Academic literature on the topic 'Coffee Extract'
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Journal articles on the topic "Coffee Extract"
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Dianastri, Rr Nektara Titan, Pudji Astuti, and Rendra Chriestedy Prasetya. "Daya Hambat Ekstrak Biji Kopi Robusta (Coffea Canephora) terhadap Bakteri Porphyromonas gingivalis (in vitro)." STOMATOGNATIC - Jurnal Kedokteran Gigi 18, no. 2 (October 11, 2021): 69. http://dx.doi.org/10.19184/stoma.v18i2.28060.
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Periodontitis is mostly caused by plaque and Pophyromonas gingivalis bacteria as the main cause. The outer membrane layer of the Porphyromonas gingivalis wall produces pathogenic virulence factors, such as lipopolysaccharides which will activate inflammatory cells and cause phagocytosis of antigens thereby triggering free radicals. Robusta coffee beans naturally contain caffeine, phenolic compounds, trigonellin, and chlorogenic acids as antibacterial and anti-inflammatory. The purpose of this study was to determine the inhibition of Robusta (Coffea canephora) coffee bean extract 0.5%; 0.75%; 1%; 1.25%; 1.5% and 3% on the growth of Porphyromonas gingivalis in vitro and to find out the lowest concentration of Robusta (Coffea canephora) coffee bean extract which has inhibitory effect on the growth of Porphyromonas gingivalis. In this study were divided into 8 treatment groups namely positive control, negative control, 0.5% robusta coffee bean extract, 0.75%, 1%, 1.25%, 1.5% and 3%. Petridish dishes containing TSA media that have been sterilized, added P. gingivalis suspension with density according to Mc standard. Farland Then a sterile white test blank with a diameter of 6 mm that is still sterile is placed on top of the bacterial growth media in accordance with the placement of the treatment group and dropped with all 8 treatment materials. After 24 hours incubated in a desiccator, the inhibition of robusta coffee bean extracts against the growth of Porphyromonas gingivalis bacteria was observed and data collection was done by measuring the inhibition zone using calipers. The results obtained robusta coffee bean extract at concentrations of 3%, 1.5%, 1.25% and 1%, have an antibacterial power which is suspected because Robusta coffee beans naturally contain ingredients such as caffeine, polyphenols and chlorogenic acids which have antibacterial activity while the robusta coffee bean extract with a concentration of 0.5% and 0.75% does not have antibacterial power against Pophyromonas gingivalis. Robusta coffee bean extract with a concentration of 1% is the smallest concentration of Robusta (Coffea canephora) coffee bean extract which can inhibit the growth of Porphyromonas gingivalis.
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Rosa, Yunilda, and Riyanto Riyanto. "Potential of Robusta Coffee Bean Extract (Coffea canephora) Peaberry Roasted and Green Bean Pagar Alam City against the Growth of Candida albicans Fungus." Jurnal Biologi Tropis 22, no. 4 (November 16, 2022): 1108–14. http://dx.doi.org/10.29303/jbt.v22i4.4311.
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A type of coffee plant that is widely cultivated in the city of Pagar Alam, South Sumatra is Robusta coffee (Coffea canephora). The robusta coffee plant is one of the traditional plants that can be used as a medicine. The purpose of this research is to analyze the potential of Robusta peaberry Sangrai coffee bean extract and green bean from Pagar Alam city against the growth of Candida albicans fungus. The test method is carried out by extraction, phytochemical screening test and anti-fungal activity test of Robusta coffee bean extract. The results of testing antifungal activity showed that ethanol extracts of roasted peaberry robusta coffee beans and green bean can inhibit the growth of C. albicans fungi by forming clear zones. Secondary metabolite compounds contained in roasted peaberry robusta coffee bean extract and green bean are alkaloids, flavonoids, tannins, saponins and terpenoids. The minimum inhibitory content (MIC) of ethanol extract of roasted peaberry robusta coffee beans and green bean against the growth of C. albicans fungus in vitro is at a concentration of 10%. Based on the results of research on ethanol extract, roasted peaberry robusta coffee beans and green bean have the potential to be anti-fungal because they can inhibit the growth of C. albicans fungus.
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Wijaya, Willy, Rini Devijanti Ridwan, and Hendrik Setia Budi. "Antibacterial ability of arabica (Coffea arabica) and robusta (Coffea canephora) coffee extract on Lactobacillus acidophilus." Dental Journal (Majalah Kedokteran Gigi) 49, no. 2 (February 14, 2017): 99. http://dx.doi.org/10.20473/j.djmkg.v49.i2.p99-103.
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Background: Dental caries is the most commonly dental health problem found in Indonesia. Lactobacillus acidophilus (L. acidophilus) is bacteria playing a role in the development and continuation of caries. Some researches in Dentistry Faculty show that many plants are efficacious for oral health. One of them is coffee bean. Coffee bean containing caffeine, phenolic, trigonelline, and chlorogenic acid is reported to have antimicrobial activity. Purpose: This research aimed to determine the differences in the inhibition of Arabica and Robusta coffee extract to L. acidophilus. Method: This research was an laboratory experimental research. The method used was well diffusion method using seven samples for each treatment group. BHI-A and inoculated L.acidophilus bacteria was poured into each petri dish, and then 8 pitted holes were made with a diameter of 5mm and a depth of 3mm using a ring. Next, Arabica or Robusta coffee extracts at a concentration of 100%, 75%, 50%, 12.5%, 6.25%, and 3.125% were put into each of the pitted hole until it was full, and a negative control was also prepared. They then were put in an incubator at a temperature of 37 °C for 24 hours. Afterwards, measurements and observations were conducted on inhibition zone area. Result: Robusta coffee extract at the concentrations of 100% and 75% had greater inhibitory than Arabica coffee extract (p<0.05). Meanwhile, Arabica and Robusta coffee extracts at the concentrations of 50% and 25% had no significant inhibitory difference (p>0.05). Conclusion: In conclusion, Robusta and Arabica coffee extracts have inhibitory effects on L.acidophilus. Robusta coffee bean extract, nevertheless, has better inhibitory effects than Arabica coffee bean extract.
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Barguil, Beatriz M., Mário Lúcio V. Resende, Renata S. Resende, J. Evando A. Beserra Júnior, and Sônia M. L. Salgado. "Effect of extracts from citric biomass, rusted coffee leaves and coffee berry husks on Phoma costarricencis of coffee plants." Fitopatologia Brasileira 30, no. 5 (October 2005): 535–37. http://dx.doi.org/10.1590/s0100-41582005000500014.
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Phoma leaf spot, caused by Phoma costarricensis poses a serious threat to coffee (Coffea arabica) production, especially in the highlands of the state of Minas Gerais, Brazil. Extracts of citric biomass, coffee berry husks and coffee leaves severely affected by rust caused by Hemileia vastatrix, were evaluated against P. costarricensis. In an in vitro assay, aqueous extracts of rusted leaves and berry husks plus the commercial extracts based on citric biomass named Ecolife® and Agromil® were tested at various dilutions on the mycelial growth inhibition of P. costarricensis. In vivo, coffee seedlings maintained in glasshouse, were sprayed with these extracts seven days before inoculation of P. costarricensis. Only extracts from citric biomass had inhibitory effects on the fungus. In vivo, Ecolife® (5 ml/l), Agromil® (5 g/l) and the aqueous extract of rusted coffee leaves (dilution 1:6) reduced Phoma leaf spot. Both, Ecolife® and the extract of rusted coffee leaves were significantly more effective in reducing the area under the lesion progress curve when applied at lower doses, indicating a possible effect on the induction of resistance.
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Wenas, Desy Muliana, Lisana Sidqi Aliya, and Nita Usikatul Janah. "AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN KOPI ARABIKA (Coffea arabica L.) PADA EDEMA TIKUS." Buletin Penelitian Tanaman Rempah dan Obat 31, no. 2 (December 21, 2020): 75. http://dx.doi.org/10.21082/bullittro.v31n2.2020.75-84.
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<em>The coffee leaf contains flavonoid compounds that are known as an antiinflammation agent. The study aimed to determine antiinflammatory activity of arabica coffee's leaf extract (</em>Coffea arabica<em> L.) against edema on white rat soles of carrageenan-induced rats. The research began with the maceration extraction of coffee leaf in 70% ethanol. The inflammation test was held by measuring the formation of edema using a plethysmometer. The dosages of arabica coffee leaf extract used were 60 mg.kg<sup>-1</sup>, 120 mg.kg<sup>-1</sup>, and 180 mg.kg<sup>-1</sup> rat weight of white Sprague Dawley rat (</em>Rattus norvegicus<em>). The data were analyzed by Kruskal Wallis and Mann Whitney non-parametric tests. Phytochemical screening showed that arabica coffee leaf extract contained flavonoid, saponin, alkaloid, tannin and triterpenoids compound. The arabica coffee leaf extract showed the best antiinflammatory activity at the dose of 180 mg.kg<sup>-1</sup> rat weight with 71.66% inhibition percentage at the 5<sup>th</sup> hour, which was better than the positive control (66.91% edema inhibition at the same hour). This result determined that the leaf extract of arabica coffee had antiinflammatory activity. However, it is necessary to study the acute and chronic toxicity and formulates the arabica coffee leaf extract as a pharmacy product.</em>
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Fatmawati, Sofia, Landyyun Rahmawan Sjahid, Nadiyya Maulida Utami, and Kartini Kartini. "Total Phenolic, Total Flavonoid Content and in vitro Sun Protection Factor test of Arabica Coffee Leaves Extract (Coffea arabica L)." Journal of Science and Technology Research for Pharmacy 1, no. 2 (January 22, 2022): 16–25. http://dx.doi.org/10.15294/jstrp.v1i2.51374.
