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1

Gu, Yong Jun, Jin Liang Huang, Li Hua Li, Qian Li, Wei Hu, and Xiao Wang. "Microwave Dielectric Properties of Low Temperature Fired CaO-Li2O-Sm2O3-TiO2 Ceramics with LBS Glass Addition." Applied Mechanics and Materials 148-149 (December 2011): 887–90. http://dx.doi.org/10.4028/www.scientific.net/amm.148-149.887.

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The sintering behavior and microwave dielectric properties of the 16CaO-9Li2O-12Sm2O3-63TiO2 (abbreviated CLST) ceramics doped by small amount of LBS (Li2O-B2O3-SiO2) glass were investigated in this paper. The adding of LBS glass improved the densification of the CLST ceramics and the sintering temperature of the CLST ceramics had been efficiently lowered to 1000°C. Especially, the 10wt.% LBS doped CLST sintered at 1000°C for 3h has optimum microwave dielectric properties of Kr=69, Q×f=2846GHz, and TCF=9.7ppm/°C, indicating that it could be a suitable candidate for LTCC applications.
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2

Yang, Liu Shuan, Xiao Wang, Jin Liang Huang, and Fei Long Li. "Effects of ZnO-Bi2O3-B2O3-SiO2 Glass Additive on Dielectric Properties of CaO-Li2O-Sm2O3-TiO2 Microwave Dielectric Ceramics." Advanced Materials Research 148-149 (October 2010): 1580–83. http://dx.doi.org/10.4028/www.scientific.net/amr.148-149.1580.

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The effects of ZnO-Bi2O3-B2O3-SiO2(ZBBS) glass addition on the sintering behavior, crystalline phase, microstructure and dielectric properties of 16CaO-9Li2O-12Sm2O3-63TiO2(CLST) ceramics were investigated. The results show that ZBBS glass can effectively decrease the sintering temperature of CLST ceramics to 1 000 °C by liquid phase sintering. With the increase of ZBBS content, the second phase,Sm2Ti2O7 is found and increase, which causes the dielectric constant and dielectric loss of CLST decrease. The temperature coefficient of the resonance frequency shifts to positive. The optimum dielectric properties of r = 71, Tan = 0.006, TCF= 5×10-6/°C were obtained in 10wt% LBS glass-doped CLST ceramics sintered at 1 000 °C for 3 h.
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3

Rose, Colin, Dan Bergsagel, Thibault Dufresne, Evi Unubreme, Tianyao Lyu, Philippe Duffour, and Julia Stegemann. "Cross-Laminated Secondary Timber: Experimental Testing and Modelling the Effect of Defects and Reduced Feedstock Properties." Sustainability 10, no. 11 (November 9, 2018): 4118. http://dx.doi.org/10.3390/su10114118.

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The construction industry creates significant volumes of waste timber, much of which has residual quality and value that dissipates in conventional waste management. This research explored the novel concept of reusing secondary timber as feedstock for cross-laminated timber (CLT). If cross-laminated secondary timber (CLST) can replace conventional CLT, structural steel and reinforced concrete in some applications, this constitutes upcycling to displace materials of greater environmental impacts. The fabrication process and mechanical properties of CLST were tested in small-scale laboratory experiments, which showed no significant difference between the compression stiffness and strength of CLST and a control. Finite element modelling suggested that typical minor defects in secondary timber have only a small effect on CLST panel stiffness in compression and bending. Mechanically Jointed Beams Theory calculations to examine the potential impacts of secondary timber ageing on CLST panels found that this has little effect on compression stiffness if only the crosswise lamellae are replaced. Since use of secondary timber to make CLST has a more significant effect on bending stiffness, effective combinations of primary and secondary timber and their appropriate structural applications are proposed. The article concludes with open research questions to advance this concept towards commercial application.
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Yang, Liu Shuan, Xiao Wang, Yu Bin Wang, Jin Liang Huang, and Fei Long Li. "Effect of Compound Additives of Li2O-B2O3-SiO2 Glass and LiF on the Properties of CaO-Li2O-Sm2O3-TiO2 Ceramics." Advanced Materials Research 284-286 (July 2011): 1349–52. http://dx.doi.org/10.4028/www.scientific.net/amr.284-286.1349.

