Journal articles: 'Cnido'

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González Saavedra, Berta. "Juan Antonio Álvarez-Pedrosa Núñez (ed. & trad.), Ctesias de Cnido. Relaciones de la India, Madrid, Dykinson, 2018, 173 pp. [ISBN: 978-84-9148-496-7]." Gerión. Revista de Historia Antigua 38, no. 1 (March 31, 2020): 336–37. http://dx.doi.org/10.5209/geri.68598.

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Becerra Romero, Daniel. "El díkairon en la obra Indika de Ctesias de Cnido. Propuesta de identificación." Emerita 75, no. 2 (December 18, 2007): 255–72. http://dx.doi.org/10.3989/emerita.2007.v75.i2.194.

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Santoni, Anna. "Miti omerici in Agatarchide di Cnido De Mari Erythraeo 1.7. Testimonianze della filologia alessandrina." Gaia : revue interdisciplinaire sur la Grèce Archaïque 7, no. 1 (2003): 387–403. http://dx.doi.org/10.3406/gaia.2003.1432.

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Catananti, Cesare. "L’antropologia alla base della medicina: un dibattito antico ed attuale." Medicina e Morale 45, no. 6 (December 31, 1996): 1135–50. http://dx.doi.org/10.4081/mem.1996.894.

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La storia della medicina è stata costantemente punteggiata da un vivace dibattito su quelli che sono i contenuti del sapere medico, su quello che è il corretto esercizio applicato di quel sapere e sul se e sul come quel sapere e quell’agire si integrino in un’ottica antropologica. Questo costante richiamo ad una umanizzazione dell’assistenza medica tradisce il profondo bisogno di una medicina centrata sull’uomo e non sulla malattia. Un bisogno molto antico dato che già nel V sec. a.C. le divergenze tra la scuola medica di Cos e quella di Cnido vertevano proprio su tale questione. L’autore dopo aver ripercorso brevemente in questa prospettiva la storia della medicina, mette in luce come con l’individuazione e la diffusione del metodo scientifico, quantitativo, nel XVII sec. gli aspetti tecnici, economici, sociologici hanno prevalso su quelli relazionali. Mentre, a suo giudizio, è nella ricerca delle integrazioni psico-biologiche che il medico doctus ed expertus potrà far valere la sua sapientia, scientia e sapienza cordis tra loro amalgamate; falitando così il suo rapporto con il paziente il quale sarà caratterizzato non da un atteggiamento paternalistico o autoritario ma di paritaria empatia. Si tratta allora di costruire una tecnè che poggi in maniera armonica ed equilibrata su due pilatri: quello della conoscenza scientifica e quello dell’ethos umanitario. una medicina, quindi, che faccia coincidere antropologia e tecnologia.

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Acuña, F. H., A. C. Excoffon, and L. Ricci. "Composition, biometry and statistical relationships between the cnidom and body size in the sea anemone Oulactis muscosa (Cnidaria: Actiniaria)." Journal of the Marine Biological Association of the United Kingdom 87, no. 2 (April 2007): 415–19. http://dx.doi.org/10.1017/s0025315407055087.

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This study analyses the possible relationships between body size and length of cnidae from different tissues of the sea anemone Oulactis muscosa. We describe the cnidom, providing new qualitative and quantitative data. Our description adds spirocysts for tentacles and acrorhagi, and is more precise about the ranges and types of basitrichs, microbasic b-mastigophores, and holotrichs. We distinguish two types of holotrichs in the acrorhagi, and differentiate between microbasic b-mastigophores and basitrichs in the actinopharynx and mesenterial filaments. A relationship between cnida length and body weight was not demonstrated. The results are based on a complete account of cnida types from all tissues, and considering the great number of capsules measured (5400) and the modern statistical tools employed, we think that a normal distribution of cnida lengths is uncommon, perhaps refuted. This finding is very important when a quantitative analysis of cnidae is necessary and an adequate statistical tool must be used. We have shown that generalized linear models are an alternative and therefore analyses can be done with parametric methods despite the non-normal distribution of cnida size. The use of these statistical tools should be generalized since appropriate package for analyses (like the R package) are available from the web and the obtained results are robust and powerful.

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Ngomo Fernández, Esteban. "Juan Antonio Álvarez-Pedrosa Núñez, "Ctesias de Cnido. Relaciones de la India", Edición Bilingüe, Madrid: Clásicos Dikynson, 2018, 173 págs. ISBN 978-84- 9148-946-7." Cuadernos de Filología Clásica. Estudios griegos e indoeuropeos 29 (June 6, 2019): 209–11. http://dx.doi.org/10.5209/cfcg.63597.

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Vagge, Aldo, Lorenzo Ferro Desideri, Paolo Nucci, Massimiliano Serafino, Giuseppe Giannaccare, Andrea Lembo, and Carlo Traverso. "Congenital Nasolacrimal Duct Obstruction (CNLDO): A Review." Diseases 6, no. 4 (October 22, 2018): 96. http://dx.doi.org/10.3390/diseases6040096.

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Congenital nasolacrimal duct obstruction (CNLDO) is a common condition causing excessive tearing or mucoid discharge from the eyes, due to blockage of the nasolacrimal duct system. Nasolacrimal duct obstruction affects as many as 20% children aged <1 year worldwide and is often resolved without surgery. Available treatment options are conservative therapy, including observation, lacrimal sac massage and antibiotics, and invasive therapy. Observation, combined with conservative options, seems to be the best option in infants aged <1 year. Meanwhile, in children aged >1 year, nasolacrimal probing successfully addresses most obstructions. However, the most favorable timing for probing remains controversial. To alleviate persistent epiphora and mucous drainage that is refractory to probing, repeat probing, silicone tube intubation, balloon catheter dilation or dacryocystorhinostomy can be considered as available treatment options. Our review aims to provide an update to CNDO management protocols.

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Valcheva, K. P., and S. V. Murgova. "Conservative Treatment for Congenital Nasolacrimal Duct Obstruction – Factors Affecting the Success." Acta Medica Bulgarica 48, no. 2 (July 1, 2021): 25–28. http://dx.doi.org/10.2478/amb-2021-0019.

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Abstract Aim To examine the success rate and factors affecting the effect of conservative treatment for congenital nasolacrimal duct obstruction (CNLDO) in children. Methodology A prospective study was made on 167 eyes of 131 patients with clinical signs of CNLDO. All of them were initially treated nonsurgically with Crigler massage. The curative effect of this management was evaluated on the basis of no history of watery eyes, negative regurgitation test, and dye disappearance test 0 or 1 grade. Exploratory analyses assessed whether baseline characteristics including age, gender and laterality were associated with the probability of CNLDO resolving without surgery. If the nonsurgical treatment failed, probing was done in the Eye Clinic in Pleven. Results The conservative treatment for CNLDO with Crigler massage was successful in the majority of treated cases – in 115 out of 167 eyes with CNLDO (68,9%). The remaining 52 (31,1%) eyes were probed. Age (p = 0,001) and laterality (p = 0,001) were found to be associated with resolution of the clinical signs. Conclusions Nonsurgical management for CNLDO was successful initial treatment in patients with this pathology. The Crigler massage was more effective in children up to 12 months of age with unilateral obstruction.

