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1

Yamada, Naomi, William K. M. Lai, Nina Farrell, B. Franklin Pugh, and Shaun Mahony. "Characterizing protein–DNA binding event subtypes in ChIP-exo data." Bioinformatics 35, no. 6 (August 28, 2018): 903–13. http://dx.doi.org/10.1093/bioinformatics/bty703.

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Abstract Motivation Regulatory proteins associate with the genome either by directly binding cognate DNA motifs or via protein–protein interactions with other regulators. Each recruitment mechanism may be associated with distinct motifs and may also result in distinct characteristic patterns in high-resolution protein–DNA binding assays. For example, the ChIP-exo protocol precisely characterizes protein–DNA crosslinking patterns by combining chromatin immunoprecipitation (ChIP) with 5′ → 3′ exonuclease digestion. Since different regulatory complexes will result in different protein–DNA crosslinking signatures, analysis of ChIP-exo tag enrichment patterns should enable detection of multiple protein–DNA binding modes for a given regulatory protein. However, current ChIP-exo analysis methods either treat all binding events as being of a uniform type or rely on motifs to cluster binding events into subtypes. Results To systematically detect multiple protein–DNA interaction modes in a single ChIP-exo experiment, we introduce the ChIP-exo mixture model (ChExMix). ChExMix probabilistically models the genomic locations and subtype memberships of binding events using both ChIP-exo tag distribution patterns and DNA motifs. We demonstrate that ChExMix achieves accurate detection and classification of binding event subtypes using in silico mixed ChIP-exo data. We further demonstrate the unique analysis abilities of ChExMix using a collection of ChIP-exo experiments that profile the binding of key transcription factors in MCF-7 cells. In these data, ChExMix identifies possible recruitment mechanisms of FoxA1 and ERα, thus demonstrating that ChExMix can effectively stratify ChIP-exo binding events into biologically meaningful subtypes. Availability and implementation ChExMix is available from https://github.com/seqcode/chexmix. Supplementary information Supplementary data are available at Bioinformatics online.
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2

Giménez de la Peña, Almudena, Miguel López-Zamora, Oscar Vila, Auxiliadora Sánchez, and Lisa B. Thorell. "Validation of the Spanish version of the Childhood Executive Functioning Inventory (CHEXI) in 4-5 year-old children." Anales de Psicología 38, no. 1 (January 1, 2022): 101–9. http://dx.doi.org/10.6018/analesps.453171.

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Background: The Childhood Executive Functioning Inventory (CHEXI) was designed to identify EF deficits in daily life contexts. The aim of the present study was to validate the Spanish version of the CHEXI in 4-5-year-old children. Method: Parents’ ratings of the CHEXI and laboratory tests of EF were investigated in two large samples of 445 children aged 4 years (196 girls, 249 boys) and 459 children aged 5 years (208 girls, 251 boys). CHEXI ratings were collected again after one-year. Results: The two-factor structure of the CHEXI (i.e., Working Memory and Inhibition) was replicated, showing high internal consistency and temporal stability. The 4-year-olds were reported to have higher EF deficits than 5-year-olds have. Boys were rated as having higher EF deficits than girls were. However, gender differences were not significant contrasting performance on EF tasks. Finally, associations between CHEXI ratings and EF tests were weak, suggesting that EF tests and EF ratings capture different aspects of EF. Conclusions: The Spanish CHEXI provides a suitable instrument to assess EF in 4-5-year-old children. Contexto: El Childhood Executive Functioning Inventory (CHEXI) se diseñó para detectar déficit de Funciones Ejecutivas (FE) en contextos de la vida diaria. El propósito del presente estudio era validar la versión española del CHEXI para niños de 4 y 5 años. Método: Se obtuvieron las valoraciones de los padres y las puntuaciones en test de laboratorio en una muestra de 445 niños de 4 años (196 niñas, 249niños) y otra de 459 niños de 5 años (208 niñas, 251 niños). Un año más tarde se volvieron a recoger las valoraciones de los padres en CHEXI. Resultados: Se replicó la estructura de dos factores de CHEXI (Memoria de Trabajo e Inhibición), obteniendo una alta consistencia interna y estabilidad temporal. Los niños de 4 años eran valorados con mayor déficit en FE que los niños de 5 años. Los niños alcanzaban puntuaciones más elevadas de déficit de FE. Sin embargo, no aparecieron diferencias significativas de género en las pruebas conductuales. Finalmente, se encontró una baja asociación entre las valoraciones de CHEXI y las puntuaciones de las pruebas conductuales. Este resultado sugiere que los inventarios y las medidas conductuales evalúan diferentes aspectos de las FE. Conclusiones: La versión española de CHEXI ofrece un instrumento válido para evaluar las FE en niños de 4 y 5 años.
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3

Catale, Corinne, Caroline Lejeune, Sarah Merbah, and Thierry Meulemans. "French Adaptation of the Childhood Executive Functioning Inventory (CHEXI)." European Journal of Psychological Assessment 29, no. 2 (May 1, 2013): 149–55. http://dx.doi.org/10.1027/1015-5759/a000141.

