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Dissertations / Theses on the topic 'Collagen Type 1 CTGF'

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1

Zhou, Zhenqing. "BIOLOGICAL SIGNIFICANCE OF HEPARIN-BINDING GROWTH FACTORS HB-EGF AND CTGF." Miami University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=miami1258498601.

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2

Mackay, Katrina. "Molecular analysis of type 1 collagen genes in inherited disorders." Thesis, University of Leicester, 1992. http://hdl.handle.net/2381/34442.

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The collagens are a family of related proteins which contain at least one triple-helical domain, a structure which is determined by the unique amino acid sequence of the polypeptide subunits. These proteins each have a specific function in the extracellullar matrices of connective tissues of multicellular organisms. In humans, type I collagen, the most abundant collagen type, is the major structural component of skin, tendon and bone. Mutations in the two genes encoding the subunits of type I collagen, COL1A1 and COL1A2, result in heterogeneous phenotypes. Some mutations result in osteogenesis
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3

Tang, Ming. "Atomic-scale biophysics modelling of type I collagen in the extracellular matrix." Thesis, Queensland University of Technology, 2019. https://eprints.qut.edu.au/124650/1/Ming_Tang_Thesis.pdf.

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This thesis explores the biophysics of collagen in the extracellular matrix under external stimuli, by performing cutting edge MD simulations. The obtained results provide significant insights into the design and manufacturing of artificial biomaterials for surgical tissue treatments, of collagen for regenerative medicine applications, and of gold nanoparticles for biomedical applications. The probed biophysical properties consist of the structural properties and the mechanical properties, where the mechanical properties of collagen are regulated by its structure at different levels of hierarc
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4

Dzobo, Kevin. "Matrix-mediated regulation of type 1 collagen synthesis and degradation in cultured fibroblasts." Doctoral thesis, University of Cape Town, 2009. http://hdl.handle.net/11427/3125.

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Includes abstract.<br>Includes bibliographical references (leaves 122-157).<br>Stromal cells and the extracellular matrix (ECM) components provide the microenvironment that is pivotal for cell growth, motility, attachment and differentiation. Fibroblasts are some of the cells responsible for the synthesis of most of the extracellular matrix proteins. Type I collagen is the most abundant extracellular matrix protein in the human body and is found in tissues requiring high tensile strength. In this study we investigated the effect of a pre-formed fibroblast-derived extracellular matrix on the ex
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5

Soininen, Raija. "Structure of the gene for the [alpha] 1 chain of human type IV collagen." Oulu, Finland : University of Oulu, 1989. http://catalog.hathitrust.org/api/volumes/oclc/20482376.html.

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6

Seehra, Kamaljit Jyoti Kaur. "An investigation into mechanisms inhibiting human microvascular endothelial cell (HMEC-1) capillary cord formation on collagen type 1." Thesis, University of Nottingham, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.438638.

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7

Стужук, Анастасія Юріївна. "Способи отримання та перспективи застосування колагену типу 1". Магістерська робота, Київський національний університет технологій та дизайну, 2021. https://er.knutd.edu.ua/handle/123456789/19255.

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Дипломна магістерська робота присвячена вивченню способів отримання та перспектив застосування колагену типу 1 у різних галузях промисловості. У роботі наведено критичний огляд літературних джерел, присвячених застосуванню та отриманню колагену, обґрунтовано технологічну схему отримання сухого препарату колагену з відходів шкіряного виробництва за допомогою Bacillus subtilis, яка передбачає, в тому числі, стадії отримання посівного матеріалу, вирощування культури та культивування, поділ отриманого гідролізату на фракції та фільтрацію. Обґрунтовано вибір технологічного обладнання для реалізації
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8

Miles, Benjamin Nicholas. "On the use of collagen type-I in the growth of hydroxyapatite on micro-fabricated biomimetic dentin." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/58203.