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Sathiamoorthi, Saraniya, Ryan D. Frank, and Brian G. Mohney. "Incidence and clinical characteristics of congenital nasolacrimal duct obstruction." British Journal of Ophthalmology 103, no. 4 (June 6, 2018): 527–29. http://dx.doi.org/10.1136/bjophthalmol-2018-312074.

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Background/aimsThe literature on the prevalence and demographics of congenital nasolacrimal duct obstruction (CNLDO) is 30–70 years old and largely comprises small sample sizes. This study provides epidemiological findings of this common disorder from the largest cohort reported to date.MethodsThe medical records of all children (<5 years of age) residing in Olmsted County, Minnesota, when diagnosed with CNLDO from 1 January 1995 through 31 December 2004, were reviewed.ResultsOf 17 713 newborns born during the 10-year study period, 1998 were diagnosed with CNLDO, yielding a birth prevalence of one in nine live births. The diagnosis was made in approximately 90% by a primary care physician, at a median age of 5 weeks, with no gender predilection. Compared with the reference population, CNLDO was associated with premature birth (p=0.005) and was more prevalent among Caucasians (p<0.001). Two-thirds of patients initially presented with discharge alone, 18% with tearing alone and 15% with both discharge and tearing.ConclusionsIn this large population-based cohort, CNLDO occurred in one in nine live births with no gender predilection. Prematurity and Caucasian race were associated with the development of CNLDO. Mucopurulent discharge was a much more common feature than tearing at initial presentation.

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Pawar, Prachi, Aruna Patil, Mihir Patel, and Saurabh Shah. "Use of Oil as a Lubricant makes Lacrimal Sac Massage Efficient in Congenital NasoLacrimal Duct Obstruction (CNLDO)." MVP Journal of Medical Sciences 1, no. 1 (January 1, 2014): 13. http://dx.doi.org/10.18311/mvpjms/2014/v1/i1/830.

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Introduction: Congenital NasoLacrimal Duct Obstruction (CNLDO) is a frequent entity in the paediatric age. CNLDO has a 20% to 30% incidence rate out of which only 1% to 6% become symptomatic.1 The 4% of premature infants are affected with CNLDO.2 The management of failed Crigler's Sac massage is probing, secondary probing, external DCR and with or without intubation is well known to all. To avoid the sequelae of CNLDO, cure of CNLDO is mandatory. Hence the aim of the study is primary cure for CNLDO by using specific treatment of Crigler's Sac massage with Oil is emphasised. Method: This study was about 140 eyes and in each group, 70 eyes were enrolled with lost to follow up considerations. Patients had been selected and randomised alternatively when visited ophthalmology OPD. The CNLDO patients were selected from the age group ranged 1 to 9 months. Follow up of all patients was taken every month up to 15 months of age. Each and every patient from both the groups had to complete the formality of clinical consultation, doctors counselling to parents specially mothers explaining the procedure of sac massage and taking a live demonstration by mother/ parent hence confirming the proper technique to be followed at home. Results: In group A, Standard Crigler's Method was used only on 54 eyes out of enrolment of 70 eyes. In group B, Standard Method with add on therapy of oil massage had been given to 66 eyes out of 70. In group B, cure rate was found in 60(91%) which was significantly differing from the cure rate of group A 30(56%) by Standard Crigler's Method at P<0.001. Complications were found in 20 eyes in group A and in group B only one patient showed complication unrelated to the treatment of CNLDO used by the patients in this group. No significant difference was seen in the sex distribution in relation to CNLDO at P>0.05. Conclusion: The primary need of Crigler's Sac Massage using Oil has given the importance towards good compliance and success of curing CNLDO.

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Nakayama, Tomomichi, Akihide Watanabe, Saul Rajak, Yukito Yamanaka, and Chie Sotozono. "Congenital nasolacrimal duct obstruction continues trend for spontaneous resolution beyond first year of life." British Journal of Ophthalmology 104, no. 8 (November 1, 2019): 1161–63. http://dx.doi.org/10.1136/bjophthalmol-2019-314980.

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PurposeTo investigate spontaneous resolution of congenital nasolacrimal duct obstruction (CNLDO) beyond 12 months of age in Japanese infants.MethodsRetrospective, observational case series. We retrospectively reviewed the clinical records of patients diagnosed with CNLDO beyond 12 months of age at Kyoto Prefectural University Hospital, Kyoto, Japan. This study involved 155 cases of CNLDO in 133 Japanese infants diagnosed with CNLDO. All patients chose intervention with either dacryoendoscopic guided probing and stenting or conservative management. The proportion and age of patients who had spontaneous CLNDO resolution were analysed.ResultsThe patients were divided into two groups: (1) 62 patients with 70 obstructed nasolacrimal ducts (45%) in whom spontaneous resolution occurred and (2) 71 patients with 85 obstructed nasolacrimal ducts (55%) who underwent dacryoendoscopic guided probing and stenting. The mean age of spontaneous resolution was 17.8±5.3 months (range: 12.0–35.4 months). Dacryoendoscopic guided probing and stenting were successful in 83/85 (97.6%) of cases.ConclusionsSpontaneous resolution of CNLDO can occur in 45% of infants over the age of 12 months. Dacryoendoscopic guided stenting also has high success rates in this patient group, and both treatment options can be proposed to caregivers.

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Galindo-Ferreiro, Alicia, Teresa Palencia-Ercilla, Livia Mendoza Ferreira, Alberto Galvez-Ruiz, Denise C. M. Zornoff, Rajiv Khandekar, and Silvana A. Schellini. "A Survey of Management of Congenital Nasolacrimal Duct Obstruction by Pediatric Primary Health Care Providers in Spain." European Journal of Ophthalmology 27, no. 4 (December 20, 2016): 502–5. http://dx.doi.org/10.5301/ejo.5000915.

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Purpose To survey the management of congenital nasolacrimal duct obstruction (CNLDO) by pediatric primary health care providers in Spain. Methods This was a descriptive study using a web-based questionnaire to evaluate the perceptions of the members of the Pediatric Primary Care Society in Castilla-León, Spain (APAPCYL), regarding management of CNLDO. The questionnaire contained 14 direct questions and was sent by e-mail to all the pediatricians. All the responses were analyzed by the frequency of occurrence and percentages. Results Ninety physicians responded to the questionnaire. Massage 2 or 3 times a day was the initial treatment advised by 60.47% of pediatricians. Nearly half of the pediatricians recommended continuing massage until symptoms resolved. Fewer than 50% of children required referral to an ophthalmologist. Reasons for an ophthalmic consult included persistence of symptoms among 87.21% of pediatricians and parental/guardian request among 10.5% of pediatricians. According to 45.6% of pediatricians, their knowledge about CNLDO is limited, and 92.2% would like to receive further training on CNLDO. Conclusions Massage was the main initial treatment for managing CNLDO among pediatricians. The outcomes of this survey indicated that massage fails in fewer than 50% of patients and an ophthalmic referral is required for these cases.

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Anthony, S. E. "Cnida sequestration in aeolid nudibranchs: variability and retention time of sequestered cnidae in the opalescent sea slug, Hermissenda crassicornis (Gastropoda, Nudibranchia)." Canadian Journal of Zoology 98, no. 12 (December 2020): 808–14. http://dx.doi.org/10.1139/cjz-2020-0010.

