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1

Brovarska, O. S., L. D. Varbanets, and S. V. Kalinichenko. "Chemical Characterization and Biological Activity of Escherichia coli Lipopolysaccharides." Mikrobiolohichnyi Zhurnal 82, no. 6 (November 30, 2020): 35–42. http://dx.doi.org/10.15407/microbiolj82.06.035.

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Lipopolysaccharides (LPS) are specific components of the cell envelope of gram-negative bacteria, located at the external surface of their outer membrane and performing a number of important physicochemical and biological functions. The widespread in nature are representatives of Enterobacteriaceae family. Among them there are saprotrophic, useful human symbionts, as well as causative agents of acute intestinal infections. The role of saprophytic intestinal microbiota is not limited only to its participation in the digestion process. The endotoxin released as a result of self-renewal of the cell pool of Escherichia coli partially enters the portal blood and performs antigenic stimulation of the macroorganism. In addition, a small amount of endotoxin can also be released by live gram-negative bacteria, which, given the large population of E. coli in the intestine, can create a sufficiently high concentration of endotoxin. Aim. The study of composition and biological activity of lipopolysaccharides of new E. coli strains, found in the human body. Methods. The objects of investigation were strains of Escherichia coli, isolated from healthy patients at the epidemiological center in Kharkiv. Lipopolysaccharides were extracted from dried cells by 45% phenol water solution at 65–68°С by Westphal and Jann method. The amount of carbohydrates was determined by phenol-sulfuric method. Carbohydrate content was determined in accordance to the calibration curve, which was built using glucose as a standard. The content of nucleic acids was determined by Spirin method, protein − by Lowry method. Serological activity of LPS was investigated by double immunodiffusion in agar using the method of Ouchterlony. Results. In all studied E. coli LPS (2884, 2890, 2892), glucose was dominant monosaccharide (40.5, 41.1, 67.3%, respectively). LPS also contained rhamnose (1.8, 22.9, 1.6%, respectively), ribose (3.5, 6.1, 3.6%, respectively) and galactose (4.1, 20.2, 18.3%, respectively). E. coli 2884 LPS also contained arabinose (1.0%) and mannose (44.8%), while E. coli strains 2890 and 2892 LPS contained heptose (9.7 and 7.8%, respectively). Lipid A composition was presented by fatty acids with a carbon chain length from C12 to C18. As the predominant components were 3-hydroxytetradecanoic (39.2–51.3%) as well as tetradecanoic (23.1–28.5%), dodecanoic (8.9–10.9%), hexadecanoic (4.3–7.2%) and octadecanoic (1.8–2.4%) acids. Unsaturated fatty acids: hexadecenoic (2.0–17.9%) and octadecenoic (3.4–4.2%) have been also identified. It was found that octadecanoic and octadecenoic acids were absent in the LPS of 2884 and 2892 strains, respectively. In SDS-PAAG electrophoresis, a bimodal distribution typical for S-forms of LPS was observed. The studied LPS were toxic and pyrogenic. Double immunodiffusion in agar by Ouchterlony revealed that the tested LPS exhibited an antigenic activity in the homologous system. In heterologous system E. coli 2892 LPS had cross reactivity with LPS of E. coli 2890 and М-17. Since the structure of the O-specific polysaccharide (OPS) of E. coli M-17 was established by us earlier, the results of serological reactions make it possible to suggest an analogy of the E. coli 2892 and 2890 OPS structures with that of E. coli М-17 and their belonging to the same serogroup. Conclusions. The study of the composition and biological activity of LPS of new strains of Escherichia coli 2884, 2890 and 2892, isolated from the body of almost healthy patients, expands our knowledge about the biological characteristics of the species.
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2

Gao, Yang, Huiyi Huang, Hongyi Zhao, Houqiang Xia, Miao Sun, Pengcheng Li, Cangsong Zheng, Helin Dong, and Jingran Liu. "Phosphorus affects enzymatic activity and chemical properties of cotton soil." Plant, Soil and Environment 65, No. 7 (August 1, 2019): 361–68. http://dx.doi.org/10.17221/296/2019-pse.

