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Relevant bibliographies by topics / Cellular signal transduction / Dissertations / Theses

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Dissertations / Theses on the topic 'Cellular signal transduction'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 July 2024

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1

Pat, Betty Kila. "Signal transduction pathways in renal fibrosis /." St. Lucia, Qld, 2003. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17739.pdf.

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2

Haugh, Jason Michael 1972. "Cellular compartmentation effects in receptor-mediated signal transduction." Thesis, Massachusetts Institute of Technology, 1999. http://hdl.handle.net/1721.1/85364.

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3

Leahy, Rachel A. "Signal Transduction and Cellular Differentiation in Airway Epithelium." Kent State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=kent1352673026.

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4

Kim, Hyun Ji. "Development and signal transduction in Dictyostelium." Thesis, University of Oxford, 1999. http://ora.ox.ac.uk/objects/uuid:4ed80c6e-adc8-46d6-aeaf-c853cef7af77.

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Dictyostelium, is a simple eukaryote that multiplies as separate amoebae. However when nutrients are no longer available it embarks on a developmental programme in which the amoebae collect together by chemotaxis and the resulting aggregates eventually transform into fruiting bodies consisting of a cluster of spores held up on a cellular stalk. The entire process of development normally takes about 24 hours. However there are mutants, termed rapidly developing mutants (rde) which complete development in about two-thirds of this time. RdeA null mutants have been reported to have elevated levels

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5

Chang, Wen-Tsan. "Molecular studies of signal transduction and development." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360212.

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6

Brownlie, Zoe. "Regulation of signal transduction by RGS4." Connect to e-thesis, 2007. http://theses.gla.ac.uk/124/.

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Thesis (Ph.D.) - University of Glasgow, 2007.<br>Ph.D. thesis submitted to the Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, 2007. Includes bibliographical references.

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7

Gammon, Benjamin Matthew. "Signal transduction in the cellular slime mould Dictyostelium discoideum." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279872.

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8

Manne, Bhanu Kanth. "CLEC-2 SIGNAL TRANSDUCTION IN PLATELET ACTIVATION." Diss., Temple University Libraries, 2015. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/340495.

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Physiology<br>Ph.D.<br>Platelets are involved in many processes ranging from fighting microbial infections and triggering inflammation to promoting tumor angiogenesis and metastasis. Nevertheless, the primary physiological function of platelets is to act as essential mediators in maintaining homeostasis of the circulatory system by forming hemostatic thrombi that prevent blood loss and maintain vascular integrity. CLEC-2 is a C-type lectin-like receptor that is highly expressed in platelets and lesser extent, in other cell types such as activated dendritic cells and B cells. Rhodocytin was the

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9

Hung, Hiu Wai. "Signal transduction mechanism in xenopus presynaptic differentiation /." View Abstract or Full-Text, 2003. http://library.ust.hk/cgi/db/thesis.pl?BIOL%202003%20HUNG.

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10

Gong, Yunchen 1965. "Analyses of alternative cell signal transduction pathways." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=85552.

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Living cells keep sensing the changes in their environments, mostly, via cell surface receptors for different ligands. Attachment-dependent cells are sensitive to alterations in extracellular matrix (ECM). ECM is not only required for cell survival, but also prerequisite for epidermal growth factor (EGF) to stimulate cell proliferation. The receptors for the majority of ECM components are integrins and the receptor for EGF is EGF receptor (EGFR). When bound by their ligands, integrins and EGFR induce signal transduction cascades composed of alternative pathways. A quantitative assessmen

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11

Ulrich, Luke. "Comparative Genomics of Microbial Signal Transduction." Diss., Georgia Institute of Technology, 2005. http://hdl.handle.net/1853/7632.

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High-throughput genome processing, sophisticated protein sequence analysis, programming, and information management were used to achieve two major advances in the comparative genomics of microbial signal transduction. First, an integrated and flexible bioinformatics platform and the Microbial Signal Transduction database (MiST) were developed, which facilitated the genome-wide analysis of bacterial signal transduction. This platform was used successfully for the high-throughput identification and classification of signal transduction proteins in more than 300 archaeal and bacterial organisms.

