Dissertations / Theses on the topic 'Chronic Obstructive Pulmonary Disease'
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McAllister, David Anthony. "Chronic obstructive pulmonary disease, pulmonary function and cardiovascular disease." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5615.
Full textMurphy, Nicola. "Chronic obstructive pulmonary disease and anxiety." Thesis, Coventry University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368862.
Full textRoos-Engstrand, Ester. "T cells in chronic obstructive pulmonary disease." Doctoral thesis, Umeå : Umeå university, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-33677.
Full textStevenson, Nicola Jane. "Lung mechanics in chronic obstructive pulmonary disease." Thesis, University of Liverpool, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432977.
Full textAl-shair, Khaled. "Systemic Manifestations of Chronic Obstructive Pulmonary Disease." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509061.
Full textRevill, Susan M. "Endurance exercise in chronic obstructive pulmonary disease." Thesis, Loughborough University, 1997. https://dspace.lboro.ac.uk/2134/15388.
Full textPolkey, Michael Iain. "Diaphragm function in chronic obstructive pulmonary disease." Thesis, King's College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286262.
Full textDonaldson, Anna. "Circulating microRNA in Chronic Obstructive Pulmonary Disease." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/24776.
Full textTaylor, Abigail Elizabeth. "Macrophage phagocytosis in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2009. http://hdl.handle.net/10044/1/7374.
Full textBaldrick, Francina Rose. "Diet and chronic obstructive pulmonary disease (COPD)." Thesis, Queen's University Belfast, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527657.
Full textNoell, Guillaume. "Multi-Level Integrated Analysis of Chronic Obstructive Pulmonary Disease (COPD) heterogeneity." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/667980.
Full textSolomon, Brahm Kevin. "Psychological Aspects of Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34292.
Full textGreening, Neil James. "Early pulmonary rehabilitation for exacerbations of chronic obstructive pulmonary disease." Thesis, University of Leicester, 2014. http://hdl.handle.net/2381/29155.
Full textJohn, Michelle. "The extra-pulmonary effects of chronic obstructive pulmonary disease (COPD)." Thesis, University of Nottingham, 2014. http://eprints.nottingham.ac.uk/14405/.
Full textMarante, Tânia Alves. "The impact of chronic obstructive pulmonary disease on iNKT lymphocytes." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/17144.
Full textA doença pulmonar obstrutiva crónica (DPOC) é uma das doenças inflamatórias mais comuns das vias aéreas e uma das principais causas de morbidade e mortalidade em todo o mundo. A doença é caracterizada por uma limitação persistente do fluxo aéreo, geralmente progressiva. As respostas inflamatórias crónicas e imunes desempenham papéis fundamentais no desenvolvimento e progressão da DPOC. A inflamação é uma resposta protetora normal, mas na DPOC esta inflamação é amplificada. Várias células inflamatórias, seus mediadores e enzimas participam na resposta inflamatória na DPOC. A reabilitação respiratória é um componente fundamental da gestão da doença pulmonar obstrutiva crónica. Ela é projetada para melhorar a condição física e psicológica de pessoas com doenças respiratórias crónicas e para promover a adesão a longo prazo do comportamento que melhora a saúde. O objetivo principal deste trabalho foi contribuir para a compreensão do papel das células iNKT na patologia da DPOC. Além disso, também pretendemos explorar o efeito da reabilitação respiratória nas células iNKT em pacientes com DPOC. Análises clínicas e imunológicas foram feitas em pacientes com DPOC (n=7), pacientes com DPOC que realizaram reabilitação respiratória (n=4) e controlos saudáveis com idade e género idêntico aos doentes (n=14). Os participantes foram estudados duas vezes, com um intervalo de 12 semanas. Foram estudados os seguintes parâmetros clínicos: índice de massa corporal, percentagem de massa gorda, função pulmonar, força dos músculos respiratórios, força muscular isométrica, teste das cinco repetições sentar-levantar, teste de avaliação da DPOC e questionário da dispneia. As células iNKT foram estudadas em termos de percentagem, fenótipo, citotoxicidade e produção de citocinas. Não foi observada nenhuma alteração na percentagem de células iNKT, seus subconjuntos e produção de citocinas no sangue periférico de pacientes com DPOC em comparação com os controlos. Os nossos resultados sugeriram que as células iNKT de pacientes com DPOC podem ter uma diminuição na ativação precoce pela redução da expressão do CD69. Foi também sugerida uma redução na capacidade citotóxica em doentes. A reabilitação respiratória não pareceu afetar a redução da expressão do CD69, mas pareceu contribuir para o aumento da citotoxicidade das células iNKT e desempenhar um papel na melhoria do defeito citotóxico. Este é o primeiro estudo que conduziu uma extensa análise de correlações entre variáveis clínicas para a DPOC e variáveis imunológicas. Os resultados das nossas correlações indicaram que algumas células podem estar associadas a uma melhoria no estado de saúde do paciente e outras com o agravamento da DPOC. Este foi um estudo exploratório, e mais investigações sobre este tema são necessárias para fortalecer as conclusões.