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Dentin hypersensitivity is a condition that affects 4 – 14% of western populations like the U.K. It is characterised by a short sharp pain in the gums, usually experienced when an individual consumes cold food or drink. Typical treatments that are primarily delivered by sensitive toothpastes initially relied upon disruption of neuronal activity with potassium ions. However, more recently the most advanced over the counter treatments now act to occlude the tubules present in dentin that are involved in the hydrodynamic cause of dentinal pain. Pre-clinically, the efficacy of these occlusive trea
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9

Afifi, Amal. "A molecular investigation into type 1 collagen genes in Osteogenesis imperfecta and an evaluation of targeted gene repair." Thesis, University of Sheffield, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422178.

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10

Ndlovu, Matladi N. "The role of DNA methylation in transcriptional regulation of the human type 1 alpha 2 collagen (COL1A2) gene." Master's thesis, University of Cape Town, 2002. http://hdl.handle.net/11427/3144.

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Bibliography leaves 70-97.<br>Type I collagen is the most abundant collagen molecule in vertebrate connective tissue and it consists of a heterotrimer of two alpha 1 (COL1A1) and one alpha 2 (COL1A2) chains. Reduced collagen gene expression is almost always correlated with pathological conditions and cellular transformation. Numerous studies have suggested that methylation of the cytosines in CpG dinucleotides is inversely correlated with transcriptional activity and plays a critical role in differential gene expression.
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11

Wei, Yi. "Type XII Collagen, Fibroblast Growth Factor-1, and Fibroblast Growth Factor-4 in Newt Limb and Tail Regeneration /." The Ohio State University, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487935125882142.

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12

Salomonsson, Maya. "Exploring innate type B cells in an animal model for autoimmune arthritis." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-229792.

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B cells have a central role in the pathogenesis of collagen-induced arthritis (CIA), an animal model of the autoimmune disease rheumatoid arthritis. In this report, a specific subset of an innate type of B cells, B-1 B cells, have been studied for the involvement in CIA. The B-1 B cells were shown to produce small amounts of collagen-specific antibodies upon stimulation in vitro, suggesting that they play a minor role in the development of CIA. This report also includes how marginal zone B cells, another innate type of B cells with natural collagen-reactivity, can be identified in the medullar
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13

Grant, Struan F. A. "Studies on genetic susceptibility to osteoporosis : analysis of cis-acting sequences in the collagen type I alpha 1 gene." Thesis, University of Aberdeen, 1995. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU543267.

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In osteogenesis imperfecta, an osteoporotic phenotype results from mutations in the protein coding regions of the collagen type I genes - COLIA1 and COLIA2. Genetic factors are known to play an important role in determining bone mass. For this reason, it was considered that more subtle mutations in the transcriptional control regions of the collagen type I genes might be associated with osteoporosis. The polymerase chain reaction was used, followed by single-stranded conformation polymorphism detection (PCR/SSCP) to screen for polymorphisms in the transcriptional control regions (the promoter
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14

Pillusky, Fernanda Maia. "INFLUÊNCIA DO FOTOSSENSIBILIZADOR AZUL DE METILENO DISSOLVIDO EM ETANOL NA TERAPIA FOTODINÂMICA ANTIMICROBIANA SOBRE O STATUS OXIDATIVO SISTÊMICO E COLÁGENO GENGIVAL EM MODELO EXPERIMENTAL DE PERIODONTITE." Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/6173.

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The purpose of this study was to evaluate the effects of an antimicrobial photodynamic therapy (aPDT) employing the photosensitizer methylene blue dissolved in ethanol on the systemic oxidative status likewise on the gingival collagen content of rats with periodontitis. Male Wistar rats were randomly divided into two main groups: NC (negative control; no periodontitis) and the remaining animals were submitted to periodontitis induction group. In the last group, the cotton ligature was placed at the first right mandibular molar of each animal in a submarginal position to induce experimental per
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Welander, Maria. "Soft tissue integration to dental implants /." Göteborg : Deptartment of Periodontology, Institute of Odontology, The Sahlgrenska Academy at University of Gothenburg, 2008. http://hdl.handle.net/2077/18196.

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16

Young, Gregory Scott. "The application of thermal microscopy, differential scanning calorimetry, and fourier transform infrared microspectroscopy to characterize deterioration and physiochemical change in fibrous Type 1 collagen." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420072.

