised (POD Part Three). While neither POD nor Gilley played a direct part in the polio vaccination programmes or specific ceasefires, his organisation acted as a catalyst for such endeavours and these initiatives would not have occurred without POD’s efforts.Gilley is not only the founder of POD, he is also the majority shareholder, key decision-maker, and predominant public spokesperson in this private, non-charitable, non-profit organisation (Frances 73). While POD’s celebrity supporters participate in press conferences, it is Gilley who does most to raise awareness. His public persona is inextricably linked with POD and is created through a range of presentational media with which he is engaged. These include social media content, regular blogposts on POD’s website, as well as appearances at a series of speaking events. Most significantly, Gilley establishes his public persona through a number of documentary films (Peace One Day; Day After; POD Part Three), which are shot largely from his perspective and narrated by his voiceover, and which depict POD’s key struggles and successes.The Peace Campaigner as an Activist and Entrepreneur In common with other non-profit organisations, POD relies on celebrities from the entertainment industries. It works with them in two key ways: raising the public profile of the organisation, and shaping the public persona of its founder by inviting comparisons of their perceived exceptionalness with his ostensible ordinariness. For example, Gilley’s documentaries depict various press conferences held by POD over a number of years. Those organised prior to POD recruiting celebrity spokespeople were “completely ignored by the media” whereas those held after celebrity backing from Jude Law and Angelina Jolie had been secured attracted considerable interest (Day After). Gilley explains his early difficulties in publicising his message by suggesting that he “was a nobody” (POD Part Three). This representation as a “nobody” or, more diplomatically, as “ordinary,” is a central component of Gilley’s persona. “Ordinariness” here means situating Gilley outside the political and entertainment elites and aligning him with more everyday suburban settings. This is done through a combination of the aesthetic qualities of his public presentation and his publically narrated back-story.Aesthetically speaking, Gilley presents his ordinariness through his casual attire and long hair. His appearance is similar to the campaigners, youth groups and school children he addresses, suggesting he is a representative of that demographic but also distancing him from political elites. The diplomats Gilley meets, such as those at the UN, wear the appropriate attire for their elite political setting: suits. In one key scene in the documentary Peace One Day, Gilley makes his first trip to the UN to meet Kofi Annan, UN General Secretary at the time, and appears at their doors clean cut and suitably dressed. He declares that his new appearance was designed to aid his credibility with the UN. Yet, at the same time, he makes explicit that he borrowed the suit from a friend and the tie from his grandfather and, prior to the meeting, it was decided, “the pony tail had to go.” Thus Gilley seeks the approval of both political elites and the ordinary public, and constructs a persona that speaks to both, though he aligns himself with the latter.Gilley’s back-story permeates his films and works to present his ordinariness. For example, POD has humble beginnings as an almost grassroots, family-run organisation, and Gilley depicts a campaign run on a shoestring from his mother’s spare bedroom in an ordinary suburban home. Although British Airways provided free flights from the organisation’s outset, Gilley shows his friends volunteering their time by organising fundraising events. POD’s modest beginnings are reflected in its founder, who confides about both his lack of formal education and lack of success as an actor (Day After). This “ordinariness” is constructed in opposition to the exceptional qualities of POD’s A-list celebrity backers—such as Angelina Jolie, who does enjoy success as an actor. This contrast is emphasised by inviting Jolie into Gilley’s everyday domestic setting and highlighting the icons of success she brings with her. For example, at his first meeting with Jolie, Gilley waits patiently for her and remarks about the expensive car which eventually arrives outside his house, denoting Jolie’s arrival. He notes in the voiceover to his The Day after Peace documentary, “this was unbelievable, Angelina Jolie sat on my sofa asking me what she could do, I couldn’t stop talking. I was so nervous.”Gilley promotes his ordinariness by using aesthetics and personal narrative. Evidence of how he struggled to realise his goals and the financial burdens he carried (Peace One Day) suggest that there is something authentic about Gilley’s vision for Peace Day. This also helps Gilley to align his public persona with common understandings of the political activist as a prophetic social visionary. POD is able to tap into the idea of the power of the individual as a force for change with references to Martin Luther King and Gandhi. Although