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Aeolid sea slugs can isolate and store stinging cnidae obtained from their cnidarian prey, presumably for their own defence. There are 30 different varieties of cnidae, identified by their unique structure. The aeolids engulf the cnidae and store them in a functional state at the tips of their cerata. Although the process of cnida sequestration is reasonably well understood in aeolids, two critical questions remain: (1) are cnida types uniformly distributed among the cerata and (2) how long do sequestered cnidae persist? I collected opalescent sea slugs (Hermissenda crassicornis (Eschscholtz, 1831)) from Barkley Sound, British Columbia, Canada, and determined the cnida complements in four cerata per individual by microscope. The cnida complements differed between cerata from different body regions within the individual (values of Whittaker’s dissimilarity index from 2.5% to 36.3%). Furthermore, the cnidae varieties in low abundances are not consistently present within an individual. I also found that H. crassicornis fed a non-cnidarian diet lost cnidae over time, but the cnidarian-fed individuals did not: 3 of 10 H. crassicornis on the non-cnidarian diet lacked cnidae completely at 42 days. Future studies of cnida sequestration should be mindful that one ceras does not give an adequate representation of the distribution of sequestered cnidae.

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Natarajan, Kaviyapriya, Nirupama Kasturi, and Sujatha Sistla. "Assessment of Perinatal Clinical Characteristics, Perinatal Risk Factors, and Microbial Profile in Congenital Nasolacrimal Duct Obstruction in a Tertiary Care Center: A Descriptive Study." Korean Journal of Ophthalmology 36, no. 4 (August 5, 2022): 366–73. http://dx.doi.org/10.3341/kjo.2022.0013.

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Purpose: To assess the perinatal risk factors, clinical characteristics, and microbial profile in congenital nasolacrimal duct obstruction (CNLDO).Methods: A prospective observational study was conducted in pediatric patients of age <5 years. After a thorough clinical evaluation, the diagnosis of the CNLDO was confirmed by a Jones dye test or fluorescein dye disappearance test. A microbiological culture of lacrimal sac resurge was done with a sterile swab stick without touching the lid margins. Antibiotic susceptibility was then performed for the standard antibiotics.Results: Seventy-one eyes of 52 children were included in the study. The mean age was 3.4 months. Our research found an equal number of cases born via spontaneous vaginal delivery and Caesarean section. Nine children (17.3%) had associated systemic and ocular anomalies. The number of cultures that were positive for any growth was 19 (27%). The most common isolate was Streptococcus pneumoniae which constituted eight cases (42%), followed by Pseudomonas aeruginosa (15.8%), and Escherichia coli (10.5%). Other organisms that grew were Klebsiella pneumoniae, Staphylococcus aureus, Staphylococcus epidermidis and nonfermenting gram-negative bacilli. Gram-positive organisms were susceptible to ciprofloxacin, amoxiclav, and oxacillin, and most of them were resistant to erythromycin. In comparison, gram-negative organisms showed 62.5% resistance and 37.5% susceptibility to ciprofloxacin.Conclusions: CNLDO was more commonly unilateral, in male, preterm, and normal birth weight infants. Bilateral CNLDO was more commonly associated with coexisting ocular or systemic anomalies. Prematurity, delivery by Caesarean section, and presence of congenital anomalies were associated with a prolonged course. S. pneumoniae was the predominant isolate in our patient population.

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Zuazo, Francisca, Osiris Olvera Morales, José L. Tovilla Canales, and Ángel Nava Castañeda. "Management of Congenital Nasolacrimal Duct Obstruction with Probing, Experience in a Mexican Eye Center." Nepalese Journal of Ophthalmology 11, no. 2 (December 31, 2019): 189–96. http://dx.doi.org/10.3126/nepjoph.v11i2.27827.

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Objective: To describe the management, complications and prognosis of lacrimalprobing in patients with congenital nasolacrimal duct obstruction (CNLDO). Materials and Methods: Retrospective, observational and analytical study. We studied the prevalence, symptoms and signs, both before and after probing, in patients with CNLDO diagnosed between 2010 and 2017 at Instituto Fundación Conde deValenciana. Results: The prevalence at our hospital of congenital nasolacrimal duct obstruction in children less than 1 year of age was 16.1%. 71 eyes of 56 patients undergoing probing were analyzed. 61% of patients were male. The right eye was affected in 46.4%.The average age of diagnosis of CNLDO was 10.2±7.6 months. 84.5% consulted for excessive tearing and 73.2% because of eye discharge. On ophthalmological examination, 71.8% had increased tear meniscus and 45.1% had discharge from punctum when digital pressure was applied to the lacrimal sac. The average age at the time of probing was 14.1±8.4 months. Subsequent to the probing, only 21.1% reported presence of tearing and 5.6% reported ocular discharge, both with a statistically significant reduction (p<0.05 from pre-op). After probing, only 16.9% of eyes had increased tear meniscus and 11.3% presented discharge from punctum after pressure at the lacrimal sac. Both decreases were statistically significant (p<0.05). 2 eyes (2.82%)of 2 patients required a second probing to obtain full resolution. Conclusion: Probing was successful in 76.1% of eyes. Success was observed even inpatients over 2 years of age. There was a statistically significant decrease of both signs and symptoms of CNLDO with lacrimal probing.

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Shrestha, Koshal, Binita Bhattarai, Laxmi Devi Manandhar, Salma KC Rai, Arniko Pandey, and Shanti Gurung. "Outcome of probing and syringing in congenital nasolacrimal duct obstruction at various age groups in a tertiary eye center in Western Nepal." Asian Journal of Medical Sciences 9, no. 6 (October 29, 2018): 57–61. http://dx.doi.org/10.3126/ajms.v9i6.20508.

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Background: Congenital nasolacrimal duct obstruction (CNLDO) is one of the commonest problems encountered in daily ophthalmology practice. Though probing and syringing is the mainstay of management of CNLDO, there is no clear guideline about the optimal time to perform.Aims and Objective: To evaluate the efficacy of probing and syringing in cases of congenital nasolacrimal duct obstruction in various age groups.Materials and Methods: In this prospective, hospital based, interventional, cross-sectional study done over a period of 2 years (July 2015- June 2017), children of various age ranging from 10 days to 8 years who underwent probing and syringing under general anesthesia for CNLDO refractory to conservative measures were included. Results: Children of as young as 10 days to as older as 8 years underwent probing and syringing with male to female ratio of 1.2:1. Overall success was 80.6% (58/72) which was statistically significant when analyzed with age (P = 0.006). Majority of cases with successful outcome were below 24 months of age (90.62%). There was predominance of membranous obstruction (128/194) over bony obstruction (66/194). Conclusions: Nasolacrimal duct probing under GA is a safe and viable option as a primary treatment modality for CNLDO. Though the success of probing is high in the younger children, it’s worthwhile to consider the same in older children at least up to 5 years of age before going for more invasive procedure like DCR surgery since more than 2 third of probing has successful outcome up to that age.Asian Journal of Medical Sciences Vol.9(6) 2018 57-61

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Valcheva, Krasina P., and Snejana V. Murgova. "Refraction in Children with Unilateral and Bilateral Congenital Nasolacrimal Duct Obstruction." Journal of Biomedical and Clinical Research 12, no. 1 (July 1, 2019): 47–52. http://dx.doi.org/10.2478/jbcr-2019-0007.

