Academic literature on the topic 'CJC'

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Journal articles on the topic "CJC"

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Davies, S. L., L. Martín, and R. M. Castañer. "CJC-1131." Drugs of the Future 30, no. 6 (2005): 553. http://dx.doi.org/10.1358/dof.2005.030.06.910208.

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Capligins, F., A. Litvinenko, A. Aboltins, E. Austrums, A. Rusins, and D. Pikulins. "Experimental Study of the Chaotic Jerk Circuit Application for Chaos Shift Keying." Latvian Journal of Physics and Technical Sciences 58, no. 4 (August 1, 2021): 55–68. http://dx.doi.org/10.2478/lpts-2021-0033.

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Abstract The paper presents a study of the chaotic jerk circuit (CJC) employment capabilities for digital communications. The concept of coherent chaos shift keying (CSK) communication system with controlled error feedback chaotic synchronization is proposed for a specific CJC in two modifications. The stability of chaotic synchronization between the two CJCs was evaluated in terms of voltage drop at the input of the slave circuit and the impact of channel noise using simulations and experimental studies.
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Teichman, Sam L., Ann Neale, Betty Lawrence, Catherine Gagnon, Jean-Paul Castaigne, and Lawrence A. Frohman. "Prolonged Stimulation of Growth Hormone (GH) and Insulin-Like Growth Factor I Secretion by CJC-1295, a Long-Acting Analog of GH-Releasing Hormone, in Healthy Adults." Journal of Clinical Endocrinology & Metabolism 91, no. 3 (March 1, 2006): 799–805. http://dx.doi.org/10.1210/jc.2005-1536.

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Abstract Context: Therapeutic use of GHRH to enhance GH secretion is limited by its short duration of action. Objective: The objective of this study was to examine the pharmacokinetic profile, pharmacodynamic effects, and safety of CJC-1295, a long-acting GHRH analog. Design: The study design was two randomized, placebo-controlled, double-blind, ascending dose trials with durations of 28 and 49 d. Setting: The study was performed at two investigational sites. Participants: Healthy subjects, ages 21–61 yr, were studied. Interventions: CJC-1295 or placebo was administered sc in one of four ascending single doses in the first study and in two or three weekly or biweekly doses in the second study. Main Outcome Measures: The main outcome measures were peak concentrations and area under the curve of GH and IGF-I; standard pharmacokinetic parameters were used for CJC-1295. Results: After a single injection of CJC-1295, there were dose-dependent increases in mean plasma GH concentrations by 2- to 10-fold for 6 d or more and in mean plasma IGF-I concentrations by 1.5- to 3-fold for 9–11 d. The estimated half-life of CJC-1295 was 5.8–8.1 d. After multiple CJC-1295 doses, mean IGF-I levels remained above baseline for up to 28 d. No serious adverse reactions were reported. Conclusions: Subcutaneous administration of CJC-1295 resulted in sustained, dose-dependent increases in GH and IGF-I levels in healthy adults and was safe and relatively well tolerated, particularly at doses of 30 or 60 μg/kg. There was evidence of a cumulative effect after multiple doses. These data support the potential utility of CJC-1295 as a therapeutic agent.
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Ruel, Guillaume, Sonia Pomerleau, Patrick Couture, Simone Lemieux, Benoît Lamarche, and Charles Couillard. "Favourable impact of low-calorie cranberry juice consumption on plasma HDL-cholesterol concentrations in men." British Journal of Nutrition 96, no. 2 (August 2006): 357–64. http://dx.doi.org/10.1079/bjn20061814.

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A low HDL-cholesterol concentration is an independent risk factor for CVD. Studies have suggested that flavonoid consumption may be cardioprotective, and a favourable impact on circulating HDL-cholesterol concentrations has been suggested to partially explain this association. The aim of the present study was to determine the effect of consuming increasing daily doses of low-calorie cranberry juice cocktail (CJC) on the plasma lipid profile of abdominally obese men. For that purpose, thirty men (mean age 51 (SD 10) years) consumed increasing doses of CJC during three successive periods of 4 weeks (125ml/d, 250ml/d, 500ml/d). Before the study and after each phase, we measured changes in physical and metabolic variables. We noted a significant increase in plasma HDL-cholesterol concentration after the consumption of 250ml CJC/d (+8·6±14·0% v. 0ml CJC/d; P<0·01), an effect that plateaued during the last phase of the study (500ml CJC/d: +8·1±10·0% v. 0ml CJC/d; P<0·0001). Multivariate analyses revealed that changes in plasma apo A-I (IR2=48%, P<0·0001) and triacylglycerol (R2=16%, P<0·005) concentrations were the only variables significantly contributing to the variation in plasma HDL-cholesterol concentration noted in response to the intervention. No variation was observed in total as well as in LDL and VLDL cholesterol. The present results show that daily CJC consumption is associated with an increase in plasma HDL-cholesterol concentrations in abdominally obese men. We hypothesise that polyphenolic compounds from cranberries may be responsible for this effect, supporting the notion that the consumption of flavonoid-rich foods can be cardioprotective.
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Alba, Maria, Danilo Fintini, Alessia Sagazio, Betty Lawrence, Jean-Paul Castaigne, Lawrence A. Frohman, and Roberto Salvatori. "Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse." American Journal of Physiology-Endocrinology and Metabolism 291, no. 6 (December 2006): E1290—E1294. http://dx.doi.org/10.1152/ajpendo.00201.2006.

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Although the majority of children with isolated growth hormone (GH) deficiency have a good growth response to GH-releasing hormone (GHRH), the use of this therapeutic agent is limited by its very short half-life. Indeed, we have shown that, in mice with GHRH gene ablation (GHRH knockout; GHRHKO), even twice-daily injections of a GHRH analog are unable to normalize growth. CJC-1295 is a synthetic GHRH analog that selectively and covalently binds to endogenous albumin after injection, thereby extending its half-life and duration of action. We report the effects of CJC-1295 administration in GHRHKO animals. Three groups of 1-wk-old GHRHKO mice were treated for 5 wk with 2 μg of CJC-1295 at intervals of 24, 48, and 72 h. Placebo-treated GHRHKO mice and mice heterozygous for the GHRHKO allele served as controls. GHRHKO animals receiving daily doses of CJC-1295 exhibited normal body weight and length. Mice treated every 48 and 72 h reached higher body weight and length than placebo-treated animals, without full growth normalization. Femur and tibia length remained normal in animals treated every 24 and 48 h. Relative lean mass and subcutaneous fat mass were normal in all treated groups. CJC-1295 caused an increase in total pituitary RNA and GH mRNA, suggesting that proliferation of somatotroph cells had occurred, as confirmed by immunohistochemistry images. These findings demonstrate that treatment with once-daily administration of CJC-1295 is able to maintain normal body composition and growth in GHRHKO mice. The same dose is less effective when administered every 48 or 72 h.
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Jetté, Lucie, Roger Léger, Karen Thibaudeau, Corinne Benquet, Martin Robitaille, Isabelle Pellerin, Véronique Paradis, Pieter van Wyk, Khan Pham, and Dominique P. Bridon. "Human Growth Hormone-Releasing Factor (hGRF)1–29-Albumin Bioconjugates Activate the GRF Receptor on the Anterior Pituitary in Rats: Identification of CJC-1295 as a Long-Lasting GRF Analog." Endocrinology 146, no. 7 (July 1, 2005): 3052–58. http://dx.doi.org/10.1210/en.2004-1286.

