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Stern, Steven E., and Benjamin E. Grounds. "Cellular Telephones and Social Interactions." International Journal of Technoethics 2, no. 1 (January 2011): 43–49. http://dx.doi.org/10.4018/jte.2011010104.
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Changes in technology often affect patterns of social interaction. In the current study, the authors examined how cellular telephones have made it possible for members of romantically involved couples to keep track of each other. The authors surveyed 69 undergraduates on their use of cellular telephones as well as their relationships and their level of sexual jealously. Results find that nearly a quarter of romantically involved cellular telephone users report tracking their significant other, and evidence shows that tracking behavior correlates with jealousy. Furthermore, participants frequently reported using countermeasures such as turning off their cellular telephones in order to avoid being tracked by others. In conclusion, newer communication technologies afford users to act upon protectiveness and jealousy more readily than before these technologies were available to the general public.
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Galloway, Gantt P., Ryne Didier, Kathleen Garrison, and John Mendelson. "Feasibility of Ecological Momentary Assessment Using Cellular Telephones in Methamphetamine Dependent Subjects." Substance Abuse: Research and Treatment 1 (January 2008): SART.S428. http://dx.doi.org/10.4137/sart.s428.
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Background Predictors of relapse to methamphetamine use are poorly understood. State variables may play an important role in relapse, but they have been difficult to measure at frequent intervals in outpatients. Methods We conducted a feasibility study of the use of cellular telephones to collect state variable data from outpatients. Six subjects in treatment for methamphetamine dependence were called three times per weekday for approximately seven weeks. Seven questionnaires were administered that assessed craving, stress, affect and current type of location and social environment. Results 395/606 (65%) of calls attempted were completed. The mean time to complete each call was 4.9 (s.d. 1.8) minutes and the mean time to complete each item was 8.4 (s.d. 4.8) seconds. Subjects rated the acceptability of the procedures as good. All six cellular phones and battery chargers were returned undamaged. Conclusion Cellular telephones are a feasible method for collecting state data from methamphetamine dependent outpatients.
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Pouliot, Chantal. "Students' inventory of social actors concerned by the controversy surrounding cellular telephones: A case study." Science Education 92, no. 3 (2008): 543–59. http://dx.doi.org/10.1002/sce.20274.
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Maura Shifa Salsa Nabilla and Ima Amaliah. "Pengaruh Pengguna Telepon Seluler, Fasilitas Kesehatan dan Sanitasi terhadap Kemiskinan di Indonesia Tahun 2010-2022." Bandung Conference Series: Economics Studies 4, no. 1 (February 7, 2024): 294–300. http://dx.doi.org/10.29313/bcses.v4i1.11786.
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Abstract. Poverty is a complex and multidimensional problem because it is related to inadequacy in various aspects of life, including access to economic, social, cultural, political, access to health, education, and an adequate environment. The purpose of this study is to determine the influence and magnitude of the influence of mobile phone users, health and sanitation facilities on poverty in Indonesia. The data used in this study is secondary, namely time series from 2010 to 2022. The data processing technique in this study uses Ordinary Least Square (OLS). The analysis tool is E-views 12. The data in this study was obtained from the Central Bureau of Statistics, Ministry of Health, related scientific articles, books, and websites relevant to the discussion. From the results of the model estimation, there are two variables that partially affect poverty in Indonesia, namely mobile phone users and health facilities at a confidence level of 1%. This means that increasing cellular phone service facilities and adding health facilities can reduce poverty rates in Indonesia. Meanwhile, the sanitation variable has no partial effect on poverty in Indonesia, because it has a probability value greater than 0.05. The large variation of independent variables, namely cellular telephone services, health facilities and sanitation against poverty in Indonesia is 89.49% and the rest (10.51%) is due to variations in other variables that are not included in the estimation model.
Abstrak. Kemiskinan merupakan permasalahan yang memiliki banyak aspek dan pelik karena mencakup keterbatasan dalam semua aspek kehidupan, seperti ekonomi, sosial, budaya, politik, akses terhadap layanan kesehatan, pendidikan, dan lingkungan yang layak. Tujuan dari penelitian ini adalah untuk mengetahui dampak dan luasnya dampak penggunaan telepon seluler, layanan kesehatan, dan fasilitas sanitasi terhadap tingkat kemiskinan di Indonesia. Penelitian ini menggunakan data sekunder yaitu time series dengan rentang waktu tahun 2010 hingga tahun 2022. Penelitian ini menggunakan pendekatan pengolahan data Ordinary Least Square (OLS). Alat analisisnya yaitu E-views 12. Data-data dalam penelitian ini didapatkan dari Badan Pusat Statistik, Kementrian Kesehatan, artikel ilmiah terkait, buku, dan website yang relevan dengan pembahasan. Dari hasil estimasi model ada dua variable yang secara parsial berpengaruh terhadap kemiskinan di Indonesia yaitu pengguna telepon seluler dan fasilitas kesehatan pada tingkat kepercayaan 1%. Artinya peningkatan fasilitas layanan telepon seluler dan penambahan fasilitas kesehatan dapat menurunkan tingkat kemiskinan di Indonesia. Sementara itu variable sanitasi secara parsial tidak berpengaruh terhadap kemiskinan di Indonesia, karena memiliki nilai probabilitas lebih besar dari 0.05. Adapun besarnya variasi variable independent yaitu layanan telpon seluler, fasilitas kesehatan dan sanitasi terhadap kemiskinan di Indonesia adalah sebesar 89,49% dan sisanya (10,51%) karena variasi variable lain yang tidak dimasukkan dalam model estimasi.
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Turner, Mark, Steve Love, and Mark Howell. "Understanding emotions experienced when using a mobile phone in public: The social usability of mobile (cellular) telephones." Telematics and Informatics 25, no. 3 (August 2008): 201–15. http://dx.doi.org/10.1016/j.tele.2007.03.001.
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Haryati, Asti. "Online Counseling Sebagai Alternatif Strategi Konselor dalam Melaksanakan Pelayanan E-Counseling di Era Industri 4.0." Bulletin of Counseling and Psychotherapy 2, no. 2 (September 9, 2020): 27–38. http://dx.doi.org/10.51214/bocp.v2i2.33.
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The use of media in providing counseling services greatly affects the skills of counselors in conducting counseling through virtual internet media. The development of communication technology in the era of 4.0 makes counselors more familiar with, utilizing and applying counseling media virtually via the internet. The development of communication technology requires counselors to innovate, especially in providing e-counseling services as a forum for counselors to provide alternative solutions to problems faced by counselees. This research method is descriptive qualitative research, the source of this research data comes from document studies in the form of books and previous research which is used as a source of data that supports research. The results of this study indicate that online counseling is in the form of virtual counseling technology media, namely: websites, telephones or cellphones, email, video conferencing, chat, instant messaging, computers and other social media networks. The ethics that must be considered by online counselors are how to establish good relationships via the internet, confidentiality aspects in the implementation of counseling, legal aspects in telecommunications via the internet and licensing. Thus online counselors are required to work professionally by paying attention to ethics in the implementation of online counseling.
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Heiriyah, Ainun, and Sri Ayatani Hayati. "Upaya Meningkatkan Kepekaan Sosial Melalui Layanan Konseling Kelompok Dengan Teknik Modeling pada MTs Al-Ikhwan Banjarmasin." Bulletin of Counseling and Psychotherapy 2, no. 2 (September 9, 2020): 39–48. http://dx.doi.org/10.51214/bocp.v2i2.35.
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The use of media in providing counseling services greatly affects the skills of counselors in conducting counseling through virtual internet media. The development of communication technology in the era of 4.0 makes counselors more familiar with, utilizing and applying counseling media virtually via the internet. The development of communication technology requires counselors to innovate, especially in providing e-counseling services as a forum for counselors to provide alternative solutions to problems faced by counselees. This research method is descriptive qualitative research, the source of this research data comes from document studies in the form of books and previous research which is used as a source of data that supports research. The results of this study indicate that online counseling is in the form of virtual counseling technology media, namely: websites, telephones or cellphones, email, video conferencing, chat, instant messaging, computers and other social media networks. The ethics that must be considered by online counselors are how to establish good relationships via the internet, confidentiality aspects in the implementation of counseling, legal aspects in telecommunications via the internet and licensing. Thus online counselors are required to work professionally by paying attention to ethics in the implementation of online counseling.
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Sajna, Radosław. "Nowe media – perspektywy badawcze." Świat Idei i Polityki 10, no. 1 (2010): 133–46. http://dx.doi.org/10.15804/siip201007.