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17

Rahal, Andrés. "Improved specificity of MRI diagnosis of collagenous lesions in tendon : a dissertation /." San Antonio : UTHSC, 2007. http://proquest.umi.com/pqdweb?did=1397911041&sid=1&Fmt=2&clientId=70986&RQT=309&VName=PQD.

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18

LOCATELLI, LUIGI. "Expression of aVB6 integrin by Pkhd1-defective cholangiocytes links enhanced ductal secretion of Macrophage chemokines to progressive portal fibrosis in Congenital Hepatic Fibrosis." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2013. http://hdl.handle.net/10281/41733.

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BACKGROUND AND AIMS: Congenital Hepatic Fibrosis (CHF) is caused by mutations in PKHD1, a gene encoding for fibrocystin, a protein of unknown function, expressed in cholangiocyte cilia and centromers. In CHF, biliary dysgenesis is accompanied by severe progressive portal fibrosis and portal hypertension. The mechanisms responsible for portal fibrosis in CHF are unclear. The αvβ6 integrin mediates local activation of TGFβ1 and is expressed by reactive cholangiocytes during cholestasis. To understand the mechanisms of fibrosis in CHF we studied the expression of αvβ6 integrin and its regulation
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19

Fell, Cody Alexander. "Soft robotic devices for emulating vascular mechanobiology." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/213109/1/Cody%20Alexander_Fell_Thesis.pdf.

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This thesis comprises two research projects undertaken as part of the dual biofabrication master's program between Queensland University of Technology and Utrecht University. The two projects focused on leveraging biofabrication, tissue-culture, and soft robotics to develop novel methods for fabricating 3D vascular and colon tissue, respectively. The first project developed a novel approach for conditioning cells using soft robotics that emulate vascular biomechanics, whereas the second project combined bioink micromoulding and melt electrospinning writing to fabricate 3D colon organoid constr
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20

Hyry, M. (Marjo). "Lysyl hydroxylases 1 and 2:characterization of their in vivo roles in mouse and the molecular level consequences of the lysyl hydroxylase 2 mutations found in Bruck syndrome." Doctoral thesis, Oulun yliopisto, 2012. http://urn.fi/urn:isbn:9789514298424.

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Abstract The extracellular matrix is not just a scaffold for cells and tissues, but rather a dynamic part of the human body. Characteristics of collagens, the major protein components of the extracellular matrix, are determined already during synthesis and mutations in genes encoding collagens, unbalance of regulators or dysfunction of collagen modifying enzymes, for instance, can lead to severe clinical complications. Certain hydroxylysine residues formed by lysyl hydroxylases (LHs) function in collagens as precursors of collagen cross-links that stabilize collagenous structures and thereby t
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21

Yang, Yueh-Hsun. "Development of hydrodynamically engineered cartilage in response to insulin-like growth factor-1 and transforming growth factor-beta1: formation and role of a type I collagen-based fibrous capsule." Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/49072.

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Articular cartilage which covers the surfaces of synovial joints is designed to allow smooth contact between long bones and to absorb shock induced during joint movement. Tissue engineering, a means of combining cells, biomaterials, bioreactors and bioactive agents to produce functional tissue replacements suitable for implantation, represents a potential long-term strategy for cartilage repair. The interplay between environmental factors, however, gives rise to complex culture conditions that influence the development of tissue-engineered constructs. A fibrous capsule that is composed of abun
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22

Le, Cao cuong. "Rôle de LRP-1 dans la prolifération des cellules issues de cancer du côlon en matrice tridimensionnelle de collagène de type I." Thesis, Reims, 2020. http://www.theses.fr/2020REIMS026.