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Summary The study aimed to identify the type of refraction in children with unilateral and bilateral congenital nasolacrimal duct obstruction (CNLDO) who underwent nasolacrimal duct probing. One hundred and twelve children aged 1.8 to 13 years, diagnosed with CNLDO, were included in a retrospective study. All the patients had their visual acuity examined, and their refractive status was evaluated. The refractive errors of both eyes were noted, followed by an appropriate management plan. Of the 112 children, 79 (70.5%) had a unilateral obstruction, and 33 (29.5%) had bilateral obstruction. Nine children (11.4%) in the former group and six children (18.2%) in the latter group were with visual acuity <0.8. The most frequent refractive error among the studied children was hyperopia. No statistically significant difference (p>0.05) between refraction of the two eyes in the evaluated children were found. Amblyopia risk factors were identified in 9 of the patients (8.0%). CNLDO did not adversely affect the refractive status. However, amblyogenic risk factors were found more often in our patients, as compared to general populations. Therefore, a detailed evaluation should be performed to find out these risk factors.

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Schleker, Wolfgang, and Jörg Fleischhauer. "Zum Circulardichroismus von Disulfidbrücken in Proteinen. Teil 2. Vergleichende CNDO/S- und INDO/S-CI-Rechnungen." Zeitschrift für Naturforschung A 42, no. 4 (April 1, 1987): 361–66. http://dx.doi.org/10.1515/zna-1987-0404.

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Rotatory strengths for H2S2 conformers based on X-ray data for ribonuclease A, 2-, and 4-zinc-insuline-dimers have been calculated with some CNDO/S- and INDO/S-versions. The best agreement between their calculated signs and those predicted by the quadrant rule and Rauk’s valence basis set ab initio calculations are found with the CNDUV-version of CNDO/S. A choice of β0s = - 11.5 eV within this method improves the calculated transition wavelengths compared to observed ones.

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Bandeira, Sílvia Franco Dórea. "O PAPEL DO ASSISTENTE SOCIAL NA CENTRAL DE NOTIFICAÇÃO, CAPTAÇÃO E DISTRIBUIÇÃO DE ÓRGÃOS DA BAHIA." Brazilian Journal of Transplantation 11, no. 4 (September 1, 2008): 1023–27. http://dx.doi.org/10.53855/bjt.v11i4.311.

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Artigo que trata do desenvolvimento do trabalho de doação/transplante de órgãos e tecidos realizado pela Central de Notificação, Captação e Distribuição de Órgãos da Bahia (CNCDO). Este trabalho objetiva informar e avaliar o ingresso do Assistente Social nesse processo, visando dinamizar o sistema de doação e dar assistência social à coletividade, na área da doação de órgãos. A metodologia de trabalho do Serviço Social envolve palestras, seminários e contatos corpo-a-corpo com indivíduos durante todo o processo de doação, possibilitando o acesso a informações e viabilizando o esclarecimento do papel do Assistente Social na CNCDO e versando sobre a doação / transplante, cuja tônica é educar o ser humano para uma prática solidária e amorosa, no momento em que se pode salvar uma vida.

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Yang, Weiming, Li Shen, Anken Wang, Meiyan Li, and Chenhao Yang. "Bacterial Culture of Tear Duct Infections Secondary to Congenital Nasolacrimal Duct Obstructions." Journal of Ophthalmology 2022 (March 28, 2022): 1–5. http://dx.doi.org/10.1155/2022/9954634.

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Purpose. To investigate the microbial profile of congenital nasolacrimal duct obstruction (CNLDO) in Chinese children. Methods. We retrospectively reviewed the medical records of 330 consecutive children (330 eyes) who were diagnosed with tear duct infections secondary to CNLDO and were admitted to the Children’s Hospital of Fudan University from January 2013 to January 2020. Bacterial cultures were grown from tear duct samples of each patient. Samples from conjunctival secretions were cultivated on blood or chocolate agar. Clinically significant bacterial growth was reported. Results. Of the 330 eyes considered, 62.7% (207/330) were associated with positive bacterial cultures. A total of 223 isolates were detected from 207 culture-positive eyes. Among the 223 isolates, 52.0% (116/223) were Gram-positive bacteria and 47.1% (105/223) were Gram-negative bacteria. The most prevalent Gram-positive bacteria were Streptococcus viridans (67 isolates, 30%), followed by Staphylococcus aureus (36 isolates, 16.1%) and Streptococcus pneumoniae (5 isolates, 2.2%). The most prevalent Gram-negative bacteria were Neisseria (nonpathogenic) (25 isolates, 11.2%), followed by Escherichia coli (16 isolates, 7.2%) and Haemophilus influenzae (16 eyes, 7.2%). Antibiotic susceptibility test results suggested that both Gram-positive and Gram-negative bacteria were highly sensitive to most of the tested antibiotics. Conclusions. S. viridans and S. aureus are the most prevalent bacteria in tear duct infections secondary to CNLDO. Broad-spectrum antibacterial eye drops are suggested as empirical antibiotic treatments.

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Bánhegyi, Györgi, János Ángyán, and Márton Kajtár. "Structure and ring inversion of 2-pyrrolidone. Semiempirical quantum chemical study and analysis of X-ray data." Collection of Czechoslovak Chemical Communications 51, no. 2 (1986): 249–63. http://dx.doi.org/10.1135/cccc19860249.

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The equilibrium structure and the ring inversion potential of the 2-pyrrolidone molecule has been studied by the semiempirical CNDO/2 and INDO methods. The calculated geometrical parameters are compared with experimental X-ray data with earlier Consistent Force Field (CFF) results. The ring inversion is analyzed in terms of two types of puckering coordinates. The CNDO/2 method was found to yield a strongly nonplanar 2-pyrrolidone ring due to the overestimation of the amide pyramidality while INDO calculations led to a slightly nonplanar ring with an extremely low barrier of inversion.

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Dive, G., and C. L. Lapière. "Nouvelle version du programme CNINDO." Bulletin des Sociétés Chimiques Belges 89, no. 2 (September 1, 2010): 85–87. http://dx.doi.org/10.1002/bscb.19800890201.

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Israr, Muhammad, Khalil Khan Zahir, Adnan Khattak, and Irfanullah Khattak. "Initial Probing In Children Presenting At the Age of Three To Four Years." American Journal of Health, Medicine and Nursing Practice 7, no. 3 (February 18, 2022): 16–20. http://dx.doi.org/10.47672/ajhmn.930.

