Journal articles on the topic 'Chemical profiling'

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1

Piotrowski, Jeff S., Chuek Hei Ho, and Charles Boone. "The Awesome Power of Synergy from Chemical-Chemical Profiling." Chemistry & Biology 17, no. 8 (August 2010): 789–90. http://dx.doi.org/10.1016/j.chembiol.2010.08.002.

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2

Imran, Ali, Masood Sadiq Butt, Mian Kamran Sha, and Javed Iqbal Sult. "Chemical Profiling of Black Tea Polyphenols." Pakistan Journal of Nutrition 12, no. 3 (February 15, 2013): 261–67. http://dx.doi.org/10.3923/pjn.2013.261.267.

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3

Lewis, Melissa M., Yi Yang, Ewa Wasilewski, Hance A. Clarke, and Lakshmi P. Kotra. "Chemical Profiling of Medical Cannabis Extracts." ACS Omega 2, no. 9 (September 22, 2017): 6091–103. http://dx.doi.org/10.1021/acsomega.7b00996.

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4

Mazák, Károly, Sándor Hosztafi, Márta Kraszni, and Béla Noszál. "Physico-chemical profiling of semisynthetic opioids." Journal of Pharmaceutical and Biomedical Analysis 135 (February 2017): 97–105. http://dx.doi.org/10.1016/j.jpba.2016.12.014.

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5

Horning, Benjamin D., Radu M. Suciu, Darian A. Ghadiri, Olesya A. Ulanovskaya, Megan L. Matthews, Kenneth M. Lum, Keriann M. Backus, Steven J. Brown, Hugh Rosen, and Benjamin F. Cravatt. "Chemical Proteomic Profiling of Human Methyltransferases." Journal of the American Chemical Society 138, no. 40 (September 30, 2016): 13335–43. http://dx.doi.org/10.1021/jacs.6b07830.

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6

Martin, Brent R. "Chemical approaches for profiling dynamic palmitoylation." Biochemical Society Transactions 41, no. 1 (January 29, 2013): 43–49. http://dx.doi.org/10.1042/bst20120271.

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Protein palmitoylation is a critical post-translational modification important for membrane compartmentalization, trafficking and regulation of many key signalling proteins. Recent non-radioactive chemo-proteomic labelling methods have enabled a new focus on this emerging regulatory modification. Palmitoylated proteins can now be profiled in complex biological systems by MS for direct annotation and quantification. Based on these analyses, palmitoylation is clearly widespread and broadly influences the function of many cellular pathways. The recent introduction of selective chemical labelling approaches has opened new opportunities to revisit long-held questions about the enzymatic regulation of this widespread post-translational modification. In the present review, we discuss the impact of new chemical labelling approaches and future challenges for the dynamic global analysis of protein palmitoylation.
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7

THORNTON, JOHN I. "DNA Profiling." Chemical & Engineering News 67, no. 47 (November 20, 1989): 18–30. http://dx.doi.org/10.1021/cen-v067n047.p018.

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8

Badea, Georgiana Ileana, Ioana Diaconu, and Gabriel Lucian Radu. "Organic Acids Chemical Profiling in Food Items." Revista de Chimie 68, no. 6 (July 15, 2017): 1147–52. http://dx.doi.org/10.37358/rc.17.6.5631.

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A fast separation method for simultaneous determination of eleven organic acids was validated and applied to different commercial food items to evaluate their organic acids content. The present method gives detection limits between 0.04 and 4.65 mg mL-1, recovery values in real samples between 78.2 and 97.3% and relative standard deviation values for precision lower than 5%. All validation data were in acceptable range and prove the method�s fit for purpose. The advantages of the method are the short runtime analysis (15 min), no preparation step for the samples before the injection combined with good sensitivity which recommends it for routine control analysis in food industries. Moreover, this methodology has high potential in drinks industry but can by further extended to other types of food items.
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9

Lagurin, L. G., M. O. Galingana, J. D. J. Magsalin, J. E. S. Escaño, and F. M. Dayrit. "Chemical profiling of Philippine Moringa oleifera leaves." Acta Horticulturae, no. 1158 (April 2017): 257–68. http://dx.doi.org/10.17660/actahortic.2017.1158.29.

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10

Imran, Muhammad, Masood Sadiq Butt, Faqir Muhammad Anjum, and Javed Iqbal Sultan. "Chemical Profiling of Different Mango Peel Varieties." Pakistan Journal of Nutrition 12, no. 10 (September 15, 2013): 934–42. http://dx.doi.org/10.3923/pjn.2013.934.942.