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12

Wong, Wai-lap. "Signal transduction pathways of ret receptor tuyrosine kinase." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22786478.

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13

王偉立 and Wai-lap Wong. "Signal transduction pathways of ret receptor tuyrosine kinase." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31225354.

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14

Roberts, Craig Dane. "cAMP Signaling in Chemosensory Transduction." Scholarly Repository, 2008. http://scholarlyrepository.miami.edu/oa_dissertations/161.

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cAMP is a second messenger in a variety of chemosensory receptors, including taste buds and glucose-sensitive pancreatic beta-cells. cAMP is modulated during taste transduction, yet the significance of cAMP changes and the taste cell types in which they occur (Type I glial-like; Type II Receptor; Type III Presynaptic) remain unclear. I developed techniques to image real-time changes in intracellular cAMP in taste cells using genetically-encoded cAMP reporters. This FRET-based reporter permits one to measure single-cell cAMP levels with excellent spatial and temporal resolution (Zaccolo & Pozza

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15

Richard, Jessica. "The two-component signal transduction systems of Pseudomonas aeruginosa." Thesis, Montana State University, 2008. http://etd.lib.montana.edu/etd/2008/richard/RichardJ0508.pdf.

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Two-component signal transduction systems are important components for bacteria, because they allow the bacteria to sense environmental conditions and rapidly adapt to changes in the environment. Two-component systems generally contain a sensor histidine kinase, which detects an environmental signal and responds by autophosphorylation at a histidine residue using ATP as the phosphate donor. The phosphate group is then transferred to an aspartate residue in the receiver domain of the second component, the response regulator, which in its activated form responds by stimulating or repressing gene

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16

Tsui, Michelle Grace, and 徐善婷. "PDZD2, a candidate for brachydactyly type A1, encodes a secreted protein that negatively modulates hedgehog signaling." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/209211.

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Hedgehog (Hh) is an important morphogen that dictates tissue patterning during embryonic development. Recent studies showed that mutation in Indian Hedgehog(IHH)resulted in Brachydactyly type A1(BDA1);however, the disease pathogenesis in patients without IHH mutation remained unknown. PDZD2 is a multi-PDZ domain-containing protein of unknown function in early development. Human PDZD2 is mapped to chromosome 5p13.2, which co-localizes with the disease-associated gene in a family of BDA1 patients, suggesting involvement of PDZD2 in limb development. In situ hybridization revealed that Pdzd2 was

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17

Wangorsch, Gaby Verfasser], and Thomas [Akademischer Betreuer] [Dandekar. "Mathematical modeling of cellular signal transduction / Gaby Wangorsch. Betreuer: Thomas Dandekar." Würzburg : Universität Würzburg, 2013. http://d-nb.info/1107217032/34.

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18

Pliego-Rivero, Francisco Bernardo. "Thy-1 : cellular compartmentalization during development and participation in signal transduction." Thesis, Open University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358073.

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19

Wangorsch, Gaby [Verfasser], and Thomas [Akademischer Betreuer] Dandekar. "Mathematical modeling of cellular signal transduction / Gaby Wangorsch. Betreuer: Thomas Dandekar." Würzburg : Universität Würzburg, 2013. http://d-nb.info/1107217032/34.

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20

Rogers, Laura Ann. "Membranes as a hub for cellular signaling /." Access full-text from WCMC, 2007. http://proquest.umi.com/pqdweb?did=1481668281&sid=2&Fmt=2&clientId=8424&RQT=309&VName=PQD.

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21

Madan, Namrata. "Role of Different Isoforms of Na/K-ATPase in Signal Transduction." University of Toledo Health Science Campus / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=mco1418318054.

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22

Braun, David Meyer. "Maize receptor-like protein kinase signal transduction and function /." free to MU campus, to others for purchase, 1997. http://wwwlib.umi.com/cr/mo/fullcit?p9841268.

