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Dissertations / Theses on the topic 'Chemical engineers'

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1

Gissing, Philip School of Science &amp Technology Studies UNSW. "Sir Philip Baxter, Engineer: The Fabric of a Conservative Style of Thought." Awarded by:University of New South Wales. School of Science and Technology Studies, 1999. http://handle.unsw.edu.au/1959.4/17017.

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This thesis is concerned with the life and career of Sir Philip Baxter (1905-1989), particularly during the period following his arrival in Australia from England in 1950. But the thesis is not a conventional biographical study in terms of either the sources used or its guiding themes. Instead, my subject's values and attitudes are portrayed as reflections of a 'conservative style of thought', a concept developed by Karl Mannheim. This approach, centred on close readings of key texts, permits a deeper understanding of a figure who polarised opinion over a long career as Chairman of the Austral
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2

Merchant, Shamel Sarfaraz. "Molecules to engines : combustion chemistry of alcohols and their application to advanced engines." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/98711.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2015.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 237-266).<br>A major challenge in energy is the identification of viable liquid fuels as alternatives to petroleum-based fuels. There are a wide variety of candidate fuels to select from and assessing each new fuel is far from trivial. Small variations in chemical structure can cause large changes in a fuel's performance. Simultaneously, engine designs are also changing rapidly. Accurately predicting how new fuel
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Brunelli, Andrea <1984&gt. "Advanced physico-chemical characterization of engineered nanomaterials in nanotoxicology." Doctoral thesis, Università Ca' Foscari Venezia, 2013. http://hdl.handle.net/10579/4656.

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L'ampio utilizzo di nanomateriali ingegnerizzati (ENM) in svariati prodotti sta suscitando una crescente attenzione sull potenziale rischio di ENM nei confronti della salute umana e l'ambiente. Nonostante le indagini tossicologiche fin qui condotte, solo in poche di esse è stata condotta la caratterizzazione di ENM prima, durante e dopo i test tossicologici. In questa tesi, all’interno del progetto europeo EU-FP7 (ENPRA) e nazionale (PRIN 2009), è stata effettuata una caratterizzazione completa di alcuni più diffusi ENM (i.e. n-TiO2, n-ZnO, n-Ag e MWCNT). In primo luogo, sono stati aggiornati
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4

Kuforiji, Folashade. "The investigation of surface chemical and nanotopographical cues to engineer biointerfaces." Thesis, Keele University, 2015. http://eprints.keele.ac.uk/2351/.

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This thesis is focused on understanding the fundamental physical interaction occurring, when a material interacts with a biological fluid containing protein molecules and cells. The interaction of proteins with defined surface chemistry and nanotopography is of major interest in the field of biomaterials. Despite the degree of research undertaken to study this interface, there is still a lack of understanding of how the protein layer evolves with respect to surface parameters, and further how cells condition the surface. By understanding these processes, advanced biomaterial coatings may be de
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Miller, Shannon L. "Theory and implementation of low-irreversibility chemical engines /." May be available electronically:, 2009. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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6

Tseng, Hsien-Chung Ph D. Massachusetts Institute of Technology. "Production of pentanol in metabolically engineered Escherichia coli." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/65767.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2011.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 149-160).<br>Public concerns about global warming and energy security contribute to an ever-increasing focus on biologically-derived fuels, leading to significant interest in several candidate molecules capable of complementing petroleum-derived fuel resources. Ethanol, one of the most developed biofuels, is used extensively as a gasoline additive. However, the high water miscibility of ethanol creates corrosion problem
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Algharrawi, Khalid Hussein Rheima. "Production of methlxanthines by metabolically engineered E. coli." Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/5904.

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Methylxanthines are natural and synthetic compounds found in many foods, drinks, pharmaceuticals, and cosmetics. Aside from caffeine, production of many methylxanthines is currently performed by chemical synthesis. This process utilizes many chemicals, multiple reactions, and different reaction conditions, making it complicated, environmentally dissatisfactory, and expensive, especially for monomethylxanthines and paraxanthine. In this work, we developed a novel biocatalytic platform for the production of methylxanthines from economic feedstocks; bench scale production of three different methl
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Domagalski, Jakub. "Electrochemically engineered anodic alumina Nanotubes: physico-chemical properties and Applications." Doctoral thesis, Universitat Rovira i Virgili, 2021. http://hdl.handle.net/10803/671688.

