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1

Satterlie, R. A. "Do jellyfish have central nervous systems?" Journal of Experimental Biology 214, no. 8 (March 23, 2011): 1215–23. http://dx.doi.org/10.1242/jeb.043687.

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Stockwell, Jocelyn, Nabiha Abdi, Xiaofan Lu, Oshin Maheshwari, and Changiz Taghibiglou. "Novel Central Nervous System Drug Delivery Systems." Chemical Biology & Drug Design 83, no. 5 (March 14, 2014): 507–20. http://dx.doi.org/10.1111/cbdd.12268.

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3

Carelli, Valerio, and David C. Chan. "Mitochondrial DNA: Impacting Central and Peripheral Nervous Systems." Neuron 84, no. 6 (December 2014): 1126–42. http://dx.doi.org/10.1016/j.neuron.2014.11.022.

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4

Russell, John H. "Interaction Between the Immune and Central Nervous Systems." Immunologic Research 32, no. 1-3 (2005): 225–30. http://dx.doi.org/10.1385/ir:32:1-3:225.

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5

Mizunami, Makoto, and Toshifumi Takahashi. "The diversity of central nervous systems of invertebrates." Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 145, no. 3-4 (November 2006): 410. http://dx.doi.org/10.1016/j.cbpb.2006.10.027.

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6

Newhouse, Paul A., and Megan Kelton. "Nicotinic systems in central nervous systems disease: degenerative disorders and beyond." Pharmaceutica Acta Helvetiae 74, no. 2-3 (March 2000): 91–101. http://dx.doi.org/10.1016/s0031-6865(99)00047-3.

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7

Bae, Mihyeon, Hee-Gyeong Yi, Jinah Jang, and Dong-Woo Cho. "Microphysiological Systems for Neurodegenerative Diseases in Central Nervous System." Micromachines 11, no. 9 (September 16, 2020): 855. http://dx.doi.org/10.3390/mi11090855.

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Neurodegenerative diseases are among the most severe problems in aging societies. Various conventional experimental models, including 2D and animal models, have been used to investigate the pathogenesis of (and therapeutic mechanisms for) neurodegenerative diseases. However, the physiological gap between humans and the current models remains a hurdle to determining the complexity of an irreversible dysfunction in a neurodegenerative disease. Therefore, preclinical research requires advanced experimental models, i.e., those more physiologically relevant to the native nervous system, to bridge the gap between preclinical stages and patients. The neural microphysiological system (neural MPS) has emerged as an approach to summarizing the anatomical, biochemical, and pathological physiology of the nervous system for investigation of neurodegenerative diseases. This review introduces the components (such as cells and materials) and fabrication methods for designing a neural MPS. Moreover, the review discusses future perspectives for improving the physiological relevance to native neural systems.
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8

Quiroga, Sigmer Y., E. Carolina Bonilla, D. Marcela Bolaños, Fernando Carbayo, Marian K. Litvaitis, and Federico D. Brown. "Evolution of flatworm central nervous systems: Insights from polyclads." Genetics and Molecular Biology 38, no. 3 (September 2015): 233–48. http://dx.doi.org/10.1590/s1415-475738320150013.

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9

Жуков, М. А. "Analysis of interconnection between central nervous and cardiovascular systems." Electronics and Communications 19, no. 1 (March 3, 2014): 26–36. http://dx.doi.org/10.20535/2312-1807.2014.19.1.142301.

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10

Kim, Hyun Jung, and Woong Sun. "Adult Neurogenesis in the Central and Peripheral Nervous Systems." International Neurourology Journal 16, no. 2 (2012): 57. http://dx.doi.org/10.5213/inj.2012.16.2.57.

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11

Gordon, Tessa. "Nerve regeneration in the peripheral and central nervous systems." Journal of Physiology 594, no. 13 (July 1, 2016): 3517–20. http://dx.doi.org/10.1113/jp270898.