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Le récepteur low-density lipoprotein receptor-related protein-1 (LRP-1) est un récepteur d’endocytose multifonctionnel impliqué dans de nombreux processus physiologiques et pathologiques. Plusieurs études ont montré que LRP-1 joue un rôle crucial lors des processus de tumorigenèse et durant la progression tumorale, notamment en régulant l’expression de protéines membranaires. Des études antérieures ont montré l'implication des récepteurs du collagène de type I de la famille des Discoidin Domain Receptors (DDRs) dans la régulation de la prolifération des cellules cancéreuses en 3D. Le but de ce
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23

Guignel, Nadine Joëlle. "Skeletal Status and Bone Turnover in Overweight Young Men with and without Sleep Apnea Syndrome." Thesis, Virginia Tech, 2005. http://hdl.handle.net/10919/33725.

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Obesity is a worldwide epidemic increasing at an alarming rate among youth who are facing similar health problems as adults. Sleep Apnea Syndrome (SAS) is an underdiagnosed comorbidity of obesity, characterized by repetitive nocturnal interruptions in breathing. Obesity is associated with delayed skeletal maturation in overweight youth, but mechanisms contributing to this problem are unclear. Obesity and SAS both have been shown to disrupt regulatory hormones and cytokines that influence bone accretion during adolescence. PURPOSE: The purpose of this study was to assess the combined effects o
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Matsui, Yuto. "Visualization of procollagen IV reveals ER-to-Golgi transport by ERGIC-independent carriers." Kyoto University, 2020. http://hdl.handle.net/2433/259728.

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POLITO, UMBERTO. "THE MENISCUS: BASIC SCIENCE TO IMPROVE KNOWLEDGE FOR TISSUE ENGINEERING." Doctoral thesis, Università degli Studi di Milano, 2020. http://hdl.handle.net/2434/707236.

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This thesis was thought with the intent to try to fill some lacunae in the knowledge of the anatomic-dependent features of the meniscus. In particular, the study of the effects of endogenous and exogenous factors upon the development of this structure will be outlined. Endogenous factors have been considered those factors that cannot be attributed to external or experimental factors: the effect of age and growth has been investigated focusing on the variation of the, matrix components (collagen types, GAGs and decorin), cellular phenotypic modifications and meniscal morpho-functional structure
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Kanno, Cláudia Misue. "Efeitos da ciclosporina, fenitoína e nifedipina sobre a síntese e degradação de colágeno da gengiva de macacos-prego (Cebus apella) : estudo histoquímico e através de RT-PCR /." Araçatuba : [s.n.], 2006. http://hdl.handle.net/11449/102345.

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Orientador: Alvimar Lima de Castro<br>Banca: Renata Tucci<br>Banca: José Fernando Garcia<br>Banca: Sérgio Roberto Peres Line<br>Banca: José Américo de Oliveira<br>Resumo: INTRODUÇÃO: As alterações em gengiva induzidas por medicamentos têm sido pouco estudadas quanto à expressão in vivo dos genes das metoloproteinases (MMPs). O objetivo do presente trabalho foi avaliar o padrão histológico de distribuição de fibras colágenas após a administração de ciclosporina, nifedipina ou fenitoína e correlacionar com a expressão dos genes do colágeno do tipo I, MMP-1 e MMP2. MATERIAL E MÉTODO: Amostras da
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Rizzato, Vanessa Rodrigues. "Envolvimento da neuraminidase-1 na atrofia muscular." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5138/tde-01122014-094857/.

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Sialidose é uma doença neurossomática causada pela deficiência congênita da neuraminidase-1 (Neu1), enzima envolvida na regulação do catabolismo de sialoglicoconjugados nos lisossomos. Com o acúmulo de sialoglicoconjugados, ocorre comprometimento sistêmico e neurológico. Achados histológicos musculares incluem expansão da matriz extracelular (MEC) devido à proliferação anormal de fibroblastos, invasão das fibras musculares por componentes da MEC, fragmentação do citoplasma, formação vacuolar e atrofia das fibras musculares. Entretanto o mecanismo da atrofia muscular na deficiência de Neu1 não
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Kanno, Cláudia Misue [UNESP]. "Efeitos da ciclosporina, fenitoína e nifedipina sobre a síntese e degradação de colágeno da gengiva de macacos-prego (Cebus apella): estudo histoquímico e através de RT-PCR." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/102345.

