Academic literature on the topic 'Centrifugal Microfluidics'

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Journal articles on the topic "Centrifugal Microfluidics"

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Schwarz, I., S. Zehnle, T. Hutzenlaub, R. Zengerle, and N. Paust. "System-level network simulation for robust centrifugal-microfluidic lab-on-a-chip systems." Lab on a Chip 16, no. 10 (2016): 1873–85. http://dx.doi.org/10.1039/c5lc01525a.

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Schwemmer, F., S. Zehnle, D. Mark, F. von Stetten, R. Zengerle, and N. Paust. "A microfluidic timer for timed valving and pumping in centrifugal microfluidics." Lab on a Chip 15, no. 6 (2015): 1545–53. http://dx.doi.org/10.1039/c4lc01269k.

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Vargas, Matheus J. T., Michel K. Nieuwoudt, Rakesh Arul, David E. Williams, and M. Cather Simpson. "Direct laser writing of hydrophobic and hydrophilic valves in the same material applied to centrifugal microfluidics." RSC Advances 13, no. 32 (2023): 22302–14. http://dx.doi.org/10.1039/d3ra01749d.

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The fabrication of hydrophobic and hydrophilic surfaces, achieved using femtosecond and nanosecond laser treatments, and their subsequent integration into centrifugal microfluidics, resulted in a noticeable improvement in operation of microfluidic valves.
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Xie, Zhongqiang, Yongchao Cai, Jiahao Wu, Zhaokun Xian, and Hui You. "Research on the Centrifugal Driving of a Water-in-Oil Droplet in a Microfluidic Chip with Spiral Microchannel." Applied Sciences 12, no. 9 (April 26, 2022): 4362. http://dx.doi.org/10.3390/app12094362.

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Combining the advantages of droplet-based microfluidics and centrifugal driving, a method for centrifugally driving W/O droplets with spiral microchannel is proposed in this paper. A physical model of droplet flow was established to study the flow characteristics of the W/O droplet in the spiral microchannel driven by centrifugal force, and kinematic analysis was performed based on the rigid body assumption. Then, the theoretical formula of droplet flow rate was obtained. The theoretical value was compared with the actual value measured in the experiments. The result shows that the trend of the theoretical value is consistent with the measured value, and the theoretical value is slightly larger than the experimentally measured value caused by deformation. Moreover, it is found that the mode of centrifugal driving with spiral microchannel has better flow stability than the traditional centrifugal driving structure. A larger regulation speed range can be achieved by adjusting the motor speed without using expensive equipment or precise instruments. This study can provide a basis and theoretical reference for the development of droplet-based centrifugal microfluidic chips.
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Xie, Zhongqiang, Yongchao Cai, Jiahao Wu, Zhaokun Xian, and Hui You. "Research on the Centrifugal Driving of a Water-in-Oil Droplet in a Microfluidic Chip with Spiral Microchannel." Applied Sciences 12, no. 9 (April 26, 2022): 4362. http://dx.doi.org/10.3390/app12094362.

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Combining the advantages of droplet-based microfluidics and centrifugal driving, a method for centrifugally driving W/O droplets with spiral microchannel is proposed in this paper. A physical model of droplet flow was established to study the flow characteristics of the W/O droplet in the spiral microchannel driven by centrifugal force, and kinematic analysis was performed based on the rigid body assumption. Then, the theoretical formula of droplet flow rate was obtained. The theoretical value was compared with the actual value measured in the experiments. The result shows that the trend of the theoretical value is consistent with the measured value, and the theoretical value is slightly larger than the experimentally measured value caused by deformation. Moreover, it is found that the mode of centrifugal driving with spiral microchannel has better flow stability than the traditional centrifugal driving structure. A larger regulation speed range can be achieved by adjusting the motor speed without using expensive equipment or precise instruments. This study can provide a basis and theoretical reference for the development of droplet-based centrifugal microfluidic chips.
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Shi, Yuxing, Peng Ye, Kuojun Yang, Jie Meng, Jiuchuan Guo, Zhixiang Pan, Qiaoge Bayin, and Wenhao Zhao. "Application of Microfluidics in Immunoassay: Recent Advancements." Journal of Healthcare Engineering 2021 (July 15, 2021): 1–24. http://dx.doi.org/10.1155/2021/2959843.