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12

Keynes, Roger, and Geoffrey Cook. "Segmentation of the chick central and peripheral nervous systems." International Journal of Developmental Biology 62, no. 1-2-3 (2018): 177–82. http://dx.doi.org/10.1387/ijdb.170297rk.

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13

Weber, Markus, and Andrew A. Eisen. "Magnetic stimulation of the central and peripheral nervous systems." Muscle & Nerve 25, no. 2 (January 28, 2002): 160–75. http://dx.doi.org/10.1002/mus.10038.

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14

Qiu, Boning, Nils Bessler, Kianti Figler, Maj‐Britt Buchholz, Anne C. Rios, Jos Malda, Riccardo Levato, and Massimiliano Caiazzo. "Bioprinting Neural Systems to Model Central Nervous System Diseases." Advanced Functional Materials 30, no. 44 (April 22, 2020): 1910250. http://dx.doi.org/10.1002/adfm.201910250.

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15

Holland, Linda Z., João E. Carvalho, Hector Escriva, Vincent Laudet, Michael Schubert, Sebastian M. Shimeld, and Jr-Kai Yu. "Evolution of bilaterian central nervous systems: a single origin?" EvoDevo 4, no. 1 (2013): 27. http://dx.doi.org/10.1186/2041-9139-4-27.

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16

Knopfel, Thomas, David Madge, Ferdinando Nicoletti, Thomas Knöpfel, David Madge, and Ferdinando Nicoletti. "Overview Central & Peripheral Nervous Systems: Metabotropic glutamate receptors." Expert Opinion on Therapeutic Patents 6, no. 10 (October 1996): 1061–67. http://dx.doi.org/10.1517/13543776.6.10.1061.

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17

Shannahoff-Khalsa, David. "Lateralized rhythms of the central and autonomic nervous systems." International Journal of Psychophysiology 11, no. 3 (December 1991): 225–51. http://dx.doi.org/10.1016/0167-8760(91)90017-r.

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18

Márquez, M., J. R. Pedregosa, J. López, P. Marco-Salazar, D. Fondevila, and M. Pumarola. "Canine Leishmaniosis in the Central and Peripheral Nervous Systems." Journal of Comparative Pathology 148, no. 1 (January 2013): 81. http://dx.doi.org/10.1016/j.jcpa.2012.11.142.

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19

Callander, G. E., and R. A. D. Bathgate. "Relaxin family peptide systems and the central nervous system." Cellular and Molecular Life Sciences 67, no. 14 (March 7, 2010): 2327–41. http://dx.doi.org/10.1007/s00018-010-0304-z.

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20

Peters, Cole W., Casey A. Maguire, and Killian S. Hanlon. "Delivering AAV to the Central Nervous and Sensory Systems." Trends in Pharmacological Sciences 42, no. 6 (June 2021): 461–74. http://dx.doi.org/10.1016/j.tips.2021.03.004.

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21

Popovic, Dejan, and Thomas Sinkjær. "Central nervous system lesions leading to disability." Journal of Automatic Control 18, no. 2 (2008): 11–23. http://dx.doi.org/10.2298/jac0802011p.

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The introductory tutorial to this special issue was written for readers with engineering background with the aim to provide the basis for comprehending better the natural motor control and the terminology used in description of impairments and disability caused by to CNS injuries and diseases. The tutorial aims to emphasize the differences between natural and artificial control, complexity of sensory-motor systems in humans, the high level of articulation redundancy, and the fact that all of the said systems are modified after the central nervous system lesion. We hope that the tutorial will simplify the following of the subsequent papers in this special issue dedicated to the use of electrical stimulation with surface electrodes for assisting motor functions.
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22

Zhong, Yinghui, and Ravi V. Bellamkonda. "Biomaterials for the central nervous system." Journal of The Royal Society Interface 5, no. 26 (May 13, 2008): 957–75. http://dx.doi.org/10.1098/rsif.2008.0071.

