Journal articles: 'Cerebrovascular disease – Diagnosis'

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Lee, Kwang Ho. "Diagnosis of Cerebrovascular Disease." Journal of the Korean Medical Association 45, no. 12 (2002): 1432. http://dx.doi.org/10.5124/jkma.2002.45.12.1432.

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Thomas, D. "Ultrasonic Diagnosis of Cerebrovascular Disease." Journal of Neurology, Neurosurgery & Psychiatry 51, no. 3 (March 1, 1988): 471. http://dx.doi.org/10.1136/jnnp.51.3.471.

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Shaikh, Arooj. "Ultrasound Diagnosis of Cerebrovascular Disease." Ultrasound Quarterly 12, no. 3 (1994): 185. http://dx.doi.org/10.1097/00013644-199412030-00003.

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Polonara, G., J. Bove, L. Regnicolo, N. Herber, E. Cesaroni, and N. Zamponi. "Paediatric Cerebrovascular Disease: Neuroradiological Diagnosis." Rivista di Neuroradiologia 18, no. 3 (June 2005): 304–14. http://dx.doi.org/10.1177/197140090501800306.

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The low incidence (2.6 cases in 100,000) of cerebrovascular disease in paediatric patients compared with the adult population makes it a diagnostic challenge. Etiological factors have changed over time: whereas in the past bacterial meningitis was the most frequent cause, heart disease, haematological disorders, vasculopathy and viral infections have now become the most common. Haemorrhagic stroke is most frequently due to arteriovenous malformations (AVMs), cavernous angioma, haematological disorders and intracranial aneurysms. Traumatic or fibrodyplastic arterial thrombosis is extremely rare. Venous thrombosis most commonly affects the upper sagittal sinus. In two thirds of cases the cause of stroke remains unknown. For years, symptoms of acute CNS deficits have been studied with computed tomography (CT), especially to rule out haemorrhage. To avoid exposing paediatric patients to ionizing radiation, magnetic resonance imaging (MRI), more sensitive and specific for the identification of acute ischaemic stroke, is currently the first-line diagnostic technique. In particular, diffusion-weighted sequences are capable of early identification of ischaemic areas. Association with perfusion techniques will define the areas at high risk of further damage and to attempt to estimate the final volume of the lesion. MR spectroscopy contributes to the characterization of ischaemic lesions. MR angiography (MRA) has proved to be a noninvasive technique with the same diagnostic effectiveness as conventional angiography for dissections, transient cerebral arteriopathy and moyamoya. The cervical arteries are studied using contrast-enhanced sequences. Conventional angiography remains the technique of choice for the study of small vessels disease and AVMs.

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Newmark, Harris. "Ultrasonic Diagnosis of Cerebrovascular Disease." Radiology 167, no. 1 (April 1988): 120. http://dx.doi.org/10.1148/radiology.167.1.120.

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Gewertz, Bruce L. "Extracrainal Cerebrovascular Disease: Diagnosis and Management." Annals of Vascular Surgery 1, no. 3 (November 1986): 396. http://dx.doi.org/10.1016/s0890-5096(06)60144-1.

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Cameron, H., W. Reid, K. G. Fowler, J. Wardlaw, and D. J. Stott. "Diagnosis of Multi-Infarct Cerebrovascular Disease." Age and Ageing 23, suppl 1 (January 1, 1994): P17. http://dx.doi.org/10.1093/ageing/23.suppl_1.p17-a.

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Lioutas, Vasileios-Arsenios, Shruti Sonni, and Louis R. Caplan. "Diagnosis and Misdiagnosis of Cerebrovascular Disease." Current Treatment Options in Cardiovascular Medicine 15, no. 3 (March 29, 2013): 276–87. http://dx.doi.org/10.1007/s11936-013-0233-x.

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Parfenov, V. A. "Ménière’s disease and chronic cerebrovascular diseases." Meditsinskiy sovet = Medical Council, no. 19 (December 1, 2021): 35–40. http://dx.doi.org/10.21518/2079-701x-2021-19-35-40.

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Ménière’s disease (MD) is an idiopathic inner ear disease, which is characterized by noise in the ears, periodic attacks of vertigo and the development of sensorineural hearing loss. MD is characterized by endolymphatic hydrops – an increase in the volume of endolymph that fills the membered labyrinth of the inner ear. Currently highlighted subtypes MD. The first subtype meets most often and is characterized by classical manifestations of MD. The second subtype is characterized by the development of sensorineural hearing loss, to which only after a long time are joined by the episodes of dizziness. The third subtype of MD includes family cases of the disease. The fourth and fifth subtypes of MD is observed in patients with migraine and autoimmune diseases. The diagnosis of definite MD is based on the 2 or more spontaneous episodes of vertigo with each lasting 20 minutes to 12 hours, low-to medium-frequency sensorineural hearing loss in one ear, fluctuating aural symptoms (fullness, hearing, tinnitus) located in the affected ear, and lack of data for other reasons for dizziness. There are no effective treatment for auditory disorders MD, therapy is aimed at preventing dizziness attacks. The first line of MD’s therapy includes a dietary salt restriction, the use of betahistine and diuretics. Betahistine (Betaserc) is usually used in a daily dose of 48 mg for 3–6 months to reduce the frequency of vertigo. For long-term treatment, it is convenient to use a betahistine modified-released (Betaserc Long) 48 mg, taken once a day. With the ineffectiveness of conservative therapy, other methods of therapy are possible: intratympanic administration of corticosteroids or gentamicin, labyrinthectomy or vestibular neurectomy. Unfortunately, many patients suffering from BM mistakenly makes a diagnosis of cerebrovascular disease, vertebrobasilar insufficiency, cervical osteochondrosis. Diagnostic errors are usually caused by the fact that the patients with MD are not conducted audiometry, vestibular tests, and the signs of cerebral microangiopathy identified when MRI brain are mistakenly regarded as confirmation of vascular dizziness genesis.