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Thorell and Nyberg (2008 ) recently developed the Childhood Executive Functioning Inventory (CHEXI), a new rating instrument for executive functioning in day-to-day life which can be divided into four subscales: working memory, planning, inhibition, and regulation. Using an exploratory factor analysis on data from young Swedish children attending kindergarten, Thorell and Nyberg (2008 ) found a two-factor solution that taps working memory and inhibition. In the present study, we explored the psychometric characteristics of the French adaptation of the CHEXI. A group of 95 parents of 5- and 6-year-old children completed the CHEXI, 87 of whom were given clinical inhibition and working memory tasks. Confirmatory factor analyses confirmed the two-factor solution based on inhibition and working memory that was identified in the original study of Swedish children. Supplementary results indicated good internal and test-retest reliability for the entire scale, as well as for the two subscales identified. Correlation analyses showed no relationship between cognitive measures and the CHEXI subscales. Possible clinical applications for the CHEXI scales are discussed.
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Trevisan, Bruna Tonietti, Natália Martins Dias, Arthur de Almeida Berberian, and Alessandra Gotuzo Seabra. "Childhood Executive Functioning Inventory: Adaptação e Propriedades Psicométricas da Versão Brasileira." Psico-USF 22, no. 1 (April 2017): 63–74. http://dx.doi.org/10.1590/1413-82712017220106.

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Resumo O objetivo do estudo foi traduzir, adaptar e investigar propriedades psicométricas da Childhood Executive Functioning Inventory (CHEXI) em uma amostra de crianças brasileiras. Após tradução, adaptação transcultural, retrotradução e equivalência semântica, realizada por juízes da área, a versão brasileira da CHEXI foi respondida por pais e professores de 408 crianças, idades entre 4 e 7 anos, também avaliadas com a Escala de Maturidade Mental Colúmbia e SNAP-IV. Elevados índices de consistência interna foram encontrados. A análise fatorial exploratória gerou dois fatores para a versão brasileira: um fator mais geral de funções executivas e um específico de inibição. As pontuações nas subescalas de planejamento, regulação e, marginalmente, memória de trabalho da CHEXI explicaram de modo significativo o indicador de desatenção da SNAP-IV, enquanto a pontuação na subescala de inibição explicou o indicador de hiperatividade/impulsividade. Os resultados fornecem bons parâmetros psicométricos para a CHEXI, além de contribuir para a realização de estudos com funções executivas e indicadores de TDAH no país.
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Yamada, Naomi, Prashant Kumar Kuntala, B. Franklin Pugh, and Shaun Mahony. "ChExMix: A Method for Identifying and Classifying Protein–DNA Interaction Subtypes." Journal of Computational Biology 27, no. 3 (March 1, 2020): 429–35. http://dx.doi.org/10.1089/cmb.2019.0466.

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6

Moest, W. T., C. Kruydenberg, M. Tan, and T. Koster. "X-ChEXIT in screening for occult cancer in patients with a deep vein thrombosis." European Journal of Internal Medicine 42 (July 2017): e9-e10. http://dx.doi.org/10.1016/j.ejim.2017.04.007.

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7

Józsa, Gabriella, and Krisztián Józsa. "A gyermekkori (CHEXI) és a felnőttkori (ADEXI) végrehajtó funkció kérdőívek magyar nyelvre történő adaptációja." Magyar Pedagógia 120, no. 1 (2020): 47–69. http://dx.doi.org/10.17670/mped.2020.1.47.

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8

Thorell, Lisa B., and Lilianne Nyberg. "The Childhood Executive Functioning Inventory (CHEXI): A New Rating Instrument for Parents and Teachers." Developmental Neuropsychology 33, no. 4 (June 26, 2008): 536–52. http://dx.doi.org/10.1080/87565640802101516.

