Relevant bibliographies by topics / Chirayita

Academic literature on the topic 'Chirayita'

Author: Grafiati
Published: 18 May 2024

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Journal articles on the topic "Chirayita"

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Singh, Nilay, Neetu Sharma, Promila Sharma, Bhawana ., and Bindu Agarwal. "Review of critically endangered medicinal plant Swertia chirayita for developing conservation strategies." Journal of medical pharmaceutical and allied sciences 11, no. 2 (March 30, 2022): 4552–59. http://dx.doi.org/10.55522/jmpas.v11i2.2074.

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AMedicinal plants always play an important role in pharmaceutical applications. Swertia chirayita is one of the chief plants of the Gentianeace family. It is a potent drug used in Ayurveda, Siddha, and Homoeopathy in many formulations and is efficient in the healing of a range of diseases. The foremost emphasis of this assessment is in the direction of evaluating the versatile, multi-potential medicinal use of Swertia chirayita and updating information about pharmacognostical, phytochemical, and pharmacological studies. Swertia chirayitais has extensive types of characteristics, such as antibacterial activity, antifungal activity, antioxidant activity, etc. The current scenario and condition of this plant show that the prevailing number of these species is ebbing at a very great proportion. So, there must be different efficient conservation and sustentation strategies that can be put into effect for the preservation of this plant in its natural ecosystem. If felicitous methods are not augmented and employed, the extinction of these species cannot be ruled out anytime soon in the future. So, at this critical stage, there must be some urgent and active conservation strategies to be implemented at the earliest possible date. Keywords: Swertia chirayita, Gentianaceae, Chemical composition, Amarogentine, Pharmacological.
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Shrestha, Sangita, Jaishree Sijapati, Neesha Rana, Diwa Malla, Prabha Regmi, and Bhakta Raskoti. "Optimization of RAPD-PCR conditions for the study of genetic diversity in Nepal’s Swertia chirayita (Roxb. Ex Fleming) H. Karst." Himalayan Journal of Sciences 6, no. 8 (June 28, 2011): 35–40. http://dx.doi.org/10.3126/hjs.v6i8.2699.

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Of the 30 species (including five varieties) of the genus Swertia in Nepal, nine have been reported to possess medicinal properties. Among these, S. chirayita is the most valuable species, with high demand in domestic and international markets. Nepal’s S. chirayita and related species are being recklessly exploited for commercial purposes. Two problems that have emerged with this lucrative market are (a) adulteration and fraudulent labeling of S. chirayita, and (b) depletion of S. chirayita and allied species from their natural habitats. To address the problem of adulteration and conservation, we studied molecular genetic diversity in S. chirayita populations and developed a molecular diagnostic tool for the purposes of authentication. We studied intra-specific genetic diversity in S. chirayita using Polymerase Chain Reaction (PCR)-based Random Amplified Polymorphic DNA (RAPD) technique. As a preliminary step, we identified optimal RAPD-PCR reaction and cycling conditions by varying PCR reaction parameters such as concentration of template DNA, MgCl2, dNTPs, primer, Taq DNA polymerase and RAPD-PCR programs. The optimized PCR reaction and cycling conditions were then used in subsequent RAPD profiling experiments for the study of genetic diversity within S. chirayita populations from various geographical locations. Genetic diversity characterization of S. chirayita populations at the molecular level would furnish information with significant applications in the conservation and sustainable utilization of S. chirayita and its allied species in Nepal. Key words: Polymerase Chain Reaction, Random Amplified Polymorphic DNA, DNA fingerprinting, genetic diversity DOI: http://dx.doi.org/10.3126/hjs.v6i8.2699 Himalayan Journal of Sciences Vol.6 Issue 8 2010 pp.35-40
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Rabgyal, Jimba, Yadunath Bajgai, Karma Pelden, Tshering Tobgay, and Sonam Rinchen. "Assessment of Nursery Methods and Manures for Cultivation of Chirayita (Swertia chirayita Buch-Ham.) in Lauri Gewog, Bhutan." Bhutanese Journal of Agriculture 4, no. 1 (February 24, 2021): 137–51. http://dx.doi.org/10.55925/btagr.21.4112.