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Shchukin, I. A., A. V. Lebedeva, S. G. Burd, M. S. Fidler, R. K. Shikhkerimov, A. M. Ismailov, A. V. Bolotov, and M. Kh Belgusheva. "Chronic cerebrovascular disease: diagnosis and treatment questions." Consilium Medicum 18, no. 2 (2016): 85–94. http://dx.doi.org/10.26442/2075-1753_2016.2.85-94.

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Bullock, M. "Occlusive Cerebrovascular Disease: Diagnosis and Surgical Management." Journal of Neurology, Neurosurgery & Psychiatry 51, no. 9 (September 1, 1988): 1244–45. http://dx.doi.org/10.1136/jnnp.51.9.1244-b.

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Heros, Roberto C. "Occlusive Cerebrovascular Disease: Diagnosis and Surgical Management." Mayo Clinic Proceedings 62, no. 6 (June 1987): 531–32. http://dx.doi.org/10.1016/s0025-6196(12)65481-0.

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Clagett, G. Patrick. "Occlusive cerebrovascular disease: Diagnosis and surgical management." Journal of Vascular Surgery 6, no. 1 (July 1987): A1. http://dx.doi.org/10.1016/s0741-5214(87)70038-x.

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Caplan, Louis R., and Fong Kwong Sonny Hon. "Clinical diagnosis of patients with cerebrovascular disease." Primary Care: Clinics in Office Practice 31, no. 1 (March 2004): 95–109. http://dx.doi.org/10.1016/s0095-4543(03)00118-0.

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Patterson, Russel H. "Book ReviewExtracranial Cerebrovascular Disease: Diagnosis and management." New England Journal of Medicine 316, no. 14 (April 2, 1987): 885. http://dx.doi.org/10.1056/nejm198704023161424.

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Lee, K. Stuart. "Occlusive cerebrovascular disease—Diagnosis and surgical management." Surgical Neurology 30, no. 3 (September 1988): 253–54. http://dx.doi.org/10.1016/0090-3019(88)90289-3.

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Rothrock, John F., and Hans-Christoph Diener. "Headache secondary to cerebrovascular disease." Cephalalgia 41, no. 4 (March 18, 2021): 479–92. http://dx.doi.org/10.1177/0333102421999045.

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Objectives To discuss headache secondary to cerebrovascular disease. Background Headache is an important symptom in cerebrovascular diseases. In some conditions, headache is the leading symptom. Migraine is associated with an increased risk of stroke. Methods The authors undertook a literature search for the terms “headache” and “cerebrovascular diseases”. Results We report studies on headache in subarachnoidal hemorrhage, intracerebral hemorrhage, ischemic stroke, TIA, basilar artery thrombosis, cervical artery dissection, cerebellar stroke, arteritis and cerebral sinus venous thrombosis. In addition, we discuss migraine and stroke and thunderclap headache. Conclusions Headache is a leading symptom in many cerebrovascular diseases. Headache in combination with focal neurological deficits requires immediate diagnosis and treatment.

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Imai, Yutaka. "Progress in diagnosis of hypertension and cerebrovascular disease." Nosotchu 24, no. 4 (2002): 507–12. http://dx.doi.org/10.3995/jstroke.24.507.

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Ricci, Michael A. "Frontiers in Cerebrovascular Disease: Mechanisms, Diagnosis, and Treatment." Annals of Vascular Surgery 13, no. 3 (May 1999): 356. http://dx.doi.org/10.1016/s0890-5096(06)61779-2.

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Jellinger, K. A. "Frontiers in cerebrovascular disease. Mechanisms, diagnosis, and treatment." European Journal of Neurology 5, no. 3 (May 1998): 323–24. http://dx.doi.org/10.1046/j.1468-1331.1998.5303197.x.

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Heros, Roberto C. "Book ReviewOcclusive Cerebrovascular Disease: Diagnosis and surgical management." New England Journal of Medicine 316, no. 23 (June 4, 1987): 1483. http://dx.doi.org/10.1056/nejm198706043162320.

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Tegeler, Charles, and David Sherman. "Analytic Review: Ischemic Cerebrovascular Disease: Diagnosis and Management." Journal of Intensive Care Medicine 1, no. 4 (July 1986): 184–96. http://dx.doi.org/10.1177/088506668600100404.

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Ustrell-Roig, Xavier, and Joaquín Serena-Leal. "Stroke. Diagnosis and Therapeutic Management of Cerebrovascular Disease." Revista Española de Cardiología (English Edition) 60, no. 7 (January 2007): 753–69. http://dx.doi.org/10.1016/s1885-5857(08)60011-0.

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Wu, Chunyan, Xin Xu, and Rong Wang. "Application of CT Angiography in the Diagnosis of Acute Cerebrovascular Disease in Neurology." Journal of Medical Imaging and Health Informatics 11, no. 3 (March 1, 2021): 878–85. http://dx.doi.org/10.1166/jmihi.2021.3328.

