Academic literature on the topic 'Chemical profiling'
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Journal articles on the topic "Chemical profiling"
Piotrowski, Jeff S., Chuek Hei Ho, and Charles Boone. "The Awesome Power of Synergy from Chemical-Chemical Profiling." Chemistry & Biology 17, no. 8 (August 2010): 789–90. http://dx.doi.org/10.1016/j.chembiol.2010.08.002.
Full textImran, Ali, Masood Sadiq Butt, Mian Kamran Sha, and Javed Iqbal Sult. "Chemical Profiling of Black Tea Polyphenols." Pakistan Journal of Nutrition 12, no. 3 (February 15, 2013): 261–67. http://dx.doi.org/10.3923/pjn.2013.261.267.
Full textLewis, Melissa M., Yi Yang, Ewa Wasilewski, Hance A. Clarke, and Lakshmi P. Kotra. "Chemical Profiling of Medical Cannabis Extracts." ACS Omega 2, no. 9 (September 22, 2017): 6091–103. http://dx.doi.org/10.1021/acsomega.7b00996.
Full textMazák, Károly, Sándor Hosztafi, Márta Kraszni, and Béla Noszál. "Physico-chemical profiling of semisynthetic opioids." Journal of Pharmaceutical and Biomedical Analysis 135 (February 2017): 97–105. http://dx.doi.org/10.1016/j.jpba.2016.12.014.
Full textHorning, Benjamin D., Radu M. Suciu, Darian A. Ghadiri, Olesya A. Ulanovskaya, Megan L. Matthews, Kenneth M. Lum, Keriann M. Backus, Steven J. Brown, Hugh Rosen, and Benjamin F. Cravatt. "Chemical Proteomic Profiling of Human Methyltransferases." Journal of the American Chemical Society 138, no. 40 (September 30, 2016): 13335–43. http://dx.doi.org/10.1021/jacs.6b07830.
Full textMartin, Brent R. "Chemical approaches for profiling dynamic palmitoylation." Biochemical Society Transactions 41, no. 1 (January 29, 2013): 43–49. http://dx.doi.org/10.1042/bst20120271.
Full textTHORNTON, JOHN I. "DNA Profiling." Chemical & Engineering News 67, no. 47 (November 20, 1989): 18–30. http://dx.doi.org/10.1021/cen-v067n047.p018.
Full textBadea, Georgiana Ileana, Ioana Diaconu, and Gabriel Lucian Radu. "Organic Acids Chemical Profiling in Food Items." Revista de Chimie 68, no. 6 (July 15, 2017): 1147–52. http://dx.doi.org/10.37358/rc.17.6.5631.
Full textLagurin, L. G., M. O. Galingana, J. D. J. Magsalin, J. E. S. Escaño, and F. M. Dayrit. "Chemical profiling of Philippine Moringa oleifera leaves." Acta Horticulturae, no. 1158 (April 2017): 257–68. http://dx.doi.org/10.17660/actahortic.2017.1158.29.
Full textImran, Muhammad, Masood Sadiq Butt, Faqir Muhammad Anjum, and Javed Iqbal Sultan. "Chemical Profiling of Different Mango Peel Varieties." Pakistan Journal of Nutrition 12, no. 10 (September 15, 2013): 934–42. http://dx.doi.org/10.3923/pjn.2013.934.942.
Full textDissertations / Theses on the topic "Chemical profiling"
Ogunleye, Olatokumbo Olajumi Luca. "Chemical Inducers of Dimerization for Profiling Protein Kinases." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/579019.
Full textPUNZALAN, LOUVY LYNN CALVELO. "Chemoproteomic Profiling of a Pharmacophore-Focused Chemical Library." Kyoto University, 2020. http://hdl.handle.net/2433/259001.
Full textPeterson, Vanessa M. (Vanessa Marie). "Detecting and molecular profiling cancer cells in patients." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/86863.
Full text"September 2013." Page 173 blank. Cataloged from PDF version of thesis.
Includes bibliographical references (pages 152-163).