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9

Sun, Jianping, Hongjian Zhang, and Chunyan Lin. "Source Rocks and Petroleum Reservoirs in the Chexi Sunken of the Jiyang Depression, China." Energy Exploration & Exploitation 24, no. 3 (June 2006): 151–59. http://dx.doi.org/10.1260/014459806779367482.

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10

Thorell, Lisa B., Lilianne Eninger, Karin C. Brocki, and Gunilla Bohlin. "Childhood Executive Function Inventory (CHEXI): A promising measure for identifying young children with ADHD?" Journal of Clinical and Experimental Neuropsychology 32, no. 1 (January 15, 2010): 38–43. http://dx.doi.org/10.1080/13803390902806527.

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11

Camerota, Marie, Michael T. Willoughby, Laura J. Kuhn, and Clancy B. Blair. "The Childhood Executive Functioning Inventory (CHEXI): Factor structure, measurement invariance, and correlates in US preschoolers." Child Neuropsychology 24, no. 3 (November 13, 2016): 322–37. http://dx.doi.org/10.1080/09297049.2016.1247795.

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12

Latorre-Román, Pedro Ángel, Mireya Palomero-Ramirez, Lourdes Cañizares-Ortega, Carmen Latorre-Sevilla, Jesús Salas-Sánchez, and Manuel Pulido-Martos. "Propiedades Psicométricas de la Versión Española del Cuestionario CHEXI de Funcionamiento Ejecutivo en Niños Preescolares." Revista Iberoamericana de Diagnóstico y Evaluación – e Avaliação Psicológica 68, no. 2 (April 2023): 5. http://dx.doi.org/10.21865/ridep68.2.01.

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13

Gutierrez, Marisel, Vanessa Arán Filippetti, and Viviana Lemos. "The Childhood Executive Functioning Inventory (CHEXI) Parent and Teacher Form: Factor Structure and Cognitive Correlates in Spanish-speaking Children from Argentina." Developmental Neuropsychology 46, no. 2 (January 22, 2021): 136–48. http://dx.doi.org/10.1080/87565641.2021.1878175.

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14

Risso, Alicia, Manuel García, Montserrat Durán, Juan Carlos Brenlla, Manuel Peralbo, and Alfonso Barca. "Un análisis de las relaciones entre funciones ejecutivas, lenguaje y habilidades matemáticas." Revista de Estudios e Investigación en Psicología y Educación, no. 09 (September 21, 2015): 073. http://dx.doi.org/10.17979/reipe.2015.0.09.577.

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El objetivo de este trabajo fue explorar la relación existente entre un conjunto de variables cognitivo-lingüísticas, como son la conciencia fonológica, la competencia lectora y matemática, y las funciones ejecutivas en las etapas iniciales de escolarización. Tanto las variables cognitivas como las lingüísticas analizadas tienen una alta dependencia de las funciones ejecutivas que permiten la planificación y supervisión intencional del comportamiento. Dos de los procesos más importantes implicados son los que nuclean el modelo de Miyake. Determinar la influencia que estos procesos de arriba-abajo tienen sobre el rendimiento cognitivo-lingüístico puede ser un objetivo interesante desde el punto de vista de la evaluación de las dificultades de aprendizaje en la escuela. Con la finalidad de hacer un estudio exploratorio se seleccionaron 16 niños y niñas 2º de Educación Primaria de un colegio público con edades comprendidas entre los 7 y 8 años. Los datos sobre conciencia fonológica y competencia lectora fueron obtenidos a través del LOLEVA, los relacionados con las Funciones ejecutivas se obtuvieron a través del CHEXI cubierto por el profesorado, y el índice de competencia matemática (ICM) se obtuvo a través del TEMA-3. Los resultados muestran que tanto las medidas cognitivas, como las lingüísticas tienen una alta correlación con las funciones ejecutivas evaluadas, pero no en todas las tareas ni con el mismo peso. De igual modo, entre las medidas de los dominios lingüístico y matemático parecen existir relaciones claramente significativas, posiblemente mediadas por su dependencia básica de las funciones ejecutivas.
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15

Jennings, Mark, Aoife Guilfoyle, James Green, Yvonne Cleary, and Rosemary Joan Gowran. "Octopus Watch Fosters Family Resilience by Enhancing Occupational Engagement for Children with Spina Bifida and/or Hydrocephalus: Pilot Study." International Journal of Environmental Research and Public Health 17, no. 22 (November 10, 2020): 8316. http://dx.doi.org/10.3390/ijerph17228316.