Chronic obstructive pulmonary disease (COPD) is one of the most common inflammatory diseases of the airways and a leading cause of morbidity and mortality worldwide. The disease is characterized by a persistent airflow limitation, generally progressive. Chronic inflammatory and immune responses play key roles in the development and progression of COPD. The inflammation is a normal protective response, but in COPD this inflammation is amplified. Several inflammatory cells, their mediators and enzymes participate in the inflammatory response in COPD. Pulmonary rehabilitation is a core component of chronic obstructive pulmonary disease management. It is designed to improve the physical and psychological condition of people with chronic respiratory disease and to promote the long-term adherence of health-enhancing behavior. The main aim of this work was to contribute for understanding the role of iNKT cells in COPD pathology. In addition we also aimed to explore the effect of pulmonary rehabilitation on the iNKT cells in patients with COPD. Clinical and immunological analysis were done in patients with COPD (n=7), patients with COPD performing pulmonary rehabilitation (n=4) and age- and gender-matched healthy controls (n=14). Participants were studied twice, with an interval of 12 weeks. The following clinical parameters were studied: body mass index, body fat percentage, pulmonary function, respiratory muscle strength, quadriceps muscle strength, five time seat to stand, COPD assessment test and modified medical research council. The iNKT cells were studied in terms of percentage, phenotype, cytotoxicity and cytokine production. No alteration in percentage of iNKT cells, their subsets and cytokine production were observed in the peripheral blood of patients with COPD in comparison with controls. Our results suggested that iNKT cells from patients with COPD might have a decrease in early activation by reduction of CD69 expression. A reduction in cytotoxic capacity in patients was also suggested. Pulmonary rehabilitation did not seem to affect the reduction of CD69 expression, but seemed to contribute to the increase in iNKT cell cytotoxicity and might have a role in improving the cytotoxic defect. This is the first study that conducted an extensive correlation analysis between clinical variables for COPD and immunological variables. Findings from our correlations indicated that some cells might be associated with an improvement in the health condition of the patient, and others with the worsening of COPD. This was an exploratory study, and further research on this topic is warranted to strengthen conclusions.
Puhan, Milo Alan. "Patient-oriented research in chronic obstructive pulmonary disease /." Zürich, 2005. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000253399.
Full textRoberts, Della Kim. "The family experience with chronic obstructive pulmonary disease." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/24422.
Full textApplied Science, Faculty of
Nursing, School of
Graduate
Thomas, Catherine. "Defective innate immunity in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/40171.
Full textCamp, Patricia. "Sex and gender in chronic obstructive pulmonary disease." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/1410.
Full textSze, Marc Alexander. "The lung microbiome in chronic obstructive pulmonary disease." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/36343.
Full textHopkinson, Nicholas Shaun. "Skeletal muscle dysfunction in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417140.
Full textUrbanowicz, Richard Antoni. "Peripheral cytotoxic cells in chronic obstructive pulmonary disease." Thesis, University of Nottingham, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490982.