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The term “new media” should be considered in accordance to the temporal and spatial context, because something “new” could be “new” only now and here or would be “new” only someday and somewhere, and not forever and everywhere. Therefore it is necessary to take into consideration that hundreds years ago the press was “new”, in the 20th Century the radio and television became “new media”, and today the term “new media” means, above all, the Internet, mobile telephones and other digital media. Nevertheless, R.D. Wimmer and J.R. Dominick describe the term “new media” in broader context, taking into consideration also different implications of the ICT to the human and social life. There are many different aspects of the “new media” that need to be investigated, and many of them are subjects of many studies realized by scientists from different countries. They research the impact of the “new media” to the traditional mass media, the influence of the Internet on politics and the political marketing, but also other social, economical and communicational aspects of this complex phenomenon. It is important also that the “new media” are useful tools for the researchers on every stage of any scientific investigation. There is strong need to investigate the “new media” in different contexts to understand better the new modern reality.
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Muzaffar, W. "Mine blast injuries: ocular and social aspects." British Journal of Ophthalmology 84, no. 6 (June 1, 2000): 626–30. http://dx.doi.org/10.1136/bjo.84.6.626.
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Ma, Ji, Wei Ni, Jie Yin, Ren Ping Liu, Yuyu Yuan, and Binxing Fang. "Modeling Mobile Cellular Networks Based on Social Characteristics." International Journal of Computers Communications & Control 11, no. 4 (July 3, 2016): 480. http://dx.doi.org/10.15837/ijccc.2016.4.2054.
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Social characteristics have become an important aspect of cellular systems, particularly in next generation networks where cells are miniaturised and social effects can have considerable impacts on network operations. Traffic load demonstrates strong spatial and temporal fluctuations caused by users social activities. In this article, we introduce a new modelling method which integrates the social aspects of individual cells in modelling cellular networks. In the new method, entropy based social characteristics and time sequences of traffic fluctuations are defined as key measures, and jointly evaluated. Spectral clustering techniques can be extended and applied to categorise cells based on these key parameters. Based on the social characteristics respectively, we implement multi-dimensional clustering technologies, and categorize the base stations. Experimental studies are carried out to validate our proposed model, and the effectiveness of the model is confirmed through the consistency between measurements and model. In practice, our modelling method can be used for network planning and parameter dimensioning to facilitate cellular network design, deployments and operations.
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Lee, Chuan-Min. "Clique Transversal Variants on Graphs: A Parameterized-Complexity Perspective." Mathematics 11, no. 15 (July 28, 2023): 3325. http://dx.doi.org/10.3390/math11153325.
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The clique transversal problem and its variants have garnered significant attention in the last two decades due to their practical applications in communication networks, social-network theory and transceiver placement for cellular telephones. While previous research primarily focused on determining the polynomial-time solvability or NP-hardness/NP-completeness of specific graphs, this paper adopts a parameterized-complexity approach. It thoroughly explores four clique transversal variants: the d-fold transversal problem, the {d}-clique transversal problem, the signed clique transversal problem and the minus clique transversal problem. The paper presents various findings regarding the parameterized complexity of the clique transversal problem and its variants. It establishes the W[2]-completeness and para-NP-completeness of the d-fold transversal problem, the {d}-clique transversal problem, the signed clique transversal problem and the minus clique transversal problem within specific graph classes. Additionally, it introduces fixed-parameter tractable algorithms for planar graphs and graphs with bounded treewidth, offering efficient solutions for these specific instances of the problems. The research further explores the relationship between planar graphs and graphs with bounded treewidth to enhance the time complexity of the d-fold clique transversal problem and the {d}-clique transversal problem. By analyzing the parameterized complexity of the clique transversal problem and its variants, this research contributes to our understanding of the computational limitations and potentially efficient algorithms for solving these problems.
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Korner, Paul I., and Frans H. H. Leenen. "Hypertension: Blood pressure regulating systems: cellular, integrative, and therapeutic aspects." Canadian Journal of Physiology and Pharmacology 65, no. 8 (August 1, 1987): 1515. http://dx.doi.org/10.1139/y87-238.
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This is only the second time in the long history of the International Physiological Congresses that a symposium on hypertension has formed part of the official satellite programme. After the 1983 IUPS Congress in Sydney, John Chalmers organized a magnificent satellite meeting at the Flinders Medical Centre in South Australia and we felt that we wished to continue the "tradition." Hypertension research has provided a wonderful example in recent years of how exciting it can be to apply very basic discoveries to the solution of practical problems. This meeting breaks new ground in being the first scientific event sponsored jointly by the Canadian Hypertension Society and the Australian High Blood Pressure Council. The meeting was made possible by generous financial support from Pfizer Canada and Pfizer Australia with, as co-contributors, Bayer Germany and Sandoz Australia. We would also like to acknowledge the help of Mrs. A. Garat of Pfizer Canada Medical Services in the organization of the meeting and Dr. Andrew Rankin who was responsible for all local arrangements.The Hypertension Satellite was held at Whistler, B.C., July 19–21, 1986, following the 30th International Congress of the International Union of Physiological Sciences in Vancouver. It provided a good forum for interdisciplinary information exchange. It also proved to be a pleasant social occasion in the beautiful setting of the coastal range of the Canadian Rockies. There were 48 invited speakers from Canada, Australia, Europe, the U.S.A., Japan, and New Zealand. We were fortunate in having as our patrons two great names in hypertension research, Dr. Arthur Guyton and Dr. Sydney Friedman.Emphasis was on a large range of mechanisms that regulate blood pressure. There were sessions on cell biology, the kidney, autonomic nervous regulation, peptides (including, of course, atrial natriuretic peptide and arginine vasopressin), and pathogenesis. The proceedings provide an up-to-date account of the position of the current "state of the art" in a number of important areas.
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Glasner, Peter. "Cellular division: social and political complexity in Indian stem cell research." New Genetics and Society 28, no. 3 (September 2009): 283–96. http://dx.doi.org/10.1080/14636770903151976.
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Lee, Kyootai, and Haim Mano. "Beyond Simple Innovativeness: A Hierarchical Continuum and Thinking and Feeling Processing Modes." Social Behavior and Personality: an international journal 42, no. 4 (May 15, 2014): 597–613. http://dx.doi.org/10.2224/sbp.2014.42.4.597.
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We tested a model of consumer innovativeness composed of two critical features. The first constituted a hierarchy ranging from cardinal personality traits to manifest behavioral innovativeness, and the second encompassed the distinction between the functional and experiential aspects of innovativeness. Cellular phones and MP3 players were the two innovative products we used to conduct a test of our proposed model. The results revealed that the hierarchy was manifested throughout the trait-behavior continuum but, was at least partially fractured in the link between marketplace traits and domain-specific innovativeness. The results supported a distinction between functional and experiential facets of innovativeness.
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Shuv-Ami, Avichai. "The impact of the social protest on brand commitment." Journal of Enterprising Communities: People and Places in the Global Economy 10, no. 3 (August 8, 2016): 249–61. http://dx.doi.org/10.1108/jec-11-2013-0038.
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Purpose This paper aims to present changes in customer brand commitment and its components in relation to the cellular and financial markets using three sets of data that were collected before, during and after the social protests of the Summer of 2011 in Israel. Design/methodology/approach The four data sets for this study were collected from an internet panel and represent the Hebrew-speaking segment of Israel’s population. The current study examines two markets; cellular provider companies and financial service companies. The surveys were carried out at different points in time which extended from April 2011 to March 2012. The first two surveys were carried out in March 2011 and May 2011, before the outbreak of the protests the Summer of 2011. A third survey was conducted in August 2011 during the protest. The last and the fourth survey was conducted in March 2012 after the wave of protests had died down. Findings The current research shows that as a result of the social protest movement, consumers have changed. They perceive brands as not being as good (perceived performance) as they were before the protest; they are less satisfied with the brands they used previously; and they are less loyal and committed to them. Practical implications The findings of this study signify a major change in marketing and in basic aspects of consumer behavior. Brands have become less important than before the protest. Testing two markets, cellular and financial, this research suggests that the social protest movement reduced the attachment of consumers to brands they most often bought. Originality/value No study has tested the impact over time of the social protest on several consumer behavior variables, including brand loyalty, brand involvement, satisfaction, consumer perceptions of their brands’ performance and brand commitment.
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Aurelian, Sorina, Adela Ciobanu, Roxana Cărare, Simona-Isabelle Stoica, Aurelian Anghelescu, Vlad Ciobanu, Gelu Onose, et al. "Topical Cellular/Tissue and Molecular Aspects Regarding Nonpharmacological Interventions in Alzheimer’s Disease—A Systematic Review." International Journal of Molecular Sciences 24, no. 22 (November 20, 2023): 16533. http://dx.doi.org/10.3390/ijms242216533.
