Relevant bibliographies by topics / Clinical Neurology

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Clinical Neurology'

Author: Grafiati
Published: 4 June 2021
Last updated: 28 January 2023

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Journal articles on the topic "Clinical Neurology"

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Not Available, Not Available. "Manuale di Neurologia Clinica�[Manual of Clinical Neurology]." Neurological Sciences 21, no. 6 (December 1, 2000): 413. http://dx.doi.org/10.1007/s100720070059.

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Freedman, Daniel A., and Dara V. F. Albert. "Opinion and Special Articles: Neurology education at US osteopathic medical schools." Neurology 89, no. 24 (December 11, 2017): e282-e283. http://dx.doi.org/10.1212/wnl.0000000000004750.

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Osteopathic medical schools have a longstanding tradition of training primary care physicians (PCP). Neurologic symptoms are common in the PCP's office and there is an undersupply of neurologists in the United States. It is therefore crucial for osteopathic medical students to have a strong foundation in clinical neurology. Despite the importance, a mere 6% of osteopathic medical schools have required neurology clerkships. Furthermore, exposure to neurology in medical school through required clerkships has been correlated with matching into neurology residency. As osteopathic medical schools continue to expand, it will become increasingly important to emphasize the American Academy Neurology's published guidelines for a core clerkship curriculum. Practicing neurologists should take an active role in encouraging osteopathic medical schools to adopt these guidelines.
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Frey, Jessica, Brandon Neeley, Amna Umer, James W. Lewis, Anna Lama, Gauri Pawar, and Ann Murray. "Training in Neurology: Neuro Day." Neurology 96, no. 10 (March 8, 2021): e1482-e1486. http://dx.doi.org/10.1212/wnl.0000000000010859.

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ObjectiveTo determine whether increased patient interaction, exposure to the neurologic examination, and access to positive neurology mentors increase interest in neurology for first-year medical students.MethodsNeuro Day was a 2-part experience for first-year medical students. The first part consisted of a flipped classroom to teach the standard neurologic examination. The second part involved patient encounters modeled off of the traditional patient rounds. Students rotated from room to room, listening to patients' experiences with different neurologic diseases and eliciting pathologic neurologic examinations. Students were surveyed before and after Neuro Day.ResultsThe result of the binomial test indicated that the proportion of medical students interested in neurology significantly increased from 78% to 85% (95% confidence interval [CI] 0.79–0.92; p = 0.034) after participating in Neuro Day. The proportion of students' knowledge of clinical neurology increased from 45% to 63.1% (95% CI 0.54–0.72; p < 0.0001), comfort with performing a neurologic examination increased from 30% to 78.4% (95% CI 0.70–0.86; p < 0.0001), and fear of studying neurology decreased from 46% to 26% (95% CI 0.17–0.34; p < 0.0001) following Neuro Day. One hundred percent of students indicated that they would recommend Neuro Day to their peers.ConclusionNeuro Day is a feasible and effective model to incorporate into medical education. There was increased interest in and decreased fear of neurology. We anticipate that this paradigm can be used in the future to encourage students to consider a career in neurology.
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Moré, Jayaji M., Justin A. Miller, and Mill Etienne. "Disaster Neurology Update." Neurology: Clinical Practice 11, no. 2 (January 25, 2021): 175–78. http://dx.doi.org/10.1212/cpj.0000000000001042.

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In 2013, the term disaster neurology was introduced to describe a new practice opportunity for neurologists interested in providing needed, nonsurgical neurologic care in regions affected by natural or human-influenced disasters. Although previously presented as an option for interested neurologists, the coronavirus disease 2019 (COVID-19) pandemic has made it clear that every neurologist should be prepared to take on the unique challenges of disaster neurology. Examining the role of neurologists on the frontlines of the COVID-19 pandemic response represents an opportunity to review and apply key features of disaster neurology, including recognizing the categories of neurologic cases expected to be seen during a disaster, adapting inpatient and outpatient workflows, and accommodating the needs of vulnerable populations. Relating principles of disaster neurology to the response of neurologists to the current pandemic informs best practices for neurologic care as COVID-19 cases continue to surge throughout the United States and abroad.
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Pearce, J. "Clinical Neurology." Journal of Neurology, Neurosurgery & Psychiatry 53, no. 1 (January 1, 1990): 90–91. http://dx.doi.org/10.1136/jnnp.53.1.90-b.

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Geldmacher, MD, D. S. "Clinical Neurology." Neurology 40, no. 4 (April 1, 1990): 730. http://dx.doi.org/10.1212/wnl.40.4.730-d.

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Mumford, C. J. "CLINICAL NEUROLOGY." Brain 126, no. 5 (May 1, 2003): 1245–46. http://dx.doi.org/10.1093/brain/awg098.

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Schiffer, Randolph B. "Clinical Neurology." Journal of Neuropsychiatry and Clinical Neurosciences 1, no. 1 (February 1989): 84–86. http://dx.doi.org/10.1176/jnp.1.1.84.

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Schiffer, Randolph B. "Clinical Neurology." Journal of Neuropsychiatry and Clinical Neurosciences 1, no. 2 (May 1989): 213–14. http://dx.doi.org/10.1176/jnp.1.2.213.

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Schiffer, Randolph B. "Clinical Neurology." Journal of Neuropsychiatry and Clinical Neurosciences 1, no. 3 (August 1989): 329–30. http://dx.doi.org/10.1176/jnp.1.3.329.