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Background: Arabica coffee leaf (Coffea arabica L.) is a well-known plant by the Indonesian people because it has many benefits apart from being a drink. Coffee leaves are known to have good antioxidant activity. The use of antioxidants in sunscreen preparations can prevent various diseases caused by UV radiation from UV rays’ sunlight.
Aim: This study aims to determine the phenol content, the flavonoid content and the value of Sun Protection Factor (SPF) from differences between solvent extracts of arabica coffee leaves (Coffea arabica L.).
Method: The extraction method used was maceration with solvents: 70% ethanol, 96% ethanol and methanol. Determination of phenol content was carried out using the Folin ciocalteu method. Determination of flavonoid content was done by the AlCl3 method. SPF value is based on the Mansur equation from absorbance scanning using UV Spectrophotometry.
Result: The results obtained were the highest phenol and flavonoid content is in the methanolic extract of arabica coffee namely 62.371 ± 0.47 mgGAE/g and 8.6707 ± 0.04 mgQE/g. In the SPF test, the highest value was obtained from 70% ethanol extract of 5.0593 ± 1.28 at 100 ppm extract concentration with intermediate protection category.
Conclusion: Arabica coffee leaves have the potential as an active ingredient in herbal sunscreens
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Rashad, Asmaa E. E. M., Mohsen K. Abdel Latif, and Manar A. Abdul-Aziz. "Assessment of Anti-Cancerous Effect of Green, Roasted and Decaffeinated Coffee on Oral Squamous Cell Carcinoma Cell Line (In Vitro Study)." Journal of Natural Remedies 21, no. 3 (July 6, 2021): 235. http://dx.doi.org/10.18311/jnr/2021/26862.
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Oral Squamous Cell Carcinoma (OSCC) is one of the most prevailing malignancies of the head and neck area. So far, treatment methods are associated with harmful effects which drive attention towards natural compounds such as coffee. The current study attempted to test the anti-cancerous effect of green coffee, medium roasted coffee and decaffeinated coffee in OSCC cell lines and correlate the obtained results with their total phenolic content. We prepared coffee extracts using soxhlet apparatus. Then, we purchased and sub-cultured OSCC-25 cell into four study groups. We subjected three of those groups to coffee extracts separately. We left the remaining group without any treatment as a control group. We assessed cell cytotoxic effect of each extract by MTT viability assay. Additionally, we evaluated the apoptotic effect of each extract on OSCC-25 cell lines using flowcytometric analysis. Finally, we measured the total phenolic content in each coffee extract. The results revealed that coffee extracts induced varying degrees of cell cytotoxicity and apoptosis. Green coffee showed the highest cytotoxic and apoptotic effect followed by medium roasted coffee, then decaffeinated coffee. The total percentage of necrotic cells were higher in the coffee extracts groups, compared to the control group with a higher value in favor of green coffee followed by medium roasted coffee. Upon chemical analysis, the results showed that green coffee extract contained the highest concentration of phenolic compounds followed by medium roasted coffee then decaffeinated coffee extracts. We concluded that green coffee was the most potent anti-cancer extract. It seems plausible that coffee, and particularly green coffee could be for treating of OSCC.
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Handayani, Retty. "Formulasi Sediaan Lipbalm dari Ekstrak Biji Kopi Arabika (Coffea Arabica L.) Java Preanger Sebagai Emolien." Jurnal Ilmiah Farmasi Farmasyifa 4, no. 1 (January 30, 2021): 105–11. http://dx.doi.org/10.29313/jiff.v4i1.6497.
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Lipbalm preparations are a decorative cosmetic dosage form for moisturizing lips. One of the most important components of lipbalm preparations is an emollient. Emollients work by covering the damaged skin with beads of fat so that the skin of the lips becomes softer and moisturized. Arabica coffee beans (Coffea arabica L.) java preanger contain linoleic acid which functions as an emollient. This study aims to make a lipbalm formulation containing extracts of Arabica coffee beans (Coffea Arabica L). Lipbalm preparations made with variations in the concentration of coffee extract 3%, 6% and 9%. The resulting formula is then evaluated for its physical stability. The irritation test is carried out using the patch test method, testing the effectiveness of emollients using a skin analyzer. The results showed that variations in the extract of coffee used (3%, 6% and 9%) showed that the concentration of 9% was more stable. The irritation test results show that all three formulas are safe to use. Based on the results of the effectiveness test shows that the formula with a concentration of 9% gives a good emollient effect after use based on statistical tests the paired samples T-test method.Keywords : emollients, coffee bean extracts, formulation, lipbalm.
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Araújo, Alexandre Santos, Leandro do Santos Leal, Lorena Araújo Peixoto Correia, Jennifer da Silva Andrade, Artur Magno Fiais Barreto, Carina Cristina de Oliveira Santos Costa, Amanda Amorim Silva Cardoso, et al. "Commercial extract of coffee (Coffea arabica L.) and mango essence as potential attractants for Ceratitis capitata (Wiedemann) (Diptera: Tephritidae)." EntomoBrasilis 15 (December 10, 2022): e1008. http://dx.doi.org/10.12741/ebrasilis.v15.e1008.
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Various host compounds have been investigated to produce an alternative attractant for monitoring and controlling pest insects. Several studies evidenced that volatile molecules released by coffee and mangoes attracted both male and female Ceratitis capitata (Wiedemann), a significant pest in fruit crops. In this study, we tested the effectiveness of the commercial glycolic extract of coffee (Coffea arabica L.) and a commercial mango essence (Mangifera indica L.) to attract C. capitata. We identified the main volatile compounds (VOCs) emitted from such products. The experiments were conducted in field cages and showed that the glycolic extract of coffee attracts both sexes of C. capitata, while the mango essence attracts only males. After seven days, the pH of the coffee extract and mango essence did not change. These results indicate that attractants based on commercial fruit extracts and essences can be an option for integrated pest management of the Mediterranean fruit fly in orchards.
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Sakaki, Junichi, Melissa Melough, Cathy Yang, Anthony Provatas, Christopher Perkins, and Ock Chun. "Determination of the Estrogenic Activity of Coffee Extract Solutions Prepared from Capsule Coffee Using the BG1Luc4E2 Assay." Current Developments in Nutrition 4, Supplement_2 (May 29, 2020): 464. http://dx.doi.org/10.1093/cdn/nzaa045_097.
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Abstract Objectives Estrogenic chemicals (ECs) possess estrogenic activity (EA) which can have harmful effects on the reproductive system. Coffee is known to have estrogenic potency due to its natural phytoestrogens, but coffee prepared from plastic capsules (capsule coffee) may increase exposure to ECs and consequently increase EA, potentially increasing risk to reproductive health. The objective of this study was to determine the EA of capsule coffee extract solutions in vitro. Methods Six varieties of capsule coffee and two varieties of coffee prepared from whole beans using a stainless-steel French press were first brewed then concentrated and extracted. The BG1Luc4E2 assay was then conducted to determine the EA of the coffee extracts. The normalized EA (% RME2) of the coffee extracts was determined as the relative estrogenic potency compared to the maximum normalized EA of the positive control 17β-estradiol (set to 100 % RME2). EA was determined if at least one data point on the concentration-response curve was above 15% RME2 and confirmed via inhibition with the estrogen receptor antagonist ICI 182,780. The correlation between the EA estimated by the BG1Luc4E2 assay and the estrogenic potential (EEQ) was determined with Spearman's rank correlation coefficient. Results All eight coffee extract solutions tested positive for EA and results were confirmed by their complete inhibition with ICI. The level of EA for the six capsule coffee extracts ranged from 48 to 56 % RME2, while the level of EA for the two coffee varieties prepared from whole beans were 40 and 42 % RME2. There was a significant correlation between EA and EEQ was (ρ = 0.8857, P = 0.0333). Conclusions These results indicate that the EAs of capsule coffees were higher than that of coffee prepared from a plastic-free method and that the EA measured in an in vitro model was correlated with the calculated estrogenic potential of the coffee extract's EC contents. Future studies are warranted in in vivo models as well as in humans as tests of estrogenic potency in vitro do not necessarily predict the effects in living organisms. Funding Sources This study was supported by the National Institutes of Health.
Dissertations / Theses on the topic "Coffee Extract"
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Garde, William K. "Application of Moringa Oleifera Seed Extract to Treat Coffee Fermentation Wastewater." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1471347356.
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Peron, Gregorio. "Metabolomics in natural products research: application to in vivo bioactivity studies involving nutraceuticals." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3426678.
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The analysis of urinary metabolite changes can provide information on the effects of food supplements or health-promoting products on healthy subjects or animal models. Specimen collection is non-invasive, long-term experiments can be easily conducted and urinary biomarkers of oxidative stress can also be measured, offering the opportunity to study the effects of a nutritional intervention and evaluate the redox status of the considered organism. In this thesis, three natural extracts were selected, namely Polygonum cuspidatum Sieb. et Zucc. (rich in resveratrol), Vaccinium macrocarpon Aiton (cranberry, rich in type A procyanidins) and green Coffea canephora Pierre ex Froehn. beans (GCBE, rich in chlorogenic acids), on the basis of their distribution on the market and on the basis of the information regarding their in vivo activity actually available in literature. In the first part of the work, the effects of P. cuspidatum dry extract were studied in healthy adult rats during a 49-days supplementation, using a combined 1H NMR and UPLC-HRMS metabolomics approach. Because of the reported antioxidant activity of resveratrol, the urinary amounts of two oxidative stress biomarkers were measured by targeted HPLC–MS/MS analyses and, due to the supposed “anti-aging” effects of resveratrol, multivariate models were designed in order to compare the aging effects between control and treated animals. Specific biomarkers were then selected and identified, and their amounts in urine were monitored throughout the experimental period.
