Relevant bibliographies by topics / Cephalosporins

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Cephalosporins'

Author: Grafiati
Published: 4 June 2021
Last updated: 6 September 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Cephalosporins.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Cephalosporins"

1

Shahbaz, Kiran. "Cephalosporins: pharmacology and chemistry." Pharmaceutical and Biological Evaluations 4, no. 6 (December 3, 2017): 234. http://dx.doi.org/10.26510/2394-0859.pbe.2017.36.

Full text
Abstract:
Cephalosporins are the most important antibiotics having β-lactam ring and are obtained from a fungus Acremonium, also known as cephalosporium. The wide use of cephalosporins against bacteria in various severe infections such as respiratory tract infection (RTI), skin infection and urinary tract infection (UTI) has led the scientist dive into the detail of this antibacterial drug. The knowledge about structural activity relationship (SAR), spectrum of inhibition (SOI), chemical properties and pharmacology of cephalosporin has pivotal impact to device advanced therapeutic results. The treatment of a disease using cephalosporin has many pros and cons. If the pharmacology and chemical properties of this drug are known properly, many side effects can be diminished or minimized to a certain level. This article review some pharmacological and chemical properties of cephalosporins.
APA, Harvard, Vancouver, ISO, and other styles
2

Aiswarya P. Nath, Arul Balasubramanian, and Kothai Ramalingam. "Cephalosporins : An imperative antibiotic over the generations." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (January 20, 2020): 623–29. http://dx.doi.org/10.26452/ijrps.v11i1.1866.

Full text
Abstract:
Cephalosporins are the most commonly prescribed class of antibiotics, and its structure and pharmacology are similar to that of penicillin. It's a bactericidal, and its structure contains beta-lactam ring, as like of penicillin, which intervenes in bacterial cell wall synthesis. Cephalosporins are derived from the mold Acremonium (previously called as Cephalosporium). It was first discovered in 1945; scientists have been improving the structure of cephalosporins to make it more effective against a wider range of bacteria. Whenever the structure of cephalosporins modified, a new "generation" of cephalosporins are made. So far, there are five generations of cephalosporins available. They are prescribed against various organisms and infections. The cephalosporin antibiotics interfere with cell-wall synthesis of bacteria, leading to the breakdown of the infectious organism. To achieve this effect, the antibiotic must cross the bacterial cell wall and bind to the penicillin-binding proteins. Various generations of cephalosporins, mechanisms of resistance, pharmacokinetics, adverse reactions, and their clinical use were reviewed in this article. Most of the cephalosporins are available as parenteral, but the oral formulations are also available for certain drugs. Rather than learn all cephalosporins, it is reasonable for the clinician to be familiar with selected cephalosporins among the parenteral and oral formulations.
APA, Harvard, Vancouver, ISO, and other styles
3

Karadurmus, Leyla, Kaan Eşme, Nurgul K. Bakirhan, and Sibel A. Ozkan. "Recent Electrochemical Assays on Cephalosporins." Current Pharmaceutical Analysis 16, no. 4 (April 27, 2020): 337–49. http://dx.doi.org/10.2174/1573412915666190523120431.

Full text
Abstract:
: Antibiotics are an important class among drugs because they are a significant agent to deal with infections. Cephalosporins are a very important group of antibiotics in the β-lactam class. The cephalosporins are semisynthetic antibiotics derived from products of the fungus Cephalosporium. Cephalosporins are classified as first, second, third, fourth, and advanced generation, based largely on their antibacterial spectrum and stability to β-lactamases. Electrochemical methods have been used for the determination of cephalosporin just as used in the determination of many antibiotic drugs. Electroanalytical methods present generally high sensitivity, low cost, low requirements, ease of preparation of the samples in a very short time, and a short analysis time. The most commonly used types are cyclic voltammetry, differential pulse voltammetry, square wave voltammetry and linear sweep voltammetry. The aim of this review is to evaluate the advantages and uses of electroanalytical methods used in the determination of cephalosporins. In addition, current applications of the methods to the pharmaceutical analysis of cephalosporins will also be summarized in a table.
APA, Harvard, Vancouver, ISO, and other styles
4

Chaudhry, Saira B., Michael P. Veve, and Jamie L. Wagner. "Cephalosporins: A Focus on Side Chains and β-Lactam Cross-Reactivity." Pharmacy 7, no. 3 (July 29, 2019): 103. http://dx.doi.org/10.3390/pharmacy7030103.