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Abstract In vivo bioconjugation to the free thiol on Cys34 of serum albumin by a strategically placed reactive group on a bioactive peptide is a useful tool to extend plasma half-life. Three maleimido derivates of human GH-releasing factor (hGRF)1–29 were synthesized and bioconjugated to human serum albumin ex vivo. All three human serum albumin conjugates showed enhanced in vitro stability against dipeptidylpeptidase-IV and were bioactive in a GH secretion assay in cultured rat anterior pituitary cells. When the maleimido derivatives were individually administered sc to normal male Sprague Dawley rats, an acute secretion of GH was measured in plasma. The best compound, CJC-1295, showed a 4-fold increase in GH area under the curve over a 2-h period compared with hGRF1–29. CJC-1295, a tetrasubstituted form of hGRF1–29 with an added Nε-3-maleimidopropionamide derivative of lysine at the C terminus, was selected for further pharmacokinetic evaluation, where it was found to be present in plasma beyond 72 h. A Western blot analysis of the plasma of a rat injected with CJC-1295 showed the presence of a CJC-1295 immunoreactive species on the band corresponding to serum albumin, appearing after 15 min and remaining in circulation beyond 24 h. These results led to the identification of CJC-1295 as a stable and active hGRF1–29 analog with an extended plasma half-life.
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Jakubczyk, Ewa, and Anna Kamińska-Dwórznicka. "Effect of Addition of Chokeberry Juice Concentrate and Foaming Agent on the Physical Properties of Agar Gel." Gels 7, no. 3 (September 10, 2021): 137. http://dx.doi.org/10.3390/gels7030137.

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This study aimed to determine the effect of the addition of chokeberry juice concentrate (CJC) and foaming agent (egg albumin) with different percentages on the selected physical properties of agar gel. The agar gels with the addition of 5, 10, and 20% concentrations of chokeberry juice concentrate and with fructose addition were prepared. In addition, the foamed gels with different concentrations of egg albumin (in the range 0.5–2.0%) and CJC were produced. The water content, colour, density, hold-up and some mechanical and TPA (Texture Profile Analysis) descriptors as well some structural and acoustic emission parameters of non-aerated and foamed gels were analysed. The addition of CJC changed the colour of agar gel with fructose, the attractive appearance of the aerated gel was also linked with the addition of concentrate. The addition of 20% of CJC and foaming agent created samples with very low hardness, cohesiveness, and gumminess, and the structure of the aerated samples was characterised by the larger bubble diameter and the wider distribution of their size. The more promising texture and structure properties were obtained for samples with aerated gels with 5 and 10% addition of chokeberry juice concentrate.
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Ionescu, Madalina, and Lawrence A. Frohman. "Pulsatile Secretion of Growth Hormone (GH) Persists during Continuous Stimulation by CJC-1295, a Long-Acting GH-Releasing Hormone Analog." Journal of Clinical Endocrinology & Metabolism 91, no. 12 (December 1, 2006): 4792–97. http://dx.doi.org/10.1210/jc.2006-1702.

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Abstract Context: Pulsatile GH secretion is considered important for many of the hormone’s physiological effects. Short-term GHRH infusions enhance GH pulsatility and increase IGF-I, but the short GHRH half-life limits its therapeutic use. A synthetic GHRH analog (CJC-1295) that binds permanently to endogenous albumin after injection (half-life = 8 d) stimulates GH and IGF-I secretion in several animal species and in normal human subjects and enhances growth in rats. Objective: Our objective was to assess GH pulsatility after a single injection of CJC-1295 and determine which GH secretion parameters correlated to the increase in IGF-I production. Methods: GH pulsatility was assessed by 20-min blood sampling during an overnight 12-h period in healthy 20- to 40-yr-old men before and 1 wk after injection of either 60 or 90 μg/kg CJC-1295. Results: GH secretion was increased after CJC-1295 administration with preserved pulsatility. The frequency and magnitude of GH secretory pulses were unaltered. However, basal (trough) GH levels were markedly increased (7.5-fold; P &lt; 0.0001) and contributed to an overall increase in GH secretion (mean GH levels, 46%; P &lt; 0.01) and IGF-I levels (45%; P &lt; 0.001). No significant differences were observed between the responses to the two drug doses. The IGF-I increases did not correlate with any parameters of GH secretion. Conclusions: CJC-1295 increased trough and mean GH secretion and IGF-I production with preserved GH pulsatility. The marked enhancement of trough GH levels by continuous GHRH stimulation implicates the importance of this effect on increasing IGF-I. Long-acting GHRH preparations may have clinical utility in patients with intact pituitary GH secretory capability.
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Camapum, Jaqueline Lustosa Rodrigues, Gardênia Alves da Silva, Cristian Francisco de Carvalho Pereira, Fabiane Leite da Silva, Nathália Castelo Branco Barros, Ana Paula Barros Fonseca, Nayara Kelen Miranda dos Santos, Vitória de Cássia Coelho Rodrigues, João Gabriel Melo Rodrigues, and Kátia Regina Ferreira Sousa. "Celulite juvenil canina em Dachshund: relato de caso." Revista Eletrônica Acervo Científico 8 (January 6, 2020): e2359. http://dx.doi.org/10.25248/reac.e2359.2020.

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Esse artigo relata um caso de Celulite Juvenil Canina (CJC) em um filhote da raça Dachshund na cidade de Teresina – PI, com tratamento responsivo, descrevendo sinais clínicos, abordagem clínica, terapia instituída e resposta do animal ao tratamento. Este apresentava histórico de otite crônica bilateral, com estenose em conduto esquerdo, secreção purulenta e crostas em todo o pavilhão auricular, dor, além de apatia, falta de apetite, vocalização e linfonodos submandibulares aumentados, sendo tratado para otite e, passados quatro dias, manifestou alopecia, despigmentação de lábios, focinho e região periocular, além de edema, crostas e pústulas nessa região, sugerindo CJC. Após diagnóstico clínico associado aos exames complementares, iniciou-se o tratamento imunossupressor e antibiótico, onde o animal apresentou remissão dos sintomas em 40 dias. O trabalho evidencia a ocorrência de CJC em filhote, bem como a importância do diagnóstico dessa doença para o devido tratamento e obtenção de cura do paciente.
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Menkis, Richard. "Jewish Communal Identity at the Crossroads: Early Jewish Responses to Canadian Multiculturalism, 1963-1965." Studies in Religion/Sciences Religieuses 40, no. 3 (June 27, 2011): 283–92. http://dx.doi.org/10.1177/0008429811408215.

