Log in

Relevant bibliographies by topics / CERNA NETWORK

Contents

Journal articles

Academic literature on the topic 'CERNA NETWORK'

Author: Grafiati

Published: 11 September 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'CERNA NETWORK.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "CERNA NETWORK"

1

Qi, Xin, Yuxin Lin, Jiajia Chen, and Bairong Shen. "Decoding competing endogenous RNA networks for cancer biomarker discovery." Briefings in Bioinformatics 21, no. 2 (2019): 441–57. http://dx.doi.org/10.1093/bib/bbz006.

Full text

Abstract:

Abstract Crosstalk between competing endogenous RNAs (ceRNAs) is mediated by shared microRNAs (miRNAs) and plays important roles both in normal physiology and tumorigenesis; thus, it is attractive for systems-level decoding of gene regulation. As ceRNA networks link the function of miRNAs with that of transcripts sharing the same miRNA response elements (MREs), e.g. pseudogenes, competing mRNAs, long non-coding RNAs, and circular RNAs, the perturbation of crucial interactions in ceRNA networks may contribute to carcinogenesis by affecting the balance of cellular regulatory system. Therefore, d

APA, Harvard, Vancouver, ISO, and other styles

2

Hsiao, Yi-Wen, Lin Wang, and Tzu-Pin Lu. "ceRNAR: An R package for identification and analysis of ceRNA-miRNA triplets." PLOS Computational Biology 18, no. 9 (2022): e1010497. http://dx.doi.org/10.1371/journal.pcbi.1010497.

Full text

Abstract:

Competitive endogenous RNA (ceRNA) represents a novel mechanism of gene regulation that controls several biological and pathological processes. Recently, an increasing number of in silico methods have been developed to accelerate the identification of such regulatory events. However, there is still a need for a tool supporting the hypothesis that ceRNA regulatory events only occur at specific miRNA expression levels. To this end, we present an R package, ceRNAR, which allows identification and analysis of ceRNA-miRNA triplets via integration of miRNA and RNA expression data. The ceRNAR package

APA, Harvard, Vancouver, ISO, and other styles

3

Jayarathna, Dulari K., Miguel E. Rentería, Emilie Sauret, Jyotsna Batra, and Neha S. Gandhi. "Identifying Complex lncRNA/Pseudogene–miRNA–mRNA Crosstalk in Hormone-Dependent Cancers." Biology 10, no. 10 (2021): 1014. http://dx.doi.org/10.3390/biology10101014.

Full text

Abstract:

The discovery of microRNAs (miRNAs) has fundamentally transformed our understanding of gene regulation. The competing endogenous RNA (ceRNA) hypothesis postulates that messenger RNAs and other RNA transcripts, such as long non-coding RNAs and pseudogenes, can act as natural miRNA sponges. These RNAs influence each other’s expression levels by competing for the same pool of miRNAs through miRNA response elements on their target transcripts, thereby modulating gene expression and protein activity. In recent years, these ceRNA regulatory networks have gained considerable attention in cancer resea

APA, Harvard, Vancouver, ISO, and other styles

4

Chen, Chen, Li Wang, Qiuju Feng, Qi Liu, Li Wang, and Shuming Huang. "Comprehensive Landscape of Modules-Dysregulated Functions Reveals a Profound Role of ceRNAs in Coronary Heart Disease." Journal of Healthcare Engineering 2022 (March 8, 2022): 1–10. http://dx.doi.org/10.1155/2022/4547413.

Full text

Abstract:

Coronary heart disease (CHD) is one of the most common severe cardiovascular diseases. Competitive endogenous RNAs (ceRNA) play critical roles in complex diseases. However, our understanding of the dysregulated functions of ceRNAs in CHD remains limited. Here, we systematically analyzed the alterations of ceRNAs and identified the specific functions based on dysregulated modules from the ceRNA network. A total of 2457 significantly differential expressed genes and 212 differential expressed lncRNAs were identified. We got 76679 regulator relationship between different expression genes and miRN

APA, Harvard, Vancouver, ISO, and other styles

5

Liang, Ying-Chun, Yu-Peng Wu, Dong-Ning Chen, et al. "Building a Competing Endogenous RNA Network to Find Potential Long Non-Coding RNA Biomarkers for Pheochromocytoma." Cellular Physiology and Biochemistry 51, no. 6 (2018): 2916–24. http://dx.doi.org/10.1159/000496043.

Full text

Abstract:

Background/Aims: Accumulating evidence has shown that long non-coding RNAs (lncRNAs) in competing endogenous RNA (ceRNA) networks play crucial roles in tumor survival and patient prognosis; however, studies investigating ceRNA networks in pheochromocytoma (PCC) are lacking. In this study, we investigated the pathogenesis of PCC and whether lncRNAs acting through ceRNAs networks were associated with prognosis. Methods: A total of 183 PCC samples and 3 control samples from The Cancer Genome Atlas database were analyzed. The Empirical Analysis of Digital Gene Expression Data package in R (edgeR)

APA, Harvard, Vancouver, ISO, and other styles

6

Ye, Hongwei, Yuping Li, Lu Li, Yuhui Huang, Jiahui Wang, and Qin Gao. "Construction of a ceRNA network of regulated ferroptosis in doxorubicin-induced myocardial injury." PeerJ 11 (January 25, 2023): e14767. http://dx.doi.org/10.7717/peerj.14767.