Full text
Abstract:
Cephalosporins are among the most commonly prescribed antibiotic classes due to their wide clinical utility and general tolerability, with approximately 1–3% of the population reporting a cephalosporin allergy. However, clinicians may avoid the use of cephalosporins in patients with reported penicillin allergies despite the low potential for cross-reactivity. The misdiagnosis of β-lactam allergies and misunderstanding of cross-reactivity among β-lactams, including within the cephalosporin class, often leads to use of broader spectrum antibiotics with poor safety and efficacy profiles and represents a serious obstacle for antimicrobial stewardship. Risk factors for cephalosporin allergies are broad and include female sex, advanced age, and a history of another antibiotic or penicillin allergy; however, cephalosporins are readily tolerated even among individuals with true immediate-type allergies to penicillins. Cephalosporin cross-reactivity potential is related to the structural R1 side chain, and clinicians should be cognizant of R1 side chain similarities when prescribing alternate β-lactams in allergic individuals or when new cephalosporins are brought to market. Clinicians should consider the low likelihood of true cephalosporin allergy when clinically indicated. The purpose of this review is to provide an overview of the role of cephalosporins in clinical practice, and to highlight the incidence of, risk factors for, and cross-reactivity of cephalosporins with other antibiotics.
APA, Harvard, Vancouver, ISO, and other styles
5

Versporten, Ann, Robin Bruyndonckx, Niels Adriaenssens, Niel Hens, Dominique L. Monnet, Geert Molenberghs, Herman Goossens, et al. "Consumption of cephalosporins in the community, European Union/European Economic Area, 1997–2017." Journal of Antimicrobial Chemotherapy 76, Supplement_2 (July 1, 2021): ii22—ii29. http://dx.doi.org/10.1093/jac/dkab174.

Full text
Abstract:
Abstract Objectives Data on cephalosporin consumption in the community were collected from 30 EU/EEA countries over two decades. This article reviews temporal trends, seasonal variation, presence of change-points and changes in the composition of the main subgroups of cephalosporins. Methods For the period 1997–2017, data on consumption of cephalosporins (i.e. first-, second-, third- and fourth-generation cephalosporins; ATC subgroups J01DB, J01DC, J01DD and J01DE, respectively) in the community and aggregated at the level of the active substance, were collected using the WHO ATC/DDD methodology (ATC/DDD index 2019). Consumption was expressed in DDD per 1000 inhabitants per day and in packages per 1000 inhabitants per day. Cephalosporin consumption was analysed based on ATC-4 subgroup, and presented as trends, seasonal variation, presence of change-points and compositional changes. Results In 2017, cephalosporin consumption in the community expressed in DDD per 1000 inhabitants per day varied by a factor of 285 between countries with the highest (Greece) and the lowest (the Netherlands) consumption. Cephalosporin consumption did not change significantly between the first quarter of 1997 and the last quarter of 2017. Seasonal variation decreased significantly over time. Proportional consumption of second- and third-generation cephalosporins significantly increased over time compared with that of first-generation cephalosporins, and proportional consumption of fourth-generation cephalosporins significantly decreased compared with that of second- and third-generation cephalosporins. Conclusions Despite considerable variation between countries in the composition of cephalosporin consumption and trends over time, a significant shift towards consumption of more broad-spectrum cephalosporins in the community was observed across the EU/EEA during 1997–2017.
APA, Harvard, Vancouver, ISO, and other styles
6

Atanaskovic-Markovic, Marina, and Branimir Nestorovic. "Allergy to cephalosporin antibiotics in children." Srpski arhiv za celokupno lekarstvo 131, no. 3-4 (2003): 127–30. http://dx.doi.org/10.2298/sarh0304127a.

Full text
Abstract:
A particular problem is the safety of administering cephalosporins to penicillin-allergic children, because cephalosporin allergenic determinants have not been properly identified. Cephalosporin antibiotics are widely used to treat common infections and are often the first-line prophylaxis before many types of surgery. So the arm of this study is to determine the frequency of allergic reactions of anaphylactic type to cephalosporins and their cross-reactivity with penicillins. At University Children?s Hospital in Belgrade a group of 1,170 children with suspected anaphylactic allergic reaction to penicillins and/or cephalosporins were tested for the last eight years. Skin tests were performed with standard concentration of penicillins and cephalosporins. In children where skin tests were negative single-blind placebo-controlled challenges were performed. In case of positive skin tests further examinations were interrupted and the children were considered allergic to that drug. The frequency of anaphylactic allergic reactions to cephalosporins is 0.2 % to 17 %, and depends on cephalosporins generation. The cross-reactivity between cephalosporins and penicillins is 0.1 % to 14.5 %, and among cephalosporins is 0 % to 11.7 %.
APA, Harvard, Vancouver, ISO, and other styles
7

Djorić, Dušanka, and Christopher J. Kristich. "Oxidative Stress Enhances Cephalosporin Resistance of Enterococcus faecalis through Activation of a Two-Component Signaling System." Antimicrobial Agents and Chemotherapy 59, no. 1 (October 20, 2014): 159–69. http://dx.doi.org/10.1128/aac.03984-14.