Gilley makes no direct comparison between himself and these figures, blog entries such as “ten years ago, I had an idea; I dared to dream that I could galvanise the countries of the world to recognise an official day of ceasefire and nonviolence. Mad? Ambitious? Idealistic? All of the above” (Gilley “Dream”), invite comparisons with King’s “I Have a Dream” speech. This is further augmented by references to Gilley as an outsider to political establishments, such as the UN, which he is sure have “become cynical about the opportunity” they have to unite the world (BBC Interview).Interestingly, Gilley’s presentation as a pragmatic “change-maker” whose “passion is contagious” (Ahmad Fawzi, in POD Concert) also aligns him with a second figure: the entrepreneur. Where Gilley’s performances at school and community groups present his persona as an activist, his entrepreneur persona is presented through his performances at a series of business seminars. These seminars, entitled “Unleash Your Power of Influence,” are targeted towards young entrepreneurs and business-people very much consistent with the “creative class” demographic (Florida). The speakers, including Gilley, have all been successful in business (POD is a private company) and they offer to their audiences motivational presentations, and business advice. Although a semi-regular occurrence, it is the first two events held in July 2010 (Unleash 1) and November 2010 (Unleash 2) that are discussed here. Held in a luxury five-star London hotel, the events demonstrate a starkly different aspect of POD than that presented to community groups and schools, and the amateur grassroots ethic presented in Gilley’s documentary films—for example, tickets for Unleash 2 started at £69 and offered ‘goody bags’ for £95 (author’s observation of the event)—yet consistencies remain.Aesthetically speaking, Gilley’s appearance signifies a connection with these innovative, stereotypically young, founders of start-up companies and where Gilley is an outsider to political organisations; they are outsiders to business establishments. Further, many of these companies typically started, like POD, in a spare bedroom. The speakers at the Unleash events provide insights into their background which frequently demonstrate a rise from humble beginnings to business success, in the face of adversity, and as a result of innovation and perseverance. Gilley is not out of place in this environment and the modest beginnings of POD are relayed to his audience in a manner which bears a striking similarity to his for-profit counterparts.An analysis of Gilley’s presentations at these events demonstrates clear links between the dual aspects of Gilley’s public persona, the political economy of POD, and the underlying philosophy of the organisation—social entrepreneurship. The next section sets out some of the principals of social entrepreneurship and how the aspects of Gilley’s persona, outlined above, reinforce these.Personifying Social EnterpriseGenerally speaking, the business literature greatly emphasises entrepreneurs as “resourceful, value-creating change agents” who are “never satisfied with the status quo [... and are] a forceful engine of growth in our economy” (Dees and Economy 3-4). More recently, the focus of discussion has included social entrepreneurs. These individuals work within “an organisation that attacks [social and environmental] problems through a business format, even if it is not legally structured as a profit-seeking entity” (Bornstein and Davis xv) and advocate commercially oriented non-profit organisations that establish “win-win” relationships between non-profits and business.This coming together of the for- and non-profit sectors has range of precedents, most notably in “philanthrocapitalism” (Bishop and Green) and the types of partnerships established between corporations and environmentalists, such as Greenpeace Australia (Beder). However, philanthrocapitalism often encompasses the application of business methods to social problems by those who have amassed fortunes in purely commercial ventures (such as Bill Gates), and Beder’s work describes established for- and non-profit institutions working together. While social entrepreneurship overlaps with these, social entrepreneurs seek to do well by doing good by making a profit while simultaneously realising social goals (Bornstein and Davis 25).Read as an articulation of the coming together of the activist and the entrepreneur, Gilley’s individuality encapsulates the social enterprise movement. His persona draws from the commonalities between the archetypes of the traditional grassroots activist and start-up entrepreneur, as pioneering visionary and outsider to the establishment. While his films establish his authenticity among politically attuned members of the public, his appearances at the Unleash events work to signify the legitimacy of his organisation to those who identify with social entrepreneurialism and take the position that business should play a positive role in social causes. As an activist, Gilley’s creates his persona through his aesthetic qualities and a performance that draws on historical precedents of social prophets. As