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11

Wong, Jason W. H., James P. McRedmond, and Gerard Cagney. "Activity profiling of platelets by chemical proteomics." PROTEOMICS 9, no. 1 (January 2009): 40–50. http://dx.doi.org/10.1002/pmic.200800185.

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12

Tskhovrebov, Alexander G., Julia B. Lingnau, and Alois Fürstner. "Gold Difluorocarbenoid Complexes: Spectroscopic and Chemical Profiling." Angewandte Chemie International Edition 58, no. 26 (June 24, 2019): 8834–38. http://dx.doi.org/10.1002/anie.201903957.

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13

Tskhovrebov, Alexander G., Julia B. Lingnau, and Alois Fürstner. "Gold Difluorocarbenoid Complexes: Spectroscopic and Chemical Profiling." Angewandte Chemie 131, no. 26 (May 16, 2019): 8926–30. http://dx.doi.org/10.1002/ange.201903957.

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14

Vasquez, R. P., M. C. Foote, and B. D. Hunt. "Nonaqueous chemical depth profiling of YBa2Cu3O7−x." Applied Physics Letters 54, no. 11 (March 13, 1989): 1060–62. http://dx.doi.org/10.1063/1.101425.

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15

Ouarhach, A., J. Costa, and A. Romane. "Chemical Profiling of Lavandula maroccana of Morocco." Chemistry of Natural Compounds 56, no. 2 (March 2020): 348–50. http://dx.doi.org/10.1007/s10600-020-03028-9.

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16

Griswold, Andrew R., Paolo Cifani, Sahana D. Rao, Abram J. Axelrod, Matthew M. Miele, Ronald C. Hendrickson, Alex Kentsis, and Daniel A. Bachovchin. "A Chemical Strategy for Protease Substrate Profiling." Cell Chemical Biology 26, no. 6 (June 2019): 901–7. http://dx.doi.org/10.1016/j.chembiol.2019.03.007.

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17

van Helmond, Ward, Annemijn W. van Herwijnen, Joëlle J. H. van Riemsdijk, Marc A. van Bochove, Christianne J. de Poot, and Marcel de Puit. "Chemical profiling of fingerprints using mass spectrometry." Forensic Chemistry 16 (December 2019): 100183. http://dx.doi.org/10.1016/j.forc.2019.100183.

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18

Haubrich, Brad. "Microbial Sterolomics as a Chemical Biology Tool." Molecules 23, no. 11 (October 25, 2018): 2768. http://dx.doi.org/10.3390/molecules23112768.

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Metabolomics has become a powerful tool in chemical biology. Profiling the human sterolome has resulted in the discovery of noncanonical sterols, including oxysterols and meiosis-activating sterols. They are important to immune responses and development, and have been reviewed extensively. The triterpenoid metabolite fusidic acid has developed clinical relevance, and many steroidal metabolites from microbial sources possess varying bioactivities. Beyond the prospect of pharmacognostical agents, the profiling of minor metabolites can provide insight into an organism’s biosynthesis and phylogeny, as well as inform drug discovery about infectious diseases. This review aims to highlight recent discoveries from detailed sterolomic profiling in microorganisms and their phylogenic and pharmacological implications.
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19

Hu, Yechen, Zhongcheng Wang, Liang Liu, Jianhua Zhu, Dongxue Zhang, Mengying Xu, Yuanyuan Zhang, Feifei Xu, and Yun Chen. "Mass spectrometry-based chemical mapping and profiling toward molecular understanding of diseases in precision medicine." Chemical Science 12, no. 23 (2021): 7993–8009. http://dx.doi.org/10.1039/d1sc00271f.

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An overview of MS-based chemical mapping and profiling, indicating its contributions to the molecular understanding of diseases in precision medicine by answering "what", "where", "how many" and "whose” chemicals underlying clinical phenotypes.
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20

Huang, Ruili, Menghang Xia, Ming-Hsuang Cho, Srilatha Sakamuru, Paul Shinn, Keith A. Houck, David J. Dix, et al. "Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors." Environmental Health Perspectives 119, no. 8 (August 2011): 1142–48. http://dx.doi.org/10.1289/ehp.1002952.