Full text
Abstract:
ABSTRACTEnterococcus faecalisis a low-GC Gram-positive bacterium, a normal resident of the gastrointestinal (GI) tract, and an important hospital-acquired pathogen. An important risk factor for hospital-acquired enterococcal infections is prior therapy with broad-spectrum cephalosporins, antibiotics that impair cell wall biosynthesis by inhibiting peptidoglycan cross-linking. Enterococci are intrinsically resistant to cephalosporins; however, environmental factors that modulate cephalosporin resistance have not been described. While searching for the genetic determinants of cephalosporin resistance inE. faecalis, we unexpectedly discovered that oxidative stress, whether from external sources or derived from endogenous metabolism, drives enhanced intrinsic resistance to cephalosporins. A particular source of oxidative stress, H2O2, activates signaling through the CroR-CroS two-component signaling system, a known determinant of cephalosporin resistance inE. faecalis. We find that CroR-CroS is required for adaptation to H2O2stress and that H2O2potentiates the activities of cephalosporins againstE. faecaliswhen the CroR-CroS signaling system is nonfunctional. Rather than directly detecting H2O2, our data suggest that the CroR-CroS system responds to cell envelope damage caused by H2O2exposure in order to promote cell envelope repair and enhanced cephalosporin resistance.
APA, Harvard, Vancouver, ISO, and other styles
8

Hameed, Tahir K., and Joan L. Robinson. "Review of the Use of Cephalosporins in Children with Anaphylactic Reactions from Penicillins." Canadian Journal of Infectious Diseases 13, no. 4 (2002): 253–58. http://dx.doi.org/10.1155/2002/712594.

Full text
Abstract:
OBJECTIVE: It is a widely accepted practice that children with anaphylaxis from penicillins should avoid cephalosporins. The purpose of the present study was to determine whether there is evidence in the literature to support this practice.DATA SOURCES: MEDLINE, EMBASE, Toxline, Inter-national Pharmaceutical Abstracts and PubMed were used to search the literature published from 1966 to 2001. The Canadian Medical Protective Association, Health Canada and the Boston Collaborative Drug Surveillance Program were also contacted to determine whether there were any unpublished cases of cross-reactivity between penicillins and cephalosporins.DATA EXTRACTION: Cases describing the use of cepha-losporins in adults and children with positive penicillin skin tests or anaphylaxis from penicillin were evaluated. Case reports of anaphylaxis from cephalosporins in paediatric patients were identified.DATA SYNTHESIS: There have been five reported cases of serious reactions from cephalosporins in patients with a history of anaphylaxis from penicillins. All cases occurred in adults; three developed anaphylaxis from the older, first-generation cephalosporins, cephalothin and cephaloridine; one developed anaphylaxis from cefamandole; and one developed anaphylaxis from cefaclor. There have been 12 other published reports of anaphylaxis from cephalosporins in adults with a history of penicillin allergy or a positive penicillin skin test, but with no history of anaphylaxis from penicillin. In seven studies, in which a total of 158 patients with positive penicillin skin tests were administered cephalosporins, seven had apparent immunoglobulin E-mediated reactions when they were given a cephalosporin. When the class of cephalosporin was able to be determined, none of the reports of reactions from cephalosporins in patients with allergies to penicillin involved third-generation cephalosporins. There have been 13 case reports of anaphylaxis from cephalosporins in paediatric patients.CONCLUSIONS: There are no published case reports of anaphylaxis from cephalosporins in children with anaphylaxis from penicillin, and there are only a small number of such reports in adults. Anaphylaxis from cephalosporins appears to be incredibly rare in children. There is minimal evidence in the literature to support the avoidance of cephalosporins in children with anaphylaxis from penicillins.
APA, Harvard, Vancouver, ISO, and other styles
9

Kaye, Keith S., Sara Cosgrove, Anthony Harris, George M. Eliopoulos, and Yehuda Carmeli. "Risk Factors for Emergence of Resistance to Broad-Spectrum Cephalosporins among Enterobacterspp." Antimicrobial Agents and Chemotherapy 45, no. 9 (September 1, 2001): 2628–30. http://dx.doi.org/10.1128/aac.45.9.2628-2630.2001.

Full text
Abstract:
ABSTRACT Among 477 patients with susceptible Enterobacter spp., 49 subsequently harbored third-generation cephalosporin-resistantEnterobacter spp. Broad-spectrum cephalosporins were independent risk factors for resistance (relative risk [OR] = 2.3, P = 0.01); quinolone therapy was protective (OR = 0.4, P = 0.03). There were trends toward decreased risk for resistance among patients receiving broad-spectrum cephalosporins and either aminoglycosides or imipenem. Of the patients receiving broad-spectrum cephalosporins, 19% developed resistance.
APA, Harvard, Vancouver, ISO, and other styles
10

Darville, Toni, and Terry Yamauchi. "The Cephalosporin Antibiotics." Pediatrics In Review 15, no. 2 (February 1, 1994): 54–62. http://dx.doi.org/10.1542/pir.15.2.54.