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Objective: The aim of this study is to find out the ration of success in the initial probing for the congenital nasolacrimal duct obstruction at age 25th month to 60th month. Methodology: The study was prospective non-comparative interventional case series. The study included 59 eyes of 47 patients who visited the Ophthalmology HMC Peshawar in 2020. The patients were labelled as CNLDO with history of epiphora and or discharge since birth or first few days of life. The diagnosis was confirmed with evaluation in which it was assessed that there is no other associated adnexal issue like conjunctively congestion. Examination also included tear meniscus height and resurge test. Results: In prospective non-comparative interventional case series 52 eyes of 41 patients between the ages of 25 to 60 months with CNLDO were probed. Most of the patients were females i.e. 27. Most of the obstructions were of complex type i.e. 32 while 20 patients were of membranous type. Patients with bilateral CNLDO were 11. Successes ratio of probing in membranous type of obstruction was 90% i.e. 18 eyes got cured while two eyes needed repeated probing. While in case of complex obstruction the success ratio was, 32.2 % i.e. only 10 patients got cured out of 32 patients. Overall success ratio was 54% i.e 28 of 54. Conclusion: Children presenting with congenial nasolacrimal duct obstruction in older ages should be probed initially.

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Chmurzyński, Lech, Adam Liwo, Alicja Wawrzynów, and Anna Tempczyk. "Notizen: CNDO/S-CI-nPDQ Studies of the Solvation Effect on the UV Spectra of Pyridine N-Oxide and its Complexes with Proton." Zeitschrift für Naturforschung B 45, no. 5 (May 1, 1990): 719–20. http://dx.doi.org/10.1515/znb-1990-0523.

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Using the n-PDQ model, in which the solvent is simulated by several point dipoles and quadrupoles, we have estimated the shift of the UV bands of pyridine N-oxide (PyO), its cationic acid (PyOH+), and homoconjugated cation (PyOHPyO+) caused by the solvent (acetonitrile). We have calculated the UV spectra of both unsolvated and solvated species by the CNDO/S-CI and CNDO/S-CI-nPDQ method, respectively. We have found that all the bands of all the species under study are blue-shifted on solvation. The most significant is the shift of the long-wave π→π* bands of pyridine N-oxide.

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Noleto Rosa, Telma, and Volnei Garrafa. "Bioética e Confidencialidade do Doador Cadáver em Transplantes Renais no Brasil." Revista Latinoamericana de Bioética 11, no. 21 (July 15, 2011): 98–105. http://dx.doi.org/10.18359/rlbi.999.

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Objetivo - Analisar a confidencialidade nos transplantes renais com doadores cadáveres. MÉTODOLOGIA – Foram aplicados 60 questionários com participantes escolhidos aleatoriamente, divididos em três grupos: pacientes em lista de espera para transplantes, pacientes transplantados renais e familiares dos doadores. RESULTADOS - No grupo de pacientes em lista de espera, 85% manifestaram interesse em conhecer a identidade do doador; no grupo de pacientes transplantados, apenas 45% manifestaram interesse; no grupo de famílias doadoras, 55% manifestaram vontade de conhecer o receptor. A Central Nacional de Notificação, Captação e Distribuição de Órgãos (CNCDO) foiindicada por 61.7% dos participantes como responsável pela identificação do doador. CONCLUSÃO - O criterio da decisão compartilhada sobre a identificação ou não do doador cadáver, com a intermediação do Estado por meio das CNCDO, é o mais condizente com a opinião dos sujeitos que responderam à amostra estudada.

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Yosa-Reyes, Juvenal, Diana Carolina Clavijo-Buriticá, Carlos Manuel Estévez-Bretón Riveros, and Orlando Emilio Acevedo. "Métodos semiempíricos para la evaluación rápida de orbitales frontera en la clasificación de agonistas y antagonistas de la subunidad NR1 de los receptores iGluR-NMDA." Universitas Scientiarum 16, no. 1 (January 1, 2011): 5. http://dx.doi.org/10.11144/javeriana.sc16-1.smft.

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The ionotropic glutamate receptors activated by N-Methyl-D-Aspartate (iGluR-NMDA) are of great importance in pharmacology since they are involved in neurodegenerative and neuropsychiatric disorders; they even participate in processes such as synaptic plasticity that are essential for memory formation. Subunit NR1 iGluRs-NMDA is of paramount importance for the appropriate activation of this type of receptors; in fact, many of the pharmaceutical products studied for the abovementioned disorders are targeted specifically to the NR1 subunit. Previous studies have shown that the lowest energy unoccupied molecular orbital (LUMO) can be used as a parameter to estimate the agonist and antagonist activity of the NR1subunit. Objective. Evaluate the semiemprical method CNDO for the rapid calculation of the LUMO energy with the aim of preparing a simple model for the in silico design of new pharmacological substances. Materials and methods. 168 molecules with agonist and antagonist activity in the NR1 subunit were selected. Energy of each structure was optimized and then we calculated the energy of the frontier orbital, the LogP, total energy, capacity of forming hydrogen bonds, binding energy, and dipolar moment. Results. We demonstrate that LUMO energy is enough for discriminating agonist and antagonist molecules of the NR1 subunit and that the CNDO method evaluates these properties in a rapid and efficient way. Conclusions. The CNDO method facilitates a rapid calculation, enabling a future development of effective procedures for the characterization of potential pharmacological substances acting on this particular site. Key words: iGluR-NMDA, LUMO, agonist, antagonist, CNDO

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Fehniger, Todd A., Robert K. Stuart, Sarah A. Cooley, Jeffrey S. Miller, Julie Curtsinger, Timothy Mark Hillman, Nova Silver, et al. "Preliminary Results of a Phase 1/2 Clinical Trial of Cndo-109-Activated Allogeneic Natural Killer Cells in High Risk Acute Myelogenous Leukemia Patients in First Complete Remission." Blood 124, no. 21 (December 6, 2014): 2320. http://dx.doi.org/10.1182/blood.v124.21.2320.2320.