Full text

Abstract:

Background Ferroptosis and long-noncoding RNAs (lncRNAs) play crucial roles in doxorubicin (DOX)-induced myocardial injury (DIMI). Nevertheless, there is no research to construct competing endogenous RNAs (ceRNAs) network between lncRNAs and ferroptosis-related key gene. So our research was designed to screen ferroptosis-related genes from differentially expressed mRNAs in DIMI and construct lncRNAs regulated ferroptosis-related key gene ceRNAs network. Methods The male mice were injected with DOX intraperitoneally to induce myocardial injury, myocardial injury was evaluated by hematoxylin and

APA, Harvard, Vancouver, ISO, and other styles

7

Sheng, Han, Huan Pan, Ming Yao, et al. "Integrated Analysis of Circular RNA-Associated ceRNA Network Reveals Potential circRNA Biomarkers in Human Breast Cancer." Computational and Mathematical Methods in Medicine 2021 (December 20, 2021): 1–16. http://dx.doi.org/10.1155/2021/1732176.

Full text

Abstract:

Circular RNA (circRNA) is closely related to tumorigenesis and cancer progression. Yet, the roles of cancer-specific circRNAs in the circRNA-related ceRNA network of breast cancer (BRCA) remain unclear. The aim of this study was to construct a ceRNA network associated with circRNA and to explore new therapeutic and prognostic targets and biomarkers for breast cancer. We downloaded the circRNA expression profile of BRCA from Gene Expression Omnibus (GEO) microarray datasets and downloaded the miRNA and mRNA expression profiles of BRCA from The Cancer Genome Atlas (TCGA) database. Differentially

APA, Harvard, Vancouver, ISO, and other styles

8

Wang, Chao, Kunkai Su, Hanchao Lin, Beini Cen, Shusen Zheng, and Xiao Xu. "Identification and Verification of a Novel MAGI2-AS3/miRNA-374-5p/FOXO1 Network Associated with HBV-Related HCC." Cells 11, no. 21 (2022): 3466. http://dx.doi.org/10.3390/cells11213466.

Full text

Abstract:

Background: Hepatocellular carcinoma (HCC) is a very common neoplasm worldwide, and competitive endogenous RNA (ceRNA) plays an important role in the development of HCC. The purpose of this study is to investigate the molecular mechanisms of ceRNAs in HCC. Methods: This study detects potential ceRNAs from HCC through whole genome analysis of lncRNA, miRNA and mRNA expression. We then performed high-throughput sequencing of tissues from five hepatitis B related HCC patients to screen ceRNAs and those screened ceRNAs expressions were verified on tissues from an independent group of six patients.

APA, Harvard, Vancouver, ISO, and other styles

9

An, Biao, Yuan Hu, and Xiao Liang. "Integrated Analysis of the lncRNA-Associated ceRNA Network in Wilms Tumor via TARGET and GEO Databases." Genetics Research 2022 (August 31, 2022): 1–12. http://dx.doi.org/10.1155/2022/2365991.

Full text

Abstract:

Wilms tumor (WT) is the most common genitourinary renal tumor that typically occurs in children under 15 and is thought to be linked to somatic and germline mutations. However, the specific functional role of competing endogenous RNAs (ceRNAs) and their potential implications in WT remain unclear. In this study, we developed an lncRNA-mediated (long noncoding RNA-mediated) ceRNA network via the R packages for WT with expression data obtained from the tumor alterations relevant for genomics-driven therapy (TARGET) database. Unsupervised hierarchical clustering analysis revealed that the WT spec

APA, Harvard, Vancouver, ISO, and other styles

10

Ye, Junhong, Jifu Li, and Ping Zhao. "Roles of ncRNAs as ceRNAs in Gastric Cancer." Genes 12, no. 7 (2021): 1036. http://dx.doi.org/10.3390/genes12071036.

Full text

Abstract:

Although ignored in the past, with the recent deepening of research, significant progress has been made in the field of non-coding RNAs (ncRNAs). Accumulating evidence has revealed that microRNA (miRNA) response elements regulate RNA. Long ncRNAs, circular RNAs, pseudogenes, miRNAs, and messenger RNAs (mRNAs) form a competitive endogenous RNA (ceRNA) network that plays an essential role in cancer and cardiovascular, neurodegenerative, and autoimmune diseases. Gastric cancer (GC) is one of the most common cancers, with a high degree of malignancy. Considerable progress has been made in understa

APA, Harvard, Vancouver, ISO, and other styles

More sources

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!