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One of the most complex and challenging developments at the beginning of the third millennium is the alarming increase in demographic aging, mainly—but not exclusively—affecting developed countries. This reality results in one of the harsh medical, social, and economic consequences: the continuously increasing number of people with dementia, including Alzheimer’s disease (AD), which accounts for up to 80% of all such types of pathology. Its large and progressive disabling potential, which eventually leads to death, therefore represents an important public health matter, especially because there is no known cure for this disease. Consequently, periodic reappraisals of different therapeutic possibilities are necessary. For this purpose, we conducted this systematic literature review investigating nonpharmacological interventions for AD, including their currently known cellular and molecular action bases. This endeavor was based on the PRISMA method, by which we selected 116 eligible articles published during the last year. Because of the unfortunate lack of effective treatments for AD, it is necessary to enhance efforts toward identifying and improving various therapeutic and rehabilitative approaches, as well as related prophylactic measures.
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Eggebrecht, Adam T., Jed T. Elison, Eric Feczko, Alexandre Todorov, Jason J. Wolff, Sridhar Kandala, Chloe M. Adams, et al. "Joint Attention and Brain Functional Connectivity in Infants and Toddlers." Cerebral Cortex 27, no. 3 (January 7, 2017): 1709–20. http://dx.doi.org/10.1093/cercor/bhw403.
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Abstract Initiating joint attention (IJA), the behavioral instigation of coordinated focus of 2 people on an object, emerges over the first 2 years of life and supports social-communicative functioning related to the healthy development of aspects of language, empathy, and theory of mind. Deficits in IJA provide strong early indicators for autism spectrum disorder, and therapies targeting joint attention have shown tremendous promise. However, the brain systems underlying IJA in early childhood are poorly understood, due in part to significant methodological challenges in imaging localized brain function that supports social behaviors during the first 2 years of life. Herein, we show that the functional organization of the brain is intimately related to the emergence of IJA using functional connectivity magnetic resonance imaging and dimensional behavioral assessments in a large semilongitudinal cohort of infants and toddlers. In particular, though functional connections spanning the brain are involved in IJA, the strongest brain-behavior associations cluster within connections between a small subset of functional brain networks; namely between the visual network and dorsal attention network and between the visual network and posterior cingulate aspects of the default mode network. These observations mark the earliest known description of how functional brain systems underlie a burgeoning fundamental social behavior, may help improve the design of targeted therapies for neurodevelopmental disorders, and, more generally, elucidate physiological mechanisms essential to healthy social behavior development.
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Baritz, Mihaela Ioana. "Analyze of Temperature Effects Induced by Cellular Phones in the Human Head and Eye." Applied Mechanics and Materials 330 (June 2013): 287–90. http://dx.doi.org/10.4028/www.scientific.net/amm.330.287.
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In this paper it is presented some theoretical and experimental aspects about effect of long period using of mobile phone by different human subjects. In first part of paper it is presented the electromagnetic radiations analyze taking into account their interaction with human body. To study these interactions we develop an experimental methodology using a set of mobile phones and instruments to measure the thermal effect manifested at the skin surface and head and also the effect on visual function. The results and conclusions are presented in the final part of paper also the social and technical implications are studied and presented.
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Yang, Fan, Xiangjun Bai, Xiaojing Dai, and Yong Li. "The biological processes during wound healing." Regenerative Medicine 16, no. 4 (April 2021): 373–90. http://dx.doi.org/10.2217/rme-2020-0066.
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Numerous individuals suffer from impaired wound healing, such as chronic ulcers, severe burns and immune disorders, resulting in both public health and economic burdens. Skin is the first line of defense and the largest organ of the human body, however, an incomplete understanding of underlying cellular and molecular mechanisms of dermal repair leads to a lack of effective therapy for healing impaired wounds. There are strong clinical and social needs for improved therapeutic approaches to enhance endogenous tissue repair and regenerative capacity. The purpose of this review is to illuminate the cellular and molecular aspects of the healing process and highlight potential therapeutic strategies to accelerate translational research and the development of clinical therapies in dermal wounds.
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Eymoi, Mohamed Ibrahim, and Patrick Mbataru. "The Role of Mobile Phone Technology in Resolving Communal Conflicts in Mandera County, Kenya." International Journal of Current Aspects 4, no. 2 (September 21, 2020): 69–80. http://dx.doi.org/10.35942/ijcab.v4i2.129.
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The unprecedented global adoption of information and communication technologies (ICTs) is rapidly changing the way people are communicating in solving problems. For several years now, the role of ICTs has become important in the way people construct their relationships in conflict resolution. Yet little is known on the dynamism of this interaction. It is not clear how mobile technology has contributed toward conflict resolution, and this study will contribute to the knowledge on the role of mobile telephones in conflict resolution. The purpose of this study was to explore how the mobile phone technology contributed in resolving communal conflicts in Mandera County, Kenya. This study was guided by three theories: conflict transformation theory, diffusion of innovations theory and social representation theory. The conflict Tansformation Theory is adopted as the main theory of analysis. The main idea of this theory is transforming negative conflict into constructive conflict, deals with structural, behavioural and attitudinal aspects of conflict. This study adopted a descriptive survey. The population for this study consisted of 301 employees in ICT and security department where stakeholders in technology and security sectors and the public. Primary and secondary data was analysed according to the objectives. Primary data was derived from questionnaires formulated to target employees in ICT and security department. The data analysis included qualitative and quantitative techniques. Qualitative data was summarized and categorized according to common themes and was presented using frequency distribution tables, graphs and charts. Content analysis was used mostly to arrive at inferences through a systematic and objective identification of the specific messages. The quantitative data collected was analyzed using descriptive statistics. The results confirmed that short message service, social media plateform, instant messaging applications, and video conferencing play a role in resolving communal conflicts in Mandera County. The study concludes that Short Message Service, Social Media Platforms and Instant Messaging Applications can be used conflict such as communal conflicts. Video Conferencing can be used to solve conflict such as relationship conflict, arises from differences in personality, style, matters of taste, and even conflict style as well as conflict in the workplace like task conflict. County government of Mandera must come up with ways of incorporating mobile phone technologies such as Short Message Service, Social Media Platforms, Instant Messaging and Video Conferencing on matters conflict resolution. The study recommends that the County Government of Mandera in collaboration with the National Government need to come up with agencies to regulate the use of social media as a medium to communicate in times of conflict since they are sometimes prone to misuse.
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Kogel, Friederike, and Silke Schicktanz. "P3-296: Genetic susceptibility for Alzheimer's disease: Social aspects and ethical issues." Alzheimer's & Dementia 8, no. 4S_Part_15 (July 2012): P563. http://dx.doi.org/10.1016/j.jalz.2012.05.1519.
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José Illnait-Ferrer, Julio César Fernández-Travieso, Yenney Reyes-Nuñez, and Alicia de la Caridad Duquesne-Chávez. "Ageing process and policosanol effects." World Journal of Advanced Research and Reviews 12, no. 2 (November 30, 2021): 273–83. http://dx.doi.org/10.30574/wjarr.2021.12.2.0242.
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The fundamental concepts of the aging process are exposed: Its dimension as a health problem, aspects related to its repercussion from the social point of view, and Its influence on aspects that can affect the normal development of contemporary society. The roles of genetics, cellular and biochemical processes that concur in the development of aging is analyzed, making special reference to the role of Adenosine Mono Phosphate Kinase [AMPK]. activation in the regulation of the aging process and the participation of mechanisms for its activation. It is concluded that Policosanol is a medicament of natural origin that could be proposed as candidate to be used for a healthy aging, based on the results of various investigations in experimental models and data obtained from different clinical trials.
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Sowkhya, B., S. Amaduzzi, and D. Raawal. "VISUALIZATION AND ANALYSIS OF CELLULAR & TWITTER DATA USING QGIS." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-4/W8 (July 11, 2018): 199–209. http://dx.doi.org/10.5194/isprs-archives-xlii-4-w8-199-2018.