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Dissertations / Theses on the topic "Clinical Neurology"

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Lindh, Jonas. "Cryptogenic Polyneuropathy : Clinical, Environmental, And Genetic Studies." Doctoral thesis, Linköpings universitet, Neurologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-71215.

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Objectives: The purpose of this medical thesis was to describe the clinical and neurophysiological features and to evaluate the health related quality of life (HR-QoL) in patients with cryptogenic polyneuropathy. We also wanted to investigate different occupational, and leisure time exposures as determinants for cryptogenic polyneuropathy, and to analyze whether polymorphisms for the null alleles of Glutathione S-Transferase Mu-1 (GSTM1), and Theta-1 (GSTT1), and a low activity genetic variation of epoxide hydrolase (EPHX) affect the risk of developing polyneuropathy. These genes were chosen because their enzymes are important in the metabolism of toxic compounds. Methods: The medical records of all patients aged 40–79 years with the diagnosis of cryptogenic polyneuropathy from 1993 to 2000 were analyzed, and data regarding clinical symptoms, laboratory findings, and neurophysiological findings at diagnosis were collected. 255 cases were found. When the medical records were reevaluated assessment to a protocol 168 patients remained as cryptogenic. Two validated instruments (SF-36 and EQ-5D) for measuring HR-QoL were sent to patients, and a reference group from the general population. Additional clinical information, and data on occupational, and leisure time exposure was obtained from postal questionnaires. Crude odds ratios (COR), and logistic regression odds ratios (LOR) were calculated for exposures with five or more exposed cases and referents taken together. We also tested for genetic polymorphisms of GSTM1 and GSTT1, and epoxide hydrolase exon three, EPHX*3. Results: 68% of the patients were men. The mean age at first symptom was 61 years and at diagnosis 64 years. Distal numbness was the most common symptom, but pain, pedal paresthesias, and impairment of balance were also common. The most common clinical findings were decreased or lost proprioception or sense of vibration (80%), and loss of ankle jerks (78%). Neurography showed mixed sensorimotor polyneuropathy of axonal or mixed axonal and demyelinating type. QOL was significantly affected concerning motor functions, with 42% of the patients reporting problems to walk, 3% having problems with daily activities, and 85% were suffering from pain. Mental health was preserved. Mobility was declining with increasing age, but was not affected by disease duration. Increased risks were found in men for occupational exposure to sulphur dioxide, xylene, methyl ethyl ketone, and herbicides and in women for occupational exposure to lead, nitrous oxide, and insecticides. Interaction between occupational and leisure time exposure were seen for several exposures. No significant correlation was found between GSTM1, GSTT1, and EPHX1 polymorphisms in patients with cryptogenic polyneuropathy compared with controls. A tendency, however, was seen for the GSTT1 null phenotype, which was enhanced among smokers compared to controls (OR 3.7). Conclusions: Cryptogenic polyneuropathy is a slowly progressive sensorimotor nerve lesion of mainly axonal type. Patients with cryptogenic polyneuropathy have a lower QOL compared to the general population, although mental health scores did not differ between the groups. Our results show that known determinants could be confirmed, but also some new appeared i.e. sulphur dioxide, hydrogen sulphide, fungicides, and vibrations in the feet. Moreover our results point to a synergistic effect of various exposures. Our hypothesis is that the GSTT1 null polymorphism may be related to an impaired metabolism of toxic substances and reactive oxygen that could lead to nerve damage in the peripheral nervous system. Our results are indicating that components in cigarette smoke might increase the risk of axonal neuropathy in genetically predisposed patients.
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Ferreira, Adriana Filipa da Silva. "Curricular training report: clinical trials coordination in neurology." Master's thesis, Universidade de Aveiro, 2015. http://hdl.handle.net/10773/21557.

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Mestrado em Biomedicina Farmacêutica
O presente relatório descreve as atividades desenvolvidas durante o estágio curricular como coordenadora de investigação clínica, que teve lugar na Unidade de Farmacologia Clínica do Instituto de Medicina Molecular e decorreu de Setembro de 2014 a Junho de 2015. A principal atividade desempenhada durante este estágio foi a coordenação de ensaios clínicos na área da neurologia, nomeadamente ensaios de fase II, III e IV. Foram desenvolvidas outras atividades, tais como gestão de dados clínicos, atividades de farmacovigilância e escrita científica e monitorização de estudos clínicos, com vista a complementar a formação curricular. Neste relatório é, também, apresentada uma breve contextualização do estado de arte do processo de Investigação & Desenvolvimento de novos medicamentos, tendências atuais e especificidades do desenvolvimento de medicamentos na área da neurologia. Para além disso são abordadas as dificuldades sentidas durante o estágio e as estratégias utilizadas para as ultrapassar, bem como a visão pessoal sobre o papel do coordenador de investigação clínica na condução de ensaios clínicos. Globalmente, a realização deste estágio curricular traduziu-se na oportunidade de aplicar e aprofundar os conhecimentos e competências adquiridos ao longo do percurso académico, em especial no Mestrado em Biomedicina Farmacêutica, e de desenvolver competências e aptidões, tanto a nível profissional como pessoal, fulcrais para um profissional de investigação clínica. Em conclusão, este estágio constituiu uma introdução à prática da investigação clínica.
This report describes the activities developed during the curricular training as coordinator of clinical research, which took place in the Unidade de Farmacologia Clínica of the Instituto de Medicina Molecular and was held from September 2014 to June 2015. The main activity performed during this training was the coordination of clinical trials in the field of neurology, mainly phase II, III and IV clinical trials. Other activities, such as data management, pharmacovigilance, medical writing and monitoring of clinical studies, were developed to complement the training. This report also presents a brief background of the state of the art of the Research & Development process of new drugs, current trends and specificities of the drug development in neurology. Furthermore, it addresses the difficulties experienced during the training and the strategies used to overcome them, as well as a personal insight on the role of the clinical research coordinator in conducting clinical trials. Overall, achieving this curricular training resulted in the opportunity to apply and deepen the knowledge and skills acquired throughout the academic career, especially in the Masters in Pharmaceutical Biomedicine, and to develop skills and abilities, at professional and personal level, central to a professional of clinical research. In conclusion, this training was an introduction to the practice of clinical research.
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Nygren, Ingela. "ALS - a clinical thesis /." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4804.

