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1

CHEW, D. M. "Structural and stratigraphic relationships across the continuation of the Highland Boundary Fault in western Ireland." Geological Magazine 140, no. 1 (January 2003): 73–85. http://dx.doi.org/10.1017/s0016756802007008.

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The relationship between the Dalradian Supergroup and the Highland Border Complex in Scotland has remained contentious for over a century. In western Ireland, the contact between the Dalradian Supergroup and the Clew Bay Complex (a correlative of the Highland Border Complex) is superbly exposed on the island of Achill Beg on the North Mayo coast. The unfossiliferous South Achill Beg succession has been traditionally assigned to the Clew Bay Complex, and this interpretation is supported by a combination of Sm–Nd model age data, heavy mineral analysis and lithostratigraphic correlation. TDM ages range from 1.99–2.66 Ga (mean=2.28 Ga, n=6). Detailed structural mapping shows that both the Dalradian and the Clew Bay Complex share the same structural history. A D1 high strain event is common to both units, and is associated with the development of tectonic slides. The D2 event is responsible for the formation of crustal-scale nappes. In both units, beds are consistently downward facing on the S2 foliation. Later dextral shearing (D3) resulted in the tilting of the originally recumbent, S-facing D2 nappes into this downward-facing orientation. Rb–Sr and 40Ar–39Ar radiometric dating of muscovite confirms that both units were deformed contemporaneously as the S2 nappe fabric in each is dated at c. 460 Ma. This Middle Ordovician age for deformation of the Clew Bay Complex is highly significant, not least because published microfossil data suggest a Silurian age.
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2

RICE, A. H. N., and D. M. WILLIAMS. "Caledonian strike-slip terrane accretion in W. Ireland: insights from very low-grade metamorphism (illite–chlorite crystallinity and b0parameter)." Geological Magazine 147, no. 2 (October 5, 2009): 281–98. http://dx.doi.org/10.1017/s0016756809990446.

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AbstractAnalysis of pelites with detrital white-micas in the Clew Bay–Galway Bay segment of the Irish Caledonides indicates that b0data from whole-rock and < 2 μm fractions generally show differences smaller than the errors of the method, irrespective of (001) illite crystallinity values, probably due to metamorphic recrystallization. Intermediate pressure metamorphism of the Ordovician–Silurian Clew Bay Group indicates slow subduction, allowing partial thermal re-equilibration before exhumation. In contrast, the Croagh Patrick Group Laurentian shelf-sediments underwent high-pressure alteration, suggesting rapid subduction/exhumation, synchronous with strike-slip faulting. The Murrisk Group, which underwent high-intermediate pressure metamorphism in an Ordovician back-arc, forms a separate terrane to the Croagh Patrick Group to the north and also to the Ordovician Lough Nafooey and Tourmakeady groups and Rosroe Formation in the south, in which low-intermediate pressure alteration occurred. These, together with the Silurian North Galway Group, may have undergone heating due to movement over or deposition on the hot Gowlaun Detachment as the Connemara Dalradian was exhumed. The South Connemara Group also underwent a high-pressure alteration, consistent with its inferred subduction environment. Evidence of contact alteration, due to known or inferred buried late- to post-Caledonian granitoid plutons, has been found in the Clew Bay, Louisburg–Clare Island, Croagh Patrick, Murrisk and South Connemara groups. These show evidence of lower-pressure alteration than the surrounding country-rocks.
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3

Johnston, J. D., and W. E. A. Phillips. "Terrane amalgamation in the Clew Bay region, west of Ireland." Geological Magazine 132, no. 5 (September 1995): 485–501. http://dx.doi.org/10.1017/s0016756800021154.

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AbstractThe Caledonides of the west of Ireland provide a well-exposed and well-mapped example of an oblique collision zone. The east-northeast trending Deer Park and Achill Beg Fault system is a crustal scale ductile sinistral strike-slip duplex of late Ordovician age, imbricating late Precambrian granulite facies lower crustal rocks, near eclogite facies supracrustal rocks, up to amphibolite facies Dalradian metasedimentary rocks and greenschist facies Cambro-Ordovician rocks. This fault system is correlated with a pre-Devonian component of the Highland Boundary Fault system in southern Scotland. In the Clew Bay area, the high pressure-low temperature facies metamorphic rocks, in tectonic contact with greenschist facies Cambro-Ordovician rocks, are together interpreted as an accretionary prism complex related to northwestward directed subduction. Both of these are allocthonous terrains with respect to the Dalradian terrane to the north (North West Mayo). To the south, the Cambro-Ordovician rocks docked with a probable Dalradian block containing ultramafic intrusives (Deer Park Complex) during the late Ordovician. The Deer Park Complex and South Mayo Trough linked earlier, during the Arenig.Silurian and Lower-Middle Devonian redbed successions sit unconformably on the metamorphic rocks. Deposition and deformation of these cover rocks was controlled by oblique strike-slip movements on the Leek Fault whose strike swings from west-northwest to north-northeast, following earlier basement trends, as it is traced eastwards from Clew Bay. The Leek Fault System may be correlated with the Leannan Fault of northwest Donegal, a splay of the Great Glen Fault system of central Scotland. East of Clew Bay, this sinistral shear generated local dilation on the more northerly trending bend of the Leek Fault. Lower and Middle Old Red Sandstone redbeds were developed here. The west-northwest trend of the Leek Fault in Clew Bay acted as a compressional bend during these sinistral movements and transpressional southwest directed thrusting developed in Silurian rocks. Post-Middle Old Red Sandstone pre-late Tournaisian dextral displacement on the Leek Fault reversed this pattern with transtension in Clew Bay allowing intrusion of small carbonated peridotite bodies into Silurian rocks and easterly directed thrusting of Middle Old Red Sandstone rocks east of the Bay on the transpressional north-south bend.A tectonic model for the region is presented here. This model involves a northwestward directed subduction system, 150 to 750 km of Arenig sinistral strike slip movement, and eastwards insertion of the Connemara block with formation of the Ordovician South Mayo Trough as a pull-apart basin. Subsequently, a further 130 to 650 km eastward displacement of rocks took place south of the Deer Park Fault in later Ordovician times. The magnitudes of these estimates are directly proportional to an assumed maximum wavelength of 1500 km for promontories on the original Laurentian margin, and using the current juxtaposition of terranes, a minimum wavelength of 300 km is inferred.
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4

Knight, Jasper. "Subglacial processes from drumlins in Clew Bay, western Ireland." Earth Surface Processes and Landforms 41, no. 2 (December 16, 2015): 277–88. http://dx.doi.org/10.1002/esp.3865.