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In recent years, point-of-care testing has played an important role in immunoassay, biochemical analysis, and molecular diagnosis, especially in low-resource settings. Among various point-of-care-testing platforms, microfluidic chips have many outstanding advantages. Microfluidic chip applies the technology of miniaturizing conventional laboratory which enables the whole biochemical process including reagent loading, reaction, separation, and detection on the microchip. As a result, microfluidic platform has become a hotspot of research in the fields of food safety, health care, and environmental monitoring in the past few decades. Here, the state-of-the-art application of microfluidics in immunoassay in the past decade will be reviewed. According to different driving forces of fluid, microfluidic platform is divided into two parts: passive manipulation and active manipulation. In passive manipulation, we focus on the capillary-driven microfluidics, while in active manipulation, we introduce pressure microfluidics, centrifugal microfluidics, electric microfluidics, optofluidics, magnetic microfluidics, and digital microfluidics. Additionally, within the introduction of each platform, innovation of the methods used and their corresponding performance improvement will be discussed. Ultimately, the shortcomings of different platforms and approaches for improvement will be proposed.
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Burger, Robert, Daniel Kirby, Macdara Glynn, Charles Nwankire, Mary O'Sullivan, Jonathan Siegrist, David Kinahan, et al. "Centrifugal microfluidics for cell analysis." Current Opinion in Chemical Biology 16, no. 3-4 (August 2012): 409–14. http://dx.doi.org/10.1016/j.cbpa.2012.06.002.

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Gorkin, Robert, Jiwoon Park, Jonathan Siegrist, Mary Amasia, Beom Seok Lee, Jong-Myeon Park, Jintae Kim, Hanshin Kim, Marc Madou, and Yoon-Kyoung Cho. "Centrifugal microfluidics for biomedical applications." Lab on a Chip 10, no. 14 (2010): 1758. http://dx.doi.org/10.1039/b924109d.

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Pishbin, Esmail, Amin Kazemzadeh, Mohammadreza Chimerad, Sasan Asiaei, Mahdi Navidbakhsh, and Aman Russom. "Frequency dependent multiphase flows on centrifugal microfluidics." Lab on a Chip 20, no. 3 (2020): 514–24. http://dx.doi.org/10.1039/c9lc00924h.

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Noroozi, Zahra, Horacio Kido, Miodrag Micic, Hansheng Pan, Christian Bartolome, Marko Princevac, Jim Zoval, and Marc Madou. "Reciprocating flow-based centrifugal microfluidics mixer." Review of Scientific Instruments 80, no. 7 (July 2009): 075102. http://dx.doi.org/10.1063/1.3169508.

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Dissertations / Theses on the topic "Centrifugal Microfluidics"

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Häberle, Stefan. "Multiphase microfluidics on a centrifugal platform /." Aachen : Shaker, 2008. http://d-nb.info/988194627/04.

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Schwemmer, Frank [Verfasser], and Roland [Akademischer Betreuer] Zengerle. "Advanced centrifugal microfluidics: timing, aliquoting and volume reduction." Freiburg : Universität, 2016. http://d-nb.info/1122647603/34.

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Häberle, Stefan [Verfasser]. "Multiphase Microfluidics on a Centrifugal Platform / Stefan Häberle." Aachen : Shaker, 2008. http://d-nb.info/1162790784/34.

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Zhao, Yunpeng [Verfasser], and Roland [Akademischer Betreuer] Zengerle. "Handling of microparticles for assay automation in centrifugal microfluidics." Freiburg : Universität, 2019. http://d-nb.info/120271269X/34.

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Zhao, Yunpeng Verfasser], and Roland [Akademischer Betreuer] [Zengerle. "Handling of microparticles for assay automation in centrifugal microfluidics." Freiburg : Universität, 2019. http://d-nb.info/120271269X/34.

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Zehnle, Steffen [Verfasser], and Roland [Akademischer Betreuer] Zengerle. "Pneumatic operations in centrifugal microfluidics - an enabling technology for assay automation." Freiburg : Universität, 2019. http://d-nb.info/117696786X/34.

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Strohmeier, Oliver [Verfasser], and Roland [Akademischer Betreuer] Zengerle. "Centrifugal microfluidics for nucleic acid analysis at the point-of-care." Freiburg : Universität, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:25-freidok-108743.

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Strohmeier, Oliver Verfasser], and Roland [Akademischer Betreuer] [Zengerle. "Centrifugal microfluidics for nucleic acid analysis at the point-of-care." Freiburg : Universität, 2016. http://d-nb.info/1120020999/34.

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Hin, Sebastian [Verfasser], and Roland [Akademischer Betreuer] Zengerle. "Reduction of system complexity in centrifugal microfluidics by magnetophoresis at continuous rotation and thermo-pneumatic bubble mixing." Freiburg : Universität, 2020. http://d-nb.info/1222908573/34.

