Academic literature on the topic 'Chronic outcomes'

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Journal articles on the topic "Chronic outcomes"

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Kennedy, David W. "Outcomes in chronic rhinosinusitis." International Forum of Allergy & Rhinology 7, no. 12 (November 17, 2017): 1117–18. http://dx.doi.org/10.1002/alr.22050.

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Herald, G. Peter Praveen, and Suresh Kumar Cherlopalli. "FACTORS DETERMINING OUTCOMES IN ACUTE EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE." International Journal of Integrative Medical Sciences 5, no. 7 (August 20, 2018): 705–8. http://dx.doi.org/10.16965/ijims.2018.127.

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Mehta, Neel, Charles E. Inturrisi, Susan D. Horn, and Lisa R. Witkin. "Using Chronic Pain Outcomes Data to Improve Outcomes." Anesthesiology Clinics 34, no. 2 (June 2016): 395–408. http://dx.doi.org/10.1016/j.anclin.2016.01.009.

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Witkin, Lisa R., John T. Farrar, and Michael A. Ashburn. "Can Assessing Chronic Pain Outcomes Data Improve Outcomes?" Pain Medicine 14, no. 6 (April 9, 2013): 779–91. http://dx.doi.org/10.1111/pme.12075.

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Han, Wade W., and Richard E. Gliklich. "Outcomes research for chronic sinusitis." Current Opinion in Otolaryngology & Head and Neck Surgery 5, no. 1 (February 1997): 3–7. http://dx.doi.org/10.1097/00020840-199702000-00002.

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Bramham, K., B. Parnell, C. Nelson-Piercy, P. T. Seed, L. Poston, and L. C. Chappell. "Chronic Hypertension and Pregnancy Outcomes." Obstetric Anesthesia Digest 35, no. 1 (March 2015): 6–7. http://dx.doi.org/10.1097/01.aoa.0000460375.20198.f1.

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Benatar, Daniel, Mary Bondmass, Jaime Ghitelman, and Boaz Avitall. "Outcomes of Chronic Heart Failure." Archives of Internal Medicine 163, no. 3 (February 10, 2003): 347. http://dx.doi.org/10.1001/archinte.163.3.347.

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Lee, Paul P. "Measuring Outcomes in Chronic Diseases." Archives of Ophthalmology 121, no. 5 (May 1, 2003): 712. http://dx.doi.org/10.1001/archopht.121.5.712.

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Rahman, Hanif-ur, Sohail Amir, Mumtaz Ali, Shahid Ayub, Anisa Sundal, and Muhammad Ishaq. "Minimal Invasive Surgery for Chronic Subdural Hematoma." Pakistan Journal Of Neurological Surgery 25, no. 3 (September 30, 2021): 369–75. http://dx.doi.org/10.36552/pjns.v25i3.572.

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Objective: To assess significant improvement in terms of the Glasgow Coma Scale in patients subjected to minimally invasive surgery for a chronic subdural hematoma. Materials and Methods: A total of 80 patients with chronic subdural hematoma (CSDH) were enrolled in a sequential fashion using a retrospective study design. The patients were treated with minimally invasive surgery (MIS) and assessed at the end of the 2nd postoperative day (POD) for any significant improvement in the Glasgow coma scale (GCS). Results: There were 76.25% male and 23.75% female patients. A maximum number of patients (42.5%) were found with a GCS ranging from 9/15 – 11/15 (Class B) followed by Class A having GCS 12-13 (36.25%) and then Class C with GCS 5 – 8 (21.25% patients). In 86.2% and 13.7& of the patients, positive and negative outcomes were recorded. Maximum favorable surgical outcome was observed in 51-60 years of age group. In the majority of male patients, a favorable surgical outcome was reported. Similarly, a favorable surgical outcome was observed in Class B (GCS 9-11). There existed an insignificant difference between favorable surgical outcome vs. age groups, gender, and GCS class at baseline. Conclusion: This study found that CSDH using the MIS approach is linked to a high frequency of positive outcomes in terms of GCS improvement. A lower admission GCS score and older age are linked to a lower frequency of favorable outcomes and a higher likelihood of bad outcomes.
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Baumann, Ingo. "Subjective Outcomes Assessment in Chronic Rhinosinusitis." Open Otorhinolaryngology Journal 4, no. 1 (January 1, 2010): 28–33. http://dx.doi.org/10.2174/1874428101004010028.

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Dissertations / Theses on the topic "Chronic outcomes"

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Baker, Jannah F. "Bayesian spatiotemporal modelling of chronic disease outcomes." Thesis, Queensland University of Technology, 2017. https://eprints.qut.edu.au/104455/1/Jannah_Baker_Thesis.pdf.

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This thesis contributes to Bayesian spatial and spatiotemporal methodology by investigating techniques for spatial imputation and joint disease modelling, and identifies high-risk individual profiles and geographic areas for type II diabetes mellitus (DMII) outcomes. DMII and related chronic conditions including hypertension, coronary arterial disease, congestive heart failure and chronic obstructive pulmonary disease are examples of ambulatory care sensitive conditions for which hospitalisation for complications is potentially avoidable with quality primary care. Bayesian spatial and spatiotemporal studies are useful for identifying small areas that would benefit from additional services to detect and manage these conditions early, thus avoiding costly sequelae.
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Fenton, Grania. "Benchmarking outcomes for psychological treatments of chronic pain." Thesis, University of Leeds, 2010. http://etheses.whiterose.ac.uk/1087/.