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Biomaterials are widely used to help treat neurological disorders and/or improve functional recovery in the central nervous system (CNS). This article reviews the application of biomaterials in (i) shunting systems for hydrocephalus, (ii) cortical neural prosthetics, (iii) drug delivery in the CNS, (iv) hydrogel scaffolds for CNS repair, and (v) neural stem cell encapsulation for neurotrauma. The biological and material requirements for the biomaterials in these applications are discussed. The difficulties that the biomaterials might face in each application and the possible solutions are also reviewed in this article.
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23

Kenmochi, Mutsumi, and Jos J. Eggermont. "Salicylate and quinine affect the central nervous system." Hearing Research 113, no. 1-2 (November 1997): 110–16. http://dx.doi.org/10.1016/s0378-5955(97)00137-8.

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24

Ono, Ayumi, Yumi Nakayama, Maki Inoue, Tokuma Yanai, and Tomoaki Murakami. "AA Amyloid Deposition in the Central and Peripheral Nervous Systems in Flamingos." Veterinary Pathology 57, no. 5 (July 17, 2020): 700–705. http://dx.doi.org/10.1177/0300985820939976.

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AA amyloidosis is characterized by amyloid deposition in systemic organs, but amyloid deposition in the central nervous system (CNS) or peripheral nervous system (PNS) is rare. In this study, AA amyloidosis was observed in 31 of 48 flamingos that died at a Japanese zoo. Almost all cases developed AA amyloidosis secondary to inflammatory diseases such as enteritis. Affected flamingos had AA amyloid deposition around blood vessels in periventricular white matter of the brain and in peripheral nerves. In addition, cerebral Aβ amyloidosis was observed in one of the 31 cases with AA amyloidosis. In conclusion, flamingos in the zoo commonly developed systemic amyloidosis with frequent amyloid deposition in the CNS and PNS, which seems to be a unique distribution in this avian species. Comparative pathological analyses in flamingos may help elucidate the pathogenesis of amyloid neuropathy.
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25

Spence, Paul, Rodrigo Franco, Andrew Wood, and John A. Moyer. "Section Review Central & Peripheral Nervous Systems: Mechanisms of apoptosis as drug targets in the central nervous system." Expert Opinion on Therapeutic Patents 6, no. 4 (April 1996): 345–66. http://dx.doi.org/10.1517/13543776.6.4.345.

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26

Rabinowitz, L., and R. I. Aizman. "The Central Nervous System in Potassium Homeostasis." Frontiers in Neuroendocrinology 14, no. 1 (January 1993): 1–26. http://dx.doi.org/10.1006/frne.1993.1001.

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27

Chikley, Ben-Ami, and Kontoyiannis. "Mucormycosis of the Central Nervous System." Journal of Fungi 5, no. 3 (July 8, 2019): 59. http://dx.doi.org/10.3390/jof5030059.

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Mucormycosis involves the central nervous system by direct extension from infected paranasal sinuses or hematogenous dissemination from the lungs. Incidence rates of this rare disease seem to be rising, with a shift from the rhino-orbital-cerebral syndrome typical of patients with diabetes mellitus and ketoacidosis, to disseminated disease in patients with hematological malignancies. We present our current understanding of the pathobiology, clinical features, and diagnostic and treatment strategies of cerebral mucormycosis. Despite advances in imaging and the availability of novel drugs, cerebral mucormycosis continues to be associated with high rates of death and disability. Emerging molecular diagnostics, advances in experimental systems and the establishment of large patient registries are key components of ongoing efforts to provide a timely diagnosis and effective treatment to patients with cerebral mucormycosis.
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28

Kobayashi, Taisuke, Futoshi Watanabe, Kiyofumi Gyo, and Hitoshi Miki. "Superficial Siderosis of the Central Nervous System." Otology & Neurotology 25, no. 2 (March 2004): 193–94. http://dx.doi.org/10.1097/00129492-200403000-00020.