Full text
Abstract:
Introduction The first cephalosporin released for clinical use was cephalothin in 1964. Since that time, more than 20 cephalosporin antibiotics have been introduced. These are the most commonly prescribed antibiotics in the United States and account for the largest share of hospital expenditures. To determine which agent to use for an infection in a particular patient involves weighing competing claims of improved antibacterial spectrum, side effects, pharmacokinetics, and cost. This review will address these issues, as well as the basic mechanisms of action of the cephalosporins and their mechanisms of bacterial resistance. In addition, instances in which cephalosporins serve as appropriate alternatives or in which they offer distinct advantages over previously available antimicrobial agents will be described. Chemistry and Mechanism of Action Cephalosporins resemble penicillins (Fig.1) in that they have a β-lactam structure, but the five-member thiazolidine ring characteristic of the penicillins is replaced by a six-member dihydrothiazine ring (Fig. 2). The dihydrothiazine ring of the cephalosporins provides the molecule with the ability to resist bacterial enzymes; the antibacterial activity emanates from the β-lactam ring shared by penicillins and cephalosporins. Modifications at position 7 of the cephalosporin nucleus generally affect the antibacterial spectrum, and substitutions at position 3 of the dihydrothiazine ring alter the pharmacokinetics and metabolic parameters of the drug.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Cephalosporins"

1

Renault, Agnes J. "Formulary status of cephalosporins." Scholarly Commons, 1987. https://scholarlycommons.pacific.edu/uop_etds/498.

Full text
Abstract:
The primary purpose of this study is to analyze the formulary status of cephalosporins among a representative sample of hospitals in the United States. In addition, the research design attempts to determine the ranking of cephalsoporins in terms of acceptance to the hospitals' formulary and actual stocking of the cephaosoporin products. The study will attempt to ascertain the reasons for these rankings and the influence of DRG implementation, teaching status and hospital bed size on number of cephalosporins on formulary and in stock. This may yield insight into the strategies that hospitals are currently using to contain a significant proportion of their budget for pharmaceutical products
APA, Harvard, Vancouver, ISO, and other styles
2

LlinaÌ€s, Martí Antonio J. "Chemical reactivity of penicillins and cephalosporins." Thesis, University of Huddersfield, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273731.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Kythreoti, Georgia. "Green Routes to the Synthesis of Cephalosporins." Thesis, University of Manchester, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492767.

Full text
Abstract:
This thesis is concerned with studies on the enzyme carbamoyl transferase (CT) of the C cephalosporin intermediate (7-adipoyl-3-carbamoyloxymethyl cephalosporin) is an important step towards the demonstration of a novel and efficient bioprocess to make this intermediate.
APA, Harvard, Vancouver, ISO, and other styles
4

Lloyd, Christopher T. "New routes to some substituted penicillins and cephalosporins." Thesis, University of Edinburgh, 1992. http://hdl.handle.net/1842/15227.

Full text
Abstract:
Literature methods for the synthesis of benzyl 6-oxo-penicillanate have been studied, it was apparent that some of these reports contained conflicting information with regards to reaction conditions and yields. The same methodology was also used to synthesise the cephalosporin analogue t.butyl7-oxocephalosporanate. The reactions of these compounds with various trimethylsilyl amides and with the Wittig reagent 5'triphenylphosphoranylidenecyclohexanespiro-2'-(1',3'dioxolan)-4'-one have been investigated. The potential for attaching penicillin and cephalosporin nuclei to polymer supports, and thereby utilising the well developed methodology of solid phase peptide synthesis in the field of the discovery of novel β-lactam compounds, has been investigated. Difficulties were encountered when attempting to remove the β-lactams from the resin, however both penicillin and cephalosporin compounds were recovered, in low yield, having had the 6β-(7β-) amino protecting group changed whilst attached to the resin.
APA, Harvard, Vancouver, ISO, and other styles
5

Hill, Ryan Lee. "Studies on the enzymatic conversion of pencillins and cephalosporins." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318789.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Cheung, Kai Yan Keith. "Directed evolution towards the production of penicillins and cephalosporins." Thesis, University of Manchester, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.542790.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Buckwell, S. C. "The kinetics of the #beta#-lactamase catalysed hydrolysis of cephalosporins." Thesis, University of Huddersfield, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376437.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Challis, Gregory Leonard. "Studies on the biosynthesis of antimicrobial natural products." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390494.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Wood, Mark Elliott. "Studies in enzyme reaction mechanisms." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.256394.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Arezi, Bahram. "Mutational analysis of ACV synthetase in fungi." Thesis, University of Sheffield, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265916.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Cephalosporins"

1

Le, Huong. Drug utilization review on ceftizoxime. [Ottawa: Ottawa General Hospital], 1990.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

Cardinal, Louise. Evaluation of antianaerobic cephalosporins: focus on cefoxitin. Ottawa: Ottawa Civic Hospital, 1991.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

Ellison, Sara Fisher. Characteristics of demand for pharmaceutical products: An examination of four cephalosporins. Cambridge, Mass: Dept. of Economics, Massachusetts Institute of Technology, 1996.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

Radzio, Renate. Heterologe Genexpression in dem Cephalosporin C produzierenden Hyphenpilz Acremonium chrysogenum. Berlin: J. Cramer, 1997.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
5

Nosek, Jörg. Regulation spezifischer Gene in der Cephalosporin C Biosynthese von Acremonium chrysogenum. Berlin: J. Cramer, 1997.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