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Using Li2O-B2O3-SiO2 (LBS) glass and LiF as a liquid phase sintering additive, the effects of it on the microstructure and properties of 16CaO-9Li2O-12Sm2O3-63TiO2(CLST)ceramics were investigated. The results indicated that the compound sintering aids of LBS glass and LiF reduced the sintering temperature of CLST from 1300 °C to 950°C. Compared with the sample doped single LBS glass, the optimum dielectric properties, Kr=81, Tanδ=0.0073 could be obtained when the CLST ceramic samples doped 3 wt% LBS glass and 0.25 wt% LiF were sintered at 950°C for 3 h.
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5

Ferreira, Bruno Naves, Emmanuel Dias de Sousa Lopes, Isadora Ferreira Henriques, Marina De Melo Reis, Amanda Morais de Pádua, Karina De Figueiredo, Fernanda Aparecida Lopes Magno, and Flávia Gomes de Melo Coelho. "Treinamento físico multimodal com dupla tarefa na doença de Alzheimer: efeito nas funções cognitivas e na força muscular." Brazilian Journal of Kinanthropometry and Human Performance 19, no. 5 (December 8, 2017): 575. http://dx.doi.org/10.5007/1980-0037.2017v19n5p575.

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The aim of this study was to evaluate the effects of dual task multimodal physical training (MPT) on the cognitive functions and muscle strength in older adults with Alzheimer’s disease. Participants were 19 subjects with AD in the mild and moderate stages, divided into training group (TG) and control group (CG). The TG performed dual task MPT for 12 weeks. Subjects were evaluated at the pre- and post-intervention moments. The Mini Mental State Examination (MMSE), Clock Drawing Test (CDT) and Frontal Assessment Battery (FAB) were used to assess cognition. For muscle strength, the Chair Lift and Sit Test (CLST) and Manual Grasp Force (MGF) were used. The Wilcoxon test was used to analyze pre and post intragroup moments. The TG showed a significant improvement in FAB and CLST (p≤0.05) and a tendency to improve the MMSE score (p≤0.08). The CG showed significant improvement in CLST (p≤0.05). Dual task MPT improves the frontal cognitive functions and lower limb muscle strength of older adults with AD.
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6

GU, YONGJUN, JINLIANG HUANG, DAOMING SUN, QIAN LI, XIAO WANG, and HUI XU. "EFFECTS OF V2O5 ADDITION ON MICROWAVE DIELECTRIC PROPERTIES OF 16CaO-9Li2O-12Sm2O3-63TiO2 CERAMICS." International Journal of Modern Physics B 23, no. 06n07 (March 20, 2009): 1021–27. http://dx.doi.org/10.1142/s0217979209060403.

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Effects of V 2 O 5 addition on the microwave dielectric properties of 16 CaO -9 Li 2 O -12 Sm 2 O 3-63 TiO 2 (abbreviated CLST) ceramics prepared by conventional mixed oxides method were investigated as a function of V 2 O 5 content and sintering temperature. All the specimens were sintered between 1100°C and 1250°C. The sintering temperature of the CLST ceramics was lowered by 100°C with V 2 O 5 addition. With the changing content of V 2 O 5, the dielectric constants lie between 88.6 and 108.2, while the Q × f values are between 3275 and 6573 GHz. Especially, the specimens doped by 0.75 wt% V 2 O 5 sintered at 1200°C and 1250°C for 3 h show good microwave dielectric properties with Kr =100.4-108.2, Q × f >4500 GHz , and TCF=7-8 ppm/°C. Obviously, V 2 O 5 could be used as a suitable sintering aid that could improve densification and microwave dielectric properties of the CLST ceramics.
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7

Zheng, Liu, Jing Zhou, Jie Shen, Yanyuan Qi, Sheng Li, and Shirley Shen. "TEOS surface modification of CLST ceramic particles for PTFE-based composites." Journal of Materials Science: Materials in Electronics 29, no. 20 (August 3, 2018): 17195–200. http://dx.doi.org/10.1007/s10854-018-9811-8.

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Zheng, Liu, Jing Zhou, Jie Shen, Wen Chen, Yanyuan Qi, Shirley Shen, and Sheng Li. "The dielectric properties and dielectric mechanism of perovskite ceramic CLST/PTFE composites." Journal of Materials Science: Materials in Electronics 28, no. 16 (May 2, 2017): 11665–70. http://dx.doi.org/10.1007/s10854-017-6969-4.

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9

Zawisławska, Magdalena Anna. "SYNAMET - A Microcorpus of Synesthetic Metaphors. Preliminary Premises of the Description of Metaphor in Discourse." Cognitive Studies | Études cognitives, no. 16 (December 31, 2016): 107–18. http://dx.doi.org/10.11649/cs.2016.010.