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Chirayita (Swertia chirayita) is a medicinal plant and is native to the temperate Himalayas. It is widely used in traditional and modern medicines with an increased global demand, leading to unsustainable harvesting, causing the decline, and critically endangering the species. Hence, we hypothesized that chirayita could be domesticated and tested this hypothesis at Lauri Gewog in southeastern Bhutan. Four nursery methods and four organic manure treatments were tested using Completely Randomized Design with three replicates. The average seedling density across the four treatments at mid altitude was 2356 seedlings/m2, and that of high altitude was 1202 seedlings/m2. The seedling density at mid altitude was 96% higher compared to that of high altitude; however, there were significant differences between the treatments only in high altitude (P = 0.003) and not in mid altitude. The methods were non-significant at mid altitude, mainly due to the large variability of data. Interestingly, the manure treatments were not significant compared to the control implying that the chirayita could be non-responsive to the application of manures in the study conditions. Fresh weight of chirayita in the control plot was 14, 19 and 29% higher than ‘compost’, ‘FYM’ and ‘compost+FYM (1:1)’ treatment plots. Further, this research provides an alternative low-cost nursery technique for adoption by chirayita farmers while also providing information for policymakers and environmental conservationists in developing strategies for conservation of a critically endangered species like chirayita.
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Phoboo, Susanna, Dipayan Sarkar, Prasanta C. Bhowmik, Pramod Kumar Jha, and Kalidas Shetty. "Improving salinity resilience in Swertia chirayita clonal line with Lactobacillus plantarum." Canadian Journal of Plant Science 96, no. 1 (February 1, 2016): 117–27. http://dx.doi.org/10.1139/cjps-2015-0178.

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Plants defense responses to abiotic stresses, including salinity stress, involve stimulation of defense related pathways such as biosynthesis of secondary metabolites and induction of endogenous antioxidant enzyme responses. In the present study, a single seed origin clonal line of Swertia chirayita inoculated with Lactobacillus plantarum (LP) was grown under different salinity levels. Control had no LP inoculation. S. chirayita inoculated with LP showed higher accumulation of proline, low proline dehydrogenase activity, up-regulation of pentose phosphate pathway, down-regulation of succinate dehydrogenase activity (Krebs cycle) and low total phenolic content with increased salt concentrations. In comparison, S. chirayita without LP adopted a different biochemical mechanism to counter salt stress (NaCl) by up-regulating both pentose phosphate pathway and Krebs cycle along with stimulation of phenolic biosynthesis. Guaiacol peroxidase (GPX) activity increased with and without LP treatment in response to increasing concentrations of salt. These results indicate that S. chirayita inoculated with LP exhibits a greater salinity stress tolerance than S. chirayita without LP by adopting a more energy efficient defense responses and potentially efficiently partitioning carbon flux between primary and secondary metabolism to counter salt induced oxidative stress.
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Thapa, Rabindra, and Sanjay Kumar Jha. "Study of fungal diseases on Swertia chirayita from cultivated fields of Dolakha district, central Nepal." Our Nature 20, no. 1 (June 6, 2022): 41–47. http://dx.doi.org/10.3126/on.v20i1.44951.