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Made available in DSpace on 2014-06-11T19:32:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-03-27Bitstream added on 2014-06-13T20:22:59Z : No. of bitstreams: 1 kanno_cm_dr_araca.pdf: 1730975 bytes, checksum: 620b9c72f44529033f574688f3ea9bde (MD5)<br>INTRODUÇÃO: As alterações em gengiva induzidas por medicamentos têm sido pouco estudadas quanto à expressão in vivo dos genes das metoloproteinases (MMPs). O objetivo do presente trabalho foi avaliar o padrão histológico de distribuição de fibras colágenas após a administração de ciclosporina, nifedipina ou fenitoína e correlacionar co
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Ivanoff, Jyrki. "Migration on extracellular matrix surface and infiltration into matrix - two distinguishable activities of human T cells." Doctoral thesis, Umeå University, Clinical Microbiology, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-159.

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<p>Migration of T-lymphocytes on a surface coated with extracellular matrix (ECM) components (two-dimensional (2-D) migration) and migration (infiltration) into a matrix (Three-dimesional (3-D) migration) are complex events and the underlying mechanisms are not yet fully understood. Here 2-D and 3-D migration were studied by use of seven leukemic T-cell lines representing discrete differentiation stages, a non-leukemic T-cell clone, and normal peripheral blood T cells. peripheral blood lymphocytes and the T-cell clone produced nanogram quantities of various chemokines, as compared to a product
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Gonçalves, Fernanda Magalhães. "Efeitos do LDL oxidado em macrófagos M2. Implicações na aterosclerose." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5146/tde-29112017-101149/.

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A aterosclerose é uma doença crônica onde duas características marcantes são observadas: retenção de lipídios e inflamação. Compreender as interações entre as células do sistema imunológico e as lipoproteínas envolvidas na aterogênese são desafios urgentes, uma vez que as doenças cardiovasculares são a principal causa de morte no mundo. Os macrófagos são cruciais para o desenvolvimento de placas ateroscleróticas e para a perpetuação da inflamação em tais lesões; estas células também estão diretamente envolvidas na ruptura de placa instável. Recentemente diferentes populações de macrófagos estã
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Urzel, Vanessa. "Apport de la résonance magnétique nucléaire des solides à la caractérisation chimique et à la datation des os en anthropologie médico-légale." Thesis, Bordeaux, 2014. http://www.theses.fr/2014BORD0019/document.

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L’estimation du délai post mortem est une étape fondamentale en anthropologie médico-légale. À ce jour, peu de méthodes précises et fiables existent. Les objectifs de notre travail étaient d’étudier le tissu osseux et son évolution dans les années et siècles suivant le décès en développant la Résonance Magnétique Nucléaire (RMN) des solides du carbone13C et du proton1H. Nous avons analysé une centaine d’os humains et animaux pour lesquels nous connaissions l’âge au décès, le sexe, la date de décès et les conditions de conservation. Nous avons caractérisé les os au niveau moléculaire en identif
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Ferreira, Yuri Afonso. "Análise da expressão das metaloproteinases e seus inibidores teciduais no músculo detrusor de pacientes com obstrução infravesical por hiperplasia prostática benigna." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5153/tde-13012015-111245/.

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Introdução: A obstrução infravesical (OIV) de longo prazo secundária a hiperplasia prostática benigna (HPB) pode causar alterações funcionais e morfológicas na bexiga. Um dos principais eventos consiste no aumento da deposição de colágeno e perda de complacência vesical, levando a alteração de armazenamento e esvaziamento urinário. O aumento da deposição de colágeno na matriz extracelular (MEC) da musculatura detrusora é a principal razão para a diminuição da complacência vesical. Na bexiga, assim como em outros órgãos, este fenômeno depende da atividade equilibrada de enzimas proteolíticas, i
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Lusito, E. "A Network-based Approach to Breast Cancer Systems Medicine." Doctoral thesis, Università degli Studi di Milano, 2015. http://hdl.handle.net/2434/265572.