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SYNAMET - A Microcorpus of Synesthetic Metaphors. Preliminary Premises of the Description of Metaphor in DiscourseThis article describes the preliminary premises of metaphor annotation in SYNAMET - the developing microcorpus of synesthetic metaphors. The analysis is based on the CLST theory (Context-Limited Simulation Theory) put forward by D. Ritchie. According to this theory, the metaphor’s vehicle may activate various types of associations between words: semantic relations, perceptual sensations, or emotional simulations. The range of potential associations evoked by the vehicle is limited by the topic, i.e. the lexical context in which the metaphor appears. The relations between the vehicle and the topic may be presented in the form of a semantic frame.To reconstruct the frames within the project, linguistic works devoted to sensory perception- vision, hearing, smell and taste- will be utilized. The corpus annotation will consist of the following stages: 1) metaphor identification, 2) indication of the metaphor cluster (CM) - a phrase or a passage of the text, centered around one referent, 3) isolation of the metaphorical units (MU) - word forms or phrases combining lexemes primarily belonging to different perceptual frames.The outcome of the MU analysis will include: a general metaphorical scheme of the MU, lexical items activating the frame of the MU (together with their grammatical description), a detailed metaphor scheme of the MU, and the semantic and grammatical categorization of the MU. SYNAMET – mikrokorpus metafor synestezyjnych. Wstępne założenia opisu metafory w dyskursieArtykuł opisuje wstępne założenia anotacji metafor w powstającym mikrokorpusie metafor synestezyjnych SYNAMET. Podstawą metody opisu będzie teoria CLST (Context-Limited Simulation Theory) D. Ritchie’go. W myśl tej teorii nośnik metafory (vehicle) może aktywować różne typy powiązania między wyrazami: semantyczne, zmysłowe lub emocjonalne. Potencjalny zakres powiązań nośnika ogranicza topik (topic), czyli kontekst, w którym metafora się pojawia. Powiązania nośnika oraz topiku przedstawia się w postaci ram interpretacyjnych.W rekonstrukcji ram na potrzeby korpusu wykorzystane zostaną prace językoznawcze poświęcone percepcji zmysłowej: wzrokowi, słuchowi, zapachowi, smakowi. Anotacja korpusu będzie przebiegać według następującego schematu: 1) identyfikacja metafor, 2) wyodrębnienie w tekście układu metaforycznego (UM) – frazy lub fragmentu tekstu, zorganizowanego wokół jednego referenta, 3) wyodrębnienie jednostek metaforycznych (JM) – form wyrazowych lub fraz, w których występuje połączenie leksemów przynależnych prymarnie do różnych ram percepcyjnych.Wyniki analizy JM zostaną przestawione w postaci: ogólnego schematu metaforycznego, zestawu wyrazów aktywujących ramy (wraz z ich opisem gramatycznym), szczegółowego schematu metaforycznego, kategoryzacji semantycznej i gramatycznej metafor.
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10

Zheng, Liu, Jing Zhou, Jie Shen, Yanyuan Qi, and Wen Chen. "Effects on the thermal expansion coefficient and dielectric properties of CLST/PTFE filled with modified glass fiber as microwave material." Chinese Chemical Letters 30, no. 5 (May 2019): 1111–14. http://dx.doi.org/10.1016/j.cclet.2018.12.026.

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11

Nguyen, April, Vinathi Polamraju, Truc T. Tran, Diana Panesso-Botero, Ayesha Khan, Eugenia Mileykovskaya, Heidi Vitrac, and Cesar A. Arias. "1446. Dynamics of Enterococcus faecalis Cardiolipin Synthase Gene Expression Reveal Compensatory Roles in Daptomycin Resistance." Open Forum Infectious Diseases 7, Supplement_1 (October 1, 2020): S726. http://dx.doi.org/10.1093/ofid/ofaa439.1627.