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Swertia chirayita is a medicinally and economically important herb of the family Gentinaceae. It is one of the highly traded, traditionally important medicinal plants. Fungal Pathogens corrupt the quality and amount of Swertia chirayita development, and production and cause terrible well-being of plants as well as monetary problem to the traders. This study was carried out to identify some diseases associated with S. chirayita cultivated fields in Bigu, Khartal, and Boch regions of Dolakha district. The samples were collected from selected sites and cultured on Potato Dextrose Agar media for fungal pathogens. During the investigation, five species of fungal pathogens were identified. Alternaria alternata, Colletotrichum gleosporioides and Curvularia sp. were isolated from leaf. They caused Alternaria leaf spot, Colletotrichum leaf blight, and Curvularia leaf spot. Similarly, stem possesses canker disease and root had root canker, Fusarium oxysporum causing Fusarium wilt, Rhizoctonia sp. causing Rhizoctonia root rot. The presence of illnesses in S. chirayita shows the need for proper plant care.
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Khanal, Supreet, N. Shakya, N. Nepal, and D. Pant. "Swertia chirayita: The Himalayan Herb." International Journal of Applied Sciences and Biotechnology 2, no. 4 (December 25, 2014): 389–92. http://dx.doi.org/10.3126/ijasbt.v2i4.11281.

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Swertia chirayita is a native Himalayan herb typically found in the altitude of 1500 to 3100m. Swertia species are commonly used as primary medicines in fever, digestive and enteric diseases; especially S. chirayita is of principal importance. The pharmacological and ethno-medicinal perspective of the plant is well understood traditionally and pharmaceutically. Its secondary metabolites including glycosides and xanthones show promising bioactivity making it a powerful herb. Mixing of Swertia chirayita with its other species is done routinely in chiretta trade. Extensive wild collection and lack of sustainable conservation has led to the vulnerable status of the wild cultivar. DOI: http://dx.doi.org/10.3126/ijasbt.v2i4.11281 Int J Appl Sci Biotechnol, Vol. 2(4): 389-392
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Rehman, Sumbul. "Antimutagenic Effect of Medicinal Plants from Alternative Medicine." International Journal of Pharmacognosy & Chinese Medicine 5, no. 1 (2021): 1–7. http://dx.doi.org/10.23880/ipcm-16000216.

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Aqueous extracts of Chirayita (Swertia chirayita Linn.) whole herb, Banafshah (Viola odorata Linn.) leaves and flowers and Mameeran (Coptis teeta Roxb.) rhizome were tested for their anti-mutagenic potential by Ames Salmonella Histidine point mutation assay of Maron, et al. with partial modifications as described by Kaur, et al. At a dose of 50 μg/plate, crude drug extracts exhibited the inhibition of His+ revert ants from 36.59% to 96% against direct acting mutagen sodium azide (NaN3) which induced mutagenicity in Salmonella typhimurium tester strains TA97a, TA98 and TA100. However, at concentrations (5 and 25 µg/ plate) of the plant extracts, a significant decrease in anti-mutagenic activity was recorded. In the present findings, herbal drug extracts at tested concentrations showed no sign of mutagenicity to the tester strains. Potent anti-mutagenic activity of Banafshah was observed followed by Chirayita and Mameeran. Linear regression analysis of the data shows dose dependent anti-mutagenic activity of the extracts. Qualitative analysis reveals the presence of active phytochemical as amarogentin, mangiferin (Chirayita), Cyclotides (Banafshah), Berberine (Mameeran) along with other phyto-constituents flavonoids, phenols in the tested extracts which are responsible for their anti-mutagenic activity.
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Qura-Tul-Ain, Sidra Mushtaq, Naveeda Manzoor, Mahreen Akhtar, Anila Errum, and Naseem Saud Ahmad. "Comparison of Xanthine Oxidase Inhibitory Effect of Swertia chirayita and Febuxostat in Vitro." Proceedings 35, no. 2 (April 21, 2021): 18–22. http://dx.doi.org/10.47489/pszmc784-35-2-18-22.