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Abstract BACKGROUND We previously reported that resting human peripheral blood NK cells can be primed to kill NK-resistant tumor cells by co-incubation with a lysate of the leukemia cell line CTV-1. CNDO-109 is a clinical-grade CTV-1 lysate that primes NK cells ex-vivo to kill NK-resistant acute myeloid leukemia (AML) cells. CNDO-109-activated NK cells can be cryopreserved and remain primed when thawed. Incubation or treatment with IL-2 is not required. We report preliminary safety, outcome and NK chimerism data from an ongoing Phase 1/2 transitional clinical trial of CNDO-109-NK cells. METHODS A 3x3 dose escalation phase 1 trial was opened in 2013 for patients with AML in 1st CR with high-risk disease and no conventional treatment options. Patients were given preparative chemotherapy of cyclophosphamide and fludarabine on Study Days -6 to -2, followed on day 0 by a single dose of CNDO-109-activated NK cells at the following doses; cohort 1 = 3×105, cohort 2 = 1×106, cohort 3 = up to 3×106 cells/kg recipient body weight. The MTD will set the dose for the transitional phase 2 trial. CNDO-109-NK cells were generated from a single apheresis collection from HLA-haploidentical related donors. NK cells were isolated with anti-CD56 microbeads (CliniMACS, Miltenyi Biotec) and co-incubated with CNDO-109 lysate (Coronado Biosciences) overnight under cGMP conditions. After lysate removal cells were cryopreserved in dosed aliquots and released for infusion. Exogenous IL-2 was not used. Quality control testing of the final product included NK purity (>50%), viability (> 70%), potency, sterility, mycoplasma and endotoxin. Residual T cell contamination (<104 cells/kg patient body weight) was a lot release safety criterion. Patients were assessed for safety and efficacy whilst expansion, proliferation and persistence of donor NK cells were assayed by molecular-based chimerism techniques, and by flow cytometry, where informative markers were available. Pre- and post-treatment samples from cohort 3 patients are being tested for flow cytometric and molecular MRD (University of Washington - Walter, R.B.2013 and NextGene Sequencing). RESULTS Seven eligible patients have been enrolled. All products met lot release and contained activated NK cells as determined by killing of NK resistant Raji cells as well as increased expression of CD69 & CD25: TableBaseline(Resting NK Cells)Activated NK CellsChangep-valueRaji Cell Lysis15.2%+/- 10.0%29.7% +/- 13.9%0.008CD69+ Expression5.9% +/- 2.9%42.6% +/- 12.5%0.008CD25+ Expression3.1% +/- 1.8%5.8% +/- 1.9%0.008 No infusional toxicity, adverse events attributed to NK therapy, GvHD nor deaths have been reported. As expected, all patients experienced transient myelosuppression (approx. 2 weeks). 3 patients suffered early relapse post-treatment (2 in cohort 1, 1 in cohort 2; average time to relapse from CR1 for these 3 patients was 104 days). In 5 of 7 evaluable patients, persistence of donor activated NK cells was observed from Day +7 post-infusion (chimerism = 1%-84%) to as late as day +56 in one patient. Flow cytometric comparison of donor NK cells and patient NK cells in the same sample by selective gating on the mismatched HLA allele showed that circulating donor NK cells typically differed from recipient NK cell in higher expression of NKG2A (e.g. 63.5% vs 2.7%), CD57 (e.g. 80.5% vs 13.2%) and CD69 (e.g. 11.6% vs 2.52%) suggesting a more normal, mature and activated phenotype than the endogenous host NK population. Even after loss of circulating donor primed NK cells, 2 of the 3 patients tested showed persistence of low levels of activated autologous NK cells (~10-20% of circulating NK) exceeding the numbers circulating pre-CNDO-109 NK treatment, out to Day +56, suggesting that the therapy may induce endogenous NK activation to enhance the patients’ innate immunity to AML. CONCLUSIONS This establishes proof of concept that CNDO-109-NK can persist transiently in patients with lasting microchimerism for > 1 month and can induce activation of endogenous NK cells in patients treated without cytokine administration. To date 4 of the 7 patients enrolled remain relapse free (max. = 410 days post CR1 date). These results highlight the potential of CNDO-109-NK cells in the treatment of AML and other malignancies. Disclosures Miller: Coronado Biosciences: Consultancy. Hillman:Coronado Biosciences: Employment. Silver:Coronado Biosciences: Employment. Szarek:Coronado Biosciences: Consultancy. Lowdell:Coronado Biosciences: Consultancy, Patents & Royalties. Gorelik:Coronado Biosciences: Employment. Rowinsky:Coronado Biosciences: Equity Ownership, Membership on an entity's Board of Directors or advisory committees.

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Mihailovic, Natasa, Ulrike H. Grenzebach, Nicole Eter, and Ralph-Laurent Merté. "Application Possibilities of a New Preloaded Nasolacrimal Duct Intubation System." Klinische Monatsblätter für Augenheilkunde 238, no. 01 (January 2021): 48–54. http://dx.doi.org/10.1055/a-1274-0773.

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Abstract Introduction The LacriJet (FCI S. A. S. – France Chirurgie Instrumentation, Paris, France) represents a novel, simplified and preloaded system for monocanalicular or monocanaliculonasal nasolacrimal duct intubation. It is a further development of the Masterka and shall reduce the intubation time during the surgical procedure. The aim of the present study was to present first experiences with this system for different indications. Material and Methods All patients who underwent nasolacrimal duct intubation with the LacriJet at the University of Muenster Medical Center in the period from March to November 2019 were included. The postoperative outcome was evaluated 3 to 6 months later. Results In total, 12 nasolacrimal duct intubations with the LacriJet were performed at our center in the above-mentioned period. The main indication for intubation was congenital nasolacrimal duct obstruction (CNLDO). In addition, intubation was performed in cases with eye lid tumors involving the nasolacrimal duct, in a case of canalicular laceration and in a case of canaliculitis. In 3 cases, there was an early dislocation or a complete loss of intubation. Of these, 2 were cases with CNLDO and the third dislocation was due to manipulation by the patient. All in all, the functional results were satisfying. Summary The use of the LacriJet is highly suitable for the treatment of CNLDO, stenting in canalicular laceration or lid tumours involving the lacrimal drainage system. However, the known disadvantages of monocanalicular intubation (dislocation, early loss of intubation) also occur with this type of system and a system briefing seems useful. The LacriJet therefore represents a modern and simple method for nasolacrimal duct intubation and can be used for various indications.

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Isaza, Gloria, and Sourabh Arora. "Probing without Irrigation in Children with Congenital Nasolacrimal Duct Obstruction." Clinical & Investigative Medicine 36, no. 3 (June 1, 2013): 158. http://dx.doi.org/10.25011/cim.v36i3.19727.

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Purpose: The purpose of this study was to evaluate the results of probing, without fluorescein irrigation, as a primary treatment for epiphora and/or mucous discharge, secondary to congenital nasolacrimal duct obstruction (CNLDO) Methods: The medical records of nine-two children (127 eyes) with CNLDO who underwent a single probing without the use of fluorescein irrigation between January 2006 and December 2011 were reviewed retrospectively. Inclusion criteria were no prior nasolacrimal surgical procedure, history of epiphora and/or discharge since birth or shortly after birth in one or both eyes and at least one of the following clinical signs: epiphora, muco-purulent discharge and increased tear meniscus height. Children were investigated in two sub-groups based on age at time of probing; group 1 (51 eyes/40 children) included children who underwent probing at age ≤ 2 years and group 2 (76 eyes/52 children) included children who underwent probing at age > 2years. The primary outcome was the complete disappearance of symptoms and signs in the affected eye(s), assessed at 3 months after surgery. Results: The success rate for the overall sample was 83.5 % (106/127 eyes), in group 1 was 90.2% (46/51) and in group 2 was 78.9% (60/76). There was no significant difference in success rate between groups (p=0.094). Gender (p=0.292), affected eye (p=0.647) and bilateral cases (p=0.739) were not associated with successful elimination of symptoms. Conclusion: Probing without fluorescein irrigation for CNLDO beyond 1 year of age is highly successful and comparable to the published efficacy rates of the traditional probing with fluorescein irrigation.

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Chunxiao, Guo, and Gao Zhiming. "RESTRICTED SCF CNDO/2 METHOD." Acta Physico-Chimica Sinica 5, no. 04 (1989): 420–26. http://dx.doi.org/10.3866/pku.whxb19890409.

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Spurling, TH, and DA Winkler. "CNDO/2 Calculations for Organohalides." Australian Journal of Chemistry 39, no. 2 (1986): 233. http://dx.doi.org/10.1071/ch9860233.

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A CNDO/2 parameterization for performing semiempirical molecular orbital calculations for organic molecules containing bromine and iodine is presented; the results are superior to those from other parameterizations, and generally agree with ab initio calculations and experiment.