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Blanco, Núñez Igor D. "Diffuse optical monitoring of cerebral hemodynamics in experimental and clinical neurology." Doctoral thesis, Universitat Politècnica de Catalunya, 2015. http://hdl.handle.net/10803/285634.

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The study of the brain using diffuse optical methods has progressed rapidly in the recent years. The possibility of studying the cerebral microvasculature in addition to the portability and low cost of these devices, opens a new door in the study of the cerebral pathophysiologies. In this scenario, the study of the cerebral hemodynamics of ischemic patients might allow neurologists to improve the performance of the early medical treatments and therapies used up to date. In this thesis, I have conducted a pioneering study where cerebral autoregulation was studied in ischemic stroke patients during the early hours after the stroke. Similarly, some other diseases can provoke impaired cerebral autoregulation in the long term. One of them is the obstructive sleep apnoea (OSA) syndrome which can provoke a risk increase of developing cardiovascular diseases and ischemic stroke. In this regards, I have carried out the largest to date study conducted with Diffuse Correlation Spectroscopy in patients with OSA and I have compared their hemodynamical response to an orthostatic challenge test with a control group of healthy subjects. Finally, primary animal research is of great importance in the development of new therapies, medical strategies and in the validation of new drugs with the aim of reducing the high mortality and slow and costly recovery of ischemic patients. In consequence, many models of ischemia are reproduced in rodents where the cerebral hemodynamics are studied using expensive equipments such as MRI scanners or by techniques that involve invasive approaches like for instance removing the scalp or thinning the skull which in turn cause a worsening in the living conditions of the animal. In relation to this point, I have developed a fully non-invasive method to study the cerebral hemodynamics in rats that allows to proceed with longitudinal studies and which I hope will be useful in future biomedical research.
El estudio del cerebro mediante métodos de óptica difusa ha progresado rápidamente en los últimos años. La posibilidad de estudiar la microvasculatura cerebral junto con la portabilidad y bajo coste de estos equipos abre una ventana de posibilidades para el estudio de fisiopatologías cerebrales. En este escenario, el estudio de la hemodinámica cerebral en pacientes isquémicos podría permitir a los neurólogos mejorar el rendimiento de los tratamientos médicos tempranos y de las terapias utilizadas hasta la fecha. En esta tesis he realizado un estudio pionero al respecto, estudiando por primera vez la hemodinámica cerebral de pacientes isquémicos durante las primeras horas después del infarto cerebral. De igual manera, existen otro tipo de enfermedades que pueden desarrollar un empeoramiento a largo plazo de la autorregulación cerebral. Entre ellas destaca el síndrome de apnea obstructivo (SAO), debido al cual el empeoramiento de la hemodinámica cerebral provoca un aumento del riesgo directo de sufrir enfermedades cardiovasculares y un aumento del riesgo de infarto cerebral. Al respecto, he llevado a cabo el mayor estudio hasta la fecha con pacientes con SAO donde he estudiado su respuesta hemodinámica a un test ortostático comparado estos resultados con los obtenidos en grupo de control de pacientes sanos. Finalmente, la investigación primaria en animales es de vital importancia en el desarrollo de nuevas terapias y estrategias médicas así como en la validación de nuevos fármacos que reduzcan la alta mortalidad y la lenta y costosa recuperación de los pacientes isquémicos. En consecuencia, numerosos modelos de isquemia son reproducidos en roedores donde se estudia la hemodinámica cerebral mediante caros equipos como los resonadores magnéticos o mediante técnicas que implican someter al animal a cierta cirugía en la que se le sustrae el cuero cabelludo o se le lima el cráneo. En relación con esto último, he desarrollado un método completamente no invasivo para estudiar la hemodinámica cerebral en ratas y que permite llevar a cabo estudios longitudinales, el cual espero sea utilidad en futuras investigaciones biomédicas.
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Zuberi, Sameer Mustafa. "A clinical and genetic study of ion channel disorders in child neurology." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/29438.