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Introduction:Plasma uric acid ? 6.5 to 7.0 mg/dl increases the incidence of gout, hypertension, diabetes mellitus type 2, stroke and heart failure. Low purine diet, use of xanthine oxidase inhibitors allopurinol and febuxostat; or uricosuric agent’s probenecid, sulfinpyrazone and Benzbromarone are being used for treatment. Swertia chirayita extract (SCE) being practiced as anti-inflammatory and anti-oxidant was evaluated for inhibition of xanthine oxidase. Aims & Objectives: To observe the in vitro effect of Swertia chirayita ethanolic extract on xanthine oxidase inhibition and its comparison with medicine febuxostat. Place and duration of study: The study was conducted in Pharmacology Department, University of Health Sciences Lahore during June-August 2017. Material & Methods: Xanthine oxidase (XO) inhibition by ethanolic extract of the herb was compared with febuxostat. Serial dilutions of test compounds ranging from 1.25µg/ml to 100 µg/ml were prepared in absolute ethanol. Fixed volumes of xanthine, xanthine oxidase, phosphate buffer and test compounds were incubated. Uric acid concentration in the reaction mixture was calculated by measuring absorbance at 295nm by using Ultraviolet- Visible Spectrophotometer. Mean values and percent inhibition (± SD) was calculated. EZ Fit Enzyme Kinetic program was also used to calculate inhibitory concentration 50 percent (IC50), Michaelis constant (Km) and maximum rate of reaction (Vmax). Results: At maximum dose, (100 µg/ml) xanthine oxidase inhibition by febuxostat and Swertia chirayita was 98% and 80% percent respectively (p=0.01). Swertia chirayita extract showed IC50 at 9.15± 1.2 µg/ml whereas IC50 of febuxostat was 7.91± 0.9 µg/ml. Conclusion: In the light of XO inhibition, Swertia chirayita has potential to be explored as antihyperuricemic agent.
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Asthana, Rakesh K., Narendra K. Sharma, Dinesh K. Kulshreshtha, and Sunil K. Chatterjee. "A xanthone from Swertia chirayita." Phytochemistry 30, no. 3 (January 1991): 1037–39. http://dx.doi.org/10.1016/0031-9422(91)85308-m.

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R, Rastogi. "An Analytical Study of Kalmegh (Andrographis Paniculata) and Kiratikta (Swertia Chirayita): An Economic Substitution for Metro Cities in Global Pandemic with Healthcare 4.0." Journal of Natural & Ayurvedic Medicine 6, no. 2 (April 29, 2022): 1–16. http://dx.doi.org/10.23880/jonam-16000346.