Full textSwallow, Elisabeth. "Skeletal muscle dysfunction in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508993.
Full textEltboli, Osama M. I. "Eosinophilic airways inflammation in Chronic Obstructive Pulmonary Disease." Thesis, University of Leicester, 2015. http://hdl.handle.net/2381/32546.
Full textHobbs, Brian. "Exome Array Analysis of Chronic Obstructive Pulmonary Disease." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:22837731.
Full textAlhaddad, Maath. "Cardiopulmonary manifestations in chronic obstructive pulmonary disease (COPD)." Thesis, University of Nottingham, 2015. http://eprints.nottingham.ac.uk/30008/.
Full textSantiago, Pia Bantegui. "Adherence to exercise following pulmonary rehabilitation of chronic obstructive pulmonary disease /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2004. http://wwwlib.umi.com/cr/ucsd/fullcit?p3130214.
Full textBatlle, Garcia Jordi de 1981. "Measure and effect of diet in chronic obstructive pulmonary disease." Doctoral thesis, Universitat Pompeu Fabra, 2011. http://hdl.handle.net/10803/52896.
Full textAntecedents i objectius: Estudis recents mostren associacions entre una dieta sana i reduccions en la incidència de malaltia pulmonar obstructiva crònica (MPOC). Tanmateix, el possible rol de la dieta en l'evolució de l'MPOC és desconegut. L'objectiu d'aquesta tesi és descriure les característiques de la dieta en pacients amb MPOC i estimar-ne l’associació amb l'evolució de la malaltia en termes d’alteracions fisiopatològiques i hospitalitzacions. Com a objectiu secundari, també es vol estudiar el paper de la dieta en l'asma, com a malaltia estretament relacionada amb l'MPOC. Mètodes: Es va aniuar un protocol d’epidemiologia nutricional en una cohort de 342 malalts d’MPOC, ben fenotipats, reclutats a Espanya durant la seva primera hospitalització per agudització de l'MPOC. Es va administrar un qüestionari de freqüència de consum d'aliments (122 ítems) preguntant per la dieta dels darrers 2 anys. Es van mesurar en sèrum els nivells de marcadors d'estrès oxidatiu i d'inflamació. Les hospitalitzacions durant el temps de seguiment s’obtingueren a partir de registres nacionals. Per últim, s'utilitzaren dades de l'International Study of Asthma and Allergy in Childhood (ISAAC) a Mèxic per a estimar l'efecte de la dieta en l'asma infantil. Resultats: (i) El consum d'aliments i macro- i micro-nutrients fou considerat adient respecte a les recomanacions locals, exceptuant la vitamina D; (ii) la ingesta de vitamina E i oli d’oliva s’associà a menors nivells d’estrès oxidatiu en pacients fumadors actius; (iii) els nivells de ingesta d'àcids grassos _3 i _6 es va relacionar amb els nivells d’inflamació sistèmica; (iv) la ingesta d’embotits i carns curades va incrementar el risc d'hospitalització per MPOC durant el seguiment; i (v) l’adherència a un patró mediterrani d'alimentació s’associà a menor prevalença d'asma infantil. Conclusions: Els hàbits alimentaris poden modificar l'evolució de l'MPOC i el desenvolupament d'asma infantil. Per tant, s’hauria de considerar l’inclusió de consells alimentaris en les guies clíniques per a malalties respiratòries cròniques.
Batlle, Garcia Jordi de. "Measure and effect of diet in chronic obstructive pulmonary disease." Doctoral thesis, Universitat Pompeu Fabra, 2011. http://hdl.handle.net/10803/52896.
