Relevant bibliographies by topics / CNS condition

Academic literature on the topic 'CNS condition'

Author: Grafiati
Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "CNS condition"

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Silver, Jerry. "CNS Regeneration: Only on One Condition." Current Biology 19, no. 11 (June 2009): R444—R446. http://dx.doi.org/10.1016/j.cub.2009.04.026.

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Han, Guansheng, Fei Xiong, Yu Zhou, Leibo Song, and Xingkai Wang. "Research Progress on Shear Characteristics of Rock Joints under Constant Normal Stiffness Boundary Conditions." Shock and Vibration 2021 (September 1, 2021): 1–6. http://dx.doi.org/10.1155/2021/9670151.

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The constant normal stiffness (CNS) boundary condition is more representative for the underground engineering, in which the shear-induced dilation is restricted by surrounding rocks, resulting in an increase in the normal stress. Therefore, the use of CNS boundary conditions in the research of shear-slip failure of underground rock engineering is more in line with the actual situation. Taking the instability and failure of surrounding rock in underground engineering as the background, the present study introduces the engineering background of CNS boundary conditions and the research progress on shear characteristics of rock joints under CNS boundary conditions. Three key directions for future research are proposed based on the latest research results of shear characteristics of rock joint under CNS boundary conditions: ① developing a rock joint shear test system that can realize the function of “CNS boundary conditions + shear-seepage test + visualization”; ② carrying out the shear tests of real rock joints under CNS boundary conditions based on 3D scanning and 3D carving technology; and ③ carrying out the shear tests of rock joint network under CNS boundary conditions.
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Cao, Yangbing, Yang Wu, Xiangxiang Zhang, Zhi Liu, Weiguo Gong, and Zhenping Huang. "Experimental Study on the Influence of Hydromechanical Boundary Conditions on Shear-Flow Coupling Characteristics of Granite Joints." Geofluids 2022 (August 22, 2022): 1–17. http://dx.doi.org/10.1155/2022/4030000.

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The instability of jointed rock mass is usually the shear process of the rock mass along discontinuities under the influence of groundwater flow. By conducting laboratory tests and numerical experiments on the shear-flow coupling of rock joints under constant normal stiffness (CNS) and constant normal stress (CNL) boundary conditions, the influence of normal boundary conditions and seepage pressure on the shear mechanical and flow characteristics of joints were investigated. The test results were as follows: The joint shear stiffness, peak, and residual shear strength under the CNS boundary condition were predominantly larger than those under the CNL boundary condition. Overall, these parameters were positively correlated with the initial normal stress σ n 0 . When σ n 0 > 2 MPa, the postpeak shear stress of the CNS boundary condition showed a sharp decrease, whereas that of the CNL boundary condition changed from a slowly decreasing type ( σ n 0 = 4 MPa, 6 MPa) to a sharply decreasing type at σ n 0 = 8 MPa. The peak dilation rate under the CNS boundary condition at all levels of normal stress was lower than that of CNL, and the strain softening in postpeak of the latter was more remarkable. In the process of joint shear, the hydraulic aperture displayed a four-stage variation law of “steady-sudden increase-slow increase-basically stable.” Moreover, the hydraulic aperture under the CNS boundary condition was always lower than that under the CNL boundary condition. The seepage pressure increased from 0.5 MPa to 1.5 MPa, and the average hydraulic aperture in the stable stage under normal stress at all levels increased from 0.146 mm to 0.187 mm. In addition, the average peak shear stress and average shear stiffness decreased by 0.9 MPa and 0.83 GPa/m, respectively. We also established a numerical model of a real rough three-dimensional joint, compiled a calculation program for the shear-flow process of a joint under CNS boundary conditions, and visualized the flow channel inside the joint. The seepage flow bypassed the area where the joints contacted each other, forming obvious flow channels. The flow rate increased at the intersection of the flow channels.
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Sanei Taheri, Morteza, Mohammad Ali Karimi, Hamidreza Haghighatkhah, Ramin Pourghorban, Mohammad Samadian, and Hosein Delavar Kasmaei. "Central Nervous System Tuberculosis: An Imaging-Focused Review of a Reemerging Disease." Radiology Research and Practice 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/202806.

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Central nervous system (CNS) tuberculosis is a potentially life threatening condition which is curable if the correct diagnosis is made in the early stages. Its clinical and radiologic manifestations may mimic other infectious and noninfectious neurological conditions. Hence, familiarity with the imaging presentations of various forms of CNS tuberculosis is essential in timely diagnosis, and thereby reducing the morbidity and mortality of this disease. In this review, we describe the imaging characteristics of the different forms of CNS tuberculosis, including meningitis, tuberculoma, miliary tuberculosis, abscess, cerebritis, and encephalopathy.
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Kanaev, A. K., E. V. Oparin, and E. V. Oparina. "Entropic model of network dynamics of clocking network synchronization." Journal of Physics: Conference Series 2131, no. 4 (December 1, 2021): 042089. http://dx.doi.org/10.1088/1742-6596/2131/4/042089.

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Abstract The main task of the clocking network synchronization (CNS) network subsystem is the formation, transmission, distribution and delivery of synchronization signals to the telecommunication system (TCS) digital equipment for the purpose of its coordinated interaction. Indicators of the telecommunication services quality are inextricably linked with the indicators of the CNS network functioning quality, in this regard, the process of monitoring and managing the CNS network comes to the fore for the purpose of prompt detection of failures and their subsequent elimination. The article provides an overview of the main classes of CNS network equipment and their diagnostic parameters, and also indicates the significant influence of the CNS network functioning process on the entire TCS functioning. To assess the technical condition of the CNS network an approach using the entropy analysis of the diagnostic parameters of the CNS network elements is proposed. The entropy model of the network dynamics is obtained in CNS work, which can later be used to develop a methodology for monitoring the technical condition of the CNS network. Using this model, it is possible to estimate not only the differential entropy of each CNS network element, but also to estimate the differential entropy of the entire CNS network or a separate fragment of the CNS network. Differential entropy parameters reflect the technical state of the CNS network.
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GUPTA, MOHIT, RAVI SHEKHAR, and JAGDISH K. SAHU. "ROLE OF DRUG DISCOVERY IN CENTRAL NERVOUS SYSTEM DISORDERS: AN OVERVIEW." Current Research in Pharmaceutical Sciences 11, no. 3 (October 8, 2021): 86–90. http://dx.doi.org/10.24092/crps.2021.110302.

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Central nervous system (CNS) stimulants are drugs, which produce a response that could be used to alleviate a particular medical condition. These are the agents, which speed up to treat conditions characterized by lack of adrenergic stimulation, including narcolepsy and neonatal apnea. The majority of CNS stimulants is chemically similar to the neurohormone norepinephrine and simulates the traditional "fight or flight" syndrome associated with sympathetic nervous system arousal. A small figure of added members of the CNS stimulant class do not fall into definite chemical groups. The review on central nervous system stimulants gives detail study of CNS stimulant drugs, their mechanism of action and in vivo models of CNS stimulants. The brain is a delicate tissue, and advancement built very effective methods to guard it. Unfortunately, the same mechanisms that protect it against intrusive chemicals can also upset therapeutic interventions. Many current medications are rendered unsuccessful in the treatment of cerebral maladies due to our incapability to efficiently deliver and sustain them within the brain. KEYWORDS: CNS Stimulants, Blood brain barrier (BBB), Drug toxicity, Drug Safety
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Wang, Xiangyu, Ruofan Wang, and Zizheng Zhang. "Numerical Analysis Method of Shear Properties of Infilled Joints under Constant Normal Stiffness Condition." Advances in Civil Engineering 2018 (August 1, 2018): 1–13. http://dx.doi.org/10.1155/2018/1642146.