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29

Wagner, Franca, Melanie Buchwalder, Roland Wiest, Marco D. Caversaccio, and Dominique Vibert. "Superficial Siderosis of the Central Nervous System." Otology & Neurotology 40, no. 1 (January 2019): 31–37. http://dx.doi.org/10.1097/mao.0000000000002071.

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30

Sydlowski, Sarah A., Michael J. Cevette, and Jon Shallop. "Superficial Siderosis of the Central Nervous System." Otology & Neurotology 32, no. 6 (August 2011): 900–908. http://dx.doi.org/10.1097/mao.0b013e31822558a9.

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31

Nemeth, Hajnalka, Jozsef Toldi, and Laszlo Vecsei. "Role of Kynurenines in the Central and Peripherial Nervous Systems." Current Neurovascular Research 2, no. 3 (July 1, 2005): 249–60. http://dx.doi.org/10.2174/1567202054368326.

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32

AbdelRazek, Mahmoud A., Nagagopal Venna, and John H. Stone. "IgG4-related disease of the central and peripheral nervous systems." Lancet Neurology 17, no. 2 (February 2018): 183–92. http://dx.doi.org/10.1016/s1474-4422(17)30471-4.

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33

Bedbrook, Claire N., Benjamin E. Deverman, and Viviana Gradinaru. "Viral Strategies for Targeting the Central and Peripheral Nervous Systems." Annual Review of Neuroscience 41, no. 1 (July 8, 2018): 323–48. http://dx.doi.org/10.1146/annurev-neuro-080317-062048.

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Recombinant viruses allow for targeted transgene expression in specific cell populations throughout the nervous system. The adeno-associated virus (AAV) is among the most commonly used viruses for neuroscience research. Recombinant AAVs (rAAVs) are highly versatile and can package most cargo composed of desired genes within the capsid's ∼5-kb carrying capacity. Numerous regulatory elements and intersectional strategies have been validated in rAAVs to enable cell type–specific expression. rAAVs can be delivered to specific neuronal populations or globally throughout the animal. The AAV capsids have natural cell type or tissue tropism and trafficking that can be modified for increased specificity. Here, we describe recently engineered AAV capsids and associated cargo that have extended the utility of AAVs in targeting molecularly defined neurons throughout the nervous system, which will further facilitate neuronal circuit interrogation and discovery.
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34

SHINTANI, Norihito, Kiyokazu OGITA, Hitoshi HASHIMOTO, and Akemichi BABA. "Recent Studies on the Trimethyltin Actions in Central Nervous Systems." YAKUGAKU ZASSHI 127, no. 3 (March 1, 2007): 451–61. http://dx.doi.org/10.1248/yakushi.127.451.

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35

Prokopowicz, Piotr, Dariusz Mikołajewski, Krzysztof Tyburek, and Piotr Kotlarz. "Fuzzy-based Description of Computational Complexity of Central Nervous Systems." Journal of Telecommunications and Information Technology 3 (September 30, 2020): 57–66. http://dx.doi.org/10.26636/jtit.2020.145620.

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Computational intelligence algorithms are currently capable of dealing with simple cognitive processes, but still remain inefficient compared with the human brain’s ability to learn from few exemplars or to analyze problems that have not been defined in an explicit manner. Generalization and decision-making processes typically require an uncertainty model that is applied to the decision options while relying on the probability approach. Thus, models of such cognitive functions usually interact with reinforcement-based learning to simplify complex problems. Decision-makers are needed to choose from the decision options that are available, in order to ensure that the decision-makers’ choices are rational. They maximize the subjective overall utility expected, given by the outcomes in different states and weighted with subjective beliefs about the occurrence of those states. Beliefs are captured by probabilities and new information is incorporated using the Bayes’ law. Fuzzy-based models described in this paper propose a different – they may serve as a point of departure for a family of novel methods enabling more effective and neurobiologically reliable brain simulation that is based on fuzzy logic techniques and that turns out to be useful in both basic and applied sciences. The approach presented provides a valuable insight into understanding the aforementioned processes, doing that in a descriptive, fuzzy-based manner, without presenting a complex analysis
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36

Carney, Joan, and Patricia Porter. "School reentry for children with acquired central nervous systems injuries." Developmental Disabilities Research Reviews 15, no. 2 (2009): 152–58. http://dx.doi.org/10.1002/ddrr.57.