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Des del seu descobriment, l'alúmina anòdica porosa s’ha utilitzat com a recobriment protector. El descobriment de la seva estructura porosa va animar els investigadors a desenvolupar nous mètodes de fabricació d'alúmina, obtenint així geometries complexes de propietats diverses. En aquesta tesi es desenvolupen nanotubs d'alúmina anòdica (AANTs) mitjançant un procés d’anodització que es coneix com anodització per polsos. El procés consisteix a entrellaçar polsos de corrent de baixa (~6 mA/cm2) i alta (~290-390 mA/cm2) densitat. Un flux de corrent prou alt produeix un estrenyiment vertical dels
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Basim, Gul Bahar. "Formulation of engineered particulate systems for chemical mechanical polishing applications." [Gainesville, Fla.] : University of Florida, 2002. http://purl.fcla.edu/fcla/etd/UFE1001115.

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10

Khan, Ahmed Faraz. "Chemical kinetics modelling of combustion processes in SI engines." Thesis, University of Leeds, 2014. http://etheses.whiterose.ac.uk/7554/.

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The need for improving the efficiency and reducing emissions is a constant challenge in combustion engine design. For spark ignition engines, these challenges have been targeted in the past decade or so, through ‘engine downsizing’ which refers to a reduction in engine displacement accompanied by turbocharging. Besides the benefits of this, it is expected to aggravate the already serious issue of engine knock owing to increased cylinder pressure. Engine knock which is a consequence of an abnormal mode of combustion in SI engines, is a performance limiting phenomenon and potentially damaging to
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11

Li, Cheri Yingjie. "Engineered microtissue platforms for modeling human pathophysiology and drug metabolism." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/81683.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2013.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 139-160).<br>Over 50% of all drug candidates entering clinical trials are abandoned due to insufficient efficacy or unexpected safety issues despite extensive pre-clinical testing. Liver metabolites that cause toxicity or other side effects cannot always be predicted in animals, in part because of human-specific drug metabolism. Furthermore, while the clinical need for cancer drugs is increasing, anti-tumor activity in
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12

Tam, Brooke Elizabeth. "DNA methylation detection using an engineered methyl-CpG-binding protein." Thesis, Massachusetts Institute of Technology, 2018. https://hdl.handle.net/1721.1/121898.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2018<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 96-103).<br>DNA methylation, specifically the methylation of cytosine bases, is an important biomarker, as abnormal DNA methylation patterns are found in many different types of cancer. Currently, a small number of cancer hospitals evaluate the methylation status of the MGMT gene promoter to determine the best course of treatment for patients with glioblastoma. However, improved methylation detection techniques ar
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De, almeida Tania. "Impact d’une espèce ingénieure de l’écosystème et son utilisation en restauration écologique : Le cas de Messor barbarus (L.) dans les pelouses méditerranéennes Above- and below-ground effects of an ecosystem engineer ant in Mediterranean dry grasslands Harvester ants as ecological engineers for Mediterranean grassland restoration: impacts on soil and vegetation A trait-based approach to promote ants in restoration ecology." Thesis, Avignon, 2020. http://www.theses.fr/2020AVIG0358.

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L’objectif principal de cette thèse était double : (i) mesurer l’impact d’une espèce de fourmi sur son écosystème, afin (ii) d’en déduire des applications potentielles dans le domaine de la restauration écologique.Les fourmis sont parmi les organismes les plus abondants des écosystèmes terrestres et occupent des zones géographiques très variées. Elles jouent des rôles écologiques clés dans de nombreux écosystèmes comme ingénieurs du sol, prédateurs ou régulateurs de la croissance et de la reproduction des plantes. Cependant les données collectées localement sont souvent parcellaires et ne perm
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Rafique, Nasir. "Engineered functional films for photo-electro-chemical sensing of environmental matters." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2023. https://ro.ecu.edu.au/theses/2672.

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The identification and detection of harmful substances in various matrices has gained significant attention due to the negative impacts they have on human health and aquatic life. To address this issue, various analytical techniques have been developed and utilized by monitoring agencies and regulatory bodies. However, many of these techniques are complex, costly and require specialized equipment and trained personnel to operate. Furthermore, the large and cumbersome nature of these techniques makes it difficult to conduct measurements in the field. Additionally, some of these techniques may n
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15

Єрмак, Аліна Володимирівна. "Education and personal skills of a chemical technology engineer in the 21st century." Thesis, Київський національний університет технологій та дизайну, 2020. https://er.knutd.edu.ua/handle/123456789/15295.