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This article explores the application and value of CT angiography in the diagnosis of acute cerebrovascular disease in neurology. We selected 260 patients in our hospital as the research object, analyzed their data in detail, and then used the spiral CT scan to obtain the most original image. According to the projection technology with the strongest intensity and the scanned image, a three-dimensional image was formed on the surface. The images were studied and the results were compared with the results of postoperative and DSA techniques to finally evaluate the value of CTA technology in the diagnosis of cerebrovascular diseases. A retrospective analysis and study of angiographic results of 260 patients with ischemic cerebrovascular disease who underwent digital silhouette angiography (DSA). According to the age of patients, patients can be divided into three groups: young group, middle-aged group and elderly group, aged 18–45 years old, 45–60 years old, 60 years old or older. According to the classification of ischemic cerebrovascular disease, we can divide 260 patients into cerebral infarction group and transient ischemic attack group. The calculation of stenosis rate is based on the research methods of symptomatic carotid endarterectomy abroad. The rate of detection of stenoses in 8 patients with TIA was 87%, and the rate of detection in 30 patients with cerebral infarction was 96%. The rate of aneurysms detected in the diagnosis of SAH is 83%. The diagnosis of cerebrovascular disease in the etiology and treatment of CTA in neurology department has a statistically significant difference in the ratio of confirmed diagnosis and positive rate of protection (P >0.05). Finally, we conclude that CT angiography is widely used in the diagnosis of acute cerebrovascular disease in neurology, and its therapeutic effect is quite significant, which is worthy of promotion in clinical diagnosis and treatment.

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YAMANOUCHI, HIROSHI. "Asymptomatic cerebrovascular disorder. Diagnosis and countermeasures. Diagnosis and treatment of related diseases. Binswanger's disease." Nihon Naika Gakkai Zasshi 86, no. 5 (1997): 803–7. http://dx.doi.org/10.2169/naika.86.803.

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Albrecht, Katinka, Imke Redeker, Martin Aringer, Ursula Marschall, Anja Strangfeld, and Johanna Callhoff. "Comorbidity and healthcare utilisation in persons with incident systemic lupus erythematosus followed for 3 years after diagnosis: analysis of a claims data cohort." Lupus Science & Medicine 8, no. 1 (August 2021): e000526. http://dx.doi.org/10.1136/lupus-2021-000526.

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ObjectiveTo analyse comorbidity and healthcare utilisation in individuals with SLE.MethodsA cohort of individuals with incident SLE diagnosis in 2016 were investigated using claims data from a German statutory health insurance fund. Concomitant diagnoses, medical prescriptions, hospitalisation and sick leave were analysed in the year prior to diagnosis and during a 3-year follow-up in comparison with age-matched and sex-matched controls (1) without autoimmune diseases and (2) with incident diabetes mellitus. Sensitivity analyses were performed excluding cases with additional autoimmune diagnoses and without prescription of antimalarials.ResultsAmong 571 individuals with SLE, hypertension (48%), depression (30%), hyperlipidaemia (25%), osteoarthritis (25%) and osteoporosis (20%) were the most frequent comorbidities in 2016. Cerebrovascular disease was documented in 9.6%. The number of drugs (mean 9.6, ∆+6.2), hospitalisation (40%, ∆+27%) and days on sick leave (median 46 days, ∆+27 days) increased significantly in the first year with SLE diagnosis. Individuals with SLE were more frequently hospitalised and had more medications compared with both control groups (all p<0.001). The increase in comorbidity diagnoses was low in controls without autoimmune diseases, while controls with diabetes showed a more pronounced increase in cardiovascular risk factors, but less in osteoporosis and cerebrovascular disease. Sensitivity analyses showed comparable results.ConclusionComorbidities are frequently detected at the time of diagnosis of SLE. High numbers of drug prescriptions and hospitalisation following SLE diagnosis reflect the comprehensive disease burden. The comparison with incident diabetes shows that differences with controls without autoimmune disease are overestimated by detection bias.

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Musliner, K., T. Laursen, T. Munk-Olsen, X. Liu, P. Mortensen, P. Zandi, and W. Eaton. "Vascular Disease and Trajectories of Late-life Major Depressive Disorder in Secondary Psychiatric Care." European Psychiatry 41, S1 (April 2017): s242. http://dx.doi.org/10.1016/j.eurpsy.2017.02.014.

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ObjectivesTo examine 5 years trajectories of secondary-treated late-life major depressive disorder (MDD), and evaluate whether pre-existing cerebrovascular disease and related risk factors are associated with more severe trajectories of late-life MDD.MethodsData were obtained from Danish registers. The sample included 11,184 adults ≥ 60 at index MDD diagnosis. Trajectories of in or outpatient contact at psychiatric hospitals for MDD over the 5 years period following index MDD diagnosis were modeled using latent class growth analysis. Risk factors included cerebrovascular disease, cardiovascular disease, hypertension, diabetes, and vascular dementia defined based on hospital diagnoses and prescription medications, demographic characteristics and characteristics of the index MDD diagnosis.ResultsThe final model included classes with consistently low (66%), high decreasing (19%), consistently high (9%) and moderate fluctuating (6%) probabilities of contact at a psychiatric hospital for MDD during the 5 year period following the index MDD diagnosis (Fig. 1). Older age, greater severity, inpatient treatment and > 12 antidepressant prescriptions within 5 years of the index MDD diagnosis predicted membership in more severe trajectory classes. Cerebrovascular disease and related risk factors were not associated with trajectory class membership.ConclusionsA substantial proportion (34%) of individuals diagnosed with MDD in late-life require specialized psychiatric treatment for extended periods of time. We found no evidence that cerebrovascular disease or related risk factors predicted course trajectories in secondary-treated late-life MDD.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Phipps, Michael S., Ania M. Jastreboff, Karen Furie, and Walter N. Kernan. "The Diagnosis and Management of Cerebrovascular Disease in Diabetes." Current Diabetes Reports 12, no. 3 (April 11, 2012): 314–23. http://dx.doi.org/10.1007/s11892-012-0271-x.

