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1

Kumar, Lutesh, Pooja Sharma, and Dinesh Kumar. "Colebrookea oppositifolia." Indo Global Journal of Pharmaceutical Sciences 09, no. 02 (2019): 132. http://dx.doi.org/10.35652/igjps.2019.92s30.

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2

Fan Yang, Xing-Cong Li, Han-Qing Wang, and Chong-Ren Yang. "Flavonoid glycosides from Colebrookea oppositifolia." Phytochemistry 42, no. 3 (June 1996): 867–69. http://dx.doi.org/10.1016/0031-9422(95)00975-2.

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3

Yadav, Dinesh Kumar. "Pharmacognostical, Phytochemical and Pharmacological profile of Colebrookea oppositifolia Smith." Journal of Drug Delivery and Therapeutics 9, no. 6-s (December 15, 2019): 233–37. http://dx.doi.org/10.22270/jddt.v9i6-s.3745.

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Colebrookea oppositifolia commonly known as ‘Bhaman’ is distributed throughout India from the Himalayas down to Deccan. The plant is used traditionally as such as dermatitis, dysentery, fever, headache, peptic ulcer, haemostatic, wounds, as anti-fertility agent, fungicide, and the roots of the plant has been most widely used for the treatment of epilepsy.. Medicinally, it has been proven to possess various pharmacological activities like treating corneal opacity or conjunctivitis, sore eyes due to its anti-inflammatory properties, cardioprotective, hepatoprotective, anti-inflammatory, antihelmintic, antifungal, antioxidant, antimicrobial, antinociceptive, cytotoxic activity, anticonvulsant, antiulcer, antimicrobial, anti-fertility, antipyretic and insecticide. Further, studies reveal the presence of various phytochemical constituents mainly flavone glycosides viz. chrysin, negletein, landenein; leaves contain 5,6,7- tri-methoxyflavone, 5,6,7,4'-tetramethoxyflavone, acteoside, and quercetin in the bark; root contains stearic, palmitic, oleic acids, triacontanol, flavone glycoside echioidin, 5,6,7-trimethoxyflavone and 4',5,6,7- tetra methoxy flavone; sugars and vitamins have also been isolated from this plant. These studies reveal that Colebrookea oppositifolia is a source of medicinally active compounds and have various pharmacological effects; hence, this drug encourage finding its new therapeutic uses. Keywords: Colebrookea oppositifolia, wound healing, anticonvulsant, Lamiaceae
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4

Ishtiaq, Saiqa, Mehvesh Bashir Meo, Muhammad Shaharyar Khan Afridi, Shehla Akbar, and Shahid Rasool. "Pharmacognostic studies of aerial parts of Colebrookea oppositifolia Sm." Annals of Phytomedicine : An International Journal 5, no. 2 (December 2016): 161–67. http://dx.doi.org/10.21276/ap.2016.5.2.23.

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5

Peron, Gregorio, Jan Hošek, Ganga Prasad Phuyal, Dharma Raj Kandel, Rameshwar Adhikari, and Stefano Dall’Acqua. "Comprehensive Characterization of Secondary Metabolites from Colebrookea oppositifolia (Smith) Leaves from Nepal and Assessment of Cytotoxic Effect and Anti-Nf-κB and AP-1 Activities In Vitro." International Journal of Molecular Sciences 21, no. 14 (July 11, 2020): 4897. http://dx.doi.org/10.3390/ijms21144897.

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Here we report the comprehensive characterization of the secondary metabolites from the leaves of Colebrookea oppositifolia Smith, a species used as medicinal plant in the traditional medicine of Nepal. Phytochemical screening of bioactives was performed using an integrated LC-MSn and high resolution MS (Mass Spectrometry) approach. Forty-three compounds were tentatively identified, mainly aglyconic and glycosilated flavonoids and phenolic acids, as well as other bioactives such as coumarins and terpenes were detected. Furthermore, the NF-κB and AP-1 inhibitory activity of C. oppositifolia extract were evaluated, as well as its cytotoxicity against THP-1 cells, in order to assess the potential use of this herb as a source of anti-inflammatory and cytotoxic compounds. The results so far obtained indicate that C. oppositifolia leaves extract could significantly reduce the viability of THP-1 cells (IC50 = 6.2 ± 1.2 µg/mL), as well as the activation of both NF-κB and AP-1 at the concentration of 2 μg/mL. Our results indicate that Nepalese C. oppositifolia is a valuable source of anti-inflammatory and cytotoxic compounds. The phytochemical composition reported here can partially justify the traditional uses of C. oppositifolia in Nepal, especially in the treatment of inflammatory diseases, although further research will be needed to assess the full potential of this species.
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6