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16

Angelos, John P. (John Phillip). "Fuel effects in homogeneous charge compression ignition (HCCI) engines." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/50615.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2009.<br>Includes bibliographical references (p. 209-217).<br>Homogenous-charge, compression-ignition (HCCI) combustion is a new method of burning fuel in internal combustion (IC) engines. In an HCCI engine, the fuel and air are premixed prior to combustion, like in a spark-ignition (SI) engine. However, rather than using a spark to initiate combustion, the mixture is ignited through compression only, as in a compression-ignition (CI) engine; this makes combustion in HCCI engines much more sensitive to fuel
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Tsekenis, Stylianos-Alexios. "High speed chemical species tomography for advanced fuels and engines." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/high-speed-chemical-species-tomography-for-advanced-fuels-and-engines(2ea2e7eb-c3e7-4fe9-96c1-a01d7e4c4a04).html.

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Current research in CI combustion aims to reduce PM and NOx emissions by controlling mixture homogeneity. Low CN fuels are suitable due to their auto-ignition resistance, but the in-cylinder mixture stratification level must be carefully visualised and controlled. Numerous diagnostic techniques exist for imaging the in-cylinder hydrocarbon species concentration. Tomographic techniques based on spectroscopic modalities are minimally-intrusive and able to target species of interest even in multi-component fuel blends. The high-speed CST technique applied in this work is based on the NIRAT modali
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18

Prevo, Brian Geoffrey. "ENGINEERED DEPOSITION OF FUNCTIONAL COATINGS FROM MICRO- AND NANOPARTICLES USING CONVECTIVE ASSEMBLY." NCSU, 2006. http://www.lib.ncsu.edu/theses/available/etd-11202005-150427/.

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The potential technological applications of micro- and nanoparticle coatings necessitate the development of rapid, inexpensive and easily controlled deposition procedures. We have developed a technique for making structured thin films from micro- and nanoparticles by dragging on a substrate a liquid meniscus at constant velocity. The advantages of this technique are improved process speed, efficiency and reduced material consumption relative to standard dip coating techniques. The governing mechanism of the deposition process was found to be convective assembly at high volume fractions. Unifor
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Augustine, Chad R. "Hydrothermal spallation drilling and advanced energy conversion technologies for Engineered Geothermal Systems." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/51671.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2009.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Includes bibliographical references.<br>The purpose of this research was to study the various factors affecting the economic and technical feasibility of Engineered Geothermal Systems, with a special emphasis on advanced drilling technologies. The first part of the thesis was devoted to modeling and analysis of the technologies used to develop EGS proj
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20

Rickard, Jonathan James Stanley. "Advanced micro-engineered platforms for novel device technologies." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8303/.

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The objectives of this thesis are to explore, design, fabricate and implement the use of advanced micro-engineered platforms to be exploited as versatile, novel device technologies. An increasing number of technologies require the fabrication of conductive structures on a broad range of scales and large areas. Here, we introduce advanced yet simple electrohydrodynamic lithography for patterning conductive polymers directly on a substrate with high-fidelity. We illustrate the generality of this robust, low-cost method by structuring thin films via electric-field-induced instabilities, yielding
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21

Pitukmanorom, Pemakorn 1976. "Nanocomposites for nitrogen oxide emissions control in lean-burn engines." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/28848.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2004.<br>Includes bibliographical references.<br>(cont.) reducing agent than propane in the SCR of NO. Pt-Rh/CuO/A1₂O₃ nanocomposites capable of adsorbing SO₂ in oxygen-rich environment as metal sulfates and releasing SO₂ in reducing atmosphere were synthesized with sequential precipitation technique. These CuO-based sorbents possessed excellent SO₂ adsorption capacity and superior regenerability by CO compared to those produced by the impregnation method due to higher surface area and dispersion of Cu speci
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22