Glukoseregulation der Cephalosporin C-biosynthese im Hyphenpilz Acremonium chrysogenum. Berlin: J. Cramer, 1999.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
7

Faraci, W. Stephen. Inhibition of [beta]-lactamases by cephalosporins: Importance of the 3'-leaving group. Ann Arbor, Mich: U.M.I., 1988.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

Der Transkriptionsfaktor CPCR1, ein Regulator der Cephalosporin C-Biosynthesegene in Acremonoim chrysogenum. Berlin: J. Cramer, 1999.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
9

Kadurugamuwa, Jagath L. Influence of sub-inhibitory concentrations of cephalosporins on surface properties of klebsiella pneumoniae important in infection. Birmingham: University of Aston. Department of Pharmaceutical Sciences, 1985.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
10

Parker, James N., and Philip M. Parker. Omnicef: A medical dictionary, bibliography and annotated research guide to Internet references. San Diego, CA: ICON Health Publications, 2004.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Book chapters on the topic "Cephalosporins"

1

Finberg, Robert W., and Roy Guharoy. "Cephalosporins." In Clinical Use of Anti-infective Agents, 31–36. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4614-1068-3_5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Corallo, Carmela, and Syed Tabish R. Zaidi. "Cephalosporins." In Drug Dosing in Obesity, 27–38. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-44034-7_3.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Bloemendal, Sandra, and Ulrich Kück. "Cephalosporins." In Fungal Biology, 43–64. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1191-2_3.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

De Rosa, Margherita, and Anna Marabotti. "Cephalosporins." In Encyclopedia of Molecular Pharmacology, 1–11. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-21573-6_5371-1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Romano, Antonino, Rocco Luigi Valluzzi, and Francesco Gaeta. "Cephalosporins." In Cutaneous Drug Hypersensitivity, 177–86. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-82743-4_19.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Finberg, Robert W., and Roy Guharoy. "Cephalosporins." In Clinical Use of Anti-infective Agents, 39–46. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-67459-5_5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

De Rosa, Margherita, and Anna Marabotti. "Cephalosporins." In Encyclopedia of Molecular Pharmacology, 429–39. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57401-7_5371.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Nahata, Milap C. "Cephalosporins." In Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology, 117–22. Boca Raton: CRC Press, 2023. http://dx.doi.org/10.1201/9781003418153-21.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Bryskier, A., and M. Lebel. "Oral Cephalosporins." In Antimicrobial Agents, 222–68. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555815929.ch7.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Dalhoff, A. "First-Generation Cephalosporins." In Antibiotics and Chemotherapy, 28–38. Basel: KARGER, 1997. http://dx.doi.org/10.1159/000059295.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Cephalosporins"

1

Shearer, M., K. Andrassy, H. Bechtold, P. McCarthy, J. Koderisch, and H. Koderisch. "CEPHALOSPORIN-INDUCED HYPOPROTHROMBINAEMIA: RELATION TO CEPHALOSPORIN SIDE CHAIN, VITAMIN K METABOLISM AND VITAMIN K STATUS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643076.

Full text
Abstract:
An increased incidence of bleeding episodes due to hypopro-thrombinaemia has been associated with several cephalosporins especially those which contain an N-methyl-thio-tetrazole (NMTT) side chain. To study the etiology of cephalosporin-induced hypo-prothrombinaemia in the clinical situation we have investigated the ability of different cephalosporins to alter the metabolism of vitamin K and the relationship between hypoprothrombinaemia and vitamin K status as assessed from plasma levels of vitamin K. Cephalosporins containing an NMTT side chain (latamoxef, cefmenoxime, cefoperazone, cefotetan, cefamandole) or related structure (cefozolin) all caused the transient plasma appearance of vitamink1 2,3-epoxide in response to a 10 mg intravenous dose of vitamin ; those without NMTT (cefotaxime and cefoxitin) did not. The plasma accumulation of vitamin k1 2,3-epoxide was qualitatively similar to, but quantitatively less than, that produced by the oral anticoagulant phenprccoumon. In 36 patients eating normally, the median endogenous plasma vitamin k1 (370 pg/ml) was not significantly different from that in healthy, fasting subjects (372 pg/ml) and clotting tests remained consistently normal for all antibiotics tested. In 22 patients on total parenteral nutrition the median plasma vitamin k1. (223 pg/ml) was significantly lower than normal (p < 0.01) with 61patients having levels below the normal range (< 150 pg/ml) but normal clotting before starting antibiotic therapy. All 7 parenterally-fed patients treated with latamoxef developed hypoprothrombinaemia (as shown by prothrombin time, PIVKA-II and protein C measurements) within 4 days whereas 12 patients treated with cefotaxime or cefoxitin did not. Latamoxef-associated hypoprothrombinaemia was readily reversible by 1 mg of vitamin k1 given intravenously but hypoprothrombinaemia and sub-normal plasma vitamin k1 could recur within 2-3 days. The data suggest that NMTT-cephalosporins are inhibitors of hepatic vitamin K epoxide reductase and that a lowered vitamin K status predisposes to hypoprothrombinaemia.
APA, Harvard, Vancouver, ISO, and other styles
2