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Ion channels are macromolecular proteins in cell membranes that control the passage of charged particles including sodium, potassium and calcium ions in and out of cells. Rapid electrical signalling in the nervous system is mediated through the passage of ions through these channels. It is therefore not surprising that genetic mutations in the genes coding for these channels can result in neurological disease. Ion channel disorders or channelopathies have emerged in the last ten to fifteen years as an important new way of understanding neurological disease. Many of these conditions are paroxysmal in nature and include generalised and focal epilepsies, movement disorders and neuromuscular disorders. Some of these conditions follow simple Mendelian inheritance and are rare forms of common disorders such as epilepsy but they provide a useful model for more common neurological diseases with complex inheritance. Some conditions such as Dravet syndrome, a severe infantile onset epilepsy and sodium channelopathy produce devastating consequences for the affected child. In this thesis I will describe the clinical work I have undertaken defining phenotypes of this emerging group of disorders. Detailed phenotyping is the first essential step in characterising new aspects of these genetic disorders. I have collaborated closely with molecular geneticists and cell physiologists in units around the world exchanging ideas in order to better understand the mechanisms of disease and hopefully translate this into better care for patients. The main themes covered in the thesis are episodic ataxias type 1 and 2 (EA1 & 2), benign familial neonatal convulsions, autosomal dominant nocturnal frontal lobe epilepsy, and Dravet syndrome and other SCN1A related epileptic encephalopathies. In the course of this work I have described novel relationships between EA1 and EA2 and epilepsy, described a novel gene and phenotypes associated with frontal lobe epilepsy, a novel presentation of a potassium channelopathy, a family with a new genetic mechanism for their neonatal convulsions and epilepsy, and children with a novel mechanism for Startle disease (hyperekplexia). I have demonstrated the clinical utility of this translational research by establishing a molecular genetic diagnostic service for sodium channel (SCN1A) related infantile epilepsies. A study of the results from this national UK service shows that genetic diagnosis allows early diagnosis of these epilepsies. This can result in earlier focused treatment, and the hope for better epilepsy control and developmental outcome. I discuss the implications of this work and ongoing and future research projects.
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Van, Coller Riaan. "A clinical, neurophysiological and genetic study of South African familial combined myoclonic syndromes." Thesis, University of Pretoria, 2021. http://hdl.handle.net/2263/78827.

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Myoclonus is a complex disorder of rapid repetitive muscle jerks that can occur in proximal or distal appendicular or axial muscles. It can be of cortical, sub-cortical or spinal cord origin; part of progressive and severely disabling epilepsy syndromes, basal ganglia conditions, and physiological or even functional (psychogenic)1. A systematic review of the literature shows the knowledge gap of the genetic causes of myoclonus in South Africa with 25 identified publications from Africa of which eleven were from South Africa. Publications varied from case studies to case series and included four publications with cortical myoclonic tremor (CMT) and two with North Sea Progressive Myoclonic Epilepsy, two with subcortical myoclonus and case studies with rare cases of individuals with myoclonic disorders. In this publication the study of myoclonus in three different settings is presented. In the first: cortical myoclonic tremor (CMT), a rapid distal form of myoclonus, resembling tremor, with neurophysiological evidence of cortical origin. The study researched a South African family with Familial Cortical Myoclonic Tremor with Epilepsy (FCMTE). The first part of this study showed the median onset of cortical tremor 16 was and that of epilepsy was 42 years; patients were stable with long term follow up after 30 years without evidence of progressive ataxia or cognitive impairment. The second part of the study presents the discovery of the genetic mutation causing this condition: a pentanucleotide repeat expansion in the intronic region of the STARD7 gene. This mutation was also found in families with FCMTE2 with a similar phenotype and followed on work showing pentanucleotide repeat expansion mutations in other forms of FCMTE in different genetic locations. The second setting proved a new mutation, a premature stop mutation p.L275X, in the epsilon-sarcoglycan gene causing subcortical origin, Myoclonus Dystonia Syndrome (MDS) in a three generation South African family with mild phenotype differences in the clinical presentation: myoclonus and dystonia in the same appendicular body part as well as truncal. Two of the affected individuals studied underwent Deep Brain Stimulation surgery of the Globus Pallidum with significant sustained improvement in the motor and non-motor features of MDS recorded and confirmed by a blinded rater. In the third setting, two patients with sporadic Paroxysmal Non-kinesigenic dyskinesia (PNKD) with the complex phenomenology of episodic dystonia, myoclonus and chorea of South African origin is presented. Both patients underwent successful DBS of the pallidum with long-term outcomes presented. Although these two individuals were not tested for the known myofibrillogenesis regulator-1 (MR-1) mutation they represent two cases of this rare disorder from South African setting and prove the successful use of DBS treatment.
Thesis (PhD)--University of Pretoria, 2021.
Neurology
PhD
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Lindström, Per. "Diabetic neuropathy : clinical and experimental studies /." Stockholm, 1997. http://diss.kib.ki.se/1997/19971003lind.

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Albernaz, Raquel Mincarelli [UNESP]. "Aspectos clínicos e radiográficos da coluna cervical de bezerros submetidos a Prova do Laço." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/89034.