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Archila, Ricardo, and Antonieta Mahfoud. "Cerebrovascular disease in children and adolescents: Diagnosis and treatment." Pediatric Neurology 8, no. 5 (September 1992): 397. http://dx.doi.org/10.1016/0887-8994(92)90296-b.

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Li, Yanjiao, Zhipeng Liu, Baojin Wu, Jingrui Zhang, and Chao Li. "Combined Application of CT Perfusion Imaging and CT Angiography in Imaging Diagnosis of Acute Cerebrovascular Diseases." Journal of Healthcare Engineering 2021 (October 29, 2021): 1–13. http://dx.doi.org/10.1155/2021/4825285.

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The incidence rate of cerebrovascular diseases is increasing year by year, but the accuracy of clinical diagnosis is not high enough to cause disease. Many patients cannot effectively diagnose and treat the disease at the early stage. CT perfusion imaging (CTP) and CT angiography (CTA) were used to diagnose cerebrovascular diseases. In this paper, 26 cases of patients with acute cerebrovascular disease in our hospital from June to August 2020 were selected as the research objects. According to the diagnosis method voluntarily chosen by patients, 6 cases were only detected by CT perfusion imaging, 8 cases were only detected by CT angiography, and the remaining 12 cases were diagnosed by CT perfusion imaging and CT angiography. Then, according to the diagnosis results of the CT image of the patients with cerebrovascular disease, these samples were followed up after 3 months, 6 months, and 9 months, and more accurate diagnosis results were obtained. The study showed that, after 3 months of CT detection, the sensitivity of patients with CTP detection was 67%, that of patients with CTA detection was 72%, and that of patients with combined detection was 83%. After 6 months of CT detection, the sensitivity of patients with CTP detection was 75%, that of patients with CTA detection was 79%, and that of patients with combined detection was 93%. After 9 months of CT detection, the sensitivity of patients with CTP detection was 86%, that of patients with CTA detection was 89%, and that of patients with combined detection was 99%. Therefore, the use of CTA combined with CTP joint detection of acute cerebrovascular disease imaging technology can effectively improve the diagnostic accuracy of patients.

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Zhu, Qin, Die Luo, Xiaojun Zhou, Xianxu Cai, Qi Li, Yuanan Lu, and Jiayan Chen. "A Model for Risk Prediction of Cerebrovascular Disease Prevalence—Based on Community Residents Aged 40 and above in a City in China." International Journal of Environmental Research and Public Health 18, no. 12 (June 18, 2021): 6584. http://dx.doi.org/10.3390/ijerph18126584.

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Cerebrovascular disease (CVD) is the leading cause of death in many countries including China. Early diagnosis and risk assessment represent one of effective approaches to reduce the CVD-related mortality. The purpose of this study was to understand the prevalence and influencing factors of cerebrovascular disease among community residents in Qingyunpu District, Nanchang City, Jiangxi Province, and to construct a model of cerebrovascular disease risk index suitable for local community residents. A stratified cluster sampling method was used to sample 2147 community residents aged 40 and above, and the prevalence of cerebrovascular diseases and possible risk factors were investigated. It was found that the prevalence of cerebrovascular disease among local residents was 4.5%. Poisson regression analysis found that old age, lack of exercise, hypertension, diabetes, smoking, and family history of cerebrovascular disease are the main risk factors for local cerebrovascular disease. The relative risk ORs were 3.284, 2.306, 2.510, 3.194, 1.949, 2.315, respectively. For these six selected risk factors, a cerebrovascular disease risk prediction model was established using the Harvard Cancer Index method. The R value of the risk prediction model was 1.80 (sensitivity 81.8%, specificity 47.0%), which was able to well predict the risk of cerebrovascular disease among local residents. This provides a scientific basis for the further development of local cerebrovascular disease prevention and control work.

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Lin, Chien-Heng, Jung-Nien Lai, Inn-Chi Lee, I.-Ching Chou, Wei-De Lin, Mei-Chen Lin, and Syuan-Yu Hong. "Kawasaki Disease May Increase the Risk of Subsequent Cerebrovascular Disease." Stroke 53, no. 4 (April 2022): 1256–62. http://dx.doi.org/10.1161/strokeaha.120.032953.

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Background: Previous epidemiological investigations examining the association between Kawasaki disease (KD) and cerebrovascular disease have had conflicting results. We analyzed the association between KD and cerebrovascular disease by conducting a population-based retrospective cohort study designed to investigate the hypothesis that KD could be a risk factor for subsequent cerebrovascular disease. Methods: From the National Health Insurance Research Database of Taiwan, the data of children (aged 0–18 years old) with KD (n=8467) were collected. Starting with the first year of study observation (referred to as the baseline year), data was collected for each child with KD, and 4 non-KD patients matched for sex, urbanization level of residence, and parental occupation were randomly selected to form the non-KD cohort (n=33 868) for our analysis. For the period from January 1, 2000, to December 31, 2012, we calculated the follow-up person-years for each patient, which is the time from the index date to the diagnosis of cerebrovascular disease, death, or the end of 2012. Furthermore, we compared the incidence, the incidence rate ratio, and the 95% CI of cerebrovascular disease between the KD and non-KD cohorts. Results: The overall cerebrovascular disease incidence rate was found to be 3.19-fold higher, which is significantly higher, in the KD cohort than in the non-KD cohort (14.73 versus 4.62 per 100 000 person-years), and the overall risk of cerebrovascular disease remained higher in the KD cohort (adjusted hazard ratio, 3.16 [95% CI, 1.46–6.85]). Furthermore, children aged <5 years showed a significantly higher risk of subsequent cerebrovascular disease in the KD cohort (adjusted hazard ratio, 3.14 [95% CI, 1.43–6.92]). Conclusions: This nationwide retrospective cohort study shows that KD may increase the risk of subsequent cerebrovascular disease, especially in those with KD aged <5 years old.