de Oliveira, Liliane Maciel, and Marlei Barboza. "Separation of cephalosporins using ionic and neutral polimeric resins." In 2012 IEEE 2nd Portuguese Meeting in Bioengineering (ENBENG). IEEE, 2012. http://dx.doi.org/10.1109/enbeng.2012.6331353.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Thomas, Jesse, A. Jeanine Abrams-Mclean, Sandra Seby, Matthew Schmerer, Cau Pham, Jaeyoung Hong, Sancta St Cyr, Kim Gernert, Brian Raphael, and Ellen Kersh. "O04.2 Phylogenomic analysis reveals persistence ofneisseria gonorrhoeaeclades with reduced susceptibility to cephalosporins." In Abstracts for the STI & HIV World Congress (Joint Meeting of the 23rd ISSTDR and 20th IUSTI), July 14–17, 2019, Vancouver, Canada. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/sextrans-2019-sti.123.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Su, Xiaohong, Wenjing Le, Xiangdi Lou, Xuechun Li, Xiangdong Gong, and Peter Rice. "P666 Increased resistance to extended-spectrum cephalosporins inneisseria gonorrhoeaeisolates in nanjing, china (2013–2018)." In Abstracts for the STI & HIV World Congress (Joint Meeting of the 23rd ISSTDR and 20th IUSTI), July 14–17, 2019, Vancouver, Canada. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/sextrans-2019-sti.733.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

BAQER, Batool Abd Al Ameer, and Maysoon Khaleefah ABBAS. "EFFECT OF CEPHALOSPORINS ON ( BIOFILM PRODUCTION AND PROTEASE ) ACTIVITIES BY SOME BACTERIA ISOLATED FROM OTITIS MEDIA." In III.International Scientific Congress of Pure,Appliedand Technological Sciences. Rimar Academy, 2021. http://dx.doi.org/10.47832/minarcongress3-1.

Full text
Abstract:
30 samples (swab) were collected from patients suffering from Otitis media. Swabs were implanted on the culture media blood agar and MacConkey agar to isolate the bacteria and to diagnose them using microscopic, culture and biochemical tests and confirmed by the Vitck-2 system. Of the total, 18 isolates were selected which belong to 8 (26.6%) Staphylococcus aureus, 5 (16.6%) Klebsiella pneumonia, and 4 (13.3%) Escherichia coli. All isolates were investigated for sensitivity to (18) antibiotics, six of them from the cephalosporins group The results showed that all isolates were 100% resistance to Cefotaxime, Ceftazidime, Cefixime, Ceftriaxone, Cefepime, Cefoxitin, Aztronam, Ampenicillin, while the isolates showed the lowest percentage of resistance to Imipenem (4.54) %, while all differences showed a clear difference in some of their resistance. Of the antagonists (Vancomycin, Erythromycin, Rifampin) with a percentage of (95.45, 27.27, 18.18)%, respectively. but for concentrations (4–16)µg/ml were ineffective for some of them. The (Minimal inhibitory concentrations ) MIC test indicated that it ranged between (4–32)µg/ml for Ceftriaxone and (16–32)µg/ml for Ceftazidime. All isolates were shown ability have (100%) activity to produce (Biofilm) was tested on the Congo red agar (CRA) medium, and ability to produce a protease enzyme by (72.22%) on Skim milk agar medium. The results showed a effect of inhibitory concentrations of Ceftriaxone on the activity of biofilm production and the protease enzyme, further the results of this study showed that the following concentrations (1024, 512, 256 and 128)µg/ml were lethal to isolates, while (32–64)µg/ml were inhibitory, Also, the molecular diagnosis shown results of Agarose - gel electrophoresis of both (normal case) S. aureus, E. coli and Kl. pneumonia and heal isolates observed the presence of chromosomal and plasmid DNA bands in the normal status but alone chromosomal DNA bands occur with the isolates deal in Ceftriaxone at levels of (32–128 )µg/ml. In the study of the effect of some Gram-negative bacteria by using IL-2 human. It can be used in the diagnosis of inflammation of the Otitis Media. Key words: Cephalosporins, Otitis media, Biofilm, protease, E. coli, Staphylococcus aureus, Klebsiella pneumonia.
APA, Harvard, Vancouver, ISO, and other styles
6