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Pot experiments were conducted in 2017 with two cotton cultivars (CCRI 79 and LMY 28) and three phosphorus (P) levels: 3, 8 and 12 mg P<sub>2</sub>O<sub>5</sub>/kg as P<sub>0</sub>, P<sub>1</sub> and P<sub>2</sub>, respectively. In this study, the soil water-soluble organic carbon content increased as the soil available P (AP) increased, while there were no significant variations for soil total organic matter content among the three AP levels. The activities of invertase, cellulase and urease in cotton soil decreased significantly in the P0. There were positive correlations between invertase and cellulose activities with soil organic carbon and inorganic-nitrogen (N); these correlated negatively with soil C/N ratio and AP level. In addition, high soil AP can raise soil AP and enhance alkaline phosphatase activity, which had a significant negative relationship with the soil C/P ratio. Urease activity had a significant positive relationship with soil NH<sub>4</sub><sup>+</sup>-N, C/P and N/P, as well as a negative correlation with soil C/N. Moreover, soil NH<sub>4</sub><sup>+</sup>-N and NO<sub>3</sub><sup>–</sup>-N in the P<sub>1</sub> and P<sub>2</sub> were lower than in the P<sub>0</sub>, which might be an effect of high AP on soil N availability.
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3

Daglia, M., A. Papetti, and G. Gazzani. "Green and roasted coffee antiradical activity stability in chemical systems." Czech Journal of Food Sciences 22, SI - Chem. Reactions in Foods V (January 1, 2004): S191—S194. http://dx.doi.org/10.17221/10658-cjfs.

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The stability to storage at different temperature and oxygen exposure of green and roasted coffee either as coffee beans or as ground coffee antiradical activity, was evaluated. The results showed that the coffee solution antihydroxyl radical activity was constant, independently from the coffee species, from the roasting process, and moreover from the type of storage conditions, suggesting that temperature and oxygen exposure did not affect this antiradical activity. With regard to antiperoxyl radical activity, all green coffee solutions showed remarkable and stable activity. Conversely, the roasted coffee beans and roasted and ground coffee antiperoxyl radical activity started to increase after three month of storage, suggesting that Maillard reaction products affect the stability of such antiradical property.
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4

Oranusi, Solomon, Adeola Onibokun, Oluwatoyosi Afolabi, Chineme Okpalajiaku, Anita Seweje, Bunmi Olopade, and Yemisi Obafemi. "Chemical, microbial and antioxidant activity of Cola lepidota K. Schum fruits." Czech Journal of Food Sciences 38, No. 1 (February 29, 2020): 11–19. http://dx.doi.org/10.17221/360/2018-cjfs.

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This research was to investigate the chemical composition, antioxidant activity, and microbial profiles of Cola lepidota fruits. One hundred grams each of the fruit exocarp, mesocarp and endocarp were blended and analyses were carried out by the following standard methods. Active acidity and vitamin C contents were 5.5 and 6.34 mg 100 g<sup>–1</sup> in endocarp, 4.5 and 14.39 mg 100 g<sup>–1</sup> in mesocarp and 6.7 and 10.02 mg 100 g<sup>–1</sup> for exocarp. Moisture and carbohydrate contents of 12.31 and 68.72% were in the mesocarp while protein and crude fibre contents of 8.13 and 26.18% were in the exocarp and endocarp. Iron (Fe), zinc (Zn) and manganese (Mn) contents were 1.79, 0.27 and 0.57 mg 100 g<sup>–1</sup> in exocarp while lead (Pb), cadmium (Cd) and chromium (Cr) were absent in the endocarp. Predominant isolates were Aspergillus niger, Saccharomyces cerevisiae, Aspergillus flavus, Bacillus, Staphylococcus and Pseudomonas species. C. lepidota had no antimicrobial effect against the tested organisms. Tannins, flavonoids, terpenoids, phenols, coumarins and anthocyanins were present while alkaloids, quinolones, glycosides, steroids and cardiac glycosides were absent. The fruit was observed to have antioxidant property by hydrogen peroxide scavenging activity. This study presents C. lepidota as good for human consumption and can be exploited for animal feed production.
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5

Vasylyshyna, Olena, and Olena Vasylyshyna. "Cherry chemical composition and antioxidant activity under freezing comprehensive relations assessment." Foods and Raw Materials 6, no. 2 (December 20, 2018): 296–304. http://dx.doi.org/10.21603/2308-4057-2018-2-296-304.