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Abstract Background Daptomycin (DAP) is a lipopeptide antibiotic targeting membrane anionic phospholipids (APLs) at the division septum, and resistance (DAP-R) has been linked to mutations in genes encoding i) the LiaFSR stress response system or its effector LiaX, and ii) cardiolipin synthase (Cls). Activation of the E. faecalis (Efs) LiaFSR response is associated with DAP-R and redistribution of APL microdomains away from the septum, and cardiolipin is predicted to be a major component of these APL microdomains. Efs harbors two putative cls genes, cls1 and cls2. While changes in Cls1 have been implicated in DAP-R, the exact roles of each enzyme in resistance are unknown. We aim to characterize the contributions of Cls1 and Cls2 in the development of DAP-R. Methods cls1 and cls2 were deleted individually and in tandem from DAP-S Efs OG117 and DAP-R Efs OG117∆liaX (a DAP-R derivative strain with an activated LiaFSR response). Mutants were characterized by DAP minimum inhibitory concentration (MIC) using E-test on Mueller-Hinton II agar and localization of APL microdomains with 10-N-nonyl-acridine orange staining. Quantitative PCR (qRT-PCR) was used to study gene expression profiles of cls1 and cls2 in Efs OG117∆liaX relative to Efs OG117 across the cell growth cycle. Results qRT-PCR revealed differential expression profiles of cls1 and cls2 associated with DAP-R. cls1 was highly upregulated in stationary phase concurrent with a decrease in cls2 expression. However, independent deletion of cls1 or cls2 in the DAP-R background resulted in no significant changes in DAP MICs or localization of APL microdomains (remaining non-septal). Further studies revealed that cls2 expression is upregulated upon deletion of cls1 in both the DAP-S and DAP-R background, suggesting a potential compensatory role for Cls2. Double deletion of both cls genes in the DAP-R strain decreased DAP MIC and restored the septal localization of APL microdomains. Conclusion Cls1 is the major and predominant enzyme involved in cell membrane adaptation associated with the development of DAP-R in E. faecalis. However, we describe a novel compensatory and overlapping role for cardiolipin synthases to ensure bacterial survival upon attack from antimicrobial peptides and related antibiotics. Disclosures Cesar A. Arias, MD, MSc, PhD, FIDSA, Entasis Therapeutics (Scientific Research Study Investigator)MeMed (Scientific Research Study Investigator)Merck (Grant/Research Support)
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12

Douglass, Martin V., François Cléon, and M. Stephen Trent. "Cardiolipin aids in lipopolysaccharide transport to the gram-negative outer membrane." Proceedings of the National Academy of Sciences 118, no. 15 (April 8, 2021): e2018329118. http://dx.doi.org/10.1073/pnas.2018329118.

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In Escherichia coli, cardiolipin (CL) is the least abundant of the three major glycerophospholipids in the gram-negative cell envelope. However, E. coli harbors three distinct enzymes that synthesize CL: ClsA, ClsB, and ClsC. This redundancy suggests that CL is essential for bacterial fitness, yet CL-deficient bacteria are viable. Although multiple CL–protein interactions have been identified, the role of CL still remains unclear. To identify genes that impact fitness in the absence of CL, we analyzed high-density transposon (Tn) mutant libraries in combinatorial CL synthase mutant backgrounds. We found LpxM, which is the last enzyme in lipid A biosynthesis, the membrane anchor of lipopolysaccharide (LPS), to be critical for viability in the absence of clsA. Here, we demonstrate that CL produced by ClsA enhances LPS transport. Suppressors of clsA and lpxM essentiality were identified in msbA, a gene that encodes the indispensable LPS ABC transporter. Depletion of ClsA in ∆lpxM mutants increased accumulation of LPS in the inner membrane, demonstrating that the synthetic lethal phenotype arises from improper LPS transport. Additionally, overexpression of ClsA alleviated ΔlpxM defects associated with impaired outer membrane asymmetry. Mutations that lower LPS levels, such as a YejM truncation or alteration in the fatty acid pool, were sufficient in overcoming the synthetically lethal ΔclsA ΔlpxM phenotype. Our results support a model in which CL aids in the transportation of LPS, a unique glycolipid, and adds to the growing repertoire of CL–protein interactions important for bacterial transport systems.
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13

Gunther, A., M. Kalinowski, A. Elssner, and W. Seeger. "Clot-embedded natural surfactant: kinetics of fibrinolysis and surface activity." American Journal of Physiology-Lung Cellular and Molecular Physiology 267, no. 5 (November 1, 1994): L618—L624. http://dx.doi.org/10.1152/ajplung.1994.267.5.l618.

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Polymerization of fibrin in the presence of pulmonary surfactant was recently noted to induce incorporation of phospholipids into the insoluble clot material, thereby effecting severe loss of surface activity (W. Seeger, A. Elssner, A. Gunther, H.-J. Kramer, and H. O. Kalinowski. Am. J. Respir. Cell Mol. Biol. 9: 213'220, 1993). In the present study, we investigated the influence of such incorporation of calf lung surfactant extract (CLSE) on the enzymatic cleavage of the fibrin network with the use of plasmin, trypsin, or elastase. Employing a fibrin-plate assay, the proteolytic release of radioactivity originating from 125I-labeled fibrinogen was assessed, and the pattern of split products was characterized by sodium dodecyl sulfate-polyacrylamide gel electrophoresis technique. Surface activity of CLSE was measured in the pulsating bubble surfactometer. When incorporated into the fibrin clot, CLSE inhibited the cleavage of fibrin by all proteases in a dose-dependent manner without affecting the profile of scission products. Inhibition of plasmin-induced clot lysis was also noted on incorporation of CLSE into clotted plasma and on incorporation of dipalmitoylphosphatidylcholine into fibrin polymers. In contrast, corresponding concentrations of CLSE added to the incubation medium after preformation of the fibrin matrix did not substantially influence the kinetics of fibrinolysis. CLSE incorporation into the nascent fibrin clot resulted in complete loss of surface activity, but adsorption and surface tension-lowering properties were largely restored by subsequent plasmic clot lysis. Arising fibrin split products were shown to display similar inhibitory strength on CLSE surface activity compared with fibrinogen split products.(ABSTRACT TRUNCATED AT 250 WORDS
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14

Nguyen, April, Truc T. Tran, Diana Panesso, Ayesha Khan, Eugenia Mileykovskaya, Heidi Vitrac, and Cesar A. Arias. "602. Mechanism of LiaY-Mediated Daptomycin Resistance in Enterococcus faecalis." Open Forum Infectious Diseases 6, Supplement_2 (October 2019): S282. http://dx.doi.org/10.1093/ofid/ofz360.671.

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Abstract Background Daptomycin (DAP) is a lipopeptide antibiotic that targets the cell membrane (CM) at the division septum. DAP resistance (DAP-R) in E. faecalis (Efs) has been linked to mutations in genes encoding the LiaFSR stress response system and lipid biosynthetic enzymes, including cardiolipin synthase (Cls). The signature phenotype of DAP-R is redistribution of CM anionic phospholipid (APL) microdomains. Using a genetic approach, we have identified a transmembrane protein (LiaY) as a major mediator of cell membrane APL redistribution associated with DAP-R. Here, we explore the mechanism of LiaY-mediated changes in the CM under the hypothesis that CM remodeling occurs through interactions with Cls. Methods Efs encodes two cls genes (cls1 and cls2). Deletion mutants of both cls genes were generated using the Crispr/cas9 system in the daptomycin-sensitive strain Efs OG117 and Efs OG117∆liaX (a DAP-R derivative of OG117). DAP minimum inhibitory concentration (MIC) was determined using E-test on Mueller–Hinton II agar. Visualization of APL microdomains was performed by staining mid-logarithmic phase cells with 1 µM of 10-N-nonyl-acridine orange (NAO) and fluorescence microscopy. Bacterial two-hybrid system was used to study interactions between LiaY with Cls1 or Cls2. Results Single or double deletion of cls1 or cls2 in Efs OG117 did not affect DAP MIC, and no changes in CM architecture were seen by NAO staining. In contrast,deletion of cls1 (alone or in conjunction with a deletion of cls2) in a DAP-R derivative of OG117 OG117∆liaX, resulted in a marked decrease in DAP MIC, and NAO staining of Efs OG117∆liaX∆cls1∆cls2 shows a restoration of septal APL microdomain localization.In the same DAP-R background, deletion of cls2 alone did not have any effect on DAP MIC or APL microdomain distribution. Additionally, bacterial two-hybrid assays showed a positive interaction of LiaY with Cls1 but not with Cls2. Conclusion We have identified the biochemical basis for DAP-R associated CM remodeling. In a proposed model, the LiaR-mediated activation of the LiaY triggers specific interactions with Cls1 displacing the protein away from the septum, resulting in local generation of APL microdomains that prevents DAP-mediated damage to the CM. Disclosures All authors: No reported disclosures.
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15

Korolova, D. S., Y. M. Stohnii, V. I. Gryshchuk, S. I. Zhuk, I. V. Us, T. M. Chernyshenko, O. P. Kostiuchenko, et al. "Thromboelastographic study of fibrin clot and molecular basis of maximum clot firmness." Ukrainian Biochemical Journal 93, no. 2 (May 20, 2021): 62–70. http://dx.doi.org/10.15407/ubj93.02.062.

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Ohniwa, Ryosuke L., Kana Kitabayashi, and Kazuya Morikawa. "Alternative cardiolipin synthase Cls1 compensates for stalled Cls2 function inStaphylococcus aureusunder conditions of acute acid stress." FEMS Microbiology Letters 338, no. 2 (November 22, 2012): 141–46. http://dx.doi.org/10.1111/1574-6968.12037.

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17

Schutt, K. M., H. M. Burrow, J. M. Thompson, and B. M. Bindon. "Brahman and Brahman crossbred cattle grown on pasture and in feedlots in subtropical and temperate Australia. 2. Meat quality and palatability." Animal Production Science 49, no. 6 (2009): 439. http://dx.doi.org/10.1071/ea08082.

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Market demand for a reliable supply of beef of consistently high eating quality led the Cooperative Research Centre for Cattle and Beef Industry (Meat Quality) to initiate a crossbreeding progeny test program to quantify objective and sensory meat quality differences between straightbred and first-cross Brahman cattle. Brahman, Belmont Red, Santa Gertrudis, Angus, Hereford, Shorthorn, Charolais and Limousin sires were mated to Brahman females over 3 years to produce 1346 steers and heifers in subtropical northern Australia. Calves were assigned within sire by age and weight to one of three market endpoints (domestic, Korean or Japanese), one of two finishing environments (subtropical or temperate) and one of two finishing diets (pasture or feedlot). Average carcass weights were 227, 288 and 327 kg for domestic, Korean and Japanese markets respectively. Only steers were finished for the Japanese market. The effects of sire breed, finishing regime, market endpoint and sex on sensory meat quality of four attributes score (CMQ4), ossification score and Warner-Bratzler shear force (SF), instron compression (IC), ultimate pH and percent cooking loss (CL) on the M. longissimus thoracis et lumborum (LT) and M. semitendinosus (ST) were determined. Straightbred Brahmans had the highest SFLT (5.39 ± 0.07; P < 0.001), ICLT (1.89 ± 0.02; P < 0.05) and CL in both muscles (P < 0.05). Straightbred Brahmans were the only genotype that failed to meet minimum CMQ4 grading standards (38.3; P < 0.001). Progeny with up to 75% Brahman content successfully met minimum objective and sensory meat quality consumer thresholds for tenderness (IC <2.2 kg, SF <5.0 kg; CMQ4 >46.5). There was little difference between crossbred progeny for most meat quality traits. All feedlot-finished animals were slaughtered at domestic, Korean and Japanese market weights by 24 months of age, with minimal differences in objective measures of meat quality between markets. The IC measures for all sire breeds were below 2.2 kg, indicating connective tissue toughness was not an important market consideration in feedlot-finished animals slaughtered by 24 months of age. Pasture finishing adversely affected all meat quality traits (P < 0.001) except CLST, with Korean and Japanese market animals having unacceptably tough SF, IC and CMQ4 measures. This was attributed to their older age at slaughter (31 and 36 months respectively), resulting from their seasonally interrupted growth path. While domestic animals slaughtered at 25 months of age off pasture had unacceptably high SF and IC, CMQ4 was acceptable. Subtropical feedlot animals had slightly more desirable (n.s.) SF and IC relative to temperate feedlot animals, whereas temperate feedlot animals had higher CMQ4 (P < 0.001). Genotype × environment interactions were not important.
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Wanderer, Jonathan P., and Naveen Nathan. "To Clot or Not to Clot." Anesthesia & Analgesia 126, no. 1 (January 2018): 2. http://dx.doi.org/10.1213/ane.0000000000002686.

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MILLER, JULIE. "To clot or not to clot…" Nursing Made Incredibly Easy! 3, no. 6 (November 2005): 4–7. http://dx.doi.org/10.1097/00152258-200511000-00001.

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Tanksley, Parris, Eric Chang, Iheoma Alinnor, Temidayo Abe, Anyanwoke Chisom, Benjamin Wibonele, Chima Odinkemere, and Melvin Crawford. "TO CLOT OR NOT TO CLOT." Chest 156, no. 4 (October 2019): A1439—A1440. http://dx.doi.org/10.1016/j.chest.2019.08.1281.

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Creel, Bradley, Anil Minocha, Amy Lobrano, Thomas Abell, and William Johnson. "To Clot or Not To Clot." American Journal of Gastroenterology 101 (September 2006): S473. http://dx.doi.org/10.14309/00000434-200609001-01219.

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Bendorf, Oliver. "Boy Clit 2, and: Boy Clit 3." Cream City Review 39, no. 1-2 (2015): 168–69. http://dx.doi.org/10.1353/ccr.2015.0013.

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Hashmi, Faiz, and Ankush Thakur. "Bacterial Endotoxin Test by Gel-Clot Method." International Journal of Trend in Scientific Research and Development Volume-3, Issue-3 (April 30, 2019): 564–67. http://dx.doi.org/10.31142/ijtsrd22945.

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Traini, Tonino, Giovanna Murmura, Bruna Sinjari, Giorgio Perfetti, Antonio Scarano, Camillo D’Arcangelo, and Sergio Caputi. "The Surface Anodization of Titanium Dental Implants Improves Blood Clot Formation Followed by Osseointegration." Coatings 8, no. 7 (July 20, 2018): 252. http://dx.doi.org/10.3390/coatings8070252.