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Made available in DSpace on 2014-06-11T19:23:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-07-27Bitstream added on 2014-06-13T20:30:35Z : No. of bitstreams: 1 albernaz_rm_me_jabo.pdf: 606225 bytes, checksum: fc8139f6f3b1c020259e97b3cecff7e3 (MD5)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
A modalidade de rodeio denominada Prova do Laço de Bezerro tem sido questionada sobre a ocorrência de possíveis lesões nas vértebras cervicais ocasionadas pela tração da corda no pescoço dos bezerros. Neste trabalho avaliou-se 15 bezerros mestiços, machos ou fêmeas, entre cinco e seis meses de idade experimentalmente submetidos a prova do laço. Os animais foram laçados três vezes por semana, em dias alternados, durante cinco semanas, somando o total geral de 225 laçadas. A prova experimental foi realizada de forma semelhante à prova oficial, pelo mesmo cavaleiro profissional da modalidade. Os bezerros foram avaliados mediante exame clínico geral e neurológico ao início da primeira, durante a terceira e ao término da quinta semana experimental. Radiografias simples e contrastadas das vértebras cervicais foram efetuadas ao início da primeira e ao término da quinta semana de experimento. Os métodos de laçadas foram acompanhados e classificados qualitativamente em fortes ou fracos. Não foram encontradas alterações clínicas e radiográficas nos animais durante o experimento. O rigor da laçada foi considerado forte em 77% dos casos. O fato de não terem sido encontradas alterações clínicas e radiográficas indicam que a ocorrência de lesões cervicais em bezerros submetidos a prova de laço não é tão alta como o propalado, entretanto, trata-se de procedimento rude e agressivo. Número mais expressivo de experimentos semelhantes a este deverá ser conduzido tanto sob condições controladas como em provas reais para confirmar os dados da presente pesquisa.
The modality of roundup Calf Roping has been questioned on the occurrence of possible injuries in the cervical vertebrae caused by the rope tension in calfs neck. In this work 15 calves, male or female, ages varying from five and six months experimentally submitted to calf roping were evaluated. The procedure was carried through three times per week, in alternated days, during five weeks, adding the total of 225 lassoed. The experimental test was carried through of similar form to the official test, for the same professional knight of the modality. The calves had been evaluated by means of general and neurological clinical examination to the beginning of the first one, during third and to the ending of the fifth experimental week. Simple and contrasted x-rays of the cervical vertebrae had been made to the beginning of the first one and the ending of the fifth week of experiment. The lassoed methods had been observed and classified qualitatively in weak or strong. Clinical and radiographic alterations in the animais during the experiment had not been found. The severity of the lassoed was considered strong in 77% of the cases. The fact not to have been found clinical and radiographic abnormalities indicates that the occurrence of cervical injuries in calves submitted to calf roping is not as high as divulged, however, is about aggressive and rude procedure. Similar experiments must be made in such a way to be lead under controlled conditions as in real tests to confirm the data of the present research.
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Al, Talalwah Waseem. "The vascular variability of the iliac system and clinical diagnosis in radiology and neurology." Thesis, University of Dundee, 2013. https://discovery.dundee.ac.uk/en/studentTheses/1aa955a0-1289-4670-b226-0eea5425ae0b.

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The sciatic nerve is the largest nerve in the human body giving both motor and sensory innervations to the lower limb. It can be affected in chronic diseases, such as diabetes, or compressed anatomically by structures such as piriformis and aneurysms leading to sciatica or paralysis of the lower limb. The current study therefore focuses on the arterial supply of the sciatic nerve as well as its course. Embryologically, the sciatic nerve is supplied via the axial artery during the first trimester. As the axial artery regresses, the iliac system develops. A failure of sciatic artery regression leads to several variations of pelvic and femoral arteries, with a risk of iatrogenic injury/trauma for those patients undergoing pelvic, gluteal and thigh surgical procedures. An understanding of the variability of the pelvic arteries in relation to a coexistent sciatic artery will provide an appropriate background for clinicians. The present study proposes a new theory of sciatic artery development and persistence, as well as new theories for the superior and inferior gluteal, internal pudendal and obturator arteries. The thesis is in two parts: first an anatomical study on the dissection of 171 cadavers including the pelvic, gluteal and thigh regions to observe (i) the patterns of the arteries these regions, and (ii) the course of the sciatic nerve. With variable course of sciatic nerve, there is a variability of its blood supply. Moreover, it includes a new classification of sciatic nerve with respect to clinical implications. The thesis clarifies the origins of the sciatic artery and its course. The second part is a literature review of sciatic artery aneurysm cases in 171 patients, which clarifies the risk of aneurysm, together with its incidence with respect to pathologic finding and associated disorders. Radiologists have to be aware of the internal iliac artery classifications to be able to alert general surgeons, orthopaedic surgeons, obstetricians, gynecologists, and urologists so that they can improve patient management.
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Quintas, Inês de Avelar Teixeira Califórnia. "Canine intracranial pachymeningeal enhancement : a study of 2 clinical cases." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2019. http://hdl.handle.net/10400.5/18989.