an entrepreneur, Gilley draws on the same aesthetic qualities and, through his performance, mitigates the types of disjuncture evident in the 1980s between environmental activists, politicians and business leaders, when environmentalist’s narratives “were perceived as flaky and failed to transform” (Robèrt 7). To do this, Gilley reconstitutes social and environmental problems (such as conflict) within a market metric, and presents the market as a viable and efficient solution. Consequently, Gilley asserts that “we live in a culture of war because war makes money, we need to live in a culture of peace,” and this depends on “if we can make it economical, if we can make the numbers add up” (Unleash).Social enterprises often eschew formal charity and Gilley is consistent with this when he states that “for me, I think it has to be about business. [...] I think if it’s about charity it’s not going to work for me.” Gilley asserts that partnerships with corporations are essential as “our world is going to change, when the corporate sector becomes engaged.” He, therefore, “want[s] to work with large corporations” in order to “empower individuals to be involved in the process of [creating] a more peaceful and sustainable world” (Unleash). One example of POD’s success in this regard is a co-venture with Coca-Cola.To coincide with Peace Day in 2007, POD and Coca-Cola entered into a co-branding exercise which culminated in a sponsorship deal with the POD logo printed on Coca-Cola packaging. Prior to this, Gilley faced a desperate financial situation and conceded that the only alternative to a co-venture with Coca-Cola was shutting down POD (Day After). While Coca-Cola offered financial support and the potential to spread Gilley’s message through the medium of the Coke can, POD presumably offered good publicity to a corporation persistently the target of allegations of unethical practice (for example, Levenson-Estrada; Gill; Thomas). Gilley was aware of the potential image problems caused by a venture with Coke but accepted the partnership on pragmatic grounds, and with the proviso that Coke’s sponsorship not accompany any attempt to influence POD. Gilley, in effect, was using Coca-Cola, displaying the political independence of the social visionary and the pragmatism of the entrepreneur. By the same token, Coca-Cola was using POD to garner positive publicity, demonstrating the nature of this “win-win” relationship.In his film, Gilley consults Ray C. Anderson, social enterprise proponent, about his ethical concerns. Anderson explains the merits of working with Coke. In his Unleash addresses, such ethical considerations do not feature. Instead, it is relayed that Coca-Cola executives were looking to become involved with a social campaign, consistent with the famous 1970s hilltop advertisement of “teaching the world to sing in harmony.” From a meeting at Coca-Cola’s headquarters in Atlanta, Gilley reveals, a correlation emerged between Gilley’s emphasis on Peace Day as a moment of global unity—encapsulated by his belief that “the thing about corporations [...] the wonderful thing about everybody […] is that everybody’s just like us” (Unleash)—and the image of worldwide harmony that Coca-Cola wanted to portray. It is my contention that Gilley’s public persona underpinned the manner in which this co-branding campaign emerged. This is because his persona neatly tied the profit motive of the corporation to the socially spirited nature of the campaign, and spoke to Coca-Cola in a manner relatable to the market. At the same time, it promoted a social campaign premised on an inclusiveness that recast the corporation as a concerned global citizen, and the social campaigner as a free-market agent.Persona in the Competitive Non-Profit SectorThrough a series of works P. David Marshall charts the increasing centrality of individuality as “one of the ideological mainstays of consumer capitalism [...and] equally one of the ideological mainstays of how democracy is conceived” (Marshall “New Media-New Self” 635). Celebrity, accordingly, can be thought of as a powerful discourse that works “to make the cultural centrality of individuality concretely real” (Marshall “New Media-New Self” 635). Beyond celebrity, Marshall offers a wider framework that maps how “personalisation, individuality, and the move from the private to the public are now part of the wider populace rather than just at play in the representational field of celebrity” (Marshall, “Persona” 158). This framework includes fundamental changes to the global, specifically Western, labour market that, while not a fait accompli, point to a more competitive environment in which “greater portions of the culture are engaged in regular—probably frequent—selling of themselves” and where self-promotion becomes a key tool (Marshall, “Persona” 158). Therefore, while consumerism comprises a backdrop to the proliferation of celebrity culture, competition within market capitalism contributes to the wider expansion of personalisation and individualism.The non-profit sector is also a competitive environment. UK studies have found an increase in the number of International NGOs of 46.6% from 1995/6-2005/6 (Anheier, Kaldor, and Glasius. 