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23

Joyce, Kevin Michael. "Cellular and genomic effects of long-wavelength laser irradiation." Thesis, University of Ulster, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267791.

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24

Liu, Wei. "Role of axin in TGF-[beta] signaling pathway and characterization of axin mutant proteins in axinF̳u̳ mice /." View abstract or full-text, 2006. http://library.ust.hk/cgi/db/thesis.pl?BICH%202006%20LIUW.

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25

Han, Shujie. "Regulation of phorbol ester-induced Ras/Raf/Erk signaling pathway in EL4 cells." Online access for everyone, 2008. http://www.dissertations.wsu.edu/Dissertations/Summer2008/s_han_1062508.pdf.

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26

Wang, Kepeng. "The involvement of JAK2/STAT2/STAT3 in myogenic differentiation /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?BICH%202008%20WANGK.

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27

Chan, Yuen-yee Kathy. "Functional segregation of the highly conserved basic motifs within the third endoloop of the human secretin receptor /." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23621473.

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28

Kallenberger, Stefan M. [Verfasser], and Roland [Akademischer Betreuer] Eils. "Variability in cellular signal transduction networks / Stefan Matthias Kallenberger ; Betreuer: Roland Eils." Heidelberg : Universitätsbibliothek Heidelberg, 2014. http://d-nb.info/1177810905/34.

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29

Knapp, Bettina, and Lars Kaderali. "Reconstruction of Cellular Signal Transduction Networks Using Perturbation Assays and Linear Programming." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-127239.

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Perturbation experiments for example using RNA interference (RNAi) offer an attractive way to elucidate gene function in a high throughput fashion. The placement of hit genes in their functional context and the inference of underlying networks from such data, however, are challenging tasks. One of the problems in network inference is the exponential number of possible network topologies for a given number of genes. Here, we introduce a novel mathematical approach to address this question. We formulate network inference as a linear optimization problem, which can be solved efficiently even for

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30

Knapp, Bettina, and Lars Kaderali. "Reconstruction of Cellular Signal Transduction Networks Using Perturbation Assays and Linear Programming." Public Library of Science, 2013. https://tud.qucosa.de/id/qucosa%3A27289.

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Perturbation experiments for example using RNA interference (RNAi) offer an attractive way to elucidate gene function in a high throughput fashion. The placement of hit genes in their functional context and the inference of underlying networks from such data, however, are challenging tasks. One of the problems in network inference is the exponential number of possible network topologies for a given number of genes. Here, we introduce a novel mathematical approach to address this question. We formulate network inference as a linear optimization problem, which can be solved efficiently even for

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31

Hartgraves, Morri D. "Carbachol- and ACPD-Induced Phosphoinositide Responses in the Developing Rat Neocortex." Thesis, University of North Texas, 2000. https://digital.library.unt.edu/ark:/67531/metadc2640/.

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Signal transduction via the phosphoinositide (PI) second messenger system has key roles in the development and plasticity of the neocortex. The present study localized PI responses to individual cortical layers in slices of developing rat somatosensory cortex. The acetylcholine agonist carbachol and the glutamate agonist trans-1-amino-1,3-cyclopentanedicarboxylic acid (ACPD) were used to stimulate PI turnover. The PI responses were compared to the distribution of the corresponding PI-linked receptors in order to investigate the regional ontogeny of PI coupling to receptors in relation to neura

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32

Harding, Angus Silas. "A biochemical analysis of the MAP kinase pathway in mammalian cells /." A biochemical analysis of the MAP kinase pathway in mammalian cellsRead the abstract of the thesis, 2003. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17885.pdf.

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33

Lee, Tae Weon. "Regulation of expression of signal transduction cascade elements by G-protein coupled receptors." Thesis, University of Glasgow, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321070.

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34

Hudson, Christine Cecilia. "Isolation of signal transduction inhibitors by bioassay-directed fractionation of plant extracts." Diss., Georgia Institute of Technology, 1996. http://hdl.handle.net/1853/30636.