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21

Lolita, G. Lagurin, Daniel J. Magsalin John, R. Zosa Anthony, and M. Dayrit Fabian. "Chemical profiling and chemical standardization of Vitex negundo using 13C NMR." Journal of Medicinal Plants Research 11, no. 1 (January 3, 2017): 11–21. http://dx.doi.org/10.5897/jmpr2015.6298.

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22

Xie, Zhuoer, Christina R. Ferreira, Alessandra A. Virequ, and R. Graham Cooks. "Multiple reaction monitoring profiling (MRM profiling): Small molecule exploratory analysis guided by chemical functionality." Chemistry and Physics of Lipids 235 (March 2021): 105048. http://dx.doi.org/10.1016/j.chemphyslip.2021.105048.

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23

Fernandes-Silva, Caroline C., Antonio Salatino, Maria Luiza F. Salatino, Ernesto D. H. Breyer, and Giuseppina Negri. "Chemical profiling of six samples of Brazilian propolis." Química Nova 36, no. 2 (2013): 237–40. http://dx.doi.org/10.1590/s0100-40422013000200006.

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24

Alves, C. A., M. Evtyugina, A. M. P. Vicente, E. D. Vicente, T. V. Nunes, P. M. A. Silva, M. A. C. Duarte, C. A. Pio, F. Amato, and X. Querol. "Chemical profiling of PM10 from urban road dust." Science of The Total Environment 634 (September 2018): 41–51. http://dx.doi.org/10.1016/j.scitotenv.2018.03.338.

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25

Ruprecht, Benjamin, Jana Zecha, Stephanie Heinzlmeir, Guillaume Médard, Simone Lemeer, and Bernhard Kuster. "Evaluation of Kinase Activity Profiling Using Chemical Proteomics." ACS Chemical Biology 10, no. 12 (October 5, 2015): 2743–52. http://dx.doi.org/10.1021/acschembio.5b00616.

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26

Dong, Xuejiao, Linfeng Gao, Jikui Song, and Yinsheng Wang. "Chemical Proteomic Profiling of Lysophosphatidic Acid-Binding Proteins." Analytical Chemistry 91, no. 24 (November 25, 2019): 15365–69. http://dx.doi.org/10.1021/acs.analchem.9b04850.

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27

Морозов (Morozov), Сергей (Sergey) Владимирович (Vladimirovich), Наталья (Natal'ya) Ивановна (Ivanovna) Ткачева (Tkacheva), and Алексей (Aleksej) Васильевич (Vasil'evich) Ткачев (Tkachev). "PROBLEMS OF COMPREHENSIVE CHEMICAL PROFILING OF MEDICINAL PLANTS." chemistry of plant raw material, no. 4 (December 11, 2018): 5–28. http://dx.doi.org/10.14258/jcprm.2018044003.

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Interest and attention to phytotherapy in Russia are increasing every year, which is consistent with global trends. Ensuring the growing demand inevitably leads to the appearance of phytopreparations of low quality and efficiency, and sometimes to a complete falsification of plant raw materials and preparations from it. Therefore, the pharmaceutical safety and quality of plant raw materials, herbal preparations and medicines from plant raw materials are among the most important problems in the field of medicine, biomedicine, pharmacognosy and phytochemistry. The review considers modern methodological approaches to solving problems of the problems mentioned, various concepts of identification, evaluation of the authenticity and quality control of herbal medicines using markers of various types and instrumental methods of chromatographic profiling (one of the methods of metabolic research) of plant compositions, spectral and hyphenated methods used to solve these problems, the issues of standardization of plant raw materials, drugs in and medicines based on it, the world experience in solving problems of assessing the quality of plant raw materials and phytopreparations and the state of research in Russia.
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28

Vieira, Roberto F., Renée J. Grayer, and Alan J. Paton. "Chemical profiling of Ocimum americanum using external flavonoids." Phytochemistry 63, no. 5 (July 2003): 555–67. http://dx.doi.org/10.1016/s0031-9422(03)00143-2.

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29

Rix, Uwe, and Giulio Superti-Furga. "Target profiling of small molecules by chemical proteomics." Nature Chemical Biology 5, no. 9 (September 18, 2008): 616–24. http://dx.doi.org/10.1038/nchembio.216.

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30

Kim, HJ, WS Park, JY Bae, JH Park, and MJ Ahn. "Anatomical characterization and chemical profiling of Rumex species." Planta Medica 81, S 01 (December 14, 2016): S1—S381. http://dx.doi.org/10.1055/s-0036-1596766.