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32

Zwanziger, Heinz, and Joachim Reinhold. "Konvergenzprobleme bei CNDO/2-Rechnungen." Zeitschrift für Chemie 19, no. 10 (August 31, 2010): 390–91. http://dx.doi.org/10.1002/zfch.19790191027.

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Back, D. M., and P. L. Polavarapu. "CNDO Force constants for glucose." Journal of Computational Chemistry 8, no. 6 (September 1987): 772–77. http://dx.doi.org/10.1002/jcc.540080604.

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34

Papadopoulos, M. G., and J. Waite. "The Polarizability and Second Hyperpolarizability of the Phenyl Cation." Zeitschrift für Naturforschung A 40, no. 11 (November 1, 1985): 1140–42. http://dx.doi.org/10.1515/zna-1985-1111.

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The polarizability, α, and second hyperpolarizability, γ, of the phenyl cation are computed by employing the CHF-PT-EB-CNDO method. Variations of the properties induced by changes in the structure of the cation are discussed.

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35

Burda, Jaroslav, Michal Bureš, and Čestmír Černý. "The Effect of Cluster Size on the Characteristics of Chemisorption in the Model Growth of Silicon Crystals." Collection of Czechoslovak Chemical Communications 57, no. 2 (1992): 241–47. http://dx.doi.org/10.1135/cccc19920241.

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The optimum cluster model size for the simulation of silicon crystal growth was sought by using the semiempirical CNDO/2 method. The Si4H9 system emerged as a reasonable compromise between the convergence of results and computation demands.

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36

Waite, J., and M. G. Papadopoulos. "Calculation of the Polarisability and Second Hyperpolarisability of Ferrocene, Fe(C5H5)2, Using the Extended CHF-PT-EB-CNDO Method." Zeitschrift für Naturforschung A 42, no. 7 (July 1, 1987): 749–52. http://dx.doi.org/10.1515/zna-1987-0715.

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The polarisability and second hyperpolarisability of ferrocene have been calculated using the CHF -PT -EB -CNDO method, which has been extended for the study of compounds containing transition metal elements. The computed polarisability value is in good agreement with experiment.

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Mosshammer, Alden A., Stanley M. Burstein, and Agatharchides of Cnidos. "Agatharchides of Cnidos, on the Erythraean Sea." Journal of the American Oriental Society 112, no. 3 (July 1992): 500. http://dx.doi.org/10.2307/603096.

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38

Verot, S., and P. Battesti. "Étude par CNDO/2 des mouvements de rotation des unités moléculaires constituant le squelette des polymères du type: PEK, PEEK et PEEKK." Canadian Journal of Chemistry 73, no. 4 (April 1, 1995): 581–92. http://dx.doi.org/10.1139/v95-075.

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Diphenyl ether (DPE) and diphenyl ketone (DPK) are the molecular constituents of polymers such as PEK, poly(ether–ketone); PEEK, poly(ether–ether–ketone), and PEEKK, poly(ether–ether–ketone–ketone). A conformational analysis of DPE and DPK is examined by means of semiempirical calculations using CNDO/2 (Complete Neglect of Differential Overlap). The modelization is first run disregarding electronic interactions and steric effects, then introducing them in the calculations. We found that the absolute minimum energy conformer has torsional angles (θ1,θ2) = (30°,150°) for the DPE (with and without interactions) and (θ1,θ2) = (90°,90°) for the DPK (without interactions). Considering the polymer chains of PEK, PEEK, and PEEKK, the motion of DPE is expected to be easier than that of DPK in regions of local motions and for equivalent steric effects. Keywords: conformational analysis, diphenyl ether, diphenyl ketone, CNDO/2, rotational barriers.

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39

Al-Omar, Suliman Yousef, Naushad Ahmad, Ashfaq Ahmad, Manal A. Al-Fwuaires, and Manawwer Alam. "CeO2–NiO Nanoflakes: Assessment and Their Anticancer Activity with HepG2 and MCF7 Cancer Cells." Journal of Nanoscience and Nanotechnology 20, no. 10 (October 1, 2020): 6047–56. http://dx.doi.org/10.1166/jnn.2020.18560.

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The present study describes the synthesis of CeO2–CNiO nanoflakes (CeNiO–NFs) via solution process in a very short time span and it was utilized for to control the growth against liver and breast cancer cells. The processed nanocomposites were characterized with several instruments such as of their physicochemical characteristics such as XRD, FT-IR, TGA/DTG/DSC, DLS, BET, SEM-EDX, TEM and UV-visible spectrophotometer respectively. The acquired results are in full justification with the physical data and it suggests that the formed CeO2–CNiO nanocomposite is in nanoflakes shaped (~20–C25 nm). Moreover, anticancer activity of CeNiO–NFs was investigated through MTT and NRU assays for liver (HepG2) and breast (MCF7) cancer cells. The results demonstrated that it exhibited dose-dependent cytotoxic effects in the range of 1–C100 μg/mL and revealed a reduction in their cell viability in response from low and high concentration of CeNiO-NFs.

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Chmurzyński, Lech, Adam Liwo, and Anna Tempczyk. "Relationship between the Electronic Structure and Acidic-Basic Properties of 4-Substituted Pyridine N-Oxides." Zeitschrift für Naturforschung B 44, no. 10 (October 1, 1989): 1263–70. http://dx.doi.org/10.1515/znb-1989-1020.

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CNDO/2 and MNDO calculations on pyridine N-oxide (PyO), 4-nitro- (4 NO2PyO), 4-methyl-(4 PicO), 4-methoxy- (4 MeOPyO), and 4-N′,N′ -dimethylamine-pyridine N-oxide (4 N′,N′Me2PyO) and on their protonated forms have been carried out. Unknown geometries have been obtained by optimization of the MNDO energy. It has been shown that for 4 NO2PyO, 4 MeOPyO, and 4 N′,N′Me2PyO N-oxide oxygen protonated forms are much more energetically stable than the forms protonated on substituents. The calculated ionization potentials and dipole moments of the compounds studied are in good agreement with the experimental data. Both CNDO/2 and MNDO protonation energies correlate well with the experimental pKa values determined in four different solvents: acetonitrile, propylene carbonate, nitromethane, and water, the slopes being however much less than unity which indicates the important role of the solvation effect. Based on the parameters of the correlations obtained the protolytic and solvation properties of the solvents studied have been discussed.

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Giambiagi, Myriam S. de, Mario Giambiagi, and Aloysio Paiva de Figueiredo. "Revisiting Julg's Structural Approach to Aromaticity." Zeitschrift für Naturforschung A 56, no. 6-7 (July 1, 2001): 413–15. http://dx.doi.org/10.1515/zna-2001-0601.

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Abstract Julg's classical formula for aromaticity is updated so as to involve bond indices. A simple CNDO/2 calculation is shown to account satisfactorily for heterocyclic typical rings and other miscellaneous systems. Results are compared with a multicenter MO bond index recently introduced as an aromaticity measure.

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42

Çiftçi, F., A. Akman, M. Sönmez, M. Ünal, A. Güngör, and V. Yaylali. "Systematic, Combined Treatment Approach to Nasolacrimal Duct Obstruction in Different Age Groups." European Journal of Ophthalmology 10, no. 4 (January 2000): 324–29. http://dx.doi.org/10.1177/112067210001000409.