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Background: Children with spina bifida and/or hydrocephalus (SB&/H) often experience difficulties with activities of daily living (ADLs) due to impaired executive functioning, increasing sedentary behaviours. The HeyJoy Octopus watch, a child-friendly icon-based smartwatch could be used as an enabler to promote purposeful ADLs (i.e., goal-orientated ADLs). Objective: to investigate the effectiveness of the Octopus watch in promoting purposeful ADLs for children living with SB&/H (<8 years). Methods: Mixed-methods engaging parents and children in four phases: (1) Administered demographic questionnaire, semi-structured interview, childhood executive functioning inventory (CHEXI) and the Canadian occupational performance measure (COPM); focus group one introducing the study, information pack using smartwatch and photovoice data collection methods. (2) Measured baseline movement for four days with smartwatch without using functions. (3) Measured activity for 16-days while using the smartwatch. (4) Re-administered assessments and conducted a second focus group based on photovoice narratives. Results: movement data recorded for four participants, three of four showed mean activity increase (36%). N-of-1 analyses found one participant showed clear improvement (p = 0.021, r2 = 0.28). Mean inhibition decreased by 16.4%, and mean change in COPM performance and satisfaction scores were 2.1 and 2.4, respectively. The photovoice narrative focus group supports findings evidenced with improved daily routines. Conclusions: The Octopus watch is an innovative early intervention that can promote purposeful ADLs, fostering family resilience by enhancing occupational engagement. Further research is required.
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Wang, Jin-Gui, Ke-Long Cai, Zhi-Mei Liu, Fabian Herold, Liye Zou, Li-Na Zhu, Xuan Xiong, and Ai-Guo Chen. "Effects of Mini-Basketball Training Program on Executive Functions and Core Symptoms among Preschool Children with Autism Spectrum Disorders." Brain Sciences 10, no. 5 (April 30, 2020): 263. http://dx.doi.org/10.3390/brainsci10050263.

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This study examined the effects of a 12-week mini-basketball training program (MBTP) on executive functions and core symptoms among preschoolers with autism spectrum disorder (ASD). In this quasi-experimental pilot study, 33 ASD preschoolers who received their conventional rehabilitation program were assigned to either a MBTP group (n = 18) or control group (n = 15). Specifically, the experimental group was required to take an additional 12-week MBTP (five days per week, one session per day, and forty minutes per session), while the control group was instructed to maintain their daily activities. Executive functions and core symptoms (social communication impairment and repetitive behavior) were evaluated by the Childhood Executive Functioning Inventory (CHEXI), the Social Responsiveness Scale-Second Edition (SRS-2), and the Repetitive Behavior Scale-Revised (RBS-R), respectively. After the 12-week intervention period, the MBTP group exhibited significantly better performances in working memory (F = 7.51, p < 0.01, partial η2 = 0.195) and regulation (F = 4.23, p < 0.05, partial η2 = 0.12) as compared to the control group. Moreover, the MBTP significantly improved core symptoms of ASD preschoolers, including the social communication impairment (F = 6.02, p < 0.05, partial η2 = 0.020) and repetitive behavior (F = 5.79, p < 0.05, partial η2 = 0.016). Based on our findings, we concluded that the 12-week MBTP may improve executive functions and core symptoms in preschoolers with ASD, and we provide new evidence that regular physical exercise in the form of a MBTP is a promising alternative to treat ASD.
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Sijie, Han, Sang Shuxun, Zhou Peiming, Jia Jinlong, and Liang Jingjing. "Burial history and the evolution of hydrocarbon generation in Carboniferous-Permian coal measures within the Jiyang super-depression, China." Earth Sciences Research Journal 24, no. 4 (January 26, 2021): 397–408. http://dx.doi.org/10.15446/esrj.v24n4.63220.

