Academic literature on the topic 'Cellules – Vieillissement – Modèles animaux'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Cellules – Vieillissement – Modèles animaux.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Cellules – Vieillissement – Modèles animaux"
Guasch, Géraldine. "Les modèles animaux d’étude des cellules souches cancéreuses." Bulletin du Cancer 104, no. 12 (December 2017): 1064–67. http://dx.doi.org/10.1016/j.bulcan.2017.10.010.
Full textDembele, Mahamadou, Marion Delafosse, Nadhir Yousfi, Hanna Debiec, Kieu Ngo, Emmanuelle Plaisier, Pierre Ronco, and Guillaume Perry. "Modélisation de la barrière de filtration glomérulaire." médecine/sciences 37, no. 3 (March 2021): 242–48. http://dx.doi.org/10.1051/medsci/2021010.
Full textMonfort, Tual, Salvatore Azzollini, Nathaniel Norberg, Olivier Thouvenin, and Kate Grieve. "Imagerie 3D en direct : la tomographie par cohérence optique dynamique." Photoniques, no. 127 (2024): 32–36. http://dx.doi.org/10.1051/photon/202412737.
Full textGoureau, Olivier, and Gaël Orieux. "Nouvelle approche thérapeutique pour les rétinites pigmentaires." médecine/sciences 36, no. 6-7 (June 2020): 600–606. http://dx.doi.org/10.1051/medsci/2020097.
Full textGalas, Simon, Marie-Thérèse Château, Pascal Pomiès, Jing Wang, Julien Menardo, Jean-Luc Puel, Jean-Philippe Hugnot, Jean-Michel Verdier, and Gina Devau. "Aperçu de la diversité des modèles animaux dédiés à l’étude du vieillissement." médecine/sciences 28, no. 3 (March 2012): 297–304. http://dx.doi.org/10.1051/medsci/2012283018.
Full textVölkel, Pamela, Babara Dupret, Xuefen Le Bourhis, and Pierre-Olivier Angrand. "Le modèle poisson zèbre dans la lutte contre le cancer." médecine/sciences 34, no. 4 (April 2018): 345–53. http://dx.doi.org/10.1051/medsci/20183404016.
Full textHOUDEBINE, L. M. "La transgenèse animale et ses applications." INRAE Productions Animales 11, no. 1 (February 2, 1998): 81–94. http://dx.doi.org/10.20870/productions-animales.1998.11.1.3919.
Full textTachikart, Yassin, Olivier Malaise, Michaël Constantinides, Christian Jorgensen, and Jean-Marc Brondello. "Cibler les cellules sénescentes." médecine/sciences 34, no. 6-7 (June 2018): 547–53. http://dx.doi.org/10.1051/medsci/20183406014.
Full textToohey, Ann M., Jennifer A. Hewson, Cindy L. Adams, and Melanie J. Rock. "Pets, Social Participation, and Aging-in-Place: Findings from the Canadian Longitudinal Study on Aging." Canadian Journal on Aging / La Revue canadienne du vieillissement 37, no. 2 (April 10, 2018): 200–217. http://dx.doi.org/10.1017/s0714980818000107.
Full textBegon, Emmanuelle, and Valérie Bernard. "La prolactine et son récepteur : Des modèles animaux à la physiopathologie hypophysaire." Biologie Aujourd’hui 216, no. 3-4 (2022): 105–10. http://dx.doi.org/10.1051/jbio/2022019.
Full textDissertations / Theses on the topic "Cellules – Vieillissement – Modèles animaux"
Klein, Annabelle. "Characterization of developmental senescence using a new reporter mouse model to identify genes common across senescence states." Electronic Thesis or Diss., Strasbourg, 2024. http://www.theses.fr/2024STRAJ032.
Full textCellular senescence is a cellular state characterized by stable cell cycle arrest, numerous intracellular changes and a secretory phenotype. This process can be detrimental in many contexts, but can also be beneficial, for example during embryonic development. To date, there are no specific markers of cellular senescence. In this thesis project, I validated a new mouse model of senescence p21-mCherry-CreERT2, in vitro and in vivo. I then used this mouse to define the transcriptome of embryonic limb developmental senescence. This developmental senescence signature was then used to perform a meta-analysis with 18 other senescence studies, and identified numerous candidate genes that could be novel markers or mediators of senescence
Descamps, Olivier. "Sress oxydant et vieillissement : aspects mitochondriaux et stratégies nutritionnelles anti-cancer et anti-vieillissement chez la souris OF1." Université Joseph Fourier (Grenoble), 2004. http://www.theses.fr/2004GRE18008.
Full textOur thesis aimed to establish new perspectives about the link between the antioxidant status, the aging process and the cancer process, considering essentially the role played by mitochondria. A major part of our studies was devoted to evaluate nutritional strategies to prevent aging and cancer. Our objectives were to study the effects of calorie restriction or alternate feeding, selenium supplementation, that all proved striking efficacy, in contrast with the lack of effect of DHEA sulfate supplementation. A number of correlation studies between aging, longevity and various parameters of oxidative stress were evaluated: link between memory and antioxidant enzymes in brain and hippocampus, link between longevity and urinary level of 8-oxo-dGuo, the later appearing as highly significant. We concluded the thesis by the analysis of the correlation between the antioxidative defense system and the insect longevity
Bouchard, Martel Joanie. "Caractérisation des cellules interstitielles des quatre différentes valves cardiaques chez le porc." Thesis, Université Laval, 2008. http://www.theses.ulaval.ca/2008/25315/25315.pdf.
Full textGagnon, Nicolas. "Amélioration de la culture des cellules cornéennes endothéliales porcines." Master's thesis, Université Laval, 2007. http://hdl.handle.net/20.500.11794/19494.
Full textAshton-Chess, Joanna. "Modèles de xéno et d'allo - transplantations chez le babouin." Nantes, 2004. http://www.theses.fr/2004NANT03VS.
Full textThe aim of this PhD was to explore the most innovative strategies in the field of transplantation: xenotransplantation (Xt) and tolerance induction in allotransplantation (At), in the non human primate, a relevant preclinical model. The objective of the Xt part was to explore the various immunological mechanisms involved in the acute humoral xenograft rejection of porcine organs transgenic for human complement regulatory molecules (hCRM) by baboons. In our studies acute humoral xenograft rejection appeared to be similar to hyperacute rejection, albeit delayed in time and less aggressive, involving intragraft IgM deposition and complement activation through to the terminal membrane attack complex, even in the case of hCRM-transgenic organs. Rejection was also associated with an innate type response to the xenograft manifest as an cellular infiltrate creating a proinflammatory and cytotoxic environment, which, in some cases, was susceptible to immunosuppression. Surprisingly, survival was not prolonged by a single pretransplant immunoadsorption or by specific B cell-targeted immunosuppression with Mitoxanotrone, a novel agent in xenotransplantation. These issues will now need to be investigated in the case of the recently developed pigs negative for the Gal antigen, the initiator of this so far insurmountable humoral response. The objective of the At part was to explore different ways of inducing transplantation tolerance in the baboon based on strategies already established in vitro and in rodents, namely costimulation blockade and dendritic cells (DC). We firstly tested costimulation blockade alone and in combination with the potentially tolerance facilitating immunosuppressor, Rapamycin, and found this to be immunosuppressive only. This approach will now have to be supplemented with other immunological manoeuvres in order for tolerance to be achieved. We also extensively characterised baboon DC for the first time, derived in vitro from bone marrow and peripheral blood precursors. Further in vitro studies are now necessary to check the tolerance inducing capacity of these DC before they can be used as part of a protocol in vivo in the baboon, either alone, or in combination with costimulation blockade or immunosuppression
Plé, Coline. "Rôle des cellules Natural Killer dans l'asthme allergique." Phd thesis, Université du Droit et de la Santé - Lille II, 2010. http://tel.archives-ouvertes.fr/tel-00473006.
Full textMorisot, Sebastien. "Détermination of the frequency of leukemia stem cells in childhood precursor B cell acute lymphoblastic leukemias." Paris 11, 2009. http://www.theses.fr/2009PA11T022.
Full textMorosan, Serban-Zaharia. "Développement de modèles animaux pour l'étude des agents infectieux hépatotropes viraux." Angers, 2004. http://www.theses.fr/2004ANGE0509.
Full textHuman hepatocytes are essential for medical research, however are in very limited supply. Il has been recently reported that immunodeficient mice can be engrafted with human hepatocytes that remain susceptible to some extent to HBV and HCV. We combined these finding with previous indication that depletion of non-adaptative defences was critical to the survival of heterologous grafts. In Alb-upA/SCID mouse, the depletion of macrophages and NK cells dramatically improved the survival of human hepatocytes. The differentiation status of transplanted human hepatocytes was further confirmed by their receptivity to Plasmodium falciparum liver stages development for which no permissive cell line exist. In the present study, we have shown that primary human and rat hepatocytes can be efficiently transduced with a FLAP lentiviral vector without the need for plating and culture. Moreover, transplanted into Alb-uPA/SCID mouse liver, lentivirally transduced primary human hepatocytes extensively repopulated their liver and maintained a differentiated and functional phenotype as assessed by stable detection of human albumin an antitrypsin in the serum of the serum of the animals for months. This work therefore opens new perspectives for the development of human clinical trials based on liver-directed ex vivo gene therapy. Hélène Strick and al. Show that bipotential mouse embryonic liver (BMEL) cell lines are bipotential and differentiate into both hepatocyte and bile ducts. In this study we show that BMEL stem cell lines participate in liver regeneration in Alb-uPA/SCID transgenic mice. In the liver, the BMEL cells proliferate and differentiate into hepatocytes and bile ducts. This is the first report that immortalized stem cell lines not only are competent to participate in the repair of a damaged tissue, but that they can differentiate into two major epithelial cell types of a complex organ, hepatocytes and bile ducts. Once obsorbed, a drug under goes a collection of complex mechanisms of transformation, resulting in its elimination. Among the enzymatic system involved in the detoxification, the cytochromes P450 are, in most cases, responsible of the metabolism of drugs in the liver. In this study, we show that the livers of the Alb-uPA/SCID mice (transplanted with human hepatocytes) expressed a lot of Cytochromes P450 involved in the metabolism of drugs
Mekary-Sawaya, Souha. "Synthèse de quelques analogues du naftidrofuryl : premiers résultats sur les taux de mortalité de la gerbille après une ischémie cérébrale." Paris 11, 1990. http://www.theses.fr/1990PA114815.
Full textCuffley, Kristine. "Développement par génie tissulaire d'un modèle d'étude in vitro des voies de signalisation des cellules souches du follicule pileux." Thesis, Université Laval, 2005. http://www.theses.ulaval.ca/2005/23211/23211.pdf.
Full textBooks on the topic "Cellules – Vieillissement – Modèles animaux"
Jörg, Traber, Gispen Willem Hendrik, and International Tropon-Bayer Symposium on Aging of the Brain (2nd : 1984 : Cologne, Germany), eds. Senile dementia of Alzheimer type: Early diagnosis, neuropathology, and animal models. Berlin: Springer-Verlag, 1985.
Find full textFilaretova, L. P. (Li︠u︡dmila Pavlovna) and Takeuchi K. (Koji), eds. Cell/tissue injury and cytoprotection/organoprotection in the gastrointestinal tract: Mechanisms, prevention, and treatment. Basel: Karger, 2012.
Find full textKioussi, Chrissa. Stem Cells and Tissue Repair: Methods and Protocols. Springer New York, 2016.
Find full textKioussi, Chrissa. Stem Cells and Tissue Repair: Methods and Protocols. Springer, 2020.
Find full textKioussi, Chrissa. Stem Cells and Tissue Repair: Methods and Protocols. Springer, 2021.
Find full textConference papers on the topic "Cellules – Vieillissement – Modèles animaux"
MAGNOL, Laetitia, Magali SAGE, Karine VUILLIER, Anne DRUILHE, and Séverine NADAUD. "L’utilisation des animaux en sciences : pourquoi et comment ?" In Les journées de l'interdisciplinarité 2022. Limoges: Université de Limoges, 2022. http://dx.doi.org/10.25965/lji.213.
Full text