Full textAntecedents i objectius: Estudis recents mostren associacions entre una dieta sana i reduccions en la incidència de malaltia pulmonar obstructiva crònica (MPOC). Tanmateix, el possible rol de la dieta en l'evolució de l'MPOC és desconegut. L'objectiu d'aquesta tesi és descriure les característiques de la dieta en pacients amb MPOC i estimar-ne l’associació amb l'evolució de la malaltia en termes d’alteracions fisiopatològiques i hospitalitzacions. Com a objectiu secundari, també es vol estudiar el paper de la dieta en l'asma, com a malaltia estretament relacionada amb l'MPOC. Mètodes: Es va aniuar un protocol d’epidemiologia nutricional en una cohort de 342 malalts d’MPOC, ben fenotipats, reclutats a Espanya durant la seva primera hospitalització per agudització de l'MPOC. Es va administrar un qüestionari de freqüència de consum d'aliments (122 ítems) preguntant per la dieta dels darrers 2 anys. Es van mesurar en sèrum els nivells de marcadors d'estrès oxidatiu i d'inflamació. Les hospitalitzacions durant el temps de seguiment s’obtingueren a partir de registres nacionals. Per últim, s'utilitzaren dades de l'International Study of Asthma and Allergy in Childhood (ISAAC) a Mèxic per a estimar l'efecte de la dieta en l'asma infantil. Resultats: (i) El consum d'aliments i macro- i micro-nutrients fou considerat adient respecte a les recomanacions locals, exceptuant la vitamina D; (ii) la ingesta de vitamina E i oli d’oliva s’associà a menors nivells d’estrès oxidatiu en pacients fumadors actius; (iii) els nivells de ingesta d'àcids grassos _3 i _6 es va relacionar amb els nivells d’inflamació sistèmica; (iv) la ingesta d’embotits i carns curades va incrementar el risc d'hospitalització per MPOC durant el seguiment; i (v) l’adherència a un patró mediterrani d'alimentació s’associà a menor prevalença d'asma infantil. Conclusions: Els hàbits alimentaris poden modificar l'evolució de l'MPOC i el desenvolupament d'asma infantil. Per tant, s’hauria de considerar l’inclusió de consells alimentaris en les guies clíniques per a malalties respiratòries cròniques.
Domenech, Pena Arnau. "Dynamics of Streptococcus pneumoniae in patients with Chronic Obstructive Pulmonary Disease." Doctoral thesis, Universitat de Barcelona, 2013. http://hdl.handle.net/10803/134277.
Full textEn aquesta tesis, es van dur a terme quatre estudis amb l’objectiu d’aprofundir en el paper de S. pneumoniae com a causant d’exacerbacions agudes i pneumònia en pacients amb MPOC. En el primer estudi, es van sembrar quantitativament un total de 188 mostres d’esput obtingudes durant episodis d’EAMPOC en pacients amb MPOC avançat, durant un any d’estudi (febrer 2010 - febrer 2011). S. pneumoniae es va aïllar en 31 (16.5%) episodis i fou la tercera causa d’exacerbació, després de Pseudomonas aeruginosa (28.8%) i Haemophilus influenzae (19.7%). En el segon estudi es va trobar una diferent associació d’alguns serotipus i del seus genotipus relacionats, en pacients amb MPOC amb diferents infeccions pneumocòcciques (període 2001-2008). El serotipus 3 va ser la causa més freqüent de pneumònia i d’EAMPOC, però els serotipus 4 (ST2474), 5 (Colombia5-ST289) i 8 (Netherlands8-ST53) es varen associar amb pneumònia bacterièmica; serotipus 1 (Sweden1-ST306) i 3 (Netherlands3-ST180 i ST2603) es varen associar amb pneumònia tant bacterièmica com no bacterièmica; mentre serotipus 16F (ST3016F), 11A i els pneumococs no-tipificables es varen associar amb EAMPOC (P<0.05). Degut a la implementació de la vacuna conjugada PCV7, els serotipus inclosos en la vacuna han disminuït del 39.4% en el període 2001-2004 a 11.2% en el període 2008-2012. Paral•lelament a aquest descens, els serotipus 15A i 6C han augmentat dramàticament en els últims anys. Per aquesta raó, la multiresistència s’ha mantingut estable durant tot el període d’estudi. En el tercer estudi (1995-2010), es va observar que un terç dels episodis d’EAMPOC recurrents, varen ser causats per una soca preexistent, principalment serotipus 9V i 19F (P<0.05), considerant-se recaigudes. Aquest fet suggereix un paper important del tipus capsular en la persistència. Finalment, es va analitzar l’impacte del consum d’antimicrobians en el desenvolupament de resistència en 13 pacients colonitzats per pneumococc (temps mitjà: 582 dies, DS ±362). Es van observar canvis en les QRDRs de les soques d’aquells pacients que van rebre tractament amb fluoroquinolones. En canvi, les PBPs de les soques persistents van romandre estables tot i els múltiples tractaments amb β-lactàmics que van rebre els pacients. En total, els estudis presentats han millorat el coneixement de la dinàmica de les poblacions de S. pneumoniae i S. pseudopneumoniae en pacients amb MPOC.