Viswanatha, Gollapalle Lakshminarayanashastry, Mohan Drishya, Darisi Venkata Kishore, Hanumanthappa Shylaja, and Yogananda Moolemath. "Characterization and Anti-stroke Activity of Stem Extract of Colebrookea oppositifolia Smith." Journal of Biologically Active Products from Nature 10, no. 3 (May 3, 2020): 250–63. http://dx.doi.org/10.1080/22311866.2020.1791731.

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7

Viswanatha, Gollapalle Lakshminarayanashastry, Honnavalli Yogish Kumar, Marikunte V. Venkataranganna, Nunna Bheema Lingeswara Prasad, and Hanumanthappa Shylaja. "Anticonvulsant Activity Guided Isolation of Acteoside from Methanolic Root Extracts of Colebrookea oppositifolia Smith." Journal of Biologically Active Products from Nature 9, no. 5 (September 3, 2019): 328–34. http://dx.doi.org/10.1080/22311866.2019.1702900.

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8

Chinchansure, Ashish, Manisha Arkile, Dinesh Shinde, Dhiman Sarkar, and Swati Joshi. "A New Dinor-cis-Labdane Diterpene and Flavonoids with Antimycobacterium Activity from Colebrookea oppositifolia." Planta Medica Letters 3, no. 01 (March 14, 2016): e20-e24. http://dx.doi.org/10.1055/s-0042-102200.

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9

Viswanatha, Gollapalle Lakshminarayanashastry, Marikunte V. Venkataranganna, Nunna Bheema Lingeswara Prasad, and Shylaja Hanumanthappa. "Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats." Journal of Ethnopharmacology 223 (September 2018): 63–75. http://dx.doi.org/10.1016/j.jep.2018.05.009.

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10

Viswanatha, Gollapalle Lakshminarayanashastry, G. P. Sowmya, Hanumanthappa Shylaja, and Yogananda Moolemath. "Methanolic Stem Extract of Colebrookea oppositifolia Attenuates Epilepsy in Experimental Animal Models: Possible Role of GABA Pathways." Journal of Biologically Active Products from Nature 10, no. 1 (January 2, 2020): 44–58. http://dx.doi.org/10.1080/22311866.2020.1740109.

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11

Viswanatha, Gollapalle Lakshminarayanashastry, Hanumanthappa Shylaja, Darisi Venkata Kishore, Marikunte V. Venkataranganna, and Nunna Bheema Lingeswara Prasad. "Acteoside Isolated from Colebrookea oppositifolia Smith Attenuates Epilepsy in Mice Via Modulation of Gamma-Aminobutyric Acid Pathways." Neurotoxicity Research 38, no. 4 (August 17, 2020): 1010–23. http://dx.doi.org/10.1007/s12640-020-00267-0.

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12

Ali, Intzar, Punita Sharma, Krishan Avtar Suri, Naresh Kumar Satti, Prabhu Dutt, Farhat Afrin, and Inshad Ali Khan. "In vitro antifungal activities of amphotericin B in combination with acteoside, a phenylethanoid glycoside from Colebrookea oppositifolia." Journal of Medical Microbiology 60, no. 9 (September 1, 2011): 1326–36. http://dx.doi.org/10.1099/jmm.0.031906-0.

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13

Viswanatha, Gollapalle Lakshminarayanashastry, Marikunte V. Venkataranganna, and Nunna Bheema Lingeswara Prasad. "Ameliorative potential of Colebrookea oppositifolia methanolic root extract against experimental models of epilepsy: Possible role of GABA mediated mechanism." Biomedicine & Pharmacotherapy 90 (June 2017): 455–65. http://dx.doi.org/10.1016/j.biopha.2017.03.078.