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The direct shear test is implemented in this paper for infilled joints under constant normal stiffness (CNS) condition with the finite difference software FLAC3D. The CNS condition was performed based on a servoprogram developed by FISH language. The effects of initial normal stress, undulating angle, and infilled ratio on the shear failure mode of infilled joints under CNS are revealed based on numerical simulation. It is found that the shear strength of infilled joints will grow along with the increase of the undulating angle and the decrease of the infilled ratio. The numerical analysis method is also able to quantify the effect of multiple factors (initial normal stress and infilled ratio) on shear properties of infilled joints. The model shows a good agreement with the experimental results available in the literatures. Therefore, this study proposed and verified a numerical analysis method capable of studying the effects of normal stress, undulating angles, and infilled ratio on the shear behavior of infilled rock joints.
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Behl, Ajay, Lorie Ellis, Dominic Pilon, Patrick Lefebvre, and Nancy Ann Dawson. "Observation of CNS events in real-world use of enzalutamide (ENZ) and bicalutamide (BIC)." Journal of Clinical Oncology 34, no. 2_suppl (January 10, 2016): 235. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.235.

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235 Background: TERRAIN, a randomized, double-blind, multi-center, phase II trial compared efficacy and safety of ENZ to BIC in men with mCRPC. Although ENZ and BIC fall within the same drug classification, rates of seizure and other central nervous system (CNS) events, observed in non-clinical trial populations have not been explored. The objective of this study was to compare rates of real world CNS events in patients treated with ENZ or BIC. Methods: Retrospective claims from Truven Health MarketScan database were used to identify patients with a PC diagnosis; ≥1 claim for ENZ or BIC (index date) after 9/1/2012; > 6 months of continuous eligibility prior to index date (baseline period) and no use of ENZ or BIC prior to index. Patients were followed until 12/2014 or loss to follow-up. Patients were excluded if they had a CNS condition or another cancer diagnosis during the baseline period. CNS conditions were defined as a diagnosis for amnesia or memory impairment, anxiety, ataxia, cognitive disorders, confusion, convulsions, disturbance in attention, dizziness, falls, fatigue/asthenia, hallucinations, headaches, insomnia, pain, paresthesia, seizures, weakness, or other CNS disorders. Kaplan-Meier (KM) survival curves were used to compare the KM rates of developing any CNS conditions between patients who initiated ENZ relative to patients who initiated BIC. A subgroup analysis of patients with metastatic disease was performed. Results: The table below compares the development of CNS conditions between ENZ and BIC patients. Conclusions: This study shows that rates of CNS events are significantly higher in patients initiating ENZ as compared to BIC, even when controlling for metastatic status. [Table: see text]
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Busechian, Sara, Luca Turini, Micaela Sgorbini, Camillo Pieramati, Lorenzo Pisello, Simona Orvieto, and Fabrizio Rueca. "Are Horse Owners Able to Estimate Their Animals’ Body Condition Score and Cresty Neck Score?" Veterinary Sciences 9, no. 10 (October 3, 2022): 544. http://dx.doi.org/10.3390/vetsci9100544.

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Obesity and overconditioning are becoming more prevalent in horses, and are influencing the animal’s health, activity, and reproductive efficiency. Body condition score (BCS) and cresty neck score (CNS) have been correlated with the development of various diseases. Many of the papers in the literature evaluate the prevalence of obesity and overconditioning in horse populations considering BCS given by owners. The aim of this study was to evaluate the validity of the owners’ estimation of the degree of equine obesity or overconditioning by comparing BCS and CNS provided by each owner and a board-certified vet to a cohort of 259 horses and their agreement based on age, breed, sex, and activity of the animals. Overconditioning was present in 29% and 24% of horses according to the owners and the vet, respectively, and obesity in 2% and 1%, respectively. Agreement between BCS and CNS given by the owners and the vet was slight, with owners scoring horses either lower or higher than the vet. Agreement between the owners and the vet assessment was also influenced by age, breed, sex, and activity of the animals. Education of owners and caretakers to correctly assess BCS and CNS and regular evaluation of the animals throughout the year is important to prevent the development of obesity and overconditioning and related diseases.
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Weiner, Debra K., Angela Gentili, Katherine Coffey-Vega, Natalia Morone, Michelle Rossi, and Subashan Perera. "Biopsychosocial Profiles and Functional Correlates in Older Adults with Chronic Low Back Pain: A Preliminary Study." Pain Medicine 20, no. 7 (April 16, 2018): 1300–1310. http://dx.doi.org/10.1093/pm/pny065.

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Abstract Objective To describe key peripheral and central nervous system (CNS) conditions in a group of older adults with chronic low back pain (CLBP) and their association with pain severity and self-reported and performance-based physical function. Design Cross-sectional. Setting Outpatient VA clinics. Subjects Forty-seven community-dwelling veterans with CLBP (age 68.0 ± 6.5 years, range = 60–88 years, 12.8% female, 66% white) participated. Methods Data were collected on peripheral pain generators—body mass index, American College of Rheumatology hip osteoarthritis criteria, neurogenic claudication (i.e., spinal stenosis), sacroiliac joint (SIJ) pain, myofascial pain, leg length discrepancy (LLD), and iliotibial band pain; and CNS pain generators—anxiety (GAD-7), depression (PHQ-9), insomnia (Insomnia Severity Index), maladaptive coping (Fear Avoidance Beliefs Questionnaire, Cognitive Strategies Questionnaire), and fibromyalgia (fibromyalgia survey). Outcomes were pain severity (0 to 10 scale, seven-day average and worst), self-reported pain interference (Roland Morris [RM] questionnaire), and gait speed. Results Approximately 96% had at least one peripheral CLBP contributor, 83% had at least one CNS contributor, and 80.9% had both peripheral and CNS contributors. Of the peripheral conditions, only SIJ pain and LLD were associated with outcomes. All of the CNS conditions and SIJ pain were related to RM score. Only depression/anxiety and LLD were associated with gait speed. Conclusions In this sample of older veterans, CLBP was a multifaceted condition. Both CNS and peripheral conditions were associated with self-reported and performance-based function. Additional investigation is required to determine the impact of treating these conditions on patient outcomes and health care utilization.
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Dissertations / Theses on the topic "CNS condition"

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Aguilar, Salegio Ernest Antonio, and Ernest Aguilar@flinders edu au. "Pre-Conditioned Lesion: Inflammatory Effects on CNS Regeneration." Flinders University. School of Medicine, 2009. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20100621.024316.