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Cherry is a successful combination of sugars, acids, attractive color and taste. However, its shelf life is limited and can be prolonged only with the help of new freezing technologies. Therefore, the gool of this work was to investigate changes in component composition of fresh and frozen cherry. The objects of the research were cherries of the varieties of Shpanka and Lotovka. The studies were carried out with cherries grown in the Central region of Ukraine at the Department of Technology of storage and processing of fruits and vegetables at Uman National Horticulture University. For cherries of both varieties were kept in 20% sugar solution with the addition of 4% ascorutin 1% chitosan for 30 minutes, dried with air flow, frozen at –25°C, packed in 0.5 kg plastic bags, and stored at ‒18°C. For control purposes, nontreated cherries were packed in plastic bags of respective volume. According to the research, preprocessing with 20% sugar solution with the addition of 1% chitosan contributes to preservation of quality and biological value of frozen cherries. Thus antioxidant activity in frozen cherries of Shpanka and Lotovka varieties is 27 and 18 mmol/dm3, ascorbic acid content – 17.6 and 20 mg/100g. So the indexes of quality of cherries for freezing are interrelated and constitute one correlation pattern in which the major index indicator is the content of dry soluble substance and antioxidant activity.
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Souza, Elizângela Maria, Renilde Cordeiro Souza, Mateus Matiuzzi Costa, Carlos Garrido PINHEIRO, Berta Maria HEINZMANN, and Carlos Eduardo COPATTI. "Chemical composition and evaluation of the antimicrobial activity of two essential oils." Boletim do Instituto de Pesca 44, no. 2 (June 6, 2018): 1–4. http://dx.doi.org/10.20950/1678-2305.2018.321.

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7

Zhirkova, Е. V., M. V. Skorokhodova, V. V. Martirosyan, E. F. Sotchenko, V. D. Malkina, and T. A. Shatalova. "CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF CORN HYBRIDS GRAIN OF DIFFERENT PIGMENTATION." Food and Raw Materials 4, no. 2 (December 30, 2016): 85–91. http://dx.doi.org/10.21179/2308-4057-2016-2-85-91.

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8

Devi, Ch Kethani, and Dr D. Gopala Krishna. "Phyto Chemical Screening and Anti-Microbial Activity of Musa Paradisiaca-Fruit Peel." Indian Journal of Applied Research 3, no. 7 (October 1, 2011): 248–49. http://dx.doi.org/10.15373/2249555x/july2013/77.

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9

Teles, Rogerio De Mesquita, Victor Elias Mouchrek Filho, and Adenilde Nascimento. "Chemical Composition and Antibacterial Activity of Essential Oil of Aniba duckei Kosterman." International Journal of Life-Sciences Scientific Research 4, no. 2 (March 2018): 1657–62. http://dx.doi.org/10.21276/ijlssr.2018.4.2.7.

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10

TSUNAKAWA, Sukenari. "Chemical reaction and research activity." Journal of Japan Institute of Light Metals 35, no. 12 (1985): 661–62. http://dx.doi.org/10.2464/jilm.35.661.

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11

Mercer, Andrew C., and Michael D. Burkart. "Chemical expansion of cofactor activity." Nature Chemical Biology 2, no. 1 (January 1, 2006): 8–10. http://dx.doi.org/10.1038/nchembio0106-8.

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12

Costa, Sônia Maria O., Telma Leda G. Lemos, Otília Deusdênial L. Pessoa, Claudia Pessoa, Raquel C. Montenegro, and Raimundo Braz-Filho. "Chemical Constituents fromLippiasidoidesand Cytotoxic Activity." Journal of Natural Products 64, no. 6 (June 2001): 792–95. http://dx.doi.org/10.1021/np0005917.

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13

AGNESE, A. ": antimicrobial activity and chemical study." Phytomedicine 8, no. 5 (2001): 389–94. http://dx.doi.org/10.1078/0944-7113-00059.

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14

Piasecki, A., and B. Burczyk. "Chemical structure and surface activity." Colloid & Polymer Science 263, no. 12 (December 1985): 997–1003. http://dx.doi.org/10.1007/bf01410993.

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15

Schuffenhauer, Ansgar, and Nathan Brown. "Chemical diversity and biological activity." Drug Discovery Today: Technologies 3, no. 4 (December 2006): 387–95. http://dx.doi.org/10.1016/j.ddtec.2006.12.007.