Chen, Roy Yu-Wei. "Biomarkers for acute exacerbation of chronic obstructive pulmonary disease." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/57759.
Full textMedicine, Faculty of
Medicine, Department of
Experimental Medicine, Division of
Graduate
McPherson, E. A. "Equine chronic obstructive pulmonary disease (COPD) : publications 1974-1985." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/28607.
Full textSchleifer, Taylor Jacqueline. "Exploring the social construction of chronic obstructive pulmonary disease." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ54197.pdf.
Full textToma, Tudor Paul. "Endoscopic lung volume reduction in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428589.
Full textSaha, Shironjit K. "Inflammatory profiles in chronic obstructive pulmonary disease and asthma." Thesis, University of Leicester, 2010. http://hdl.handle.net/2381/8206.
Full textMoore, Alastair. "Physiological approaches to hyperinflation in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505304.
Full textRickards, Karen Jane. "Neutrophil phosphodiesterase inhibition in equine chronic obstructive pulmonary disease." Thesis, Royal Veterinary College (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251618.
Full textStockley, James. "Neutrophil migration and inflammation in chronic obstructive pulmonary disease." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5999/.
Full textHeneghan, Nicola R. "Chronic obstructive pulmonary disease and cervico-thoracic musculoskeletal dysfunction." Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/4779/.
Full textWalton, Georgia May. "Neutrophil migration and phagocytosis in chronic obstructive pulmonary disease." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8647/.
Full textWainwright, Megan Julie. "Breathing and breathlessness : chronic obstructive pulmonary disease in Uruguay." Thesis, Durham University, 2013. http://etheses.dur.ac.uk/7270/.
Full textHaldar, Kairabi Sadhu. "Profiling of bacterial communities in chronic obstructive pulmonary disease." Thesis, University of Leicester, 2015. http://hdl.handle.net/2381/32292.
Full textCorrell, Amanda Leigh. "Strength training in patients with chronic obstructive pulmonary disease." Winston-Salem, NC : Wake Forest University, 2009. http://dspace.zsr.wfu.edu/jspui/handle/10339/42574.
Full textTitle from electronic thesis title page. Thesis advisor: Michael J. Berry. Includes bibliographical references (p. 49-54).
Jones, Sharon Scardina. "Evaluating a Discharge Bundle for Chronic Obstructive Pulmonary Disease." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/4861.
Full textAkiki, Zeina. "Biological Markers For Chronic Obstructive Pulmonary Disease And Asthma." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS081/document.
Full textStudying the biological markers in chronic obstructive pulmonary disease (COPD) and asthma, two chronic respiratory diseases affecting millions of individuals around the world, could improve their diagnosis, their treatment and their prevention.This thesis includes two parts. The first aimed to assess the association between a lung-specific biomarker, serum Surfactant Protein D (SP-D), and COPD, and to find cut-off points able to discriminate COPD patients from controls using SP-D levels. It was performed in a case-control study in Lebanon including COPD (n=90) and asthma patients (n=124) and controls (n=180). The second part aimed to assess the cross-sectional and longitudinal associations in adults for systemic inflammatory biomarkers (high sensitivity C reactive protein hs-CRP (n=252) and cytokines (n=283) as well as biomarkers of damage due to oxidative stress (8-Isoprostanes 8-IsoPs (n=258) from the exhaled breath condensate) and asthma outcomes.It was performed in the French longitudinal epidemiological study on the genetics and environmental factors of asthma (EGEA).Results showed that serum SP-D levels were positively associated with COPD and thresholds for SP-D levels in these patients were identified with excellent discriminant values. In EGEA, no association was found between serum hs-CRP levels and asthma control. Serum cytokine profiles (identified by principal component analysis) with high levels of interleukin (IL)-1Ra and IL-10 were associated with less asthma attacks and lower risk of poor asthma control in adults seven years later. The results of the preliminary analyses on the associations between the levels of 8-IsoPs and asthma outcomes are also presented.Overall, these results have shown the usefulness of studying the biological markers related to COPD and asthma
Shaikh, Zarrin F. "Patent foramen ovale in obstructive sleep apnoea and chronic obstructive pulmonary disease." Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/9478.