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Breast cancer is the most commonly diagnosed cancer and the second leading cause of cancer death in women. Although recent improvements in the prevention, early detection, and treatment of breast cancer have led to a significant decrease in the mortality rate, the identification of an optimal therapeutic strategy for each patient remains a difficult task because of the heterogeneous nature of the disease. Clinical heterogeneity of breast cancer is in part explained by the vast genetic and molecular heterogeneity of this disease, which is now emerging from
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Wan-Hsuan, Tung, and 董宛璇. "The Role of Rac1/MLK3/JNK/AP-1 in CTGF-Induced Type I Collagen Expression in Lung Fibroblasts." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/53899417254003645945.

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碩士<br>臺北醫學大學<br>醫學科學研究所<br>98<br>Several evidences suggest that connective tissue growth factor (CTGF) overproduction underlies the development of lung fibrosis. Development of lung fibrosis is characterized by excessive deposition of collagens in the lung interstitium. Mixed linage kinase 3 (MLK3) can be regulated by Rac and then activate downstream molecule JNK, which in turns activates transcription factor activator protein-1(AP-1). In this study, we found that CTGF could induce collagen expression, and overexpression of wild-type MLK3 also enhanced collagen expression. Overexpressed domina
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Yang, Hui Lin, та 楊慧霖. "Mechanism of TGF-β1 on the expression of CTGF and type I collagen in hepatic stellate cells". Thesis, 2012. http://ndltd.ncl.edu.tw/handle/74315930419119430793.

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碩士<br>長庚大學<br>中醫學系天然藥物<br>101<br>Liver fibrosis is a significant health issue worldwide and continues to increase in prevalence in Taiwan. The main character of liver fibrosis is excessive production of extracellular matrixes and pro-inflammatory factors. Activated hepatic stellate cells (aHSCs) produce high concentrations of transforming growth factor-β1 (TGF-β1), connective tissue growth factor (CTGF), and type I collagen which are closely related to the pathogenesis of liver fibrosis. However, the effects and action mechanisms of TGF-β1 on CTGF and type I collagen expression remain controve
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Lee, Hyejin (Rosa). "Critical role of membrane-type 1 matrix metalloproteinase in collagen phagocytosis by fibroblasts." 2007. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=452972&T=F.

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Tang, Ja-Reng, and 湯家潤. "The Regulation of Type II Collagen Gene Expression by Interleukin-1 in Rabbit Chondrocytes." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/28148486945984848271.

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碩士<br>台北醫學院<br>醫學研究所<br>85<br>Progressive and irreversible destruction of the extracellular matrix in articular cartilage is a major feature of arthritis. When the joint is destroyed, the prothesis of artificial joint is indicated. However, the metallic joint prothesis often causes severe ankylosis and some complications such as wear problems. Therefore, a biomaterial, collagen template, manufactured in this laboratory was designed to regenerate the articular cartilage.IL-1 is thought to
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Taylor, Ian Wesley. "The relative contribution of vitamin D receptor (VDR), collagen type 1, α-1 (COL1A1), tumor necrosis factor receptor 2 (TNFR2), polymorphisms, physical activity and bone mineral-free lean mass to bone parameters in children". Thesis, 2002. http://hdl.handle.net/2429/13993.

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Background: This study sought to investigate the relationship of physical activity (PA), dietary calcium and 3 candidate gene (VDR, COL1A1 and TNFR2) genotypes on bone mass in children (n = 327, age 10.33 ± 0.65). The study also sought to investigate the effect of PA and genotype on bone mineral-free lean mass (BMFL). Finally, the relationships between bone mass and BMFL and PA, BMFL and genotype and PA and genotype interactions were investigated. Methods: Anthropometric data (height, sitting height and weight) was determined using standard techniques. Bone mass, and BMFL were assed using tota
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Bertrand, Marie-Jeanne. "Validation de modalités d’imagerie innovantes de l’athérosclérose par cathéter intravasculaire bimodal combinant fluorescence (NIRF) et ultrasons (IVUS) couplé à l’injection locale de sondes moléculaires in vivo ciblant ICAM-1 et le collagène." Thèse, 2018. http://hdl.handle.net/1866/22544.

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