Although tumor cells obtained from human patients by surgical biopsy, image-guided intervention, blood draws or fluid drainage (paracentesis, thoracentesis) are a valuable source for analyzing tumor cells, conventional means of proteomic analysis are limited. Highly sensitive and quantitative technologies for point-of-care and multiplexed analysis on small sample sizes are in great demand. To this end, we developed three technologies to improve our understanding of the molecular signatures of cancer in clinical samples. In the first section, we describe a diagnostic magnetic resonance (DMR) device that was developed for point-of-care analyses of human tumors. We optimized a magnetic nanoparticle assay to improve sensitivity and robustness of the DMR approach. The DMR device was tested by analyzing samples from 50 patients. The results were then validated in an independent cohort of 20 additional patients. DMR enabled quantification of multiple protein markers in all patients. Using a four-protein signature enabled us to achieve 96% accuracy for establishing cancer diagnosis, surpassing conventional clinical analysis by immunohistochemistry. Results also show that protein expression patterns decay with time, underscoring the temporal need for rapid sampling and diagnoses. Also, a surprising degree of heterogeneity in protein expression both across different patient samples and even within the same tumor was observed, which has important implications for molecular diagnostics and therapeutic drug targeting. In the second section we molecularly profiled tumor cells in ascites - peritoneal fluid frequently drained for symptomatic relief in advanced ovarian cancer (OvCA) patients. First, we profiled a comprehensive panel of 85 biomarkers in ovarian cancer and benign cell lines. From this data set, 31 markers were identified and profiled in a training set of human ascites samples (n=1 8). We identified an ascites-derived tumor signature termed ATCdx containing four markers which was then validated in a cohort of 47 patients (33 ovarian cancer and 14 control) and correctly identified all 33 ovarian cancer patients. Serial samples were obtained from a subset of patients' serial samples (n=7) and profiled, demonstrating that ATCs can be used to measure treatment response and differentiate responders from non-responders. Finally, we specifically designed a novel microfluidic enrichment chip that allows rapid visualization of cancer cells in heterogeneous ascites fluid. This chip requires small sample volumes (< 1 mL) and has single cell detection sensitivity. Furthermore, it is inexpensive to construct and can be easily fabricated using soft lithographic techniques, providing a point-of-care method that could potentially find widespread use for ATC analyses and diagnosis. In the final section, a multiplexed proteomic assay using a photocleavable DNA barcoding method was developed to multiplex protein detection in single cells. We tested 94 antibodies against common cancer markers to examine different treatment responses and heterogeneity at the single cell level. We then extended our analysis to human clinical samples to demonstrate the potential of protein-based measurements to assist in monitoring cancer therapy through differential changes before and after treatment. We show that protein based tumor profiles can provide sufficient information to predict treatment response. Finally, we examined interpatient variability and intratumoral heterogeneity of single cells with this highly sensitive assay. Together, these technologies can help overcome current clinical limitations and expedite advancements in cancer treatment.
by Vanessa M. Peterson.
Ph. D.
Kabbani, Nazir. "Chemical-genetic profiling of platelet-activating factor in yeast." Thesis, University of Ottawa (Canada), 2009. http://hdl.handle.net/10393/28189.
Full textGoudsmits, E. "Chemical profiling of ballistic materials : analysis of organic gunshot residue." Thesis, Liverpool John Moores University, 2018. http://researchonline.ljmu.ac.uk/8454/.
Full textChen, Zewei. "Authentication of Complex Botanical Materials by Chemometrics and Chemical Profiling." Ohio University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1617010785195628.
Full textCharlton, Thomas. "Chemical proteomic profiling to investigate lipoprotein biogenesis in Clostridium difficile." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/29661.
Full textSilva, Saliya Sudharshana 1976. "Transcriptional profiling and flux measurements of polyhydroxybutyrate production in Synechocystis." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/28657.
Full textIncludes bibliographical references (leaves 39-41).
(cont.) to determine the CO₂ uptake rates and PHB production rates of strains engineered for enhanced CO₂ fixation and PHB production respectively.