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Dissertação de Mestrado integrado em Medicina Veterinária
Post-contrast pachymeningeal enhancement, synonymous of post-contrast dural or dura-arachnoid enhancement, is an imaging feature best appreciated on a contrast-enhanced magnetic resonance imaging (MRI). In humans, it may arise from various benign or malignant clinical processes, such as transient postoperative changes, intracranial hypotension or primary neoplasms, including meningiomas and secondary central nervous system lymphoma, and metastatic disease. The present study describes two clinical cases of canine diffuse intracranial pachymeningeal enhancement as the only intracranial imaging abnormality in a dog with toxoplasma suspected meningitis and in a dog with presumed idiopathic eosinophilic meningitis. Both dogs presented clinical signs compatible with intracranial and spinal disease. Both cases had cerebrospinal fluid analysis results compatible with central nervous system inflammatory disease. Clinical improvements were observed with corticosteroid therapy and worsening of the clinical signs appeared to be associated with corticosteroid tapering in both dogs. Despite the therapy instituted, both patients presented a negative evolution of their neurological condition, and the tutors opted for the euthanasia act at the end of a period of 2 and 7 months after the clinical diagnosis was established. Keywords:
RESUMO - INTENSIFICAÇÃO DO SINAL PAQUIMENÍNGICO CRANIANO CANINO: ESTUDO RETROSPECTIVO DE 2 CASOS CLÍNICOS - A intensificação do sinal paquimeníngico pós-contraste, sinónimo de intensificação do sinal dural ou dural-aracnóide pós-contraste, é um sinal imagiológico melhor apreciado na ressonância magnética (RM) com contraste. No Homem, pode surgir associado a vários processos clínicos benignos ou malignos, como é o caso de alterações pós-cirúrgicas transitórias, hipotensão intracraniana ou neoplasias primárias como meningioma e linfoma do sistema nervoso central e ainda de doença metastática. O presente estudo descreve dois casos clínicos de cães com diagnóstico diferencial primário de meningite por toxoplasma e meningite eosinofílica idiopática, que apresentaram intensificação do sinal paquimeníngico difuso na RM pós-contraste. Ambos os canídeos apresentaram sinais clínicos compatíveis com doença intracraniana e da medula espinhal e uma análise do líquido cefalorraquidiano compatível com doença inflamatória do sistema nervoso central. A instituição de corticoterapia permitiu em ambos os casos uma melhoria clínica, a qual foi agravando à medida que se diminuía a dose do medicamento a que o doente era sujeito. Apesar da terapia instituída, ambos os doentes apresentaram uma evolução negativa do seu quadro neurológico, tendo os cuidadores optado pela realização do acto de eutanásia ao final de um período de 2 e 7 meses após o diagnóstico clínico ter sido estabelecido.
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Books on the topic "Clinical Neurology"

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Aminoff, Michael J. Clinical neurology. 4th ed. New York: Lange Medical Books/McGraw-Hill, Medical Pub. Division, 1999.

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M, Wardlaw Joanna, ed. Clinical neurology. New York: Demos Medical Pub., 2008.

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T, Fowler, ed. Clinical neurology. 2nd ed. London: Arnold, 1998.

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T, Fowler, ed. Clinical neurology. London: E. Arnold, 1989.

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T, Fowler, and Scadding John W, eds. Clinical neurology. 3rd ed. London: Arnold, 2003.

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Gorelick, Philip B., Fernando D. Testai, Graeme J. Hankey, and Joanna M. Wardlaw. Hankey's Clinical Neurology. Edited by Philip B. Gorelick, Fernando D. Testai, Graeme J. Hankey, and Joanna M. Wardlaw. Third edition. | Boca Raton ; London : CRC Press, 2020.: CRC Press, 2020. http://dx.doi.org/10.1201/9780429299476.

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Brain, Brain W. Russell. Brain's Clinical neurology. 6th ed. London: Oxford University Press, 1985.

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Salih, Mustafa A. M., ed. Clinical Child Neurology. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-43153-6.

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Gelb, Douglas James. Introduction to clinical neurology. 3rd ed. Philadelphia, Pa: Elsevier/Butterworth Heinemann, 2005.

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Introduction to clinical neurology. Boston: Butterworth-Heinemann, 1995.

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Book chapters on the topic "Clinical Neurology"

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El-Radhi, A. Sahib. "Neurology." In In Clinical Practice, 137–66. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-41750-5_7.

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Colombo, Joseph, Rohit Arora, Nicholas L. DePace, and Aaron I. Vinik. "General Neurology." In Clinical Autonomic Dysfunction, 299–303. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-07371-2_26.

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Tsui, J. K., M. Schulzer, and D. B. Calne. "Parkinson’s Disease: Clinical Trials." In Neurology, 340–48. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70007-1_50.

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Keller, Matthias, and Elke Griesmaier. "Neonatal Neurology." In Textbook of Clinical Pediatrics, 379–90. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-02202-9_32.

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Tranel, Daniel, and Thomas J. Grabowski. "Behavioral Neurology." In Atlas of Clinical Neurology, 259–87. London: Current Medicine Group, 2009. http://dx.doi.org/10.1007/978-1-57340-359-7_7.

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Tranel, Daniel, Thomas J. Grabowski, and Hanna Damasio. "Behavioral Neurology." In Atlas of Clinical Neurology, 243–67. London: Current Medicine Group, 2003. http://dx.doi.org/10.1007/978-1-4757-4552-8_7.

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Shim, Hyung Sub, and Daniel Tranel. "Behavioral Neurology." In Atlas of Clinical Neurology, 347–90. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-03283-8_7.

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Malik, Mohammed Faysal, Asiya Maula, Dominic Greenyer, and Maurice A. Smith. "Neurology." In The Ultimate Guide to Passing Clinical Medicine Finals, 161–93. London: CRC Press, 2021. http://dx.doi.org/10.1201/9781846198526-7.

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Blessed, G. "Clinical Presentation of the Dementias." In Neurology, 34–42. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70007-1_4.

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Porter, R. J. "Clinical Trials Relating to Epilepsy." In Neurology, 305–12. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70007-1_43.

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Conference papers on the topic "Clinical Neurology"

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Bondarchuk, Vladimir. "NEUROLOGY, REFLEXOLOGY AND MANUAL THERAPY IN CLINICAL PRACTICE." In XVI International interdisciplinary congress "Neuroscience for Medicine and Psychology". LLC MAKS Press, 2020. http://dx.doi.org/10.29003/m960.sudak.ns2020-16/108-109.

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Souza, Gregory Lauar e., Flávio Henrique Batista de Souza, Marconi Augusto Aguiar dos Reis, Raoni Aldrich Dorim, Elisângela Cristine Oliveira Gonçalves, Ana Luiza Silva Floriano, Bruna de Souza Tavares, et al. "Gamification as a Neurology Teaching Method." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.295.

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Background: Digital games play an important role in the learning process, and are used to teach languages and train surgeons. Based on theoretical frameworks that prove the relevance of games in teaching, we began developing a computer game that simulates a hospital, so that medical students could analyze clinical cases from different areas of medical science, including neurology, while playing a game. Objectives: Create a game to teach medicine in a ludic manner. Design and Setting: The game is being developed by Doctors, Programmers, Engineers, students of Medicine, Information Technology (IT), Design and Architecture from Brazil and Peru, in a startup incubator from Centro Universitário de Belo Horizonte, in partnership with the Universidad Científica del Sur, Lima, Peru. Methods: Medical students, under the supervision of Doctors, defined behavioral algorithms, based on Brazilian guidelines, and outcomes (i.e. gain or loss of points, clinical improvement or worsening) addressing different topics in Medicine. Design students created the artistic elements. IT students programmed the prototype of the game using Unity software. Results: An expandable minimum viable product was obtained, with artistic elements of two characters, one being a non-playable character, a scenario, and a dialogue script based on a clinical examination of a patient. Conclusion: The software is running, with the launch of the pre-alpha version in December 2021. A scoring system will be included for qualitative assessment of the player, as well as feedback reports to educate the player. We speculate this game will improve accuracy and clinical skills of medical students.
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Moura, Ludmila Sandy Alves, André Taumaturgo Cavalcanti Arruda, and Mário Luciano de Melo Silva Júnior. "Parallels between neurologist training in Brazil and in other countries." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.534.

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Introduction: Neurology training involves practice in infirmaries and outpatient clinics in several subspecialties, as well as training in procedures and examinations. The analysis of Medical Residency Programs (MRPs) in Neurology in other countries is important to identify points of contrast and similarities as a way to keep the national training equivalent to other countries. Objectives: To analyze the duration and characteristics of the training of neurology physicians in Brazil and other countries. Methods: Cross-sectional study by active search on official web pages of governments and organizations/entities representing neurologists from 12 countries: Australia, Portugal, Italy, Greece, India, USA, Canada, Puerto Rico, Argentina, Chile, Uruguay, and Colombia. Information was obtained on the duration of medical school and residency, as well as the characteristics of this. Results: The duration of medical school was 4 to 7 years (median: 6; IIQ: 0.5). Duration in neurology was 3 to 6 years (median: 4; IIQ:1). Developed countries have a median duration of residency of 4.83 years ± 0.68 years, whereas in developing countries it was 3.66 ±0.47 years. Regarding access, 25% of the countries require a prerequisite. Regarding rotations, those present in most of the programs studied were: neurology outpatient clinic (100%), neuroradiology (83%), neuropediatrics (75%) clinical medicine (58%), psychiatry (58%). Conclusion: We identified differences in the standardization of PRM in Neurology among the countries studied. The duration of Brazilian residency is below the average of the other countries studied, but it includes the required rotations in developed countries.
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Mandrekar, Jay. "Data driven decision making for survey reduction: case study from neurology research." In Decision Making Based on Data. International Association for Statistical Education, 2019. http://dx.doi.org/10.52041/srap.19104.

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The goal of this research was to develop an abbreviated and statistically robust instrument to assess autonomic symptoms that provides clinically relevant scores of autonomic symptom severity based on the well-established questionnaires. Data from 405 healthy control subjects seen at the Mayo Clinic Autonomic Disorders Center were collected. The length of the questionnaire was reduced from a total of 169 to 31 questions using exploratory factor analysis. Our new simplified scoring algorithm resulted in higher Cronbach alpha values in all domains. This reduced instrument allowed researchers to focus on clinically meaningful variables. Also, a shorter survey instrument was less time consuming and less burdensome for critically ill patients, allowing for capturing accurate responses and limiting missing data. The application of exploratory factor analysis in reduction of dimension reduction in this area of neurology research is novel. This reduced survey instrument is now being used to capture data from various clinical studies around the world.
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Ribas, Michelle Zonkowski, Gabriella Augustin, Valéria Cristina Scavasine, Renata Dal Prá Ducci, and Marcos Christiano Lange. "Teleregulation in Neurology: A decision-making process for neurology evaluation in a large Brazilian city." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.106.