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37

Rucker, Janet C. "Disorders of Myelin in the Central and Peripheral Nervous Systems." Journal of Neuro-Ophthalmology 24, no. 4 (December 2004): 349–50. http://dx.doi.org/10.1097/00041327-200412000-00020.

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38

WRIGHT, MALCOLM. "Physiology for General Practitioners. 1. Central Nervous and Endocrine Systems." Family Practice 5, no. 1 (1988): 46–55. http://dx.doi.org/10.1093/fampra/5.1.46.

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39

Swain, Christopher J. "Patent Update Central & Peripheral Nervous Systems: Neurokinin receptor antagonists." Expert Opinion on Therapeutic Patents 6, no. 4 (April 1996): 367–78. http://dx.doi.org/10.1517/13543776.6.4.367.

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40

Silverstone, Ph, and Aj Greenshaw. "Section Review Central & Peripheral Nervous Systems: 5-HT3receptor antagonists." Expert Opinion on Therapeutic Patents 6, no. 5 (May 1996): 471–81. http://dx.doi.org/10.1517/13543776.6.5.471.

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41

Shi, Ming, Dan Liu, Zhengyan Yang, and Ning Guo. "Central and peripheral nervous systems: master controllers in cancer metastasis." Cancer and Metastasis Reviews 32, no. 3-4 (May 15, 2013): 603–21. http://dx.doi.org/10.1007/s10555-013-9440-x.

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42

Rohlff, Christian. "Proteomics in molecular medicine: Applications in central nervous systems disorders." Electrophoresis 21, no. 6 (April 1, 2000): 1227–34. http://dx.doi.org/10.1002/(sici)1522-2683(20000401)21:6<1227::aid-elps1227>3.0.co;2-l.

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43

Tallini, Yvonne N., Bo Shui, Kai Su Greene, Ke-Yu Deng, Robert Doran, Patricia J. Fisher, Warren Zipfel, and Michael I. Kotlikoff. "BAC transgenic mice express enhanced green fluorescent protein in central and peripheral cholinergic neurons." Physiological Genomics 27, no. 3 (December 2006): 391–97. http://dx.doi.org/10.1152/physiolgenomics.00092.2006.

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The peripheral nervous system has complex and intricate ramifications throughout many target organ systems. To date this system has not been effectively labeled by genetic markers, due largely to inadequate transcriptional specification by minimum promoter constructs. Here we describe transgenic mice in which enhanced green fluorescent protein (eGFP) is expressed under the control of endogenous choline acetyltransferase (ChAT) transcriptional regulatory elements, by knock-in of eGFP within a bacterial artificial chromosome (BAC) spanning the ChAT locus and expression of this construct as a transgene. eGFP is expressed in ChATBAC-eGFP mice in central and peripheral cholinergic neurons, including cell bodies and processes of the somatic motor, somatic sensory, and parasympathetic nervous system in gastrointestinal, respiratory, urogenital, cardiovascular, and other peripheral organ systems. Individual epithelial cells and a subset of lymphocytes within the gastrointestinal and airway mucosa are also labeled, indicating genetic evidence of acetylcholine biosynthesis. Central and peripheral neurons were observed as early as 10.5 days postcoitus in the developing mouse embryo. ChATBAC-eGFP mice allow excellent visualization of all cholinergic elements of the peripheral nervous system, including the submucosal enteric plexus, preganglionic autonomic nerves, and skeletal, cardiac, and smooth muscle neuromuscular junctions. These mice should be useful for in vivo studies of cholinergic neurotransmission and neuromuscular coupling. Moreover, this genetic strategy allows the selective expression and conditional inactivation of genes of interest in cholinergic nerves of the central nervous system and peripheral nervous system.
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44

Durieux, Marcel E. "Muscarinic Signaling in the Central Nervous System." Anesthesiology 84, no. 1 (January 1, 1996): 173–89. http://dx.doi.org/10.1097/00000542-199601000-00020.