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16

Sokołowski, Adam. "Chemical structure and surface activity." Journal of Colloid and Interface Science 147, no. 2 (December 1991): 496–507. http://dx.doi.org/10.1016/0021-9797(91)90183-9.

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17

Sokolowski, A., A. Piasecki, and B. Burczyk. "Chemical Structure and Surface Activity." Tenside Surfactants Detergents 30, no. 6 (December 1, 1993): 417–21. http://dx.doi.org/10.1515/tsd-1993-300618.

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18

Sokotowski, A. "Chemical Structure and Surface Activity." Tenside Surfactants Detergents 27, no. 2 (March 1, 1990): 103–7. http://dx.doi.org/10.1515/tsd-1990-270211.

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19

Piasecki, A. "Chemical Structure and Surface Activity." Tenside Surfactants Detergents 22, no. 5 (September 1, 1985): 239–43. http://dx.doi.org/10.1515/tsd-1985-220510.

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20

Chang, Christopher J., Tony D. James, Elizabeth J. New, and Ben Zhong Tang. "Activity-Based Sensing: Achieving Chemical Selectivity through Chemical Reactivity." Accounts of Chemical Research 53, no. 1 (January 21, 2020): 1. http://dx.doi.org/10.1021/acs.accounts.9b00542.

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21

Stachulski, Andrew V., John R. Harding, John C. Lindon, James L. Maggs, B. Kevin Park, and Ian D. Wilson. "Acyl Glucuronides: Biological Activity, Chemical Reactivity, and Chemical Synthesis." Journal of Medicinal Chemistry 49, no. 24 (November 2006): 6931–45. http://dx.doi.org/10.1021/jm060599z.

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22

Krzyżaniak, M., and J. Lemanowicz. "Enzymatic activity of the Kuyavia Mollic Gleysols (Poland) against their chemical properties  ." Plant, Soil and Environment 59, No. 8 (July 31, 2013): 359–65. http://dx.doi.org/10.17221/211/2013-pse.

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The research results have shown that the enzyme pH index (0.49&ndash;0.83) confirmed the neutral or alkaline nature of the soils. Neither the changes in the content of available phosphorus nor in the activity of dehydrogenases, catalase, alkaline and acid phosphatase in soil were due to the factors triggering soil salinity; they were a result of the naturally high content of carbon of organic compounds, which was statistically verified with the analysis of correlation between the parameters. There were recorded highly significant values of the coefficients of correlation between the content of available phosphorus in soil and the activity of alkaline (r = 0.96; P &lt; 0.05) and acid phosphatase (r = 0.91; P &lt; 0.05) as well as dehydrogenase (r = 0.90; P &lt; 0.05). To sum up, one can state that Mollic Gleysols in Inowrocław are the soils undergoing seasonal salinity; however, a high content of ions responsible for salinity is balanced with a high content of organic carbon, humus, phosphorus and calcium directly affecting the fertility of the soils analyzed. The activity of the enzymes depended on the natural content of carbon of organic compounds and not on the factors affecting the soil salinity, which points to the potential of such tests for soil environment monitoring.
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23

Dib, M. A., M. Bendahou, A. Bendiabdellah, N. Djabou, H. Allali, B. Tabti, J. Paolini, and J. Costa. "Partial chemical composition and antimicrobial activity of Daucus crinitus Desf. extracts." Grasas y Aceites 61, no. 3 (April 28, 2010): 271–78. http://dx.doi.org/10.3989/gya.122609.

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24

Nahariah, N., H. Hikmah, and F. N. Yuliati. "Antioxidant activity and chemical characteristics in egg albumen fermented by lactid acid bacteria." Journal of the Indonesian Tropical Animal Agriculture 45, no. 3 (June 30, 2020): 214–21. http://dx.doi.org/10.14710/jitaa.45.3.214-221.