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Background: There is an increasing demand for neurological consultations. However, geographical and economic barriers and the long waiting lines limit the access. Teleregulation (TR), an asynchronous evaluation made by the neurologist, could optimize the need for presential evaluation. Objectives: The aim of this study was to analyze TR for neurological referral of patients, regarding the information provided, the main reasons for consultation, and the teleneurologist’s final decision. Design and setting: Observational cross-sectional study in Complexo Hospital de Clínicas in Curitiba-PR. Methods: The study selected neurological referrals for evaluation by TR between October 2018 and February 2020. The referrals who had incomplete information were excluded. The main variables analyzed were age, sex, reasons for TR, and final decision by the teleneurologist. Results: Of the 1035 included referrals, 56% were women and the mean age was 50±19.6 years old. The main reasons for TR were therapeutic conduct (32%), diagnosis (31%), and test request (13%) and the main specific clinical reasons were headache (30%), epilepsy (19%), dementia (16%), cerebrovascular diseases (11%), and neuromuscular disorders (10%). More information was requested in 427 (41%) of the consults and no need for in-person consultation occurred in 713 (68%) of cases. Conclusions: The main reasons for TR were management and diagnosis. The study showed that TR can reduce the need for presential assessment by a neurologist in more than two-thirds of cases. However, a great part of the consultations needed additional data. Thus, the optimization of the referrals could further improve this system, reducing its overhead.
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Flanagan, P. M., J. G. Chutkow, M. T. Riggs, and V. D. Cristiano. "An Intelligent Computerized Stretch Reflex Measurement System For Clinical And Investigative Neurology." In Applications of Artificial Intelligence V, edited by John F. Gilmore. SPIE, 1987. http://dx.doi.org/10.1117/12.940653.

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Shevchenko, O., and S. Vlaho. "Triple X Syndrome and GRIN2A Mutation in the Clinic for Pediatric Neurology: Clinical and EEG Features." In Abstracts of the 46th Annual Meeting of the Society for Neuropediatrics. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1739571.

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Hutchison, Megan, Emily Ogden, Neil Patel, Jay Shetty, and Sameer Zuberi. "1181 Clinical, health economic and environmental evaluation of a secure, carer recorded, clinical video transfer system for paediatric neurology." In Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference, Liverpool, 28–30 June 2022. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2022. http://dx.doi.org/10.1136/archdischild-2022-rcpch.371.

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Horne, A., P. Prabhakar, J. Brierley, and S. Aylett. "G473 A review of the neurology consults of the clinical ethics service at a tertiary children’s hospital." In Royal College of Paediatrics and Child Health, Abstracts of the Annual Conference, 13–15 March 2018, SEC, Glasgow, Children First – Ethics, Morality and Advocacy in Childhood, The Journal of the Royal College of Paediatrics and Child Health. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2018. http://dx.doi.org/10.1136/archdischild-2018-rcpch.461.

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Lemos, Jamilly Rodrigues, and Myrella de Jesus Cruz Gomes. "Neurocall: an explanatory communication platform for diagnostics." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.587.

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Introduction: In the current context of the 21st century, it has become necessary to incorporate new tools to clinical practice, especially those that allow communication at the nationally or internationally remotely, enabling the interruption of diagnostic doubts, joint interpretation of imaging exams, meeting of various protocols and updates in the management of diseases. When there is an application, which brings together specialists in neurology, psychiatry and the like, an ethical, safe and promising environment will be established. Objectives: Reduce diagnostic errors and promote the creation of a virtual Community active disseminator of knowledge in neurology. Design and setting: Quantitative observational study based on the results of a online form applied with professionals from the Uniceuma institution, in force in São Luís, located in the state of Maranhão (Brazil), in the year 2021. Methods: This is a quantitative survey applied to a non-sample probabilistic. The instrument for data collection was Microsoft Forms, with results applied to a Microsoft Excell spreadsheet. Results: Of the 22 selected medical professionals, 14 were neurologists, 3 were psychiatrists and 5 were general practitioners. Among all, 86% of them demonstrated a high degree of of interest in the application, with the 14 neurologists included; all stated that the platform would reduce diagnostic errors and 17 of them would use it in clinical practice. Conclusions: Therefore, there is an urgent need to promote an online teaching tool, responsible and accessible, via IOS and Android, which makes therapeutic conduct feasible, diagnostic thinking and update the medical Community.
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Reports on the topic "Clinical Neurology"

1

Gardner, John M. Neurology Falls. Patient Falls Risk Assessment, Neurology Clinic, Johns Hopkins Hospital, Baltimore, MD. Fort Belvoir, VA: Defense Technical Information Center, July 2009. http://dx.doi.org/10.21236/ada516519.

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Xin, Wu, and Xue Tao. The efficacy and safety of neuromodulation in refractory epilepsy: a systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0042.

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Review question / Objective: To assess the efficacy and safety of different neuromodulation applied to the refractory epilepsy and provide a better choice for clinical practice. Condition being studied: Epilepsy is a frequent neurologic illness defined by bursts of hypersynchronized neural network activity that afflict about 1% of the global population. Unfortunately, roughly 30% of people with drug-resistant epilepsy (DRE) continue to experience seizures despite three anti-seizure drugs. In most cases, resective surgery, as the first-line treatment for DRE, is considered a curative therapy for achieving long-term seizure-free status, but about half of patients are not candidates for surgery due to a variety of factors such as multiple/diffuse/widespread seizure foci, epileptic foci arising from eloquent, primary generalized epilepsy, or patients unwilling to undergo surgery. Neuromodulation, albeit palliative, is an important alternative treatment for these individuals to prevent or decrease ictal episodes, which can affect the nervous system in a variety of ways.
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