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In the Jiyang Sub-basin, Carboniferous-Permian (C-P) coal-measure source rocks have experienced complex multi-stage tectonics and therefore have a complex history of hydrocarbon generation. Because these coal measures underwent multi-stage burial and exhumation, they are characterized by various burial depths. In this study, we used the basin modeling technique to analyze the relationship between burial history and hydrocarbon generation evolution. The burial, thermal and maturity histories of C-P coals were reconstructed, including primary hydrocarbon generation, stagnation, re-initiation, and peak secondary hydrocarbon generation. The secondary hydrocarbon generation stage within this reconstruction was characterized by discontinuous generation and geographical differences in maturity due to the coupled effects of depth and a delay of hydrocarbon generation. According to the maturity history and the delay effect on secondary hydrocarbon generation, we concluded that the threshold depth of secondary hydrocarbon generation in the Jiyang Sub-basin occurred at 2,100 m during the Yanshan epoch (from 205 Ma to 65 Ma) and at 3,200 m during the Himalayan period (from 65 Ma to present). Based on depth, residual thickness, maturity, and hydrocarbon-generating intensity, five favorable areas of secondary hydrocarbon generation in the Jiyang Sub-basin were identified, including the Chexi areas, Gubei-Luojia areas, Yangxin areas, the southern slope of the Huimin depression and southwest of the Dongying depression. The maximum VRo/burial depth (%/km) occurred in the Indosinian epoch as the maximum VRo/time (%/100Ma) happened in the Himalayan period, indicating that the coupling controls of temperature and subsidence rate on maturation evolution play a significant role in the hydrocarbon generation evolution. A higher temperature and subsidence rate can both enhance the hydrocarbon generation evolution.
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DAHANE, Ihsane. "EXECUTIVE FUNCTIONS IN EARLY CHILDHOOD: A MAJOR LEVER FOR THE HEALTHY AND BALANCED DEVELOPMENT OF PRESCHOOL CHILDREN." RIMAK International Journal of Humanities and Social Sciences 03, no. 03 (March 1, 2021): 198–208. http://dx.doi.org/10.47832/2717-8293.3-3.17.

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The early childhood is considered as one of the decisive stages in a child’s life. It’s viewed as the first building block that shapes the child’s personality in all its aspects, as this is when the child begins to deal with his external surrounding. Moreover, during this period the child's awareness grows towards autonomy. He starts to rely on himself in his actions and movement confidently. What the child experiences in his first years, shapes all his upcoming learnings. For instance, during the preschool, the child starts acquiring new principles and grasps some abstract concepts like solidarity, participation, socialization … The institution also works on promoting all the skills which are related to artistic creativity, recreational and educational activities. And since the intervention at this stage has a great impact on the child’s scholastic success, Its consequences positively affect the child’s health and behavior, as well as his cognitive and mental development. Thus, the recent studies have shed light on the child's cognitive development in early stages. And focused mainly on understanding and identifying the factors affecting this development. A reference should be made that the child's cognitive development is crucially related scholastic success. That’s to say, by promoting the executive functions (inhibition - cognitive flexibility – memory – planning and organizing…) at the very early childhood stage is regarded as the cornerstone for building a child’s cognitive skills and acquiring social behavior. This research study aims to explore the children’s executive functions state at their early childhood stage (preschool children) in order to identify the strengths and weaknesses which needs intervention. The study was implemented by using the CHILDHOOD EXECUTIVE FUNCTIONING INVENTORY (CHEXI) FOR PARENTS AND TEACHERS. The study participant were 150 children, divided among 10 educators in the second preparatory level at 4 different schools. The latter are part of (The Moroccan Foundation for the Promotion of preSchool education) in the Rabat region. It was concluded that the executive functions of preschool children still need further reinforcement and development by setting up an intervention program.
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Lopez-Astacio, Hiram J., Lisandro Cunci, and Christopher Pollock. "Development and Improvement of an Electrochemical Cell for X-Ray Fluorescence and Absorption Spectroscopy." ECS Meeting Abstracts MA2022-02, no. 60 (October 9, 2022): 2472. http://dx.doi.org/10.1149/ma2022-02602472mtgabs.