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Research on fermentation time and the addition of milk powder to egg albumen is still limited. The purpose of this study was to determine the antioxidant activity and chemical characteristics of fermented egg albumen using different levels of full cream milk powder and different microbial fermentation times. This study used a completely randomized factorial pattern design, 4 x 5 treatments with 4 replications. Research materials include egg albumen, full cream milk powder and mixed Lactic Acid Bacteria (L. bulgaricus, L.achidopillus, and Streptococcus thermopillus). The research treatments were the addition of powdered milk in different level (%) including, 0, 2, 4 and 6. Fermentation times were 0, 12, 24, 36, and 48 h, respectively. The results showed that the addition of powdered milk in different level and fermentation time had no significant effect on the antioxidant activity. The addition of different-level powdered milk was not significant on the glucose content and total protein, but it was very significant (P<0.01) on water content. The fermentation time had a very significant effect (P<0.01) on glucose levels and total protein, but it had no significant effect on the water content of albumen fermentation. Antioxidant activity did not change during the fermentation time and the addition of different-level milk powder. The 24 h fermentation time could reduce the total protein and glucose levels of egg albumen. Adding 2% milk powder could reduce the water content of egg albumen fermentation.
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25

Rizwana, Humaira, Fatimah Al Otibi, and Nouf Al-malki. "Chemical composition, FTIR Studies and Antibacterial Activity of Passiflora edulis f. edulis (Fruit)." Journal of Pure and Applied Microbiology 13, no. 4 (December 30, 2019): 2489–98. http://dx.doi.org/10.22207/jpam.13.4.64.

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26

F, Ângela. "Schinus Terebinthifolius Raddi, Popular Use, Chemical Composition, and Biological Activity: A Systematic Review." Open Access Journal of Veterinary Science & Research 1, no. 4 (2016): 1–10. http://dx.doi.org/10.23880/oajvsr-16000119.

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Introduction: The advance of quantitative and qualitative research has been proving the use of plants as medic ine. Considering that many people are adept at popular practices and Schinus terebinthifolis Raddi is native to South America, abundant in the coastal regions of Brazil, where it is popularly known as ‘aroeira’ (Brazilian peppertree). Objective: Identify the primary studies regarding the popular use, chemical composition, and the main biological activities of Schinus terebinthifolis Raddi. Metodology: This study attempted to identified, through a previous defined methodology, the systematic review, primary studies regarding the popular use, chemical composition, and the main biological activities of Schinus terebinthifolis Raddi. The survey was conducte d in virtual libraries commonly accessed by the scientific community following a script execution and inclusion of some articles. Results: After all steps of selection, we obtained a total of eighty - one, a number of studies on popular use, the chemical co mposition, and biological activities of the plant were achieved. The biological activity found and described for this plant is quite extensive. Thirty - eight works surveyed demonstrate that are several scientifically proven recommendations for using differe nt parts of the plant. Conclusion: This review enabled to systematize the knowledge produced on the main popular use, the main researches related to biological activity, and the range of chemical constituents of Schinus terebinthifolius Raddi already isola ted.
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27

Gobas, Frank A. P. C., Philipp Mayer, Thomas F. Parkerton, Robert M. Burgess, Dik van de Meent, and Todd Gouin. "A chemical activity approach to exposure and risk assessment of chemicals." Environmental Toxicology and Chemistry 37, no. 5 (April 26, 2018): 1235–51. http://dx.doi.org/10.1002/etc.4091.

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28

Yu, Yunie Yeap Soon, Nur Kartinee Kassim, Khalid Hamid Musa, and Aminah Abdullah. "Measurement of Antioxidant Activity and Structural Elucidation of Chemical Constituents from Aglaia oligophylla Miq." International Proceedings of Chemical, Biological and Environmental Engineering 95 (2016): 1–7. http://dx.doi.org/10.7763/ipcbee.2016.v95.1.

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29

Borzova, N. V., and L. D. Varbanets. "Influence of chemical reagents and UV irradiation on the activity of Penicillium canescens ?-galactosidase." Ukrainian Biochemical Journal 90, no. 5 (October 1, 2018): 19–27. http://dx.doi.org/10.15407/ubj90.05.019.

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Abbas, Rasha Khalid. "Chemical Constituents of the Goat Margarine and Antibacterial Activity against Bacterial Pathogens in Sudan." Journal of Pure and Applied Microbiology 13, no. 1 (March 31, 2019): 225–32. http://dx.doi.org/10.22207/jpam.13.1.23.

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31

Maggi, Maria Anna, Silvia Bisti, and Cristiana Picco. "Saffron: Chemical Composition and Neuroprotective Activity." Molecules 25, no. 23 (November 29, 2020): 5618. http://dx.doi.org/10.3390/molecules25235618.

