Academic literature on the topic 'Co-adaptation (informatique)'

The expansion of green infrastructure through vertical forms of greenery is an innovative way to address urban sustainability challenges. Despite various social, economic, and environmental benefits, however, facade greening is rarely implemented. This article examines barriers to and solutions for the implementation of green facades through a systematic literature review and a participatory case study of Leipzig, Germany. We found a total of 24 social, political-administrative, economic, practical-technical, and environmental barriers hindering key actors to (successfully) implement green facades. The lack of information and knowledge was found to be an underlying issue. Solutions co-created with local stakeholders and experts include the provision of informative, regulatory, and financial incentives, the adaptation of political-administrative strategies, regulations, and procedures, as well as the support of the practical-technical implementation process through information and experts. To overcome barriers, various measures must be combined, but establishing public relations and advisory services on green facades is of priority in Leipzig. By combining insights from academic literature with applied knowledge of a diverse group of local actors, we identify how barriers to facade greening may be overcome in the specific case of a major German city and provide a blueprint for similar research in other socio-political contexts.

The experiment was conducted at three different locations of Bangladesh Agricultural Research Institute viz., at PRC, Ishurdi, Pabna, at PRSS, Joydebpur, Gazipur and RARS, Jashore, during the period November to March in 2014-15 and 2015-16. The experiment was laid out in Randomized Complete Block Design with three replications. Variance analysis showed significant interaction between genotype and environment on yield and its related traits. The highest yield was recorded in genotypes BARI Masur-7 followed by BARI Masur-6, BARI Masur-5, BARI Masur-4 and the lowest was in BLX-66004-12. The PCA (Principal component analysis) scores of a genotype in the GGE analysis indication of the stability or adaptation over environments. GGE biplot analysis related that the PC1 and PC2 for different traits, i.e. 80.8% and 11.7% for days to flowering, 72.4% and 18.7% for days to maturity, 66.3% and 15.4% for plant height, 73.8% and 17.3% for pods/plant, 70.1% and 22.8% for 100 seed weight and 38.37% and 31.04% for yield of the total variation, respectively. Considering regression co-efficient values and also biplot analysis most stable variety was BARI Masur-4 followed by BARI Masur-5 and BARI Masur-6 and lowest stable variety was BLX-05002-6. Among the six environments, Ishurdi 2014-15 and Gazipur 2014-15 were most discriminating (informative) and Jashore 2014-15 and Jashore 2015-16 were less discriminating. Among two years (2014-15 and 2015-16) at different location 2015-16 was found favorable for lentil production. Bangladesh J. Agril. Res. 46(3): 307-320, September 2021

Purpose. The main purpose of the article is the analysis of the phenomenon and manifestations of the somatic transformations in the context of anthropo-technological evolution at the beginning of the XXI century. Theoretical basis. The author determines the understanding of the concept "somatic transformations" in the frames of anthropotechnogynesis is possible only on the base of integrative approach and combination of post-non-classical scientific paradigm methodology, theory of the technological development, ideas of trans-humanism, informative society concepts, and net technologies influence on the identity of the human being with robots in the sphere of bioethics and nanoethics, the ethics of new technologies and legal documents which are regulating the processes of technotransformation of the human being. Originality. The author has proved on the example of analysis of the somatic transformations own psychosomatics as he solves some important global in the context of anthropotechnogynesis that a person with help of technological enlargement of and branch problems, so he is trapped of alienation in the very crucial stage, loses the identity and crashes the corporeality in his self. Conclusions. As evidenced by the given analysis, at the modern stage the anthropotechnogynesis is followed by the large-scale quantitative and qualitative somatic transformations based on NBIC-convergence, as a result, a new anthropological subspecies – Homo technologicus appears. All these transformations are a regular stage of evolution, which confirms the thesis of the essential and functional connection of technology with the human body, which are in a relationship of "mutual provocation". In the base of the paradigmatic ontological and anthropological shift which has been on the modern stage, lies the idea of continuity of anthropotechnological co-evolution of the human body and its environment which projects itself in psychosomatic human structure, making a transformation program for better adaptation in technonanobeing. The convergence of human life and techno-existence is a platform for somatic transformations. They are divided into two main groups: intra-structural, substantial, related to techno-modification of the human body directly through biotechnology and genetic engineering, cyborgization, xenotransplantation, Hi-Hume connection with Hi-Tech and others, and external-contextual, when under the influence of pancommunication and hybridization the environment is increasingly mentalized and somatized, and modern technologies are gradually transformed into the social body of man.

The aim of the article is to highlight peculiarities of public libraries activity in Odesa region, taking into account the martial state conditions, and paying special attention to the main directions of their work processes since the full-scale invasion of Russian troops. The methodology of this research is based on general scientific principles of theory and practice unity, systematicity and complexity of cognition. In order to achieve the set goal, the usage of methods on research empirical and theoretical levels has been applied: general scientific methods (description, analysis, synthesis, comparison, generalisation), and special ones (information collecting and processing of the selective observation, content analysis). The scientific novelty of this study grounds on the generalisation and systematisation of new and certain data about public libraries activity in Odesa region in martial state conditions. Сonclusions. It is confirmed that in conditions of full-scale invasion, as well as war with Russia in total, public libraries of Odesa region, essentially, have transformed into important foundations of life activity in OTC (Odesa territorial communities), media- and cultural centres, territories of co-creation, understanding, psychological comfort and security owing to support of communities and other colleagues by interest. It has been shortly described that overcoming the serious challenges and threats, nowadays, public libraries space of the region is positioned not only as a space of enlightenment and tolerance, culture, science and education, but also as a national-patriotic and anti-crisis hub of support, consolidation and growth of the social and human capital. The attention is put on the fact that during the war public libraries stand in solidarity with communities, use all efficient forms and methods of cooperation for helping communities relying on their own work developments and experience. It has been determined that in the aspect of cooperation with local self-government structures, public libraries of Odesa region actively promote the formal and non-formal education, self-education and community progress, as well as popularise reading and give access to the book fund, perform their functions as cultural centres (lectures, discussions with different specialists, book exhibitions, master-classes, creative meetings, etc.), conduct events and classes of national patriotic education, support the Armed Forces of Ukraine, provide informative and consulting support, help refugees and internally displaced people with all possible fast adaptation to the new place and integration into the local community.