310). At the same time, the number of large charities (with an income greater than £10 million) rose, between 1999-2013, from 307 to 1,005 and their annual income rose from approximately £10bn to £36bn (Charity Commission). These quantitative changes in the sector have occurred alongside qualitative changes in terms of the orientation of individual organisations. For example, Epstein and Gang describe a non-profit sector in which NGOs compete against each other for funds from aid donors (state and private). It is unclear whether “aid will be allocated properly, say to the poorest or to maximize the social welfare” or to the “efficient aid-seekers” (294)—that is, NGOs with the greatest competitive capabilities. A market for public awareness has also emerged and, in an increasingly crowded non-profit sector, it is clearly important for organisations to establish a public profile that can gain attention.It is in this competitive environment that the public personae of activists become assets for NGOs, and Gilley constitutes a successful example of this. His persona demonstrates an organisation’s response to the competitive nature of the non-profit sector, by appealing to both traditional activist circles and the business sector, and articulating the social enterprise movement. Gilley effectively embodies social entrepreneurship—in his appearance, his performance and his back-story—bridging a gap between the for- and non-profit sectors. His persona helps legitimate efforts to recast the activist as an entrepreneur (and conversely, entrepreneurs as activists) by incorporating activist ideals (in this instance, peace) within a market framework. This, to return to Marshall’s argument, crystallises the issue of peace within market metrics such and normativises debates about the role of corporate actors as global citizens, presenting it as pragmatism and therefore “common sense.” This is not to undermine Gilley’s achievements but, instead, to point out how reading his public persona enables an understanding of efforts to marketise the non-profit sector and align peace activism with corporate power.References Anheier, Helmut K., Mary Kaldor, and Marlies Glasius. Global Civil Society 2006/7. London: Sage, 2007.BBC Storyville. Director Interview: Jeremy Gilley. BBC. 2004. 7 Feb. 2010.Beder, Sharon. Global Spin: The Corporate Assault on Environmentalism. Totnes, UK: Green Books, 2002.Bishop, Matthew, and Michael Green. Philanthrocapitalism. London: A&C Black, 2008.Bornstein, David, and Susan Davis. Social Entrepreneurship: What Everyone Needs to Know. New York: Oxford University Press, 2010.Charity Commission for England and Wales. “Sector Facts and Figures.” N.d. 5 Apr 2014.Day after Peace, The. Dir. Jeremy Gilley. Peace One Day, 2008.Dees, J. Gregory, and Peter Economy. "Social Entrepreneurship." Enterprising Nonprofits: A Toolkit for Social Entrepreneurs. Eds. J. Gregory Dees, Jed Emerson, and Peter Economy. New York: Wiley, 2001. 1-18.Epstein, Gil S., and Ira N. Gang. “Contests, NGOs, and Decentralizing Aid.” Review of Development Economics 10. 2 (2006): 285-296.Florida, Richard. The Flight of the Creative Class: The New Global Competition for Talent. New York: Harper Business, 2006.Frances, Nic. The End of Charity: Time for Social Enterprise. New South Wales: Allen & Unwin, 2008.Fraser, Nick. “Can One Man Persuade the World, via the UN, to Sanction a Global Ceasefire Day?” BBC. 2005. 7 Feb. 2010.Gill, Leslie. “Labor and Human Rights: The ‘Real Thing’ in Colombia.” Transforming Anthropology 13.2 (2005): 110-115.Gilley, Jeremy. “Dream One Day.” Peace One Day. 2009. 23 Jun 2010.Levenson-Estrada, Deborah. Trade Unionists against Terror: Guatemala City, 1954-1985. Chapel Hill: U of North Carolina P, 1994.Marshall, P. David. Celebrity and Power. Minneapolis: University of Minnesota Press, 2001.Marshall, P. David. “Intimately Intertwined in the Most Public Way: Celebrity and Journalism.” The Celebrity Culture Reader. Ed. P. David Marshall. Oxon: Routledge, 2006. 316-323.Marshall, P. David. “New Media – New Self: The Changing Power of Celebrity.” The Celebrity Culture Reader. Ed. P. David. Marshall. Oxon: Routledge, 2006. 634-644.Marshall, P. David. “Personifying Agency: The Public–Persona–Place–Issue Continuum.” Celebrity Studies 4.3 (2013): 369-371.Marshall, P. David. “Persona Studies: Mapping the Proliferation of the Public Self.” Journalism 15.2 (2014): 153-170.Newsnight. BBC 2. 20 Sep. 2010. 22.30-23.00.Peace One Day. Dir. Jeremy Gilley. Peace One Day, 2004.Peace One Day Concert: Live at the Royal Albert Hall Gilley. Dir. Jeremy Gilley. Peace One Day, 2008.Peace One Day Part Three. Dir. Jeremy Gilley. Peace One Day, 2010.Robèrt, Karl-Henrik. The Natural Step: Seeding a Quiet Revolution. Gabriola Island, British Columbia: New Society Publishers, 2002.Thomas, Mark. Belching Out the Devil: Global Adventure with Coca-Cola. London: Ebury Press, 2008.United Nations General Assembly. “International Day of Peace. A/RES/55/282" 111th Plenary Meeting. 2001. 10 June 2014 ‹http://www.un.org/en/ga/search/view_doc.asp?symbol=A/RES/55/282&Lang=E›.Unleash Your Power of Influence. Triumphant Events and Peace One Day. 2010.