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Crocus sativus L. belongs to the Iridaceae family and it is commonly known as saffron. The different cultures together with the geoclimatic characteristics of the territory determine a different chemical composition that characterizes the final product. This is why a complete knowledge of this product is fundamental, from which more than 150 chemical compounds have been extracted from, but only about one third of them have been identified. The chemical composition of saffron has been studied in relation to its efficacy in coping with neurodegenerative retinal diseases. Accordingly, experimental results provide evidence of a strict correlation between chemical composition and neuroprotective capacity. We found that saffron’s ability to cope with retinal neurodegeneration is related to: (1) the presence of specific crocins and (2) the contribution of other saffron components. We summarize previous evidence and provide original data showing that results obtained both “in vivo” and “in vitro” lead to the same conclusion.
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Radhakrishnan, Arun, and Harden M. McConnell. "Chemical Activity of Cholesterol in Membranes†." Biochemistry 39, no. 28 (July 2000): 8119–24. http://dx.doi.org/10.1021/bi0005097.

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McKinney, J. D. "Interactive hormonal activity of chemical mixtures." Environmental Health Perspectives 105, no. 9 (September 1997): 896–97. http://dx.doi.org/10.1289/ehp.97105896.

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34

Benigni, Romualdo. "Structure–Activity models for chemical carcinogens." Toxicology Letters 189 (September 2009): S6. http://dx.doi.org/10.1016/j.toxlet.2009.06.174.

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Karwath, Andreas, and Luc De Raedt. "SMIREP: Predicting Chemical Activity from SMILES." Journal of Chemical Information and Modeling 46, no. 6 (October 12, 2006): 2432–44. http://dx.doi.org/10.1021/ci060159g.

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36

Speers, Anna E., and Benjamin F. Cravatt. "Chemical Strategies for Activity-Based Proteomics." ChemBioChem 5, no. 1 (December 19, 2003): 41–47. http://dx.doi.org/10.1002/cbic.200300721.

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37

PAGE, M. I. "ChemInform Abstract: Structure-Activity Relationships: Chemical." ChemInform 25, no. 3 (August 19, 2010): no. http://dx.doi.org/10.1002/chin.199403284.

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38

Kaiser, J. "A Sideways Look at Chemical Activity." Science 265, no. 5181 (September 30, 1994): 2010. http://dx.doi.org/10.1126/science.265.5181.2010.

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ITO, Akira. "New Teaching Activity in Chemical Engineering." Journal of JSEE 56, no. 2 (2008): 63. http://dx.doi.org/10.4307/jsee.56.2_63.

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Hagenstein, Miriam C., and Norbert Sewald. "Chemical tools for activity-based proteomics." Journal of Biotechnology 124, no. 1 (June 2006): 56–73. http://dx.doi.org/10.1016/j.jbiotec.2005.12.005.

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Brack, André, and Bernard Barbier. "Chemical activity of simple basic peptides." Origins of Life and Evolution of the Biosphere 20, no. 2 (March 1990): 139–44. http://dx.doi.org/10.1007/bf01808274.

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Schoot, C. J., and K. H. Klaassens. "Plant growth activity and chemical structure." Recueil des Travaux Chimiques des Pays-Bas 75, no. 3 (September 2, 2010): 271–78. http://dx.doi.org/10.1002/recl.19560750306.

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Lieberman, Whitney K., Yihang Jing, and Jordan L. Meier. "Chemical control of multidomain acetyltransferase activity." Cell Chemical Biology 28, no. 4 (April 2021): 433–35. http://dx.doi.org/10.1016/j.chembiol.2021.03.015.

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44

Malankar, Hemant, S. S. Umare, and K. Singh. "Chemical composition and electrochemical activity of some chemically synthesized γ-MnO2." Journal of Applied Electrochemistry 40, no. 2 (September 3, 2009): 265–75. http://dx.doi.org/10.1007/s10800-009-9970-7.

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45

Vahid, Farhang, Amini Jahanshir, Javadi Taimoor, Nazemi Javad, and Ebadollahi Asgar. "Chemical Composition and Antifungal Activity of Essential Oil of Cymbopogoncitratus (DC.) Stapf. Against ThreePhytophthora Species." Greener Journal of Biological Sciences 3, no. 8 (October 14, 2013): 292–98. http://dx.doi.org/10.15580/gjbs.2013.8.240913861.