Introduction: Multiple myeloma (MM) is a heterogeneous malignancy of clonal plasma cells that accumulate in the bone marrow (BM). Despite new treatment approaches, in most patients resistant subclones are selected by therapy, resulting in the development of refractory disease. While the subclonal architecture in newly diagnosed patients has been investigated in great detail, intra-tumor heterogeneity in relapsed/refractory (RR) MM is poorly characterized. Recent technological and computational advances provide the opportunity to systematically analyze tumor samples at single-cell (sc) level with high accuracy and througput. Here, we present a pilot study for an integrative analysis of sc Assay for Transposase-Accessible Chromatin with high-throughput sequencing (scATAC-seq) and scRNA-seq with the aim to comprehensively study the regulatory landscape, gene expression, and evolution of individual subclones in RRMM patients. Methods: We have included 20 RRMM patients with longitudinally collected paired BM samples. scATAC- and scRNA-seq data were generated using the 10X Genomics platform. Pre-processing of the sc-seq data was performed with the CellRanger software (reference genome GRCh38). For downstream analyses the R-packages Seurat and Signac (Satija Lab) as well as Cicero (Trapnell Lab) were used. For all patients bulk whole genome sequencing (WGS) data was available, which we used for confirmatory studies of intra-tumor heterogeneity. Results: A comprehensive study at the sc level requires extensive quality controls (QC). All scATAC-seq files passed the QC, including the detected number of cells, number of fragments in peaks or the ratio of mononucleosomal to nucleosome-free fragments. Yet, unsupervised clustering of the differentially accessible regions resulted in two main clusters, strongly associated with sample processing time. Delay of sample processing by 1-2 days, e.g. due to shipment from participating centers, resulted in global change of chromatin accessibility with more than 10,000 regions showing differences compared to directly processed samples. The corresponding scRNA-seq files also consistently failed QC, including detectable genes per cell and the percentage of mitochondrial RNA. We excluded these samples from the study. Analysing scATAC-seq data, we observed distinct clusters before and after treatment of RRMM, indicating clonal adaptation or selection in all samples. Treatment with carfilzomib resulted in highly increased co-accessibility and >100 genes were differentially accessible upon treatment. These genes are related to the activation of immune cells (including T-, and B-cells), cell-cell adhesion, apoptosis and signaling pathways (e.g. NFκB) and include several chaperone proteins (e.g. HSPH1) which were upregulated in the scRNA-seq data upon proteasome inhibition. The power of our comprehensive approach for detection of individual subclones and their evolution is exemplarily illustrated in a patient who was treated with a MEK inhibitor and achieved complete remission. This patient showed two main clusters in the scATAC-seq data before treatment, suggesting presence of two subclones. Using copy number profiles based on WGS and scRNA-seq data and performing a trajectory analysis based on scATAC-seq data, we could confirm two different subclones. At relapse, a seemingly independent dominant clone emerged. Upon comprehensive integration of the datasets, one of the initial subclones could be identified as the precursor of this dominant clone. We observed increased accessibility for 108 regions (e.g. JUND, HSPA5, EGR1, FOSB, ETS1, FOXP2) upon MEK inhibition. The most significant differentially accessible region in this clone and its precursor included the gene coding for krüppel-like factor 2 (KLF2). scRNA-seq data showed overexpression of KLF2 in the MEK-inhibitor resistant clone, confirming KLF2 scATAC-seq data. KLF2 has been reported to play an essential role together with KDM3A and IRF1 for MM cell survival and adhesion to stromal cells in the BM. Conclusions: Our data strongly suggest to use only immediately processed samples for single cell technologies. Integrating scATAC- and scRNA-seq together with bulk WGS data showed that detection of individual clones and longitudinal changes in the activity of cis-regulatory regions and gene expression is feasible and informative in RRMM. Disclosures Goldschmidt: John-Hopkins University: Research Funding; Novartis: Membership on an entity's Board of Directors or advisory committees, Research Funding; John-Hopkins University: Research Funding; Bristol-Myers Squibb: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Mundipharma: Research Funding; Takeda: Membership on an entity's Board of Directors or advisory committees, Research Funding; MSD: Research Funding; Molecular Partners: Research Funding; Dietmar-Hopp-Stiftung: Research Funding; Janssen: Consultancy, Research Funding; Chugai: Honoraria, Research Funding; Janssen: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Sanofi: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Amgen: Consultancy, Research Funding; Celgene: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Adaptive Biotechnology: Membership on an entity's Board of Directors or advisory committees.