Park, Kyoo Chul. "Physico-chemical hydrodynamics of droplets on textured surfaces with engineered micro/nanostructures." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/81704.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2013.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>Understanding physico-chemical hydrodynamics of droplets on textured surfaces is of fundamental and practical significance for designing a diverse range of engineered surfaces such as low-reflective, self-cleaning or anti-fogging glass, easy-cleaning robust inkjet printer heads, or efficient fog-harvesting surfaces. Developing such functional surfaces requires interdisciplinary considerations that have not been broadl
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Moon, Tae Seok. "Retrobiosynthesis of D-glucaric acid in a metabolically engineered strain of Escherichia coli." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/57868.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, February 2010.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 173-181).<br>Synthetic biology is an evolving field that emphasizes synthesis more than observation which has been and is the scientific method for traditional biology. With powerful synthetic tools, synthetic biologists seek to reproduce natural behaviors (and eventually to create artificial life) from unnatural molecules or try to construct unnatural systems from interchangeable parts. Accompanied with this r
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Kalezi, Artemis. "Tissue-engineered liver microreactor as an in vitro surrogate assay for gene delivery." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/38981.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2007.<br>Includes bibliographical references.<br>The lack of correlation between in vitro and in vivo gene delivery experiments presents a significant obstacle in the progress of gene therapy studies by preventing the extrapolation of successful cell culture results into animals. This phenomenon has also been documented in the specific case of liver where standard hepatocyte culture systems fail to reliably predict the in vivo performance of gene delivery vectors. This is possibly a consequence of the loss o
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Hsieh, Vivian Ph D. Massachusetts Institute of Technology. "High relaxivity biomolecule based contrast agents engineered for molecular functional magnetic resonance imaging." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104206.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 71-84).<br>Magnetic resonance imaging (MRI) is a powerful neuroimaging tool that allows non-invasive visualization of the brain with high spatial and temporal resolution. Research on MRI contrast agents and their application to problems in neuroscience is burgeoning, and there is particular interest in developing MRI agents that are sensitive to time varying components of neurophysiology. Relatively recent advanc
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Liu, Zhen. "Chemical kinetics modelling study on fuel autoignition in internal combustion engines." Thesis, Loughborough University, 2010. https://dspace.lboro.ac.uk/2134/6533.

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Chemical kinetics has been widely acknowledged as a fundamental theory in analysis of chemical processes and the corresponding reaction outputs and rates. The study and application of chemical kinetics thus provide a simulation tool to predict many characteristics a chemical process. Oxidation of hydrocarbon fuels applied in internal combustion engines is a complex chemical process involving a great number of a series of chained reaction steps and intermediate and simultaneous species. Symbolic and Numerical description of such a chemical process leads to the development and application of che
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Sidhu, J. S. "The acceptability of alcohol fuels for automobile engines." Thesis, Aston University, 1988. http://publications.aston.ac.uk/9714/.

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The aim of this project was to carry out an investigastion into suitable alternatives to gasoline for use in modern automobiles. The fuel would provide the western world with a means of extending the natural gasoline resources and the third world a way of cutting down their dependence on the oil producing countries for their energy supply. Alcohols, namely methanol and ethanol, provide this solution. They can be used as gasoline extenders or as fuels on their own.In order to fulfil the aims of the project a literature study was carried out to investigate methods and costs of producing these fu
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Gibson, Gillian Hutton. "The development of chemically engineered pullulan for drug delivery." Thesis, University of Greenwich, 2007. http://gala.gre.ac.uk/6174/.

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Pullulan has been chemically modified by the incorporation of various hydrophobic molecules, to produce two types of derivatives (hydrophobically modified carboxymethyl pullulans (HMCMPs), and crosslinked carboxymethyl pullulan). The foregoing modifications were performed in two steps from the parent pullulan. The first step involved carboxylation of pullulan with sodium chloroacetate yielding carboxymethyl pullulan (CMP). The second step involved the medication of CMP by coupling different amine functionalized molecules onto the carboxylic groups of CMP, using the coupling agent dicyclohexylc
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Wudebwe, Uchena Nomusa Geraldine. "Factors influencing the development of a tissue engineered bone to bone ligament." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5719/.

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This thesis aimed to quantify the effect of anabolic agents ascorbic acid (AA)/ proline (P) on the rates of contraction of the fibrin hydrogel scaffold as well as develop a process for increasing construct collagen content, tensile strength and widths. Supplementation with AA/ P, in combination or individually, revealed contrasting effects on the rates of fibrin gel contraction dependent on concentration and culture duration. There appeared to be strong correlations between the extents of contraction and construct collagen content. Enhancing the stiffness of the fibrin hydrogel augmented width
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CODAZZI, VERA. "Breaking phylogenetic barriers for fine and bulk chemical products in engineered Saccharomyces cerevisiae." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2011. http://hdl.handle.net/10281/19692.