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<p><strong>Abstract.</strong> The study is to understand individual presence and movement in Friuli Venezia Giulia region. It is important for tourism planning, hazard management, business marketing, implementing government lifetime policies and benefit. The aim of this study is achieved by advanced web<span class="thinspace"></span>2.0 applications. We need real time and geo-located data to monitor the inflow of tourist and to come up with effective promoting and benefiting plans for tourism, the evacuation and mitigation strategies during hazards to protect social life and environment with less infrastructure damage, marketing plans for advertising or selling of products. Despite wide spread success in predicting specific aspects of human behavior by social media information, a little attention is given to twitter and cell phone data. Accessibility to detailed human movements with fine spatial and temporal granularity is challenging due to confidentiality and safety reasons. With rapid development of web<span class="thinspace"></span>2.0 applications people can post about events, share opinion and emotions online. Using twitter data, how short term travelers, such as tourists, can be recognized and how their travel pattern can be analyzed. Study of finding tourist dynamics such as arriving and outgoing of tourist, sum of trips, sum of days and night spent, number of unique visitors, country of residence, main destination, secondary destination, transits pass through, repeat visits are achieved using CDR (call detail records) and DDR (data detail records).</p>
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Peruzzo, Roberta, Roberto Costa, Magdalena Bachmann, Luigi Leanza, and Ildikò Szabò. "Mitochondrial Metabolism, Contact Sites and Cellular Calcium Signaling: Implications for Tumorigenesis." Cancers 12, no. 9 (September 10, 2020): 2574. http://dx.doi.org/10.3390/cancers12092574.
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Mitochondria are organelles that are mainly involved in the generation of ATP by cellular respiration. In addition, they modulate several intracellular functions, ranging from cell proliferation and differentiation to cell death. Importantly, mitochondria are social and can interact with other organelles, such as the Endoplasmic Reticulum, lysosomes and peroxisomes. This symbiotic relationship gives advantages to both partners in regulating some of their functions related to several aspects of cell survival, metabolism, sensitivity to cell death and metastasis, which can all finally contribute to tumorigenesis. Moreover, growing evidence indicates that modulation of the length and/or numbers of these contacts, as well as of the distance between the two engaged organelles, impacts both on their function as well as on cellular signaling. In this review, we discuss recent advances in the field of contacts and communication between mitochondria and other intracellular organelles, focusing on how the tuning of mitochondrial function might impact on both the interaction with other organelles as well as on intracellular signaling in cancer development and progression, with a special focus on calcium signaling.
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Muljadi, Michael, Yi-Chen Fu, and Chao-Min Cheng. "Understanding the Cell’s Response to Chemical Signals: Utilisation of Microfluidic Technology in Studies of Cellular and Dictyostelium discoideum Chemotaxis." Micromachines 13, no. 10 (October 14, 2022): 1737. http://dx.doi.org/10.3390/mi13101737.
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Cellular chemotaxis has been the subject of a variety of studies due to its relevance in physiological processes, disease pathogenesis, and systems biology, among others. The migration of cells towards a chemical source remains a closely studied topic, with the Boyden chamber being one of the earlier techniques that has successfully studied cell chemotaxis. Despite its success, diffusion chambers such as these presented a number of problems, such as the quantification of many aspects of cell behaviour, the reproducibility of procedures, and measurement accuracy. The advent of microfluidic technology prompted more advanced studies of cell chemotaxis, usually involving the social amoeba Dictyostelium discoideum (D. discoideum) as a model organism because of its tendency to aggregate towards chemotactic agents and its similarities to higher eukaryotes. Microfluidic technology has made it possible for studies to look at chemotactic properties that would have been difficult to observe using classic diffusion chambers. Its flexibility and its ability to generate consistent concentration gradients remain some of its defining aspects, which will surely lead to an even better understanding of cell migratory behaviour and therefore many of its related biological processes. This paper first dives into a brief introduction of D. discoideum as a social organism and classical chemotaxis studies. It then moves to discuss early microfluidic devices, before diving into more recent and advanced microfluidic devices and their use with D. discoideum. The paper then closes with brief opinions about research progress in the field and where it will possibly lead in the future.
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Meyer, Magdalena, Kerstin Kuffner, Julia Winter, Inga D. Neumann, Christian H. Wetzel, and Benjamin Jurek. "Myocyte Enhancer Factor 2A (MEF2A) Defines Oxytocin-Induced Morphological Effects and Regulates Mitochondrial Function in Neurons." International Journal of Molecular Sciences 21, no. 6 (March 23, 2020): 2200. http://dx.doi.org/10.3390/ijms21062200.
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The neuropeptide oxytocin (OT) is a well-described modulator of socio-emotional traits, such as anxiety, stress, social behavior, and pair bonding. However, when dysregulated, it is associated with adverse psychiatric traits, such as various aspects of autism spectrum disorder (ASD). In this study, we identify the transcription factor myocyte enhancer factor 2A (MEF2A) as the common link between OT and cellular changes symptomatic for ASD, encompassing neuronal morphology, connectivity, and mitochondrial function. We provide evidence for MEF2A as the decisive factor defining the cellular response to OT: while OT induces neurite retraction in MEF2A expressing neurons, OT causes neurite outgrowth in absence of MEF2A. A CRISPR-Cas-mediated knockout of MEF2A and retransfection of an active version or permanently inactive mutant, respectively, validated our findings. We also identified the phosphatase calcineurin as the main upstream regulator of OT-induced MEF2A signaling. Further, MEF2A signaling dampens mitochondrial functioning in neurons, as MEF2A knockout cells show increased maximal cellular respiration, spare respiratory capacity, and total cellular ATP. In summary, we reveal a central role for OT-induced MEF2A activity as major regulator of cellular morphology as well as neuronal connectivity and mitochondrial functioning, with broad implications for a potential treatment of disorders based on morphological alterations or mitochondrial dysfunction.
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Thiel, Marie-Jo. "Engineering cellular systems: modify, repair, but not at all costs. Which ethical benchmarks?" Medicina e Morale 72, no. 1 (April 11, 2023): 39–47. http://dx.doi.org/10.4081/mem.2023.1226.
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This contribution examines the engineering of molecular and cellular system from an ethical point of view. It is possible today to modify, repair, and treat (…) but it must not be at all costs. Fascination must not blind us to the ethical issues at stake. In order to take on these challenges, the author proposes five sets of intertwined principles suggesting systematic and systemic levels of reasoning. The first set concerns recognition of a free, dignified, autonomous but also vulnerable human being who is at the centre of the ethical approach. A second set aims at the usefulness and reliability of the implemented engineering. Linked to the first two sets, the third one points to the place of information and education, assuming the uncertainties inherent in all human knowledge and the rapid evolution of cellular and molecular engineering techniques and their repercussions on the whole of society. A fourth set refers to social and societal values: justice, equal access to care, non-discrimination, cost of treatment and solidarity... and in addition: cultural and religious perspectives which can sometimes be brakes, sometimes accelerators... The last principle brings these different ethical issues together by stressing the obligation to take a global view: integrating time and space, and the opened prospects and their implications at the anthropological, social and societal, political, environmental, economic, cultural and religious levels.
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Purwantoro, Tono. "Kredibilitas Komunikator pada Destinasi Wisata Melalui Media Sosial (Video Viral Negeri di Atas Awan Citorek, Banten)." EKSPRESI DAN PERSEPSI : JURNAL ILMU KOMUNIKASI 3, no. 2 (July 30, 2020): 157. http://dx.doi.org/10.33822/jep.v3i2.1863.
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Abstrak. Telepon seluler (gawai) menjadi kebutuhan primer bagi masyarakat. Khalayak membutuhkannya sebagai sarana informasi, bersosialisasi atau pengungkapan diri dalam berkomunikasi. Arus pesan komunikasi melalui aplikasi instant messaging WhatsApp meningkat dan menduduki posisi pertama. Informasi yang disebarkan melalui WhatsApp sering menjadi viral. Misalnya peristiwa fenomenal tayangan video mengenai wahana wisata baru bernama Negeri Di Atas Awan, Citorek, Banten pada September 2019. Komunikator dalam tayangan adalah Pemimpin Daerah yang tidak disebutkan namanya namun komunikasi visual dalam video dan narasi yang diunggah berhasil memikat hati penerima pesan dan memviralkannya. Dalam hitungan hari, viral tayangan video lanjutan berisikan antusias masyarakat yang berkunjung. Namun, pengunjung kecewa karena mendapati fakta yang berbeda. Penelitian ini ingin melihat bagaimana kredibilitas komunikator pada destinasi wisata yang viral melalui media sosial. Penelitian menggunakan metode studi dokumen dengan pendekatan kualitatif desktiptif. Temuan menunjukkan, kredibilitas komunikator pada media digital menjadi kekuatan sesuai pernyataan McCorskey ada tiga nilai yaitu keahlian, karakter, dan kedinamisan yang tersajikan melalui komunikasi audio visual. Namun demikian, perlu diperhaikan cermat sehingga tidak menjadi kecewa. Kerelaan publik memviralkan menyebabkan kepanikan, dimana realitas yang tersaji dalam komunikasi visual tidak sesuai harapan yang dilihatnya. Kekuatan penyebaran pesan komunikasi visual melalui media aplikasi sosial hadir seperti dalam the bullet theory, pesannya cepat memiliki daya tarik antusiasme publik. Kata kunci: pesan singkat, komunikasi viral, komunikasi visual, video, media sosial, aplikasi wahatsapp Abstract. Cellular or mobile telephones for Indonesian people become the primary needs now. The audience needs it as a means of information, socializing or self-disclosure in interpersonal and group communication. The mobile phone used is increased.especialy use of WhatsApp (WA) instant messaging application which occupies the first position in Indonesia. Information distributed by WA immediately went viral such as the phenomenal event called Negeri Di Atas Awan, Citorek, Banten. The communicator in this video is the local Governor, but the visual communication and its narrative succeeded in capturing the heart of people were willing to see it. But then the visitors are disappointed to find different facts. This study wants to see how the communicator's credibility in tourist destinations through social media. The research used the document study method with a qualitative descriptive approach. The result is the credibility of communicator on digital media becomes a strength according to McCorskey's statement there are three values, namely expertise, character, and dynamism which are presented through audio-visual communication.The power of spreading visual communication messages through social media applications is present as in the bullet theory, the message quickly has the appeal of public enthusiasm.Keywords: instant messaging, viral communication, visual communication, video, social media, whatsapp aplication.