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This article challenges the assumption that the Canadian Jewish community embraced the discourse and potential of multiculturalism rapidly and enthusiastically. It has been proven that certain groups—most notably the Ukrainians—used the hearings of the Royal Commission on Bilingualism and Biculturalism, which promised to consider the ‘‘contributions of the other ethnic’’ groups, to promote the idea that Canada is multicultural. But the largest organization of Canadian Jewry—the Canadian Jewish Congress (CJC)—was very cautious in its dealings with the Commission. It only participated in the Preliminary Hearings, in order to protest the preamble’s language that referred to the ‘‘two founding races. From the records of meetings, it is evident that CJC, based in Montreal—which was the home of the largest Jewish community in Canada at the time—was worried that introducing ‘‘multiculturalism’’ would offend the French. This article also asserts that CJC was not willing to define the Jews as an ethnic group, which was the implied category for groups in the new discourse of multiculturalism. CJC thought that a self-definition of the Jews as an ethnic group would weaken the place of Jews in Canadian society, both because of how Jews defined themselves on the census of 1961 and because they believed that they had a higher profile in the division of society into Protestant—Catholic—Jew than in a society divided into ethnic groups.
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Dissertations / Theses on the topic "CJC"

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Bukowski, Meike [Verfasser], Bernd [Akademischer Betreuer] Siebenhüner, and Ulrich [Akademischer Betreuer] Scheele. "Environmental conflicts and conservation justice (CJC) in marine protection : a CJC-analysis / Meike Bukowski ; Bernd Siebenhüner, Ulrich Scheele." Oldenburg : BIS der Universität Oldenburg, 2018. http://d-nb.info/1181325218/34.

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Bukowski, Meike Verfasser], Bernd [Akademischer Betreuer] [Siebenhüner, and Ulrich [Akademischer Betreuer] Scheele. "Environmental conflicts and conservation justice (CJC) in marine protection : a CJC-analysis / Meike Bukowski ; Bernd Siebenhüner, Ulrich Scheele." Oldenburg : BIS der Universität Oldenburg, 2018. http://nbn-resolving.de/urn:nbn:de:gbv:715-oops-40556.

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Badenes, Marina Martins. "In vivo evaluation of the role of Delta-like 4/Notch signaling in the development of intestinal tumors." Doctoral thesis, Universidade de Lisboa. Faculdade de Medicina Veterinária, 2016. http://hdl.handle.net/10400.5/11190.

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Tese de Doutoramento em Ciências Veterinárias, especialidade de Ciências Biológicas e Biomédicas
Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related death in the Western world. Dll4/Notch signaling has been shown to regulate tumor angiogenesis and cancer stem cell maintenance in CRC, but how it affects the intestinal precancerous lesions that lead to CRC initiation is not known. Therefore we evaluated the role of Dll4/Notch pathway during intestinal tumorigenesis. For that we used two well-established mouse models of CRC, the ApcMin/+ autochthonous transgenic model and the azoxymethane plus dextran sodium sulphate chemically induced model of chronic colitis associated-cancer (CAC). First we analyzed the protein expression pattern of Dll4 and other Notch pathway members in these settings relatively to that in the normal gut. Then we evaluated the effect of endothelial-specific or ubiquitous Dll4 deregulation and performed a therapeutic trial with the Dll4 inhibitor Dll4-Fc. This protein was administered alone, and in combination with the epidermal growth factor receptor (EGFR)-specific tyrosine kinase inhibitor erlotinib to assess if the anti-Dll4 therapy mediated vascular defects impaired the delivery of other anti-cancer drugs to the tumors. We observed that the Notch pathway is activated in the two studied models of CRC. The normal protein expression pattern of Notch pathway members in the gut is altered in chronic colitis and in ApcMin/+ and colitis-driven intestinal tumors. Dll4 is the most upregulated ligand in the intestinal adenomas in both models of CRC and is present in both tumor epithelium and stroma. Both Dll4 blockade (endothelial-specific and ubiquitously) and activation (endothelial-specific) have an inhibitory effect on intestinal tumor initiation and growth by promoting a noncompetent vasculature or decreasing the vessel density, respectively. Besides its angiogenic related effects, Dll4/Notch pathway promotes excessive inflammation in CAC, sustains the tumor stem cell pool and tumor proliferation synergistically with Wnt signaling, and inhibits differentiation mainly of the secretory cells. In addition, the effectiveness of erlotinib is not affected by Dll4-Fc, where these therapies additively inhibit intestinal tumorigenesis.
RESUMO - Avaliação in vivo da função da sinalização intercelular Dll4/Notch no desenvolvimento de tumores intestinais - O cancro colo-rectal (CCR) é o terceiro tipo de cancro mais comum e é uma das principais causas de morte no Mundo Ocidental. O CCR geralmente desenvolve-se esporadicamente, mas também pode ser hereditário como na síndrome polipose adenomatosa familiar (PAF). A PAF está associada à ativação da via de sinalização Wnt através de mutações no gene supressor tumoral Adenomatous Polyposis Coli (APC), que também ocorre frequentemente nos CCR esporádicos. O desenvolvimento do CCR também pode estar associado a inflamação crónica, nomeadamente à doença de Crohn (CD) e à colite ulcerativa (UC). Infelizmente o desenvolvimento de novas estratégias terapêuticas ou preventivas que tenham como alvo vias de sinalização críticas no desenvolvimento do CCR continua a ser extremamente necessário. Uma dessas estratégias tem como alvo a angiogénese tumoral. O primeiro agente anti-angiogénico a ser aprovado foi o Bevacizumab, que é usado em combinação com outros fármacos no tratamento do CCR metastático. No entanto, a utilização deste fármaco leva ao aparecimento de efeitos secundários e resistência tumoral e em tumores não metastáticos não se tem mostrado eficaz. Assim, continua a ser necessário desenvolver melhores estratégias terapêuticas anti-angiogénicas...
Centro de Investigação Interdisciplinar em Sanidade Animal (CIISA) e União Europeia: Fundo Social Europeu
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Ede, Andrew, and andrew ede@premiers qld gov au. "The Prevention of Police Corruption and Misconduct: A Criminological Analysis of Complaints Against Police." Griffith University. School of Criminology and Criminal Justice, 2000. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20030102.114721.