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14

Ghimire, Ritambar, Pankaj Kumar Yadav, Arjun Kumar Shrestha, Ananta Raj Devkota, and Shovit Khanal. "Ripening Regulation of Banana Cv. Malbhog Using Different Ripening Inducers." Turkish Journal of Agriculture - Food Science and Technology 9, no. 12 (December 24, 2021): 2113–23. http://dx.doi.org/10.24925/turjaf.v9i12.2113-2123.4294.

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This experiment was carried out under the study entitled “Ripening regulation of the banana Cv. Malbhog using different ripening inducers” for controlling the ripening of the banana, for improvement of quality attributes and post-harvest life of banana. The experiment was conducted at laboratory of horticulture, Agriculture and Forestry University, Rampur, Chitwan, Nepal from 14th March to 16th April 2019. These experiments were laid out in completely randomized design in which the first experiment comprised of seven treatments consisting of distilled water spray, ethephon @ 250 ppm, ethephon @ 500 ppm, ethephon @750 ppm, ethephon@1000 ppm, Dhurseli (Colebrookea oppositifolia) leaves and Ripe banana replicated thrice. Different post-harvest parameters were recorded at the interval of two days for the experiment till any one of the treatment attained score 6 in the color chart. In this experiment, the CI-6 stage was reached earlier on the 9th day with the use of ethephon @ 1000 ppm but ethephon @ 500 ppm was found more effective regarding quality parameters with TSS (21˚B), and TSS/TA (34.66). The maximum physiological loss in weight (12.927%) and pulp peel ratio (3.65) was observed with ethephon@1000ppm and the minimum was achieved in banana sprayed with distilled water. The shelf life of banana was seen minimum (13.33 days) in ethephon @ 1000 ppm and maximum (20.33 days) in banana sprayed with distilled water.
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15

Sharma, Neha, Vidushi Khajuria, Shilpa Gupta, Chetan Kumar, Anjana Sharma, Nazir Ahmad Lone, Satya Paul, et al. "Dereplication Based Strategy for Rapid Identification and Isolation of a Novel Anti-inflammatory Flavonoid by LCMS/MS from Colebrookea oppositifolia." ACS Omega 6, no. 45 (November 2, 2021): 30241–59. http://dx.doi.org/10.1021/acsomega.1c01837.

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16

Viswanatha, Gollapalle Lakshminarayanashastry, Marikunte V. Venkataranganna, Nunna Bheema Lingeswara Prasad, and Shylaja Hanumanthappa. "Corrigendum to “Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats” [J. Ethnopharmacol. 223 15 (2018) 63–75]." Journal of Ethnopharmacology 229 (January 2019): 343. http://dx.doi.org/10.1016/j.jep.2018.07.020.

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17

Gupta, R. S., Rajesh K. Yadav, V. P. Dixit, and M. P. Dobhal. "Antifertility studies of Colebrookia oppositifolia leaf extract in male rats with special reference to testicular cell population dynamics." Fitoterapia 72, no. 3 (March 2001): 236–45. http://dx.doi.org/10.1016/s0367-326x(00)00311-7.

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18

Kumar, Dinesh, Rajeev K. Singla, Rohit Sharma, Pooja Sharma, Lutesh Kumar, Navdeep Kaur, R. K. Dhawan, Shailesh Sharma, and Kamal Dua. "Phytochemistry and Polypharmacological potential of Colebrookea oppositifolia Sm." Current Topics in Medicinal Chemistry 23 (December 2, 2022). http://dx.doi.org/10.2174/1568026623666221202112414.