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In an attempt to bridge the widely acknowledged gap between research and clinical practice, this thesis examined the feasibility of benchmarking outcomes for published psychological treatments of chronic pain for application within routine clinical settings. Benchmarking outcomes is relatively common for psychological treatments in the mental health field, but in spite of the prevalence of chronic pain and its known impact on many areas of functioning, the chronic pain literature has previously only considered the generic application of benchmarks for developing services and considering standards for waiting times. Four studies of mixed methodological approaches were conducted. The first aimed to ascertain the extent of similarities between published psychological treatments of chronic pain and treatments delivered in routine clinical settings. This was to ensure that the application of benchmarks from the published literature to routine clinical settings would be meaningful. The second study examined whether the published literature was likely to facilitate the development of benchmarks, and the third sought clarification in terms of outcome domains within which useful benchmarks could be generated. The final study was a meta-analysis of data extracted from the published literature within specified outcome domains. The results suggested that it would be meaningful to apply benchmarks produced from the published literature to routine clinical settings, and that the literature would facilitate the development of benchmarks within several outcome domains. The meta-analysis led to the generation of four benchmarks. These were in the outcome domains of pain experience and physical functioning when compared with waiting list controls, and coping and cognitive appraisal and emotional functioning when compared with active controls. The impact of the design of each study and properties inherent within the literature on the benchmarks generated and their application within routine clinical settings was then considered, prior to suggestions for future research and clinical applications.
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Painter, Jacob T. "CHRONIC OPIOID USE IN FIBROMYALGIA SYNDROME: CHARACTERISTICS AND OUTCOMES." UKnowledge, 2012. http://uknowledge.uky.edu/pharmacy_etds/5.

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Fibromyalgia syndrome (FMS) is a chronic pain condition with significant societal and personal burdens of illness. Chronic opioid therapy in the treatment of chronic nonmalignant pain has increased drastically over the past decade. This is a worrisome trend in general, but specifically, given the pathophysiologic characteristics seen in fibromyalgia syndrome patients, the use of this class of medication deserves special scrutiny. Although the theoretical case against this therapy choice is strong, little empirical evidence exists. In order to supplement this literature, retrospective analysis methods are utilized to examine the association of state-, provider-, and patient level characteristics with the prevalence of chronic opioid use in this disease state. Data gathered through this analysis is then used to develop a propensity index for the identification of an appropriate control group for fibromyalgia patients, a task that has proven difficult in the literature to date. Using propensity stratification and matching techniques analysis of the impact of fibromyalgia, chronic opioid use, and the interaction of these two variables are undertaken. Several key findings and updates to the understanding of chronic opioid use and fibromyalgia syndrome are reported. Wide geographic variation in chronic opioid utilization between states is seen. The role of diagnosing provider type in the rate of chronic opioid prescribing is significant and can be aggregated at various levels. Demographic characteristics, comorbid conditions, and concurrent medication use are all important associates of chronic opioid use in fibromyalgia syndrome. Additionally, chronic opioid use in fibromyalgia patients, independent of propensity to receive that therapy choice is a significant correlate with healthcare costs. A diagnosis of fibromyalgia is a statistically significant source of healthcare costs, though the clinical significance of its impact when compared to a closely matched control group is minimized. Despite the minimization of the role of this diagnosis the impact of the interaction of chronic opioid use with fibromyalgia, despite control for myriad regressors, is significant both statistically and clinically.
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Williams, Amanda Clare de Coetlogon. "Cognitive-behavioural management of chronic pain : models and outcomes." Thesis, King's College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406221.

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Fertuck, Deborah. "Children with chronic physical disorder : maternal characteristics and child outcomes." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=56618.

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The purpose of this study was to examine child psychosocial adjustment (i.e., behavioural problems and self-esteem) as a function of maternal well-being, parenting competence, and maternal stress in a sample of children (8 to 16 years) with a chronic physical disorder (CPD) (n = 60) as compared to a sample of non-chronically disabled children (n = 60). While the groups did not differ on either maternal variables or child behavioural problems, CPD children had higher self-esteem than comparison group children. For both groups, mothers with high well-being, high competence, and low stress had children with fewer behavioural problems. Furthermore, mothers of older CPD children perceived themselves as more competent parents, which in turn was related to fewer behavioural problems and higher self-esteem in the child. Mothers who assessed their child's condition as less stressful also had a higher sense of well-being and/or perceived themselves as more competent mothers. While this sample consisted of children whose conditions were of mild to moderate severity, children with more severe conditions had higher self-esteem.
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Methven, Shona. "Predictors of renal and patient outcomes in chronic kidney disease." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/3655/.