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Fan, Mingqiang, Xiangxiang Yang, Tao Ding, Yu Cao, Qiaoke Si, Jing Bai, Yongchun Lin, and Xinke Zhao. "Application of Ultrasound Virtual Reality in the Diagnosis and Treatment of Cardiovascular Diseases." Journal of Healthcare Engineering 2021 (August 17, 2021): 1–10. http://dx.doi.org/10.1155/2021/9999654.

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Cardiovascular disease is a common chronic disease in the medical field, which has a great impact on the health of Chinese residents (especially the elderly). At present, the effectiveness of the prevention and treatment of cardiovascular diseases in my country is not optimistic. Overall, the prevalence and mortality of CVD are still on the rise. The timely and effective detection and treatment of cardiovascular and cerebrovascular diseases are of great practical significance to improve the health of residents and to carry out prevention and treatment. This article aims to study the application of ultrasound-based virtual reality technology in the diagnosis and treatment of cardiovascular diseases to improve the efficiency and accuracy of the diagnosis of cardiovascular and cerebrovascular diseases by medical staff. The focus is on the application of feature attribute selection related algorithms and classification related algorithms in medical and health diagnosis systems, and a cardiovascular and cerebrovascular disease diagnosis system based on naive Bayes algorithm and improved genetic algorithm is designed and developed. The system builds a diagnostic model for cardiovascular and cerebrovascular diseases and diagnoses and displays the corresponding results based on the patient’s examination data. This paper first puts forward the theoretical concepts of ultrasonic virtual reality technology, scientific computing visualization, genetic algorithm, naive Bayes algorithm, and surgery simulation system and describes them in detail. Then, we construct a three-dimensional ultrasonic virtual measurement system, from the collection and reconstruction of image data to the filtering and segmentation of image data, plus the application of three-dimensional visualization and virtual reality technology to construct a three-dimensional measurement system. The experimental results in this paper show that 10 isolated congenital heart disease models with atrial septal defect (ASD) established through the use of three-dimensional visualization and virtual reality technology measured the short diameter, long diameter, and area of the atrial septal defect in the left and right atria. Finally, a value of L less than 0.05 indicates that the statistics are meaningful, and a value of r generally greater than 0.9 indicates that the virtual measurement result is highly correlated with the real measurement result.

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Li, Meng, and Junping Zhang. "Circulating MicroRNAs: Potential and Emerging Biomarkers for Diagnosis of Cardiovascular and Cerebrovascular Diseases." BioMed Research International 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/730535.

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MicroRNAs (miRNAs) are composed of a group of endogenous and noncoding small RNAs which control expression of complementary target mRNAs. The extended functions of miRNAs enhance the complexity of gene-regulatory processes in cardiovascular and cerebrovascular diseases. Indeed, recent studies have shown that miRNAs are closely related to myocardial infarction, heart failure, atrial fibrillation, cardiomyopathy, hypertension, angiogenesis, coronary artery disease, dyslipidaemia, stroke, and so forth. These findings suggest a new therapeutic pointcut for cardiovascular and cerebrovascular diseases and show the extensive therapeutic potential of miRNA regulation. Moreover, it has been shown that circulating extracellular miRNAs are stable in bodily fluids, which indicates circulating miRNAs as potential and emerging biomarkers for noninvasive diagnosis. This review highlights the most recent findings indicative of circulating miRNAs as potential clinical biomarkers for diagnosis of cardiovascular and cerebrovascular diseases.

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Xia, Ying, Nawaf Yassi, Parnesh Raniga, Pierrick Bourgeat, Patricia Desmond, James Doecke, David Ames, et al. "Comorbidity of Cerebrovascular and Alzheimer’s Disease in Aging." Journal of Alzheimer's Disease 78, no. 1 (October 27, 2020): 321–34. http://dx.doi.org/10.3233/jad-200419.

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Background: Cerebrovascular disease often coexists with Alzheimer’s disease (AD). While both diseases share common risk factors, their interrelationship remains unclear. Increasing the understanding of how cerebrovascular changes interact with AD is essential to develop therapeutic strategies and refine biomarkers for early diagnosis. Objective: We investigate the prevalence and risk factors for the comorbidity of amyloid-β (Aβ) and cerebrovascular disease in the Australian Imaging, Biomarkers and Lifestyle Study of Ageing, and further examine their cross-sectional association. Methods: A total of 598 participants (422 cognitively normal, 89 with mild cognitive impairment, 87 with AD) underwent positron emission tomography and structural magnetic resonance imaging for assessment of Aβ deposition and cerebrovascular disease. Individuals were categorized based on the comorbidity status of Aβ and cerebrovascular disease (V) as Aβ–V–, Aβ–V+, Aβ+V–, or Aβ+V+. Results: Advancing age was associated with greater likelihood of cerebrovascular disease, high Aβ load and their comorbidity. Apolipoprotein E ɛ4 carriage was only associated with Aβ positivity. Greater total and regional WMH burden were observed in participants with AD. However, no association were observed between Aβ and WMH measures after stratification by clinical classification, suggesting that the observed association between AD and cerebrovascular disease was driven by the common risk factor of age. Conclusion: Our observations demonstrate common comorbid condition of Aβ and cerebrovascular disease in later life. While our study did not demonstrate a convincing cross-sectional association between Aβ and WMH burden, future longitudinal studies are required to further confirm this.