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31

Evaristo, Isabel, Dora Batista, Isabel Correia, Paula Correia, and Rita Costa. "Chemical profiling of Portuguese Pinus pinea L. nuts." Journal of the Science of Food and Agriculture 90, no. 6 (March 9, 2010): 1041–49. http://dx.doi.org/10.1002/jsfa.3914.

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32

Nina, Nélida, Cristina Quispe, Felipe Jiménez-Aspee, Cristina Theoduloz, Alberto Giménez, and Guillermo Schmeda-Hirschmann. "Chemical profiling and antioxidant activity of Bolivian propolis." Journal of the Science of Food and Agriculture 96, no. 6 (July 29, 2015): 2142–53. http://dx.doi.org/10.1002/jsfa.7330.

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33

Médard, Guillaume, Fiona Pachl, Benjamin Ruprecht, Susan Klaeger, Stephanie Heinzlmeir, Dominic Helm, Huichao Qiao, et al. "Optimized Chemical Proteomics Assay for Kinase Inhibitor Profiling." Journal of Proteome Research 14, no. 3 (February 20, 2015): 1574–86. http://dx.doi.org/10.1021/pr5012608.

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34

Riordan, Colleen M., Kevin T. Jacobs, Pierre Negri, and Zachary D. Schultz. "Sheath flow SERS for chemical profiling in urine." Faraday Discussions 187 (2016): 473–84. http://dx.doi.org/10.1039/c5fd00155b.

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The molecular specificity and sensitivity of surface enhanced Raman scattering (SERS) makes it an attractive method for biomedical diagnostics. Here we present results demonstrating the utility and complications for SERS characterization in urine. The chemical fingerprint characteristics of Raman spectra suggest its use as a label free diagnostic; however, the complex composition of biological fluids presents a tremendous challenge. In particular, the limited number of surface sites and competing absorption tend to mask the presence of analytes in solution, particularly when the solution contains multiple analytes. To address these problems and characterize biological fluids we have demonstrated a sheath-flow interface for SERS detection. This sheath-flow SERS interface uses hydrodynamic focusing to confine analyte molecules eluting out of a column onto a planar SERS substrate where the molecules are detected by their intrinsic SERS signal. In this report we compare the direct detection of benzoylecgonine in urine using DSERS with chemical profiling by capillary zone electrophoresis and sheath-flow SERS detection. The SERS spectrum from the observed migration peaks can identify benzoylecgonine and other distinct spectra are also observed, suggesting improved chemical diagnostics in urine. With over 2000 reported compounds in urine, identification of each of the detected species is an enormous task. Nonetheless, these samples provide a benchmark to establish the potential clinical utility of sheath-flow SERS detection.
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35

Punzalan, Louvy Lynn, Lulu Jiang, Di Mao, Amarjyoti Das Mahapatra, Shinichi Sato, Yasushi Takemoto, Mari Tsujimura, et al. "Chemoproteomic Profiling of a Pharmacophore-Focused Chemical Library." Cell Chemical Biology 27, no. 6 (June 2020): 708–18. http://dx.doi.org/10.1016/j.chembiol.2020.04.007.

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36

Shiraiwa, Kazuki, Rong Cheng, Hiroshi Nonaka, Tomonori Tamura, and Itaru Hamachi. "Chemical Tools for Endogenous Protein Labeling and Profiling." Cell Chemical Biology 27, no. 8 (August 2020): 970–85. http://dx.doi.org/10.1016/j.chembiol.2020.06.016.

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37

Saito, Kosuke, Masaki Ishikawa, Hiroshi Yamada, Noriyuki Nakatsu, Keiko Maekawa, and Yoshiro Saito. "Plasma lipid profiling of chemical-induced liver injuries." Drug Metabolism and Pharmacokinetics 32, no. 1 (January 2017): S33. http://dx.doi.org/10.1016/j.dmpk.2016.10.145.

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38

Wakefield, Joshua, Kiri McComb, Emad Ehtesham, Robert Van Hale, David Barr, Jurian Hoogewerff, and Russell Frew. "Chemical profiling of saffron for authentication of origin." Food Control 106 (December 2019): 106699. http://dx.doi.org/10.1016/j.foodcont.2019.06.025.

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39

Šileikytė, Justina, Sunil Sundalam, Larry L. David, and Michael S. Cohen. "Chemical Proteomics Approach for Profiling the NAD Interactome." Journal of the American Chemical Society 143, no. 18 (April 29, 2021): 6787–91. http://dx.doi.org/10.1021/jacs.1c01302.