Abstract Water uptake by roots is a key adaptation of plants to aerial life. Water uptake depends on root system architecture (RSA) and tissue hydraulic properties that, together, shape the root hydraulic architecture. This work investigates how the interplay between conductivities along radial (e.g. aquaporins) and axial (e.g. xylem vessels) pathways determines the water transport properties of highly branched RSAs as found in adult Arabidopsis (Arabidopsis thaliana) plants. A hydraulic model named HydroRoot was developed, based on multi-scale tree graph representations of RSAs. Root water flow was measured by the pressure chamber technique after successive cuts of a same root system from the tip towards the base. HydroRoot model inversion in corresponding RSAs allowed us to concomitantly determine radial and axial conductivities, providing evidence that the latter is often overestimated by classical evaluation based on the Hagen-Poiseuille law. Organizing principles of Arabidopsis primary and lateral root growth and branching were determined and used to apply the HydroRoot model to an extended set of simulated RSAs. Sensitivity analyses revealed that water transport can be co-limited by radial and axial conductances throughout the whole RSA. The number of roots that can be sectioned (intercepted) at a given distance from the base was defined as an accessible and informative indicator of RSA. The overall set of experimental and theoretical procedures was applied to plants mutated in ESKIMO1 and previously shown to have xylem collapse. This approach will be instrumental to dissect the root water transport phenotype of plants with intricate alterations in root growth or transport functions.

This review summarizes the current knowledge on the major histocompatibility complex (MHC) of the family Felidae. This family comprises an important domestic species, the cat, as well as a variety of free-living felids, including several endangered species. As such, the Felidae have the potential to be an informative model for studying different aspects of the biological functions of MHC genes, such as their role in disease mechanisms and adaptation to different environments, as well as the importance of genetic diversity for conservation issues in free-ranging or captive populations. Despite this potential, the current knowledge on the MHC in the family as a whole is fragmentary and based mostly on studies of the domestic cat and selected species of big cats. The overall structure of the domestic cat MHC is similar to other mammalian MHCs following the general scheme “centromere-MHC class I-MHC class III-MHC class II” with some differences in the gene contents. An unambiguously defined orthologue of the non-classical class I HLA-E gene has not been identified so far and the class II DQ and DP genes are missing or pseudogenized, respectively. A comparison with available genomes of other felids showed a generally high level of structural and sequence conservation of the MHC region. Very little and fragmentary information on in vitro and/or in vivo biological functions of felid MHC genes is available. So far, no association studies have indicated effects of MHC genetic diversity on a particular disease. No information is available on the role of MHC class I molecules in interactions with Natural Killer (NK) cell receptors or on the putative evolutionary interactions (co-evolution) of the underlying genes. A comparison of complex genomic regions encoding NK cell receptors (the Leukocyte Receptor Complex, LRC and the Natural Killer Cell Complex, NKC) in the available felid genomes showed a higher variability in the NKC compared to the LRC and the MHC regions. Studies of the genetic diversity of domestic cat populations and/or specific breeds have focused mainly on DRB genes. Not surprisingly, higher levels of MHC diversity were observed in stray cats compared to pure breeds, as evaluated by DRB sequencing as well as by MHC-linked microsatellite typing. Immunogenetic analysis in wild felids has only been performed on MHC class I and II loci in tigers, Namibian leopards and cheetahs. This information is important as part of current conservation tasks to assess the adaptive potential of endangered wild species at the human-wildlife interface, which will be essential for preserving biodiversity in a functional ecosystem.

Crucial for the research on adaptiogenesis of introduced coniferous species is the study the anatomical structure of their vegetative organs, especially the needles, which provides the productivity of individual trees and plantings in general. In conditions of anthropogenic pressure of the environment there are changes in the thickness and structure of the histological elements of vegetative organs of coniferous species, in the first place, protective tissues. Therefore, the study of the anatomical structure of the needles is relevant in the context of studying the ways and mechanisms of adaptation of gymnosperms to industrial emissions and the finding sensitive phytoindicators of environmental pollution and the condition of coniferous plants in man-made zones. However, today the chronic effect of phytotoxicants on the anatomical structure of needles is insufficiently studied. Ecological and anatomical studies of P. pungens in the conditions of the steppe zone of Ukraine for the effects of technogenesis are practically absent. Prydniprovsk TPP is the largest source of pollution in the city of Dnipro (Ukraine): its emissions make up 68,9 % of the volume of toxic compounds of all enterprises and transport facilities. The main pollutants of emissions from Prydniprovsk TPP are SO2, NO2, solids, CO. In order to reduce the negative impact of the TPP emissions, green plantations mainly from softwood are created around it, which purify the atmosphere and improve the environment throughout the year. In view of this, the purpose of the work is to analyse the state of morphological and anatomical indices of the Picea pungens Engelm f. glauca Beissn. needles under the influence of emissions from Prydniprovsk TPP. The research is conducted according to generally accepted methods (Zlobin et al., 2009; Albrechtova, 2003; Permjakov, 1988). It has been found that the length and weight of needles in experimental specimens of P. pungens decrease with respect to the values of these indices in plants of relatively pure zone; therefore, they are sensitive growth parameters to the action of environmental pollution. Nevertheless, the intensity of the growth of P. pungens needles does not change; therefore, it is not an informative feature for assessing the living conditions of the prickly fir in the industrial zone. The analysis of the micromorphological features of P. pungens needles showed resistance to anthropogenic pressure of its characteristics, such as width and thickness, although the area of needles decreases, which is associated with a significant decrease in the technogenic conditions of the environment of its length. In plants of P. pungens, growing on the territory adjacent to Prydniprovsk TPP, the size of the constituents of needles of P. pungens (epidermis and hypoderms), as well as the number, diameter and type of placement of resin passages in the mesophyll of the needles do not differ significantly from such indices in plants of relatively pure zone indicating the stability of these features and the resistance of the needles of the investigated species to the emissions of TPP. The thickness of the assimilation parenchyma from the adaxial side of the needle of P. pungens in the conditions of technogenesis increases. Among the histological elements of the needles P. pungens the greatest influence of man-made emissions is experienced by the components of the central conductive cylinder: the layer of endoderm thickens by 15,9 %, as compared with the control value, which we consider as an adaptive reaction of plants to man-made stress; the diameter of the central conductive cylinder and the thickness of xylem increases. Probably this is due to the need for better water supply of plants. Thus, in the conditions of technogenesis, stability of the histological characteristics and plasticity of the morphometric characteristics of the needles P. pungens were revealed. The formation of adaptive mechanisms of compensatory type in the needles of P. pungens under the influence of phytotoxicants was found: there is an increase of the size of the endoderm, mesophyll, xylem and the central conductive cylinder of the needles. It is shown that the ratio of particles of histological structures of needles (in %) to the action of pollutants of TPP remains practically unchanged. The informative test parameters for monitoring studies of the condition of coniferous plants in man-made zones (mass, length and area of needles) are suggested. Estimation of P. pungens resistance to the components of the thermal power plant's emissions as a medium-resistant species. It is recommended to use P. pungens in landscaping of contaminated areas.