Qian, E. T., L. Wang, J. Stollings, J. D. Casey, T. W. Rice, and M. W. Semler. "The Association Between Piperacillin-Tazobactam versus Anti-Pseudomonal Cephalosporins and Major Adverse Kidney Events Among Critically Ill Adults." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2719.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Kovalenko, N. I., O. O. Vovk, and I. V. Novikova. "Sensitivity to cephalosporins of opportunistic bacteria, excreted in patients with infectious diseases of upper and lower respiratory tract." In SCIENTIFIC PROGRESS OF MEDICINE AND PHARMACY OF THE EU COUNTRIES. Baltija Publishing, 2021. http://dx.doi.org/10.30525/978-9934-26-075-9-15.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Radeva, Stephanie, Milena Bojkova, Denis Niyazi, Dobromira Savova, and Temenuga Stoeva. "Resistance Rates to Third-Generation Cephalosporins and Carbapenems in Serratia marcescens Isolates Obtained from Various Clinical Samples from Two Bulgarian Hospitals." In The 2nd International Electronic Conference on Antibiotics—Drugs for Superbugs: Antibiotic Discovery, Modes of Action and Mechanisms of Resistance. Basel Switzerland: MDPI, 2022. http://dx.doi.org/10.3390/eca2022-12693.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Klyueva, Violetta, Alexandr Sirotin, Elisaveta Rypalenko, Khristina Ozarko, and Khristina Degtyareva. "Antimicrobial Activity of Native and Nanoencapsulated Cephalosporin Antibiotics." In Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019). Paris, France: Atlantis Press, 2019. http://dx.doi.org/10.2991/isils-19.2019.35.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Liu, Ruobing, Xinran Li, and Fei Liu. "Design of cephalosporin detection system based on metamaterial infrared absorber." In International Conference on Optoelectronic Information and Functional Materials (OIFM 2023), edited by Yabo Fu and Kolla Bhanu Prakash. SPIE, 2023. http://dx.doi.org/10.1117/12.2686930.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Cephalosporins"

1

Markovska, Rumyana, Emma Keuleyan, Petya Stankova, Lyudmila Boyanova, Temenuga Stoeva, Mariana Murdjeva, Marya Sredkova, et al. Antimicrobial Susceptibility of Clinically Significant Isolates of Klebsiella pneumoniae and Escherichia coli Resistant to Cephalosporins Third Generation Collected from Patients in Bulgarian Hospitals. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, August 2018. http://dx.doi.org/10.7546/crabs.2018.08.16.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Stoeva, Temenuga, Rumiana Markovska, and Ivan Mitov. Molecular Epidemiology of Klebsiella pneumoniae Blood Isolates Resistant to 3rd Generation Cephalosporins and/or Carbapenems Collected from Patients in a Bulgarian University Hospital. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, October 2021. http://dx.doi.org/10.7546/crabs.2021.10.06.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Hutchinson, M. L., J. E. L. Corry, and R. H. Madden. A review of the impact of food processing on antimicrobial-resistant bacteria in secondary processed meats and meat products. Food Standards Agency, October 2020. http://dx.doi.org/10.46756/sci.fsa.bxn990.

Full text
Abstract:
For meat and meat products, secondary processes are those that relate to the downstream of the primary chilling of carcasses. Secondary processes include maturation chilling, deboning, portioning, mincing and other operations such as thermal processing (cooking) that create fresh meat, meat preparations and ready-to-eat meat products. This review systematically identified and summarised information relating to antimicrobial resistance (AMR) during the manufacture of secondary processed meatand meat products (SPMMP). Systematic searching of eight literature databases was undertaken and the resultantpapers were appraised for relevance to AMR and SPMMP. Consideration was made that the appraisal scores, undertaken by different reviewers, were consistent. Appraisal reduced the 11,000 initially identified documents to 74, which indicated that literature relating to AMR and SPMMP was not plentiful. A wide range of laboratory methods and breakpoint values (i.e. the concentration of antimicrobial used to assess sensitivity, tolerance or resistance) were used for the isolation of AMR bacteria.The identified papers provided evidence that AMR bacteria could be routinely isolated from SPMMP. There was no evidence that either confirmed or refuted that genetic materials capable of increasing AMR in non-AMR bacteria were present unprotected (i.e. outside of a cell or a capsid) in SPMMP. Statistical analyses were not straightforward because different authors used different laboratory methodologies.However, analyses using antibiotic organised into broadly-related groups indicated that Enterobacteriaceaeresistant to third generation cephalosporins might be an area of upcoming concern in SPMMP. The effective treatment of patients infected with Enterobacteriaceaeresistant to cephalosporins are a known clinical issue. No AMR associations with geography were observed and most of the publications identified tended to be from Europe and the far east.AMR Listeria monocytogenes and lactic acid bacteria could be tolerant to cleaning and disinfection in secondary processing environments. The basis of the tolerance could be genetic (e.g. efflux pumps) or environmental (e.g. biofilm growth). Persistent, plant resident, AMR L. monocytogenes were shown by one study to be the source of final product contamination. 4 AMR genes can be present in bacterial cultures used for the manufacture of fermented SPMMP. Furthermore, there was broad evidence that AMR loci could be transferred during meat fermentation, with refrigeration temperatures curtailing transfer rates. Given the potential for AMR transfer, it may be prudent to advise food business operators (FBOs) to use fermentation starter cultures that are AMR-free or not contained within easily mobilisable genetic elements. Thermal processing was seen to be the only secondary processing stage that served as a critical control point for numbers of AMR bacteria. There were significant linkages between some AMR genes in Salmonella. Quaternary ammonium compound (QAC) resistance genes were associated with copper, tetracycline and sulphonamide resistance by virtue of co-location on the same plasmid. No evidence was found that either supported or refuted that there was any association between AMR genes and genes that encoded an altered stress response or enhanced the survival of AMR bacteria exposed to harmful environmental conditions.
APA, Harvard, Vancouver, ISO, and other styles
4