UPLC-MS metabolomics approaches were used to evaluate the mode of action of cranberry against uropathogenic Escherichia coli in two independent experiments, using an animal model and enrolling healthy adult volunteers, respectively. The experimental design was similar for the two trials, and the aim was to observe if the results obtained from the first animal experiment were reproducible in humans, being cranberry supplements claimed for treatment of UTIs in human consumers. In the first experiment, healthy Sprague−Dawley rats were orally supplemented with a standardized cranberry extract for 35 days, to mimic a prolonged consumption of cranberry by healthy subjects. 24-h urinary outputs were collected weekly during the experiment, and samples were subjected to UPLC−MS analysis using an untargeted approach. In a second experiment on the same animal model, a single dose of cranberry was administered to animals and the changes of urinary composition at 2, 4, 8, and 24 h after extract administration were monitored. Anti-adhesive properties of all the urine samples were studied. Furthermore, the markers related to cranberry intake were discovered using a multivariate data analysis approach. Finally, a specific chromatographic method was developed for the measurement of unmodified PAC-A in urine. In the experiment involving human volunteers, these consumed an oral sachet containing 360 mg of dry cranberry extract and 100 mg of quercetin. Urine samples were collected at 2, 4, 6, 8 ad 24 hours after product administration and the anti-adhesive properties of urine samples were tested using an in vitro assay on E. coli. In order to correlate possible observed bioactivity with modification of urinary composition, LC-MS-based targeted and untargeted metabolomics approaches were used.
Finally, a clinical trial on a small number of healthy adult volunteers was performed to study the effects of a prolonged (30 days) supplementation with 400 mg of green coffee bean extract. The 24-h urinary samples were collected weekly, and analyzed by LC-MS. Multivariate data analysis approaches were applied and also targeted analysis were performed to measure urinary oxidative stress biomarkers, namely allantoin and 8-hydroxydeoxyguanosine (8-OHdG), in order to assess the potential antioxidant activity of GCBE in vivo.L’analisi del metaboloma urinario e delle sue variazioni può fornire utili informazioni sull’effetto del consumo di prodotti nutraceutici da parte di volontari sani o in modelli animali. I vantaggi di usare l’urina come matrice di studio sono correlati alla scarsa invasività di campionamento, al semplice trattamento pre-analitico dei campioni, alla possibilità di progettare e condurre esperimenti a lungo termine ed alla possibilità di quantificare alcuni markers di stress ossidativo. Sulla base della loro attuale diffusione sul mercato e dei dati di bioattività disponibili in letteratura, per il lavoro di tesi qui presentato sono stati presi in esame tre prodotti nutraceutici, contenenti rispettivamente estratti secchi di Polygonum cuspidatum Sieb. et Zucc. (contenente resveratrolo), Vaccinium macrocarpon Aiton (cranberry, contenente proantocianidine di tipo A) e semi verdi di Coffea canephora Pierre ex Froehn. (GCBE, contenente derivati dell’acido clorogenico). Nella prima parte di lavoro sono stati studiati gli effetti del consumo di un estratto secco di Polygonum cuspidatum per 49 giorni in ratti adulti sani, impiegando un approccio metabolomico combinato NMR/UPLC-MS. Per studiare l’effetto “anti-aging” attribuito al resveratrolo, sono stati sviluppati dei modelli multivariati in cui sono stati posti a confronto il gruppo “trattato” ed il gruppo di controllo; da questi sono stati selezionati ed identificati specifici biomarkers di invecchiamento, i quali livelli urinari sono stati poi monitorati per tutto il corso dell’esperimento. Un simile approccio UPLC-MS è stato in seguito impiegato per studiare l’attività ex vivo di un estratto secco di cranberry contro un ceppo di Escherichia coli uropatogenico. In questo caso sono stati disegnati due esperimenti indipendenti, in cui gli effetti del trattamento sono stati studiati rispettivamente in ratti sani ed in volontari umani. Nel primo esperimento è stato somministrato un estratto secco di cranberry standardizzato in procianidine per 35 giorni a ratti Sprague-Dawley, per mimare un consumo prolungato di cranberry da parte di pazienti umani. Settimanalmente è stata effettuata la raccolta delle urine delle 24 ore, ed i campioni raccolti sono stati analizzati mediante un approccio untargeted UPLC-MS. Impiegando lo stesso modello animale, è stata effettuata una singola somministrazione di cranberry e la variazione della composizione urinaria è stata studiata a 2, 4, 8 e 24 ore dopo il trattamento. Gli stessi campioni sono stati utilizzati per testarne le proprietà antiadesive contro Escherichia coli e per determinare i markers urinari correlati all’assunzione di cranberry, grazie all’impiego di tecniche statistiche multivariate ed allo sviluppo di specifici metodi cromatografici atti alla determinazione di PAC-A intatte in matrice urinaria. Nel secondo esperimento, ai volontari umani sani è stato chiesto di consumare un integratore contenente 360 mg di estratto secco di cranberry e 100 mg di quercetina. I campioni urinari sono stati raccolti a 2, 4, 6, 8 e 24 ore a seguito del trattamento e le loro proprietà antiadesive sono state testate contro un ceppo di E. coli uropatogenico. In modo da correlare l’attività biologica osservata in vitro con la modifica composizionale indotta dal trattamento, sono stai impiegati degli approcci LC-MS targeted e untargeted. Infine, è stato condotto uno studio clinico su un piccolo numero di volontari sani per studiare gli effetti di una integrazione con 400 mg di GCBE per 30 giorni. I campioni urinari delle 24 ore sono stati raccolti settimanalmente ed in seguito analizzati mediante LC-MS ed analisi statistica multivariata. Sono state eseguite analisi targeted per quantificare biomarkers urinari di stress ossidativo, al fine di valutare la potenziale attività antiossidante di GCBE in vivo.
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ARTUSA, VALENTINA. "Modulation of the Innate Immune Response by Targeting Toll-like Receptor 4 Signalling: Exploring the Role of Natural Products." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2022. http://hdl.handle.net/10281/375443.
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Per secoli, i prodotti naturali e i loro derivati hanno fornito una ricca fonte di composti per lo sviluppo di nuovi immunomodulatori. Gli immunomodulatori naturali possono fornire la chiave per controllare e, infine, sconfiggere i disturbi che colpiscono il sistema immunitario, stimolando o inibendo la risposta immunitaria con pochi effetti collaterali negativi. Molti di questi composti sono attualmente in fase di sperimentazione clinica, in particolare come agenti antiossidanti, antimicrobici e antitumorali. Tuttavia, la funzione e il meccanismo di azione dei prodotti naturali, e il modo in cui interagiscono con il sistema immunitario, devono ancora essere ampiamente esplorati.
Negli ultimi anni, la conoscenza del ruolo dei macrofagi nel contesto dell'infiammazione ha aperto numerose nuove strade, tra cui la possibilità di intervento terapeutico mirato sfruttando la plasticità intrinseca dei macrofagi per il trattamento di patologie infiammatorie acute e croniche. I recettori Toll-simili (TLR), incluso TLR4, svolgono un ruolo cruciale nelle malattie a base infiammatoria; pertanto, la via di segnalazione di TLR4 è stata identificata come bersaglio terapeutico per l'intervento farmacologico.
Questo lavoro mira a valutare il potenziale dei fitoestratti e delle sostanze fitochimiche di influenzare la via di segnalazione di TLR4 in un modello cellulare di macrofago. Nello specifico, sono stati testati estratti ottenuti da chicchi di caffè verde (GCE) e tostato (RCE), nonché acido clorogenico puro (5-CQA). Inoltre, è stato valutato l'effetto antinfiammatorio della palmitoiletanolamide (PEA) e del suo analogo sintetico RePEA.
Come modello in vitro sono stati impiegati macrofagi originati da monociti umani, derivanti dalla differenziazione di una linea cellulare (THP-1) e/o da monociti umani primari. Il saggio MTT è stato utilizzato per determinare gli effetti citotossici dei trattamenti. L'attivazione di TLR4 è stata stimolata mediante esposizione delle cellule all'endotossina batterica LPS (E. coli) in presenza o assenza di trattamento. Sono stati valutati diversi parametri: produzione di citochine pro-infiammatorie, ma anche attivazione e traslocazione nucleare dei mediatori di segnalazione intracellulare. Questi parametri sono stati misurati applicando differenti tecniche di biologia cellulare e molecolare, principalmente test di immunoassorbimento enzimatico (ELISA), immunofluorescenza e immunofissazione (Western blot). Inoltre, abbiamo impiegato diverse cellule transfettate stabilmente disponibili in commercio come strumenti per studiare il meccanismo d'azione del nostro estratto o della nostra molecola, rispettivamente le cellule THP1-XBlue™, RAW-Blue™ e HEK-Blue™.
I risultati chiave includono un marcato effetto inibitorio, dose-dipendente, degli estratti di caffè verde e tostato verso il rilascio di interferone-β (IFN-β) dopo la stimolazione con LPS. Coerentemente, l'acido clorogenico, un importante componente polifenolico degli estratti di caffè, ha mostrato un'attività biologica comparabile. Complessivamente, i risultati ottenuti forniscono nuove prove sugli effetti immunomodulatori e sul meccanismo d'azione degli estratti di caffè e dell'acido clorogenico, in particolare come modulatori della via di segnalazione pro-infiammatoria mediata da TLR4. Inoltre, la capacità della PEA di ridurre il rilascio di TNF-α da parte delle cellule microgliali stimolate con LPS è stata corroborata anche nel nostro modello di macrofagi, confermando il suo potenziale antinfiammatorio. Inoltre, RePEA, un analogo sintetico della PEA progettato per essere degradato più lentamente, si è rivelato più attivo del suo composto originario.