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Chronic kidney disease (CKD) is associated with an increased risk of cardiovascular disease and end stage renal failure. Accurate identification of those with a reduced glomerular filtration rate and significant proteinuria facilitates early diagnosis and risk stratification. This thesis explores the optimal measure of proteinuria, to accurately quantify proteinuria and as a predictor of renal and patient outcomes. We examine the prevalence of CKD in a general population cohort and assess the impact of different estimated glomerular filtration rate (eGFR) formulae. We explore the prognostic role of reduced eGFR and proteinuria in patients with hypertension and present the baseline characteristics of a community cohort study of patients with predominantly early CKD. They will be followed for ten years to identify predictors of cardiovascular and renal outcome. Urine total protein:creatinine ratio (TPCR) and albumin:creatinine ratio (ACR) have largely replaced 24-hour urine collections for proteinuria quantification. The performance of these spot measures to identify significant proteinuria is compared in a cohort of 6842 patients attending a general nephrology clinic. Both tests perform well overall but TPCR is statistically significantly superior as a predictor of 24-hour total proteinuria than ACR (as measured by the area under the receiver operator characteristic (ROC) curve to predict 1g/day total proteinuria). On sub-group analysis the performance of the spot samples is poorer in women and the elderly, likely as a result of low muscle mass and low urine creatinine (the denominator in TPCR/ACR). The performance of TPCR and ACR were then compared as predictors of outcome in a similar cohort of 5586 CKD patients using a hierarchical Cox survival model. TPCR and ACR both performed well as independent predictors of death, commencement of renal replacement therapy (RRT) and doubling of serum creatinine. Notably TPCR performed well at low levels where albuminuria has been considered superior. These findings are novel. The spot samples performed as well as 24-hour collections in the sub-group with timed urine collections. The National Institute for Health and Clinical Excellence in England recommend ACR to monitor all patients with CKD; the Scottish Intercollegiate Guidelines Network recommend TPCR for non-diabetic renal disease. Therefore, we investigated the implications of these recommendations using survival modelling. The same cohort was divided into 5 groups: no proteinuria, low proteinuria (using TPCR and ACR), high proteinuria (TPCR and ACR) and two groups where TPCR and ACR were discordant (i.e. TPCR above the diagnostic threshold but ACR below it and vice versa) using the recommended thresholds (ACR 30mg/mmol/TPCR 50mg/mmol to predict 0.5g/day total proteinuria and ACR 70mg/mmol/TPCR 100mg/mmol to predict 1g/day total proteinuria). Using univariate survival analysis the discordant group had significantly poorer outcomes (using the same outcomes as previously) than those with significant proteinuria as measured by both tests. The discordant group was older with poorer renal function and some of the excess risk was abolished on multivariate analysis, however the risk did not return to the level of those without detectable proteinuria. TPCR, but not ACR, measures non-albumin proteins and these may have pathophysiological roles in progression. This requires further study. However this analysis confirmed that TPCR identifies patients at high risk of adverse outcomes. TPCR and ACR may vary as a result of muscle mass. We adjusted TPCR and ACR for estimated creatinine excretion (ECE) (calculated using the Cockcroft and Gault formula) and performed cross-sectional and longitudinal analyses. Adjusting TPCR and ACR for ECE improves prediction of significant proteinuria in sub-groups with poor baseline test performance (such as women and the elderly) using ROC curve analysis. However when adjusted and unadjusted values were compared as predictors of outcome (using a net reclassification index analysis) adjusted values were significantly inferior. Urine creatinine is an independent predictor of mortality and hence may be directly contributing to the predictive value of TPCR and ACR rather than simply correcting for urine flow rate. As such, adjusting for ECE may act to remove the effect of a second independent predictor, leading to inferior test performance. Therefore the decision to adjust TPCR and ACR for ECE depends on the test application: to predict significant proteinuria adjustment of TPCR and ACR is of benefit, but adjustment leads to inferior performance as a prognostic test. The prevalence of CKD stages 3-5 was assessed using a general population laboratory database. Overall population prevalence was 5.63% using the modification of diet in renal disease (MDRD) formula and fell to 4.94% when the CKD-Epidemiology group (CKD-EPI) formulae were applied. Those reclassified to an earlier stage of CKD were predominantly middle aged women. Prevalence over a five year period was found to be stable using the CKD-EPI formulae but rose slightly according to MDRD. Proteinuria and eGFR were assessed as predictors of outcome in a large specialist hypertension clinic cohort. On multivariate survival analysis both baseline dipstick proteinuria and an eGFR<60ml/min/1.73m2 remained strong independent predictors of cardiovascular and all-cause mortality, despite intensive specialist intervention to control blood pressure. These simple tests should be advocated for risk stratification in these patients. Lastly the baseline characteristics of a community CKD cohort are presented. We recruited 411 participants from seven general practices around Ayrshire and a detailed baseline clinical and biochemical assessment was performed. Patients were invited to participate if they were included in the primary care register of CKD stages 3-5. Over a quarter had an eGFR>60ml/min/1.73m2 on the meat-fasted study sample. Proteinuria was of notably low prevalence and the cohort had a large burden of cardiovascular disease. Complications of renal disease were uncommon. The characteristics of the cohort differ from those under hospital follow-up. Their long term outcomes should contribute to refining risk stratification in this population. Proteinuria and eGFR are key aspects of diagnosis and monitoring in CKD. Identification of the optimal measures of both is essential and findings presented here contribute to that. There is a need to refine risk stratification in CKD, to identify those who require intensive intervention, and to reassure the rest. The findings of this thesis also contribute to that. Further study is required to refine the core aspects of diagnosis and investigation of CKD.
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Darvall, Katy Abigail Leigh. "Outcomes from ultrasound-guided foam sclerotherapy for chronic venous disease." Thesis, University of Birmingham, 2012. http://etheses.bham.ac.uk//id/eprint/3795/.

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The objective of this research is to investigate the role of ultrasound-guided foam sclerotherapy (UGFS) in the treatment of chronic venous disease (CVD). UGFS was found to be a safe and effective treatment for both primary and recurrent great saphenous vein (GSV) and small saphenous vein (SSV) incompetence, assessed by occlusion of treated veins on duplex ultrasound (DUS), and by disappearance of visible varicose veins (VV) on clinical examination. There was some evidence that healing of chronic venous ulcers (CVU) may be improved by UGFS when combined with compression bandaging. When compared with patients undergoing superficial venous surgery (SVS), UGFS was associated with significantly less pain, bruising and analgesia requirement, and a quicker return to work and driving. Significant improvements in both generic physical and disease-specific health-related quality of life (HRQL)were observed following UGFS, and were sustained for 12 months after treatment. UGFS significantly improved lower limb physical symptoms (pain, itching, restlessness, swelling, heaviness, cramp and tingling), cosmetic appearance, and provided life-style benefits in the majority of patients. Furthermore, the great majority of patients who expected such benefits had their expectations met or exceeded.
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Ramzam, Naveen, Hemang Panchal, Edward Leinaar, Christian Nwabueze, Shimin Zheng, and Timir Paul. "Investigating the Association between Chronic Kidney Diseasse and Clinical Outcomes." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/6300.