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Mark, Daniel [Verfasser], and Roland [Akademischer Betreuer] Zengerle. "Unit operations for the integration of laboratory processes in the field of nucleic acid analysis based on centrifugal microfluidics = Einheitsoperationen für die Integration von Laborprozessen im Bereich der Nukleinsaeureanalytik basierend auf zentrifugaler Mikrofluidik." Freiburg : Universität, 2013. http://d-nb.info/1123477361/34.

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Books on the topic "Centrifugal Microfluidics"

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Häberle, Stefan. Multiphase microfluidics on a centrifugal platform. Aachen: Shaker, 2008.

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Book chapters on the topic "Centrifugal Microfluidics"

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Ducrée, Jens. "Centrifugal Microfluidics." In Encyclopedia of Microfluidics and Nanofluidics, 379–93. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4614-5491-5_203.

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Ducrée, Jens. "Centrifugal Microfluidics." In Encyclopedia of Microfluidics and Nanofluidics, 1–18. Boston, MA: Springer US, 2014. http://dx.doi.org/10.1007/978-3-642-27758-0_203-2.

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Kellogg, Gregory J., Todd E. Arnold, Bruce L. Carvalho, David C. Duffy, and Norman F. Sheppard. "Centrifugal Microfluidics: Applications." In Micro Total Analysis Systems 2000, 239–42. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-017-2264-3_55.

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Nwankire, Charles E., David J. Kinahan, and Jens Ducrée. "Centrifugal Flow Control." In Encyclopedia of Microfluidics and Nanofluidics, 368–79. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4614-5491-5_1784.

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Nwankire, Charles E., David J. Kinahan, and Jens Ducrée. "Centrifugal Flow Control." In Encyclopedia of Microfluidics and Nanofluidics, 1–14. Boston, MA: Springer US, 2014. http://dx.doi.org/10.1007/978-3-642-27758-0_1784-1.

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Henderson, Brian, David J. Kinahan, and Jens Ducrée. "The Centrifugal Microfluidic: Lab-on-a-Disc Platform." In Microfluidics for Biologists, 115–44. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-40036-5_5.

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King, Damien, and Jens Ducrée. "Optical Detection on Centrifugal Microfluidic Lab-on-a-Disc Platforms." In Encyclopedia of Microfluidics and Nanofluidics, 2535–42. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4614-5491-5_1785.

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King, Damien, and Jens Ducrée. "Optical Detection on Centrifugal Microfluidic Lab-on-a-disc Platforms." In Encyclopedia of Microfluidics and Nanofluidics, 1–10. Boston, MA: Springer US, 2013. http://dx.doi.org/10.1007/978-3-642-27758-0_1785-1.

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Zeng, Jun, Deb Banerjee, Manish Deshpande, John R. Gilbert, David C. Duffy, and Gregory J. Kellogg. "Design Analyses of Capillary Burst Valves in Centrifugal Microfluidics." In Micro Total Analysis Systems 2000, 579–82. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-017-2264-3_136.

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Madou, Marc J., Yumin Lu, Siyi Lai, Jim Lee, and Sylvia Daunert. "A Centrifugal Microfluidic Platform — A Comparison." In Micro Total Analysis Systems 2000, 565–70. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-017-2264-3_133.

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Conference papers on the topic "Centrifugal Microfluidics"

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Niedbalski, Nick, Seok-Won Kang, and Debjyoti Banerjee. "Numerical Study of Microchamber Filling in Centrifugal Microfluidics." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-63897.

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Numerical investigation of the transient, coupled hydrodynamic and thermal behavior of a novel polymerase chain reaction (PCR) centrifugal microfluidic system is presented in this study. The driving mechanism for flow within these devices is modeled as a combination of the capillary forces and rotationally induced pressure gradient working in opposition to viscous forces, which are functions of rotation speed and fluid properties. The physical properties of the working fluid are in turn functions of temperature, some of which can have significant variations over the operating temperature ranges of a PCR thermal cycle. The complex balance of viscous, capillary, and rotationally induced inertial forces are crucial factors in optimizing the design of such devices. Hence, the effects of temperature variation on the filling performance cannot be neglected. A commercial CFD code is utilized to simulate the filling of a microchamber when subjected to thermal conditions typical of a PCR thermal cycle. The numerical model accounts for the temperature dependence of the working fluid’s viscosity and surface tension by simultaneously solving the Navier-Stokes and energy equations. The free surface morphology (position, shape) and total chamber fill fraction as a function of time is predicted by using the volume of fluids (VOF) method. Comparison of the predictions from the temperature dependent numerical model to that which assume said physical properties to be constant, demonstrates the strong effect of the fluid’s viscosity and surface tension on the filling rate for various rotation speeds.
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Zhang, Yong, Jiwen Xiang, Yunxia Wang, Zheng Qiao, and Wanjun Wang. "A 3D printed centrifugal microfluidic platform for solid-phase-extraction and fluorescent detection of spilled oil in water." In Microfluidics, BioMEMS, and Medical Microsystems XVII, edited by Bonnie L. Gray and Holger Becker. SPIE, 2019. http://dx.doi.org/10.1117/12.2515719.