The metabolism of Synechocystis PCC6803 cells has been investigated using full-genome DNA micro-arrays and C14 tracer techniques. Full-genome (3169 genes) DNA micro-arrays were used to probe transcript levels of Synechocystis cells grown under a variety of medium conditions. Canonical discriminant analysis was used to identify transcript levels that allowed discrimination between growth media conditions, and allowed predictions of polyhydroxybutyrate (PHB) levels. Phosphate-related genes were found to alter in response to phosphate limitation and were found to include differentially regulated multi-gene families. Nitrogen-related genes were not found to be substantially reflective of nitrogen limitation under the conditions studied. Finally, transcription of PHA biosynthetic pathway genes were found to reflect the media conditions of greatest PHB accumulation, suggesting that constitutive over-expression of the PHA biosynthetic genes may lead to greater PHB accumulation levels. A methodology using C14 tracers was developed for the accurate measurement of CO₂ uptake rates and the partitioning of the fixed carbon into different biosynthetic fractions. These techniques were applied to the characterization of WT Synechocystis cells in late exponential phase. A stoichiometric model of Synechocystis metabolism was used to determine constraints between the measurements. A balance on C14 counts was obtained and significant levels of secreted compounds were not detected. The measured carbon fixation rates were found to be consistent with the observed growth rates, but inconsistent with measurements of oxygen evolution in the light and uptake in the dark made using a Clarke Electrode apparatus. These techniques may be used in future studies
by Saliya Sudharshana Silva.
S.M.
Kates, Lisa Natasha. "Chemical profiling and environmental modelling of waste from clandestine methylamphetamine laboratories." Thesis, University of Strathclyde, 2013. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=22542.
Full textTaylor, Michael. "To F-SIMS/XPS chemical depth profiling of synthetic polymer hydrogels." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/38755/.
Full textBooks on the topic "Chemical profiling"
Instrument Development for Atmospheric Research and Monitoring: Lidar Profiling, Doas and Tunable Diode Laser Spectroscopy (Transport and Chemical Transformation ... of Pollutants in the Troposphere, V. 8). Springer, 1997.
Find full textJones, Rebecca. Green Harvest. CSIRO Publishing, 2010. http://dx.doi.org/10.1071/9780643101074.
Full textBook chapters on the topic "Chemical profiling"
Bastasz, R. "Hydrogen Profiling in Titanium." In Springer Series in Chemical Physics, 397–99. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-82724-2_106.
Full textShepherd, F. R., W. Vandervorst, W. M. Lau, W. H. Robinson, and A. J. SpringThorpe. "SIMS Depth Profiling of Si in GaAs." In Springer Series in Chemical Physics, 350–52. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-82724-2_93.
Full textHuber, Kilian V. M., and Giulio Superti-Furga. "Profiling of Small Molecules by Chemical Proteomics." In Methods in Molecular Biology, 211–18. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-3341-9_15.
Full textv. Criegern, R., and I. Weitzel. "SIMS Depth Profiling with Oblique Primary Beam Incidence." In Springer Series in Chemical Physics, 319–22. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-82724-2_84.
Full textRobinson, W. H., and J. D. Brown. "Depth Profiling of Dopants in Aluminum Gallium Arsenide." In Springer Series in Chemical Physics, 357–59. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-82724-2_95.
Full textHannoush, Rami N. "Profiling Cellular Myristoylation and Palmitoylation Using ω-Alkynyl Fatty Acids." In Chemical Genomics and Proteomics, 85–94. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-349-3_7.
Full textSułkowska-Ziaja, Katarzyna, Katarzyna Kała, Jan Lazur, and Bożena Muszyńska. "Chemical and Bioactive Profiling of Wild Edible Mushrooms." In Fungal Biology, 129–57. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-02622-6_6.
Full textBryan, S. R., D. P. Griffis, R. W. Linton, and W. J. Hamilton. "Digital Slit Imaging for High-Resolution SIMS Depth Profiling." In Springer Series in Chemical Physics, 239–41. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-82724-2_63.
Full textBoudewijn, P. R., and H. W. Werner. "Quantitative SIMS Depth Profiling of Semiconductor Materials and Devices." In Springer Series in Chemical Physics, 270–78. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-82724-2_71.
Full textSchulte, F., and M. Maier. "Temperature Dependent Broadening Effects in Oxygen SIMS Depth Profiling." In Springer Series in Chemical Physics, 285–87. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-82724-2_74.
Full textConference papers on the topic "Chemical profiling"
Moremi, P., GP Kamatou, W. Chen, and A. Viljoen. "Chemical profiling of Croton gratissimus Burch." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399752.