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The use of X-ray spectroscopy is an essential technique for the study of any material. Our research investigated the electrochemical cell design and improvement for X-ray absorption and fluorescence spectroscopy. Our objective was to improve the design capability of the current electrochemical cell design to perform absorption and fluorescence spectroscopy at once. By changing the geometry of the receiving window on the electrochemical cell, we could accomplish both fluorescence and absorption spectroscopy functions for CHEXS experiments. Our approach was a simple, inexpensive prototype cycle that anyone could use. Using a hobbyist Computer Numerical Control (CNC) and free 3D CAD software, anyone can develop a reliable electrochemical cell using our design. The electrochemical cell was fabricated using a small computer numerical control system, which allowed a fast turnaround for our project. Our work contributed to designing an open-source electrochemical cell that CHESS or any user could use, modify and share for future projects. Scientifically, we aimed to implement the ability to do both fluorescence and absorption spectroscopy, incorporate the ability to purge the cell with a gas, decrease ionic resistance in the cell to have all the electrodes within the same cell, and avoid leaks. The development of a new electrochemical cell design was made to improve the reliability and performance of the cell for CHESS experiments. By re-arranging the positions of the working electrode (WE), counter electrode (CE), and reference electrode (RE), we accomplished low ionic resistance within the cell. In addition, creating a 45-degree angle slope on both sides of the X-ray receiving window will allow the design of the electrochemical cell to perform fluorescence and absorption spectroscopy simultaneously. Furthermore, an add-on to the top of the electrochemical cell was designed to perform gas purging of the cell successfully. Lastly, the change from an o-ring to a gasket addressed the leakage problem thoroughly.
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Masood, Talha Bin, Sankaran Sandhya, Nagasuma Chandra, and Vijay Natarajan. "CHEXVIS: a tool for molecular channel extraction and visualization." BMC Bioinformatics 16, no. 1 (April 16, 2015). http://dx.doi.org/10.1186/s12859-015-0545-9.

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Yang, Heejung, Namgil Lee, Beomjun Park, Jinyoung Park, Jiho Lee, Hyeon Seok Jang, and Hojin Yoo. "Hierarchical network analysis of co-occurring bioentities in literature." Scientific Reports 12, no. 1 (May 12, 2022). http://dx.doi.org/10.1038/s41598-022-12093-9.

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AbstractBiomedical databases grow by more than a thousand new publications every day. The large volume of biomedical literature that is being published at an unprecedented rate hinders the discovery of relevant knowledge from keywords of interest to gather new insights and form hypotheses. A text-mining tool, PubTator, helps to automatically annotate bioentities, such as species, chemicals, genes, and diseases, from PubMed abstracts and full-text articles. However, the manual re-organization and analysis of bioentities is a non-trivial and highly time-consuming task. ChexMix was designed to extract the unique identifiers of bioentities from query results. Herein, ChexMix was used to construct a taxonomic tree with allied species among Korean native plants and to extract the medical subject headings unique identifier of the bioentities, which co-occurred with the keywords in the same literature. ChexMix discovered the allied species related to a keyword of interest and experimentally proved its usefulness for multi-species analysis.
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Černák, J., J. Chomič, C. Kappenstein, and M. Dunaj-Jurčo. "Crystal and molecular structure of two Zn–Cu compounds: Zn(NH3)2Cu(CN)3 and [Zn(en)3]6[Cu5(CN)17] · nH2O (n = 8.4) containing novel [Cu2(CN)7]5− ion." Zeitschrift für Kristallographie - Crystalline Materials 209, no. 5 (January 1, 1994). http://dx.doi.org/10.1524/zkri.1994.209.5.430.

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AbstractThe result of crystal structure analysis of two Zn–Cu bimetallic complexes are reported. Poly-[diammine-zinc(II)-tricyanocuprate(I)], CHexakis-[tris(ethylenediamine)-zinc(II)-tricyanocuprate bis[heptacyanodicuprate)-
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KARABEKMEZ, Sibel, and Berrin AKMAN. "Examination of the Executive Function Skills of 5-Year-Old Children Receiving Pre-School Education According to Some Variables." OPUS Journal of Society Research, July 4, 2022. http://dx.doi.org/10.26466/opusjsr.1112099.

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The aim of this study is to examine the executive function skills of 5-year-old children receiving pre-school education in terms of gender, duration of pre-school education, parental education and age status, maternal employment status, children's digital game playing status and digital game playing frequency variables. The study was carried out through the descriptive survey model, which is among the quantitative research methods, and the convenience sampling method, which is among the non-random sampling methods. The population of the study consists of 5-year-old children receiving pre-school education and the sample group consists of 332 children in the 5-year-old group who attend independent kindergartens affiliated to the Ministry of National Education in Ağrı and who are allowed by their parents to participate in the research. 'The Childhood Executive Function Inventory (CHEXI)-Teacher Form' and the Child Information Form prepared by the researchers were used within the context of the study. As a result of the study, no significant difference was found in CHEXI-Teacher Form scores in terms of the variables of duration of preschool education, parent education and age status, and maternal employment status. However, it was observed that CHEXI-Teacher Form scores were significantly higher for boys compared to girls, for children who play digital games compared to those who do not, and for children who play digital games more than once a day compared to children who play less frequently.
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Amukune, Stephen, Gabriella Józsa, and Krisztián Józsa. "Comparing Executive Functioning in the School Readiness of Hungarian and Kenyan Preschoolers." International Journal of Early Childhood, September 16, 2022. http://dx.doi.org/10.1007/s13158-022-00331-0.