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Young, Christopher C., Robert H. Bonow, Guilherme Barros, Mahmud Mossa-Basha, Louis J. Kim, and Michael R. Levitt. "Magnetic resonance vessel wall imaging in cerebrovascular diseases." Neurosurgical Focus 47, no. 6 (December 2019): E4. http://dx.doi.org/10.3171/2019.9.focus19599.

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Cerebrovascular diseases manifest as abnormalities of and disruption to the intracranial vasculature and its capacity to carry blood to the brain. However, the pathogenesis of many cerebrovascular diseases begins in the vessel wall. Traditional luminal and perfusion imaging techniques do not provide adequate information regarding the differentiation, onset, or progression of disease. Intracranial high-resolution MR vessel wall imaging (VWI) has emerged as an invaluable technique for understanding and evaluating cerebrovascular diseases. The location and pattern of contrast enhancement in intracranial VWI provides new insight into the inflammatory etiology of cerebrovascular diseases and has potential to permit earlier diagnosis and treatment. In this report, technical considerations of VWI are discussed and current applications of VWI in vascular malformations, blunt cerebrovascular injury/dissection, and steno-occlusive cerebrovascular vasculopathies are reviewed.

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Antonenko, L. M., N. V. Vakhnina, and D. O. Gromova. "Cognitive impairment, dizziness, and unsteadiness in hypertensive patients." Neurology, Neuropsychiatry, Psychosomatics 12, no. 5 (October 25, 2020): 92–97. http://dx.doi.org/10.14412/2074-2711-2020-5-92-97.

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Hypertension is a widespread disease related to modifiable vascular risk factors for stroke and chronic cerebrovascular diseases. The pathogenetic basis of brain damage in hypertension is cerebral microangiopathy that leads to vascular cognitive impairment (CI), instability, and falls. Microcirculatory changes in the presence of hypertension at the initial stages of cerebrovascular disease occur without visible clinical manifestations of brain damage. Pathogenetically justified treatment used at an early stage of the disease makes it possible to achieve good results in the prevention of vascular brain damage. An important aspect of selecting effective therapy is the competent diagnosis of the causes of dizziness and instability, which can be caused not only by brain damage, but also by peripheral vestibular system diseases. Early diagnosis of vascular CI, selection of adequate therapy, and prevention of their further progression are of great importance. The studies performed have shown the high efficacy of vinpocetine (Cavinton®) that has a multifactorial mechanism of action in the treatment and prevention of CI, dizziness, and instability caused by cerebrovascular disease.

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Mistiukevich, D. P. "DEMENTIA OF VASCULAR GENESIS: ETIOPATHOGENESIS, CLINICAL FEATURES, DIAGNOSIS, MANAGEMENT." Health and Ecology Issues, no. 2 (June 28, 2012): 27–34. http://dx.doi.org/10.51523/2708-6011.2012-9-2-5.

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Vascular dementia is the second most prevalent form of dementia after Alzheimer's disease and is characterized by the deficit of cognitive functions of cerebrovascular origin. At present, there are still opposing views about terminology, classification and diagnostic criteria, methods of treatment for vascular dementia. The aim of the preventive measures is to reduce vascular dementia prevalence by cerebrovascular disease effect on risk factors (primary prophylaxis), or treating patients after stroke (secondary prevention). The basic management of vascular dementia patients is based on the prescription of cholinesterase inhibitors.

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Chakor, Rahul T., and Nishikant Eklare. "Vertigo in Cerebrovascular Diseases." An International Journal of Otorhinolaryngology Clinics 4, no. 1 (2012): 46–53. http://dx.doi.org/10.5005/jp-journals-10003-1087.

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ABSTRACT Background Vertigo as a symptom of cerebrovascular disease is relatively uncommon. All types of cerebrovascular diseases namely ischemia, infarction, hemorrhage can produce vertigo. Since, cerebrovascular disease is an emergency prompt recognition and treatment is necessary to prevent neurologic deficit and death. Among cerebrovascular diseases vertebrobasilar territory strokes commonly present with vertigo. Since, the term vertigo is used nonspecifically by patients this may lead to delay in diagnosis of these strokes. This article reviews the epidemiology of vertigo in cerebrovascular diseases and the various stroke syndromes associated with vertigo. Summary Cerebrovascular diseases in the vertebrobasilar territory have vertigo, imbalance, dizziness in addition to other symptoms and signs. Posterior inferior cerebellar artery, anterior inferior cerebellar artery, superior cerebellar artery and basilar artery territory strokes can present with true vertigo. A high index of suspicion of stroke in patients with vertigo and risk factors for stroke is essential. Other vascular causes of vertigo are small cerebellar hemorrhage, vestibular cortex stroke, rotational vertebral artery syndrome, transverse/sigmoid sinus thrombosis and vestibular paroxysmia. Conclusion Cerebrovascular disorders are estimated to account for 3 to 4% of patients with vertigo or dizziness. Early detection and treatment is necessary to prevent disability and death in these cases of vascular vertigo. How to cite this article Chakor RT, Eklare N. Vertigo in Cerebrovascular diseases. Int J Otorhinolaryngol Clin 2012;4(1):46-53.

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Agaeva, Z. A. "ULTRASONIC DIAGNOSIS OF CEREBROVASCULAR DISEASE IN THE ASPHYXIA OF NEWBORN." Kubanskij nauchnyj medicinskij vestnik, no. 4 (January 1, 2017): 7–12. http://dx.doi.org/10.25207/1608-6228-2017-24-4-7-12.