Full textHan, Ju, Seema Singh, Lan Sun, Blake Simmons, Manfred Auer, and Bahram Parvin. "Chemical profiling of the plant cellwall through Raman microspectroscopy." In 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro. IEEE, 2010. http://dx.doi.org/10.1109/isbi.2010.5490228.
Full textWang, Huijun, Francisco Garcia, An Chi, Ivan Cornella Taracido, Anne Mai Wasssermann, and Andy Liaw. "Profiling Diverse Chemical Space to Map the Druggable Proteome." In BCB '18: 9th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics. New York, NY, USA: ACM, 2018. http://dx.doi.org/10.1145/3233547.3233624.
Full textLin, Chiao-Chi, Peter J. Krommenhoek, Stephanie S. Watson, and Xiaohong Gu. "Chemical depth profiling of photovoltaic backsheets after accelerated laboratory weathering." In SPIE Solar Energy + Technology, edited by Neelkanth G. Dhere, John H. Wohlgemuth, and Rebecca Jones-Albertus. SPIE, 2014. http://dx.doi.org/10.1117/12.2066400.
Full textBawase, Moqtik, Yogesh Sathe, Suhail Mulla, and Sukrut S. Thipse. "Chemical Profiling of Exhaust Particulate Matter from Indian In-Service Vehicles." In Symposium on International Automotive Technology. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2021. http://dx.doi.org/10.4271/2021-26-0192.
Full textBittner, M., A. Springer, R. Schenk, and MF Melzig. "Cultivation of Black Cohosh: Non-targeted Chemical Profiling and Comparison to Wild." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608500.
Full textFikry, SM, NH Khalil, and OM Salama. "Chemical profiling, biostatic and biocidal dynamics of Origanum vulgare L. essential oil." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399870.
Full textGu, Xiaohong, Chiao-Chi Lin, Peter J. Krommenhoek, Yadong Lyu, Jae Hyun Kim, Li-Chieh Yu, Tinh Nguyen, and Stephanie S. Watson. "Depth profiling of chemical and mechanical degradation of UV-exposed PV backsheets." In 2016 IEEE 43rd Photovoltaic Specialists Conference (PVSC). IEEE, 2016. http://dx.doi.org/10.1109/pvsc.2016.7749560.
Full textGuo, Baoshan, Cheng Lei, Takuro Ito, Yiyue Jiang, Yasuyuki Ozeki, and Keisuke Goda. "High-throughput optofluidic profiling of Euglena gracilis with morphological and chemical specificity." In SPIE/COS Photonics Asia, edited by Ming Li, Bahram Jalali, Keisuke Goda, and Kevin K. Tsia. SPIE, 2016. http://dx.doi.org/10.1117/12.2245836.
Full textMuenmuang, Chotika, Monpilai Narasingha, Theerawut Phusantisampan, and Malinee Sriariyanun. "Chemical Profiling of Morinda Citrifolia Extract From Solvent and Soxhlet Extraction Method." In ICBBS '17: 6th International Conference on Bioinformatics and Biomedical Science. New York, NY, USA: ACM, 2017. http://dx.doi.org/10.1145/3121138.3121194.
Full textReports on the topic "Chemical profiling"
Tuncay Aktosun. Chemical Depth Profiling from Neutron Reflectometry. Office of Scientific and Technical Information (OSTI), March 2006. http://dx.doi.org/10.2172/877659.
Full textHanson, Alfred K., Percy L. Donaghay, Casey Moore, and Richard Arrieta. Transitioning Submersible Chemical Analyzer Technologies for Sustained, Autonomous Observations from Profiling Moorings, Gliders and other AUVs. Fort Belvoir, VA: Defense Technical Information Center, January 2008. http://dx.doi.org/10.21236/ada496460.
Full textMichel Bonin, Tom Harvill, Jared Hoog, Don Holve, Alan Alsing, Bob Clark, and Steve Hrivnak. "A High Speed Laser Profiling Device for Refractory Lininig Thickness Measurements In a Gasifier with Cross-Cut to the Metals, Forest Products, Chemical and Power Generation Industries". Office of Scientific and Technical Information (OSTI), November 2007. http://dx.doi.org/10.2172/963420.
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