Questi risultati aiutano a convalidare le suddette molecole naturali, 5-CQA e PEA, ma anche RePEA, come potenziali nuovi candidati per ulteriori indagini precliniche per il trattamento delle malattie autoimmuni e infiammatorie.For centuries, natural products and their derivatives have provided a rich source of compounds for the development of new immunomodulators in the treatment of human diseases. Natural immune modulators may provide the key to control and ultimately defeat disorders affecting the immune system, by either up- or down-regulating the immune response with few adverse side effects. Many of these compounds are currently undergoing clinical trials, particularly as anti-oxidative, anti-microbial, and anti-cancer agents. However, the functions and mechanisms of action of natural products, and how they interact with the immune system, has yet to be extensively explored. In recent years, the increasing body of knowledge regarding the role of macrophages in the steady-state and in the context of inflammation has opened diverse new avenues of investigation and possibilities for therapeutic intervention targeting the inherent plasticity of macrophages for the treatment of acute and chronic inflammatory disease. Toll-Like Receptors (TLRs), including TLR4, play a crucial role in inflammatory-based diseases, therefore TLR4 signalling has been identified as a therapeutic target for pharmacological intervention. This work aims to screen and investigate the potential of phytoextracts and phytochemicals to affect TLR4 signalling in a macrophage-like cell model. Specifically, extracts from green (GCE) and roasted (RCE) coffee beans as well as pure chlorogenic acid (5-CQA) were tested. Also, the anti-inflammatory effect of palmitoylethanolamide (PEA), and its synthetic analogue RePEA, was assessed. Human monocyte-derived macrophages, deriving from the differentiation of a monocytic cell line (THP-1) and/or from human primary CD14+ monocytes, were employed as an in vitro model. MTT was used to determine cytotoxic effects of the treatments. TLR4 activation was stimulated by exposure of cells to bacterial endotoxin LPS (E. coli), in presence or absence of treatments. Different readouts were evaluated: endpoint pro-inflammatory cytokines production, as well as phosphorylation and nuclear translocation of intracellular signalling mediators. These parameters were measured applying different cellular and molecular techniques, mainly enzyme-linked immunosorbent assay (ELISA), High Content Analysis (immunofluorescence microscopy), and Western blot. Alongside, we employed different commercially available stable transfected cells as tools to investigate the mechanism of action of our tested extract or molecule, THP1-XBlue™, RAW-Blue™ and HEK-Blue™ cells, respectively. Key findings include a dramatic, dose-dependent, inhibitory effect of both green and roasted coffee extracts towards interferon-β (IFN-β) release, upon LPS stimulation. Consistently, chlorogenic acid, a major polyphenolic component of coffee extracts, showed a comparable biological activity. Additionally, novel evidence towards the immunomodulatory effects and mechanism of action of coffee extracts and chlorogenic acid as modulators of TLR4-related pro-inflammatory signalling have been provided. Alongside, PEA capability of reducing TNF-α release from LPS-stimulated microglial cells, was corroborated in our macrophage model also, confirming its anti-inflammatory potential. Moreover, RePEA, a synthetic PEA analogue designed to be degraded slower, was revealed to be more active than its parent compound. These experimental data demonstrate that natural products may act as lead molecules for the development of safe and effective immunomodulators. Taken together, these findings help to validate the above-mentioned natural molecules, 5-CQA and PEA, but also RePEA, as potential novel candidates for further preclinical investigations for the treatment of inflammatory-based disorders.
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Pardo-Benito, J. Mauricio. "Modelling studies on freeze-drying of coffee extracts." Thesis, University of Reading, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394175.
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Káčeríková, Martina. "Vývoj organických UV filtrů na bázi přírodních extraktů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2020. http://www.nusl.cz/ntk/nusl-414167.
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This diploma thesis is focused on the development of organic UV filters. Organic UV filters were extracted from natural resources and encapsulated into nanomaterial-like delivery systems such as liposomes and nanofibres. SPF of particular extracts and carriers with encapsulated extracts were measured. All of the prepared extracts as well as carriers were characterised for their content of natural substances like phenolic compounds and their antioxidant acitvity, stability, cytotoxicity, micriobial acitivity and their safety were studied too. All of the prepared materials were evaluated as suitable for use in comestic industry. However, in a future, it would be appropriate to add to the study other experimental methods to increase the active substances and at the same time increase the SPF protection factor.
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Moreno, Moreno Fabián Leonardo. "Freeze concentration of cofee extract : study of block and fallling-film techniques = Crioconcentración de extracto acuoso de café : estudio de las técnicas de bloque total y película descendente." Doctoral thesis, Universitat Politècnica de Catalunya, 2014. http://hdl.handle.net/10803/284709.
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Coffee is the most traded food in the world. The coffee industry has a great economic and social relevance worldwide. The sensory and functional properties of the product are highly important for the consumers, and therefore, technologies that promote quality preservation are highly valued in coffee processing. In the production of freezedried coffee, freeze concentration is used to remove water from the extract. Water removal in freeze concentration is achieved by cooling the solution until ice crystals form and separate. Freeze concentration is a technology known for its ability to
preserve the quality of the product thanks to low processing temperatures.
Three techniques are used according to ice crystal growth: suspension, film (progressive or falling-film) and block (total or partial). Suspension freeze concentration is the most implemented technique at the industrial level. This is an efficient technique in terms of ice purity and increased concentration; however, it requires complex systems for ice separation and many moving parts, which increases the initial and operating costs. For this reason, other freeze concentration techniques have been studied. Different techniques, such as falling-film freeze concentration, and block
freeze concentration are being developed seeking to reduce operational costs.
In the present work, block and falling-film freeze concentration techniques used to concentrate aqueous coffee extract were studied. Equipment to study those techniques was designed and implemented. The effect of the operational variables of block and falling-film freeze concentration on separation efficiency was established. Preservation of bioactive compounds, volatile compounds, antioxidant activity, and sensory quality of the coffee extract when using freeze concentration was demonstrated. Finally, an operational strategy was proposed to integrate the studied techniques. Separation efficiency obtained with this process was comparable to industrial standards.
The project was developed as a doctoral thesis under joint supervision by the Ph.D. in Biosciences of the University of La Sabana in Bogotá, Colombia and the Agribusiness Technology and Biotechnology Doctorate of the Technical University of Catalonia in Barcelona, Spain. Five papers were published as a result of the present workEl café es el alimento más comercializado en el mundo y por esto es alta su importancia económica y social. En la industria del café, la calidad sensorial y funcional de la bebida es un parámetro de alta importancia, por lo cual se promueve el uso de tecnologías de proceso que permitan su preservación. En el proceso de obtención de café soluble liofilizado se utiliza la crioconcentración como una etapa para la eliminación parcial del agua del extracto. La crioconcentración es una tecnología para la eliminación de agua de soluciones mediante su enfriamiento hasta la formación y separación de cristales de hielo. Es una técnica que puede preservar la calidad del producto debido a las bajas temperaturas que maneja. Existen tres técnicas de crioconcentración: suspensión, película y bloque. La única técnica disponible comercialmente a nivel mundial es la crioconcentración en suspensión. Esta es una técnica que logra altas eficiencias de separación pero los equipos requieren gran número de partes móviles por lo cual es relativamente costosa. Debido a esto se busca el desarrollo de técnicas más simples que a la vez consigan una alta eficiencia en la separación. La crioconcentración en película descendente y en bloque son nuevas técnicas que se han propuesto como alternativas más simples que pueden reducir costos operacionales. En el presente proyecto se estudió la crioconcentración en bloque total y en película descendente para la obtención de extractos concentrados de café. Se realizó el diseñó de una unidad de estudios para la crioconentración. Igualmente, se estableció el efecto de las variables operativas de la crioconcentración en bloque y en película sobre la eficiencia de la separación y se demostró la preservación de los componentes bioactivos, la preservación de los componentes volátiles y de la calidad sensorial del extracto de café. Se obtuvieron modelos matemáticos para la predicción del coeficiente de distribución en el hielo que permite predecir el comportamiento de la crioconcentración. Finalmente, se propuso una estrategia operativa para integración de las técnicas estudiadas que permite obtener eficiencias de separación acordes con los estándares industriales. El proyecto se desarrolló bajo la modalidad de Cotutela de Tesis Doctoral en forma conjunta entre el Doctorado en Biociencias de la Universidad de La Sabana en Bogotá, Colombia y el Doctorado en Tecnología Agroalimentaria y Biotecnología de la Universidad Politécnica de Cataluña en Barcelona, España. Como resultado del proyecto se publicaron cinco artículos en revistas indexadas.
El cafè és l'aliment més comercialitzat del món i té una gran importància econòmica i social. En la indústria del cafè, la qualitat sensorial i funcional de la beguda és un paràmetre important la qual cosa incentiva l'ús de tecnologies de procés que permetin mantenir-ne la qualitat. Durant el procés d'obtenció de cafè liofilitzat s'utilitza la crioconcentració com etapa prèvia d'eliminació de part de l'aigua continguda en la solució. La crioconcentració és una tecnologia que permet l'eliminació d'aigua d'una solució a través del seu refredament fins a la formació i la separació dels cristalls de gel. Es tracta d'una tècnica que pot preservar la qualitat del producte a causa de les baixes temperatures utilitzades. Hi ha tres tècniques de crioconcentració: suspensió, pel·lícula i bloc. La única tècnica disponible comercialment arreu del món és la crioconcentració en suspensió. Aquesta és una tècnica que aconsegueix una gran eficiència en la separació, però és relativament cara per la qual cosa es busca el desenvolupament de tècniques més senzilles que al mateix temps aconsegueixin una alta eficiència de separació. La crioconcentració de pel·lícula descendent i en bloc es mostren com a alternatives. En aquest projecte hem estudiat la crioconcentració en bloc total i en pel·lícula descendent per a la producció d'extractes concentrats de cafè. S'ha dissenyat una unitat d'estudi per a la crioconcentracio. També s'ha establert l'efecte de les variables operatives de la crioconcentració en bloc i pel·lícula sobre l'eficàcia de la separació i s'ha demostrat la preservació de compostos bioactius, la preservació dels components volàtils i de la qualitat sensorial de l'extracte de cafè. S’han obtingut models matemàtics per a la predicció del coeficient de distribució en el gel que li permeten predir el comportament de la crioconcentració. Finalment, es proposa una estratègia operativa per a la integració de les tècniques estudiades permetent obtenir eficiències de separació coherents amb estàndards de la indústria. El projecte s’ha desenvolupat en forma de tesi cotutelada conjuntament entre el doctorat en Biociències de la Universidad de La Sabana de Bogotà, Colòmbia i el doctorat en Tecnologia dels aliments i Biotecnologia de la Universitat Politècnica de Catalunya a Barcelona, Espanya. Arran del projecte hi ha cinc articles publicats en revistes indexades.