Screens, as technological but also narrative and social devices, alter reading and writing practices. Users consume vids, read stories on the Web, and produce creative contents on blogs or Web archives, etc. Uses of seriality and transmediality are here discussed, that is watching, reading, and writing as interpreting, as well as respective and reciprocal uses of iteration and interaction (with technologies and with others). A specific figure of users or readers will be defined as a skilful and literate audience: fans on archives (FanFiction.net-FFNet, and Archive of Our Own-AO3). Fans produce serial and transmedia narratives based upon their favourite TV Shows, publish on-line, and often produce discourses or meta-discourse on this writing practice or on writing in general.The broader perspective of reception studies allows us to develop a three-step methodology that develops into a process. The first step is an ethnographic approach based on practices and competencies of users. The second step develops and clarifies the ethnographic dimension into an ethno-narrative approach, which aims at analysing mutual links between signs, texts, and uses of reading and writing. The main question is that of significance and meaning. The third step elaborates upon interactions in a technological and mediated environment. Social, participative, or collaborative and multimodal dimensions of interacting are yet regarded as key elements in reshaping a reading-writing cultural practice. The model proposed is a socio-narrative device, which hangs upon three dimensions: techno-narrative, narratological, and socio-narrative. These three dimensions of a shared narrative universe illustrate the three steps process. Each step also offers specific uses of interacting: an ethnographic approach of fictional expectation, a narrative ethnography of iteration and transformation, and a socio-narrative perspective on dialogism and recognition. A specific but significant example of fans' uses of reading and interacting will illustrate each step of the methodology. This qualitative approach of individual uses aims to be representative of fans' cultural practice (See Appendix 1). We will discuss cultural uses of appropriation. How do reading, interpreting, writing, and rewriting, that is to say interacting, produce meaning, create identities, and build up our relation to others and to the (story)world? Given our interest in embodied and appropriated meanings, appropriation will be revealed as an open cultural process, which can question the conflict and/or the convergence of the old and the new in cultural practices, and the way former and formal dichotomies have to be re-evaluated. We will take an interest in the composition of meaning that unfolds a cultural and critical process, from acknowledgement to recognition, a process where iteration and transformation are no longer opposites but part of a continuum.From Users' Competencies to the Composition of Narrative and Social Skills: A Fictional ExpectationThe pragmatic question of real uses steers our approach toward reading and writing in a mediated environment. Michel de Certeau's work first encourages us to apply his concepts of strategies and tactics to institutional strategies of engaging the audience and to real audience tactics of appropriation or diversion. Real uses are traceable on forums, discussions groups, weblogs, and archives. A model can be built upon digital tracks of use left on fan fiction archives: types of audience, interactions, and types of usage are here considered.Media Types Interaction Types Usage Types Media audienceConsumerSkilfulViewingReadingInformation searchContent production (informative, critical, and creative)Multimedia audienceConsumerSkilful+Online readingE-shoppingSharingRecommendationDiscussionInformative content productionCross-media audienceConsumerSkilful+SerendipityPutting objects in perspectiveNetworkingCritical content productionTransmedia audienceConsumerSkilfulInvolvedPrecursor+Understanding enhanced narrativesValue judgments, evaluationUnderstanding economic dimensions of the media systemCreative content productionTable 1 (Cailler and Masoni Lacroix)Users gear their reading and writing practices toward one medium, or toward multiple media in multi-, cross-, and trans- dimensions. These dimensions engage different and specific kinds of content production, and also the way users think about their relation to the media system. We focus on cumulative uses needed in an evolving media system. Depending on their desire for cultural products issued from creative and entertainment industries, audiences can be consumer-oriented or skilful, but also what we term "involved" or "precursor." Their interactive capacity within these industries allows audiences to produce informative, narrative, discursive, creative (or re-creative), and critical content. An ethnographic approach, based upon uses, understands that accumulating, crossing, and mastering different uses requires available and potential competencies and literacies, which may be immediately usable, or which have to be gained.Figure 1 (Masoni Lacroix and Cailler)The English language enables us to use different words to specify competencies, from ability to skill (when multiple abilities tend towards appropriation), to capability and competency (when multiple skills tend towards cultural practice). This introduces an enhancement process, which describes the way users accumulate and cross competencies to enhance their capability of understanding a multimedia or transmedia system, shaped by multiple semiotic systems and literacies.Abilities and skills represent different literacies that can be distributed in four groups-literacy, graphic literacy, digital literacy and interactive literacy, converging to a core of competencies including cognitive capability, communicative capability, cultural capability and critical capability. Note that critical skills appear below in bold italics. Digital LiteracyTechnical ability / Computational ability / Digital ability or skill Informational skill Visual LiteracyGraphic abilityVisual abilitySemiotic skillSymbolic skill Core of CompetenciesCognitive capabilityCommunicative capabilityCultural capabilityCritical capability Interactive LiteracyInteractional