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AbstractCross-national comparisons represent an avenue for investigating milestones achieved by one region that can help improve standards in another country. This study compares the development of executive functioning in Hungarian and Kenyan preschoolers as they prepare for school readiness. The study's cross-sectional design entailed sampling preschoolers from Hungary (n = 187) and Kenya (n = 420) aged between 4 and 8 years nested in 35 classrooms. Preschool class teachers rated the children's executive functioning using the Childhood Executive Functioning Inventory (CHEXI). The two-factor structure of the CHEXI demonstrated a strong measurement invariance for the two countries, Hungary and Kenya. Significant gender differences were noted on both subscales in the Hungarian sample but not in the Kenyan preschoolers. Additionally, no differences were found in the executive functioning of boys from both countries. However, the girls exhibited variances in the inhibition subscale. Contrary to expectations, no linear mixed effects were observed for country or the interactions between age and country apropos difficulties related to inhibition and total executive functioning except for working memory. Better working memory skills noted in the Hungarian sample were attributed to a superior preschool education system.
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GÖKTAŞ, Ayşe. "Executive Functions and Activity Participation of Children with Special Needs in the COVID-19 Pandemic Process." Ergoterapi ve Rehabilitasyon Dergisi, September 1, 2022. http://dx.doi.org/10.30720/ered.1038231.

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Purpose: The study was conducted to determine the participation of children with special needs in leisure time activities and the relationship between executive functions and activities during the pandemic process. Material and Methods: "Canadian Occupational Performance Measurement (COPM)" was used to measure children's participation in leisure activities and the "Childhood Executive Function Inventory Parent/Teacher Form (CHEXI)" to determine their level of executive functions. CHEXI consists of working memory and inhibitory control subheadings. Results: A total of 37 children, 20 girls and 17 boys, aged 2-20 years, with a mean age of 13.1±4.5 years, were included in the study. The mean working memory score was 46.18±7.06, and the inhibitory control score was 35.51±10.18. It was determined that there was a relationship between executive functions and activity types in children participating in activities (p&lt;0.05). There were significant correlations between inhibition and team sports (r=-0.360, p=0,029) and running (r=-0.334, p=0.043) in participation in physical activities. A significant correlation was found between working memory and music/painting/handicrafts (r=-0.400, p=0.014) in participation in skilled activities. Conclusion: Since the study results have shown that the executive functions of children participating in activities are positively affected during the pandemic, it is thought that activity-oriented programs will contribute significantly to the support of executive functions in the management of this process.
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Rajpurkar, Pranav, Chloe O’Connell, Amit Schechter, Nishit Asnani, Jason Li, Amirhossein Kiani, Robyn L. Ball, et al. "CheXaid: deep learning assistance for physician diagnosis of tuberculosis using chest x-rays in patients with HIV." npj Digital Medicine 3, no. 1 (September 9, 2020). http://dx.doi.org/10.1038/s41746-020-00322-2.

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Abstract Tuberculosis (TB) is the leading cause of preventable death in HIV-positive patients, and yet often remains undiagnosed and untreated. Chest x-ray is often used to assist in diagnosis, yet this presents additional challenges due to atypical radiographic presentation and radiologist shortages in regions where co-infection is most common. We developed a deep learning algorithm to diagnose TB using clinical information and chest x-ray images from 677 HIV-positive patients with suspected TB from two hospitals in South Africa. We then sought to determine whether the algorithm could assist clinicians in the diagnosis of TB in HIV-positive patients as a web-based diagnostic assistant. Use of the algorithm resulted in a modest but statistically significant improvement in clinician accuracy (p = 0.002), increasing the mean clinician accuracy from 0.60 (95% CI 0.57, 0.63) without assistance to 0.65 (95% CI 0.60, 0.70) with assistance. However, the accuracy of assisted clinicians was significantly lower (p < 0.001) than that of the stand-alone algorithm, which had an accuracy of 0.79 (95% CI 0.77, 0.82) on the same unseen test cases. These results suggest that deep learning assistance may improve clinician accuracy in TB diagnosis using chest x-rays, which would be valuable in settings with a high burden of HIV/TB co-infection. Moreover, the high accuracy of the stand-alone algorithm suggests a potential value particularly in settings with a scarcity of radiological expertise.
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Price, Anna, Hannah Bryson, Fiona K. Mensah, Bridget Kenny, Xiaofang Wang, Francesca Orsini, Lisa Gold, et al. "Embedding nurse home visiting in universal healthcare: 6-year follow-up of a randomised trial." Archives of Disease in Childhood, June 30, 2023, archdischild—2023–325662. http://dx.doi.org/10.1136/archdischild-2023-325662.