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During the last decade, major advances have been made in our understanding of the physiology and pharmacology of CNS muscarinic signaling. It is time to emphasize that the well-known peripheral parasympathetic and cardiovascular actions represent only one component of muscarinic signaling. Interestingly, many new findings have the potential to influence the practice of anesthesiology. Inhibition of muscarinic signaling may explain some of the anesthetic state, and subtype-selective drugs may allow wider perioperative manipulation of CNS muscarinic systems. The next years will doubtlessly see progress in this area, and our specialty may well reap the benefits.
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45

Lin, Yiqi Christina, and Vassilios Papadopoulos. "Neurosteroidogenic enzymes: CYP11A1 in the central nervous system." Frontiers in Neuroendocrinology 62 (July 2021): 100925. http://dx.doi.org/10.1016/j.yfrne.2021.100925.

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46

Servidei, S., A. Cianfoni, R. Di Giacopo, M. Catteruccia, G. Della Marca, D. Sauchelli, C. Cuccagna, and G. Primiano. "W12.2 Mitochondrial encephalomyopathies: central nervous system involvement." Clinical Neurophysiology 122 (June 2011): S38. http://dx.doi.org/10.1016/s1388-2457(11)60125-9.

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47

Aloisi, Anna Maria, and Marco Bonifazi. "Sex hormones, central nervous system and pain." Hormones and Behavior 50, no. 1 (June 2006): 1–7. http://dx.doi.org/10.1016/j.yhbeh.2005.12.002.

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48

van Bijsterveld, O. P. "Central nervous system mechanisms in Sjogren's syndrome." British Journal of Ophthalmology 87, no. 2 (February 1, 2003): 128–30. http://dx.doi.org/10.1136/bjo.87.2.128.

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49

OTTAWAY, C. "Central nervous system influences on lymphocyte migration." Brain, Behavior, and Immunity 6, no. 2 (June 1992): 97–116. http://dx.doi.org/10.1016/0889-1591(92)90011-c.

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50

Ayers, Joseph, Nikolai Rulkov, Dan Knudsen, Yong-Bin Kim, Alexander Volkovskii, and Allen Selverston. "Controlling Underwater Robots with Electronic Nervous Systems." Applied Bionics and Biomechanics 7, no. 1 (2010): 57–67. http://dx.doi.org/10.1155/2010/578604.

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We are developing robot controllers based on biomimetic design principles. The goal is to realise the adaptive capabilities of the animal models in natural environments. We report feasibility studies of a hybrid architecture that instantiates a command and coordinating level with computed discrete-time map-based (DTM) neuronal networks and the central pattern generators with analogue VLSI (Very Large Scale Integration) electronic neuron (aVLSI) networks. DTM networks are realised using neurons based on a 1-D or 2-D Map with two additional parameters that define silent, spiking and bursting regimes. Electronic neurons (ENs) based on Hindmarsh–Rose (HR) dynamics can be instantiated in analogue VLSI and exhibit similar behaviour to those based on discrete components. We have constructed locomotor central pattern generators (CPGs) with aVLSI networks that can be modulated to select different behaviours on the basis of selective command input. The two technologies can be fused by interfacing the signals from the DTM circuits directly to the aVLSI CPGs. Using DTMs, we have been able to simulate complex sensory fusion for rheotaxic behaviour based on both hydrodynamic and optical flow senses. We will illustrate aspects of controllers for ambulatory biomimetic robots. These studies indicate that it is feasible to fabricate an electronic nervous system controller integrating both aVLSI CPGs and layered DTM exteroceptive reflexes.
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