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40

Song, Jiabao, and Y. George Zheng. "Bioorthogonal Reporters for Detecting and Profiling Protein Acetylation and Acylation." SLAS DISCOVERY: Advancing the Science of Drug Discovery 25, no. 2 (November 11, 2019): 148–62. http://dx.doi.org/10.1177/2472555219887144.

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Protein acylation, exemplified by lysine acetylation, is a type of indispensable and widespread protein posttranslational modification in eukaryotes. Functional annotation of various lysine acetyltransferases (KATs) is critical to understanding their regulatory roles in abundant biological processes. Traditional radiometric and immunosorbent assays have found broad use in KAT study but have intrinsic limitations. Designing acyl–coenzyme A (CoA) reporter molecules bearing chemoselective chemical warhead groups as surrogates of the native cofactor acetyl-CoA for bioorthogonal labeling of KAT substrates has come into a technical innovation in recent years. This chemical biology platform equips molecular biologists with empowering tools in acyltransferase activity detection and substrate profiling. In the bioorthogonal labeling, protein substrates are first enzymatically modified with a functionalized acyl group. Subsequently, the chemical warhead on the acyl chain conjugates with either an imaging chromophore or an affinity handle or any other appropriate probes through an orthogonal chemical ligation. This bioorganic strategy reformats the chemically inert acetylation and acylation marks into a chemically maneuverable functionality and generates measurable signals without recourse to radioisotopes or antibodies. It offers ample opportunities for facile sensitive detection of KAT activity with temporal and spatial resolutions as well as allows for chemoproteomic profiling of protein acetylation pertaining to specific KATs of interest on the global scale. We reviewed here the past and current advances in bioorthogonal protein acylations and highlighted their wide-spectrum applications. We also discussed the design of other related acyl-CoA and CoA-based chemical probes and their deployment in illuminating protein acetylation and acylation biology.
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41

Ravi, Ramasamy, Ali Taheri, Durga Khandekar, and Reneth Millas. "Rapid Profiling of Soybean Aromatic Compounds Using Electronic Nose." Biosensors 9, no. 2 (May 24, 2019): 66. http://dx.doi.org/10.3390/bios9020066.

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Soybean (Glycine max (L.)) is the world’s most important seed legume, which contributes to 25% of global edible oil, and about two-thirds of the world’s protein concentrate for livestock feeding. One of the factors that limit soybean’s utilization as a major source of protein for humans is its characteristic soy flavor. This off-flavor can be attributed to the presence of various chemicals such as phenols, aldehydes, ketones, furans, alcohols, and amines. In addition, these flavor compounds interact with protein and cause the formation of new off-flavors. Hence, studying the chemical profile of soybean seeds is an important step in understanding how different chemical classes interact and contribute to the overall flavor profile of the crop. In our study, we utilized the HERCALES Fast Gas Chromatography (GC) electronic nose for identification and characterization of different volatile compounds in five high-yielding soybean varieties, and studied their association with off-flavors. With aroma profiling and chemical characterization, we aim to determine the quantity and quality of volatile compounds in these soybean varieties and understand their effect on the flavor profiles. The study could help to understand soybean flavor characteristics, which in turn could increase soybean use and enhance profitability.
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42

Tesche, Matthias, Boyan Tatarov, Youngmin Noh, and Detlef Müller. "Lidar sprectroscopy instrument (LISSI): An infrastructure facility for chemical aerosol profiling at the University of Hertfordshire." EPJ Web of Conferences 176 (2018): 01008. http://dx.doi.org/10.1051/epjconf/201817601008.

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The lidar development at the University of Hertfordshire explores the feasibility of using Raman backscattering for chemical aerosol profiling. This paper provides an overview of the new facility. A high-power Nd:YAG/OPO setup is used to excite Raman backscattering at a wide range of wavelengths. The receiver combines a spectrometer with a 32-channel detector or an ICCD camera to resolve Raman signals of various chemical compounds. The new facility will open new avenues for chemical profiling of aerosol pollution from measurements of Raman scattering by selected chemical compounds, provide data that allow to close the gap between optical and microphysical aerosol profiling with lidar and enables connecting lidar measurements to parameters used in atmospheric modelling.
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43

Bâldea, Ioan. "Profiling C4N radicals of astrophysical interest." Monthly Notices of the Royal Astronomical Society 493, no. 2 (February 14, 2020): 2506–10. http://dx.doi.org/10.1093/mnras/staa455.