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46

Solovyova, N. V. "Quantum chemical modeling of antioxidant activity of glutathione interacting with hydroxyl- and superoxide anion radicals." Ukrainian Biochemical Journal 87, no. 2 (April 27, 2015): 156–62. http://dx.doi.org/10.15407/ubj87.02.156.

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47

Constani, Novena Risnalani Rintank, Hartati Soetjipto, and Sri Hartini. "Antibacterial Activity and Chemical Composition of Red Peacock Flower (Caesalpinia pulcherrima L.) Leaf Essential Oil." Jurnal Kimia Sains dan Aplikasi 22, no. 6 (October 4, 2019): 269–74. http://dx.doi.org/10.14710/jksa.22.6.269-274.

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Peacock flower (Caesalpinia pulcherrima L.) leaves contain essential oils which can be used as an ingredient in cosmetics, perfume, aromatherapy, medicine, and supplements. The study was conducted to obtain essential oils from peacock flower leaves and determine the antibacterial activity against gram-positive bacteria (Bacillus subtilis and Staphylococcus aureus) and gram-negative (Escherichia coli and Pseudomonas aeruginosa). Antibacterial activity test was carried out by the agar diffusion method, using paper discs. Measurements were made for the inhibition zone diameter (IZD) that appeared, while the essential oil component was analyzed using GC-MS. The results showed that the peacock flower leaves (C. pulcherrima) had a moderate to strong antibacterial effect at a concentration of 7.5%-20% against gram-positive bacteria (B. subtilis and S. aureus) and gram-negative bacteria (E. coli and P. aeruginosa). Gram-negative E. coli bacteria are relatively more sensitive to peacock flower leaf essential oil compared to other test bacteria. Peacock flower (C. pulcherrima) leaf essential oil is composed of 7 main components namely β-Cubebene 33.87%; Caryophyllene 23.00%; γ-Elemene 13.18%; α-Pinene 10.96%; Cadina-1(10),4-diene 10.20%; Copaene; 7.09%; β-Pinene 1.70%.
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Teles, Rogerio De Mesquita, Victor Elias Mouchrek Filho, and Antonio Gouveia De Souza. "Chemical Characterization and Larvicidal Activity of Essential Oil from Aniba duckei Kostermans against Aedes aegypti." International Journal of Life-Sciences Scientific Research 3, no. 6 (November 2017): 1495–99. http://dx.doi.org/10.21276/ijlssr.2017.3.6.11.

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Mutter, Fiona E., B. Kevin Park, and Ian M. Copple. "Value of monitoring Nrf2 activity for the detection of chemical and oxidative stress." Biochemical Society Transactions 43, no. 4 (August 1, 2015): 657–62. http://dx.doi.org/10.1042/bst20150044.

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Beyond specific limits of exposure, chemical entities can provoke deleterious effects in mammalian cells via direct interaction with critical macromolecules or by stimulating the accumulation of reactive oxygen species (ROS). In particular, these chemical and oxidative stresses can underpin adverse reactions to therapeutic drugs, which pose an unnecessary burden in the clinic and pharmaceutical industry. Novel pre-clinical testing strategies are required to identify, at an earlier stage in the development pathway, chemicals and drugs that are likely to provoke toxicity in humans. Mammalian cells can adapt to chemical and oxidative stress via the action of the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2), which up-regulates the expression of numerous cell defence genes and has been shown to protect against a variety of chemical toxicities. Here, we provide a brief overview of the Nrf2 pathway and summarize novel experimental models that can be used to monitor changes in Nrf2 pathway activity and thus understand the functional consequences of such perturbations in the context of chemical and drug toxicity. We also provide an outlook on the potential value of monitoring Nrf2 activity for improving the pre-clinical identification of chemicals and drugs with toxic liability in humans.
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Daglia, Maria, Maria Teresa Cuzzoni, and Cesare Dacarro. "Antibacterial activity of coffee: Relationship between biological activity and chemical markers." Journal of Agricultural and Food Chemistry 42, no. 10 (October 1994): 2273–77. http://dx.doi.org/10.1021/jf00046a036.

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