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Elesber, Ahmad A., Piero O. Bonetti, and Amir Lerman. "Endothelial function and cerebrovascular disease: Implications for diagnosis and treatment." Current Treatment Options in Cardiovascular Medicine 8, no. 3 (May 2006): 213–19. http://dx.doi.org/10.1007/s11936-006-0014-x.

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Aminoff, M. J. "Cerebrovascular Disease: Pathophysiology, Diagnosis, and Management, vols 1 and 2,." JAMA: The Journal of the American Medical Association 280, no. 24 (December 23, 1998): 2129. http://dx.doi.org/10.1001/jama.280.24.2129.

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Rodrigue, Karen M. "Contribution of Cerebrovascular Health to the Diagnosis of Alzheimer Disease." JAMA Neurology 70, no. 4 (April 1, 2013): 438. http://dx.doi.org/10.1001/jamaneurol.2013.1862.

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Ramasubbu, Rajamannar, and Sidney H. Kennedy. "Factors Complicating the Diagnosis of Depression in Cerebrovascular Disease, Part I — Phenomenological and Nosological Issues*." Canadian Journal of Psychiatry 39, no. 10 (December 1994): 596–600. http://dx.doi.org/10.1177/070674379403901003.

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Depression is frequently associated with cerebrovascular disease. Early detection and intervention in depression may enhance rehabilitation potential. Difficulties encountered by clinicians in identifying depression in patients with cerebrovascular disease are numerous. This two part review focuses on issues related to the diagnosis of depression with emphasis on recognition of depressive symptoms and their relevance to the diagnosis of depressive syndromes in the presence of vascular lesions and associated neurological deficits. Furthermore, the value of diagnostic instruments and biological markers in identifying depression following stroke has been critically evaluated. In this first part of this two part paper, phenomenological and nosological aspects are considered with an emphasis on symptom profile, significance of vegetative symptoms and other related emotional responses such as catastrophic reaction, emotionalism and apathy in the diagnosis of depression following stroke. The applicability of diagnostic subcategories to define depressive syndromes associated with cerebrovascular disease and its clinical relevance is also discussed. The authors stress that knowledge on phenomenology of depression and other emotional responses related to cerebrovascular disease will facilitate better understanding of its clinical presentation and may improve diagnostic acumen.

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Kühne Escolà, Jordi, Simon Nagel, Christina Verez Sola, Eva Doroszewski, Hannah Jaschonek, Alexander Gutschalk, Christoph Gumbinger, and Jan C. Purrucker. "Diagnostic Accuracy in Teleneurological Stroke Consultations." Journal of Clinical Medicine 10, no. 6 (March 11, 2021): 1170. http://dx.doi.org/10.3390/jcm10061170.

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Background: The accuracy of diagnosing acute cerebrovascular disease via a teleneurology service and the characteristics of misdiagnosed patients are insufficiently known. Methods: A random sample (n = 1500) of all teleneurological consultations conducted between July 2015 and December 2017 was screened. Teleneurological diagnosis and hospital discharge diagnosis were compared. Diagnoses were then grouped into two main categories: cerebrovascular disease (CVD) and noncerebrovascular disease. Test characteristics were calculated. Results: Out of 1078 consultations, 52% (n = 561) had a final diagnosis of CVD. Patients with CVD could be accurately identified via teleneurological consultation (sensitivity 95.2%, 95% CI 93.2–96.8), but we observed a tendency towards false-positive diagnosis (specificity 77.4%, 95% CI 73.6–80.8). Characteristics of patients with a false-negative CVD diagnosis were similar to those of patients with a true-positive diagnosis, but patients with a false-negative CVD diagnosis had ischemic heart disease less frequently. In retrospect, one patient would have been considered a candidate for intravenous thrombolysis (0.2%). Conclusions: Teleneurological consultations are accurate for identifying patients with CVD, and there is a very low rate of missed candidates for thrombolysis. Apart from a lower prevalence of ischemic heart disease, characteristics of “stroke chameleons” were similar to those of correctly identified CVD patients.

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Pokharel, Babu Ram, P. Pant, R. Gurung, R. Koju, TRS Bedi, and M. Pathak. "Study of Cerebrovascular Disease at Dhulikhel Hospital." Nepalese Heart Journal 7, no. 1 (August 25, 2013): 40–43. http://dx.doi.org/10.3126/njh.v7i1.8501.

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A stroke is the rapidly developing loss of brain function due to disturbance in the blood supply to the brain. It is a medical emergency that requires rapid diagnosis and treatment. The availability of CT Scan has made it easier for early diagnosis and intervention. The aim of this study was to identify the risk factors (eg. hypertension, diabetes mellitus and cigarette smoking) commonly seen in patients admitted in the hospital with stroke along with age group, sex distribution, duration of stay in the hospital and the occupancy of stroke patients admitted in medical ward. A total of 51 stroke patient were admitted in medical ward in the review period. CT scan was used to differentiate hemorrhagic from ischemic stroke. Patients were analyzed in terms of risk factors (like hypertension, diabetes mellitus and cigarette smoking) along with age and sex. In case of ischemic stroke along with CT Scan, ECG, Echocardiography, Carotid Doppler was done accordingly. Out of 2307 total admissions in medical ward, 51 cases (2.2%) were stroke patients. Among the stroke cases, 59% constituted male and 41% female. Similarly around 25% of the total cases were Diabetic / Hypertensive both or alone, 35% of the total cases were smokers, 48.6% of the cases were in the 51-70 age groups. 61% stayed in the hospital for 5 days or less. Cerebrovascular disease carries a lot of financial, physical, social and emotional implications. If we can address the modifiable risk factors, we can reduce the incidence of stroke. Nepalese Heart Journal | Volume 7 | No.1 | November 2010 (special issue) | Page 40-43 DOI: http://dx.doi.org/10.3126/njh.v7i1.8501

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Stewart, Robert. "Vascular dementia: A diagnosis running out of time." British Journal of Psychiatry 180, no. 2 (February 2002): 152–56. http://dx.doi.org/10.1192/bjp.180.2.152.