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ABSTRACT Based on a theoretical study of neutral, anion, and cation $\text{C}_{4}\text{N}$ chains, we suggest that this molecular species can still be observed in space. We analyse the dependence on n of the enthalpies of formation across the $\text{C}_{{{ n}}}\text{N}$ family and present possible chemical pathways of $\text{C}_{4}\text{N}$ production, which are not only exoenergetic but also barrierless. To further assist astronomical observation, we report estimates obtained at the CCSD(T) level of theory for astrophysically and astrochemically relevant properties. These include structural and chemical data, dipole moments, vibrational frequencies, rotational and centrifugal distortion constants as well as electron affinity, ionization potential, and related chemical reactivity indices. Our results indicate that anion chains can be easily detected in space than neutral chains; $\text{C}_{4}\text{N}^{-}$ possesses a smaller enthalpy of formation and a substantially larger dipole moment than $\text{C}_{4}\text{N}^{\text{0}}$.
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44

Moore, J. C., J. G. Paren, and R. Mulvaney. "Chemical Evidence in Polar Ice Cores from Dielectric Profiling." Annals of Glaciology 14 (1990): 195–98. http://dx.doi.org/10.1017/s0260305500008569.

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The dielectric stratigraphy of a 130 m ice core from Dolleman Island, Antarctic Peninsula, shows large variations in the dielectric relaxation process and in conductivity. A comparison with the chemical stratigraphy of the core demonstrates the decisive role played by both acids and salts in determining the electrical behaviour of natural ice. The dielectric response is sensitive both to the type of impurity and to its distribution within the ice fabric. The evidence supports other observations of the localization of sulphuric acid at three-grain boundaries: in contrast, the salt impurity appears to be largely incorporated into the ice lattice. The overriding importance of the dielectric profiling technique is that it is the only profiling tool so far developed that is sensitive to the presence of salt in polar ice cores.
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45

Moore, J. C., J. G. Paren, and R. Mulvaney. "Chemical Evidence in Polar Ice Cores from Dielectric Profiling." Annals of Glaciology 14 (1990): 195–98. http://dx.doi.org/10.3189/s0260305500008569.

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The dielectric stratigraphy of a 130 m ice core from Dolleman Island, Antarctic Peninsula, shows large variations in the dielectric relaxation process and in conductivity. A comparison with the chemical stratigraphy of the core demonstrates the decisive role played by both acids and salts in determining the electrical behaviour of natural ice. The dielectric response is sensitive both to the type of impurity and to its distribution within the ice fabric. The evidence supports other observations of the localization of sulphuric acid at three-grain boundaries: in contrast, the salt impurity appears to be largely incorporated into the ice lattice. The overriding importance of the dielectric profiling technique is that it is the only profiling tool so far developed that is sensitive to the presence of salt in polar ice cores.
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46

Marsilani, O. N., Wagiman, and A. C. Sukartiko. "Chemical profiling of western Indonesian single origin robusta coffee." IOP Conference Series: Earth and Environmental Science 425 (February 8, 2020): 012041. http://dx.doi.org/10.1088/1755-1315/425/1/012041.

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47

Tihanyi, Karoly, Bela Noszal, Krisztina Takacs-Novak, and Katalin Deak. "Physico-Chemical Profiling of Antidepressive Sertraline: Solubility,Ionisation, Lipophilicity." Medicinal Chemistry 2, no. 4 (July 1, 2006): 385–89. http://dx.doi.org/10.2174/157340606777723997.

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48

Huang, Fuqiang, Boya Zhang, Shengtao Zhou, Xia Zhao, Ce Bian, and Yuquan Wei. "Chemical proteomics: terra incognita for novel drug target profiling." Chinese Journal of Cancer 31, no. 11 (November 5, 2012): 507–18. http://dx.doi.org/10.5732/cjc.011.10377.

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49

Heal, William, Sasala Wickramasinghe, and Edward Tate. "Activity Based Chemical Proteomics: Profiling Proteases as Drug Targets." Current Drug Discovery Technologies 5, no. 3 (September 1, 2008): 200–212. http://dx.doi.org/10.2174/157016308785739866.

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50

Dearman, R. J., and I. Kimber. "106 Cytokine profiling of chemical allergens: Inter-animal variation." Toxicology Letters 144 (September 2003): s31. http://dx.doi.org/10.1016/s0378-4274(03)90105-6.

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