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Delgado, Paula Aparecida. "Desenvolvimento de processo enzimatico para redução de sedimentos em extratos de cafe soluvel." [s.n.], 2008. http://repositorio.unicamp.br/jspui/handle/REPOSIP/266230.
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Orientador: Telma Teixeira FrancoTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Quimica
Made available in DSpace on 2018-08-10T23:17:08Z (GMT). No. of bitstreams: 1 Delgado_PaulaAparecida_D.pdf: 2150542 bytes, checksum: 6d1fcc0446226d64e7f55a55da813d57 (MD5) Previous issue date: 2008
Resumo: Polissacarídeos são os principais constituintes do café verde, torrado e solúvel, sendo principalmente galactomananos e arabinogalactanos. Um aspecto importante em relação a estes polissacarídeos é a insolubilidade, umas das possíveis razões para a formação de sedimentos na produção de café solúvel, reduzindo o rendimento do processo. Em face disto, o objetivo deste trabalho foi investigar a redução de sedimentos em extrato de café pela ação de enzimas. Diversas preparações comerciais de pectinases foram selecionadas e suas diferentes atividades determinadas. Rohapect B1L apresentou a maior atividade de mananase. Adicionalmente, a maioria das preparações estudadas apresentou outras atividades enzimáticas, tais como mananase, endoglucanase, xilanase, além da atividade atestada pelos fabricantes. Frações solúveis e insolúveis do extrato de café e sedimento foram preparadas e suas composições determinadas. Os principais componentes do extrato de café e sua fração insolúvel foram carboidratos e proteínas, enquanto que a fração insolúvel do sedimento apresentou também uma fração significativa de lignina. Pela análise dos carboidratos, galactose, arabinose e manose foram os principais monossacarídeos obtidos após hidrólise ácida, confirmando a presença de galactomananos e arabinogalactanos. Galactomanano com baixo grau de ramificação foi o principal polissacarídeo encontrado nas frações insolúveis. Biopectinase CCM, Rohapect B1L, Pectinase 444L e Galactomananase ACH foram as preparações enzimáticas mais eficientes na redução de sedimento do extrato de café, sendo Rohapect B1L e Galactomananase ACH as mais viáveis, cujas concentrações ótimas foram 0,3 e 0,1 mgproteína/gsubstrato, respectivamente. A massa molecular média dos components do extrato de café foi 18 kDa, a qual decresceu 6,6% após hidrólise com Rohapect B1L. O principal açúcar liberado por esta enzima foi a manose, sugerindo sua ação sobre as cadeias de mananos do café, devido a alta atividade de mananase. Os extratos hidrolisados pelas preparações enzimáticas Rohapect B1L e Galactomananase ACH foram avaliados sensorialmente. Provadores treinados verificaram uma pequena a moderada diferença entre os extratos hidrolisados e o controle; entretanto, o tratamento enzimático não alterou a aceitação das amostras por parte dos consumidores. Os resultados mostraram boas perspectivas para a utilização de enzimas no processo de redução de sedimentos em extratos de café solúvel
Abstract: Polysaccharides are the main components of green, roasted and soluble coffee, and they are mainly galactomannans and arabinogalactans. An important aspect about these polysaccharides is the insolubility, possibly one of the reasons for the sediments formation in the production of instant coffee, reducing the yield of the process. Thus, the aim of this work was to investigate the reduction of sediments in coffee extract by the action of enzymes. Several commercial preparations of pectinases were selected and their different activities were determined. Rohapect B1L presented the highest mannanase activity. Most of the commercial pectinases assayed presented other enzyme activities, like mannanase, endoglucanase, xylanase, besides the activity stated by the manufacturers. Soluble and insoluble fractions from coffee extract and sediment were prepared and their chemical composition determined. The main components of extract and its insoluble fraction were carbohydrates and proteins, while the insoluble fraction of sediment presented also a significant amount of lignin. Based on the carbohydrate analysis, galactose, arabinose and mannose were the main monosaccharides obtained after acid hydrolysis, confirming the presence of galactomannans and arabinogalactans. Galactomannan with low degree of branching was found to be the main polysaccharide of the insoluble fractions. Biopectinase CCM, Rohapect B1L, Pectinase 444L and Galactomannanase ACH were found to be themost effective enzyme preparations on the sediment reduction of coffee extract, being Rohapect B1L and Galactomannanase ACH the more viable ones, which optimumconcentrations were 0.3 and 0.1 mgprotein/gsubstrate, respectively. The average molecular weight of the coffee extract components was 18 kDa, which decreased 6.6% after hydrolysis with Rohapect B1L. The main sugar released by this enzyme preparation was mannose, suggesting its action on coffee mannans, due to the high activity of mannanase. The extracts hydrolyzed by Rohapect B1L and Galactomannanase ACH were evaluated for the sensory quality. Trained panelists indicated a small to moderate difference between the hydrolyzed extracts and the control; however, the enzymatic treatment did not alter the consumers¿ acceptance of the coffee extract. The results showed good perspectives for the use of enzymes in reducing sediments in coffee extracts
Doutorado
Desenvolvimento de Processos Químicos
Doutor em Engenharia Química
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Nguyen, Dang Minh Chanh, and Woo Jin Jung. "Nematicidal properties of crude extracts obtained from medicinal plants against rootlesion nematode Pratylenchus coffeae." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-190790.
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To investigate nematicidal activity against the root-lesion nematode, Pratylenchus coffeae, the methanolic extracts were obtained from 5 medicinal plants in Vietnam. Methanol extracts of the 5 samples were screened for nematicidal activity against Pratylenchus coffeae in vitro. Of the plant extracts tested, a 5 mg/ml concentration of Terminalia nigrovenulosa extract showed the highest level (95.0%) of nematicidal activity against Pratylenchus coffeae at 9 h after treatment. The remainder of the plant extracts was followed by Cinnamomum camphora (66.7%), Jasminum suptriplinerve (30.8%), Premna integrifolia (6.7%), and Treptocaulon juventas (5.8%). A 2.0 mg/ml concentration of T. nigrovenulosa resulted in 13.3, 42.5, 62.5 and 86.7% at 1, 3, 5 and 7 h after treatment, respectively against Pratylenchus coffeae. Concentration of 0.1, 0.5, 1.0 and 2.0 mg/ml of T. nigrovenulosa resulted in 26.7, 71.7, 78.3 and 86.7% effectiveness respectively, at 7 h after treatment. Also, at 3 days after exposure to T. nigrovenulosa, hatch was inhibited by 60.0, 45.8, 17.5 and 5.8% at 0.1, 0.5, 1.0 and 2.0 mg/ml, respectively. Hatch was inhibited by 65.0, 50.8, 21.7 and 6.7% at 0.1, 0.5, 1.0 and 2.0 mg/ml respectvely, at 6 days after exposure to T. nigrovenulosa. The mortality rate and hatch inhibition increased with increasing incubation time for crude extract of T. nigrovenulosaTrong nghiên cứu này, 5 cây thuốc (Cinnamomum camphora, Jasminum suptriplinerve, Premna integrifolia, Terminalia nigrovenulosa, Treptocaulon juventas) đã được sử dụng làm nguyên liệu chiết xuất bằng methanol để thử hoạt tính kháng tuyến trùng Pratylenchus coffeae. Kết quả cho thấy chiết xuất từ cây Terminalia nigrovenulosa biểu hiện hoạt tính kháng tuyến trùng cao nhất (95,0%) sau 9 giờ xử lý với nồng độ 5 mg/ml. Hoạt tính kháng tuyến trùng của các chất chiết xuất được biểu hiện theo thứ tự giảm dần lần lượt là C. camphora (66,7%), J. suptriplinerve (30,8%), P. integrifolia (6,7%) và T. juventas (5,8%). Với nồng độ 2 mg/ml của chất chiết xuất từ T. nigrovenulossa biểu hiện hoạt tính gây chết tuyến trùng Pratylenchuss coffeae là 13,3; 42,5; 62,5 và 86,7% sau 1, 3, 5 và 7 giờ xử lý theo thứ tự. Ở cùng thời điểm sau xử lý 7 giờ, các nồng độ 0,1; 0,5; 1,0 và 2,0 mg/ml chiết xuất của T. nigrovenulossa có hoạt tính gây chết tuyến trùng Pratylenchus coffeae lần lượt là 26,7; 71,7; 78,3 và 86,7%. Bên cạnh đó, chất chiết xuất của T. nigrovenulossa cũng cho thấy tỷ lệ ức chế trứng nở cao. Cụ thể là sau 3 ngày xử lý với chất chiết xuất của T. nigrovenulossa, tỷ lệ ức chế trứng không nở là 60,0; 45,8; 17,5 và 5,8% at 0,1; 0,5; 1,0 và 2,0 mg/ml theo thứ tự. Sau 6 ngày xử lý với chất chiết xuất của T. nigrovenulossa, tỷ lệ ức chế trứng nở là 65,0; 50,8; 21,7 và 6,7% tại nồng độ 0,1; 0,5; 1,0 và 2,0 mg/ml theo thứ tự. Tỷ lệ gây chết và tỷ lệ ức chế của chất chiết xuất phụ thuộc vào cả thời gian và nồng độ xử lý
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Nguyen, Dang Minh Chanh, and Woo Jin Jung. "Nematicidal properties of crude extracts obtained from medicinal plants against rootlesion nematode Pratylenchus coffeae: Research article." Technische Universität Dresden, 2014. https://tud.qucosa.de/id/qucosa%3A29108.