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Industrial biotechnologies allow today to obtain both fine and bulk chemicals and yeasts as cell factories can produce many products belonging to both field (Branduardi et al., 2008, Porro and Branduardi, 2009). Among yeasts, Saccharomyces cerevisiae still represents the microorganism of election to develop such cell factories. As regard bioethanol production, yeasts utilization is well established for its natural fermentation ability, but new generation biofuels require the development of strain more and more robust, able to face conditions imposed by the process that should be as ch
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Wu, Kuo-chʻun 1968. "Chemical kinetic modeling of oxidation of hydrocarbon emissions in spark ignition engines." Thesis, Massachusetts Institute of Technology, 1994. http://hdl.handle.net/1721.1/35377.

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Du, Yinming. "High-Yield and High-Titer n-Butanol Production from Lignocellulosic Feedstocks by Metabolically Engineered Clostridium tyrobutyricum." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1374193011.

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Kotta, Linda Thokozile. "Structural conditioning and mediation by student agency : a case study of success in chemical engineerng design." Doctoral thesis, University of Cape Town, 2011. http://hdl.handle.net/11427/11475.

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Ncongwane, Mpendulo S. "Assessment of the potential carbon footprint of engineered processes for the mineral carbonation of PGM tailings." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20951.

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Mineral carbonation is a carbon sequestration technology that entails the reaction of CO2 with oxides or silicates of magnesium, calcium or iron to produce stable carbonate compounds. Magnesium-rich tailings from the platinum industry in South Africa have been identified as a potentially viable and attractive feedstock for CO2 sequestration through mineral carbonation. Many of the strategies proposed to enhance the dissolution kinetics of silicate minerals, such as the use of elevated temperatures and pressures and chemical additives, as well as pretreatment through mechanical and thermal acti
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Chang, Wei-Lun. "Acetone-Butanol-Ethanol Fermentation by Engineered Clostridium beijerinckii and Clostridium tyrobutyricum." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1282108408.

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Asghari, Adib Ali. "Interactions of Engineered Silica Nanoparticles with Cell Membrane Models." Ohio University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1501764587639053.

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Timar, Maria Cristina. "Chemically modified wood for thermally formed composites." Thesis, Bucks New University, 1998. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.714440.

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Zhou, Zilan. "Engineered Nanoparticle for Targeted and Controlled Drug Delivery." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1505831582487098.

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Jabbarzadeh, Ehsan Abrams Cameron F. Laurencin Cato T. "Theoretical and experimental approaches to control blood vessel growth into tissue engineered scaffolds /." Philadelphia, Pa. : Drexel University, 2007. http://hdl.handle.net/1860/1794.

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Li, Xin. "Kinetic study and modelling of ethanol production from glucosexylose mixtures using the genetically-engineered strain Escherichia coli KO11." Thesis, University of Ottawa (Canada), 2008. http://hdl.handle.net/10393/27800.

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Kinetics of ethanol fermentation on different synthetic glucose/xylose mixtures using Escherichia coli KO11 was studied. No substrate inhibition was observed in both glucose-only and xylose-only experiments. In single substrate fermentations, results show that glucose was the preferred substrate and its ethanol conversion rate was 1.5 times higher than the one obtained with xylose. In mixed-sugar fermentations, glucose was fully consumed significantly earlier than xylose, indicating an initial inhibition on xylose fermentation. The xylose consumption rate after the depletion of glucose signifi
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Sivaraman, Anand 1977. "A microfabricated 3D tissue engineered "Liver on a Chip" : information content assays for in vitro drug metabolism studies." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/28661.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2004.<br>Includes bibliographical references (p. 180-195).<br>(cont.) approaches to improving hepatocyte function in culture have been described, not all of the important functions--specifically the biotransformation functions of the liver--can as yet be replicated at desired in ivo levels, especially in culture formats amenable to routine use in drug development. The in vivo microenvironment of hepatocytes in the liver capillary bed includes signaling mechanisms mediated by cell-cell and cell-matrix interac
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Scanferlato, Vjera Sostarec. "Environment risk assessment for toxic chemicals and genetically-engineered microorganisms : a microcosm approach /." Diss., This resource online, 1990. http://scholar.lib.vt.edu/theses/available/etd-07282008-135357/.