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Stephens, Neil, and Marianne Ellis. "Cellular agriculture in the UK: a review." Wellcome Open Research 5 (January 24, 2020): 12. http://dx.doi.org/10.12688/wellcomeopenres.15685.1.
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This review details the core activity in cellular agriculture conducted in the UK at the end of 2019, based upon a literature review by, and community contacts of the authors. Cellular agriculture is an emergent field in which agricultural products—most typically animal-derived agricultural products—are produced through processes operating at the cellular level, as opposed to (typically farm-based) processes operating at the whole organism level. Figurehead example technologies include meat, leather and milk products manufactured from a cellular level. Cellular agriculture can be divided into two forms: ‘tissue-based cellular agriculture’ and ‘fermentation-based cellular agriculture’. Products under development in this category are typically valued for their environmental, ethical, and sometimes health and safety advantages over the animal-derived versions. There are university laboratories actively pursuing research on meat products through cellular agriculture at the universities of Bath, Newcastle, Aberystwyth, and Aston University in Birmingham. A cellular agriculture approach to producing leather is being pursued at the University of Manchester, and work seeking to produce a palm oil substitute is being conducted at the University of Bath. The UK cellular agriculture companies working in the meat space are Higher Steaks, Cellular Agriculture Ltd, CellulaRevolution, Multus Media and Biomimetic Solutions. UK private investors include CPT Capital, Agronomics Ltd, Atomico, Backed VCs, and Breakoff Capital. The UK also has a strong portfolio of social science research into diverse aspects of cellular agriculture, with at least ten separate projects being pursued over the previous decade. Three analyses of the environmental impact of potential cellular agriculture systems have been conducted in the UK. The first dedicated third-sector group in this sector in the UK is Cultivate (who produced this report) followed by Cellular Agriculture UK. International groups New Harvest and the Good Food Institute also have a UK presence.
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Stephens, Neil, and Marianne Ellis. "Cellular agriculture in the UK: a review." Wellcome Open Research 5 (October 12, 2020): 12. http://dx.doi.org/10.12688/wellcomeopenres.15685.2.
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This review details the core activity in cellular agriculture conducted in the UK at the end of 2019, based upon a literature review by, and community contacts of the authors. Cellular agriculture is an emergent field in which agricultural products—most typically animal-derived agricultural products—are produced through processes operating at the cellular level, as opposed to (typically farm-based) processes operating at the whole organism level. Figurehead example technologies include meat, leather and milk products manufactured from a cellular level. Cellular agriculture can be divided into two forms: ‘tissue-engineering based cellular agriculture’ and ‘fermentation-based cellular agriculture’. Products under development in this category are typically valued for their environmental, ethical, and sometimes health and safety advantages over the animal-derived versions. There are university laboratories actively pursuing research on meat products through cellular agriculture at the universities of Bath, Newcastle, Aberystwyth, and Aston University in Birmingham. A cellular agriculture approach to producing leather is being pursued at the University of Manchester, and work seeking to produce a palm oil substitute is being conducted at the University of Bath. The UK cellular agriculture companies working in the meat space are Higher Steaks, Cellular Agriculture Ltd, CellulaRevolution, Multus Media and Biomimetic Solutions. UK private investors include CPT Capital, Agronomics Ltd, Atomico, Backed VCs, and Breakoff Capital. The UK also has a strong portfolio of social science research into diverse aspects of cellular agriculture, with at least ten separate projects being pursued over the previous decade. Three analyses of the environmental impact of potential cellular agriculture systems have been conducted in the UK. The first dedicated third-sector group in this sector in the UK is Cultivate (who produced this report) followed by Cellular Agriculture UK. International groups New Harvest and the Good Food Institute also have a UK presence.
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Constantinescu, Mihai, Ertan Onur, Yunus Durmus, Shahrokh Nikou, Mark de Reuver, Harry Bouwman, Miodrag Djurica, and Philipp Maria Glatz. "Mobile tethering: overview, perspectives and challengess." info 16, no. 3 (May 6, 2014): 40–53. http://dx.doi.org/10.1108/info-05-2013-0033.
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Purpose – The purpose of this paper is to analyze mobile tethering from technological and social perspectives. Mobile tethering allows us to share cellular data connection with others over WiFi, Bluetooth or USB. Although the technology is ready and has promising outcomes, service providers and the users still keep their distance. Therefore, the incentives for the users and service providers should be identified. Design/methodology/approach – Technical challenges in terms of energy and bandwidth consumption are explored using an application specifically developed for mobile tethering. Usage issues are studied through conjoint analysis, in which we analyze the importance of technical aspects as well as social conditions for sharing data connection with others. Findings – The research shows that although energy, bandwidth and security are important technical challenges, users are mainly concerned about social aspects, such as with whom the connection will be shared, rather than monetary issues. Mobile tethering is a viable cooperative service, only when users are familiar with the person with whom the data connection is being shared. Research limitations/implications – In the technical evaluation of the mobile tethering application, only Android operating systems are being used. Other operating systems (e.g. iOS) may perform differently. Moreover, only a small fraction of smartphones and tablets has been tested. Practical implications – Service providers tend to block mobile tethering technology, as they do not have control and do not expect to gain revenues. However, service providers have the abilities to satisfy the security and privacy concerns of the users and can create secure femtocells for their customers. Social implications – Mobile tethering performance results indicate that more people can access the Internet while they are mobile even if they do not have cellular data subscription. More Internet-based services can be offered to people while they roam in other countries. Originality/value – For technology developers, both the key technical issues and the concerns of the consumers are highlighted. Future applications must contain reliable security and privacy protocols in their design. Moreover, the significance of the social networks is shown in the decision-making of the use of mobile tethering, especially with respect to the credit exchange.
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Valiev, T. T. "Innovative advances in pediatric oncology and hematology: data of 54th Congress of the International Society of Paediatric Oncology (SIOP)." Russian Journal of Pediatric Hematology and Oncology 9, no. 4 (February 5, 2023): 125–28. http://dx.doi.org/10.21682/2311-1267-2022-9-4-125-128.
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The success in pediatric oncology and hematology diseases treatment opened the way to cure more than 90 % of patients with leukemias and lemphomas. The ability to share an achievements in modern paediatric oncology and hematology, to find an actual directions of development, to permit the specialists from every corner of the world to communicate and discuss the most difficult aspects in diagnosis and treatment of paediatric malignancies – the basis of the International Society of Paediatric Oncology (SIOP) work. In the current issue it is presented the thesis of reports of 54th SIOP Congress, which took place in Spain (Barcelona) from September 28 to October 1, 2022. New target drugs (blinatumomab, inotuzumab ozogamicin, dinutuximab, venetoclax, daratumumab, asciminib), cellular (CAR-T) and immune approaches for malignancies treatment, new achievements in supportive care, psychological and social aspects of medical care organization for paediatric patients with malignancies – only a few topics, that were discussed of the event.
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Lincoln, Karen D., Donald A. Lloyd, and Ann W. Nguyen. "Social Relationships and Salivary Telomere Length Among Middle-Aged and Older African American and White Adults." Journals of Gerontology: Series B 74, no. 6 (May 9, 2017): 1053–61. http://dx.doi.org/10.1093/geronb/gbx049.
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Abstract Objectives A common mechanism underlying premature morbidity may be accelerated biological aging as reflected by salivary telomere length (STL). This study examined the extent to which social relationships, both positive and negative, can be protective or confer risk relative to biological aging. Method Data from the Health and Retirement Study and multiple regression were used to examine cross-sectional associations between STL, self-reported social support, and negative interaction (e.g., conflict, criticism) with family in a nationally representative sample of African American and non-Hispanic White middle-aged and older adults (N = 4,080). Results Social support from family was associated with shorter STL. Negative interaction with family had no main effect on STL but interactions characterized by high social support and more frequent negative interactions were associated with longer STL. Negative interaction with family was negatively associated with STL for African Americans and Whites but the magnitude of the effect was greater for African Americans. Discussion Study findings highlight the role of social relationships in physiological deterioration among middle-aged and older adults and identify a potential mechanism whereby race is linked to accelerated biological aging. Findings highlight the importance of considering positive and negative aspects of social relationships to understand the consequences of social connections for cellular aging in diverse populations.
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Sophianingrum, Mada, Muhammad R. Islami, and Raditya H. Murti. "Urban-Rural Transformation and Urban Growth Scenario Using Cellular Automata in Lebak District - Banten Province." IOP Conference Series: Earth and Environmental Science 1264, no. 1 (November 1, 2023): 012033. http://dx.doi.org/10.1088/1755-1315/1264/1/012033.
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Abstract The development of Lebak District has been significant during the previous ten years, with the impact of urbanization, changing the community’s physical, social, and economic shape. The construction of the Serang-Panimbang toll road, which facilitates access to the Metropolitan City of DKI Jakarta, has rapidly transformed Lebak District, which indicates an urban-rural transformation. This study aims to see how rural-urban transformation occurs in Lebak District and to create a scenario of urban development in Lebak District in 2030. Assessment of the level and pattern of transformation based on physical, social, and economic aspects using geographic information system (GIS) applications is conducted. This research uses cellular automata to create urban development scenarios in Lebak District in 2030. The results of this study indicate that the urban-rural transformation in Lebak District occurred due to the influence of urbanization and the construction of a toll road that connects Lebak District with the metropolitan city of Jakarta. Lebak District has four development areas. First is the urban agglomeration of Rangkasbitung, the hub of administration and economy. Second, coastal development areas are located in the southern region of Lebak District. The third strategic development area is the toll road integration area, with a development plan for an integrated industrial region. The fourth location has modest development and is located in terrain with limited accessibility. The results of urban development scenarios using cellular automata show that the development of the Serang-Panimbang toll road led to an increase in urban growth by 21% in 2030.
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Wen, Tanya, Daniel J. Mitchell, and John Duncan. "The Functional Convergence and Heterogeneity of Social, Episodic, and Self-Referential Thought in the Default Mode Network." Cerebral Cortex 30, no. 11 (June 23, 2020): 5915–29. http://dx.doi.org/10.1093/cercor/bhaa166.
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Abstract The default mode network (DMN) is engaged in a variety of cognitive settings, including social, semantic, temporal, spatial, and self-related tasks. Andrews-Hanna et al. (2010; Andrews-Hanna 2012) proposed that the DMN consists of three distinct functional–anatomical subsystems—a dorsal medial prefrontal cortex (dMPFC) subsystem that supports social cognition; a medial temporal lobe (MTL) subsystem that contributes to memory-based scene construction; and a set of midline core hubs that are especially involved in processing self-referential information. We examined activity in the DMN subsystems during six different tasks: 1) theory of mind, 2) moral dilemmas, 3) autobiographical memory, 4) spatial navigation, 5) self/other adjective judgment, and 6) a rest condition. At a broad level, we observed similar whole-brain activity maps for the six contrasts, and some response to every contrast in each of the three subsystems. In more detail, both univariate analysis and multivariate activity patterns showed partial functional separation, especially between dMPFC and MTL subsystems, though with less support for common activity across the midline core. Integrating social, spatial, self-related, and other aspects of a cognitive situation or episode, multiple components of the DMN may work closely together to provide the broad context for current mental activity.
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Fitri*, Rini, Astrid Damayanti, Nur Intan Simangunsong, and Munawir ,. "Land Use Prediction Using Markov – Cellular Automata in the Peusangan Watershed, Aceh." Aceh International Journal of Science and Technology 11, no. 3 (January 25, 2023): 197–209. http://dx.doi.org/10.13170/aijst.11.3.25804.
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The population growth rate is a factor that causes changes in land use that impact land ecology due to increased population activities related to social, economic, and cultural aspects. Land use change aims to develop facilities and infrastructure to meet the population's needs. This research seeks to interpret land-use changes in 1999, 2008, and 2019 and predict land use in the Peusangan watershed in 2030. The map overlay method analyzes land use change in 1999-2008, 2008-2019, and 2019-2030. In predicting land use, this study uses the Cellular Automata approach. The results of the analysis specifically show that the trend of land use change until 2030 is a decrease in the area of forest land use covering an area of 11,014 ha (4.27%), open land covering an area of 31 ha (0.01%), shrubs 6,083 ha (2.36%), and water bodies covering an area of 459 ha (0.18%). On the other hand, it is predicted that in 2030 the Peusangan watershed will see the most significant increase in land use for plantations of 14,225 ha (5.52%), followed by land use of 1,664 ha (0.65%), 817 ha (0.32%), settlements covering 710 ha (0.28%), 132 ha of rice fields (0.05%), and 28 ha of pond land use (0.01%). The results of this study are expected to be input for policymakers regarding land use planning in the Peusangan watershed in the future
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Zjablovskaja, Polina, and Maria Carolina Florian. "Acute Myeloid Leukemia: Aging and Epigenetics." Cancers 12, no. 1 (December 31, 2019): 103. http://dx.doi.org/10.3390/cancers12010103.
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Acute myeloid leukemia (AML) is an aggressive hematological disorder mainly affecting people of older age. AML initiation is primarily attributed to mutations in crucial cellular regulators such as epigenetic factors, transcription factors, and signaling genes. AML’s aggressiveness and responsiveness to treatment depends on the specific cell type where leukemia first arose. Aged hematopoietic cells are often genetically and/or epigenetically altered and, therefore, present with a completely different cellular context for AML development compared to young cells. In this review, we summarize key aspects of AML development, and we focus, in particular, on the contribution of cellular aging to leukemogenesis and on current treatment options for elderly AML patients. Hematological disorders and leukemia grow exponentially with age. So far, with conventional induction therapy, many elderly patients experience a very poor overall survival rate requiring substantial social and medical costs during the relatively few remaining months of life. The global population’s age is increasing rapidly without an acceptable equal growth in therapeutic management of AML in the elderly; this is in sharp contrast to the increase in successful therapies for leukemia in younger patients. Therefore, a focus on the understanding of the biology of aging in the hematopoietic system, the development of appropriate research models, and new therapeutic approaches are urged.
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Zhuo, Zirong, Zhiwei Cheng, Yangzhou Lai, and Ziyue Chen. "Analysis of Company Human Capital Network Based on the Cellular Automation." International Journal of Business and Management 11, no. 5 (April 18, 2016): 244. http://dx.doi.org/10.5539/ijbm.v11n5p244.
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In the age of knowledge economy, human resource is among the most important resources for enterprises, in that it forms the unique value of human resources which plays an indispensable role in the production and operating activities. Well managed human resources can effectively promote efficiency and thus create more social values. Therefore, it has aroused wide attention in academia. The thesis first establish the human capital value model and the human cost value model, based on which the thesis established the basic framework of enterprise human capital network. Then, simulation calculation from three aspects of human resource network were carried out with the cellular automation model. Firstly, we simulated the dynamic process of the change of personnel and got the evaluation model of the human cost in the future two years of a company, which can provide reference for company cost control. Secondly, the simulation mainly focused on checking whether under high staff churn rate, a company can still maintain certain number of employees. Thirdly, we simulated the healthy status of the human resource network under certain situations. Finally, We concluded that higher staff churn rate can lead to higher vacancy rate, which will lower the efficiency of companies .The thesis also explored with the model sensitivity analysis the benefit effect over human resource network by increasing recruits, indicating that increasing recruits can decrease the vacancy rate and improve the health status of the human capital network and based on the reality, we put forward the improvement direction of the model in indicator system aspect.
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Ustin, Pavel, Fail Gafarov, and Andrey Berdnikov. "Analysis of Interpersonal Relationships of Social Network Users Using Explainable Artificial Intelligence Methods." OBM Neurobiology 07, no. 03 (August 24, 2023): 1–14. http://dx.doi.org/10.21926/obm.neurobiol.2303180.
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The emergence of the social networking phenomenon and the sudden spread of the coronavirus pandemic (COVID-19) around the world have significantly affected the transformation of the system of interpersonal relations, partly shifting them towards virtual reality. Online social networks have greatly expanded the boundaries of human interpersonal interaction and initiated processes of integration of different cultures. As a result, research into the possibilities of predicting human behavior through the characteristics of virtual communication in social networks has become more relevant. The aim of the study is: to explore the possibilities of machine learning model interpretability methods for interpreting the success of social network users based on their profile data. This paper uses a specific method of explainable artificial intelligence, SHAP (SHapley Additive exPlanations), to analyze and interpret trained machine learning models. The research is based on Social Network Analysis (SNA), a modern line of research conducted to understand different aspects of the social network as a whole as well as its individual nodes (users). User accounts on social networks provide detailed information that characterizes a user's personality, interests, and hobbies and reflects their current status. Characteristics of a personal profile also make it possible to identify social graphs - mathematical models reflecting the characteristics of interpersonal relationships of social network users. An important tool for social network analysis is various machine learning algorithms that make different predictions based on sets of characteristics (social network data). However, most of today's powerful machine learning methods are "black boxes," and therefore the challenge of interpreting and explaining their results arises. The study trained RandomForestClassifier and XGBClassifier models and showed the nature and degree of influence of the personal profile metrics of VKontakte social network users and indicators of their interpersonal relationship characteristics (graph metrics).
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Gjika, Jonida, and Renata Kau. "The Infrastructure for Providing Electronic Communication Services and its Impact on Effective Competition." Mediterranean Journal of Social Sciences 15, no. 1 (January 5, 2024): 93. http://dx.doi.org/10.36941/mjss-2024-0007.
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The infrastructure for providing electronic communication services and its impact on competitiveness, including 5G technology, has been focused on several key dimensions. These include the allocation of frequency spectrum, investments by cellular network operators, and the role of sectoral policies in the development of 5G technology. Spectrum allocation is a critical step in the development of 5G infrastructure, considering the regulatory authorities' role in ensuring effective frequency utilization. Operator investments in building 5G networks are a crucial factor for technological advancement and market competitiveness. Furthermore, these aspects must be assessed within the context of competition and performance growth in electronic communication services. Particularly, 5G technology represents a significant factor in enhancing network speed and capacity, offering innovative and adaptable services for users and industry. Security and privacy aspects are also crucial, emphasizing the need for effective policies and regulations to safeguard user data and ensure a reliable electronic communication environment. In this regard, it is appreciated that the development of electronic communication infrastructure, particularly with the establishment of 5G networks, has a profound impact on competitiveness, heralding a new era of advanced and personalized communication services. Another aspect involves the analysis of the market structure with two cellular operators in Albania and industry expectations for investments in 5G technology, rendering it a distinctive situation as a market dominated by a duopoly, given the absence of MVNOs, and the role of the effect reflected by the use of OTT services. The duopoly market structure can present challenges and advantages for the sector, also considered as a factor that may influence the development of 5G technology. Investments in 5G infrastructure are regarded as a crucial step to expedite progress and enhance cellular services within the country. Competition between the two operators underscores the importance of appropriate regulation to encourage investments and ensure a healthy competitive environment.
Received: 17 September 2023 / Accepted: 29 December 2023 / Published: 5 January 2024
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Jafarzadeh, Javad, Hossein Amoozad Khalili, and Naghi Shoja. "A Multiobjective Optimization Model for a Dynamic and Sustainable Cellular Manufacturing System under Uncertainty." Computational Intelligence and Neuroscience 2022 (September 22, 2022): 1–17. http://dx.doi.org/10.1155/2022/1334081.
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For many years, cellular manufacturing has been implemented by owners of manufacturing units. Furthermore, the increasing importance of sustainable development has led manufacturers and managers to consider the concepts of sustainable manufacturing. Sustainable manufacturing includes three components: economic, environmental, and social responsibility. Many research and studies have been conducted in the field of cellular manufacturing, and also in most studies, only the economic component or at most two components of sustainable manufacturing have been taken into account. With increasing concerns about global warming, environmental issues have become particularly important in the production of products and goods. On the other hand, customer satisfaction as one of the aspects of social responsibility is of significant importance. In this research, we put the sustainable manufacturing system in the dynamic cellular manufacturing system under uncertainty (fuzzy parameters). A multiobjective sustainable mathematical model with objective functions of minimizing costs minimizing CO2 emissions and minimizing product shortages (customer satisfaction) was proposed. In order to confirm the validity and accuracy of the proposed model, a small example was solved in GAMS software with CPLEX solver and epsilon constraint method, and its basic variables were investigated. Then, due to the high complexity of the proposed cellular manufacturing model, two meta-heuristic algorithms NSGA-II and MOGWO were used to solve larger problems in MATLAB software. To compare the performance of the two proposed algorithms, ten problems with different dimensions were designed and then the two algorithms were compared with each other based on several performance evaluation indicators. Also, in order to investigate the significance of the difference between the two algorithms based on each index, a statistical analysis was carried out by Minitab software. Taguchi method was also used to adjust the parameters of both algorithms. Based on the analytic results and statistical analysis, the MOGWO algorithm performed better than NSGA-II algorithm and the exact solution method, GAMS software.
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Maimori, Romi, Eliwatis Eliwatis, and Syafriwaldi Syafriwaldi. "Utilization of Information Communication Technology on Education and Social Change Of Village Community." Jurnal at-Taghyir: Jurnal Dakwah dan Pengembangan Masyarakat Desa 5, no. 1 (January 12, 2023): 157–78. http://dx.doi.org/10.24952/taghyir.v5i1.6011.
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Information and Communication Technology (ICT) changes people's lives and becomes a vital development tool, including in rural areas. ICT also provides positive and negative social change for rural communities in terms of social welfare, social and cultural ties. The purpose of this study was to get an overview of the use of ICT for social changes that occur in the community in Sungai Sirah village, Padang Pariaman Regency. The method used is a qualitative approach. The results of the study found that most rural communities already use ICT (cellular phones). Meanwhile, computers/laptops are still used by certain groups, such as village officials, youth organizations, teachers and students. Internet is still very limited in use due to limited access/network, expensive data packages and minimal skills. There are social changes in society, limited to ways of communicating, seeking/disseminating information and making work easier. While e-commerce activities (online buying and selling) that can improve the social welfare of the community do not yet exist. Aspects of individual social ties indicate that the need to communicate drives people to use ICT. However, direct/face-to-face communication is still the main thing. Village communities are also less worried about cultural changes due to the negative impacts of using ICT. Because the norms developed in the village are still firmly held by the community. However, filters and anticipation of the negative impacts of using ICTs must still be prepared, especially in schools
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Messina, Concetta Maria, Manfredi Madia, Simona Manuguerra, Cristobal Espinosa-Ruiz, María Angeles Esteban, and Andrea Santulli. "Dietary Inclusion of Halobacterium salinarum Modulates Growth Performances and Immune Responses in Farmed Gilthead Seabream (Sparus aurata L.)." Animals 13, no. 17 (August 29, 2023): 2743. http://dx.doi.org/10.3390/ani13172743.
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The use of natural immunostimulants is considered the most promising alternative to promote fish health, productive performance and quality, increasing the aquaculture profitability, sustainability and social acceptance. The purpose of this study was to evaluate the effect of the integration of a potential probiotic strain, Halobacterium salinarum, belonging to the Archaea domain, in the formulated diets of farmed gilthead seabream (Sparus aurata L.) in terms of growth performances and immunity responses. The experiment was set up to test two different levels of inclusion of the bacteria in the diet: 0.05% (D1) and 0.1% (D2). The effects on fish growth performances; humoral (peroxidase, protease, antiprotease and IgM levels) and cellular immunity parameters (phagocytosis, respiratory burst and myeloperoxidase), along with bactericidal activity, were evaluated after 15 and 30 days of experimental feeding. The obtained results showed that the inclusion of H. salinarum at the highest concentration (D2 0.1%) improved growth performances, bactericidal activity against Vibrio anguillarum and some parameters related both to the humoral and cellular immune response, suggesting exploring other aspects of welfare in view of future supplementations of this probiotic strain in the diet of S. aurata.
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Williams, Robin S. B., Jonathan R. Chubb, Robert Insall, Jason S. King, Catherine J. Pears, Elinor Thompson, and Cornelis J. Weijer. "Moving the Research Forward: The Best of British Biology Using the Tractable Model System Dictyostelium discoideum." Cells 10, no. 11 (November 5, 2021): 3036. http://dx.doi.org/10.3390/cells10113036.
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The social amoeba Dictyostelium discoideum provides an excellent model for research across a broad range of disciplines within biology. The organism diverged from the plant, yeast, fungi and animal kingdoms around 1 billion years ago but retains common aspects found in these kingdoms. Dictyostelium has a low level of genetic complexity and provides a range of molecular, cellular, biochemical and developmental biology experimental techniques, enabling multidisciplinary studies to be carried out in a wide range of areas, leading to research breakthroughs. Numerous laboratories within the United Kingdom employ Dictyostelium as their core research model. This review introduces Dictyostelium and then highlights research from several leading British research laboratories, covering their distinct areas of research, the benefits of using the model, and the breakthroughs that have arisen due to the use of Dictyostelium as a tractable model system.
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Tataryan, Karine. "P4-179: THE QUALITY OF LIFE AND SOME ASPECTS OF SOCIAL FUNCTIONING OF ELDERLY PEOPLE WITH MENTAL DISORDER." Alzheimer's & Dementia 14, no. 7S_Part_29 (July 1, 2006): P1507—P1508. http://dx.doi.org/10.1016/j.jalz.2018.06.2584.
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Bamicha, Victoria, and Yolanda Salapata. "LLLT applications may enhance ASD aspects related to disturbances in the gut microbiome, mitochondrial activity, and neural network function." Brazilian Journal of Science 3, no. 1 (August 25, 2023): 140–58. http://dx.doi.org/10.14295/bjs.v3i1.457.
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Autism Spectrum Disorder constitutes a complex, elaborate, and diverse condition at a developmental, biological, and neurophysiological level. It is recognized primarily by the behavioral manifestations of the individual in communication, social interaction, and by extension in his cognitive development and adaptation to society as a whole. A wide range of studies have linked the pathophysiology of autism to dysfunctional elements in the development and function of mitochondria, cells, neurons, and the gastrointestinal microbiome. Low Light Laser Therapy (LLLT) is an innovative, emerging, non-invasive treatment method. It utilizes low levels of red light/near-infrared light positively affecting biological and pathological processes of the body by enhancing cellular, mitochondrial stimulation, neurogenesis, synaptogenesis, and immune system development, regulating the gut microbiome's function. The retrospective literature review focuses on the possibility of effective use of the method in autism. According to the literature, LLLT does not have many applications in patients with ASD and is still in the early stages of its use in the disorder. However, the results of the studies highlight its therapeutic effect in several areas related to the disease, pointing out that it is a promising therapeutic approach for the evolution of autism in the future.
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Vaessen, Maarten J., Etienne Abassi, Maurizio Mancini, Antonio Camurri, and Beatrice de Gelder. "Computational Feature Analysis of Body Movements Reveals Hierarchical Brain Organization." Cerebral Cortex 29, no. 8 (October 1, 2018): 3551–60. http://dx.doi.org/10.1093/cercor/bhy228.
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Abstract Social species spend considerable time observing the body movements of others to understand their actions, predict their emotions, watch their games, or enjoy their dance movements. Given the important information obtained from body movements, we still know surprisingly little about the details of brain mechanisms underlying movement perception. In this fMRI study, we investigated the relations between movement features obtained from automated computational analyses of video clips and the corresponding brain activity. Our results show that low-level computational features map to specific brain areas related to early visual- and motion-sensitive regions, while mid-level computational features are related to dynamic aspects of posture encoded in occipital–temporal cortex, posterior superior temporal sulcus and superior parietal lobe. Furthermore, behavioral features obtained from subjective ratings correlated with activity in higher action observation regions. Our computational feature-based analysis suggests that the neural mechanism of movement encoding is organized in the brain not so much by semantic categories than by feature statistics of the body movements.
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Yashin, Anatoliy, Deqing Wu, Konstantin Arbeev, Olivia Bagley, Igor Akushevich, Arseniy Yashkin, Matt Duan, and Svetlana Ukraintseva. "The Interplay Between Stress Related Genes and Its Role in Human Longevity: Insights for Translational Studies." Innovation in Aging 5, Supplement_1 (December 1, 2021): 668. http://dx.doi.org/10.1093/geroni/igab046.2519.
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Abstract Human lifespan is a multifactorial trait resulted from complicated interplay among many genetic and environmental factors. Despite substantial progress in clarifying many aspects of lifespan’ variability the mechanism of its multifactorial regulation remains unclear. In this paper we investigate the role of genes from integrated stress response (ISR) pathway in such regulation. Experimental studies showed that persistent cellular stress may result in cellular senescence (for proliferating cells), or in apoptosis (for post-mitotic cells) which may affect health and lifespan in laboratory animals. These studies also showed which ISR genes are likely to interplay to produce joint effects on these traits. Note that in humans, the interplay between these genes does not necessarily influence these traits. This is because biological mechanisms regulating these traits in laboratory animals and humans may differ. This means that, when possible, the experimentally detected connections promising for human applications, should be verified using available human data before their testing in expensive clinical trials. In this paper we used HRS data to test connection between SNPs from the EIF2AK4 gene that senses cellular stress signals and the DDIT3 gene from the apoptosis regulation part of the ISR. We found genome wide significant associations between interacting SNPs from these genes and longevity. This result shows that available human data may be successfully used for making important steps in translation of experimental research findings towards their application in humans. Following this strategy may increase efficiency of clinical trials aiming to find appropriate medications to promote human health and longevity.
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Rinderknecht, Helen, Alana Mayer, Tina Histing, Sabrina Ehnert, and Andreas Nüssler. "Herbal Extracts of Ginseng and Maqui Berry Show Only Minimal Effects on an In Vitro Model of Early Fracture Repair of Smokers." Foods 12, no. 15 (August 4, 2023): 2960. http://dx.doi.org/10.3390/foods12152960.
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Smoking is a major risk factor for delayed fracture healing, affecting several aspects of early fracture repair, including inflammation, osteogenesis, and angiogenesis. Panax ginseng (GE) and maqui berry extract (MBE) were shown in our previous studies to reduce smoke-induced cellular damage in late bone-healing in vitro models. We aimed here to analyze their effects on the early fracture repair of smokers in a 3D co-culture model of fracture hematomas and endothelial cells. Both extracts did not alter the cellular viability at concentrations of up to 100 µg/mL. In early fracture repair in vitro, they were unable to reduce smoking-induced inflammation and induce osteo- or chondrogenicity. Regarding angiogenesis, smoking-induced stress in HUVECs could not be counteracted by both extracts. Furthermore, smoking-impaired tube formation was not restored by GE but was harmed by MBE. However, GE promoted angiogenesis initiation under smoking conditions via the Angpt/Tie2 axis. To summarize, cigarette smoking strikingly affected early fracture healing processes in vitro, but herbal extracts at the applied doses had only a limited effect. Since both extracts were shown before to be very effective in later stages of fracture healing, our data suggest that their early use immediately after fracture does not appear to negatively impact later beneficial effects.
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Labib Eid, Niveen, and Anton Robert Sabella. "A fresh approach to corporate social responsibility (CSR): partnerships between businesses and non-profit sectors." Corporate Governance 14, no. 3 (May 27, 2014): 352–62. http://dx.doi.org/10.1108/cg-01-2013-0011.
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Purpose – The aim of this paper is to offer a new conceptualisation on partnership emergence and dynamism between the business sector and the non-governmental organization (NGO) sector from a corporate social responsibility perspective. More specifically, the paper intends to examine partnering behaviour and management from a socio-political standpoint. Design/methodology/approach – The case study approach used in the study utilised data from eight in-depth, semi-structured interviews, with managers from the business and NGO sectors engaged in a large-scale partnership between a Palestinian Cellular Corporation and an NGO. Interview transcripts were analysed using content and narrative analyses. Findings to be presented include reciprocity, corporate constitutionalism and utilitarianism. Findings – The results found in this paper show that partnership has social, political, and ethical dimensions in support of the theoretical framework developed for this paper. More specifically, the results show that the studied partnership is an emergent process, fundamentally concerned with self-efficacy over community welfare, as well as being driven by individual organisational goals. Originality/value – This paper sheds light on certain aspects of partnership that are often overlooked in mainstream research. It does not only highlight the multifaceted dimensions of partnering but also discusses how partnership can be envisioned and practised as inter-organisational relationships. It stimulates a pragmatic understanding of partnership nature and management showing that partnership emergence, direction and sustainability are conditioned by the stakeholders’ socio-political and ethical practices.