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PurposeTo report the outcome of a step-by-step treatment approach for congenital nasolacrimal duct obstruction (CNDO).MethodsThree-hundred and fifty eyes with CNDO were included in the study. A number of treatment methods were applied systematically until a successful outcome was achieved. Listed in order from simple to more complex, the following methods were used: conservative management (massage and topical antibiotics), high-pressure syringing, probing, and silicone intubation. Treatment efficacy was determined according to age (Group 1: 0–6 months, Group 2: 7–12 months, Group 3: 13–24 months, Group 4: 25–72 months) and success rates were compared.ResultsConservative management was applied only in children less than 1 year of age, and was successful in 91.8% of Group 1 and 60% of Group 2 eyes. The difference between these two success rates was significant (p = 0.003). High-pressure syringing was performed in children under 24 months of age, with success rates of 41.7% in Group 1, 33.3% in Group 2, and 12.5% in Group 3. The overall success rate for first probing in all groups was 76.1%, with a range of 69.4% to 80.9%. After second probing, the overall cure rate for the entire cohort was 88.0%, with a range of 74.9% to 94.8%. There was no real difference in probing cure rates relative to age (p > 0.05). Silicone intubation was indicated and performed in two eyes of Group 2 children, three eyes of Group 3, and nine eyes of Group 4. Two ducts in Group 4 eyes remained obstructed after silicone intubation.ConclusionsThe systematic treatment approach to CNDO, including conservative management and minimally invasive procedures such as high-pressure syringing, probing, and silicone intubation, is highly successful. In this study, the cure rate for this combined approach was 100% in youngsters under 2 years of age and 94.5% in children 2 to 6 years old.

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Waite, J., and M. G. Papadopoulos. "The effect of the water–cation interaction on the polarisability and second hyperpolarisability of hydrated Li+. A comparative study." Canadian Journal of Chemistry 66, no. 6 (June 1, 1988): 1440–44. http://dx.doi.org/10.1139/v88-232.

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The CHF-PT-EB-CNDO method has been used to compute the polarisability and second hyperpolarisability of the hydrated lithium cation with one and two hydration shells. The effect of the Li+… (H2O)n interaction on these properties is discussed and the main findings are confirmed in hydrated Na+, Be2+, and Al3+.

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Krechl, Jiří, Stanislav Böhm, and Josef Kuthan. "Electronic spectral properties of redox coenzyme pyrroloquinoline quinone: A CNDO-CI study." Collection of Czechoslovak Chemical Communications 54, no. 5 (1989): 1203–8. http://dx.doi.org/10.1135/cccc19891203.

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Electronic absorption spectra of coenzyme PQQ and its reduced form, PQQH2, were calculated by the CNDO/S-CI method. The use of 170 monoexcited configurations was found to be necessary in order to give the correct interpretation of observed UV absorption. Influence of the carboxylic group geometries on the spectra is discussed.

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Thémélis, Pétros, and Dominique Mulliez. "Un acte d'affranchissement inédit du Trésor de Cnide." Bulletin de correspondance hellénique 113, no. 1 (1989): 343–46. http://dx.doi.org/10.3406/bch.1989.4727.

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Mitkidou, Sophia, Julia Stephanidou-Stephanatou, Constantinos A. Tsoleridis, and Nicholas E. Alexandrou. "Beckmann rearrangement of (Z)- and (E)-oximes of 2-aryl-4,5,6,7-tetrahydro-6,6-dimethyl-2H-benzo[d][1,2,3]-triazol-4-ones and 4,5,6,7-tetrahydro-6,6-dimethylbenzo[c][1,2,5]oxadiazol-4-ones." Collection of Czechoslovak Chemical Communications 55, no. 1 (1990): 245–55. http://dx.doi.org/10.1135/cccc19900245.

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The synthesis and geometry of (Z)- and (E)-oximes, II and III, derivatives of tetrahydro-2H-benzo[d][1,2,3]triazoles and tetrahydrobenzo[c][1,2,5]oxadiazoles, was investigated. The possibility of structural assignments of II and III by Beckmann rearrangement was examined. Some CNDO/2 calculations were also carried out on the oximes II and III.

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Waite, J., and M. G. Papadopoulos. "Relationships of the Polarisability with the Number of Valence Electrons, the Total Energy and the Second Hyperpolarisability of Methylbenzenes." Zeitschrift für Naturforschung A 44, no. 6 (June 1, 1989): 591–93. http://dx.doi.org/10.1515/zna-1989-0617.

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The total energy and polarisability of 12 methylbenzenes have been computed by employing the CHF-PT-EB-CNDO method. The relationships between the normalized polarisability, the total energy, the second hyperpolarisability and the number of valence electrons of the studied compounds are discussed. Variations in the polarisation properties induced by structural changes are also commented upon.

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Figueroa, K., R. Peña, and M. M. Campos-Vallette. "Valence Force Constants of N-Benzylideneanilines." Zeitschrift für Naturforschung B 44, no. 8 (August 1, 1989): 923–27. http://dx.doi.org/10.1515/znb-1989-0811.

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Valence force constants for N-benzylideneaniline and for two p,p′-disubstituted derivatives were estimated by means of a point-charge model using CNDO data. A vibrational assignment of bands which are sensitive to the electron donor-acceptor characteristic of substituents is proposed. The conformational changes are interpreted in terms of an intramolecular energy transfer between substituents.

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Fleischhauer, J., A. Koslowski, B. Kramer, E. Zobel, G. Bringmann, K. P. Gulden, T. Ortmann, and B. Peter. "Messung und Berechnung der CD-Spektren der Biaryl-Alkaloide Ancistrocladein und Dioncophyllein A [1] / Detection and Calculation of the CD Spectra from the Biaryl Alkaloids Ancistrocladeine and Dioncophylleine A [1]." Zeitschrift für Naturforschung B 48, no. 2 (February 1, 1993): 140–48. http://dx.doi.org/10.1515/znb-1993-0204.

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AbstractThe circular dichroism (CD) of the biaryls ancistrocladeine and dioncophylleine A has been studied. The CNDO/S method in combination with a Boltzmann weighting o f different structures using AM 1 energies has been applied to reproduce the experimental CD spectra o f the two alkaloids with known absolute configuration at with those o f the exciton chirality method.

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RODRÍGUEZ, ESTEFANÍA, and PABL J. LÓPEZ-GONZÁLEZ. "New records of Antarctic and Sub-Antarctic sea anemones (Cnidaria, Anthozoa, Actiniaria and Corallimorpharia) from the Weddell Sea, Antarctic Peninsula, and Scotia Arc." Zootaxa 3624, no. 1 (March 11, 2013): 1–100. http://dx.doi.org/10.11646/zootaxa.3624.1.1.

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Abstract:

Herein we provide new records for 22 Antarctic species of sea anemone sensu lato (Anthozoa: Actiniaria and Corallimorpharia) from the Weddell Sea, Antarctic Peninsula, and the Scotia Sea. We provided short descriptions, images of the external morphology of preserved specimens (but also of living specimens in most cases), cnida data, and distribution maps for each studied species. New records are presented for nine species in the Weddell Sea and the geographic or bathymetric distributions for 19 of the 22 studied species are extended.

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Journal articles on the topic 'Cnido'

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