Willis, C., F. Jorgensen, S. A. Cawthraw, H. Aird, S. Lai, M. Chattaway, I. Lock, E. Quill, and G. Raykova. A survey of Salmonella, Escherichia coli (E. coli) and antimicrobial resistance in frozen, part-cooked, breaded or battered poultry products on retail sale in the United Kingdom. Food Standards Agency, May 2022. http://dx.doi.org/10.46756/sci.fsa.xvu389.

Full text
Abstract:
Frozen, breaded, ready-to-cook chicken products have been implicated in outbreaks of salmonellosis. Some of these outbreaks can be large. For example, one outbreak of Salmonella Enteritidis involved 193 people in nine countries between 2018 and 2020, of which 122 cases were in the UK. These ready-to-cook products have a browned, cooked external appearance, which may be perceived as ready-to-eat, leading to mishandling or undercooking by consumers. Continuing concerns about these products led FSA to initiate a short-term (four month), cross-sectional surveillance study undertaken in 2021 to determine the prevalence of Salmonella spp., Escherichia coli and antimicrobial resistance (AMR) in frozen, breaded or battered chicken products on retail sale in the UK. This study sought to obtain data on AMR levels in Salmonella and E. coli in these products, in line with a number of other FSA instigated studies of the incidence and nature of AMR in the UK food chain, for example, the systematic review (2016). Between the beginning of April and the end of July 2021, 310 samples of frozen, breaded or battered chicken products containing either raw or partly cooked chicken, were collected using representative sampling of retailers in England, Wales, Scotland and Northern Ireland based on market share data. Samples included domestically produced and imported chicken products and were tested for E. coli (including extended-spectrum beta-lactamase (ESBL)-producing, colistin-resistant and carbapenem-resistant E. coli) and Salmonella spp. One isolate of each bacterial type from each contaminated sample was randomly selected for additional AMR testing to determine the minimum inhibitory concentration (MIC) for a range of antimicrobials. More detailed analysis based on Whole Genome Sequencing (WGS) data was used to further characterise Salmonella spp. isolates and allow the identification of potential links with human isolates. Salmonella spp. were detected in 5 (1.6%) of the 310 samples and identified as Salmonella Infantis (in three samples) and S. Java (in two samples). One of the S. Infantis isolates fell into the same genetic cluster as S. Infantis isolates from three recent human cases of infection; the second fell into another cluster containing two recent cases of infection. Countries of origin recorded on the packaging of the five Salmonella contaminated samples were Hungary (n=1), Ireland (n=2) and the UK (n=2). One S. Infantis isolate was multi-drug resistant (i.e. resistant to three different classes of antimicrobials), while the other Salmonella isolates were each resistant to at least one of the classes of antimicrobials tested. E. coli was detected in 113 samples (36.4%), with counts ranging from <3 to >1100 MPN (Most Probable Number)/g. Almost half of the E. coli isolates (44.5%) were susceptible to all antimicrobials tested. Multi-drug resistance was detected in 20.0% of E. coli isolates. E. coli isolates demonstrating the ESBL (but not AmpC) phenotype were detected in 15 of the 310 samples (4.8%) and the AmpC phenotype alone was detected in two of the 310 samples (0.6%) of chicken samples. Polymerase Chain Reaction (PCR) testing showed that five of the 15 (33.3%) ESBL-producing E. coli carried blaCTX-M genes (CTX-M-1, CTX-M-55 or CTX-M-15), which confer resistance to third generation cephalosporin antimicrobials. One E. coli isolate demonstrated resistance to colistin and was found to possess the mcr-1 gene. The five Salmonella-positive samples recovered from this study, and 20 similar Salmonella-positive samples from a previous UKHSA (2020/2021) study (which had been stored frozen), were subjected to the cooking procedures described on the sample product packaging for fan assisted ovens. No Salmonella were detected in any of these 25 samples after cooking. The current survey provides evidence of the presence of Salmonella in frozen, breaded and battered chicken products in the UK food chain, although at a considerably lower incidence than reported in an earlier (2020/2021) study carried out by PHE/UKHSA as part of an outbreak investigation where Salmonella prevalence was found to be 8.8%. The current survey also provides data on the prevalence of specified AMR bacteria found in the tested chicken products on retail sale in the UK. It will contribute to monitoring trends in AMR prevalence over time within the UK, support comparisons with data from other countries, and provide a baseline against which to monitor the impact of future interventions. While AMR activity was observed in some of the E. coli and Salmonella spp. examined in this study, the risk of acquiring AMR bacteria from consumption of these processed chicken products is low if the products are cooked thoroughly and handled hygienically.
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Cephalosporins' for particular source types:
Journal articles Dissertations / Theses Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography