Academic literature on the topic 'Clostridioides difficile infection'

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Journal articles on the topic "Clostridioides difficile infection"

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Stewart, David B. "Clostridioides difficile Infection." Clinics in Colon and Rectal Surgery 33, no. 02 (February 25, 2020): 047–48. http://dx.doi.org/10.1055/s-0040-1701228.

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Hai, Zhao, Lei Peng Zhen, Ma Juan, Yang Fan, Cang Jin Rong, Liang Jing Yao, and Zhang Li Xia. "Extraintestinal Clostridioides difficile infection." IDCases 22 (2020): e00921. http://dx.doi.org/10.1016/j.idcr.2020.e00921.

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Guh, Alice Y., and Preeta K. Kutty. "Clostridioides difficile Infection (Japanese Version)." Annals of Internal Medicine 169, no. 7 (October 2, 2018): JITC49—JITC64. http://dx.doi.org/10.7326/istranslatedfrom_aitc201810020_japanese.

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Clarkin, Christina, Stephanie Quist, Renata Shamis, Amber E. King, and Bhavik M. Shah. "Management of Clostridioides difficile Infection." Critical Care Nurse 39, no. 5 (October 2019): e1-e12. http://dx.doi.org/10.4037/ccn2019841.

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Turner, Nicholas A., and Deverick J. Anderson. "Hospital Infection Control: Clostridioides difficile." Clinics in Colon and Rectal Surgery 33, no. 02 (February 25, 2020): 098–108. http://dx.doi.org/10.1055/s-0040-1701234.

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Abstract Clostridioides difficile remains a leading cause of healthcare-associated infection. Efforts at C. difficile prevention have been hampered by an increasingly complex understanding of transmission patterns and a high degree of heterogeneity among existing studies. Effective prevention of C. difficile infection requires multimodal interventions, including contact precautions, hand hygiene with soap and water, effective environmental cleaning, use of sporicidal cleaning agents, and antimicrobial stewardship. Roles for probiotics, avoidance of proton pump inhibitors, and isolation of asymptomatic carriers remain poorly defined.
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George Trad, Varun Sodhi, Matthew Brockway, Nazanin Sheikhan, Abdul Gader Gheriani, Olivia Astor, and Hatim Gemil. "Clostridioides (Clostridium) difficile infection: Review of literature." World Journal of Advanced Research and Reviews 14, no. 2 (May 30, 2022): 146–55. http://dx.doi.org/10.30574/wjarr.2022.14.2.0366.

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Clostridioides (Clostridium) difficile (C. difficile) is a gram-positive bacterium that infects the large intestine. The number of clostridium difficile infections has increased in the recent years due to multiple risk factors including frequent use of antibiotics and proton pump inhibitors. The virulence of C. difficile comes from its production of toxins. Treatment for C. difficile infection includes the use of antibiotics, monoclonal antibodies, or a fecal transplant.
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NIKOLAEVA, I. V., S. V. KHALIULLINA, G. Kh MURTAZINA, and V. A. ANOKHIN. "Clostridioides (Clostridium) difficile infection. Review of current clinical guidelines." Practical medicine 18, no. 6 (2020): 106–12. http://dx.doi.org/10.32000/2072-1757-2020-6-106-112.

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Clostridioides difficile (CDI) infection is a disease associated with a disruption of the gut microbiome with over-colonization of C. difficile, the toxins of which cause inflammation and damage to the colon. A dynamic assessment of the CDI prevalence indicates a significant increase in laboratory-confirmed cases of infection and a high mortality associated with it. C. difficile is recognized as the main causative agent of nosocomial infections in Europe, USA, Canada and Australia, which develops 48 hours after hospitalization in a medical facility and within 12 weeks after discharge. The severity of CDI is determined by the severity of infectious-toxic, diarrheal and abdominal syndromes. Severe CDI is characterized by manifestations of colitis, accompanied by severe leukocytosis, a decrease in albumin levels and an increase in serum creatinine levels. Development of fulminant forms, pseudomembranous colitis, toxic megacolon, intestinal perforation, sepsis is possible. The risk factors include in-hospital stay; recent use of antibiotics (within the previous 12 weeks, especially the use of fluoroquinolones, cephalosporins of III–IV generations, carbapenems and clindamycin), PPI and H2-histamine blockers; presence of inflammatory bowel diseases (ulcerative colitis, Crohn’s disease), immunodeficiency states, including iatrogenic; recent endoscopic examinations, surgical interventions on the gastrointestinal tract, tube feeding, enemas; possible contact with a family member who recently had a C..difficile infection. The «gold standard» for confirming the CDI diagnosis is the identification of the causative agent and/or toxins of C. difficile in the stool using specific laboratory research methods. Vancomycin or metronidazole are recommended as first-line therapy.
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Knežević, Darija, and Miroslav Petković. "Faecal transplantation and Clostridioides difficile infection." Scripta Medica 52, no. 3 (2021): 215–23. http://dx.doi.org/10.5937/scriptamed52-32752.

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Faecal microbiota transplantation (FMT), known equally well as faecal transplantation or faecal bacteriotherapy, is the process of implanting the faecal suspension containing balanced microbiota from a healthy donor to the colon of a recipient patient. Excessive growth of Clostridioides difficile (C difficile) in the intestinal microbiota resulting from antibiotic consumption is currently a rising threat to public health. FMT is one of the most important, newer approaches to treating C difficile infections. Since C difficile is regarded as an opportunistic bacterium triggering disease in conditions of disturbed homeostasis of the intestinal microbiota, restoration of healthy intestinal microflora facilitates suppression of toxic strain of C difficile by anaerobic bacteria of normal intestinal microflora with concomitant cure. Nurses have important role in caring for patients after faecal transplantation.
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Khanna, Sahil, and Ryan Pardi. "Clostridioides difficile infection: curbing a difficult menace." Therapeutic Advances in Gastroenterology 15 (January 2022): 175628482210899. http://dx.doi.org/10.1177/17562848221089906.

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Ohge, Hiroki, Toshiki Kajihara, and Hiroyuki Kitano. "V. Clostridioides Difficile Infection." Nihon Naika Gakkai Zasshi 107, no. 11 (November 10, 2018): 2261–68. http://dx.doi.org/10.2169/naika.107.2261.

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Dissertations / Theses on the topic "Clostridioides difficile infection"

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Orellana, Robert Charles. "Recurrent Clostridioides difficile infection: epidemiology and bedside scoring system analysis, 2014-2016." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1543505897011863.

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O'Grady, Keeley. "Genomic epidemiology of human Clostridioides (Clostridium) difficile infection in Australia, 2013-2018." Thesis, O'Grady, Keeley (2021) Genomic epidemiology of human Clostridioides (Clostridium) difficile infection in Australia, 2013-2018. Masters by Research thesis, Murdoch University, 2021. https://researchrepository.murdoch.edu.au/id/eprint/65186/.

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Clostridioides (Clostridium) difficile is an anaerobic pathogen found worldwide that is a leading cause of intestinal disease and prominent antimicrobial resistance (AMR) threat. Initially thought to be a hospital-acquired disease, it is increasingly being recognised in the community as well as in animal populations, with potential zoonotic transmission. Despite the high per-case burden C. difficile infection (CDI) places on healthcare systems and its potential as a reservoir of AMR genes for other pathogens, surveillance of resistance has been limited and inconsistent in Australia until recently. In Australia’s first longitudinal and nationwide surveillance study for CDI, the C. difficile Antimicrobial Resistance Surveillance (CDARS) study, collected ~500 clinical isolates of C. difficile from 10 healthcare facilities around Australia between 2013-2018. Whole-genome sequencing was performed to enable high-resolution genomic and phylogenetic analysis and develop a comprehensive understanding of the genomic epidemiology, transmission, evolution and pathogenic potential of C. difficile in Australia. This study found ~50% of samples contained three predominant PCR ribotypes (RTs): 014/020, 002 and 056. Core genome analysis determined that these RTs composed a genetically diverse group, with limited clonal relationships spread over large geographical areas, suggestive of widespread infection sources rather than transmission within the healthcare system. Binary toxin (CDT) genes were rare, with an A+B+CDT- toxin profile predominating. AMR was concentrated in multi-drug resistant RTs, with ~80% of all strains having no resistance determinants detected in silico. Resistance to macrolide lincosamide streptograminB (MLSB) and tetracycline class antimicrobials was most common, followed by aminoglycosides and fluoroquinolones, with rifamycin and other antimicrobial resistances rarely detected. Overall, C. difficile in Australia appears divided into an antimicrobial susceptible, binary toxin negative majority and a minority of multidrug-resistant strains with increased pathogenic potential.
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Kesler, Megan Kathleen. "Mitigation of Undesirable Flavor in Kefir Intended for Adjuvant Treatment of Clostridioides difficile Infection." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1565357220348372.