Full textBestall, Janine Caroline. "Outcome of pulmonary rehabilitation in patients with severe chronic obstructive pulmonary disease." Thesis, Queen Mary, University of London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322237.
Full textBrazil, Timothy John. "Pulmonary neutrophil recruitment, activation and clearance in equine chronic obstructive pulmonary disease." Thesis, University of Edinburgh, 2000. http://hdl.handle.net/1842/29982.
Full textKoreny, Maria 1972. "Determinants of physical activity behaviour in patients with chronic obstructive pulmonary disease." Doctoral thesis, TDX (Tesis Doctorals en Xarxa), 2021. http://hdl.handle.net/10803/671432.
Full textAntecedentes: Aunque la actividad física es clave para mejorar el pronóstico en pacientes con enfermedad pulmonar obstructiva crónica (EPOC), todavía no se dispone de información que permita adaptar las intervenciones de manera individualizada. El objetivo de la presente tesis es comprender la progresión de la actividad física y explorar sus determinantes en pacientes con EPOC. Métodos: Utilizamos datos basales y de seguimiento (12 meses) de 643 pacientes con EPOC estable de estadio leve a muy grave, procedentes de dos estudios europeos multicéntricos. Evaluamos: actividad física (Dynaport MoveMonitor), experiencia de actividad física (Clinical visit-PROactive physical activity in COPD [C-PPAC]), capacidad funcional de ejercicio (distancia caminada en la prueba de la marcha de 6 minutos [6MWD]) y variables sociodemográficas, interpersonales, ambientales, clínicas y psicológicas. Resultados: (1) La progresión natural de la actividad física a lo largo del tiempo fue heterogénea y se pudieron identificar tres patrones distintos: inactivo, activo que aumenta y activo que reduce. Mientras que el patrón de pacientes inactivo se relacionaba con peores características clínicas de la EPOC, no se pudo predecir la evolución de los activos a aumentar o reducir; (2) la mayor densidad de población y la exposición a largo plazo al NO2 se asociaron desfavorablemente con la actividad física, mientras que una mayor pendiente del terreno se relacionó con una mejor capacidad de ejercicio; (3) la compleción a los 12 meses con una intervención de actividad física conductual estuvo determinada por los hábitos de actividad física previos, así como por facilitadores interpersonales y ambientales, mientras que la respuesta a la intervención se relacionó con diversos factores asociados a la motivación para cambiar a un estilo de vida activo. Conclusiones: Esta tesis muestra que la progresión natural de la actividad física en los pacientes con EPOC es heterogénea y destaca que los factores ambientales, interpersonales y psicológicos son importantes determinantes de la actividad física en los pacientes con EPOC, más allá de los factores clínicos. Resum Antecedents: Malgrat el paper clau de l’activitat física per millorar el pronòstic en pacients amb malaltia pulmonar obstructiva crònica (MPOC), encara no disposem d’informació que permeti individualitzar les intervencions. L’objectiu d’aquesta tesi és entendre la progressió de l’activitat física i explorar-ne els determinants en pacients amb MPOC.
Jansson, Sven-Arne. "Health economic epidemiology of obstructive airway diseases : the obstructive lung disease in northern Sweden studies - thesis VII /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-805-3/.
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