abilitySpectatorial abilityCollective abilityAffective skill LiteracyNarrative ability or skill / Linguistic ability / Reading and interpreting ability / Mimetic and fictional ability Discursive skillTable 2 (Masoni Lacroix and Cailler)Our first illustration exhibits the diversity, even the profuse and confused multiplicity, of cultural influences and preferences of a fan, which he or she comprehends as a whole.Gabihime, born on 6 October in Lafayette, Louisiana, in the United States, joined FFNet in 2001, and last updated her profile in September of 2010. She has written 44 stories for a variety of fandoms, and she belongs to two fandom communities. She has written one story about Twin Peaks (1990-) for an annual fandom gift exchange in 2008. Within Twin Peaks, her favourite and only romantic pair is Audrey Horne and Dale Cooper. Pairing represents a formal and cultural use of fan fiction writing, and also a favourite variation of the original text. Gabihime proposes notes to follow the story:I love Twin Peaks, and I love Audrey Horne particularly, and the rich stilted imagery of the show certainly […] I started watching my favourite season one episodes and reading the script notes for them. When I got to the 4-5 episode break (when Cooper comes back from visiting Jacques's cabin to the delightful sounds of the Icelandic junket roaring at their big shindig and finds Audrey in his bed) I discovered that this scene was originally intended to be left extremely ambiguous.Two main elements can be highlighted. Love founds fans' relation to the characters and the text. Interaction is based on this affect or emotion. Ambiguity, real or presumed, leads to what can be called a fictional expectation. This strong motive to interact within a text means that readers have to fill in the blanks of the text (Jenkins, "Transmedia"). They fill it with their desire for a character, a pairing, and a story. Another illustration of a fan's affective investment, Lynzee005 (see below) specifies that her fiction, "shows what I hope happened in between the scenes to which we were treated in the series."Gabihime does not write fan fiction stories anymore. She has a web site where she posts her stories and links to other fan art, vids, or fiction, as well as a blog where she writes her original fiction, and various meta-narrative and/or meta-discursive productions, including a wiki, Tumblr account, LiveJournal page, and Twitter account.A Narrative Ethnography of Fans' Production Content: Acculturation as Iteration and TransformationWe can briefly focus on another partial but significant example of narratives and discourses of a fan, in the perspective of a qualitative and iterative approach. We will then emphasise that narratives and discourses circulate, in other words that they are written and reformulated in and on different periods and platforms, but also that narratives use iteration and variation (Eco 1985).Lynzee005 was born in 1985 in Canada. She joined FFNet in 2008 and last updated her profile in September 2015. She has a beta profile, which means that she reads and reviews other fans' work-in-progress. We can also clarify that publishing chapter-by-chapter and being re-read on FFNet appears to be a principle of writing and of writing circulation. So, writing reveals an iterative and participative practice.Prior to this updating she wrote:When I read, I look for an emotional connection with the characters and I hope to be genuinely invested in where the story is going. […] I tackle everything in chunks, concentrating on the big issues (consistent characterization, believable plot lines, etc.) before moving down to the smaller ones (spelling, punctuation). Once I finish reading a "chunk," I put it together in the whole and see if it works against the other "chunks," and if not, then I go back and start over.She has written 17 stories for 7 different fandoms. She wrote five stories for Twin Peaks including a crossover with another fandom. She joined AO3 in December 2014 and completed her Twin Peaks trilogy. Her profile no longer underlines this serial process of chunking and dispersal, stressed by Jenkins ("Transmedia"), but only evokes how scenes can be stitched together. She now insists on the outcome of unity or continuity rather than on the process of serialization and fragmentation.Stories about fans, their affective and interpretive relations to a story universe and their uses of reading and writing in and out a fandom, can illustrate a diversity of attachments and interests. We can briefly describe a range of attachments. Attachment to the character, described above, can move towards self-narration, to the exhibit of self both as a person and a character, to a self-distancing, an identity affect. Attachment also has interpretative and critical dimensions. Attached to a narrative universe, attached to storytelling, fans promote a writing normalisation and a narrative format (genre, pairing, tagging, memes, etc.). Every fan seems to iterate and alter this conduct. This appropriation renews self-imposed narrative codes. The use of writing by fans, based on attachments, is both iterative and transformative. The Organization for Transformative Works (OTW), AO3's parent apparatus, asserts that derivative fans' work is transformative.According to Umberto Eco's vision of a postmodern aesthetics of seriality, "Something is offered as original and different […] this something is repeating something else that we already know; and […] just because of it we like it" (167). There is an "enjoyment of variations" (174). "Seriality and repetition are not opposed to innovation" (175). Eco claims a dialectic between repetition and innovation, that is to say a: "dialectic between order and novelty -in other words, between scheme and innovation," where "the variation is no longer more appreciable than the scheme" (173). We acknowledge the "inseparable knot of scheme-variation" he is stressing (Eco 180), and we intend to put narrative fragmentation and narration dispersal forward to their reconstruction in a narrative universe as a whole, within the socio-narrative device. The knot illustrates the dialogical principle of exceeding dichotomies that will be discussed hereunder.The plurality of uses and media calls for an accumulation of