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5

Williams, D. M. "Evolution of Ordovician terranes in western Ireland and their possible Scottish equivalents." Transactions of the Royal Society of Edinburgh: Earth Sciences 81, no. 1 (1990): 23–29. http://dx.doi.org/10.1017/s0263593300005101.

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ABSTRACTIn the W of Ireland the Ordovician rocks of South Mayo and Clew Bay are now juxtaposed but a comparison of the sedimentary histories of these two sequences shows that they accumulated in basins which were probably separated during most of their history. The large amount of terrigenous detritus present in the Arenig to Llanvirn elements of the South Mayo succession is not manifest in that of Clew Bay until the Llandeilo/Caradoc, by which time sedimentation in South Mayo had ceased. A comparison of the South Mayo Ordovician with that of Girvan in Scotland demonstrates that both sequences had a similar provenance. This source contained an ophiolite, granites and some (probably pre-Dalradian) metamorphic rocks. Sediment dispersal directions for the two sequences are opposite in sense, being primarily northward in South Mayo and southward at Girvan. The two stratigraphies indicate that basement subsidence behaviour in South Mayo was virtually the opposite of that at Girvan where initial shallow water sedimentation was rapidly succeeded by deep water environments at the end of the Llanvirn. The two basins may thus have been marginal to a single Ordovician arc complex. One reason for the opposite sense of basin subsidence may lie in the suggested reversal of subduction polarity during the Ordovician. In this scenario the South Mayo basin may be envisaged as lying to the N of a northward-facing arc during the early Ordovician. A new, northward, subduction direction instigated during the Llanvirn, resulted in a fore-arc basin at Girvan complemented by a closing back-arc basin in South Mayo.
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6

TANNER, P. W. G. "The role of the Highland Border Ophiolite in the ∼ 470 Ma Grampian Event, Scotland." Geological Magazine 144, no. 3 (April 20, 2007): 597–602. http://dx.doi.org/10.1017/s0016756807003342.

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Field and petrological studies of the Highland Border Ophiolite demonstrate that it was obducted onto the Neoproterozoic–Ordovician rocks of the Dalradian block, and not emplaced against them by post-orogenic strike-slip movement. It was welded onto the upper, southward-younging limb of the already recumbent Tay Nappe (D1), and deformed by the Downbend Antiform (D4). However, its emplacement was not accompanied by significant internal deformation of the Dalradian block. As the ophiolite is correlated with those at Clew Bay, Tyrone and Shetland, this result will necessitate complete revision of the current model for basin closure on the southeastern margin of Laurentia.
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7

PALMER, D., J. D. JOHNSTON, T. DOOLEY, and K. MAGUIRE. "Short paper: The Silurian of Clew Bay, Ireland: part of the Midland Valley of Scotland?" Journal of the Geological Society 146, no. 3 (May 1989): 385–88. http://dx.doi.org/10.1144/gsjgs.146.3.0385.

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8

McCAFFREY, K. J. W. "Controls on reactivation of a major fault zone: the Fair Head–Clew Bay line in Ireland." Journal of the Geological Society 154, no. 1 (January 1997): 129–33. http://dx.doi.org/10.1144/gsjgs.154.1.0129.

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9

Harkin, J., D. M. Williams, J. F. Menuge, and J. S. Daly. "Turbidites from the Clew Bay Complex, Ireland: provenance based on petrography, geochemistry and crustal residence values." Geological Journal 31, no. 4 (December 1996): 379–88. http://dx.doi.org/10.1002/(sici)1099-1034(199612)31:4<379::aid-gj719>3.0.co;2-x.

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10

Max, Michael D. "The clew bay group: A displaced terrane of highland border group rocks (Cambro-ordovician) in Northwest Ireland." Geological Journal 24, no. 1 (April 30, 2007): 1–17. http://dx.doi.org/10.1002/gj.3350240102.

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11

WILLIAMS, D. M., J. HARKIN, and K. T. HIGGS. "Implications of new microfloral evidence from the Clew Bay Complex for Silurian relationships in the western Irish Caledonides." Journal of the Geological Society 153, no. 5 (September 1996): 771–77. http://dx.doi.org/10.1144/gsjgs.153.5.0771.

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12

Ryan, P. D., N. J. Soper, D. B. Snyder, R. W. England, and D. H. W. Hutton. "The Antrim–Galway Line: a resolution of the Highland Border Fault enigma of the Caledonides of Britain and Ireland." Geological Magazine 132, no. 2 (March 1995): 171–84. http://dx.doi.org/10.1017/s0016756800011730.

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AbstractThe westward continuation of the Highland Border fault of Scotland (HBFZ) into Ireland is problematic. It is widely thought to follow a pronounced magnetic and gravity lineament, the Fair Head-Clew Bay Line (FCL). The advantage of this interpretation is that it places all the Ordovician ophiolitic complexes and associated sedimentary basins to the south of the FCL, which would represent the contact between Laurentia and the outboard terranes. Its main shortcomings are that both the deep structure and timing of strike-slip are different on the HBFZ and FCL. In Ireland the FCL is a north-dipping feature that can be traced to the Moho on BIRPS profiles, while the HBFZ has no such signature. Terrane amalgamation in western Ireland was completed by the late Ordovician, while in Scotland the Midland Valley terrane did not finally dock until the early Devonian. These considerations suggest that in western Ireland a branch of the HBFZ exists, which was active in post-Ordovician time and must lie south of Connemara. An examination of Irish geological, geophysical and image-processed magnetic data shows that a profound lineament can be traced from Antrim to Galway Bay (the Antrim–Galway Line). Stitching plutons date movement on it as pre-405 Ma. We propose that the Antrim–Galway Line represents the continuation of the Scottish HBFZ, while the FCL is a preserved Ordovician splay of the HBFZ system whose northdipping geometry is a product of Ordovician collapse of the orogen in western Ireland.
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13

Dewey, John F., and Paul D. Ryan. "Connemara: its position and role in the Grampian Orogeny." Canadian Journal of Earth Sciences 53, no. 11 (November 2016): 1246–57. http://dx.doi.org/10.1139/cjes-2015-0125.