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The anodization of titanium dental implant influences the biologic processes of osseointegration. 34 grit-blasted and acid-etched titanium specimens were used to evaluate micro- and nano-roughness (Ra), contact angle (θ) and blood clot extension (bce). 17 samples were anodized (test) while the remaining were used as control. The bce, was measured using 10 µL of human blood left in contact with titanium for 5 min at room temperature. The micro- and nano-scale Ra were measured under CLSM and AFM, respectively, while the θ was analyzed using the sessile drop technique. The bone-implant contact (BIC) rate was measured on two narrow implants retrieved for fracture. bce was 42.5 (±22) for test and 26.6% (±13)% for control group (p = 0.049). The micro-Ra was 6.0 (±1.5) for the test and 5.8 (±1.8) µm for control group (p > 0.05). The θ was 98.5° (±18.7°) for test and 103° (±15.2°) for control group (p > 0.05). The nano-Ra was 286 (±40) for the test and 226 (±40) nm for control group (p < 0.05). The BIC rate was 52.5 (±2.1) for test and 34.5% (±2.1%) for control implant (p = 0.014). (Conclusions) The titanium anodized surface significantly increases blood clot retention, significantly increases nano-roughness, and favors osseointegration. When placing dental implants in poor bone quality sites or with immediate loading protocol anodized Ti6Al4V dental implants should be preferred.
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25

Diwan, Naazneen. "Clit Intact." Kohl: A Journal for Body and Gender Research 3, Winter (December 1, 2017): 239–42. http://dx.doi.org/10.36583/2017030213.

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26

Saxby, Stephen. "CLSR BRIEFING." Computer Law & Security Review 17, no. 2 (March 2001): 132–43. http://dx.doi.org/10.1016/s0267-3649(01)00217-5.

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27

Saxby, Stephen. "CLSR BRIEFING." Computer Law & Security Review 17, no. 3 (May 2001): 202–16. http://dx.doi.org/10.1016/s0267-3649(01)00322-3.

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28

Saxby, Stephen. "CLSR BRIEFING." Computer Law & Security Review 17, no. 5 (September 2001): 343–60. http://dx.doi.org/10.1016/s0267-3649(01)00514-3.

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29

Saxby, Stephen. "CLSR BRIEFING." Computer Law & Security Review 17, no. 6 (November 2001): 427–40. http://dx.doi.org/10.1016/s0267-3649(01)01120-7.

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30

Saxby, Stephen. "CLSR BRIEFING." Computer Law & Security Review 18, no. 3 (May 2002): 212–32. http://dx.doi.org/10.1016/s0267-3649(02)00519-8.

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31

Saxby, Stephen. "CLSR BRIEFING." Computer Law & Security Review 18, no. 4 (July 2002): 285–302. http://dx.doi.org/10.1016/s0267-3649(02)00719-7.

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32

Saxby, Stephen. "CLSR BRIEFING." Computer Law & Security Review 18, no. 5 (October 2002): 366–82. http://dx.doi.org/10.1016/s0267-3649(02)00922-6.

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33

Saxby, Stephen. "CLSR BRIEFING." Computer Law & Security Review 18, no. 6 (November 2002): 446–63. http://dx.doi.org/10.1016/s0267-3649(02)01122-6.

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34

Saxby, Stephen. "CLSR briefing." Computer Law & Security Review 19, no. 2 (March 2003): 146–64. http://dx.doi.org/10.1016/s0267-3649(03)00211-5.

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35

Saxby, Stephen. "CLSR briefing." Computer Law & Security Review 19, no. 3 (May 2003): 250–65. http://dx.doi.org/10.1016/s0267-3649(03)00313-3.

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36

Saxby, Stephen. "CLSR briefing." Computer Law & Security Review 19, no. 6 (December 2003): 500–517. http://dx.doi.org/10.1016/s0267-3649(03)00611-3.

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37

Brouwer, Patrick A., Waleed Brinjikji, and Simon F. De Meyer. "Clot Pathophysiology." Neuroimaging Clinics of North America 28, no. 4 (November 2018): 611–23. http://dx.doi.org/10.1016/j.nic.2018.06.005.

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38

RAIMER, FAITH, and MYRA THOMAS. "CLOT STOPPERS." Nursing 25, no. 3 (March 1995): 34–47. http://dx.doi.org/10.1097/00152193-199503000-00014.

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39

Tanaka, Kenichi A., John McNeil, and Ezeldeen Abuelkasem. "Clot Retraction." Anesthesia & Analgesia 128, no. 4 (April 2019): e53-e54. http://dx.doi.org/10.1213/ane.0000000000004030.

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40

&NA;. "CLOT DISSOLVER." Nursing 21, no. 10 (October 1991): 100. http://dx.doi.org/10.1097/00152193-199110000-00032.