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Background: Chronic Kidney Disease (CKD) can be described as the loss of the kidney function over time. Symptoms usually develop slowly and it may not appear in early stages. Lab tests can confirm a CKD diagnosis. The approximate number of incidents per year is more than 200,000 cases and approximately 30 million people are living with CKD today in the United States. This long-standing disease ultimately leads to renal failure at the end. At this present time, there are no known cures for CKD and the only treatment available is dialysis. Objectives: The purpose of this study is to determine the association between CKD and further with Hemodialysis (HD) and medical condition such as cardiac complications, cardiogenic shock, hemorrhage, anemia, vascular complication, postop respiratory failure, post op infarct hemorrhage, acute renal failure, new temporary pacemaker, new permanent pacemaker, pericardial complications, and death. Methods: The study employed secondary data in a cross-sectional design. A sample of 106,969 was drawn from the population. The outcome variables were a diagnosis of CKD and/or CKD with HD. The predictor variables were cardiac complications, cardiogenic shock, hemorrhage, anemia, vascular complication, postop respiratory failure, post op infarct hemorrhage, acute renal failure, new temporary pacemaker, new permanent pacemaker, pericardial complications and death. Logistic regression was conducted to analyze the relationship between outcome variable and each independent variable. Variables with a p-value <0.05 were considered significant. Odds Ratio (OR) and 95% Confidence Intervals (CI) were reported and discussed. The statistical analysis was performed using SAS version 9.4. Results: Analysis shows that subjects with cardiac complications were 17% less likely to have CKD as compared to those who did not have cardiac complications (OR: 0.83, 95% CI: 0.78-0.88). CKD patients who had cardiac complications were 18% more likely to have HD than the subjects who did not have cardiac complications (OR: 1.18, 95% CI: 1.01-1.39). Patients with cardiogenic shock were 86% more likely to have CKD than the subjects who did not have cardiogenic shock (OR: 1.86, 95% CI: 1.82-1.91). CKD patients who had cardiogenic shock were also 18% more likely to have HD than the subjects who did not have cardiogenic shock (OR: 1.18, 95% CI: 1.11-1.25). Similar results have been reported if a patient had other conditions. Conclusion: Chronic kidney disease with hemodialysis is significantly associated by the other medical conditions such as cardiac complications cardiogenic shock, hemorrhage, anemia, vascular complication, postop respiratory failure, post op infarct hemorrhage, acute renal failure, new temporary pacemaker, new permanent pacemaker, pericardial complications and death in the United States. Further studies are needed to confirm the results and to understand the prognosis.
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Ramzan, Naveen, Shimin Zheng, Hemang Panchal, Edward Leinaar, Christian Nwabueze, and Timir K. Paul. "Investigating The Association Between Chronic Kidney Disease and Clinical Outcomes." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/21.

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Background Chronic Kidney Disease (CKD) can be described as the loss of the kidney function over time. Symptoms usually develop slowly, and it may not appear in early stages. Lab tests can confirm a CKD diagnosis. The approximate number of incidents per year is more than 200,000 cases, and approximately 30 million people are living with CKD today in the United States. This long-standing disease ultimately leads to renal failure at the end. At this present time, there are no known cures for CKD, and the only treatment available is dialysis. Objectives The purpose of this study is to determine the association between CKD and further with hemodialysis (HD) and medical condition such as cardiac complications, cardiogenic shock, hemorrhage, anemia, vascular complication, postop respiratory failure, post op infarct hemorrhage, acute renal failure, new temporary pacemaker, new permanent pacemaker, pericardial complications, and death. Study design The study employed secondary data in a cross-sectional design. Methods A sample of 106,969 was drawn from the population. The outcome variables were a diagnosis of CKD and/or CKD with HD. The predictor variables were cardiac complications, cardiogenic shock, hemorrhage, anemia, vascular complication, postop respiratory failure, post op infarct hemorrhage, acute renal failure, new temporary pacemaker, new permanent pacemaker, pericardial complications and death. Logistic regression was conducted to analyze the relationship between outcome variable and each independent variable. Variables with a p-value Results Analysis shows that subjects with cardiac complications were 17% less likely to have CKD as compared to those who did not have cardiac complications (OR: 0.83, 95% CI: 0.78-0.88). CKD patients who had cardiac complications were 18% more likely to have HD than the subjects who did not have cardiac complications (OR: 1.18, 95% CI: 1.01-1.39). Patients with cardiogenic shock were 86% more likely to have CKD than the subjects who did not have cardiogenic shock (OR: 1.86, 95% CI: 1.82-1.91). CKD patients who had cardiogenic shock were also 18% more likely to have HD than the subjects who did not have cardiogenic shock (OR: 1.18, 95% CI: 1.11-1.25). We have similar results if a patient had other conditions. Conclusion Chronic kidney disease with hemodialysis is significantly associated by the other medical conditions such as cardiac complications cardiogenic shock, hemorrhage, anemia, vascular complication, postop respiratory failure, post op infarct hemorrhage, acute renal failure, new temporary pacemaker, new permanent pacemaker, pericardial complications and death in the United States. Further studies are needed to confirm the results and to understand the prognosis.
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Shiu, Shiona. "Achieving equity in educational outcomes for students with chronic illness." View thesis, 2008. http://handle.uws.edu.au:8081/1959.7/19222.