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Michel, Annika-Marisa [Verfasser], Dieter [Akademischer Betreuer] Jahn, and Michael [Akademischer Betreuer] Steinert. "Multiple molecular adaptation strategies of Clostridioides difficile to respond to various stresses in the gut environment during infection / Annika-Marisa Dorothee Michel ; Dieter Jahn, Michael Steinert." Braunschweig : Technische Universität Braunschweig, 2021. http://d-nb.info/1240382812/34.

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Smit, Nathiana [Verfasser], Dieter [Akademischer Betreuer] Jahn, and Till [Akademischer Betreuer] Strowig. "Mining the microbiome to modulate host defense against clostridioides difficile infections / Nathiana Smit ; Dieter Jahn, Till Strowig." Braunschweig : Technische Universität Braunschweig, 2020. http://d-nb.info/1221718185/34.

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Smit, Nathiana Verfasser], Dieter [Akademischer Betreuer] [Jahn, and Till [Akademischer Betreuer] Strowig. "Mining the microbiome to modulate host defense against clostridioides difficile infections / Nathiana Smit ; Dieter Jahn, Till Strowig." Braunschweig : Technische Universität Braunschweig, 2020. http://nbn-resolving.de/urn:nbn:de:gbv:084-2020111713119.

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Books on the topic "Clostridioides difficile infection"

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<em>Clostridioides difficile</em> Infection. MDPI, 2022. http://dx.doi.org/10.3390/books978-3-0365-3877-8.

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Meddings, Jennifer, Vineet Chopra, and Sanjay Saint. Preventing Hospital Infections. 2nd ed. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780197509159.001.0001.

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This book provides a detailed, step-by-step description of a model quality improvement intervention for hospitals, pinpointing the obstacles and showing how to surmount them. This second edition has been carefully updated, with new material describing some technical aspects of infection prevention, new tools for use by front-line providers, and results of recent large collaborative infection prevention studies. In easy-to-read, user-friendly language, it explains why clinicians neglect or actively oppose quality changes—from physicians who distrust change, to nurses who want to protect their turf, to infection preventionists who avoid the wards. The book also sheds light on how and why hospitals embark on quality improvements, the role of the hospital’s leadership cadre, the selection and training of the project team, and how to sustain quality gains long term. The intervention framework described in the book focuses on the prevention of hospital-associated infections—in particular, catheter-associated urinary tract infection (CAUTI)—but it is directly applicable to a variety of other hospital issues, such as falls, pressure sores, and Clostridioides difficile infection (CDI). In fact, the book includes a chapter applying this framework to a CDI prevention initiative. In addition, for hospitals having trouble with staff adherence to a quality initiative, we provide three infection-specific questionnaires (for CAUTI, CLABSI, and CDI) to help pinpoint individual problems, and provide a link to a website offering advice tailored to their specific circumstances.
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Sommermeyer, Henning, and Jacek Piątek. Clostridioides Difficile: Infections, Risk Factors, Prevention and Treatment. Springer International Publishing AG, 2021.

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Book chapters on the topic "Clostridioides difficile infection"

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Krishna, Amar, and Justin Oring. "Clostridium difficile (Clostridioides difficile) Infection Surveillance in Long-Term Care Facilities." In Clostridium Difficile Infection in Long-Term Care Facilities, 37–43. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-29772-5_4.

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Hussain, Syed Wasif, and Muhammad Salman Ashraf. "Epidemiology of Clostridioides difficile Infection in Long-Term Care Facilities." In Clostridium Difficile Infection in Long-Term Care Facilities, 7–23. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-29772-5_2.

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Kullar, Ravina, and Ellie J. C. Goldstein. "Role of Asymptomatic Carriers in Long-Term Care Facility Clostridioides (Clostridium) difficile Transmission." In Clostridium Difficile Infection in Long-Term Care Facilities, 25–36. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-29772-5_3.

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Krishna, Amar, and Teena Chopra. "Control of Clostridium (Clostridioides) difficile Infection in Long-Term Care Facilities/Nursing Homes." In Clostridium Difficile Infection in Long-Term Care Facilities, 53–64. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-29772-5_6.