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Ayurveda has always been a treasure of knowledge. During Covid pandemic when humans were forced to suffer and no cure seemed to exist to end this suffering, the Ayurvedic medicine system once again proved its viability and brought our sufferings to the end. Many Ayurvedic herbs showed a wondrous effect in the treatment of Covid. One of those is S. chirayita, It is famous formulation Sudarshan Ghan Vati and AYUSH-64 were found very effective in Covid treatment. It is very unfortunate for us that such a potent herb has now become endangered. In this manuscript the core idea is to substantiate that the Andrographis paniculata, another indigenous herb, can be a wellfounded substitute for Swertia chirayita. The authentic quality of A. paniculata can be fetched from the market with economic prices having the substitutable pharmacological effect as compared with S. chirayita, however the authenticity of S. chirayita is doubtful due to the endangered status of this herb. In this work, authors have made a comparative study between both drugs. For this, a systematic review of literature and a pharmacogonostical study was done. On investigation, it was found that both drugs are almost similar in qualitative phytochemical analysis and qualities as par Ayurvedic pharmacology. It was also observed that most of the therapeutic actions of both drugs are similar. Graphical and tabular representation of the different parameters gives more insight to the readers. Use of pictures has also been done to heighten the interest of readers. Background: Along with the abundant erudition of medicines Ayurveda also provides to us vast fields for research purposes. Kiratatikta i.e. Swertia chirayita found in the Himalayan regions had been frequently described in the Ayurvedic literature because of it is unique viability as a medicinal herb. On the other hand Andrographis paniculata commonly known as kalmegh is found in the plain regions of the Indian subcontinent. The respective drug had been used therapeutically for ages by the indigenous people of Asian and European countries. Swertia chirayita (Kiratatikta) and Andrographis paniculata (Kalmegha) both are widely used herbs with high medicinal value. These are being used by Ayurvedic physicians in different diseases, such as (jvara) fever, (Krimi) worm infestation, (Vrana) wound, and (Kushtha) skin diseases. Modern studies have also explicitly revealed that both these herbs have a wide range of pharmacological actions such as antipyretic, antimalarial, anti-inflammatory, antidiarrhoeal, antiviral, hepatoprotective, antidiabetic, anticancer, anti-human immunodeficiency virus (HIV), and immune stimulator. Sudarshan Ghan Vati and AYUSH-64 which were found very effective in Covid-19 treatment are famous formulations of S. chirayita. Recently A. paniculata also has been very popular among pharmaceuticals. During the pandemic, it has been found effective in the treatment of Covid-19. The aim of this work is to compare both the drugs through literary review and pharmacogonostical analysis so that we can assess whether A. paniculata can be used as a substituent drug to S. chirayita or not. Because S. chirayita is not only very costly but also an endangered species making its availability harder for common use. On the other hand, Kalmegh i.e. A. paniculata not only is cheap and cost- effective but can also be grown anywhere easily just like a weed making it much more feasible. A detailed study is provided in the manuscript, describing elaborate analysis. Organization of the Paper: This study, first of all, gives a general idea of global health in today's time and the adverse effects of modern medicine to manage covid-19 pandemic. The author team explained about Ayurveda and its holistic approach. For the endorsement of the study, the author team initially did a literary survey and reviewed research papers of concerned drugs and various Ayurvedic texts like Charak Samhita, Sushruta Samhita, Ashtang Samgrah, Raj Nighantu, Bhavprakash nighantu, Dhanvantari Nighantu, Priya nighantu, Adarsh nighantu, Dravyaguna Vigyan, etc. This literary survey provides deep knowledge about both drugs i.e. Kiratatikta and Kalmegha. The author team has described the methodology in which they have represented the methods used for the study. This study has been divided into two sections, the first was a literature review and the second was a pharmacogonostical screening of both plant samples. After critical analysis of pharmacognostical screening results were presented. The manuscript presents all data in graphical and tabular form as well. In the recommendation section, which is one of the most important parts of the research studies, suggestions for specific interventions to address the issues and constraints identified in the assessment have been presented. The novelty section refers to elements that are new in the research. In the last, the conclusion section represents the final assessment and describes the overall findings of the study. Motivation of the Study: In the terrifying time of COVID pandemic, when the whole of mankind was looking for a miracle, Ayurveda proved to be a boon for our survival. Formulations like Sudarshan Ghan Vati and AYUSH-64, gave positive results against Covid-19. The main ingredient of this formulation is Kiratatikta i.e. S. chirayita. The main motivation of this study is to find an economical substitute for S. chirayita and as well as preservation of S. chirayita, as it is a critically endangered medicinal herb now.
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Dissertations / Theses on the topic "Chirayita"

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Pradhan, Sabina. "Studies on physiology and bio chemistry of swertia chirayita (Roxb) karsten in Darjeeling hills: influence of plant growth - substances on growth, metabolism and - yield." Thesis, University of North Bengal, 2015. http://ir.nbu.ac.in/hdl.handle.net/123456789/1846.

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Pradhan, Bharat Kumar. "Population studies and habitat characteristics of swertia chirayita (Roxb. ex Fleming) H. Karst. , a threatened Medicinal Herb in Sikkim Himalaya, and Its Conservation." Thesis, University of North Bengal, 2011. http://hdl.handle.net/123456789/1434.

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Books on the topic "Chirayita"

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Agnihotri, Anita. Chirayata. Calcutta: Sahityam, 2001.

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GREEK KABITA: CHIRAYATO, SOMOKALIN. KOLKATA: PATROLEKHA, 2012.