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Thesis (Ed.D.)--University of Western Sydney, 2008.
A thesis submitted to the University of Western Sydney, College of Arts, School of Education, in fulfilment of the requirements for the degree of Doctor of Education. Includes bibliography.
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Books on the topic "Chronic outcomes"

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Stewart, Simon, and Lynda Blue, eds. Improving Outcomes in Chronic Heart Failure. London, UK: BMJ Publishing Group, 2004. http://dx.doi.org/10.1002/9780470750551.

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Kamudoni, Paul, Nutjaree Johns, and Sam Salek. Living with Chronic Disease: Measuring Important Patient-Reported Outcomes. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8414-0.

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Kurt, Banz, ed. Roferon-A in chronic viral hepatitis: Treatment, clinical outcomes, cost-effectiveness. Bern: P. Lang, 1994.

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Simon, Stewart, and Blue Lynda, eds. Improving outcomes in chronic heart failure: Specialist nurse intervention from research to practice. 2nd ed. London: BMJ Books, 2004.

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Husereau, Donald Robert. Interferon-based therapies for chronic hepatitis C virus infection: An assessment of clinical outcomes. Ottawa: Canadian Coordinating Office for Health Technology Assessment, 2004.

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Held, Philip J. Costs, competition, and outcomes in the End-Stage Renal Disease Program. Washington, D.C: Urban Institute, Health Policy Center, 1986.

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Rimington, Lesley D. A five year longitudinal outcome study of chronic obstructive pulmonary disease. Salford: University of Salford, 1994.

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Friedman, Stefan. Chronic Pain: Prevalence, Management and Outcomes. Nova Science Publishers, Incorporated, 2019.

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Beaulieu, Monica, Catherine Weber, Nadia Zalunardo, and Adeera Levin. Chronic kidney disease long-term outcomes. Edited by David J. Goldsmith. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0097.

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Chronic kidney disease (CKD) is associated with a variety of outcomes, some of which are directly and indirectly related to kidney disease, but which ultimately impact on patients’ quality of life and long-term outcomes. The events to which people with CKD are exposed ultimately determine their risk and prognosis of both progression to needing renal replacement therapy, or other morbidities and mortalities. The notion of competing risk is important. The five major outcomes of CKD are: progression of CKD, progression to ESRD (either dialysis or transplantation); death; cardiovascular events; infections; and hospitalizations. Where data is available, not only the risk of the specific outcome, but the factors which may predict those outcomes are described. Each section describes what is currently known about the frequency of the outcome, the limitations of that knowledge, the risk factors associated with outcome, and implications for care and future research. Available published literature often describes outcomes in CKD populations as if it is a homogenous group of patients. But it is well documented that outcomes in those with CKD differ depending on stage or severity, and whether they are or are not known to specialists. Where possible, each section ensures that the specific CKD cohort(s) from which the information is derived is clearly described.
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Page, Clive P., Mario Cazzola, and Fernando J. Martinez. Chronic Obstructive Pulmonary Disease: Outcomes and Biomarkers. Taylor & Francis Group, 2009.

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Book chapters on the topic "Chronic outcomes"

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Powell, Lynda H., Peter G. Kaufmann, and Kenneth E. Freedland. "Outcomes." In Behavioral Clinical Trials for Chronic Diseases, 209–36. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-39330-4_9.

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Kent, Michael. "Patient Reported Outcomes." In Hospitalized Chronic Pain Patient, 37–43. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-08376-1_9.

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Láinez, Miguel J. A., and Ane Mínguez-Olaondo. "Pharmacologic Approaches to CDH: Evidence and Outcomes." In Chronic Headache, 217–30. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-91491-6_16.

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Slater, Shalonda S., and Hope L. O’Brien. "Behavioral Approaches to CDH: Evidence and Outcomes." In Chronic Headache, 231–38. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-91491-6_17.

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Wang, Margaret C., and Jim Bellows. "Quality of Life and Patient-Centered Outcomes." In Chronic Illness Care, 95–107. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-71812-5_8.

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Israel, Jacqueline S., Lisa Gfrerer, William Gerald Austen, and Ahmed M. Afifi. "Outcomes in Migraine Surgery." In Surgical Treatment of Chronic Headaches and Migraines, 183–93. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-36794-7_15.

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Vasquez, Michael, and Linda Harris. "Outcomes assessment for chronic venous disease." In Handbook of Venous and Lymphatic Disorders, 771–81. Taylor & Francis Group, 6000 Broken Sound Parkway NW, Suite 300, Boca Raton, FL 33487-2742: CRC Press, 2016. http://dx.doi.org/10.1201/9781315382449-75.

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Lee, Jae Jin, and Martine Extermann. "Impact of Comorbidity on Treatment Decision Making and Outcomes." In Cancer and Chronic Conditions, 131–58. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-1844-2_5.

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Field, Clint, and Rachel Duchoslav. "Family Influence on Adolescent Treatment Outcomes." In Behavioral Approaches to Chronic Disease in Adolescence, 47–54. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-87687-0_5.

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Wagner, Julie, and Howard Tennen. "Coping with Diabetes: Psychological Determinants of Diabetes Outcomes." In Coping with Chronic Illness and Disability, 215–39. Boston, MA: Springer US, 2007. http://dx.doi.org/10.1007/978-0-387-48670-3_11.

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Conference papers on the topic "Chronic outcomes"

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Wise, Robert A., Antonio Anzueto, Achim Mueller, Norbert Metzdorf, and Peter M. A. Calverley. "Tiotropium in chronic obstructive pulmonary disease: Gender differences in outcomes." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa298.