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The reform measures recommended by the Commission of Inquiry into Possible Illegal Activities and Associated Police Misconduct (referred to as the "Fitzgerald Inquiry") radically transformed the face of policing in Queensland. The most significant of these recommendations was the establishment of an external oversight body, the Criminal Justice Commission (CJC), which has independence from executive government and holds the power to investigate not only police but any public servant or politician. Other recommendations included "Whistleblower" legislation, increasing sanctions for serious misconduct, lateral recruitment and promotion by merit rather than seniority. The first main research question tested in this thesis is whether these reform measures have produced improvements in the following areas: the efficiency and effectiveness of the processes for dealing with complaints against police; public confidence in those processes and the public standing of the Queensland Police Service (QPS) generally; standards of police behaviour; the incidence of corrupt conduct; and police attitudes towards reporting misconduct by their fellow officers. These Fitzgerald Inquiry reforms were strategies primarily derived from two schools of thought describing the nature and cause of police corruption: deterrence based theory (including "individual" or "rotten apple" theory) and cultural (also labeled "cultural" or "socialisation") based theory. To date most strategies used to combat police corruption have been underpinned by these theories. A third theory - situational based theory (sometimes titled "environmental" or "opportunity" theory) - which has had success in crime prevention, has been scarcely used in the area of police corruption. However, an extensive body of research has affirmed the effects of situational factors on police behaviour, suggesting the potential for the application of situational crime prevention initiatives in combatting police corruption. The second research question proposed in this thesis is whether situational based theory could also be beneficial in the prevention of police corruption. Data drawn upon to test the first research question were interviews and surveys with police officers, public attitude surveys and statistics from the processing of complaints against police. Although each source has limitations, collectively the data are sufficiently comprehensive - and robust - to defend conclusions about the general direction of the changes which have occurred. These data indicate that the Fitzgerald Inquiry reforms have, at least to some degree, had their intended impact on the QPS. These reforms have contributed to an apparent improvement in public confidence in the complaints system and the QPS generally. Moreover, the available evidence suggests that the Fitzgerald Inquiry reforms have resulted in a weakening of the police code of silence. As far as the specific issue of corruption in the QPS is concerned, it is difficult to draw firm conclusions from existing data sources. However, the weight of the available evidence is that such conduct is less pervasive and occurs at lower levels than was the case in the pre-Fitzgerald Inquiry QPS. It is very difficult to ascertain which reform components were the most effective and which were not helpful at all, as these reform measures were initiated simultaneously. For example, the negative elements of the police culture may have been eliminated or reduced but whether it was the cultural strategies or one of the deterrence based strategies influencing officer behaviour remains unknown. The second main research question the thesis poses is that the use of situational crime prevention techniques has potential for contributing to the prevention of police corruption. A situational analysis of complaints against police data, including the development of a typology for classifying types of police corruption and misconduct, was used as an example of how this may be accomplished in Queensland. The study provides some, albeit limited, support for the hypothesis that situational crime prevention methods are applicable to police corruption. Based upon three years of complaints data, enough homogenous cases were gathered to enable the analysis of four categories of police corruption - Opportunistic Thefts, Driving under the Influence, Assault (while off-duty), and Theft from Employer. Given that this study only used three years of complaints data held by the CJC and more than nine years of data exist, productive situational analyses of many other categories of corruption is probable. This study also illustrated that complaints against police data are being under utilised by the QPS and the CJC. For future research in the situational analysis of complaints data, I recommend improving the gathering of data from complaints files for storage in electronic form to enable situational prevention analysis to be conducted more readily. A geographical example was used to illustrate further how complaints against police data could be more extensively utilised as a prevention tool. This analysis was conducted at an organisation unit level determined primarily by geographical factors. The complaint patterns of units of similar "task environments", as measured by unit size and type of duties performed, were compared in an attempt to identify those units experiencing the presence or absence of "bad apples" or a "negative culture". This study led to the conclusion that a divisional analysis of complaints data can provide information valuable in combatting police corruption. When task environment was held constant, it was possible to identify units experiencing the effects of possible "bad apples" and/or "negative cultures". Once these particular units were identified, intervention strategies to address the units' particular problem could be constructed. Future research in this area would involve ongoing divisional data analysis followed-up by individual assessment of officers identified as "bad apples", or a "compare-and-contrast" procedure to distinguish features requiring correction in units identified as having a "negative culture". The research findings presented in this thesis are that progress has occurred in a number of areas in addressing the problems identified by the Fitzgerald Inquiry, but that there is undoubtedly scope for more to be achieved. Despite the very significant increase in the resources and powers available to investigators post-Fitzgerald, it is still difficult to prove that a police officer engaged in misconduct, or that other officers were aware of this fact and had failed to take action, because of the constraints imposed by evidentiary and legal requirements. Thus, while it is vital to maintain an effective and credible independent complaints investigation system and ensure that there is a proper internal discipline process in place, the scope for increasing the "deterrent power" of the present system is limited. Putting more resources into complaints investigations might make a difference at the margins, but is unlikely to lead to a significant increase in the probability of a complaint being substantiated and a sanction imposed. Investing more resources in investigations has an additional cost in that such resources are then lost to other efforts to combat corruption that may provide more fruitful results in the long term. The value of an occasional substantiation is placed above the ability to engage in a large amount of prevention work. Inevitably then, three clear messages are apparent. First, continued effort must be made to modify the organisational climate of the QPS in terms of commitment to integrity. Recommended strategies to accomplish this end are to continue the recruitment of more educated, female and older officers to reduce police-citizen conflict and the negative elements of the police culture, and also to develop a comprehensive, integrated approach to ethics education for QPS officers at all ranks and positions. Second, other forms of deterrence against misconduct are needed such as the use of covert strategies like integrity testing which could be conducted in conjunction with the CJC. Third, a greater emphasis needs to be placed on developing and implementing preventive strategies. This thesis has shown that valuable prevention strategies can be gained from situational and divisional analysis of complaints data, and a range of proactive management options based upon situational crime prevention theory are recommended. These strategies have application in any police service.
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Rezai, Armon. "Demand and distribution in integrated economies." Oxford University Press, 2014. http://dx.doi.org/10.1093/cje/beu060.

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Aggregate demand is influenced by the functional income distribution of an economy and that of its trading partners. This relationship between income distribution and output is analyzed in a short-run two-country Neo-Kaleckian model. The effects of devaluation and redistribution are discussed in detail. Trade and redistribution within one country interact and output increases or decreases with changes in either depending on the specific distributional and exchange rate movements. The Marshall-Lerner condition is shown to be equivalent to the assumption of expansionary devaluation. If devaluation increases output, national redistribution policy toward wage earners is also more likely to be expansionary. (author's abstract)
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Coimbra, Daniel Fernando. "Natureza da ligação Ru-NO em novos nitrosilo complexos de rutênio com ligantes quelantes CCC e CNC contendo carbenos." reponame:Repositório Institucional da UFSC, 2015. https://repositorio.ufsc.br/xmlui/handle/123456789/136460.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2015.
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Compostos capazes de liberar ou sequestrar óxido nítrico são promissores agentes terapêuticos como antimicrobianos, reguladores da pressão sanguínea, no combate ao câncer, dentre outros. Neste trabalho foram investigados novos nitrosilo complexos de rutênio, potencialmente liberadores de óxido nítrico, contendo ligantes pinça quelantes tridentados em que dois sítios coordenantes são carbenos N heterociclos ligados por uma ponte fenila ou piridil que também coordena-se ao centro metálico. Derivados destes complexos são obtidos pela substituição de grupos alquila no átomo de nitrogênio dos grupos imidazolilideno. A estrutura geométrica e eletrônica destes complexos organometálicos e de seus produtos de redução monoeletrônica foram investigadas por métodos computacionais empregando-se a Teoria do Funcional da Densidade (DFT). A natureza da ligação química Ru NO foi estudada utilizando-se as técnicas de Análise de Decomposição de Energia de Su-Li (Su-Li EDA) e Orbitais Naturais de Ligação (NBO). Neste trabalho também foi avaliada uma metodologia para a predição de potenciais de redução dos nitrosilo complexos de rutênio estudados.