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In the adult central nervous system (CNS) several factors are implicated in the failure of neurons to regenerate after spinal cord injury (SCI). However, this reduced ability of injured CNS neurons to regenerate can be improved by under certain conditions. For instance, in adult dorsal root ganglion (DRG) neurons, injury to its peripheral branch (unilateral conditioning lesion) prior to injury of its central DRG branch (dorsal column cut) enhances the intrinsic capability of some but not all CNS afferent neurons to regenerate. The exact mechanism mediating this type of response is not known. However, previous studies by other groups have proposed that the regeneration of these CNS afferent neurons might be associated with the inflammatory response following injury to the peripheral DRG branch. Our general aim, was to examine the involvement of the immune response in the regeneration of the CNS DRG branch, as part of the pre-conditioned lesion model. To test this, three questions/hypotheses were investigated. Firstly, we investigated the effects of vaccination in pre-conditioned lesion animals using a peripheral nerve homogenate (PNH, sciatic nerve) as the immunogen. Given the regenerative capabilities of peripheral nerves, we proposed that exposure to this homogenate could enhance the limited regeneration of CNS fibres, after pre-conditioning of DRG neurons. Our results showed that in adult and/or neonatal Sprague Dawley (SD) rats PNH-vaccinated, had greater number of regenerated fibres, as compared to injury matched saline-vaccinated controls. Conversely, passive exposure to PNH through parental vaccination resulted in the suppression of this regenerative trigger. This suppressed competence of CNS fibres to regenerate was indirectly correlated with a reduced number of macrophage cells throughout the SCI epicentre, as compared to greater macrophage numbers found in the adult and/or neonatal treated groups. Secondly, we explored the possibility that a systemic inflammatory effect originating from the peripheral conditioning lesion, might be able to contribute to the regeneration of other injured neurons within the matured CNS. Again, using adult SD rats, we pre-conditioned the peripheral DRG branch as previous and changed the location of the CNS injury from the spinal cord to the optic nerve. Where alike any other injured neuron within the CNS, fails to regenerate. Unfortunately, our results from anterograde or retrograde labelling did not find any regenerated optic nerve fibres, although, we did find macrophage numbers to be higher in pre-conditioned lesion animals as compared to sham-operated animals. Therefore, it is possible that the pre-conditioning peripheral lesion might be allowing for a greater macrophage infiltration into the CNS compartment. Finally, we determined whether an early macrophage infiltration into the CNS compartment could be correlated with the observed CNS regeneration, characteristic of the pre-conditioned lesion model. To test this, we temporarily depleted macrophages before, during and after peripheral nerve lesion, via liposomal clodronate delivery. Our results from anterograde and retrograde labelling of spinal cord fibres revealed no regenerated CNS fibres in macrophage depleted animals, only in injury matched controls. In conclusion, macrophage cells play a beneficial role in the regeneration of CNS afferent fibres of pre-conditioned lesion DRG neurons. This most likely occurs through activation of intrinsic somatic DRG responses, as well as, an increased macrophage activation. We believe this inflammatory response to be of favourable phenotypic characteristic to the regeneration of injured CNS neurons, especially those in proximity to the DRG cell body. In addition, we propose that the conditioning peripheral lesion permits an influx of macrophage cells into the CNS compartment before injury of the CNS DRG branch, which is also likely to be supporting regeneration of afferent fibres. Future studies should evaluate the possibility that activated inflammatory cells might be infiltrating into the CNS under minimal blood-brain barrier disruption. It is clear that a complex communication between the nervous and immune system is occurring after the initial peripheral injury.
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Suidan, Georgette Leila. "CD8 T cells mediate CNS vascular permeability under neuroinflammatory conditions." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1242912012.

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Hede, Brian P. "Condition monitoring of tools in CNC turning." Thesis, Loughborough University, 2008. https://dspace.lboro.ac.uk/2134/14320.

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The metal cutting industry today is highly automated and, as a step towards Europe's ability to compete on the world market, an increased level of automation can be expected in the future. Therefore, much attention has been paid to the use of automated monitoring systems within the maintenance strategies designed to prevent breakdown. This research focuses on the condition monitoring of cutting tools in CNC turning, using airborne acoustic emission, (AAE). A structured approach for overcoming the problems associated with changing cutting parameters is presented with good results. A reverse and novel approach in estimating gradual tool wear in longitudinal roughing has been made by predicting cutting parameters directly from the acoustics emitted from the process. Using the RMS as a representation of the energy in the signal, where the spectral distributions are working as divisional operators, it has been possible to accurately extract a representation of feed rate, depth of cut and cutting speed from the signal. Using a simplified relationship to estimate tangential cutting force, a virtual force can be calculated and related to a certain amount of flank wear using non-linear regression. Furthermore, this research presents a monitoring solution where disturbances are eliminated by recognising the sound signatures where it, afterwards, is possible to evaluate the reliability of the wear decision. This is done by describing irregularities in the signal , where surface parameters used on a sound waveform, combined in a neural network, has been used to trigger outputs for several defined classes of disturbances. An investigation of the two wear types flank and crater wear, has been conducted and is has been concluded, that although crater wear has an effect on the AAE, it is difficult to recognise this. AAE has shown to an efficient tool to detect flank wear, where a direct relationship is shown between the changes in the cutting parameters, tool wear and AAE. This approach has resulted in a precise monitoring so lution, where flank wear can be estimated within an error of I0%.
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Yu, Adam Christopher. "Neuroinflammatory conditions modulate ARNT2 and RME-8 expression within the CNS." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/58643.

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Microglia are the primary immune cells found within the central nervous system (CNS), playing a vital role in neuronal function, trophic support and also modulating immune or inflammatory responses to pathogens or damage during disease. Microglia are essential to repair processes influencing axonal health and remyelination. However, the study of microglia is limited as significant yields of microglia through tissue culture are difficult to obtain. We show that the addition of granulocyte macrophage colony-stimulating factor (GM-CSF) during the culture of embryonic microglia yields significantly greater cell numbers. GM-CSF cultured microglia exhibit a non-differentiated phenotype similar to in vivo microglia and represent a useful model for disease and reparative processes in the CNS. Using our primary microglial model, we investigated two proteins, Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2) and receptor-mediated endocytosis – 8 (RME-8). ARNT2, a transcription factor for several proteins but most notably for the neuronal growth factor, brain derived neurotrophic factor (BDNF), has been primarily studied in neurons. Our studies show regulation of ARNT2 in astrocytes and immune cells (microglia and splenocytes) under inflammatory conditions. In the experimental autoimmune encephalomyelitis (EAE) model, splenocytes exhibited lower ARNT2 expression than those from healthy controls. Lipopolysaccharide and interferon-γ increased otherwise low ARNT2 expression in microglia. RME-8 is a protein that is important in endosomal trafficking. Mutations in RME-8 have been linked to Parkinson’s disease and essential tremor. However, RME-8 has yet to be characterized within the CNS. Motor neurons, astrocytes and ependymal cells expressed RME-8 in healthy control mice; RME-8 was increased and co-localized with CD68 positive cells in immune infiltrates in EAE mice. Our results show the uptake of dextran in RME-8 mutant knock-in microglia is decreased, indicating the importance of this protein in phagocytic processes. These results show that microglia can be effectively cultured from embryonic tissue with the addition of GM-CSF in comparison to previously established protocols and are similar to microglia in vivo. Furthermore, inflammatory mediators influence expression of ARNT2 and RME-8 and may highlight roles for each in neuroprotection or phagocytic function respectively, thereby influencing inflammatory neurodegenerative or reparative processes relevant to several diseases in the CNS.
Medicine, Faculty of
Pathology and Laboratory Medicine, Department of
Graduate
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Hoh, See Min. "Condition monitoring and fault diagnosis for CNC machine tools." Thesis, Cardiff University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295120.

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Harris, C. G. "Fault diagnosis and condition monitoring for NC/CNC machine tools." Thesis, Cardiff University, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381227.

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Ajilo, Deborah (Deborah M. ). "eyeDNA : Tool Condition Monitoring for a desktop CNC milling machine." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/115670.