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Tita, Alan, and Rachel Giles. "Treating chronic mild hypertension during pregnancy leads to better outcomes." In 71st ACC Scientific Session, edited by Marc Bonaca. Baarn, the Netherlands: Medicom Medical Publishers, 2022. http://dx.doi.org/10.55788/f538e95e.

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Kanaya, A., C. W. Emala, and M. Mikami. "Chronic Allergic Lung Inflammation Negatively Influences Neurobehavioral Outcomes in Mice." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3759.

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Agarwal, Kshitij, Anuradha Chowdhary, M. Rahman, Anil Chaudhry, and S. N. Gaur. "Risk factors and treatment outcomes in patients with chronic pulmonary aspergillosis." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa2647.

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Nieri, Dario, Elisa Ageno, Laura Malagrinò, Francesco Costa, Sabrina Santerini, Sandra Antonelli, Claudia De Simone, Giovanna De Cusatis, Barbara Vagaggini, and Pierluigi Paggiaro. "Outcomes of a pulmonary rehabilitation program in chronic obstructive pulmonary disease." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa3580.

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Balasubramanian, A., R. Henderson, N. Putcha, A. Fawzy, S. Raju, N. N. Hansel, N. R. MacIntyre, et al. "Hemoglobin as a Biomarker for Clinical Outcomes in Chronic Obstructive Pulmonary Disease." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4000.

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O'Toole, J., N. Putcha, C. B. Cooper, P. Woodruff, R. E. Kanner, R. Paine, R. P. Bowler, et al. "Contribution of Anxiety and Depression on Chronic Obstructive Pulmonary Disease (COPD) Outcomes." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5567.

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Mcgarvey, Lorcan, Alyn Morice, Nate Way, Vicky Li, Jessica Weaver, Ishita Doshi, Eduardo Urdaneta, and Robert Boggs. "Prevalence of chronic cough, patient characteristics and health outcomes among UK adults." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa3327.

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Wereski, Ryan, PD Adamson, NS Shek Daud, Fiona Strachan, Caelan Taggart, Anda Bularga, Dorien Kimenai, et al. "167 Predicting outcomes in chronic coronary syndromes with high-sensitivity cardiac troponin." In British Cardiovascular Society Annual Conference, ‘100 years of Cardiology’, 6–8 June 2022. BMJ Publishing Group Ltd and British Cardiovascular Society, 2022. http://dx.doi.org/10.1136/heartjnl-2022-bcs.167.

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Kyriakopoulos, G., F. Occhigrossi, F. Cassini, L. Chen, and R. Jain. "B362 Real-world outcomes using thermal radiofrequency (TRF) ablation for chronic pain." In ESRA Abstracts, 39th Annual ESRA Congress, 22–25 June 2022. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/rapm-2022-esra.438.

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Reports on the topic "Chronic outcomes"

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Damiano, Peter, Suzanne Bentler, Jason Wachsmuth, Elizabeth Momany, Phuong Nguyen-Hoang, and Dan M. Shane. Outcomes for Iowa Medicaid Chronic Condition Health Home Program Enrollees SFYs 2012-2015. Iowa City, Iowa: University of Iowa Public Policy Center, February 2017. http://dx.doi.org/10.17077/73yf-djhe.

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Treadwell, Jonathan R., James T. Reston, Benjamin Rouse, Joann Fontanarosa, Neha Patel, and Nikhil K. Mull. Automated-Entry Patient-Generated Health Data for Chronic Conditions: The Evidence on Health Outcomes. Agency for Healthcare Research and Quality (AHRQ), March 2021. http://dx.doi.org/10.23970/ahrqepctb38.

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Background. Automated-entry consumer devices that collect and transmit patient-generated health data (PGHD) are being evaluated as potential tools to aid in the management of chronic diseases. The need exists to evaluate the evidence regarding consumer PGHD technologies, particularly for devices that have not gone through Food and Drug Administration evaluation. Purpose. To summarize the research related to automated-entry consumer health technologies that provide PGHD for the prevention or management of 11 chronic diseases. Methods. The project scope was determined through discussions with Key Informants. We searched MEDLINE and EMBASE (via EMBASE.com), In-Process MEDLINE and PubMed unique content (via PubMed.gov), and the Cochrane Database of Systematic Reviews for systematic reviews or controlled trials. We also searched ClinicalTrials.gov for ongoing studies. We assessed risk of bias and extracted data on health outcomes, surrogate outcomes, usability, sustainability, cost-effectiveness outcomes (quantifying the tradeoffs between health effects and cost), process outcomes, and other characteristics related to PGHD technologies. For isolated effects on health outcomes, we classified the results in one of four categories: (1) likely no effect, (2) unclear, (3) possible positive effect, or (4) likely positive effect. When we categorized the data as “unclear” based solely on health outcomes, we then examined and classified surrogate outcomes for that particular clinical condition. Findings. We identified 114 unique studies that met inclusion criteria. The largest number of studies addressed patients with hypertension (51 studies) and obesity (43 studies). Eighty-four trials used a single PGHD device, 23 used 2 PGHD devices, and the other 7 used 3 or more PGHD devices. Pedometers, blood pressure (BP) monitors, and scales were commonly used in the same studies. Overall, we found a “possible positive effect” of PGHD interventions on health outcomes for coronary artery disease, heart failure, and asthma. For obesity, we rated the health outcomes as unclear, and the surrogate outcomes (body mass index/weight) as likely no effect. For hypertension, we rated the health outcomes as unclear, and the surrogate outcomes (systolic BP/diastolic BP) as possible positive effect. For cardiac arrhythmias or conduction abnormalities we rated the health outcomes as unclear and the surrogate outcome (time to arrhythmia detection) as likely positive effect. The findings were “unclear” regarding PGHD interventions for diabetes prevention, sleep apnea, stroke, Parkinson’s disease, and chronic obstructive pulmonary disease. Most studies did not report harms related to PGHD interventions; the relatively few harms reported were minor and transient, with event rates usually comparable to harms in the control groups. Few studies reported cost-effectiveness analyses, and only for PGHD interventions for hypertension, coronary artery disease, and chronic obstructive pulmonary disease; the findings were variable across different chronic conditions and devices. Patient adherence to PGHD interventions was highly variable across studies, but patient acceptance/satisfaction and usability was generally fair to good. However, device engineers independently evaluated consumer wearable and handheld BP monitors and considered the user experience to be poor, while their assessment of smartphone-based electrocardiogram monitors found the user experience to be good. Student volunteers involved in device usability testing of the Weight Watchers Online app found it well-designed and relatively easy to use. Implications. Multiple randomized controlled trials (RCTs) have evaluated some PGHD technologies (e.g., pedometers, scales, BP monitors), particularly for obesity and hypertension, but health outcomes were generally underreported. We found evidence suggesting a possible positive effect of PGHD interventions on health outcomes for four chronic conditions. Lack of reporting of health outcomes and insufficient statistical power to assess these outcomes were the main reasons for “unclear” ratings. The majority of studies on PGHD technologies still focus on non-health-related outcomes. Future RCTs should focus on measurement of health outcomes. Furthermore, future RCTs should be designed to isolate the effect of the PGHD intervention from other components in a multicomponent intervention.
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Newberry, Sydne J., Mei Chung, Cheryl A. M. Anderson, Christine Chen, Zhuxuan Fu, Alice Tang, Naisi Zhao, et al. Effects of Dietary Sodium and Potassium Intake on Chronic Disease Outcomes and Related Risk Factors. Agency for Healthcare Research and Quality (AHRQ), March 2018. http://dx.doi.org/10.23970/ahrqepccer206.