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Background: Colebrookea oppositifolia Sm. is a valuable traditional therapeutic plant belonging to the family Lamiaceae. It is a dense and wool-like shrub that is mostly found in subtropical regions of some countries of Asia, such as China and India. It has been widely used for the mitigation of nervous system disorders like epilepsy. The active constituents of the plant have exhibited antioxidant, anti-microbial, and antifungal properties, which are considered due to the presence of polyphenols and flavonoids as chief chemical constituents. Flavonoids like quercetin, landenein, chrysin, and 5, 6, 7-trimethoxy flavones cause protein denaturation of the microbial cell wall. Objectives: To comprehend and assemble the fragmented pieces of evidence presented on the traditional uses, botany, phytochemistry, and pharmacology of the plant to reconnoiter its therapeutic perspective and forthcoming research opportunities. Methods: The available information on Colebrookea oppositifolia has been established by electronically searching peer-reviewed literature from PubMed, Google Scholar, Springer, Scopus, Web of Science, and Science Direct over the earlier few years. Results: The plant has been greatly used for the preparation of many herbal medicines which are used for treating traumatic injuries, fever, rheumatoid arthritis, headache, and gastric problems. From the aerial parts of the plant, a phenylethanoid glycoside named acteoside has been isolated and evaluated for its therapeutic potential viz. immunomodulatory, neuroprotective, hepatoprotective, analgesic, anti-tumour, antispasmodic, antioxidant, antibacterial, free radical scavenger, and improving sexual function. Acteoside showed neuroprotective activities against Aβ-peptide, which is neurotoxic and causes apoptosis. The petroleum ether extract of the plant leaves offers many active compounds like sitosterol, n-triacontane, hydroxydotriacontyl ferulate, acetyl alcohol, and 3,7,4,2-tetramethoxyflavones which have shown hepatoprotective potential. Conclusion: The plant should be evaluated further for the estimation of some other health benefits. The consequences of restricted pharmacological screening and reported phytomolecules of Colebrookea oppositifolia Sm. advocate that there is still an exigent requisite for in-depth pharmacological studies of the plant.
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19

Gajapathy, C. "Cytological Studies in some Indian Medicinal Plants." Nelumbo, May 17, 2024, 49–51. http://dx.doi.org/10.20324/nelumbo/v3/1961/76574.

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Meiotic chromosome numbers of 12 taxa of medicinal plants are reported. Chromosome counts for Colebrookea oppositifolia n=16, Cyathula prostrata n=21, Aerva lanata n=8, Trema orientalis n=20, Girardinia zeylanica n=10 and Streblus asper n=13 are new records for these genera. Chromosome number for Ophiorrhiza mungos n=11, Plumbago zeylanica n=14, Clerodendrum viscosum n=24, Polygonum chinense n=11, Acalypha indica n=10 and A. paniculata n=10 are reported for the first time.
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20

Sen, Yadunandan, Rekha Chouhan, Siya Ram Meena, Rekha Sapru Dhar, and Sumit G. Gandhi. "Development of micropropagation protocol for Colebrookea oppositifolia Sm. using nodal segments." Vegetos, September 1, 2023. http://dx.doi.org/10.1007/s42535-023-00697-z.

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21

"Colebrookea Oppositifolia Anti Arthritic Potential Vs Methotrexate in Pristane Induced Rat Arthritis." Proceedings of Shaikh Zayed Medical Complex Lahore 36, no. 1 (January 2, 2022). http://dx.doi.org/10.47489/pszmc-825361-26-30.

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22

Viswanatha, Gollapalle L., H. Shylaja, H. Yogish Kumar, M. V. Venkataranganna, and N. B. L. Prasad. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine, October 6, 2020. http://dx.doi.org/10.1007/s13596-020-00513-y.

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23

Ajaib, Muhammad. "Phytochemical, antibacterial and antifungal activities of leaves and bark of Colebrookea oppositifolia: an ethnomedicinal plant." Pure and Applied Biology 7, no. 1 (March 10, 2018). http://dx.doi.org/10.19045/bspab.2018.70017.

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24

Bhardwaj, Nidhi, Sunil Puri, Amita Kumari, Ankush Chauhan, and Akshay Kumar. "Investigation on antioxidant, antimicrobial, anti-inflammatory, and neuropsychiatry potential of phyto-mediated ZnONPs using Colebrookea oppositifolia." Journal of Drug Delivery Science and Technology, May 2024, 105748. http://dx.doi.org/10.1016/j.jddst.2024.105748.

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25

Anwar, Rukhsana, Muhammad Khalil, Abida Latif, and Lam Kok Wai. "Investigation of anti hypertensive activity of standardized Colebrookea oppositifolia methanolic extract and elucidation of possible mechanism of action." Frontiers in Pharmacology 9 (2018). http://dx.doi.org/10.3389/conf.fphar.2018.63.00056.