Full textAbstract:
To investigate nematicidal activity against the root-lesion nematode, Pratylenchus coffeae, the methanolic extracts were obtained from 5 medicinal plants in Vietnam. Methanol extracts of the 5 samples were screened for nematicidal activity against Pratylenchus coffeae in vitro. Of the plant extracts tested, a 5 mg/ml concentration of Terminalia nigrovenulosa extract showed the highest level (95.0%) of nematicidal activity against Pratylenchus coffeae at 9 h after treatment. The remainder of the plant extracts was followed by Cinnamomum camphora (66.7%), Jasminum suptriplinerve (30.8%), Premna integrifolia (6.7%), and Treptocaulon juventas (5.8%). A 2.0 mg/ml concentration of T. nigrovenulosa resulted in 13.3, 42.5, 62.5 and 86.7% at 1, 3, 5 and 7 h after treatment, respectively against Pratylenchus coffeae. Concentration of 0.1, 0.5, 1.0 and 2.0 mg/ml of T. nigrovenulosa resulted in 26.7, 71.7, 78.3 and 86.7% effectiveness respectively, at 7 h after treatment. Also, at 3 days after exposure to T. nigrovenulosa, hatch was inhibited by 60.0, 45.8, 17.5 and 5.8% at 0.1, 0.5, 1.0 and 2.0 mg/ml, respectively. Hatch was inhibited by 65.0, 50.8, 21.7 and 6.7% at 0.1, 0.5, 1.0 and 2.0 mg/ml respectvely, at 6 days after exposure to T. nigrovenulosa. The mortality rate and hatch inhibition increased with increasing incubation time for crude extract of T. nigrovenulosa.Trong nghiên cứu này, 5 cây thuốc (Cinnamomum camphora, Jasminum suptriplinerve, Premna integrifolia, Terminalia nigrovenulosa, Treptocaulon juventas) đã được sử dụng làm nguyên liệu chiết xuất bằng methanol để thử hoạt tính kháng tuyến trùng Pratylenchus coffeae. Kết quả cho thấy chiết xuất từ cây Terminalia nigrovenulosa biểu hiện hoạt tính kháng tuyến trùng cao nhất (95,0%) sau 9 giờ xử lý với nồng độ 5 mg/ml. Hoạt tính kháng tuyến trùng của các chất chiết xuất được biểu hiện theo thứ tự giảm dần lần lượt là C. camphora (66,7%), J. suptriplinerve (30,8%), P. integrifolia (6,7%) và T. juventas (5,8%). Với nồng độ 2 mg/ml của chất chiết xuất từ T. nigrovenulossa biểu hiện hoạt tính gây chết tuyến trùng Pratylenchuss coffeae là 13,3; 42,5; 62,5 và 86,7% sau 1, 3, 5 và 7 giờ xử lý theo thứ tự. Ở cùng thời điểm sau xử lý 7 giờ, các nồng độ 0,1; 0,5; 1,0 và 2,0 mg/ml chiết xuất của T. nigrovenulossa có hoạt tính gây chết tuyến trùng Pratylenchus coffeae lần lượt là 26,7; 71,7; 78,3 và 86,7%. Bên cạnh đó, chất chiết xuất của T. nigrovenulossa cũng cho thấy tỷ lệ ức chế trứng nở cao. Cụ thể là sau 3 ngày xử lý với chất chiết xuất của T. nigrovenulossa, tỷ lệ ức chế trứng không nở là 60,0; 45,8; 17,5 và 5,8% at 0,1; 0,5; 1,0 và 2,0 mg/ml theo thứ tự. Sau 6 ngày xử lý với chất chiết xuất của T. nigrovenulossa, tỷ lệ ức chế trứng nở là 65,0; 50,8; 21,7 và 6,7% tại nồng độ 0,1; 0,5; 1,0 và 2,0 mg/ml theo thứ tự. Tỷ lệ gây chết và tỷ lệ ức chế của chất chiết xuất phụ thuộc vào cả thời gian và nồng độ xử lý.
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Collazo, Bigliardi Sofía. "Lignocellulosic fractions from rice and coffee husks to improve functionality of biodegradable films based on starch and poly-lactic acid." Doctoral thesis, Universitat Politècnica de València, 2019. http://hdl.handle.net/10251/123055.
Full textAbstract:
[ES] La presente Tesis Doctoral se ha centrado en el aislamiento y caracterización de materiales celulósicos y extractos activos, procedentes de las cascarillas de arroz y café, y su incorporación a películas de almidón y mezclas compatibilizadas de almidón-PLA, para mejorar sus propiedades funcionales como materiales para el envasado de alimentos.
Las fibras de celulosa (CF) se obtuvieron mediante tratamiento alcalino y de blanqueo, con un rendimiento de 41 y 53 g fibras/100 g cascarilla, respectivamente para cascarilla de arroz y café. Los nanocristales de celulosa (CNC) se aislaron de las fibras mediante hidrólisis ácida, con un rendimiento del 5% respecto a las fibras y con alta cristalinidad (90-92%), resistencia térmica y relación de aspecto (L/d: 20-40). Los compuestos activos se obtuvieron mediante extracción hidrotérmica (180 ºC; 9,5 bares), con un rendimiento de 17-18 g/ 100 g de cascarilla. Dichos extractos exhibieron capacidad antioxidante (EC50: 5,37-5,29 mg sólidos extraídos/ mg DPPH) y antimicrobiana (cuantificada en términos de concentración mínima inhibitoria: MIC) frente a L. innocua (MIC: 48-52 mg polvo/mL) y E. coli (MIC: 50-66 mg polvo/mL).
Los materiales celulósicos procedentes de cascarilla de arroz y café se incorporaron a películas de almidón termoplástico (TPS), obtenidas mediante mezclado en fundido y moldeo por compresión. El módulo elástico aumentó un 186 y 121% cuando se incorporó a la matriz un 1% (p/p) de CNC de cascarilla de arroz y café, respectivamente. Del mismo modo, las CF se añadieron a las películas de TPS al 1, 5 y 10 pt%. Ambas CF aumentaron la rigidez y redujeron la extensibilidad de los films, aunque las CF de cascarilla de café
mantuvieron mejor la ductilidad al 1 y 5% (p/p). La permeabilidad al vapor de agua de las películas de TPS no se redujo en los materiales compuestos, aunque la permeabilidad al oxígeno se redujo en aproximadamente un 17%. Al incorporar extractos activos a los films de almidón, mejoraron sus propiedades de tracción; el módulo elástico aumentó un 350%, a la vez que se hicieron menos extensibles. Las fibras de celulosa de ambos residuos fueron más efectivas como agentes de refuerzo en los films con extractos sólidos que en los de almidón solo.
Se estudiaron también mezclas de almidón-PLA utilizando como compatibilizador policaprolactona funcionalizada con anhídrido maléico y/o glicidil metacrilato (PCLMG o PCLG). Se analizó el efecto de la proporción de PLA en la mezcla (20 y 40% respecto al almidón), y la de ambos compatibilizadores (2,5 y 5%), en las propiedades de los films. Los análisis de la microestructura, el comportamiento térmico y las propiedades funcionales (mecánicas, ópticas y de barrera) de los films, demostraron que sustituir el 20% del almidón por PLA e incorporar el 5% de PCLG podría ser una buena estrategia para obtener materiales adecuados para envasado de alimentos. Además, se estudió el efecto de la adición de rellenos celulósicos (CF y CNC) y del extracto antioxidante de cascarilla de café en la mezcla de almidón-PLA compatibilizada seleccionada. Las propiedades antioxidantes de los films se probaron a través de su eficacia para preservar al aceite de girasol de la oxidación. Se observaron diferencias significativas en las propiedades funcionales de los films cuando los CNC se incorporaron mediante dos métodos diferentes. El efecto de refuerzo de los materiales celulósicos en mezclas de S-PLA fue menos notable que en las películas de almidón, probablemente debido a la superposición del efecto de refuerzo de PLA. El extracto antioxidante no mejoró el comportamiento mecánico en la mezcla, pero le confirió capacidad antioxidante, adecuada para aplicaciones en el envasado de alimentos.[CAT] La present Tesi Doctoral s'ha centrat en l'aïllament i caracteritzaciò de materials cel.lulòsics i extractes actius, procedents de pellorfa d'arròs i café, i la seua incorporació a pel·lícules de midó i mescles compatibilitzades de midò-PLA, per a millorar les seues propietats funcionals com materials per al envasat d'aliments. Les fibres de cel.lulosa (CF) s'obtingueren mitjançant tractament alcalí i de blanqueig, amb un rendiment de 41 i 53 g fibres/100g pellorfa, respectivament per a pellorfa d'arròs i cafè. Els nanocristalls de cel·lulosa (CNC) es van aïllar de les fibres de cel·lulosa per mig d'hidròlosi àcida, amb un rendiment del 5% respecte a les fibres; en tots dos casos, amb alta cristal·línitat (90-92%), resistència tèrmica i relaciò d'aspecte (L/d: 20-40). Els composts actius s'obtingueren mitjançant l'extracció hidrotèrmica (180 ºC; 9,5 bars), amb un rendiment del 17-18 g/100 g de pellorfa. Aquests composts exhibiren capacitat antioxidant (EC50: 5,37-5,29 mg extracte solit/ mg DPPH) i antimicrobiana, (quantificada en termes de concentració mínima inhibitòria: CMC) enfront a L. innocua (MIC: 48-52 mg pols/mL) i E. coli (MIC: 50-66 mg pols/ mL). Els materials cel·lulòsics procedents de pellorfa d'arròs i cafè es van incorporar a pel·lícules de midó termoplàstic (TPS), obtingudes mitjançant mesclat en fos i modelatge per compressió. El mòdul elàstic va augmentar un 186 i 121% quan es va incorporar a la matriu un 1 pt% CNC de pellorfa d'arròs i café, respectivament. De la mateixa manera, les CF es van afegir a les pel·lícules de TPS al 1, 5 i 10 pt%. Ambdues CF va augmentar la rigidesa de les pel·lícules i es va reduir la seua capacitat d'estirament. No obstant, les CF de pellorfa de cafè mantingueren millor la ductilitat al 1 i 5%. La permeabilitat al vapor d'aigua de les pel·lícules de TPS no es va reduir en els materials compostos, encara que la permeabilitat a l'oxigen es va reduir en aproximadament un 17%. A l'incorporar extractes actius a les pel·lícules de midó, milloraren les propietats de tracció de les pel·lícules ; el mòdul elàstic va augmentar un 350%, mentre que les pel·lícules es feren menys extensibles. Les CF dels dos residus foren més efectives com agents de reforç en pel·lícules que contenien extractes actius, que en pel·lícules de midó pur. També es van estudiar mescles de midò-PLA utilitzant com a compatibilitzador policaprolactona funcionalitzada amb anhídrid maleic i/o glicidil metacrilat (PCLMG o PCLG). Es va analitzar l'efecte de la proporció de PLA en la mescla (20 i 40% respecte al midó), i de la tots dues compatibilitzadors (2,5 i 5%), en les propietats de les pel·lícules. Els anàlisis de la microestructura, el comportament tèrmic i les propietats funcionals (mecàniques, óptiques i de barrera) de les pel·lícules, demostraren que substituir el 20% del midó per PLA i incorporar el 5% de PCLG podria ser una bona estratègia per a obtindré pel·lícules adequades per a l'envasat d'aliments. A demés, es va estudiar l'efecte de l'addició de reforçaments cel·lulòsics (CF i CNC) i extracte antioxidant de pellorfa de cafè, en mescles de midó-PLA compatibilitzades. Les propietats antioxidants de les pel·lícules s'analitzaren a través de la seua eficàcia per a preservar de l'oxidació l'oli de gira-sol. S'observaren diferències significatives en les propietats funcionals de les pel·lícules quan els CNC s'incorporaren mitjançant dos mètodes diferents. L'efecte de reforç dels materials cel·lulòsics en mescles de S-PLA va ser menys notable que en les pel·lícules de midó, provablement degut a la superposició de l'efecte de reforç del PLA. L'extracte antioxidant no va millorar el comportament mecànic en les mescles, però li va conferir la capacitat antioxidant adequada per a aplicacions a l'envasat d'aliments.