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Ciapponi, Agustín. Do decision support and clinical information systems improve the healthcare process and health outcomes for people living with HIV? SUPPORT, 2016. http://dx.doi.org/10.30846/161013.

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The overall number of people living with HIV has steadily increased, as HIV treatments extend life. As HIV infection is shifting mostly to a chronic disease managed primarily in the ambulatory setting, chronic disease management interventions such as decision support and clinical information systems might be useful to this population.
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Allen, Heidi, and Katherine Baicker. The Effect of Medicaid on Care and Outcomes for Chronic Conditions: Evidence from the Oregon Health Insurance Experiment. Cambridge, MA: National Bureau of Economic Research, October 2021. http://dx.doi.org/10.3386/w29373.

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Wu, Lihua, Hongmei Lu, Ling Wu, Bo Qu, Yu Liu, and Mingquan Li. Effects of exercise on inflammation and nutrition outcomes in patients with chronic kidney disease: a protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2020. http://dx.doi.org/10.37766/inplasy2020.10.0025.

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Zhu, Huafeng, Haixing Fang, Qunfeng Xia, Jianfeng Cai, and Tianwei Fu. Finerenone reduces risk of cardiovascular outcomes in patients with chronic kidney disease and type 2 diabetes: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2022. http://dx.doi.org/10.37766/inplasy2022.3.0052.

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Dy, Sydney M., Julie M. Waldfogel, Danetta H. Sloan, Valerie Cotter, Susan Hannum, JaAlah-Ai Heughan, Linda Chyr, et al. Integrating Palliative Care in Ambulatory Care of Noncancer Serious Chronic Illness: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), February 2020. http://dx.doi.org/10.23970/ahrqepccer237.

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Objectives. To evaluate availability, effectiveness, and implementation of interventions for integrating palliative care into ambulatory care for U.S.-based adults with serious life-threatening chronic illness or conditions other than cancer and their caregivers We evaluated interventions addressing identification of patients, patient and caregiver education, shared decision-making tools, clinician education, and models of care. Data sources. We searched key U.S. national websites (March 2020) and PubMed®, CINAHL®, and the Cochrane Central Register of Controlled Trials (through May 2020). We also engaged Key Informants. Review methods. We completed a mixed-methods review; we sought, synthesized, and integrated Web resources; quantitative, qualitative and mixed-methods studies; and input from patient/caregiver and clinician/stakeholder Key Informants. Two reviewers screened websites and search results, abstracted data, assessed risk of bias or study quality, and graded strength of evidence (SOE) for key outcomes: health-related quality of life, patient overall symptom burden, patient depressive symptom scores, patient and caregiver satisfaction, and advance directive documentation. We performed meta-analyses when appropriate. Results. We included 46 Web resources, 20 quantitative effectiveness studies, and 16 qualitative implementation studies across primary care and specialty populations. Various prediction models, tools, and triggers to identify patients are available, but none were evaluated for effectiveness or implementation. Numerous patient and caregiver education tools are available, but none were evaluated for effectiveness or implementation. All of the shared decision-making tools addressed advance care planning; these tools may increase patient satisfaction and advance directive documentation compared with usual care (SOE: low). Patients and caregivers prefer advance care planning discussions grounded in patient and caregiver experiences with individualized timing. Although numerous education and training resources for nonpalliative care clinicians are available, we were unable to draw conclusions about implementation, and none have been evaluated for effectiveness. The models evaluated for integrating palliative care were not more effective than usual care for improving health-related quality of life or patient depressive symptom scores (SOE: moderate) and may have little to no effect on increasing patient satisfaction or decreasing overall symptom burden (SOE: low), but models for integrating palliative care were effective for increasing advance directive documentation (SOE: moderate). Multimodal interventions may have little to no effect on increasing advance directive documentation (SOE: low) and other graded outcomes were not assessed. For utilization, models for integrating palliative care were not found to be more effective than usual care for decreasing hospitalizations; we were unable to draw conclusions about most other aspects of utilization or cost and resource use. We were unable to draw conclusions about caregiver satisfaction or specific characteristics of models for integrating palliative care. Patient preferences for appropriate timing of palliative care varied; costs, additional visits, and travel were seen as barriers to implementation. Conclusions. For integrating palliative care into ambulatory care for serious illness and conditions other than cancer, advance care planning shared decision-making tools and palliative care models were the most widely evaluated interventions and may be effective for improving only a few outcomes. More research is needed, particularly on identification of patients for these interventions; education for patients, caregivers, and clinicians; shared decision-making tools beyond advance care planning and advance directive completion; and specific components, characteristics, and implementation factors in models for integrating palliative care into ambulatory care.
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Chou, Roger, Rongwei Fu, Tracy Dana, Miranda Pappas, Erica Hart, and Kimberly M. Mauer. Interventional Treatments for Acute and Chronic Pain: Systematic Review. Agency for Healthcare Research and Quality (AHRQ), September 2021. http://dx.doi.org/10.23970/ahrqepccer247.