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35

Nikolaou, Elissavet. "Phylogenetic diversity of fungal stress signaling pathways." Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources, 2008. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=24849.

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36

Keane, John F. "A framework for molecular signal processing and detection in biological cells /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/6126.

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37

Miljan, Erik Armand Jaan. "Molecular and cellular characterization of ganglioside-stimulated protein kinase." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B29957618.

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38

Mayeenuddin, Linnia H. "Modulation of PTH-mediated signal transduction in osteoblasts by factors regulating cellular growth." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ28803.pdf.

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39

Small, Nadine Veronica. "Mechanism of signal transduction for chemotaxis of the cellular slime mould Dictyostelium discoideum." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.315786.

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40

Chahal, Manpreet Singh. "Roles for PLD2 in growth factor-mediated signal transduction in EL4 lymphoma cells." Pullman, Wash. : Washington State University, 2008. http://www.dissertations.wsu.edu/Dissertations/Fall2008/m_chahal_080808.pdf.

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Thesis (Ph. D.)--Washington State University, December 2008.<br>Title from PDF title page (viewed on Oct. 22, 2009). "Pharmacology/Toxicology Graduate Program." Includes bibliographical references (p. 90-97).

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41

Rentel, Maike Christina. "Signal transduction in response to active oxygen species in Arabidopsis thaliana." Thesis, University of Oxford, 2002. http://ora.ox.ac.uk/objects/uuid:5dc0b7f5-5aa9-4633-a8dd-89ca2dcb3982.

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Many environmental stresses result in increased generation of active oxygen species (AOS) in plant cells, leading to the induction of protective mechanisms. In this study, signalling components linking AOS perception to downstream responses were examined, with particular emphasis on H<sub>2</sub>O<sub>2</sub> signalling. All AOS investigated had an early [Ca<sup>2+</sup>]<sub>cyt</sub> peak in common, but differed in other aspects of their Ca<sup>2+</sup> signatures, indicating that the plant is able to discriminate between different types of AOS. An early event in AOS signal transduction may

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42

Cao, Yang. "Macromolecular crowding effects on the activity of the extracellular signal regulated kinase 2 /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?CHEM%202008%20CAO.

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43

Yu, Lu. "Multiple signaling pathways cooperate to activate skeletal muscle differentiation /." View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?BICH%202005%20YU.

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44

Xu, Weiguang. "Solution structure of [Alpha]-syntrophin PH-PDZ tandem domain /." View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?BICH%202005%20XU.

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45

Zhou, Liying. "Studying the mitochondria-dependent apoptotic signaling pathway in mammalian cells /." View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?BIOL%202005%20ZHOU.

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46

Ma, Chun-Wai. "Aboav-Weaire law in complex network and its applications in bioinformatics /." View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?PHYS%202005%20MA.

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47

Jamie, Hajierah. "Possible crosstalk between signal transduction pathways in the induction of differentiation in HT-29 cells." Thesis, University of Port Elizabeth, 2000. http://hdl.handle.net/10948/d1019684.

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The investigation into the mechanisms by which compounds such as butyrate induce differentiation in HT-29 cells, is lacking. The colonic carcinoma cell line, HT-29, undergoes differentiation induction in the presence of butyrate and acetoacetate. The Caco-2 cell line spontaneously differentiates on contact inhibition. In this study, a signal transduction pathway involving ATP, cAMP, Ca2+ and the transcriptional factor CREB was investigated following suggestions that the energy state of the cell and diffferentiation are linked. The activity of the MAP kinase cascade, including possible crosstal

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48

Geng, Hao. "ResDE-dependent transcriptional control in response to oxygen limitation /." Full text open access at:, 2007. http://content.ohsu.edu/u?/etd,256.

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49

Chan, Yuen-yee Kathy, and 陳婉儀. "Functional segregation of the highly conserved basic motifs within thethird endoloop of the human secretin receptor." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B3124290X.

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50

Chiu, Yung-tuen, and 趙容端. "Studying the role of androgen receptor signaling in the development, progression and therapeutic approach of prostate cancer." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B4559692X.

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