Relevant bibliographies by topics / Chemoselective glycosylation

Academic literature on the topic 'Chemoselective glycosylation'

Author: Grafiati
Published: 9 March 2023
Last updated: 10 March 2023

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Journal articles on the topic "Chemoselective glycosylation"

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Nguyen, Hien M., Jennifer L. Poole, and David Y. Gin. "Chemoselective Iterative Dehydrative Glycosylation." Angewandte Chemie 113, no. 2 (January 19, 2001): 428–31. http://dx.doi.org/10.1002/1521-3757(20010119)113:2<428::aid-ange428>3.0.co;2-b.

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Nguyen, Hien M., Jennifer L. Poole, and David Y. Gin. "Chemoselective Iterative Dehydrative Glycosylation." Angewandte Chemie International Edition 40, no. 2 (January 19, 2001): 414–17. http://dx.doi.org/10.1002/1521-3773(20010119)40:2<414::aid-anie414>3.0.co;2-6.

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Yang, Weizhun, Bo Yang, Sherif Ramadan, and Xuefei Huang. "Preactivation-based chemoselective glycosylations: A powerful strategy for oligosaccharide assembly." Beilstein Journal of Organic Chemistry 13 (October 9, 2017): 2094–114. http://dx.doi.org/10.3762/bjoc.13.207.

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Most glycosylation reactions are performed by mixing the glycosyl donor and acceptor together followed by the addition of a promoter. While many oligosaccharides have been synthesized successfully using this premixed strategy, extensive protective group manipulation and aglycon adjustment often need to be performed on oligosaccharide intermediates, which lower the overall synthetic efficiency. Preactivation-based glycosylation refers to strategies where the glycosyl donor is activated by a promoter in the absence of an acceptor. The subsequent acceptor addition then leads to the formation of the glycoside product. As donor activation and glycosylation are carried out in two distinct steps, unique chemoselectivities can be obtained. Successful glycosylation can be performed independent of anomeric reactivities of the building blocks. In addition, one-pot protocols have been developed that have enabled multiple-step glycosylations in the same reaction flask without the need for intermediate purification. Complex glycans containing both 1,2-cis and 1,2-trans linkages, branched oligosaccharides, uronic acids, sialic acids, modifications such as sulfate esters and deoxy glycosides have been successfully synthesized. The preactivation-based chemoselective glycosylation is a powerful strategy for oligosaccharide assembly complementing the more traditional premixed method.
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Figuereido, Ines, Alice Paiotta, Roberta Dal Magro, Francesca Tinelli, Roberta Corti, Francesca Re, Valeria Cassina, Enrico Caneva, Francesco Nicotra, and Laura Russo. "A New Approach for Glyco-Functionalization of Collagen-Based Biomaterials." International Journal of Molecular Sciences 20, no. 7 (April 9, 2019): 1747. http://dx.doi.org/10.3390/ijms20071747.

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The cell microenvironment plays a pivotal role in mediating cell adhesion, survival, and proliferation in physiological and pathological states. The relevance of extracellular matrix (ECM) proteins in cell fate control is an important issue to take into consideration for both tissue engineering and cell biology studies. The glycosylation of ECM proteins remains, however, largely unexplored. In order to investigate the physio-pathological effects of differential ECM glycosylation, the design of affordable chemoselective methods for ECM components glycosylation is desirable. We will describe a new chemoselective glycosylation approach exploitable in aqueous media and on non-protected substrates, allowing rapid access to glyco-functionalized biomaterials.
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Xiao, Ke, Yongxin Hu, Yongyong Wan, XinXin Li, Qin Nie, Hao Yan, Liming Wang, et al. "Hydrogen bond activated glycosylation under mild conditions." Chemical Science 13, no. 6 (2022): 1600–1607. http://dx.doi.org/10.1039/d1sc05772c.

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A mild glycosylation system was developed using glycosyl imidate donors and a charge-enhanced thiourea H-bond donor catalyst. The method can be used for the effective synthesis of O-, C-, S- and N-glycosides and chemoselective one-pot glycosylation.
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Nguyen, Hien M., Jennifer L. Poole, and David Y. Gin. "ChemInform Abstract: Chemoselective Iterative Dehydrative Glycosylation." ChemInform 32, no. 21 (May 26, 2010): no. http://dx.doi.org/10.1002/chin.200121063.

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Calce, Enrica, Giuseppe Digilio, Valeria Menchise, Michele Saviano, and Stefania De Luca. "Chemoselective Glycosylation of Peptides through S-Alkylation Reaction." Chemistry - A European Journal 24, no. 23 (April 14, 2018): 6231–38. http://dx.doi.org/10.1002/chem.201800265.