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Petrov, Pavel, Stephen T. Rush, Shaun Pinder, Christine H. Lee, Peter T. Kim, and Giseon Heo. "Topological Data Analysis of Clostridioides difficile Infection and Fecal Microbiota Transplantation." In Emerging Topics in Statistics and Biostatistics, 427–46. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-42196-0_18.

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Romo, Jesús A., and Carol A. Kumamoto. "Characterization of the Effects of Candida Gastrointestinal Colonization on Clostridioides difficile Infection in a Murine Model." In Methods in Molecular Biology, 271–85. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2549-1_20.

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de Oliveira Ferreira, Eliane, and Gerly Anne de Castro Brito. "Clostridioides difficile." In Molecular Typing in Bacterial Infections, Volume II, 19–33. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-83217-9_2.

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Gronthoud, Firza Alexander. "Clostridioides difficile." In Practical Clinical Microbiology and Infectious Diseases, 397–400. First edition. | Boca Raton : CRC Press, 2020.: CRC Press, 2020. http://dx.doi.org/10.1201/9781315194080-5-9.

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Domachowske, Joseph, and Manika Suryadevara. "Clostridioides difficile Colitis." In Clinical Infectious Diseases Study Guide, 225–29. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-50873-9_37.

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Mileto, S., A. Das, and D. Lyras. "Enterotoxic Clostridia: Clostridioides difficile Infections." In Gram-Positive Pathogens, 991–1011. Washington, DC, USA: ASM Press, 2019. http://dx.doi.org/10.1128/9781683670131.ch61.

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Conference papers on the topic "Clostridioides difficile infection"

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Peric, A., V. Suljagic, B. Milenkovic, and S. Vezmar Kovacevic. "4CPS-243 Healthcare associated Clostridioides difficile infection in surgical and medical patients." In 25th Anniversary EAHP Congress, Hospital Pharmacy 5.0 – the future of patient care, 23–28 March 2021. British Medical Journal Publishing Group, 2021. http://dx.doi.org/10.1136/ejhpharm-2021-eahpconf.75.

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Monaghan, Tanya, Rima Biswas, Ashish Satav, Shrikant Ambalkar, Mark Wilcox, and Rajpal Singh Kashyap. "PTH-90 Prevalence of Clostridioides difficile infection in Central India: a prospective observational cohort study." In Abstracts of the BSG Annual Meeting, 8–12 November 2021. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2021. http://dx.doi.org/10.1136/gutjnl-2021-bsg.293.

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Monaghan, Tanya, Tahseen Jilani, Marcin Frankowski, Odette Pomenya, Tung On Yau, Niki Christodoulou, Maria Hatziapostolou, et al. "OTH-08 Circulating microRNAs linked to immunometabolic traits associate with faecal microbiota transplantation for clostridioides difficile infection." In British Society of Gastroenterology Annual Meeting, 17–20 June 2019, Abstracts. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2019. http://dx.doi.org/10.1136/gutjnl-2019-bsgabstracts.353.

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Monaghan, Tanya, Lindsey Russell, Elisa Rosati, Benjamin Mullish, Brandi Roach, Karen Wong, Gane Ka-Shu Wong, et al. "P307 FMT-associated alterations in the TCR repertoire of patients with severe or fulminant clostridioides difficile infection." In Abstracts of the BSG Campus, 21–29 January 2021. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2021. http://dx.doi.org/10.1136/gutjnl-2020-bsgcampus.381.

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Toja, F., P. Rodriguez Rodriguez, M. Sande Meijide, L. Canoura Fernández, MD Díaz López, A. Rodriguez Vazquez, and ME Gonzalez Pereira. "4CPS-210 Impact of the antibiotic therapy used during the SARS-CoV-2 pandemic on the incidence of Clostridioides difficile infection." In 26th EAHP Congress, Hospital pharmacists – changing roles in a changing world, 23–25 March 2022. British Medical Journal Publishing Group, 2022. http://dx.doi.org/10.1136/ejhpharm-2022-eahp.209.

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Lui, Rashid, Louis Lau, Ting-ting Chan, Sunny Wong, Kitty Cheung, Amy Li, ML Chin, et al. "IDDF2019-ABS-0191 Initial experience of faecal microbiota transplantation with frozen stools for the treatment of recurrent or refractory clostridioides difficile infection – a retrospective review from a quaternary referral centre in hong kong." In International Digestive Disease Forum (IDDF) 2019, Hong Kong, 8–9 June 2019. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2019. http://dx.doi.org/10.1136/gutjnl-2019-iddfabstracts.189.

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