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Book chapters on the topic "Chirayita"

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Dev, Sukh. "Swertia chirayita." In Prime Ayurvedic Plant Drugs, 652–60. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-22075-3_93.

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Mazumder, Md Anisur Rahman, Md Fahad Jubayer, Mohammad Javed Ansari, and Thottiam Vasudevan Ranganathan. "Swertia chirayita (Roxb. ex Flem.): Chirayata/Chiretta." In Immunity Boosting Medicinal Plants of the Western Himalayas, 511–39. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-9501-9_21.

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Khare, C. P. "Swertia chirayita (Roxb. ex Flem.) Karst." In Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_1572.

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Meena, Poonam, Sampat Nehra, and P. C. Trivedi. "Anthology of Chemical Diversity of Bioactive Molecules and Therapeutics of the Genus Swertia chirayita (Roxb. ex Flem.) Karsten (Syn. Gentiana chirayita Roxb. ex Flem.)." In Bioactives and Pharmacology of Medicinal Plants, 105–20. Boca Raton: Apple Academic Press, 2022. http://dx.doi.org/10.1201/9781003281658-8.

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Dhyani, Praveen, Lalit Giri, Eshita Sharma, and Priyanka Sati. "Swertia chirayita, an Endangered Anti-diabetic Plant: Trends in Biotechnological Interventions." In Biotechnology of Anti-diabetic Medicinal Plants, 133–51. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-3529-8_6.

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Akbar, Shahid. "Swertia chirata Buck.-Ham. ex Wall. Swertia chirayita (Roxb.) H. Karsten (Gentianaceae)." In Handbook of 200 Medicinal Plants, 1699–707. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-16807-0_176.

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Chaudhuri, Rituparna Kundu, and Dipankar Chakraborti. "Bioactive Compounds from In-Vitro Culture of Swertia Chirayita (Roxb. Ex Flem.) Karsten: Identification and Quantification." In Plant-Based Functional Foods and Phytochemicals, 311–34. Series statement: Innovations in plant science for better health : from soil to fork: Apple Academic Press, 2020. http://dx.doi.org/10.1201/9781003055419-10.

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Timilsina, Bishnu, Rabindra Parajuli, Dilli Prasad Rijal, Ripu M. Kunwar, Hammad Ahmad Jan, Wahid Hussain, Rainer W. Bussmann, and Narel Y. Paniagua-Zambrana. "Swertia angustifolia Burkill Swertia chirayita Buch.-Ham. ex C.B. Clarke Swertia cordata (G.Don) Clarke Swertia petiolata D. Don Gentianaceae." In Ethnobotany of the Himalayas, 1–12. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-45597-2_237-1.

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Jan, Hammad Ahmad, Wahid Hussain, Rainer W. Bussmann, and Narel Y. Paniagua-Zambrana. "Swertia angustifolia Burkill Swertia chirayita Buch.-Ham. ex C.B. Clarke Swertia cordata (G.Don) Clarke Swertia petiolata D. Don Gentianaceae." In Ethnobotany of the Himalayas, 1–10. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-45597-2_237-2.

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Jan, Hammad Ahmad, Wahid Hussain, Rainer W. Bussmann, and Narel Y. Paniagua-Zambrana. "Swertia angustifolia Burkill Swertia chirayita Buch.-Ham. ex C.B. Clarke Swertia cordata (G. Don) Clarke Swertia petiolata D. Don Gentianaceae." In Ethnobotany of the Himalayas, 1943–52. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57408-6_237.

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Conference papers on the topic "Chirayita"

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Rutz, Adriano, Pascale Deneulin, Ivano Tonutti, Benoît Bach, and Jean-Luc Wolfender. "Untargeted chemical and sensory characterization of Swertia chirayita: a bitter case study." In GA – 69th Annual Meeting 2021, Virtual conference. Georg Thieme Verlag, 2021. http://dx.doi.org/10.1055/s-0041-1736968.

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