[EN] This Doctoral Thesis has focused on the isolation and characterisation of cellulosic materials and active extracts from coffee and rice husks, and their incorporation into starch films and starch-PLA compatibilised blend films in order to improve their functional properties as food packaging materials. Cellulose fibres were obtained through alkali and bleaching treatment with a final yield of 41 and 53 g fibres/100 g husk, respectively for rice and coffee husks. Cellulose nanocrystals were isolated from the bleached fibres by acid hydrolysis, with a yield of 5% with respect to bleached fibres, in both cases, with high crystallinity (90-92%), thermal resistance and aspect ratio (L/d: 20-40). The active compounds were obtained by hydrothermal extraction (180 ºC, 9.5 bar) with yields of 17 -18 g/100 g husks. They exhibited antioxidant properties (EC50: 5.37-5.29 mg extract solids/mg DPPH) and antibacterial activity against L. innocua (MIC: 48-52 mg powder/mL) and E. coli (MIC: 50-66 mg powder/mL), which were quantified in terms of the minimal inhibitory concentration. Cellulosic material from rice and coffee husks were incorporated into thermoplastic starch films (TPS) by melt blending and compression moulding. The elastic modulus increased by 186 and 121% when 1 wt% of cellulose nanocrystals (CNC) from rice and coffee husks, respectively, was incorporated into the matrix. Likewise, cellulose fibres (CF) were incorporated into TPS films at 1, 5 and 10 wt%. Both CF increased the film stiffness while reducing its stretchability. However, CF from coffee husk better maintained the film ductility at 1 and 5 wt%. The water vapour permeability of TPS films was not reduced in composites, although oxygen permeability was lowered by about 17%. When active extracts were incorporated into starch films, they improved the tensile properties; the elastic modulus increased by about 350%, while films became less stretchable. The cellulosic fibres from both residues were more effective as reinforcing agents in films containing extract solids than in net starch films. Starch-PLA blend films were also studied using grafted polycaprolactone with maleic anhydride and/or glycidyl methacrylate (PCLMG or PCLG) as compatibilisers. The effect of both the PLA ratio in the blend (20 and 40% with respect to starch) and the amount of both compatibilisers (2.5 and 5%) on the film properties was analysed. The analyses of microstructure, thermal behaviour and functional properties (mechanical, optical and barrier) of the films led to the conclusion that substituting 20% of the starch by PLA, and incorporating 5% of PCLG would be a good strategy to obtain films suitable for food packaging. The effect of the addition of cellulosic fillers (CF and CNC) and antioxidant aqueous extract from coffee husk to compatibilised starch-PLA blends was also studied. The antioxidant properties of the films were tested through their efficacy at preserving sunflower oil from oxidation. Significant differences were observed in the functional properties of the films when CNC was incorporated by two different methods. The reinforcing effect of cellulosic materials in S-PLA blends was less noticeable than in starch films, probably due to the overlapping of the PLA reinforcing effect. The antioxidant extract did not improve the mechanical performance in the blends, but conferred antioxidant capacity suitable for food packaging applications.
Collazo Bigliardi, S. (2019). Lignocellulosic fractions from rice and coffee husks to improve functionality of biodegradable films based on starch and poly-lactic acid [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/123055
TESIS
Books on the topic "Coffee Extract"
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Bagchi, Debasis, Hiroyoshi Moriyama, and Anand Swaroop, eds. Green Coffee Bean Extract in Human Health. Boca Raton : Taylor & Francis, 2017.: CRC Press, 2016. http://dx.doi.org/10.1201/9781315371153.
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Pure green coffee bean extract: The quick start guide to burn fat, avoid green coffee scams and reviews of green coffee beans for weight loss. United States]: [Kate Redwine], 2012.
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Galland, Antoine. De l'origine et du progrès du café: Extrait d'un manuscrit arabe de la Bibliothèque du roi. Paris: Editions La Bibliothèque, 1992.
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Link, D. H. G. Green Coffee Bean Extract. Independently Published, 2019.
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Green Coffee Bean Extract in Human Health. Taylor & Francis Group, 2021.
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Bagchi, Debasis, Hiroyoshi Moriyama, and Anand Swaroop. Green Coffee Bean Extract in Human Health. Taylor & Francis Group, 2016.
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Bagchi, Debasis, Hiroyoshi Moriyama, and Anand Swaroop. Green Coffee Bean Extract in Human Health. Taylor & Francis Group, 2016.
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Bagchi, Debasis, Hiroyoshi Moriyama, and Anand Swaroop. Green Coffee Bean Extract in Human Health. Taylor & Francis Group, 2016.
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Bagchi, Debasis, Hiroyoshi Moriyama, and Anand Swaroop. Green Coffee Bean Extract in Human Health. Taylor & Francis Group, 2016.
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Bagchi, Debasis, and Hiroyoshi Moriyama. Green Coffee Bean Extract in Human Health. Taylor & Francis Group, 2016.
Find full textBook chapters on the topic "Coffee Extract"
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Cardeño Calle, Lukas, and Martha Elena Londoño López. "Green synthesis of silver nanoparticles using green coffee bean extract." In VII Latin American Congress on Biomedical Engineering CLAIB 2016, Bucaramanga, Santander, Colombia, October 26th -28th, 2016, 217–20. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-4086-3_55.
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Pourmasoumi, Makan, Amir Hadi, Wolfgang Marx, Ameneh Najafgholizadeh, Sukhdeep Kaur, and Amirhossein Sahebkar. "The Effect of Green Coffee Bean Extract on Cardiovascular Risk Factors: A Systematic Review and Meta-analysis." In Natural Products and Human Diseases, 323–45. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-73234-9_21.
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Bährle-Rapp, Marina. "Coffea Robusta Extract." In Springer Lexikon Kosmetik und Körperpflege, 123. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_2306.
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Singhara, Apasrin, Carlos Macku, and Takayuki Shibamoto. "Antioxidative Activity of Brewed Coffee Extracts." In ACS Symposium Series, 101–9. Washington, DC: American Chemical Society, 1998. http://dx.doi.org/10.1021/bk-1998-0702.ch011.
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van de Lagemaat, J., C. Augur, and D. L. Pyle. "Screening of Filamentous Fungi for the Production of Extra-Cellular Tannase in Solid State Fermentation (SSF)." In Coffee Biotechnology and Quality, 455–60. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-017-1068-8_43.
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Lasso, Emmanuel, Thiago Toshiyuki Thamada, Carlos Alberto Alves Meira, and Juan Carlos Corrales. "Graph Patterns as Representation of Rules Extracted from Decision Trees for Coffee Rust Detection." In Communications in Computer and Information Science, 405–14. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24129-6_35.
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"Green Coffee Bean Extract." In PharmacotherapyFirst Drug Information. 2215 Constitution Avenue, N.W. Washington, DC 20037-2985: The American Pharmacists Association, 2017. http://dx.doi.org/10.21019/druginformation.green_coffee.
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"Green Coffee Bean Extract." In PharmacotherapyFirst Drug Information. 2215 Constitution Avenue, N.W. Washington, DC 20037-2985: The American Pharmacists Association, 2017. http://dx.doi.org/10.21019/pfdi.green_coffee.