competencies, which engage users in the process of media acculturation. A "literate" or skilful user should be able to comprehend "the flow of content across multiple media platforms," the media industries' cooperation, "the migratory behavior of media audiences," and the "technological, industrial, cultural, and social changes" that the word convergence manages to describe (Jenkins, Convergence, 3).Acculturation conveys an appropriation process, borrowed from "French" sociology of uses. Audiences become gradually intimate with the context of the evolving media environment. Scholars progressively understand how audiences are familiarizing themselves with competencies until they master literacies, where competencies are gathered. Users become sensitive, as well as mindful of time and space in literacy (Literacy), and of how writing can be spatialised (Graphic Literacy), of how the media space is technologized (Digital Literacy), and of what kind of structural interactions are emerging (Interactive Literacy).Thus, the research question takes shape: "What kind of interactions can users establish with objects that are both technical and cultural?" Which also means: "In a study of effective uses, can the researcher find appropriation logics or tactics in the way users, specifically here readers and writers, improve their cultural practices?" As Davallon and Le Marec furthered it, uses have to be included in a process of cultural growth. Users can cross technical and cultural dimensions of an object in two main ways: They can compare the object with other cultural products they are used to, or they can grasp its novelty when engaging a cognitive and cultural capability of adaptation. Acknowledgment and adaption are part of the social process of cultural growth. In this sense, use can be an integrated activity or a novel one.The model of cultural growth means that different and dispersed uses are progressively entering a meaning-making process. The question of meaning holds together, even unifies, multiple uses of reading and writing in a cultural practice of reading-writing. With this in mind, the core of competencies described above accurately displays the importance of critical skills (semiotic, informational, affective, symbolic, narrative, and discursive) nourishing a critical capability. Critically literate, users are able to question the place to which they have been attributed and the place they can gain, in an evolving (and even uncertain) media system. They can elaborate a critical reflection on their own practices of reading and writing.Two Principles of a Socio-Narrative Device: Dialogism and RecognitionUses of reading and writing online invite us to visualize and think through the convergence of a narrative object (technical, visual, and cultural), its medium and format(s), and the audiences involved. Here, multimodality has to be (re)considered. This is not only a question of different modes but a question of multiplicity in reading and writing uses, that leads us to the way a fan attachment creates his or her participation in the meaning of the text, and more generally leads us to the polyphonic form of writing questions. Dispersed uses converging into a cultural and social practice bring to light dialogical dimensions of writing, in the sense pointed out by Bakhtin in the early 1930s. Dialogism expands the notion of intertextuality to a social practice; enunciation appears polyphonic, and speakers are interacting. Every discourse is oriented to other discourses, interacting and responding to pre-existing discourses addressing the same object. Discourse is always others' discourse and shows a multiple and inter-relational subject.A fan producing meta-narratives or meta-discourses on media and fan fiction is an inter-relational subject. By way of illustration, Slaymesoftly, displays her stories on AO3, on her own Web site, and on specialized archives. She does not justify fan fiction writing through warnings or disclaimers but defines broadly what fiction is and how she uses fiction in her stories. She analyses publishing, describes her universe and the alternative universes that she explores, and depicts how stories become a series. Slaymesoftly can be considered a literate fan, approaching writing with emotion or attachment and critical rationality, or more precisely, leading her attachment to writing with the distance that critical thought allows. She writes "Essays -about writing, vampires, and whatever else I decide to blather on about" on her Web site or on her LiveJournal, where she also joined a community. In the main, Slaymesoftly experiences multiple variations, in the sense of Eco, variations that oppose and tie a character to a canon, or a loving writing object to what could be newly told. Slaymesoftly also exposes the desire for recognition engaged by fans' uses of interaction. This process of mutual recognition, stated in Hegel's Phenomenology of Spirit highlights and questions fans' attachment, individual identity, and normative foundation. Mutual recognition could strengthen communitarianism or conformism in writing, but it can also offer a way for attachments to be shared, a way to initiate a narrative, and a social practice of dialog.Dialogical dimensions of cultural practices of reading-writing (both in production and reception) design a fragmented narrative universe, unfinished but one, that can be comprehend in a socio-narrative device.Figure 2 (Masoni Lacroix & Cailler)Texts, authors, writers, and readers are not opposed but are part of a socio-narrative continuity. This device crosses three complementary and evolving dimensions of the narrative universe: techno-narrative, socio-narrative (playful, creative, and critical, in their interactivity), and narratological. Uses of literacy generating multimedia, cross-media, and transmedia productions also question the multimodal form of writing and invite us to an iterative, open, dialogical, and interrogative practice of multimodality. A (post)narratological activity opens up to an interrogative practice. This practice dialogs with others' discourse and narrative. The questioning complexity remains open. In a proximate meaning, a transmedia narrative is fragmented, open to incompletion, but enrolled in a continuum (Jenkins, "Transmedia").Looking