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Langenhan, Joseph M., Edouard Mullarky, Derek K. Rogalsky, James R. Rohlfing, Anja E. Tjaden, Halina M. Werner, Leonardo M. Rozal, and Steven A. Loskot. "Amphimedosides A–C: Synthesis, Chemoselective Glycosylation, And Biological Evaluation." Journal of Organic Chemistry 78, no. 4 (February 7, 2013): 1670–76. http://dx.doi.org/10.1021/jo302640y.

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Yang, You, Yao Li, and Biao Yu. "Chemoselective glycosylation of carboxylic acid with glycosyl ortho-hexynylbenzoates as donors." Tetrahedron Letters 51, no. 11 (March 2010): 1504–7. http://dx.doi.org/10.1016/j.tetlet.2010.01.039.

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Chiba, Hiroyuki, Setsuo Funasaka, Koichi Kiyota, and Teruaki Mukaiyama. "Catalytic and Chemoselective Glycosylation between “Armed” and “Disarmed” Glycosylp-Trifluoromethylbenzylthio-p-trifluoromethylphenyl Formimidates." Chemistry Letters 31, no. 7 (July 2002): 746–47. http://dx.doi.org/10.1246/cl.2002.746.

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Dissertations / Theses on the topic "Chemoselective glycosylation"

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PALMIOLI, ALESSANDRO. "Synthesis and biological characterization of new molecules pharnacologically active derived from natural compouds." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2009. http://hdl.handle.net/10281/7461.

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The inhibition of the oncogenic variants of Ras proteins represents an interesting and promising research field for the development of new anticancer therapies. During this thesis several important data were collected in order to clarify the structure activity relationship in Ras-inhibitors. Then new lead compounds derived from natural carbohydrates were designed and synthesized following a rational drug design approach. These original water-soluble molecules were investigated for the biological activity point of view; in addition the binding to human Ras was fully investigated, identifying the ligand-Ras binding interface.
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Perkins, Philip Raymond. "Novel thioglycosides towards chemoselective glycosylations." Thesis, University of Bath, 2003. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425864.

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Guo, Jhe-Ruei, and 郭哲睿. "Studies on the Total Synthesis of Neuritogenic Active Ganglioside SJG-1 by Chemoselective Glycosylation Strategy." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/12445700780636565829.

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碩士
中原大學
化學研究所
100
The nature product SJG-1 showed the nerve-growth activity, which wad isolatedfrom the sea cucumber S. japonicus. Owing to the biological activity, prompted us to study the total synthesis of these compound. The purpose of this thesis is its chemoselective glycosylation reaction to the rapid synthesis of the target and to shorten the synthetic steps. Up the rapid synthesis of the purpose of this thesis, reference Demchenko strategy for the synthesis of sialic acid glycosides of Neu-4, the introduction of PhS-leaving group; the building unit Glc-6 in the glucose-STaz leaving group. Sugar donor sialic acid Neu-4 with the sugar receptor glucose Glc-6 by glycosylation reaction yield of 62% mixture of disaccharide NG-1, it’s a : b of 3.0: 1.0. disaccharide NG-1 and ceramide amine derivatives Lyx-8 works the glycosylation reaction, get the NGL-1, yield 40%. NGL-1 through a few steps of the reaction, can be successfully synthesized the target SJG-1.
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Books on the topic "Chemoselective glycosylation"

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Kärkkäinen, Tiina Sinikka. Studies on chemoselective glycosylations: Exploiting electron withdrawing leaving groups. Birmingham: University of Birmingham, 1996.

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2

Guertsen, Richard Alexander. Different sized anomeric thio-leaving groups in chemoselective glycosylations. Birmingham: University of Birmingham, 1998.

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Book chapters on the topic "Chemoselective glycosylation"

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Aich, Udayanath, and Kevin J. Yarema. "Non-Natural Sugar Analogues: Chemical Probes for Metabolic Oligosaccharide Engineering Metabolic engineering Non-natural sugar Glycosylation pathways Mucins O-GlcNAc protein modification Chemoselective ligation." In Glycoscience, 2133–90. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-30429-6_55.

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"Synthesis of Oligosaccharides by Preactivation-Based Chemoselective Glycosylation of Thioglycosyl Donors." In Carbohydrate Chemistry, 75–84. CRC Press, 2016. http://dx.doi.org/10.1201/b11261-10.

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Peri, Francesco. "Chemoselective Glycosylation Techniques for the Synthesis of Bioactive Neoglycoconjugates, Glyconanoparticles and Glycoarrays." In Synthesis and Biological Applications of Glycoconjugates, 203–25. BENTHAM SCIENCE PUBLISHERS, 2012. http://dx.doi.org/10.2174/978160805277611101010203.

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You might also be interested in the extended bibliographies on the topic 'Chemoselective glycosylation' for particular source types:
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