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In the Irish and British Caledonides, the early Ordovician Grampian Orogeny was the result of collision between the Laurentian rifted margin and an oceanic island arc. The Connemara terrain in western Ireland differs in position and character from all other parts of the exposed Dalradian rocks of the Grampian Orogen in lying south of the collided arc and fore-arc, and in having north-verging fold nappes that developed synchronously with the intrusion of huge volumes of calc-alkaline magmas that provided the heat for regional Barrovian metamorphism. We have tested this hypothesis with a numerical model, which demonstrates its admissablity. Connemara is not a terrane, displaced with respect to the remainder of the Grampian Orogen but was overridden, northwards, by the arc and its fore-arc basin (South Mayo Trough), frontal ophiolite complex (Deer Park) and accretionary complex (Killadangan). Deposition in the South Mayo Trough occurred below sea level and above the evolving Grampian Orogen, which developed on a hyper-extended rifted margin bounded to the north by the Clew Bay Line.
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14

Max, M. D., D. Rex, and J. A. Winchester. "The farnacht formation along the south side of the clew bay fault zone, Western Ireland: Its chemistry and age of metamorphism." Geological Journal 23, no. 3 (April 30, 2007): 249–60. http://dx.doi.org/10.1002/gj.3350230305.

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15

Hiemstra, John F., Bernd Kulessa, Edward C. King, and Dimitris Ntarlagiannis. "The use of integrated sedimentological and geophysical methods in drumlin research - a case study of Pigeon Point, Clew Bay, Northwest Ireland." Earth Surface Processes and Landforms 36, no. 14 (August 19, 2011): 1860–71. http://dx.doi.org/10.1002/esp.2207.

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16

McCaffrey, Kenneth J. W. "Magmatic and solid state deformation partitioning in the Ox Mountains granodiorite." Geological Magazine 131, no. 5 (September 1994): 639–52. http://dx.doi.org/10.1017/s0016756800012437.

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AbstractThe Ox Mountains granodiorite (western Ireland) is situated along the Fair Head—Clew Bay line, a major Caledonian structure. The pluton was emplaced synchronously with respect to deformation on a major strike-slip shear zone system and experienced a pervasive episode of sinistral shear. Remnants of magmatic state deformation such as phenocryst alignments and tiling fabrics are present. An early phase of strain partitioning produced sinistral offsets on internal contacts. These structures were overprinted by a solid state fabric characterized by crystal plastic deformation in feldspar and the operation of recovery processes during quartz deformation indicating temperatures in the range 450–500 °C. A sinistral shear band fabric is ubiquitous and its formation was enhanced by myrmekite production leading to the formation of fine-grained feldspar and quartz. Late deformation partitioning during further pluton cooling produced a conjugate shear zone system containing mylonites. Deformation within the Ox Mountains granodiorite provides important constraints on the nature of late Caledonian age mid-crustal deformation along the Highland Boundary fault. The pluton also provides exceptional examples of the range of structures that may form in a syntectonic pluton.
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17

McManus, Catherine, Alistair McIlgorm, Rachel Nichols, and Andrew Cooper. "An initial consideration of data availability issues in downscaling ocean accounting to inform sustainable aquaculture development: The example of Clew Bay, Ireland." Marine Policy 145 (November 2022): 105286. http://dx.doi.org/10.1016/j.marpol.2022.105286.

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18

Gilligan, M., A. Costanzo, M. Feely, G. K. Rollinson, E. Timmins, T. Henry, and L. Morrison. "Mapping arsenopyrite alteration in a quartz vein-hosted gold deposit using microbeam analytical techniques." Mineralogical Magazine 80, no. 5 (August 2016): 739–48. http://dx.doi.org/10.1180/minmag.2016.080.019.

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AbstractAn unworked quartz vein-hosted gold deposit occurs in the Clew bay area of County Mayo, western Ireland. The veins are late-Caledonian in age and transect greenschist-facies poly-deformed Silurian quartzites. The veins contain disseminated arsenopyrite that may be a primary mineral source for elevated levels of arsenic (As) found in groundwater samples recovered from wells related spatially to the gold deposit. Levels from 5 to 188 μg/L (significantly above the 7.5 μg/L threshold for safe drinking water) have been detected. A series of element distribution maps using a scanning electron microscope (Hitachi model S-4700) linked to an energy-dispersive spectrometer (INCA® Oxford Instruments) and mineral distribution maps generated by QEMSCAN® (Quantitative Evaluation of Minerals by Scanning electron microscopy) were used to map the distribution of the primary arsenopyrite and related secondary As-bearing phases. Laser Raman microspectroscopy was used to identify the secondary As-bearing phases. 'Island weathering' of primary arsenopyrite together with hydrated pseudomorphs of arseniosiderite, pharmacosiderite and scorodite after arsenopyrite are recorded. Circulating groundwater hydrates the primary arsenopyrite, providing the release mechanism that forms the secondary As-bearing phases that occur as microfracture infills together with muscovite and biotite. The textural relationships between the primary and secondary As minerals indicate their potential as mineral sources of As that could enter transport pathways leading to its release into groundwater.
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19

Barker, Judith. "CLEO/IQEC assembles in the city by the bay." Physics Today 57, no. 4 (April 2004): 84–85. http://dx.doi.org/10.1063/1.1752427.

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20

Lax, Siân, Julie Rayes, Surasak Wichaiyo, Elizabeth J. Haining, Kate Lowe, Beata Grygielska, Ryan Laloo, et al. "Platelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse." American Journal of Physiology-Lung Cellular and Molecular Physiology 313, no. 6 (December 1, 2017): L1016—L1029. http://dx.doi.org/10.1152/ajplung.00023.2017.

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There is no therapeutic intervention proven to prevent acute respiratory distress syndrome (ARDS). Novel mechanistic insights into the pathophysiology of ARDS are therefore required. Platelets are implicated in regulating many of the pathogenic processes that occur during ARDS; however, the mechanisms remain elusive. The platelet receptor CLEC-2 has been shown to regulate vascular integrity at sites of acute inflammation. Therefore the purpose of this study was to establish the role of CLEC-2 and its ligand podoplanin in a mouse model of ARDS. Platelet-specific CLEC-2-deficient, as well as alveolar epithelial type I cell (AECI)-specific or hematopoietic-specific podoplanin deficient, mice were established using cre-loxP strategies. Combining these with intratracheal (IT) instillations of lipopolysaccharide (LPS), we demonstrate that arterial oxygen saturation decline in response to IT-LPS in platelet-specific CLEC-2-deficient mice is significantly augmented. An increase in bronchoalveolar lavage (BAL) neutrophils and protein was also observed 48 h post-IT-LPS, with significant increases in pro-inflammatory chemokines detected in BAL of platelet-specific CLEC-2-deficient animals. Deletion of podoplanin from hematopoietic cells but not AECIs also reduces lung function and increases pro-inflammatory chemokine expression following IT-LPS. Furthermore, we demonstrate that following IT-LPS, platelets are present in BAL in aggregates with neutrophils, which allows for CLEC-2 interaction with podoplanin expressed on BAL inflammatory alveolar macrophages. Taken together, these data suggest that the platelet CLEC-2-podoplanin signaling axis regulates the severity of lung inflammation in mice and is a possible novel target for therapeutic intervention in patients at risk of developing ARDS.
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21

De Smet, Willem H., and Alexei V. Chernyshev. "Two new species of Dicranophoridae (Rotifera: Monogononta) from Peter the Great Bay, Sea of Japan." Journal of the Marine Biological Association of the United Kingdom 86, no. 4 (June 15, 2006): 657–63. http://dx.doi.org/10.1017/s0025315406013543.

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Two new species of rotifer belonging to the Dicranophoridae, and provisionally placed in the genus Encentrum, are described from littoral psammon from the Ussuriyskiy Bay, Peter the Great Bay, Sea of Japan, Russia. Encentrumkutikovae sp. nov. is characterized by a long foot consisting of three pseudosegments, cylindrical toes, a hexagonal rami outline, and the right ramus showing an accessory chamber with alula. Encentrum ussuriensis sp. nov. is characterized by unusual stout toes with claw, an oblong-ovate and latero-caudal weakly angular rami outline, the right ramus bearing an alula, and the left one showing an accessory chamber.
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22

Saffra, Norman, Aleksandr Rakhamimov, Robert Masini, and Kenneth J. Rosenthal. "Anterior Chamber Iris Claw Lens for the Treatment of Aphakia in a Patient with Megalocornea." Case Reports in Ophthalmology 6, no. 2 (June 2, 2015): 164–69. http://dx.doi.org/10.1159/000431251.

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Megalocornea in isolation is a rare congenital enlargement of the cornea greater than 13 mm in diameter. Patients with megalocornea are prone to cataract formation, crystalline lens subluxation, zonular deficiencies and dislocation of the posterior chamber intraocular lens (PCIOL) within the capsular bag. A 55-year-old male with megalocornea in isolation developed subluxation of the capsular bag and PCIOL. The PCIOL and capsular bag were explanted, and the patient was subsequently implanted with an anterior chamber iris claw lens. An anterior chamber iris claw lens is an effective option for the correction of aphakia in patients with megalocornea.
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23

MOMTAZI, FARZANEH, ABDOLVAHAB MAGHSOUDLOU, and JEAN JUST. "A new species of Cephaloecetes (Bubocorophiina) from the Iranian coasts of the Gulf of Oman and the Hormuz Strait (Crustacea: Amphipoda: Siphonoecetini)." Zootaxa 4504, no. 1 (October 23, 2018): 128. http://dx.doi.org/10.11646/zootaxa.4504.1.7.

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The first member of Cephaloecetes in the north-western part of the Indian Ocean, Cephaloecetes ungulatus sp. nov., is described from Chabahar Bay, the Gulf of Oman and Qeshm Island in the western Hormuz Strait, Iran. The new species is characterized from the other two species of genus Cephaloecetes by a unique claw-shaped ventral plate on antenna 2 article 2.
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24

Luo, Zhong Hua, and She Huan Li. "Optimization Design for Crank Arc Guide Bar Gathering Mechanism of Crab Claw Type Loading Machine." Applied Mechanics and Materials 229-231 (November 2012): 547–50. http://dx.doi.org/10.4028/www.scientific.net/amm.229-231.547.

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This paper conducts a comprehensive study on the optimization design for crank arc guide bar gathering mechanism of crab claw type loading machine. The optimization aim is to make reality locus of gathering claw end-point be as in-accordance as possible with ideal locus, and so on. Formulae are derived for displacement of gathering claw end-point and position angle of the gathering claw. An optimization design model is established for the crank arc guide bar gathering mechanism. The crank arc guide bar gathering mechanism is optimized of crab claw type loading machine with 2100 mm wide, and the optimization result is satisfactory. Compared to the optimized crank straight line guide bar gathering mechanism in literature [2], the locus error function of gathering claw end-point has been largely improved with a reduction of 25.8%.
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25

McCLELLAND, JAMES. "Losing Grip: Emerson, Leroux and the Work of Identity." Journal of American Studies 39, no. 2 (August 2005): 239–55. http://dx.doi.org/10.1017/s0021875805009709.

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If Minerva offered me an option, I would say give me continuity. I am tired of scraps. I do not wish to be a literary or intellectual chiffonier. Away with this Jew's rag-bag of ends and tufts of brocade, velvet and cloth-of-gold; let me spin some yards or miles of helpful twine, a clew to lead to one kingly truth, a cord to bind wholesome and belonging facts.
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Wang, Xu-Chen, Huan Feng, and Hai-Qing Ma. "Assessment of Metal Contamination in Surface Sediments of Jiaozhou Bay, Qingdao, China." CLEAN – Soil, Air, Water 35, no. 1 (February 2007): 62–70. http://dx.doi.org/10.1002/clen.200600022.

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Lei, Dan, Jia Liu, Junwei Zhang, Andreas Lorke, Shangbin Xiao, Yuchun Wang, Wei Wang, and Ye Li. "Methane Oxidation in the Water Column of Xiangxi Bay, Three Gorges Reservoir." CLEAN – Soil, Air, Water 47, no. 9 (September 2019): 1800516. http://dx.doi.org/10.1002/clen.201800516.

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M. D., Balaji, Sowmya S., and Naveen K. S. "Congenital lobar emphysema presenting as recurrent pneumonia in an infant." International Journal of Contemporary Pediatrics 4, no. 2 (February 22, 2017): 655. http://dx.doi.org/10.18203/2349-3291.ijcp20170726.

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Congenital lobar emphysema (CLE) is a developmental anomaly of the lower respiratory tract, which is characterised by hyperinflation of one or more lobes of lung. CLE is potentially reversible, though possible life threatening cause of respiratory distress in neonate. Here we present a 4 months baby who presented with respiratory distress related to CLE.
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29

Tian, Li, Fan Cheng, Lei Wang, Wen Qin, Kun Zou, and Jianfeng Chen. "CLE-10 from Carpesium abrotanoides L. Suppresses the Growth of Human Breast Cancer Cells (MDA-MB-231) In Vitro by Inducing Apoptosis and Pro-Death Autophagy Via the PI3K/Akt/mTOR Signaling Pathway." Molecules 24, no. 6 (March 20, 2019): 1091. http://dx.doi.org/10.3390/molecules24061091.

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Background: The antitumor activity of CLE-10 (4-epi-isoinuviscolide), a sesquiterpene lactone compound, isolated from Carpesium abrotanoides L. has rarely been reported. The aim of this study is to investigate the antitumor activity of CLE-10 and give a greater explanation of its underlying mechanisms. Methods: The cytotoxicity of CLE-10 was evaluated using MTT assay. Autophagy was detected by the formation of mRFP-GFP-LC3 fluorescence puncta and observed using transmission electron microscopy, while flow cytometry was employed to detect apoptosis. The protein expressions were detected through Western blotting. Results: CLE-10 induced pro-death autophagy and apoptosis in MDA-MB-231 cells by increasing the protein expression of LC3-II, p-ULK1, Bax, and Bad, as well as downregulating p-PI3K, p-Akt, p-mTOR, p62, LC3-I, Bcl-2, and Bcl-xl. CLE-10 that was pretreated with 3-methyladenine (3-MA) or chloroquine (CQ) weakened the upregulation of the protein expression of p-ULK1, or the downregulation of p62, p-mTOR, and decreased the level of cytotoxicity against MDA-MB-231 cells. Meanwhile, rapamycin enhanced the effect of CLE-10 on the expression of autophagy-related protein and its cytotoxicity, with the IC50 value of CLE-10 decreasing from 4.07 µM to 2.38 µM. Conclusion: CLE-10 induced pro-death autophagy and apoptosis in MDA-MB-231 cells by upregulating the protein expressions of LC3-II, p-ULK1, Bax, and Bad and downregulating p-PI3K, p-Akt, p-mTOR, p62, Bcl-2, and Bcl-xl.
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Milke, Lisa M., and Victor S. Kennedy. "Mud crabs (Xanthidae) in Chesapeake Bay: claw characteristics and predation on epifaunal bivalves." Invertebrate Biology 120, no. 1 (May 12, 2005): 67–77. http://dx.doi.org/10.1111/j.1744-7410.2001.tb00027.x.

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Crook, Ashley D., Andrew C. Willoughby, Ora Hazak, Satohiro Okuda, Kylie R. VanDerMolen, Cara L. Soyars, Pietro Cattaneo, et al. "BAM1/2 receptor kinase signaling drives CLE peptide-mediated formative cell divisions inArabidopsisroots." Proceedings of the National Academy of Sciences 117, no. 51 (December 7, 2020): 32750–56. http://dx.doi.org/10.1073/pnas.2018565117.

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Cell division is often regulated by extracellular signaling networks to ensure correct patterning during development. InArabidopsis, the SHORT-ROOT (SHR)/SCARECROW (SCR) transcription factor dimer activatesCYCLIND6;1(CYCD6;1) to drive formative divisions during root ground tissue development. Here, we show plasma-membrane-localized BARELY ANY MERISTEM1/2 (BAM1/2) family receptor kinases are required forSHR-dependent formative divisions andCYCD6;1expression, but notSHR-dependent ground tissue specification. Root-enriched CLE ligands bind the BAM1 extracellular domain and are necessary and sufficient to activateSHR-mediated divisions andCYCD6;1expression. Correspondingly, BAM-CLE signaling contributes to the restriction of formative divisions to the distal root region. Additionally, genetic analysis reveals that BAM-CLE and SHR converge to regulate additional cell divisions outside of the ground tissues. Our work identifies an extracellular signaling pathway regulating formative root divisions and provides a framework to explore this pathway in patterning and evolution.
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Cronin-Hennessy, Daniel. "Measurement of |Vcb| with $\bar{B}^0 \rightarrow D^{*+} \ell^- \bar{\nu}$ at CLEO." International Journal of Modern Physics A 16, supp01b (September 2001): 639–41. http://dx.doi.org/10.1142/s0217751x01007674.

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We determine the CKM matrix element, |Vcb|, by measuring the differential decay rate of B→D*+ℓν as a function of w=vB · vD*. We extrapolate the decay rate to the kinematic point, w=1, where the form factor, ℱ(w), is accurately predicted by theory. We find ℱ(1)|Vcb|=0.0424±0.0018( stat. )±0.0019( syst. ). Integration of the differential decay rate, dΓ/dw, yields the B→D*+ℓν branching fraction, ℬ(B→D*+ℓν)=(5.66±0.29±0.33)%. The data are derived from 3.3 million [Formula: see text] events collected by the CLEO detector at CESR.
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Kumar, Kotra Krishna. "Geomorphological Impact Assessment on Groundwater Quality and Fluoride Genesis along the Bay of Bengal of Visakhapatnam District, Andhra Pradesh, India." CLEAN - Soil, Air, Water 39, no. 10 (August 17, 2011): 925–30. http://dx.doi.org/10.1002/clen.201000520.

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Cao, Lei, Jinming Song, Xuegang Li, Huamao Yuan, Ning Li, Liqin Duan, and Qidong Wang. "Geochemical Characteristics of Soil C, N, P, and Their Stoichiometrical Significance in the Coastal Wetlands of Laizhou Bay, Bohai Sea." CLEAN - Soil, Air, Water 43, no. 2 (May 30, 2014): 260–70. http://dx.doi.org/10.1002/clen.201300752.

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Chen, Guang-Pei. "MEASUREMENT OF THE $D \bar{D}$ CROSS SECTIONS AND D HADRONIC BRANCHING FRACTIONS." International Journal of Modern Physics A 20, no. 16 (June 30, 2005): 3701–3. http://dx.doi.org/10.1142/s0217751x05027369.

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Using 57.2 pb-1 of data collected with the CLEO-c detector at the ψ(3770) resonance, we measure absolute branching fractions for three D0 and two D+ Cabibbo-allowed hadronic decay modes, and the cross section for [Formula: see text] at [Formula: see text].
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36

Santoso, Joko, and Heru Nurcahyo. "FORMULASI EKTSTRAK POLIHERBAL KOMBINASI EKSTRAK TULANG CEKER AYAM TERHADAP BAKTERI STAPILOCOCUS AUREUS." Jurnal Ilmiah Manuntung 5, no. 2 (January 2, 2020): 183. http://dx.doi.org/10.51352/jim.v5i2.279.

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The development of traditional plants as herbal medicines continues to be increased, especially in local use. Aloe vera (Aloe vera), bay leaf (Eugenia polyantha) and Turmeric Rhizome (Curcuma domestica Val) have compounds that function as antibacterial. Chicken claw bones play a role in accelerating the growth of skin cells, but it also has the potential as an antibacterial. This combination is expected to increase the work of medicinal ingredients in killing bacteria. The work method begins with the selection of herbal ingredients, dry sorting, wet sorting and slicing. Drying the sample using an oven at a temperature of 40 which is then pollinated and sieved with 100 mesh. Before macerated with 70% ethanol solvent 1:10 ratio, the sample was tested microscopically. The extract was made of three formulas and tested for antibacterial activity in Stapilococus aureus bacteria using the well method. The antibacterial activity in formula 1 was 7.1mm, Formula 2 was 8.7mm and formula 3 was 10.2mm. Experiments were also carried out on extracts without collagen extracts with better inhibitory results compared to polyherbal extract combinations of collagen extracts. This research proves that polyherbal extract from chicken claw collagen extract has the ability of antibacterial activity. Formula 3 has the best inhibition compared to formulas 1 and 2.
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Sarkar, Santosh Kumar, Henrique Cabral, Mousumi Chatterjee, Ines Cardoso, Asok Kumar Bhattacharya, Kamala Kanta Satpathy, and Mohammad Aftab Alam. "Biomonitoring of Heavy Metals Using the Bivalve Molluscs in Sunderban Mangrove Wetland, Northeast Coast of Bay of Bengal (India): Possible Risks to Human Health." CLEAN – Soil, Air, Water 36, no. 2 (February 2008): 187–94. http://dx.doi.org/10.1002/clen.200700027.

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38

Orr, Robert S. "Experimental Status of $B^0 \bar{B}^0$ mixing." International Journal of Modern Physics A 02, no. 04 (August 1987): 923–41. http://dx.doi.org/10.1142/s0217751x87000363.

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The experimental status of [Formula: see text] mixing is reviewed. The ARGUS experiment has recently reported evidence for substantial mixing in the [Formula: see text] system. UA1 has also reported evidence for mixing, but this cannot be unambiguously interpreted to yield a measurement of the amount of mixing in the [Formula: see text] system. The CLEO, Mk. II, and JADE experiments have all reported upper limits, and the MAC experiment a lower limit, which are compatible with the ARGUS and UA1 results.
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Paktinat-Saeij, Saeid, Mohammad Bagheri, and Michael Skvarla. "First record of the genus Bak Yunker (Acariformes: Prostigmata: Cheyletidae) from Iran with description of a new species." Acarologia 57, no. 4 (July 4, 2017): 847–53. http://dx.doi.org/10.24349/acarologia/20174199.

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A new species, Bak iranica sp. nov. (Acariformes: Prostigmata: Cheyletidae) is described on the basis of adult males from Amol, Mazandaran province, northern Iran. The new species can be distinguished from other species by the following features: having one seta on each trochanter, tarsi I–IV with 9(+1ω)–7(+1ω)–7(+1ω)–7(+1ω); palpal claw with two basal teeth and most of dorsal body setae slightly lanceolate and barbed. Additionally, a key to world species (females and males) of the genus Bak Yunker is provided. This genus is recorded from Iran for the first time.
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Macaulay-Lewis, Elizabeth. "Designing for Luxury on the Bay of Naples: Villas and Landscapes (c.100 bce –79 ce ) by Mantha Zarmakoupi." Classical World 108, no. 3 (2015): 439–40. http://dx.doi.org/10.1353/clw.2015.0042.

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41

DUBYNSKIY, S., and M. B. VOLOSHIN. "POSSIBLE NEW RESONANCE AT THE $D^*\bar D^*$ THRESHOLD IN e+e- ANNIHILATION." Modern Physics Letters A 21, no. 37 (December 7, 2006): 2779–87. http://dx.doi.org/10.1142/s0217732306022195.

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We argue that the recent CLEO-c data on e+e- annihilation into pairs of charmed mesons at c.m. energy around 4.0 GeV are not well described by a single resonance ψ(4040), but can be better understood if there is an additional narrow resonance with mass within few MeV from the [Formula: see text] threshold.
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Kibar, Murat, and Tamer Çağlayan. "Effect of Hoof Trimming on Milk Yield in Dairy Cows with Foot Disease." Acta Scientiae Veterinariae 44, no. 1 (March 19, 2018): 7. http://dx.doi.org/10.22456/1679-9216.81077.

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Backround: Milk is produced at the cost of other metabolic processes in the body and high milk yield has been associated with lameness and claw lesions. Lameness has also been associated with a decrease in milk yield. In the past, claw disorders and lameness in dairy cattle have been an increasing problem of the modern dairy industry. Hoof trimming is performed to prevent hoof lesions and improve gait by correction and maintenance of the hoof symmetry and shape. Lameness caused by hoof disorders can be treated by correct hoof trimming. The aim of this study was to test the hypothesis that one-time claw trimming affect the milk production in dairy cattle with hoof disorders on commercial dairy farms.Materials, Methods & Results: Milk yield level was examined before and after claw trimming in dairy cattle. Eighteen Holstein dairy cows were examined on a commercial dairy farm. Calving number, calving time, lactation number, lactation stage, culling date and milk yield in liters were detected from farm recording system. All cows were visual signs of claw disorders or lameness. Their hooves had not been were trimmed for several years. Trimming technique included leveling the 2 claws, aiming for symmetric bulbs. The axial and abaxial walls were both intended to be parts of the bearing surface and the 2 claws were trimmed flat and balanced with each other. The caudal two-thirds of the axial sole of both claws were sloped toward the interdigital area. All of the cows checked for hoof diseases. The period of observation spanned 45 d, starting day of claw trimming. The observation period was the lactation when the claw trimming was performed. Milk yield was performed one day before and 10, 30, and 45 days after hoof trimming. Cows that were in the mid to late lactation period were selected for the study. The mean days in milk for the group was 221.8 (150-272 days) and the mean number of calvings was 2.8 times (range: 2-5 times) before trimming.Discussion: The shape of the lactation curve is influenced by herd factors such as management and nutrition and individual factors like genetics, parity, and disease. Discrepancies in the literature with regard to the effect of lameness and claw lesions on milk yield are partly the result of these complex influences. Daily milk production of cows in the current study averaged 21 L/d, so milk weight represented approximately 3% of a cow’s body weight per milking. In this study cows were 2 to 5th lactation. Most hoof diseases are accrued around the time of calving. Hoof diseases is becomed visible on the bearing surface of the sole after 2 to 3 months such as white-line disease, sole ulcer, and hemorrhages. We assessed milk yield as the one time claw trimming performed, so any possible healing effect of claw trimming could have led to an underestimation of any negative effects of bad claw health on milk production. Cows with painful claw lesions eat less, are more reluctant to move, and might consequently produce less milk than cows without claw lesions. The significant associations between most claw disorders and increased yield in this study do not prove direct relationships. At claw trimming, the average lactation stage in first parity was 148 DIM; 25% of the cows were before 74 DIM and 25% were later than 226 DIM. After the claw trimming between days 10-30 and 10-45 were determined differences in milk yield (P < 0.05; P < 0.01). In conclusion, this study showed that one time hoof trimming during the lactation period changed the milk yield of the dairy cows with hoof diseases.
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Basu, Sriparna, Aditya Kumar Gupta, and Ashok Kumar. "Congenital lobar emphysema mimicking as persistent pneumonia in a newborn." Clinics and Practice 1, no. 4 (November 7, 2011): 101. http://dx.doi.org/10.4081/cp.2011.e101.

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Congenital lobar emphysema (CLE) is an uncommon congenital malformation of the lung that can present with respiratory distress in early life. We report a full term female baby who presented with intermittent bluish discoloration of the lips and extremities during crying since birth. An initial diagnosis of left sided collapse-consolidation with right-sided compensatory emphysema was made from chest xray. When no improvement was noted after intravenous antibiotic therapy for 7 days, computerized tomographic scan of thorax was done which showed emphysema of the right middle lobe with transherniation and mediastinal shift to the left. Right middle lobectomy was done and postoperative period was uneventful. Histopathological examination of the specimen confirmed the diagnosis of CLE. CLE can mimic more common causes of respiratory distress in neonatal period and needs a high index of suspicion for diagnosis. Early diagnosis and effective surgical treatment is curative.
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44

Mulligan, Bret. "Bad Scorpion: Cacemphaton and Poetics in Martial's Ligurinus-Cycle." Classical World 106, no. 3 (2013): 365–95. http://dx.doi.org/10.1353/clw.2013.0056.

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45

., Ismawati, and Indryani . "Relationship of Risk Factors for Pregnant Women with Congenital Disorders of Lobster Claw Syndrome, Ulutaue Hamlet, Mario Village, Mare District, Bone Regency, South Sulawesi." International Journal of Science and Healthcare Research 7, no. 2 (June 30, 2022): 389–93. http://dx.doi.org/10.52403/ijshr.20220454.

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The health condition of pregnant women is one of the risks that can increase the occurrence of congenital abnormalities; the prevalence of babies with congenital disorders in Indonesia is 59.3% per 1,000 live births. When compared to countries in Southeast Asia, Indonesia is still a country with a high prevalence of babies with congenital abnormalities. 50% of congenital abnormalities have no known cause; congenital abnormalities can be identified before birth, at birth, or later when the baby is born. Congenital abnormalities can affect organ shape, organ function, or both. Congenital abnormalities in infants vary from mild to severe and, in general, abnormalities occur in the first trimester phase, as happened in Ulutaue Village, there were some born with lobster claw syndrome, which they call stemmed fingers. This is a quite rare incident that occurs overseas only 1 in 90,000 live births, but it is different in Ulutaue Hamlet ranging from the elderly to children under five years old having fingers split in half, resemble crab claws. Most of the residents of Ulutaue Hamlet have suffered from this case. Reports in the last few years from the local health center found pregnant women giving birth with the same case. The purpose of this study is to determine the risk factors of pregnant women that cause the phenomenon of Lobster claw syndrome at Ulutaue Hamlet, Mare District, Bone Regency, South Sulawesi. This study uses a type of quantitative research with an analytical cross sectional design approach that aims at analyzing the relationship between risk factors of pregnant women and the occurrence of Lobster claw syndrome phenomenon. Keywords: Pregnant Women, Lobster Claw Syndrome.
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RAYCHAUDHURI, AMITAVA, and SREERUP RAYCHAUDHURI. "$B^0 - \bar B^0 $ MIXING IN A SUPERSYMMETRY-INSPIRED TWO HIGGS DOUBLET MODEL." Modern Physics Letters A 03, no. 11 (September 1988): 1099–105. http://dx.doi.org/10.1142/s0217732388001306.

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A supersymmetry-motivated two Higgs doublet model with equal vacuum expectation values for the two neutral Higgs and with a physical charged Higgs mass of 80–100 GeV is carefully examined in the context of its implications for [Formula: see text] mixing. Even with this conservative choice of Higgs parameters, the lower bound on the top quark mass coming from the ARGUS data is found to be considerably relaxed. An upper bound is also set, using results from CLEO and Mark II.
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47

Asner, David M. "$D^0 \bar{D}^0$ Quantum Correlations, Mixing, and Strong Phases." International Journal of Modern Physics A 21, no. 27 (October 30, 2006): 5456–59. http://dx.doi.org/10.1142/s0217751x06034604.

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Because of the quantum correlation between the pair-produced D0 and [Formula: see text] from the decay of the ψ(3770), the time-integrated single and double tag decay rates depend on charm mixing amplitudes, doubly-Cabibbo-suppressed amplitudes, and the relative strong phase δ between D0 and [Formula: see text] decays to identical final states. Using 281 pb-1 collected with the CLEO-c detector on the ψ(3770) resonance, we measure the absolute branching fractions of D0 decays to hadronic flavored states, CP eigenstates, and semileptonic final states to determine the relative strong phase cos δ and to limit the mixing amplitude y.
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48

Hewer, E., G. Panitz, J. Elsner, F. Swamy von Zastrow, K. Quint, J. Eschbacher, D. Sadeghi, et al. "P13.05.A Image annotation guideline for invivo confocal laser endomicroscopy, interrater reliability and how to learn from medical consensus for machine learning algorithms." Neuro-Oncology 24, Supplement_2 (September 1, 2022): ii81—ii82. http://dx.doi.org/10.1093/neuonc/noac174.285.

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Abstract Background Intraoperative confocal laser endomicroscopy (CLE) is an in vivo imaging technique increasingly studied in neurosurgery and neuropathology. It can be affected by artifacts introduced by the CLE device or related to the intraoperative setting. We developed and evaluated an image annotation guideline (AGL) to detect and eliminate images bearing no valuable information as a result of such artifacts. Images ware classified into good and bad quality, based on defined technical criteria, which are also considered relevant by clinical experts. Material and Methods Datasets were created from intraoperative CLE in vivo specimens of patients resected for brain tumors. The process from data collection to development of the ML algorithm followed 7 steps: data quality specification, image and metadata collection, AGL development, annotation, data allocation for clinical validation, clinical validation, and, optionally, algorithm development. Final diagnoses were obtained by pathological analysis. Artifacts were grouped into three categories: diminished signal-to-noise-ratio (dSNR), optical distortions (movement/perturbations), and contrast/brightness artifacts. Images were annotated by 4 medical data annotators (T4). For clinical validation, 500 images were excluded from the training data and additionally annotated by 3 board certified neuropathologists (NPs 1-3) with experience in CLE imaging, to determine the medical consensus on good and bad images. All raters (NPs) were compared against each other and against T4; T4 was also compared against the medical consensus. Cohen’s Kappa and overall percentage agreement (OPA) were used to evaluate inter-rater reliability. Positive percent agreement (PPA) and negative percentage agreement (NPA) were also used to evaluate agreement between medical consensus and T4. Results 21,616 CLE images and corresponding clinical metadata were collected from 94 patients and annotated. For each case between 27 and 815 CLE images were acquired over the course of the surgery (mean=175 images per case, SD=170.6). 11% and 13% of images were labeled as dSNR and distortion, respectively, and 34% as class contrast. 42% of the images represented the good quality images. Interrater agreement between the 3 NPs ranged between 0.30 and 0.59. Agreement between T4 and the medical consensus was substantial (Cohen’s Kappa &gt;=0.61). OPA between T4 and the medical consensus was 80.60%, PPA 72.34% and NPA 87.92%. Conclusion Annotations according to a well-structured and expertly curated AGL show higher values for Cohen’s Kappa and Overall Percent Agreement (OPA) with the medical consensus, than that of individual experts among one another. Such an AGL can be considered appropriate and produces on par results with annotations by a group of experts in the field and can be further employed for training machine learning (ML) algorithms.
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KIM, HYUNCHEOL, and YINUO CHEN. "The Evolution Mechanism of the Chinese Emerging Degree Adverb ‘Bao(爆)’s Meaning in Perspective of Cognitive Linguistics." Chinese Language Education and Research 32 (December 31, 2020): 375–403. http://dx.doi.org/10.24285/cler.2020.12.32.375.

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Liu, Na. "A Word-formation and Semantic and Cognitive Pragmatic Analysis on the Color Words of Chinese ‘Bai(白)’ and Korean ‘희다/하얗다’." Chinese Language Education and Research 32 (December 31, 2020): 329–52. http://dx.doi.org/10.24285/cler.2020.12.32.329.

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