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26

Brari, J., and D. R. Thakur. "Larvicidal effects of eight essential oils against Plodia interpunctella and T. castaneum, serious pests of stored products worldwide." Journal of Entomological and Acarological Research 50, no. 1 (July 10, 2018). http://dx.doi.org/10.4081/jear.2018.7469.

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Fumigant toxicity of eight essential oils obtained by hydrodistillation from eight plant species viz. Artemisia maritima L., Cinnamomum zeylanicum Blume, Citrus hystrix DC., Colebrookea oppositifolia Sm., Pelargonium hortorum Bailey, Rabdosia rugosa Wall. ex Benth, Thuja occidentalis L. and Zanthoxylum armatum DC. were tested against different immature stages of Tribolium castaneum (Herbst) and Plodia interpunctella (Hubner) both are serious pests of stored products worldwide. 8-10 day and 18-20 day old larvae of P. interpunctella and T. castaneum were used for the bioassay. R. rugosa oil gave 80.03±5.6% mortality at 100 µl/ml followed by 72.28±4.9% at 50 µl/ml against 8-10 day old larvae. Whereas 65.47±2.9% mortality at 100 µl/ml followed by 62.09±1.8% mortality at a dose of 50 µl/ml was obtained against 18-20 day old larvae of T. castaneum after 120 hrs. At a lowest concentration of 10 µl/ml R. rugosa oil produced 53.8.33±2.2 % mortality for 8-10 day old larvae and a mortality of 40.55±3.9% respectively was obtained for 18-20 day old larvae of P. interpunctella after 120 hrs. Among eight essential oils tested R. rugosa had the highest toxicity followed by A. maritima, C. zeylanicum, Z. armatum, T. occidentalis, P. hortorum, C. oppositifolia and C. hystrix against both the insect pests. The results obtained also showed that tolerance increases as the immature stages grow older and 18-20 day old larvae were least susceptible to all the treatments as compared to 8-10 days old larvae. Larvae of T. castaneum were found to be most susceptible for all treatments than P. interpunctella.
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27

Puri, G. S., and S. D. Mahajan. "The Study of the Evergreen Vegetation of Mahabaleshwar Area." Nelumbo, May 17, 2024, 109–37. http://dx.doi.org/10.20324/nelumbo/v2/1960/76635.

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Mahabaleshwar plateau lies in the Western Ghats, 76 miles from Poona on South West. The altitude of the plateau is 4300' to 4800'. The rainfall of Mahabaleshwar is from 250" to 300". The plateau is formed of Deccan Trap and on account of high rainfall conditions, lateritic soils are found in most of the places.The vegetation of Mahabaleshwar is an evergreen forest consisting of the following species:Memecylon umbellatum Burm., Olea dioica Roxb., Syzygium cumini (L.) Skeels., Temiinalia chebula Retz., Actinodaphne angustifolia Nees., Randia brandisii Gamble.The shrub layer has the following important species:Lasiosiphon eriocephalus Decne., Zizyphus rugosa Lam., Pavetta indica L. Allophyllus cobbe Blutne, Colebrookea oppositifolia Sm.The herbaceous layer consists mainly Pteris quadriaurita Retz., Pteris aquilina L. Crotalaria retusa L. and Bryophyllum pinnatum Oken.The trees are mainly 15-20 meters high, with their trunks and branches being covered over with mosses, orchids and epiphytic ferns.Vegetation studies were made from the Lingmala fall, Arther's Seat road, Mahad road and Panchagani and the main part of the plateau.Where the tree vegetation has been destroyed a scrub forest consisting of the following species occurs:Pleris quadriaurita Retz., Pleris aquilina L. Crotalaria relusa L. Solarium giganteum Jacq., Pavella indica L. Ageratum conyzoides L. Asplenium falcatum Lam.This vegetation is a biotic controlled serai community and the evergreen forest is the climax.
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28

Viswanatha, Gollapalle Lakshminarayanashastry, Hanumanthappa Shylaja, Krishnadas Nandakumar, Subbanna Rajesh, and CH K. V. L. S. N. Anjana Male. "Acteoside isolated from Colebrookea oppositifolia attenuates I/R brain injury in Wistar rats via modulation of HIF-1α, NF-κB, and VEGF pathways." Inflammopharmacology, August 7, 2021. http://dx.doi.org/10.1007/s10787-021-00851-6.

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