back, through the overtaken dichotomy between production and reception, a social and narrative process has been described that leads to the reshaping of multiple uses of literacies into cultural practices, and further on, to a cultural and social practice of reading-writing blended into interactivity. Competencies, dictated uses of reading and writing and alterna(rra)tive upsurges (as fans' production content) can be questioned. What can be questioned is either the fragmentation, the incompletion, and the continuity of narratives, that Jenkins no longer brings into conflict ("Transmedia"). This is also what the social and narrative form of dialogism teaches us: dichotomies, as a tool or a structure of thought, appear suspect or no longer significant. There is continuity in the acculturation process, from acknowledgement to recognition, continuity in the multiple uses of interacting, continuity from narrative to discourse, continuity from emotion to writing critically, a transformative continuity in iteration and variation, a polyphonic continuity.ReferencesBakhtin, Michaïl, and V.N. Volosinov. Marxism and the Philosophy of Language. Cambridge: Harvard UP, 1973.Cailler, Bruno, and Céline Masoni Lacroix. "El 'French Touch' Transmediatico: Un Inventario." Transmediación: Espacios, Reflexiones y Experiencias. Eds. Denis Porto Renó et al. Bogotá, Colombia: Editorial Universidad del Rosario, 2012. 181-98.Davallon, Jean, and Joëlle Le Marec. "L'Usage en son Contexte. Sur les Usages des Interactifs des Céderons des Musées." Réseaux 101 (2000): 173-95.De Certeau, Michel. L'Invention du Quotidien. Paris: Folio Essais, 1990.Eco, Umberto. "Innovation and Repetition: Between Modern and Postmodern Aesthetics." Daedalus 114 (1985): 161-84.Hegel, G.W.F. Phénoménologie de l'Esprit. Trans. Bernard Bourgeois. Paris: Vrin, 2006.Jenkins, Henry. Convergence Culture. Where Old and New Media Collide. New York UP, 2006.———. "Transmedia 202: Further Reflections." 2011. <http://henryjenkins.org/2011/08/defining_transmedia_further_re.html>.Masoni Lacroix, Céline. "Mise en Récit des Fictions de Fans de Séries Télévisées: Variations, Granularité et Réflexivité." Tension narrative et Storytelling. Eds. Nicolas Pélissier and Marc Marti. Paris: L'harmattan, 2014. 83-100.———. "Narrativités 2.0: Fragmentation-Organisation d'un Métadiscours." Cahiers de Narratologie 32 (2017). <http://journals.openedition.org/narratologie/7781>.———, and Bruno Cailler. "Fans versus Universitaires, l'Hypothèse Dialogique de la Transmédialité au sein d'un Dispositif Socio-narratif." Revue française des sciences de l'information et de la communication 7 (2015). <http://journals.openedition.org/rfsic/1662>.———, and Bruno Cailler. "Principes Co-extensifs de la Fiction Sérielle, de la Distribution Diffusée à une Pratique Interprétative Dialogique: une Nouvelle Donne Socio-narrative?" Cahiers de Narratologie 31 (2016). <http://narratologie.revues.org/7576>. TV Show Fandoms ExploredBuffy The Vampire Slayer (Joss Whedon).Sherlock (Mark Gatiss & Steven Moffat).Twin Peaks (Mark Frost & David Lynch).Wallander (from Henning Mankell to Philip Martin).

Les interfaces mobiles actuelles permettent aux utilisateurs de manipuler directement les objets affichés à l’écran avec de simples gestes, par exemple cliquer sur des boutons ou des menus ou pincer pour zoomer. Pour accéder à un espace de commande plus large, les utilisateurs sont souvent forcés de passer par de nombreuses étapes, rendant l’interaction inefficace et laborieuse. Des gestes plus complexes sont un moyen puissant d’accéder rapidement à l’information ainsi que d’exécuter des commandes plus efficacement [5]. Ils sont en revanche plus difficiles à apprendre et à contrôler. Le “Gesture Typing” (saisie de texte par geste) est une alternative intéressante au texte tapé: il permet aux utilisateurs de dessiner un geste sur leur clavier virtuel pour entrer du texte, depuis la première jusqu’à la dernière lettre d’un mot. Dans cette thèse, j’augmente le pouvoir d’expression de l’interaction mobile en tirant profit de la forme et la dynamique du geste et de l’espace d'écran, pour invoquer des commandes ainsi que pour faciliter l’appropriation dans différents contextes d’usage. Je conçois "Expressive Keyboard", qui transforme la variation du geste en un résultat riche et je démontre plusieurs applications dans le contexte de la communication textuelle. Et plus, je propose "CommandBoard", un clavier gestuel qui permet aux utilisateurs de sélectionner efficacement des commandes parmi un vaste choix tout en supportant la transition entre les novices et les experts. Je démontre plusieurs applications de "CommandBoard", dont chacune offre aux utilisateurs un choix basé sur leurs compétences cognitives et moteur, ainsi que différentes tailles et organisations de l’ensemble des commandes. Ensemble, ces techniques donnent un plus grand pouvoir expressif aux utilisateurs en tirant profit de leur contrôle moteur et de leur capacité à apprendre, à contrôler et à s’approprier
Current mobile interfaces let users directly manipulate the objects displayed on the screen with simple stroke gestures, e.g. tap on soft buttons or menus or pinch to zoom. To access a larger command space, the users are often forced to go through long steps, making the interaction cumbersome and inefficient. More complex gestures offer a powerful way to access information quickly and to perform a command more efficiently [5]. However, they are more difficult to learn and control. Gesture typing [78] is an interesting alternative to input text: it lets users draw a gesture on soft keyboards to enter text, from the first until the final letter in a word. In this thesis, I increase the expressive power of mobile interaction by leveraging the gesture’s shape and dynamics and the screen space to produce rich output, to invoke commands, and to facilitate appropriation in different contexts of use. I design "Expressive Keyboard" that transforms the gesture variations into rich output, and demonstrate several applications in the context of textbased communication. As well, I propose "CommandBoard", a gesture keyboard that lets users efficiently select commands from a large command space while supporting the transition from novices to experts. I demonstrate different applications of "CommandBoard", each offers users a choice, based on their cognitive and motor skills, as well as the size and organization of the current command set. Altogether, these techniques give users more expressive power by leveraging human’s motor control and cognitive ability to learn, to control, and to appropriate