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Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2018.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 81-84).
Tool wear is a major obstacle to realizing full automation in metal cutting operations. In this thesis, we designed and implemented a low cost Tool Condition Monitoring (TCM) system using off-the-shelf sensors and data acquisition methods . Peripheral end milling tests were done on a low carbon steel workpiece and the spindle vibration, cutting zone temperature and spindle motor current were recorded. Features from these data sources were used to train decision tree models in MATLAB with the aim of classifying the stages of tool wear. Results showed that the feature sets fusing information from all data sources performed the best, classifying the tool wear stage with up to 93% average accuracy.
by Deborah Ajilo.
S.M.
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Sztendel, Sebastian. "Model referenced condition monitoring of high performance CNC machine tools." Thesis, University of Huddersfield, 2016. http://eprints.hud.ac.uk/id/eprint/34112/.

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Generally, machine tool monitoring is the prediction of the system’s health based on signal acquisition and processing and classification in order to identify the causes of the problem. The producers of machine tools need to pay more attention to their products life cycle because their customers increasingly focus on machine tool reliability and costs. The present study is concerned with the development of a condition monitoring system for high speed Computer Numerical Control (CNC) milling machine tools. A model is a simplification of a real machine to visualize the dynamics of a mechatronic system. This thesis applies recent modelling techniques to represent all parameters which affect the accuracy of a component produced automatically. The control can achieve an accuracy approaching the tolerance restrictions imposed by the machine tool axis repeatability and its operating environment. The motion control system of the CNC machine tool is described and the elements, which compose the axis drives including both the electrical components and the mechanical ones, are analysed and modelled. SIMULINK models have been developed to represent the majority of the dynamic behaviour of the feed drives from the actual CNC machine tool. Various values for the position controller and the load torque have been applied to the motor to show their behaviour. Development of a mechatronic hybrid model for five-axis CNC machine tool using Multi-Body-System (MBS) simulation approach is described. Analysis of CNC machine tool performance under non-cutting conditions is developed. ServoTrace data have been used to validate the Multi-body simulation of tool-to-workpiece position. This thesis aspects the application of state of art sensing methods in the field of condition monitoring of electromechanical systems. The ballscrew-with-nut is perhaps the most prevalent CNC machine subsystem and the condition of each element is crucial to the success of a machining operation. It’s essential to know of the health status of ballscrew, bearings and nut. Acoustic emission analysis of machines has been carried out to determine the deterioration of the ballscrew. Standard practices such as use of a Laser Interferometer have been used to determine the position of the machine tool. A novel machine feed drive condition monitoring system using acoustic emission (AE) signals has been proposed. The AE monitoring techniques investigated can be categorised into traditional AE parameters of energy, event duration and peak amplitude. These events are selected and normalised to estimate remaining life of the machine. This method is shown to be successfully applied for the ballscrew subsystem of an industrial high-speed milling machine. Finally, the successful outcome of the project will contribute to machine tool industry making possible manufacturing of more accurate products with lower costs in shorter time.
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Sebnem, Cansun. "Démocratisation, égalité des sexes et implication des femmes en politique : le cas de deux partis politiques turcs, l'AKP et le CHP." Grenoble, 2010. http://www.theses.fr/2010GRENH025.

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En Turquie, la problématique de l'égalité des sexes et la féminisation de la politique ont pris une importance croissante dans la démocratisation du pays. Cette thèse examine comment deux partis politiques issus d'idéologies différentes accueillent la norme d'égalité des sexes et les femmes en politique. Les partis étudiés sont Adalet ve Kalkınma Partisi (l'AKP, le Parti de la justice et du développement), de centre droit et Cumhuriyet Halk Partisi (le CHP, le Parti républicain du peuple), de centre gauche. Notre recherche, qui se fonde sur deux quotidiens d'idéologie différente, Yeni Şafak (La nouvelle aurore) et Cumhuriyet (La république), les publications internes des partis politiques, les programmes, leurs statuts et une cinquantaine d'entretiens, montre que les deux partis traitent tous les deux de la cause des femmes. Les dirigeants de l'AKP considèrent les problèmes des femmes comme un domaine où ils peuvent manifester une rupture avec leur passé islamiste. Etant au pouvoir, l'AKP fait de grands efforts pour la cause des femmes. Pourtant à l'AKP, il y a des adhérents qui n’ont pas intériorisé l'idée de l'égalité des sexes, le discours conserve certains aspects très conservateurs, et le parti s'oppose aux quotas dans ses statuts. Au CHP, l'égalité des sexes est ancrée dans la culture du parti, renforcée par un quota de genre inscrit dans les statuts. Mais les femmes promues en politique ne sont pas aussi nombreuses qu'on pourrait l’attendre. Cette recherche montre que malgré leurs différences d'idéologie, en Turquie, le centre gauche et droit ne sont pas très différents l'un de l'autre en ce qui concerne la pratique de l'approche des problèmes des femmes et la promotion des femmes en politique
In Turkey, the problematic of gender equality and the feminisation of the governing bodies have drawn more attention than ever in the context of democratisation. This thesis aims at assessing to what extent two ideologically different political parties differ from each another in their outlook on gender politics and women politicians. The two leading parties of the country, Adalet ve Kalkınma Partisi (the JDP, the Justice and Development Party) of the center right and Cumhuriyet Halk Partisi (The RPP, the Republican People’s Party) of the center left form our research cases. The analysis is based on two ideologically different dailies, Yeni Şafak (The New Dawn) and Cumhuriyet (The Republic), on party publications, programs, and statutes and on about fifty interviews. The conclusion shows that both the JDP and the RPP defend women’s cause. The JDP leaders take women’s problems as a domain where they can prove that they have departed their Islamist background. Being in office, the JDP makes a great effort in favor of women’s cause. However, in the JDP, there are members who have not yet internalized gender equality. The party’s discourse contains very conservative statements, and the JDP strongly opposes gender quotas. In the RPP, gender equality is imprinted in the party’s political culture, and reinforced by the endorsement of a gender quota in its statutes. However, women politicians are not as frequently promoted as we would anticipate. This research shows that, despite some evidence of ideological differences, in Turkey, the center left and right are not very different one from another in the implementation of their approach to women’s problems and to the promotion of women as politicians
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LAHNAOUI, FATIMA. "Eléments de géographie sociale : cas de Safi - Maroc." Paris 13, 1996. http://www.theses.fr/1996PA131021.

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Dans le cadre de notre etude sous l'intitulee elements de geographie sociale du maroc avec pour exemple la ville de safi, nous avons essaye de trouver une explication a trois questions. Les deux premieres constituent une preoccupation pour toute la population et la troisieme releve de nos efforts intellectuels et notre enquete sur le terrain. - comment explique t-on le fait que la majorite de la population safiote vit dans des conditions extremes de pauvrete qui se repercutent sur leurs logements et leur condition de vie alors que la ville est connue dans le monde entier par ses activites industrielles et portuaires? - comment se fait-il qu'il y ait seulement une minorite de la population qui jouisse de conditions de vie confortables? - est-il normal que le niveau de vie des pauvres ne se soit pas ameliorer apres l'independance malgre les efforts entrepris dans le domaine de creation d'emplois et d'amenagement du territoire? notre etude nous permet d'affirmer que ces problemes auxquels est confronte notre societe sont dus a la presence dans l'espace d'un systeme economique moderne qui n'a pas essaye d'integrer l'ancien. Ce qui a cree un dualisme au sein de la societe. Ce dualisme se traduit par la presence d'une population minoritaire beneficiant de revenus tres eleves et d'une autre majoritaire n'ayant que des gains symboliques. Au niveau social, la situation evoquee s'explique par la presence d'une classe riche, certes, mais minoritaire qui reduit le pouvoir des pauvres. Apres l'independance des efforts entrepris ont certes abouti a des changements mais ils ont suivi le meme schema classique (celui herite de la periode coloniale).
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Books on the topic "CNS condition"

1

Crushell, James M. Condition monitoring support tools for CNC machines. Dublin: University College Dublin, 1995.

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Nihon Yushutsunyū Ginkō. Kaigai Tōshi Kenkyūjo. Tenkanki Roshia, CIS keizai no genjitsu: CIS Kenkyūkai hōkokusho. Tōkyō: Nihon Yushutsunyū Ginkō Kaigai Tōshi Kenkyūjo, 1994.

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Alain, Turnier, ed. Haïti, un cas. [Port-au-Prince?: s.n., 1985.

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Patrick, Heenan, and Lamontagne Monique, eds. The CIS handbook. London: Fitzroy Dearborn, 1999.

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Mariko, N'Tji Idriss. Développement et culture: Le cas du Mali. Bamako: Centre Djoliba, 1988.

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Kaser, Michael Charles. Privatization in the CIS. London: Russian and CIS Programme, Royal Institute of International Affairs, 1995.

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Ces goulots qui étranglent le Sénégal. Paris: L'Harmattan, 2014.

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Marosvári, Mária. Conditions et limites de la traduction littéraire: Le cas de L'assommoir d'Émile Zola. [Debrecen]: KLTE Francia Tanszék, 1990.

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Cormier, Linda. La condition féminine en milieu ouvrier, 1900-1950: Témoignages de trois montréalaises. [s.l.]: Cormier, 1990.

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Coulibaly, Nguessé Joachim Bangassaro. Le mal ivoirien: Cas symptomatique du mal africain. Paris: L'Harmattan, 2009.

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Book chapters on the topic "CNS condition"

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Xia, Caichu, Qiangfeng Yu, Yang Gui, Xin Qian, Xiaoqing Zhuang, and Songbo Yu. "Shear Behavior of Rock Joints Under CNS Boundary Condition." In Proceedings of GeoShanghai 2018 International Conference: Rock Mechanics and Rock Engineering, 263–74. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-0113-1_29.

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Donati, Davide Maria, and Giuseppe Bianchi. "Chondrosarcomas (CHS)." In Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions, 157–79. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-29676-6_34.

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Camilleri, Juanito. "A conditional operator for CCS." In Lecture Notes in Computer Science, 142–56. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/3-540-54430-5_86.

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Bussmann, Kai-D., Sebastian Oelrich, Andreas Schroth, and Nicole Selzer. "Cultural and Structural Conditions of Corruption." In The Impact of Corporate Culture and CMS, 9–29. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-72151-0_2.

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Leung, Joseph Wai-Hin, Way Kwok-Wai Lau, Benson W.-M. Lau, and Benjamin K. Yee. "A Commentary on the Therapeutic Potential of Melatonin and Its Analogues in CNS Conditions." In Psychiatry and Neuroscience Update, 177–86. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-95360-1_15.

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Indraratna, Buddhima, and Asadul Haque. "Highlights of rock joint behaviour under CNL and CNS conditions, and recommendations for the future." In Shear Behaviour of Rock Joints, 149–54. London: CRC Press, 2021. http://dx.doi.org/10.1201/9781003211297-6.

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Mastromarco, Camilla, Pierluigi Toma, and Cinzia Daraio. "Teaching Efficiency of Italian Universities: A Conditional Frontier Analysis." In Teaching, Research and Academic Careers, 319–58. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-07438-7_11.

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AbstractThe aim of this chapter is to provide a comparative analysis of the performance of teaching at Italian university by evaluating the efficiency of heterogeneous faculty courses at the national level. For this purpose, we use advanced and robust nonparametric tools recently developed in nonparametric efficiency frontier literature. This performance assessment does not rely on hypotheses about the relationship between inputs and outputs and allows us to account for the heterogeneity of the analyzed courses. The overall analysis carried out at the national level for Italy extends the traditional and limited one-dimensional indicators available through SUA-CdS data and ad hoc surveys on graduates conducted by ANVUR (National Agency for the Evaluation of Universities and Research Institutes) and MIUR (Ministry of Education, University and Research). The estimated efficiency scores are used to analyze current trends and changes in the teaching activities of Italian universities.
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Li, Liu, Matthew Sinclair, Antonios Makropoulos, Joseph V. Hajnal, A. David Edwards, Bernhard Kainz, Daniel Rueckert, and Amir Alansary. "CAS-Net: Conditional Atlas Generation and Brain Segmentation for Fetal MRI." In Uncertainty for Safe Utilization of Machine Learning in Medical Imaging, and Perinatal Imaging, Placental and Preterm Image Analysis, 221–30. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-87735-4_21.

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Ning, Qian, Taiyong Wang, Lu Liu, and Yongxiang Jiang. "Research on CNC Machine Tools Integration Condition Monitoring System and Its Information Exchange Technology." In Future Computing, Communication, Control and Management, 441–50. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-27326-1_57.

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Ryan, Matthew J., Gerard Verkleij, and Vincent Robert. "Data resources: role and services of culture collections." In Trends in the systematics of bacteria and fungi, 83–92. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789244984.0083.

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Abstract Microbial culture collections (CC) support taxonomy through the provision and preservation of microorganisms, underpinning the integrity of research. However, cultures are essentially worthless without associated data. Details of isolation (geographical location, date of collection, date of isolation), preservation, identification, characterization, growth conditions, properties and applications, etc., make up the key microbial data set that should be associated with every culture. This chapter summarizes the current status of data curation in fungal CCs, assess the challenges of maintaining genomic and bioinformatic data and investigate how collections need to evolve to meet the challenges of data acquisition and maintenance in the future in order to underpin taxonomy.
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Conference papers on the topic "CNS condition"

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Yu, Qingfeng, and Quanke Feng. "Safety Design and Mock-Up Tests on the Combustion of Hydrogen-Air Mixture in the Vertical CNS Channel of the CARR-CNS." In 14th International Conference on Nuclear Engineering. ASMEDC, 2006. http://dx.doi.org/10.1115/icone14-89815.

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A two-phase thermo-siphon loop is applied to the Cold Neutron Source (CNS) of China Advanced Research Reactor (CARR). The moderator is liquid hydrogen. The two-phase thermo-siphon consists of the crescent-shape moderator cell, the moderator transfer tube, and the condenser. The hydrogen is supplied from the buffer tank to the condenser. The most characteristic point is that the cold helium gas is introduced into the helium sub-cooling system covering the moderator cell and then flows up through the tube covering the moderator transfer tube into the condenser. The helium sub-cooling system also reduces the void fraction of the liquid hydrogen and takes a role of the helium barrier for preventing air from intruding into the hydrogen system. We call the two-phase thermo-siphon the hydrogen cold system. The main part of this system is installed in the CNS channel made of 6061 aluminum alloy (6061A) of 6 mm in thickness, 270 mm in outer diameter and about 6 m in height. For confirming the safety of the CNS, the combustion tests were carried out using the hydrogen-air mixture under the conditions in which air is introduced into the tube at 1 atmosphere, and then hydrogen gas is supplied from the gas cylinder up to the test pressures. And maximum test pressure is 0.140 MPa Gauge (G). This condition includes the design accident of the CNS. The peak pressure due to combustion is 1.09 MPa, and the design strength of the CNS channel is 3 MPa. The safety of the CNS was thus verified even if the design basis accident occurs. The pressure distribution, the stress, and the displacement of the tube were also measured.
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Rolindo, Saullo José Silva, Isabela Louise Caldeira Silva, Samuel Campos Silva, and Denise Sisterolli Diniz. "Vasculitis of the central nervous system secondary to amiopathic dermatomyositis: A case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.661.

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Context: Dermatomyositis (DM) is an idiopathic inflammatory myopathy, characterized by proximal skeletal muscle weakness, associated with a variety of characteristic skin manifestations. A form called Amiopathic Dermatomyositis (AD) is a condition that patients have cutaneous findings characteristic of DM without weakness and/or normal muscle enzymes. In turn, central nervous system (CNS) vasculitis refers to a wide spectrum of diseases that result in inflammation and destruction of the blood vessels of the brain, spinal cord and meninges. Case report: Female, 54 years old, reports for 3 months a progressive myalgia, paraparesis and edema in the proximal region of the lower limbs, evolving in the last weeks with erythematous and itchy lesions on the trunk (in shawl), feet and hands, with subsequent peeling of these (mechanic’s hands). During diagnostic investigation she presented epileptic seizures with behavioral arrest, right hemiparesis and motor aphasia. It evolved with a new stroke in the left frontoparietal region. Bilateral angiography showed points of constriction of segments of the middle cerebral artery bilaterally, compatible with CNS vasculitis. Therefore, with the exclusion of other secondary causes of arteritis, associated with the marker of positive inflammatory myopathy (Anti-Jo1) and CPK within the serum levels of normality, the diagnosis of the stroke secondary to AD was closed. Conclusions: Both CNS vasculitis and AD are rare conditions, characteristically diagnoses of exclusion, deserving to be remembered in clinical cases with singular manifestations, as reported in this case.
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Lee, Myungeun, and Gilsoo Cho. "Psychophysiologically Evaluated Visuo-Tactile Affection using Printed Fabrics." In Applied Human Factors and Ergonomics Conference. AHFE International, 2021. http://dx.doi.org/10.54941/ahfe100574.

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The present study compared to the three perceptional conditions of tactile affection−tactile tactility, visual tactility, and visuo-tactile affections−using psychological evaluation and psychophysiological methods. A comparative study was performed to fine out the differences of psychological and psychophysiological tactile perception according to the conditions of tactile perception. Furthermore, it also aims to find out the important fabric factor for tactile affection. Through the previous study, we found the fabric factors which influenced in tactile affection of fabrics: weave construction and fabric pattern. Total of six printed fabrics were developed by DTP method on naturally colored organic cotton fabrics as stimuli. Thirty participants were placed by randomized incomplete block design for the experiment. For measuring psychological affection, questionnaire was developed using a 9 points semantic differential scale. Electroencephalogram(EEG) was measured as a CNS response and electrocardiogram(ECG), skin conductance level(SCL), and photoplethysmography(PPG) were quantified as ANS responses. According to the results, perceptional condition had little effect on psychological and psychophysiological tactile perception. Significant effects on perceptional condition showed only on “showy-plain” affection and SCL response. Mostly, weave construction was more important fabric factor to perceive tactile affection than fabric pattern. However, the importance of fabric pattern also observed through the interaction effects.
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Khorsand Vakilzadeh, Majid, Hassan Salarieh, Mohsen Asghari, and Mohamad Parnianpour. "Trajectory Planning of Spine Motion During Flexion Using a Stability-Based Optimization." In ASME 2010 10th Biennial Conference on Engineering Systems Design and Analysis. ASMEDC, 2010. http://dx.doi.org/10.1115/esda2010-24371.

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A central problem in motor control is to understand how the many biomechanical degrees of freedom are coordinated to achieve a goal. A common assumption is that Central Nervous System (CNS) would minimize a performance index to achieve this goal which is called objective function. In this paper, two popular objective functions are utilized to design the optimal trajectory of trunk movements. A 3D computational method incorporated with 18 anatomically oriented muscles is used to simulate human trunk system. Inverse dynamics allows us to compute torque which is generated around Lumbosacral joint. This torque is divided among muscles by static stability-based optimization. Trunk movement from the upright standing to 30 degrees of flexion is simulated based on this method. Incorporation of the stability condition with the static optimization resulted in an increase of antagonistic activities which would increase the joint stiffness around the Lumbosacral joint in response to gravity perturbation. Results would shed light on the interaction mechanisms in muscle activation patterns, seen in various performance indices.
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Oliveira, Victória Nunes, Mellyssa Cota Elias, Heloiza Castilhoni Belique, Gabriel Lima Martins, Bianca Soares de Sá Peixoto, Luiza Siqueira Barreto de Souza, Millena Silva dos Santos, et al. "Case of aluminium poisoning, with differential diagnosis for amyotrophic lateral sclerosis (als)." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.246.

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Introduction: Essential metals in high quantities can accumulate and reach toxicity. In the CNS, they lead to neurodegeneration, causing movement and cognitive disorders. Case Report: White man, 59 years, sanitation agent, uses PPE irregularly. For 1 year presented progressive speech disorder, paresis, emaciation, dysphonia, tongue atrophy, limbs fasciculations and abnormal reflexes; normal tonus/ sensibility. Bulbar/limb electroneuromyography and serum dosage of metals in contact were requested, revealing muscles denervation, axonal diffuse polyneuropathy with postganglionic injury and elevated seric Aluminum (Al), (35,7ug/L). The management was work leave, Nortriptyline, and dietary supplementation. It evolved with reduction in seric Al (3,3ug/L); the physical examination remained unaltered. The condition stabilized after treatment. Discussion: Al exposure causes oxidative stress/neurotoxicity, leading to neuronal degeneration. Axonal sensorimotor neuropathy, progressive asthenia, emaciation, fasciculations, aphasia, ataxia, tongue atrophy, and organs injuries can be found. In this case, the clinical presentation differs from ALS because of sensibility commitment and postganglionic alteration, compatible with chronic axonal neuropathy. Conclusion: Although ALS is the most common MND, atypical cases need further investigation to diagnose and treat correctly.
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Arana, Claudya P., Ishwar K. Puri, and Swarnendu Sen. "How Do the Local Conditions Influence the Flame Synthesis of Carbon Nanostructures?" In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-60382.

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Since prepared substrates offer an appropriate method for the selective production of uniform arrays of aligned CNTs and CNFs, it is important to illustrate the influence of different catalysts on the resulting nanostructures. This investigation characterizes the activity of three catalysts — iron in alloyed form as stainless steel, nickel, and platinum — on carbon nanostructure formation under identical conditions in an ethylene/air nonpremixed flame. We have synthesized well-aligned multi-walled CNTs (on Ni) and CNFs (on stainless steel). The third transition metal Pt produces CNF structures of a different kind and its activity has not been previously characterized in flames. The catalyst and gas-phase conditions leading to the formation of these different structures are discussed.
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Araújo, Louisy Carvalho, Marina Crispim Sarmento, Nicole Sarmento Queiroga, Lucas Vinicius Rafael Figueiredo, and Michelle Salles Barros de Aguiar. "Acute disseminated encephalomielite and Covid-19 - a literature review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.396.

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Background: The infection caused by SARS-CoV-2 is associated with several neurological manifestations. Among these, acute disseminated encephalomyelitis (ADEM), an immune-mediated disease, has a reasonable incidence. In this context, the absence of direct viral infection of the CNS and late presentation of the condition corroborate to the hypothesis of an immune relationship. Objectives: Describe the relation between acute disseminated encephalomyelitis and COVID-19 infection. Design and setting: Literature review, held at the University Center of João Pessoa, located in the city of João Pessoa, Paraíba, Brazil. Methods: Through the PubMed database, using descriptors as follows: “acute disseminated encephalomyelitis” AND “COVID-19”, associated with time filter of the years 2020-2021. Results: The pathogenesis of ADEM in COVID-19 occurs through several mechanisms. One is a cross reaction between immune cells and nerve cells, which causes damage by activating the immune response and releasing protease enzymes. Another perspective is that the state of hyperinflammation activates like glial cells. In addition, an infection can trigger the production of autoantibodies against glial components, generating demyelinating lesions. In a series of cases that included 43 patients, nine had manifestations of ADEM, with a variety of clinical and radiological forms. Of these nine, on neuroimaging, all had multifocal, supratentorial white matter, four had hemorrhagic changes and two had myelitis. Conclusions: The coexistence between ADEM and COVID-19, although well established in some cases, still shows the need for studies that better clarify the relation between viral infection and brain lesions present in these clinical conditions.
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Morota, Hidetsugu, Toshimitsu Miyazono, and Tatsuro Okumura. "Utilization of CMS (Condition Monitoring System) for CBM (Condition-Based Maintenance)." In 17th International Conference on Nuclear Engineering. ASMEDC, 2009. http://dx.doi.org/10.1115/icone17-75843.

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CBM (Condition-Based Maintenance) is highly effective to make improvement utilization rate of the electric power facility. In case of CBM, it is often the case that vibration diagnosis for rotating components is direct measurement. CMS (Condition Monitoring System), which is tool for the plant performance analysis and diagnose component fault based on heat and mass balance calculations, is beneficial tool for CBM to proceed more effectively. The work is a suggestion of a new approach for CBM using CMS, provides proof-of-concept demonstration of effectiveness of a foreword looking approach to diagnostic and prognostic technology and shows effectiveness of CMS for CBM including application results.
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Xu, Songbo, Aydar Akchurin, X. W. Tangpong, Tian Liu, Weston Wood, and Wei-Hong Zhong. "Comparison of Tribological Performances of High Density Polyethylene Enhanced With Carbon Nanofibers." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-86150.

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High density polyethylene (HDPE) is widely used as bearing material in industrial application because of its low friction and high wear resistance properties. Carbon nanofiber (CNF) reinforced HDPE nanocomposites are promising materials for biomedical applications as well, such as being the bearing materials in total joint replacements. The main objective of the present study is to investigate how the wear of HDPE can be altered by the addition of either pristine or silane treated CNFs at different loading levels (0.5 wt.% and 3 wt.%). Two types of silane coating thicknesses, 2.8 nm and 46 nm, were applied on the surfaces of oxidized CNFs to improve the interfacial bonding strength between the CNFs and the matrix. The CNF/HDPE nanocomposites were prepared through melt mixing and hot-pressing. The coefficients of friction (COFs) and wear rates of the neat HDPE and CNF/HDPE nanocomposites were determined using a pin-on-disc tribometer under dry sliding conditions. The microstructures of the worn surfaces of the nanocomposites were characterized using both scanning electron microscope (SEM) and optical microscope to analyze their wear mechanisms. Compared with the neat HDPE, the COF of the nanocomposites were reduced. The nanocomposite reinforced with CNFs coated with the thicker silane coating (46 nm) at 0.5 wt.% loading level was found to yield the highest wear resistance with a wear rate reduction of nearly 68% compared to the neat HDPE.
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Rahman, Tahrima, Shasha Jin, and Vibhav Gogate. "Cutset Bayesian Networks: A New Representation for Learning Rao-Blackwellised Graphical Models." In Twenty-Eighth International Joint Conference on Artificial Intelligence {IJCAI-19}. California: International Joint Conferences on Artificial Intelligence Organization, 2019. http://dx.doi.org/10.24963/ijcai.2019/797.

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Recently there has been growing interest in learning probabilistic models that admit poly-time inference called tractable probabilistic models from data. Although they generalize poorly as compared to intractable models, they often yield more accurate estimates at prediction time. In this paper, we seek to further explore this trade-off between generalization performance and inference accuracy by proposing a novel, partially tractable representation called cutset Bayesian networks (CBNs). The main idea in CBNs is to partition the variables into two subsets X and Y, learn a (intractable) Bayesian network that represents P(X) and a tractable conditional model that represents P(Y|X). The hope is that the intractable model will help improve generalization while the tractable model, by leveraging Rao-Blackwellised sampling which combines exact inference and sampling, will help improve the prediction accuracy. To compactly model P(Y|X), we introduce a novel tractable representation called conditional cutset networks (CCNs) in which all conditional probability distributions are represented using calibrated classifiers—classifiers which typically yield higher quality probability estimates than conventional classifiers. We show via a rigorous experimental evaluation that CBNs and CCNs yield more accurate posterior estimates than their tractable as well as intractable counterparts.
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Reports on the topic "CNS condition"

1

Mahmoudi, Farhad, Mahtab Mokarram, Sadegh Sabouhi, Sara Hashemi, Parastoo Saberi, and Hadi Zamanian. Application of digital health for improving medication adherence in MS patients. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2021. http://dx.doi.org/10.37766/inplasy2021.10.0058.

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Review question / Objective: The aim of this study is to evaluate the efficacy of digital health interventions in monitoring and improving medication adherence in Multiple Sclerosis patients. Condition being studied: Multiple sclerosis (MS) is the most prevalent chronic inflammatory disease of the central nervous system (CNS), which leads to focal lesions in the white matter, characterized by selective primary demyelination with partial preservation of axons and reactive astrocytic gliosis. The disease is thought to be due to a complex interaction between different genetic and environmental factors. The prevalence of MS is rising all over the world, due on one hand to earlier diagnosis and prolonged survival, and on the other to a true increase in incidence of the disease. The diagnosis of MS remains clinical despite recent advances in diagnostics and relies on demonstrating dissemination in space and time while excluding alternative diagnoses.
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Hofmann, Nina, Robert Ambühl, Suzana Jordan, and Oliver Distler. A systematic literature review- Calcineurin inhibitors treatment in systemic sclerosis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2021. http://dx.doi.org/10.37766/inplasy2021.10.0095.

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Review question / Objective: To systematically review treatment effectiveness and adverse events of calcineurin inhibitors (CNIs) such as cyclosporine A (CsA) and tacrolimus in patients with systemic sclerosis (SSc). Condition being studied: Systemic sclerosis. Eligibility criteria: • Publications with SSc patients treated with CNIs and available information on the outcome of CNI therapy on SSc disease manifestation will be analysed.• Article types: case reports, clinical study, clinical trial, controlled clinical trial, historical article, randomized controlled trial.
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Amir, Rachel, David J. Oliver, Gad Galili, and Jacline V. Shanks. The Role of Cysteine Partitioning into Glutathione and Methionine Synthesis During Normal and Stress Conditions. United States Department of Agriculture, January 2013. http://dx.doi.org/10.32747/2013.7699850.bard.