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Objective. To evaluate the benefits and harms of selected interventional procedures for acute and chronic pain that are not currently covered by the Centers for Medicare & Medicaid Services (CMS) but are relevant for and have potential utility for use in the Medicare population, or that are covered by CMS but for which there is important uncertainty or controversy regarding use. Data sources. Electronic databases (Ovid® MEDLINE®, PsycINFO®, the Cochrane Central Register of Controlled Trials, and the Cochrane Database of Systematic Reviews) to April 12, 2021, reference lists, and submissions in response to a Federal Register notice. Review methods. Using predefined criteria and dual review, we selected randomized controlled trials (RCTs) for 10 interventional procedures and conditions that evaluated pain, function, health status, quality of life, medication use, and harms. Random effects meta-analysis was conducted for vertebral compression fracture; otherwise, outcomes were synthesized qualitatively. Effects were classified as small, moderate, or large using previously defined criteria. Results. Thirty-seven randomized trials (in 48 publications) were included. Vertebroplasty (13 trials) is probably more effective at reducing pain and improving function in older (>65 years of age) patients, but benefits are small (less than 1 point on a 10-point pain scale). Benefits appear smaller (but still present) in sham-controlled (5 trials) compared with usual care controlled trials (8 trials) and larger in trials of patients with more acute symptoms; however, testing for subgroup effects was limited by imprecision. Vertebroplasty is probably not associated with increased risk of incident vertebral fracture (10 trials). Kyphoplasty (2 trials) is probably more effective than usual care for pain and function in older patients with vertebral compression fracture at up to 1 month (moderate to large benefits) and may be more effective at >1 month to ≥1 year (small to moderate benefits) but has not been compared against sham therapy. Evidence on kyphoplasty and risk of incident fracture was conflicting. In younger (below age for Medicare eligibility) populations, cooled radiofrequency denervation for sacroiliac pain (2 trials) is probably more effective for pain and function versus sham at 1 and 3 months (moderate to large benefits). Cooled radiofrequency for presumed facet joint pain may be similarly effective versus conventional radiofrequency, and piriformis injection with corticosteroid for piriformis syndrome may be more effective than sham injection for pain. For the other interventional procedures and conditions addressed, evidence was too limited to determine benefits and harms. Conclusions. Vertebroplasty is probably effective at reducing pain and improving function in older patients with vertebral compression fractures; benefits are small but similar to other therapies recommended for pain. Evidence was too limited to separate effects of control type and symptom acuity on effectiveness of vertebroplasty. Kyphoplasty has not been compared against sham but is probably more effective than usual care for vertebral compression fractures in older patients. In younger populations, cooled radiofrequency denervation is probably more effective than sham for sacroiliac pain. Research is needed to determine the benefits and harms of the other interventional procedures and conditions addressed in this review.
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Czerwaty, Katarzyna, Karolina Dżaman, Krystyna Maria Sobczyk, and Katarzyna Irmina Sikrorska. The Overlap Syndrome of Obstructive Sleep Apnea and Chronic Obstructive Pulmonary Disease: A Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0077.

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Review question / Objective: To provide the essential findings in the field of overlap syndrome of chronic obstructive pulmonary disease and obstructive sleep apnea, including prevalence, possible predictors, association with clinical outcomes, and severity compared to both chronic obstructive pulmonary disease and obstructive sleep apnea patients. Condition being studied: OSA is characterized by complete cessation (apnea) or significant decrease (hy-popnea) in airflow during sleep and recurrent episodes of upper airway collapse cause it during sleep leading to nocturnal oxyhemoglobin desaturations and arousals from rest. The recurrent arousals which occur in OSA lead to neurocognitive consequences, daytime sleepiness, and reduced quality of life. Because of apneas and hypopneas, patients are experiencing hypoxemia and hypercapnia, which result in increasing levels of catecholamine, oxidative stress, and low-grade inflammation that lead to the appearance of cardio-metabolic consequences of OSA. COPD is a chronic inflammatory lung disease defined by persistent, usually pro-gressive AFL (airflow limitation). Changes in lung mechanics lead to the main clini-cal manifestations of dyspnea, cough, and chronic expectoration. Furthermore, patients with COPD often suffer from anxiety and depression also, the risk of OSA and insomnia is higher than those hospitalized for other reasons. Although COPD is twice as rare as asthma but is the cause of death eight times more often.
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