La tâche d'annotation, nécessaire à l'entraînement d'assistants conversationnels, fait habituellement appel à des experts du domaine à modéliser. Toutefois, l'annotation de données est connue pour être une tâche difficile en raison de sa complexité et sa subjectivité : elle nécessite par conséquent de solides compétences analytiques dans le but de modéliser les textes en intention de dialogue. De ce fait, la plupart des projets d'annotation choisissent de former les experts aux tâches d'analyse pour en faire des "super-experts". Dans cette thèse, nous avons plutôt décidé mettre l'accent sur les connaissances réelles des experts en proposant une nouvelle méthode d'annotation basée sur un Clustering Interactif. Celle-ci se base sur une coopération Homme/Machine, où la machine réalise un clustering pour proposer une base initiale d'apprentissage, et où l'expert annote des contraintes MUST-LINK ou CANNOT-LINK entre les données pour affiner itérativement la base d'apprentissage proposée. Une telle annotation présente l'avantage d'être plus instinctive, car les experts peuvent associer ou différencier les données en fonction de la similarité de leur cas d'usage, permettant ainsi de traiter les données comme ils le feraient professionnellement au quotidien. Au cours de nos études, nous avons pu montrer que cette méthode diminuait sensiblement la complexité de conception d'une base d'apprentissage, réduisant notamment la nécessité de formation des experts intervenant dans un projet d'annotation. Nous proposons une implémentation technique de cette méthode (algorithmes et interface graphique associée), ainsi qu'une étude des paramètres optimaux pour obtenir une base d'apprentissage cohérente en un minimum d'annotation. Nous réalisons également une étude de coûts (techniques et humains) permettant de confirmer que l'utilisation d'une telle méthode est réaliste dans un cadre industriel. De plus, afin que la méthode atteigne son plein potentiel, nous fournissons un ensemble de conseils, notamment : (1) des recommandations visant à cadrer la stratégie d'annotation, (2) une aide à l'identification et à la résolution des divergences d'opinion entre annotateurs, (3) des indicateurs de rentabilité pour chaque intervention de l'expert, et (4) des méthodes d'analyse de la pertinence de la base d'apprentissage en cours de construction. En conclusion, cette thèse offre une approche innovante pour concevoir une base d'apprentissage d'un assistant conversationnel, permettant d'impliquer les experts du domaine métier pour leurs vraies connaissances, tout en leur demandant un minimum de compétences analytiques et techniques. Ces travaux ouvrent ainsi la voie à des méthodes plus accessibles pour la construction de ces assistants
Usually, the task of annotation, used to train conversational assistants, relies on domain experts who understand the subject matter to model. However, data annotation is known to be a challenging task due to its complexity and subjectivity. Therefore, it requires strong analytical skills to model the text in dialogue intention. As a result, most annotation projects choose to train experts in analytical tasks to turn them into "super-experts". In this thesis, we decided instead to focus on the real knowledge of experts by proposing a new annotation method based on Interactive Clustering. This method involves a Human-Machine cooperation, where the machine performs clustering to provide an initial learning base, and the expert annotates MUST-LINK or CANNOT-LINK constraints between the data to iteratively refine the proposed learning base. Such annotation has the advantage of being more instinctive, as experts can associate or differentiate data according to the similarity of their use cases, allowing them to handle the data as they would professionally do on a daily basis. During our studies, we have been able to show that this method significantly reduces the complexity of designing a learning base, notably by reducing the need for training the experts involved in an annotation project. We provide a technical implementation of this method (algorithms and associated graphical interface), as well as a study of optimal parameters to achieve a coherent learning base with minimal annotation. We have also conducted a cost study (both technical and human) to confirm that the use of such a method is realistic in an industrial context. Finally, we provide a set of recommendations to help this method reach its full potential, including: (1) advice aimed at framing the annotation strategy, (2) assistance in identifying and resolving differences of opinion between annotators, (3) rentability indicators for each expert intervention, and (4) methods for analyzing the relevance of the learning base under construction. In conclusion, this thesis provides an innovative approach to design a learning base for a conversational assistant, involving domain experts for their actual knowledge, while requiring a minimum of analytical and technical skills. This work opens the way for more accessible methods for building such assistants

Abstract Grasses are the dominant plants of grasslands (Chapter 1) and of agriculture. The systematics and evolution of this large, diverse, and phylogenetically advanced family are described in this chapter. Agrostology is the science of grass classification, and, as noted by Gould (1955), is essential to the study of grassland. However, the taxonomic treatment of the grasses has a fascinating history in itself as investigators moved from the use of primary morphological and anatomical characters to include cytogenetic, physiological, and molecular characters allowing the development of increasingly evolutionarily informative classifications (Stebbins 1956). The evolution of this family, although still incompletely understood, represents an interesting example of adaptation and co-evolution with environmental and biotic factors, especially aridity and grazing.