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41

Erickson, Deborah. "Clot Spotter." Scientific American 264, no. 6 (June 1991): 118–19. http://dx.doi.org/10.1038/scientificamerican0691-118a.

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42

Saxby, Stephen. "CLSR BRIEFING." Computer Law & Security Review 17, no. 4 (July 2001): 272–88. http://dx.doi.org/10.1016/s0267-3649(01)00719-1.

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43

Saxby, Stephen. "CLSR BRIEFING." Computer Law & Security Review 18, no. 2 (March 2002): 134–51. http://dx.doi.org/10.1016/s0267-3649(02)03020-0.

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44

Van Epps, Heather L. "Clot control." Journal of Experimental Medicine 203, no. 3 (March 13, 2006): 484. http://dx.doi.org/10.1084/jem.2033iti6.

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45

Dolan, Darrach. "Clot Blockers." Neurology Now 11, no. 5 (2015): 64–67. http://dx.doi.org/10.1097/01.nnn.0000472914.28287.59.

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46

Saxby, Stephen. "CLSR briefing." Computer Law & Security Review 6, no. 6 (March 1991): 41–47. http://dx.doi.org/10.1016/0267-3649(91)90187-z.

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47

Shehabeldine, Amr, Hany El-Hamshary, Mohamed Hasanin, Ayman El-Faham, and Mosaed Al-Sahly. "Enhancing the Antifungal Activity of Griseofulvin by Incorporation a Green Biopolymer-Based Nanocomposite." Polymers 13, no. 4 (February 12, 2021): 542. http://dx.doi.org/10.3390/polym13040542.

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Fungal biofilms have caused several medical problems, resulting in significant morbidity and mortality as well as poor response to antifungal drugs. The current study was designed to evaluate the enhancement of antifungal and anti-biofilm activity of Griseofulvin-loaded green nanocomposite-based biopolymers (Ge-Nco) of glycogen and gelatin against different strains of pathogenic Candida species. The prepared Ge-Nco was characterized using Fourier-transform infrared (FT-IR), X-ray diffraction pattern (XRD), scanning electron microscopy-energy dispersive X-ray (SEM-EDX) and transmission electron microscope (TEM). In addition, the morphology of the mature biofilm and the inhibition of biofilm was monitored and visualized using confocal laser scanning microscopy (CLSM). The minimal inhibitory concentrations (MIC) and (IC50) of Griseofulvin alone and the prepared Ge-Nco against three different strains of Candida sp. were determined according to Clinical and Laboratory Standards Institute (CLSI) method. The effects of Griseofulvin alone and Ge-Nco on the tested Candida sp. biofilm formation were determined by the crystal-violet staining protocol. The biofilm inhibition potential of Ge-Nco against the tested Candida sp. was detected and depicted under CLSM (2.5 D view). The findings depicted that Ge-Nco was prepared in nanometer size (10–23 nm). The observed minimum inhibitory concentration (MIC) of Griseofulvin alone and Ge-Nco against three different Candida sp. were found to be in range 49.9–99.8 μg/mL and 6.24–12.48 μg/mL, respectively. These results provide evidence for implementing efficient antivirulence approaches against three different Candida sp. that would be less likely to foster the emergence of resistance.
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Dressler, Diane K. "Death by Clot." AACN Advanced Critical Care 20, no. 2 (April 1, 2009): 166–76. http://dx.doi.org/10.4037/15597768-2009-2008.

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Blood clotting is a complex process that controls bleeding when tissues are injured. Unfortunately, this same process is capable of producing life-threatening thrombi in response to pathophysiological events. Blood clots may form in large and small vessels in response to triggers from disrupted vessel walls, inflammatory cells, cytokines, and other pathology. Platelet-rich clots can impair circulation to the myocardium and brain, leading to acute coronary syndromes and stroke. Erythrocyte-rich clots can embolize from the deep veins and threaten the lungs with pulmonary emboli. Microthrombi can block the circulation to tissues and organs in disseminated intravascular coagulation. An understanding of the pathogenesis of these various clotting syndromes directs effective intervention and preventive measures, minimizing the number of deaths by clot.
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Scodeller, Gabriela. "La CLASC/CLAT." European Review of Latin American and Caribbean Studies | Revista Europea de Estudios Latinoamericanos y del Caribe, no. 98 (April 7, 2015): 99. http://dx.doi.org/10.18352/erlacs.9984.

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Habibzadeh, Mohammad Reza, and Mohammad Reza Movahed. "A Runaway Clot." Acute Cardiac Care 13, no. 3 (April 25, 2011): 189. http://dx.doi.org/10.3109/17482941.2011.567278.

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