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The objective of this research is to study the nature of the competition for cysteine (Cys), the first organic sulfur-containing compound, between its two main metabolites, glutathione (GSH) and methionine (Met). GSH plays a central role in protecting plants during various stresses, while Met, an essential amino acid, regulates essential processes and metabolites in plant cells through its metabolite S-adenosyl-Met. Our results, which are based on flux analysis and measurements of Met- metabolites, show that the flux towards Met synthesis is high during non-stress conditions, however the flux is significantly reduced under stress conditions, when there is high synthesis of GSH. Under oxidative stress the expression level of the regulatory enzyme of Met synthesis, cystathionine g-synthase (CGS) was reduced. By using three different systems, we have found that that GSH down regulates the expression level of CGS, thus reducing Met synthesis. We have found that this regulation occurs at the post-transcriptional level, and further studies have shown that it occurs at post-translationaly. To reveal how oxidative stress affects the flux towards Met and GSH, flux analysis was performed. We have found that the level of Met is significantly reduced, while the level of glutathione significantly increases during stress. Under stress conditions most of the glutathione is converted from GSH to GSSG (the oxidised form of glutathione). These results suggest that under normal growth conditions, Cys is channelled towards both pathways to support GSH accumulation and the synthesis of growth-essential Met metabolites. However, during oxidative stress, when a high level of GSH is required to protect the plants, the levels of GSH increase while those of CGS are reduced. This reduction leaves more Cys available for GSH synthesis under stress conditions. In addition we have also studied the effects of high GSH level on the transcriptome profile. The analysis revealed that GSH affects the expression level of many major genes coding to enzymes or proteins associated with photosynthesis, starch degradation, hormone metabolism (especially genes associated with jasmonate), biotic stress (especially genes associated with PR-proteins), cytochrome P450 genes, regulation of transcription and signaling (especially genes associated with receptor kinases and calcium). These results suggest that indeed GSH levels affect different pathways and metabolites in plants.
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Paul, Satashree. Anesthesia-The Gamechanger. Science Repository OÜ, October 2020. http://dx.doi.org/10.31487/sr.blog.11.

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General anesthetics mainly acts by inactivating the central nervous system (CNS) excitatory receptors while activating the inhibitory receptors of CNS. Oscillations play a major role in keeping the brain in working conditions
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Spormann, Alfred M. Factors Affecting Cis-Dichloroethene and Vinyl Chloride Biological Transformation Under Anaerobic Conditions. Fort Belvoir, VA: Defense Technical Information Center, May 2006. http://dx.doi.org/10.21236/ada635026.

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Bian, Zhiyuan, Jie Yu, Mingqi Tu, Binjun Liao, Jingmei Huang, Yongliang Jiang, and Jianqiao Fang. Acupuncture and related therapies for carpal tunnel syndrome: A protocol for systematic review and Bayesian network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2021. http://dx.doi.org/10.37766/inplasy2021.11.0094.

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Review question / Objective: We aim to compare the efficacy and safety of different acupuncture and related therapies for carpal tunnel syndrome (CTS) using systematic review and network meta-analysis (NMA). Condition being studied: CTS is a symptomatic condition caused by compression of the median nerve within the carpal tunnel. Patients with CTS typically report paresthesia or pain in distribution of median nerve distal to the wrist. Diverse non-surgical treatments and surgical decompression have been used in the management of CTS. Acupuncture, a prominent component of traditional Chinese medicine (TCM), has also been practiced when treating CTS as a complementary therapy. However, the relative treatment effects of different acupuncture methods for CTS are unclear.
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Hotz-Hart, Beat. Synthèse thématique «Conditions du marché et réglementation» du PNR «Energie». Swiss National Science Foundation (SNSF), November 2019. http://dx.doi.org/10.46446/publication_pnr70_pnr71.2019.4.fr.

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À elles seules, les solutions technologiques ne suffisent pas à transformer le système électrique suisse. L’aménagement des conditions du marché et de la réglementation est au moins aussi important. Il est impératif d’agir afin que ces dernières mènent l’évolution dans la bonne direction au moyen d’incitations et d'opportunités d'action.
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8

Liu, Zhen, Zhizhen Lv, Jiao Shi, Shuangwei Hong, Huazhi Huang, and Lijiang Lv. Efficacy of traditional Chinese exercise in patients with chronic fatigue syndrome: a protocol for a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2022. http://dx.doi.org/10.37766/inplasy2022.9.0022.

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Review question / Objective: Chronic fatigue syndrome (CFS) is a disease in which fatigue strikes or lasts for more than 6 months, accompanied by pain, sleep disturbance, anxiety, and depression. Moreover, it brings a heavy economic burden to society. Traditional Chinese exercises (TCEs) are a traditional Chinese medical treatment and have good efficacy on CFS, therefore, this systematic evaluation is to accurately evaluate the efficacy of TCEs on CFS. P: Patients with chronic fatigue syndrome. I: Traditional Chinese exercises. C: conventional exercise, acupuncture, physiotherapy, and other physical therapy methods. O: quality of life, fatigue, pain, sleep, anxiety, and depression. S: randomized controlled trials. Condition being studied: Chronic fatigue syndrome (CFS) is a disease in which fatigue strikes or lasts for more than 6 months, accompanied by pain, sleep disturbance, anxiety, and depression. Moreover, it brings a heavy economic burden to society. Traditional Chinese exercises (TCEs) are a traditional Chinese medical treatment and have good efficacy on CFS. Therefore, this systematic evaluation is to accurately evaluate the efficacy of TCEs on CFS, to provide an alternative therapy for clinical treatment of CFS.
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Nadal-Caraballo, Norberto, Madison Yawn, Luke Aucoin, Meredith Carr, Jeffrey Melby, Efrain Ramos-Santiago, Fabian Garcia-Moreno, et al. Coastal Hazards System–Puerto Rico and US Virgin Islands (CHS-PR). Engineer Research and Development Center (U.S.), December 2022. http://dx.doi.org/10.21079/11681/46200.

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The South Atlantic Coastal Study (SACS) was completed by the US Army Corps of Engineers to quantify storm surge and wave hazards allowing for the expansion of the Coastal Hazards System (CHS) to the South Atlantic Division (SAD) domain. The goal of the CHS-SACS was to quantify coastal storm hazards for present conditions and future sea level rise (SLR) scenarios to aid in reducing flooding risk and increasing resiliency in coastal environments. CHS-SACS was completed for three regions within the SAD domain, and this report focuses on the Coastal Hazards System–Puerto Rico and US Virgin Islands (CHS-PR). This study applied the CHS Probabilistic Coastal Hazard Analysis (PCHA) framework for quantifying tropical cyclone (TC) responses, leveraging new atmospheric and hydrodynamic numerical model simulations of synthetic TCs developed explicitly for the CHS-PR region. This report focuses on documenting the PCHA conducted for CHS-PR, including the characterization of storm climate, storm sampling, storm recurrence rate estimation, marginal distributions, correlation and dependence structure of TC atmospheric-forcing parameters, development of augmented storm suites, and assignment of discrete storm weights to the synthetic TCs. As part of CHS-PR, coastal hazards were estimated for annual exceedance frequencies over the range of 10 yr⁻¹ to 10⁻⁴ yr⁻¹.
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Kengsakul, Malika, Gatske Nieuwenhuyzen – de Boer, and Heleen van Beekhuizen. Radiological factors associated with residual disease after cytoreductive surgery for advanced ovarian cancer. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2023. http://dx.doi.org/10.37766/inplasy2023.1.0059.

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Review question / Objective: Which radiological factors associated with incomplete cytoreduction (gross residual disease) after cytoreductive surgery (CRS) for advanced ovarian cancer? Condition being studied: Findings of CT scan and discussion in the multidisciplinary tumor board meeting (MDO) are crucial to determine the therapeutic strategy for individual ovarian cancer patients. Preferably, patients undergo primary cytoreductive surgery (CRS) followed by adjuvant chemotherapy. However, when complete cytoreduction is not considered feasible, neoadjuvant chemotherapy followed by interval cytoreductive surgery and adjuvant chemotherapy is indicated. In patients with advanced stage epithelial ovarian cancer (EOC), maximal cytoreduction to no gross residual tumor (complete cytoreduction) is known to associated with the best overall survival.
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