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ObjectiveNurse home visiting (NHV) is designed to redress child and maternal health inequities. Of the previous trials to investigate NHV benefits beyond preschool, none were designed for populations with universal healthcare. To address this evidence gap, we investigated whether the Australian ‘right@home’ NHV programme improved child and maternal outcomes when children turned 6 and started school.MethodsA screening survey identified pregnant women experiencing adversity from antenatal clinics across two states (Victoria, Tasmania). 722 were randomised: 363 to the right@home programme (25 visits promoting parenting and home learning environment) and 359 to usual care. Child measures at 6 years (first school year): Strengths and Difficulties Questionnaire (SDQ), Social Skills Improvement System (SSIS), Childhood Executive Functioning Inventory (CHEXI) (maternal/teacher-reported); general health and paediatric quality of life (maternal-reported) and reading/school adaptation items (teacher-reported). Maternal measures: Personal Well-being Index (PWI), Depression Anxiety Stress Scales, warm/hostile parenting, Child-Parent Relationship Scale (CPRS), emotional abuse and health/efficacy items. Following best-practice methods for managing missing data, outcomes were compared between groups (intention-to-treat) using regression models adjusted for stratification factors, baseline variables and clustering (nurse/site level).ResultsMothers reported on 338 (47%) children, and teachers on 327 (45%). Patterns of group differences favoured the programme arm, with small benefits (effect sizes ranging 0.15–0.26) evident for SDQ, SSIS, CHEXI, PWI, warm parenting and CPRS.ConclusionsFour years after completing the right@home programme, benefits were evident across home and school contexts. Embedding NHV in universal healthcare systems from pregnancy can offer long-term benefits for families experiencing adversity.Trial registration numberISRCTN89962120.
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Gutierrez, Marisel, Vanessa Arán Filippetti, and Viviana Lemos. "Executive functioning in pediatric acute lymphoblastic leukemia: CHEXI parent-report vs performance-based assessment." Current Psychology, February 24, 2021. http://dx.doi.org/10.1007/s12144-021-01524-x.

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Qassem Alyami, Ibrahim. "Psychometric analysis of Childhood Executive Functioning Inventory (CHEXI) in Saudi Arabian ADHD children: Calibration with Rasch model." Applied Neuropsychology: Child, May 4, 2023, 1–8. http://dx.doi.org/10.1080/21622965.2023.2208698.

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Dias, Natália Martins, and Alessandra Gotuzo Seabra. "The Promotion of Executive Functioning in a Brazilian Public School: A Pilot Study." Spanish Journal of Psychology 18 (2015). http://dx.doi.org/10.1017/sjp.2015.4.

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AbstractStudies have highlighted the role of early Executive Functioning (EF) interventions with regard to preventing behavioral and mental health problems. In this sense, interventions to promote EF have been developed and tested; however, in Latin America, evidence of early EF-related interventions is still limited. We developed a program for EF promotion in children and applied it to first-grade students. Sixty-eight six-year-old children and their five teachers were divided into an experimental group (EG) and a control group (CG). EG teachers administered the Intervention Program for Self-regulation and Executive Functions in a classroom context. The results of the ANCOVAs showed that children in the EG had significantly better performance in measures of cognitive flexibility (Trail Making Test for Preschoolers; p = .05), attention (Cancellation Attention Test – errors in the Part 3; p = .027), inhibition (Simon Task – interference score in the part 1; p = .008 and interference reaction time in the part 2; p = .010), and planning (CHEXI - planning scale; p = .041) than those in the CG. The results show that EF can be promoted using classroom intervention in public schools. These results expand previous findings for Latin America.
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Mashhadi, Ali, Zahra Hosseinzadeh Maleki, Jafar Hasani, Kazem Rasoolzadeh Tabatabaei, and Shirin Saleh. "Psychometric properties of the childhood executive functioning inventory (CHEXI): A confirmatory factor analysis and measurement invariance by sex and age in Iranian children." Neuropsychological Rehabilitation, January 6, 2022, 1–19. http://dx.doi.org/10.1080/09602011.2021.2021952.

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