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"Antiobesity Profile of Green Coffee Extract." In Green Coffee Bean Extract in Human Health, 117–31. Taylor & Francis Group, 6000 Broken Sound Parkway NW, Suite 300, Boca Raton, FL 33487-2742: CRC Press, 2016. http://dx.doi.org/10.1201/9781315371153-8.
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"Beneficial Effects of Green Coffee Bean Extract and Coffee Polyphenols on Metabolic Syndrome." In Green Coffee Bean Extract in Human Health, 103–16. Taylor & Francis Group, 6000 Broken Sound Parkway NW, Suite 300, Boca Raton, FL 33487-2742: CRC Press, 2016. http://dx.doi.org/10.1201/9781315371153-7.
Full textConference papers on the topic "Coffee Extract"
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Borompichaichartkul, Chaleeda, Desi Sakawulan, and Richard Archer. "Enhancing antioxidant property of instant coffee by microencapsulation via spray drying." In 21st International Drying Symposium. Valencia: Universitat Politècnica València, 2018. http://dx.doi.org/10.4995/ids2018.2018.7520.
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This study is aimed to improve the antioxidant property of instant coffee by using microencapsulation technique and spray drying. Concentrated coffee extract was mixed with Konjac glucomannan hydrolysate (KGMH) and Maltodextrin (MD). The mixture of coating material and coffee extract was then spray dried at 160 - 180 °C inlet air temperature and at 85-90 °C outlet air temperature. KGMH can preserve retention of phenolic compounds, DPPH scavenging activity and antioxidant activity of FRAP (p<0.05 of instrant coffee better than other treatment. Keywords: Hydrolysed Konjac Glucomannan; Spray Drying; Microencapsulation; Instant Coffee, Antioxidant
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Perera, TVRC, K. Pakeerathan, and A. Nirosha. "ECO-FRIENDLY MANAGEMENT COMMON LAB CONTAMINANT Trichoderma spp IN OYSTER MUSHROOM PRODUCTION USING AGROBASED INDUSTRY’S BY-PRODUCTS." In The 5th International Conference on Climate Change 2021 – (ICCC 2021). The International Institute of Knowledge Management, 2021. http://dx.doi.org/10.17501/2513258x.2021.5105.
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An abundant supply of low-cost substrate and management of green mold disease-causing fungus Trichoderma are the major hurdles in successful mushroom production. This study aimed to identify the best Agro-based industry’s by-products as a substitute for oyster mushroom production (Pleurotus ostreatus) while managing fungal contaminants eco-friendly. Two sets of In-Vitro [containing 20% extracts, from agro-based industries, such as coffee waste powder, tea dust and Mahua oil cake] and In-Vivo experiments [four substrates such as paddy straw, wood sawdust, paddy husk and banana leaves were incorporated with coffee powder, tea dust and Mahua oil cake] were prepared separately. All the experiments were conducted using a complete randomized design with three replicates. The In-Vitro data [mycelial growth and sporulation of both fungi], In-Vivo data [mycelial mushroom run, pinhead formation and yield] were subjected to ANOVA and DMRT mean separation using SAS 9.1 statistical package at P <0.05. In-Vitro results showed that the Trichoderma mycelial growth was significantly minimum in Mahua (2.5 cM) and coffee (3.6 cM) in comparison to control, whereas, with decreasing concentration of coffee, tea, and Mahua extract P. ostreatus showed enhanced growth. Trichoderma sporulation had significantly affected coffee treatment, and even not sporulate in Mahua treated plants. The In-Vivo experiment proved that spawn run was consistent and significant among the treatments when mixed tea (20 days) and coffee (21 days), respectively, at P <0.05. Treatment wise coffee treated spawn bags took an average of 32.5 days, whereas, in tea-treated substrates, it was more than 36 days to form pinhead. Mahua treated trials showed poor spawn run in all substrates, longer days of pinhead formation, and lower yield. In contrast, the paddy straw + coffee treatment produced a significantly highest yield of 200.67g. When sawdust was the substrate, the addition of tea showed a significantly higher yield of 185.00g than coffee (145.00g). In conclusion, coffee and tea extracts have a significant effect on yield with paddy straw and sawdust while minimizing the growth of Trichoderma. Keywords: Pleurotus ostreatus, eco-friendly, plant extract, substrate, coffee, paddy straw
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Citraningrum, Irmaziza, Anjar Ruspita Sari, Annie Mufyda Rahmatika, Iman Sabarisman, and Satria Bhirawa Anoraga. "Effect of Extract Concentration of Robusta Coffee (Coffea canephora) Husk Extract and Cooking Temperature on Quality Characteristics of Hard Candy." In International Conference on Sustainable Environment, Agriculture and Tourism (ICOSEAT 2022). Paris, France: Atlantis Press, 2022. http://dx.doi.org/10.2991/978-94-6463-086-2_38.
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Hilda, Damayanti, Aprilliani Arini, and Clarissa D. Nancy. "Formulation of Body Scrub Cream From Extract of Arabika Green Coffee (Coffea arabica L.) as Antioxidant." In 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020). Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/ahsr.k.210115.071.
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Audina, Anggi, Kiki Nurtjahja, and Albert Pasaribu. "The Potential Methanolic Extract of Coffee Leaves (Coffea canephora L.) in Inhibiting Storage Fungi and Yeast." In The International MIPAnet Conference on Science and Mathematics (IMC-SciMath). SCITEPRESS - Science and Technology Publications, 2019. http://dx.doi.org/10.5220/0010612500002775.
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Dat, Lai Quoc, and Nguyen Thi Ngoc Quyen. "Nanofiltration for concentration of roasted coffee extract: From bench to pilot." In INTERNATIONAL CONFERENCE ON CHEMICAL ENGINEERING, FOOD AND BIOTECHNOLOGY (ICCFB2017): Proceedings of the 3rd International Conference on Chemical Engineering, Food and Biotechnology. Author(s), 2017. http://dx.doi.org/10.1063/1.5000176.
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Handayani, Dewi Ratih, Aditya Gilang Nur Pratama, and I. Wayan Agus Putra. "Effect of Ethanol Extract of Robusta Coffee (Coffea canephora) on the Function of the Liver and Kidney of Wistar Rat." In 12th Annual Scientific Meeting, Medical Faculty, Universitas Jenderal Achmad Yani, International Symposium on "Emergency Preparedness and Disaster Response during COVID 19 Pandemic" (ASMC 2021)). Paris, France: Atlantis Press, 2021. http://dx.doi.org/10.2991/ahsr.k.210723.017.
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Maryana, Erma, Endang Saepudin, and Noer Laily. "The potency of chlorogenic acid extract from green coffee beans on inhibition pancreatic lipase activity." In 3RD INTERNATIONAL CONFERENCE ON CHEMISTRY, CHEMICAL PROCESS AND ENGINEERING (IC3PE). AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0062466.
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Dewi, Tyas Soemarah Kurnia, Haryuni Supartini, Endang Suprapti, Sapto Priyadi, Didik Dwi Ardiyanto, Achmadi Priyatmojo, and Misri Gozan. "Effect of Nicotiana tabacum Extract Concentration as Biopesticide on protein content of Robusta coffee beans and skin." In Proceedings of the International Conference on Science and Education and Technology 2018 (ISET 2018). Paris, France: Atlantis Press, 2018. http://dx.doi.org/10.2991/iset-18.2018.114.
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Mayorga-Yuntul, Francisco, Meliza Lindsay Rojas, and Guillermo Linares. "Substitution of Wheat Flour for Spent Coffee Grounds Extract: Antioxidant Activity, Sensory Characteristics, and Color of Sweet Biscuits." In 20th LACCEI International Multi-Conference for Engineering, Education and Technology: “Education, Research and Leadership in Post-pandemic Engineering: Resilient, Inclusive and Sustainable Actions”. Latin American and Caribbean Consortium of Engineering Institutions, 2022. http://dx.doi.org/10.18687/laccei2022.1.1.768.
Full textReports on the topic "Coffee Extract"
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Kim, Jihee, Sun Hee Moon, and Dong Uk U. Ahn. Antioxidant Effect of Extracts from the Coffee Residue in Raw and Cooked Meat. Ames (Iowa): Iowa State University, January 2018. http://dx.doi.org/10.31274/ans_air-180814-360.
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LOW-CYCLE FATIGUE PROPERTIES OF AUSTENITIC STAINLESS STEEL S30408 UNDER LARGE PLASTIC STRAIN AMPLITUDE. The Hong Kong Institute of Steel Construction, March 2022. http://dx.doi.org/10.18057/ijasc.2022.18.1.10.
Full textAbstract:
The application of stainless steel materials in civil structures for seismic protection lies in its low-cycle fatigue characteristic. However, the data of existing research are mainly based on the low-cycle fatigue in small strain amplitudes. To this end, we perform low-cycle fatigue testing of Austenitic stainless steel S30408, which has low yield point and good elongation performance, under the cyclic load with a maximum strain amplitude reaching up to 5%, to fill the gap. The stress-strain response characteristics of the stainless steel material under the cyclic load are analyzed; then, the parameters of the strain-fatigue life relationship and the cyclic-plastic constitutive model used for FEA simulation are extracted. Results show that the stainless steel’s stress-strain curve is nonlinear without a yield plateau, thus presenting a high strength yield ratio and ductility. The hysteresis loops of the material are plump with a shuttle shape and are symmetric to the origin, indicating a fine energy dissipation capacity. The skeleton curve under cyclic loading with cyclic hardening can be significantly reflected by the Ramberg Osgood model, which is affected by the strain amplitude and loading history; it is also different from the monotonic tensile skeleton curve. The strain-fatigue life curve fitted by the Baqusin Manson Coffin model can predict the materials’ fatigue life under different strain amplitudes. The mixed hardening model, including isotropic and kinematic hardening, based on the Chaboche model, is able to simulate the cyclic stress-strain relationship. Further, its parameters can provide basic data information for the seismic design of civil structures when Austenitic stainless steel S30408 is used.