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BackgroundThe concept of vascular dementia has a long history but its usefulness as a diagnostic category has been called into question.AimsTo evaluate vascular disease as a risk factor for dementia and the interface between cerebrovascular pathology and Alzheimer's disease.MethodThe literature on this topic was selectively reviewed and synthesised.ResultsRisk factors for cerebrovascular disease are also risk factors for dementia. However, the course of dementia, once it has developed, appears to be frequently determined by Alzheimer's disease.ConclusionsAs a public health measure, modification of vascular risk represents a potentially powerful means to prevent dementia through delaying its onset. However, an effect on progression of dementia, once it has developed, has yet to be established. The traditional view of vascular dementia and Alzheimer's disease as distinguishable conditions is becoming steadily less tenable.

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Raskurazhev, A. A., P. I. Kuznetsova, and M. M. Tanashyan. "Cerebrovascular manifestations of familial Mediterranean fever." Russian neurological journal 27, no. 2 (May 14, 2022): 70–75. http://dx.doi.org/10.30629/2658-7947-2022-27-2-70-75.

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This article provides an overview of modern concepts of cerebrovascular manifestations of familial Mediterranean fever (FMV), also known as periodic disease, and describes own clinical observation. Despite the relative infrequency of cerebrovascular accidents in the structure of the clinical phenomenology of FMV, common pathogenetic aspects of these diseases indicate the need for a detailed examination of patients with suspected FMV. In addition, insufficient awareness of physicians about autoinflammatory diseases (of which FMV is a prominent member) underlines the need to include FMV in the spectrum of differential diagnosis of ischemic stroke, including taking into account national characteristics.

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Parfenov, V. A., S. A. Zhivolupov, V. V. Zakharov, L. A. Belova, O. V. Lagoda, R. G. Esin, N. V. Vakhnina, and I. N. Samartsev. "Chronic cerebrovascular diseases: use of vinpocetine in neurological practice (Round Table proceedings)." Neurology, Neuropsychiatry, Psychosomatics 10, no. 4 (December 15, 2018): 139–45. http://dx.doi.org/10.14412/2074-2711-2018-4-139-145.

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The paper presents the proceedings of the Round Table with the participation of leading neurologists, which is devoted to chronic cerebrovascular diseases. It is noted that chronic cerebral ischemia (CCI), or dyscirculatory encephalopathy (DEP), is one of the most common neurological diagnoses in our country. The pathogenesis, clinical presentations, diagnosis and treatment of CCI (DEP) and its matching with vascular cognitive impairment (CI), which is regarded in foreign literature as the main manifestation of chronic cerebrovascular disease (CVD) were considered. The authors analyze clinical trials evaluating the efficacy of vinpocetine (Cavinton) in chronic CVD, dizziness, CI, as well as the use of new vinpocetine formulations, such as Cavinton Comforte, in various neurological diseases, dysphagia in particular, in poststroke patients.

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Tekin, Selma, Çağatay Hilmi Öncel, Mehmet Bülent Özdemir, Yalın Tolga Yaylalı, Işık Tekin, Özcan Güneş, Simin Rota, and Nuriye Kurbetli. "Relationship Between N-Terminal Probrain Natriuretic Peptide (NT-Pro BNP) Level, Infarct Type and Infarct Volume in Ischemic Cerebrovascular Disease." Journal of Stroke Medicine 3, no. 2 (October 19, 2020): 100–105. http://dx.doi.org/10.1177/2516608520938552.

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Background: N-terminal probrain natriuretic peptide, which is a neurohormone produced mainly by the heart, is increased in acute ischemic cerebrovascular disease. Here we aimed to investigate the relationship of N-terminal probrain natriuretic peptide levels with cerebrovascular disease subtypes, infarct volume, and prognosis in cerebrovascular disease, and to determine if N-terminal probrain natriuretic peptide could be a biomarker for ischemic cerebrovascular disease. Methods: Consecutive 105 patients with a diagnosis of acute ischemic cerebrovascular disease and 50 healthy controls were examined for serum N-terminal probrain natriuretic peptide concentration, cerebrovascular disease subtypes, infarct volumes, and clinical outcomes with the National Institute of Health Stroke Scale assessment. Results: Mean N-terminal probrain natriuretic peptide values of cardioembolic group were significantly higher than lacunar infarct group ( P < .005) and transient ischemic attack group ( P = .005). There was a relation between worsening in the National Institute of Health Stroke Scale and elevation at N-terminal probrain natriuretic peptide ( P = .001). However, between N-terminal probrain natriuretic peptide levels and infarct volume, significant correlation was not detected ( P = .44). Conclusion: N-terminal probrain natriuretic peptide can be used as a valuable marker to distinguish between cardioembolic infarct and lacunar infarct. In addition, N-terminal probrain natriuretic peptide levels might be used as a biomarker for differential diagnosis of transient ischemic attack group and to provide insight into the prognosis.

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Journal articles on the topic 'Cerebrovascular disease – Diagnosis'

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