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Mantri, Shiksha. "Engineered α-hemolysin pores with chemically and genetically-fused functional proteins". Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:55450bd3-b93f-410f-b795-0110449c0da9.

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Protein engineering could be used to bring two proteins together, which don't normally interact, in an oriented configuration. Using computer modelling and experimental work involving mutagenesis, a new dimer complex, (α7)2, was engineered with two α-hemolysin (αHL) heptamers (α7) units linked via disulfide bridges in a cap-to-cap orientation. The structure of (α7)2 was confirmed by biochemical analysis, transmission electron microscopy (TEM) and single-channel electrical recording. Importantly, it was shown that the one of two transmembrane  barrels of (α7)2 can insert into an attoliter lipo
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Hammerstein, Anne Friederike. "Single-molecule chemistry studies with engineered alpha-hemolysin pores." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:1dd1f11d-2b20-42e9-9dfc-c30498822b77.

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Engineered protein nanopores can be used to investigate a wide range of dynamic processes in real time and at the single-molecule level, for example covalent bond making and breaking or the interaction of ligands with their cognate binding sites. The detection of such processes is accomplished by monitoring the current carried by ions through the pore in an applied potential, which is modulated as molecules of interest interact with engineered binding sites within the pore. In contrast to ensemble measurements, where the behaviour of individual molecules is obscured by averaging, single-channe
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Nazemidashtarjandi, Saeed. "Interactions of Engineered Nanomaterials with the Cell Plasma Membrane." Ohio University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1617363923755762.

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Shim, Min Suk. "Molecularly Engineered Acid-Responsive Polymers for Nucleic Acid Delivery." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1291412851.

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Peng, Yucheng. "EFFECT OF HIGH TEMPERATURES ON ADHESIVE BOND DURABILITY AND TOXIC CHEMICAL PRODUCTION FOR ENGINEERED WOOD PRODUCTS." MSSTATE, 2008. http://sun.library.msstate.edu/ETD-db/theses/available/etd-07082008-153319/.

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The objectives of this research were to investigate the heat resistant performance of a structural adhesive and to analyze the contribution of the adhesive to the chemical emissions from the glued wood products affected by the elevated temperatures. Phenol-resorcinol-formaldehyde (PRF) and two wood species, southern pine (Pinus palustris) and Douglas-fir (Pseudotsuga menziesii), were investigated. The dynamic mechanical analysis (DMA) test results showed that the heat durability performance of cured PRF resin was better than that of the two wood species used in this study. The results indicate
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Tyrologou, Pavlos. "A structural and physico-chemical investigation of mineral/organic composites as novel components of engineered fill." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424391.

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Gothard, David. "Enhanced osteogenic differentiation via chemically engineered aggregation of mouse embryonic stem cells." Thesis, University of Nottingham, 2009. http://eprints.nottingham.ac.uk/10826/.

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The formation of embryoid bodies has long been utilized to initiate differentiation of embryonic stem cells in vitro. The embryoid body provides an effective means of recapitulating early stages during embryogenesis and formation of the three germ layers. Current methodology for embryoid formation is extensive but exhibits a lack of standardisation and coherence. Here is shown a 3D culure system for controlled embryonic stem cell aggregation via a non-cytotoxic cell surface modification and cell-cell cross-linking. Embryoid body formation was found to be a complex relationship between embryoni
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Chandran, Davannendran. "Experimental investigation into the physico-chemical properties changes of palm biodiesel under common rail diesel engine operation for the elucidation of metal corrosion and elastomer degradation in fuel delivery system." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/35228/.

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Compatibility of fuel delivery materials (FDM) with biodiesel fuel in the fuel delivery system (FDS) under real-life common rail diesel engine (CRDE) operation poses a challenge to researchers and engine manufacturers alike. Although standard methods such as ASTM G31 and ASTM D471 for metals and elastomers, respectively, are deemed suitable for evaluating the effects of water content, total acid number (TAN) and oxidation products in biodiesel on FDM degradation, they do not resemble the actual engine operation conditions such as varying fuel pressure/temperature as well as the presence of a w
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