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Haeberle, S., L. Naegele, R. Burger, R. Zengerle, and J. Ducree. "Alginate micro-bead fabrication on a centrifugal microfluidics platform." In 2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2007. http://dx.doi.org/10.1109/memsys.2007.4433113.

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Zhang, Yong, Jiwen Xiang, Yunxia Wang, Zheng Qiao, and Wanjun Wang. "A novel gravity valve and its application in a 3D printed centrifugal fluidic-system for solid phase extraction (SPE)." In Microfluidics, BioMEMS, and Medical Microsystems XVIII, edited by Bonnie L. Gray and Holger Becker. SPIE, 2020. http://dx.doi.org/10.1117/12.2550845.

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Chen, Z., S. Qian, J. Wang, and H. H. Bau. "Buoyancy Driven Microfluidics." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-62303.

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It is not surprising that the use of buoyancy as a driving force in microfluidic systems has attracted little or no attention. Buoyant forces are proportional to the volume and do not scale favorably as the device size is reduced. Nevertheless, in certain biotechnological applications, one can produce sufficiently large buoyancy forces to generate fluid motion at velocities on the order of mm/s even in conduits with equivalent diameters of a few hundreds of microns. One example is the thermal polymerase chain reaction (PCR) for DNA amplification. In this process, the reagents’ temperature varies from about 55°C to 94°C. Such large temperature variations can induce significant buoyant forces. Another class of systems that can be driven by buoyant forces is rotating laboratories on a chip (lab on a CD). In such laboratories, large centrifugal accelerations may induce significant buoyant forces even when the temperature variations are relatively small. These temperature variations can be used to propel and control fluid flow.
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Mark, D., S. Haeberle, T. Metz, S. Lutz, J. Ducree, R. Zengerle, and F. von Stetten. "Aliquoting structure for centrifugal microfluidics based on a new pneumatic valve." In 2008 IEEE 21st International Conference on Micro Electro Mechanical Systems. IEEE, 2008. http://dx.doi.org/10.1109/memsys.2008.4443730.

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Xing Chen, Lele Song, Babak Assadsangabi, Jie Fang, Mohamed Sultan Mohamed Ali, and Kenichi Takahata. "Wirelessly addressable heater array for centrifugal microfluidics and escherichia coli sterilization." In 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2013. http://dx.doi.org/10.1109/embc.2013.6610796.

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Minghao, Yang, Liu Kangkang, Yang Jiachen, and Wang Guanghui. "Point-of-Care Chemiluminescence Immunoassay Centrifugal Microfluidics for Gastrin-17 Detection." In 2020 IEEE 5th Optoelectronics Global Conference (OGC). IEEE, 2020. http://dx.doi.org/10.1109/ogc50007.2020.9260468.

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Kruger, J., P. Bezuidenhout, and T. H. Joubert. "Inkjet-printed conductive features for rapid integration of electronic circuits in centrifugal microfluidics." In 2017 IEEE AFRICON. IEEE, 2017. http://dx.doi.org/10.1109/afrcon.2017.8095561.

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Roy, Pratanu, N. K. Anand, and Debjyoti Banerjee. "A Numerical Study of Unsteady Laminar Flow and Heat Transfer Through an Array of Rotating Rectangular Microchannels." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-64745.

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Centrifugal microfluidics plays an important role for enabling many novel applications in life sciences. By controlling the rotating frequency, fluids can be handled and controlled without any actual pumps, actuators or active valves, resulting in cost effective and miniaturized techniques for fluid transport, valving, metering, switching, splitting and separation of fluids. In order to get a vivid picture of the underlying physics of centrifugal microfluidics, we have modeled and simulated fluid flow and heat transfer for water flowing through an array of rotating rectangular microchannels. A finite volume technique based on semi implicit pressure based equation (SIMPLE) algorithm has been developed to solve the Naiver-Stokes equations for unsteady laminar flow. The energy equation has been solved by applying repeated thermal boundary conditions at the wall in cross stream direction. The simulations show significant deviation of velocity and temperature profiles for rotating flow than those of non-rotating case. The results are presented for different flow Reynolds number and rotational Reynolds number.
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