Abstract : Compounds capable of releasing or scavenging nitric oxide are promising therapeutic agents as antimicrobials, blood pressure regulators, in cancer treatment and many others. In this work were investigated new ruthenium nitrosyl complexes, potentially capable of releasing nitric oxide, containing chelating tridentade pincer ligands in which two coordinating sites are N-heterocyclic carbenes united by a bridging coordinating phenyl or pyridyl unit. Derivatives of these complexes are obtained by substitution of alkyl groups at the imidazolylidene nitrogen. The geometric and electronic structure of these organometallic complexes and their one-electron reduction products were investigated by computational methods employing Density Functional Theory. The nature of the Ru NO chemical bond was investigated using the Energy Decomposition Analysis of Su-Li and Natural Bond Orbitals. In this work it was also evaluated a methodology for the prediction of reduction potentials of the ruthenium nitrosyl complexes under investigation.
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Coupar, Sally-Anne. "The chronology and development of the coinage of Corinth to the Peloponnesian War." Thesis, University of Glasgow, 2000. http://theses.gla.ac.uk/2557/.

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This study's objective is to elucidate the numismatic history of the city of Corinth from the inception of the coinage to the beginning of the Peloponnesian War in 431BC. The method used in pursuit of the objective was to carry out a comprehensive die study which collected and analysed all known Corinthian dies with curved wing Pegasus type. Hoard and overstrike evidence was used to help order the sequence of the dies, as was the stylistic development. The numismatic, historical and archaeological evidence provided key dates which anchored the sequence and allowed the chronology of the coinage of Corinth to be revealed. The results of this study show that Corinth was one of the earliest Greek cities to issue coins. The silver necessary for the coinage was obtained from the coins of other cities and probably also from mines in the Thrace and Macedonian area. The main mint of Corinth was supplemented by an auxiliary mint at times and it also provided either dies or coins for Corinthian colonies. This study's conclusions indicate that the output from the Corinthian mint was sustained and prolific, and participation in the Corinthian economy was rigorously controlled by the city authorities. This study has also shown that the only evidence for a break in activity at the Corinthian mint is in the mid 450's BC, and that the operation of the mint was not affected by the outbreak of the Peloponnesian War.
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Kandaskalov, Dmytro. "Etude théorique de défauts ponctuels et complexes dans les métaux : application au fer-cc et nickel-cfc." Thesis, Toulouse, INPT, 2013. http://www.theses.fr/2013INPT0007/document.

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L’étude des défauts ponctuels (lacunes, impuretés) et des complexes (cavités, joints de grains, etc.) est un domaine important de la physique du solide. Les propriétés physiques et chimiques des matériaux (élasticité, plasticité, fragilité, etc.) sont très souvent corrélées à la présence de ces défauts. Les techniques expérimentales ne sont cependant pas toujours en mesure de fournir une compréhension suffisante de ceux-ci. Dans ce cas-là, les simulations numériques et la modélisation à l’échelle atomique sont des outils utiles pour interpréter les résultats expérimentaux. Mon travail de thèse se situe dans ce cadre. Le manuscrit comporte 4 principales parties. Dans la première et la deuxième partie, nous présentons les principes de la DFT et la méthodologie utilisée dans cette thèse. La troisième partie de ce manuscrit résume l’étude théorique par DFT de la formation, la migration et la diffusion de différentes configurations de multi-lacunes Vn(n=1-15) dans le fer cubique centré. Les configurations de Vn les plus stables y sont décrites en détail : les énergies de formation, de liaison et de piégeage. La migration de différentes multilacunes est discutée en détail d’un point de vue énergétique et configurationnelle. Dans la dernière partie, nous nous intéressons à l’absorption du soufre dans différents sites (interstitiel et substitutionnel) du massif de Ni et sa ségrégation vers les surfaces Ni (100) et Ni (111). L’étude du soufre en volume permet de clarifie sa position en solution solide. Nous discutons des interactions soufre-soufre et avec le métal de base. La ségrégation et l’absorption sur des surfaces libres du nickel est aussi abordée en détail
The study of point defects (vacancies, impurity) and complex defects (cavities, grain boundary etc.) is a major challenge for solid state physics. The physical and chemical properties of materials (such elasticity, plasticity, embrittlement etc.) are correlated to the presence of these defects. The experimental study is not always able to bring sufficient information about them. In this way computational simulations and the modeling on the atomic level is efficient to interpret the experimental results and to obtain new informations. This PhD work consists also in a theoretical study of defects in metals. This manuscript is organized in four main parts. In the first and second part, we present the theoretical principles and the methodology used in this work. In the third part, we report a long discussion on the study of formation, migration and diffusion of multivacancies Vn in the bcc-iron system. The main objective of this study is to identify and to analyze most stable configurations of multivacancies for different sizes of Vn (n=1-15) in Fe. The migration is also investigated. In the last part, we present a study of S atoms in nickel. The different sites (interstitial and substitutional sites) in solid solution of nickel-fcc and the segregation of sulfur on and in the Ni(100) and Ni(111) surfaces are discussed. The study of sulfur in the bulk shows that the atoms S occupy the substitutional sites. The S-S and S-Ni interactions are also presented. We conclude by a discussion on the segregation and the adsorption on free surfaces
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Cima, Franciele Fatima. "Capacidade de combinação de genitores, parâmetros genéticos de aparência e de rendimento de tubérculos e características de qualidade funcional e industrial de clones de batata." Universidade Federal de Pelotas, 2018. http://guaiaca.ufpel.edu.br:8080/handle/prefix/4111.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
Batatas com polpa colorida contêm altas concentrações de antioxidantes, incluindo ácidos fenólicos, antocianinas e carotenoides. Esses fitoquímicos apresentam efeitos terapêuticos e promotores da saúde humana, exercendo papel-chave na prevenção e/ou tratamento de doenças crônicas. O crescente interesse nos benefícios à saúde adquiridos através da alimentação tem contribuído para o aumento do consumo dessas batatas “especiais” e crescimento de um mercado especializado. Para atender a demanda desse nicho de mercado é imprescindível o desenvolvimento de cultivares de polpa colorida e, para o rápido progresso, é fundamental a escolha correta dos genitores e procedimentos eficientes de seleção. Nesse sentido, foram desenvolvidos três estudos. O primeiro visou estimar capacidade de combinação de clones de batata de polpa colorida e de polpa creme e amarelo claro para caracteres de aparência externa e interna e de rendimento de tubérculos. Foram avaliadas oito famílias segregantes de batata, em modelo de dialelo parcial (3x3). Verificou-se que há predomínio de efeitos aditivos de genes no controle de caracteres de aparência e de rendimento de tubérculos. O segundo estudo visou estimar parâmetros genéticos de caracteres de aparência externa e interna e de rendimento de tubérculos, e suas implicações na seleção, em uma população híbrida constituída de 12 famílias segregantes para cor da polpa. Os resultados sugerem que pode se aplicar forte pressão de seleção para os caracteres cor da película, cor predominante da polpa, cor secundária da polpa e distribuição da cor secundária, e seleção leve a moderada para profundidade de gemas, formato e aparência geral de tubérculo, na primeira geração clonal. O terceiro estudo visou caracterizar 12 clones de batata de polpa colorida quanto à concentração de compostos bioativos, caracteres de qualidade industrial e de rendimento de tubérculos. Os clones C2715-01-09, C2721-22-09 e C2743-01-09 apresentam elevadas concentrações de compostos bioativos e alta capacidade antioxidante, além de boas características de qualidade de processamento e bom potencial produtivo. O clone C2743-09-09 é o mais produtivo e possui atributos para fritura, porém apresenta teores mais baixos de compostos bioativos e atividade antioxidante mediana.
Colored fleshed potatoes contain high concentrations of antioxidants, including phenolic acids, anthocyanins and carotenoids. These phytochemicals have therapeutic effects and promoters of human health, playing a key role in the prevention and/or treatment of chronic diseases. The growing interest in the health benefits acquired through food has contributed to increase consumption of these "special" potatoes and growth of a specialized market. In order to meet the demand of this market niche, the development of colored fleshed varieties is essential, and for a fast progress it is fundamental the correct parental choice and efficient selection procedures. In this sense, three studies were developed. The first aimed to estimate combining ability of colored fleshed and cream and light yellow fleshed potato clones in the external and internal tuber appearance, and tuber yield. Eight segregating potato families were evaluated using a partial diallel design (3x3). It was verified that there is a predominance of additive effects of genes in the control of tuber appearance and yield traits. The second study aimed to estimate genetic parameters of tuber external and internal appearance and yield traits, and their implications on selection, in a hybrid population consisting of 12 segregating families for flesh color. The results suggest that a high pressure of selection can be applied to the traits color of the skin, predominant color of the flesh, secondary color of the flesh and distribution of secondary color, and mild to moderate selection for bud depth, shape and overall appearance of tuber, in the first clonal generation. The third study aimed to characterize 12 colored flesh potato clones as to the concentration of bioactive compounds, processing quality traits and tuber yield. Clones C2715-01-09, C2721-22-09 and C2743-01-09 present high concentrations of bioactive compounds and high antioxidant capacity, besides good processing quality traits and good yield potential. The clone C2743-09-09 is the most productive and has frying attributes, but presents lower levels of bioactive compounds, and medium antioxidant activity.
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Machado, Gilmara de Oliveira. "Preparação e caracterização de CMC e CMC graftizada." Universidade de São Paulo, 2000. http://www.teses.usp.br/teses/disponiveis/88/88131/tde-11092001-160555/.

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Polpa celulósica, para obtenção de carboximetilcelulose (CMC), foi obtida a partir do bagaço de cana-de-açúcar através de separação do material em fração fibrosa e medula, sua pré-hidrólise, posterior polpação soda/antraquinona e etanol/água. A polpa soda/antraquinona da fração fibra foi submetida ao processo de branqueamento para obter um material rico em celulose de alta pureza. A polpa branqueada da fração fibra foi utilizada na preparação da CMC na forma de sal de sódio e lítio. Para reações de enxertia foram utilizadas amostras de CMC preparadas no laboratório e comerciais usando isocianatos comerciais e sintetizados. Tanto a CMC como a CMC enxertada foram caracterizadas através de análises térmicas (DSC, TGA), espectroscopia no infravermelho (IV), ressonância magnética nuclear de carbono 13 (RMN 13C) e por microscopia eletrônica de varredura (MEV) e Espectroscopia Dispersiva de Raios-X (EDX). A análise detalhada dos espectros de IV e RMN 13C indica a formação de ligações uretanas em diferentes números de onda e deslocamentos químicos dependendo da CMC e isocianato utilizado. Também observa-se uma pequena mudança na linha de base da curva de DSC indicando uma possível transição vítrea da CMC que diminui após a enxertia da CMC com isocianato. Micrografias de MEV mostraram mudanças estruturais com as reações e a análise através de (EDX) um aumento no teor de carbono e diminuição no de oxigênio com as graftizações. Medidas de condutividade demonstraram que a NaCMC graftizada com isocianato de poli(óxido de propileno) apresenta condutividade de 10-5 S/cm a 100oC, comparável com outros eletrólitos sólidos poliméricos
The cellulosic pulp obtained from sugar cane bagasse was used to synthesize carboxymethylcellulose (CMC), the substrate for the grafting reactions with mono and di-isocyanathes. The sugar cane bagasse was separated into fiber and non-fiber fractions that then were submitted to the pre-hydrolyses and pulping reactions (sodium hydroxide/anthraquinone and ethanol/water). After that the sodium hydroxide/anthraquinone pulp of the fiber fraction was bleached to obtain a high purity cellulosic material. This cellulose was used to obtain the sodium and lithium salts of CMC (NaCMC and LiCMC respectively). Then these samples were used for grafting reactions with commercial octadecylisocyanate and hexamethylene-diisocyanate and synthesized monoisocyanate of poly(propylene oxide). All the samples were characterized through thermal analyses (DSC/TGA), infra-red spectroscopy (IR), solid state 13C nuclear magnetic resonance (13C-NMR), scanning electron microscopy (SEM) and X-ray diffraction (XRD). The thermal analysis indicate a possible glass transition of CMC at about 65oC that decreases for to about 29oC after the grafting reaction with isocyanate. The micrographs show structural changes occurred during the several reactions confirmed by thermal analysis. The detailed analysis of IR and NMR 13C spectra of grafted samples indicated the formation of urethane bonds. Conductivity measurements of NaCMC grafted with the poly(propylene oxide) isocyanate gave the value of 10-5 S/cm at 100oC that is comparable with other polymeric solid electrolytes.
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Books on the topic "CJC"

1

Committee, Chartered Institute of Public Finance and Accountancy Competitiveness Joint. The CJC guide to partnerships & partnering. London: Chartered Institute of Public Finance and Accountancy, Competitiveness Joint Committee, 2001.

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Marinoni, Luiz Guilherme. Tutela específica: Arts. 461, CPC e 84, CDC. São Paulo, SP, Brasil: Editora Revista dos Tribunais, 2000.

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Williams, Tyrone. C.c. San Francisco, Calif: Krupskaya, 2002.

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Tutela relativa aos deveres de fazer e de não fazer: CPC, art. 461, CDC, art. 84. São Paulo: Editora Revista dos Tribunais, 2001.

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Quốc, Nguyễn Hưng. Tho̕ con cóc và những vấn đề kh́ac: The "con coc" poem and other literary issues. Gardena, Calif: Văn Mới in association with Trung Tâm Liên Mạng Tiền Vệ, 2006.

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CNC machining. Tinley Park, Ill: The Goodheart-Willcox Company, 2008.

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Mackenzie, Molly. CCC Inc. Haarlem: In de Knipscheer, 2007.

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Coach Drivers Club of Great Britain. CDC yearbook. Yate: CDC, 1999.

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1944-, Hart Richard, ed. CXC chemistry. Oxford: Oxford University Press, 1985.

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Russell, Roberts. C.C. Sabathia. Hockessin, Del: Mitchell Lane Publishers, 2012.

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Book chapters on the topic "CJC"

1

Carpenter, Steven. "Integration of CTC into a CRC Screening Program." In Colorectal Cancer Screening and Computerized Tomographic Colonography, 115–26. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-5943-9_6.

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Gooch, Jan W. "CHC." In Encyclopedic Dictionary of Polymers, 136. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_2231.

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Gooch, Jan W. "CMC." In Encyclopedic Dictionary of Polymers, 148. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_2471.

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Steele, Guy L., Xiaowei Shen, Josep Torrellas, Mark Tuckerman, Eric J. Bohm, Laxmikant V. Kalé, Glenn Martyna, et al. "CnC." In Encyclopedia of Parallel Computing, 304. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-0-387-09766-4_2293.

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Peters, Nils, Martin Dichgans, Sankar Surendran, Josep M. Argilés, Francisco J. López-Soriano, Sílvia Busquets, Klaus Dittmann, et al. "CNC." In Encyclopedia of Molecular Mechanisms of Disease, 372. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_7411.

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Peters, Nils, Martin Dichgans, Sankar Surendran, Josep M. Argilés, Francisco J. López-Soriano, Sílvia Busquets, Klaus Dittmann, et al. "CJD." In Encyclopedia of Molecular Mechanisms of Disease, 362. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_8506.

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Peters, Nils, Martin Dichgans, Sankar Surendran, Josep M. Argilés, Francisco J. López-Soriano, Sílvia Busquets, Klaus Dittmann, et al. "CRC." In Encyclopedia of Molecular Mechanisms of Disease, 460. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_7836.

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Hubert, Jane, Karen Plé, Mahmoud Hamzaoui, and Jean-Hugues Renault. "Polyphenol Purification by Solid Support-Free Liquid–Liquid Chromatography (CCC, CPC)." In Natural Products, 2145–72. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-22144-6_189.

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Batelaan, J. G., C. G. Ginkel, and F. Balk. "Carboxymethylcellulose (CMC)." In Detergents, 329–36. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-540-47108-0_11.

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Böge, Alfred. "CNC-Technik." In Technologie/Technik Formelsammlung, 91–93. Wiesbaden: Vieweg+Teubner Verlag, 2001. http://dx.doi.org/10.1007/978-3-663-11607-3_7.

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Conference papers on the topic "CJC"

1

Liu, Xiping, Sean Hong, Shijuan Wu, Zhiwen Yao, and Qiang Xie. "Abstract 1990: Cjc-1134-pc, a long-acting glp-1r agonist, effects in modulating pro-inflammatory cytokines in the tumor environment." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-1990.

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Liu, Xiping, Sean Hong, Shijuan Wu, Zhiwen Yao, and Qiang Xie. "Abstract 1990: Cjc-1134-pc, a long-acting glp-1r agonist, effects in modulating pro-inflammatory cytokines in the tumor environment." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-1990.

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Liu, Bing, Xiao Tan, Dinaer Bolati, Hang An, and Jinxu Jiang. "Axial Compressive Loading Capacity of Pressurized Energy Pipeline With Corrosion Defects." In 2020 13th International Pipeline Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/ipc2020-9616.

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Abstract Corrosion defects are dreadfully damaging to the stability of pipelines. Using the finite element (FE) simulation method, a model of API 5L X65 steel pipeline is established in this work to study its buckling behavior subjected to axial compressive loading. The local buckling state of the pipe at the ultimate axial compressive capacity was captured. Compared with the global compressive strain capacity (CSCglobal), the local compressive strain capacity (CSClocal) is more conservative. Extensive parametric analysis, including approximately 115 FE cases, was conducted to study the influence of the corrosion defect sizes and internal pressure on the corroded pipe’s compressive loading capacity (CLC) and CSC. Results show that the enlarged size of the corrosion defect decreases both the CLC and the CSC of the pipeline, but the CLC almost keeps unchanged as the length of corrosion defects increases. The CLC decreases with the increase of the length of corrosion defects when the length is less than 1.5Dt and greater than 0.7Dt. The CSC drops significantly until the length of the corrosion defect reached 1.8Dt. The deeper the corrosion defect, the smaller the CLC and the CSC. An increase in the width of corrosion defects tends to correspond to a decrease in the CLC and the CSC. With the increase of internal pressure, the CSC of the pipe gets greater while the CLC gets smaller. Based on the 115 FE results, a machine learning model based on support vector regression theory was developed to predict the pipe’s CSC. The regression coefficient between SVR predicted value and FEM actual value is 98.87%, which proves that the SVR model can predict the CSC with high accuracy and efficiency.
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Thiago Vieira da Silva, Pedro Henrique de Oliveira Adami, José Carlos de Oliveira, and Paulo Marcio da Silveira. "Avaliação comparativa do desempenho dinâmico de arranjos de transmissão CC com topologias CSC-LCC e CSC-CCC através do simulador RTDS." In VI Simpósio Brasileiro de Sistemas Elétricos. Natal, Rio Grande do Norte, Brasil: Grupo de Pesquisa Otimização e Supervisão de Sistemas Elétricos Industriais – OSSEI, 2015. http://dx.doi.org/10.20906/cps/sbse2016-0274.

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Costantino, Michael C., Thomas W. Houston, and Andrew S. Maham. "Development of Acceptance Criteria for Soil-Structure Interaction Solutions Using Linear SSI Techniques." In ASME 2016 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/pvp2016-63682.

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Seismic analysis and design of high-hazard nuclear facilities requires evaluation of soil-structure interaction (SSI) effects on structure and soil response due to earthquake ground motions. The industry-wide methodology of computing SSI response of buildings is through linear SSI techniques using the computer code SASSI. Technical issues were identified by users and regulators (Ref. 1) resulting in the U.S. Department of Energy (DOE) commissioning a large scale, multi-year Validation and Verification (V&V) Project for SASSI (Ref. 2). The project was a highly peer reviewed process that included an esteemed Participatory Peer Review Team, DOE oversight, as well as regulatory and stakeholder input. The project goal was to develop benchmark SSI solutions for the range of SSI problems associated with high-hazard facilities within the DOE complex. As per industry software quality control requirements, an acceptance limit for the benchmark solutions must be provided to define the acceptable accuracy of the results produced by SASSI relative to the benchmark. In order to define this limit, variation in the solution of foundation impedance must be related to an expected level of accuracy in structural design quantities of interest (e.g., response spectra, base shear, etc.). Therefore, extensive parametric analyses were performed for coupled soil-structure systems having a broad range of SSI parameters defined by foundation size, soil properties, building stiffness and mass properties, building height, etc. Based on the results of the parametric analyses, ASCE 4 code guidance, and engineering judgment of CJC&A and the peer review team, an acceptable level of accuracy in computed foundation impedance was determined for SASSI solutions. This supported the successful qualification of SASSI for use in two large-scale DOE projects.
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Noskievicova, Darja, Miroslav Mahdal, and Katerina Brodecka. "SW support for CCC and CQC control charts." In 2014 15th International Carpathian Control Conference (ICCC). IEEE, 2014. http://dx.doi.org/10.1109/carpathiancc.2014.6843633.

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Talnikar, Chaitanya, Tatiana Likhomanenko, Ronan Collobert, and Gabriel Synnaeve. "Joint Masked CPC And CTC Training For ASR." In ICASSP 2021 - 2021 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP). IEEE, 2021. http://dx.doi.org/10.1109/icassp39728.2021.9414227.

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Rong, Gao. "Study on Driver Program of CTC Based on CNC." In 2010 2nd International Conference on Intelligent Human-Machine Systems and Cybernetics (IHMSC). IEEE, 2010. http://dx.doi.org/10.1109/ihmsc.2010.57.

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Wee, Lo Chea, Tan Sze Yee, Gan Sue Yin, and Goh Cin Sheng. "Investigation of Die Tilting of Packages with Single and Multi-chips." In ISTFA 2018. ASM International, 2018. http://dx.doi.org/10.31399/asm.cp.istfa2018p0429.

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Abstract Advanced package technology often includes multi-chips in one package to accommodate the technology demand on size & functionality. Die tilting leads to poor device performance for all kinds of multi-chip packages such as chip by chip (CbC), chip on chip (CoC), and the package with both CbC and CoC. Traditional die tilting measured by optical microscopy and scanning electron microscopy has capability issue due to wave or electron beam blocking at area of interest by electronic components nearby. In this paper, the feasibility of using profilemeter to investigate die tilting in single and multi-chips is demonstrated. Our results validate that the profilemeter is the most profound metrology for die tilting analysis especially on multi-chip packages, and can achieve an accuracy of &lt;2μm comparable to SEM.
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10

Mulligan, Phillip, Catherine Johnson, Jason Ho, Cody Lough, and Edward Kinzel. "3D Printed Conical Shaped Charge Performance." In 2019 15th Hypervelocity Impact Symposium. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/hvis2019-110.

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Abstract A Conical Shaped Charge (CSC) is a versatile device utilized in construction, mining, petroleum and defense industries. The geometry and material structure of the metal liner play an integral role in the CSC performance. The performance of CSC liners has been relatively well-characterized for liners manufactured via hydroforming, hydraulic pressing, or turning on a CNC lathe. With advancements in Additive Manufacturing (AM) CSC liners can be 3D printed with metal powders. AM can provide significant design freedom in terms of realizing better properties through introduced hierarchic structuring or anisotropy. However, it is unclear as to how metal liners produced with Selective Laser Melting (SLM), will influence the conical shaped charge’s performance. This paper explores the performance, relative to the penetration of steel plates, of CSCs using 3D printed metal liners benchmarked against machined liners. The metal liners were printed with SLM parameters that were optimized to maximize the print density. The metal liner dimensions (thickness, height, and outer diameter) were designed using the recommended ratios of the liner’s inner diameter presented by Virgil (1988). The 3D printed metal liners are compared to a CNC machined liner, with the same dimensions. The comparison enables the evaluation of how 3D printing a liner influences penetration performance. The results indicate conical shaped charges could utilize 3D printed liners. These results open a wide range of performance design opportunities that cannot be achieved via conventional manufacturing and justify the current increased cost associated with additive manufacturing metal components. Future work will continue to explore how print density, printed material, and advanced geometries modify the conical shaped charge performance.
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Reports on the topic "CJC"

1

Carter, R. C. CFC and CHC reduction at suppliers. Final report. Office of Scientific and Technical Information (OSTI), July 1995. http://dx.doi.org/10.2172/83033.

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2

Lefkowitz, Larry, Jon Curtis, and Michael Witbrock. Accessible Research Cyc. Fort Belvoir, VA: Defense Technical Information Center, September 2007. http://dx.doi.org/10.21236/ada473356.

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Baldwin, R., and R. Rivest. The RC5, RC5-CBC, RC5-CBC-Pad, and RC5-CTS Algorithms. RFC Editor, October 1996. http://dx.doi.org/10.17487/rfc2040.

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Neal, Jeanette, Benjamin Rode, Chris Crowner, Dave Gunning, and John Gucwa. Leveraging Cyc for IAA. Fort Belvoir, VA: Defense Technical Information Center, January 2002. http://dx.doi.org/10.21236/ada401087.

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Reason, Joseph. Cooperative Engagement Capability (CEC). Fort Belvoir, VA: Defense Technical Information Center, November 2015. http://dx.doi.org/10.21236/ad1019001.

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Adams, Edward L., Everette D. Rast, and Neal D. Bennett. CNC router evaluation procedures. Radnor, PA: U.S. Department of Agriculture, Forest Service, Northeastern Forest Experiment Station, 1995. http://dx.doi.org/10.2737/ne-gtr-201.

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Neumeister, Michael W., Shaun D. Mendenhall, and Michael R. Ruebhausen. Thumb CMC Joint Arthroplasty. Touch Surgery Simulations, 2017. http://dx.doi.org/10.18556/touchsurgery/2017.s0116.

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Neumeister, Michael W. Thumb CMC Joint Arthroplasty. Touch Surgery Simulations, 2018. http://dx.doi.org/10.18556/touchsurgery/2018.s0116.

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Walsh, William E. Final CTC Archive Status Report: Operations and Maintenance Support for the CTC Archive. Fort Belvoir, VA: Defense Technical Information Center, September 1996. http://dx.doi.org/10.21236/ada314906.

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Yamada, R., J. Hawtree, K. Kaczar, R. Leverence, K. McGuire, C. Newman-Holmes, E. E. Schmidt, and J. Shallenberger. CDC field mapping device - ''ROTOTRACK''. Office of Scientific and Technical Information (OSTI), October 1985. http://dx.doi.org/10.2172/6459052.

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