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Dissertations / Theses on the topic 'Cell uptake'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Meylan-Gonin, Carole. "Enhanced cell uptake of cell penetrating peptide modified liposomes diploma thesis /." Zürich : ETH, Eidgenössische Technische Hochschule Zürich, Departement Angewandte Biowissenschaften, Institut für Pharmazeutische Wissenschaften, 2003. http://e-collection.ethbib.ethz.ch/show?type=dipl&nr=111.

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2

Holm, Tina. "Cell-penetrating peptides : Uptake, stability and biological activity." Doctoral thesis, Stockholms universitet, Institutionen för neurokemi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-55664.

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Cell-penetrating peptides (CPPs) have emerged as a group of remarkable delivery vectors for various hydrophilic macromolecules, otherwise excluded from cells due to the protective plasma membrane. Unbiased conclusions regarding e.g. uptake mechanism, intracellular distribution and cargo delivery efficacy is complicated by the use of different methodological parameters by different laboratories. The first paper in this thesis introduced unifying protocols enabling comparison of results from different research groups. One of these methods, HPLC, was used in paper II to investigate CPP uptake and

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3

Bugg, Trevor. "Uptake and efflux of PAHs across bacterial cell membranes." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0008/MQ60096.pdf.

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4

Varzakas, Theodore Haralambous. "Uptake of cell-wall degrading enzymes by soybean preparations." Thesis, University of Reading, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.387769.

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5

Turner, Mark C. "Cell culture models of insulin signalling and glucose uptake." Thesis, Loughborough University, 2015. https://dspace.lboro.ac.uk/2134/19582.

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Insulin maintains glucose homeostasis through its binding of the insulin receptor and activation of the insulin signalling cascade in insulin sensitive tissues. Skeletal muscle is a major endocrine organ, and is responsible for the majority of post-prandial glucose disposal. The maintenance of glucose homeostasis is a delicate balance and impairments in glucose disposal can have significant physiological effects, resulting in the onset of metabolic diseases such as diabetes mellitus. Insulin stimulated glucose uptake involves a number of signalling proteins to enable uptake to occur. In order

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6

Staley, Ben Paul. "Quantification of cell penetrating peptide uptake by fluorescent techniques." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/quantification-of-cell-penetrating-peptide-uptake-by-fluorescent-techniques(529b93cb-3550-437a-959a-4eb2eba60da3).html.

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Cell penetrating peptides have been the focus of drug delivery research for 15 years due to their apparent ability to deliver cargoes inside cells more readily than many other carriers. Using two of the most commonly studied peptides (tat47-57 and R9), the present study differs from previous work by deliberately choosing to observe uptake with lower peptide concentrations closer to potential therapeutic doses, and by implementing raster image correlation spectroscopy (RICS) on a commercial microscope to quantify uptake in parallel to other techniques such as fluorescence correlation spectrosco

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7

Twomey, Ciara. "Ribozyme delivery into the 32Db3a2 cell line." Thesis, University of East Anglia, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323247.

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8

PHADNGAM, SURATCHANEE. "In Cell Imaging Techniques to Monitor Glucose Uptake, Cell Migration, and Vesicular Traffic: A Functional Study in Cancer Cells." Doctoral thesis, Università del Piemonte Orientale, 2016. http://hdl.handle.net/11579/115172.

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9

Ji, Yu. "Characterisation of red blood cell Phagocytosis and assessment of nanoparticle uptake by Monocytic cells." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/208148/1/Yu_Ji_Thesis.pdf.

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This thesis explored interactions between monocytes and IgG sensitised RBCs as well as synthetic particles for clinical and biomedical application. A monocyte monolayer assay was developed for Red Cell Reference Laboratory in Australia to predict transfusion outcomes, and mechanism and immune modulation associated with this assay and biomedical potential of polystyrene particles were explored using genetic and biological studies. The results obtained will contribute to improved transfusion safety and patient management and contribute knowledge in the fields of biomedical research using nanomat

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10

Chernogubova, Ekaterina. "Adrenergic stimulation of glucose uptake in brown adipocytes." Doctoral thesis, Stockholm : The Wenner-Gren institute, Stockholm university, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-549.

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11

Muñoz-Alarcón, Andrés. "Cell-penetrating peptides and oligonucleotides : Design, uptake and therapeutic applications." Doctoral thesis, Stockholms universitet, Institutionen för neurokemi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-116049.

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Regulation of biological processes through the use of genetic elements is a central part of biological research and also holds great promise for future therapeutic applications. Oligonucleotides comprise a class of versatile biomolecules capable of modulating gene regulation. Gene therapy, the concept of introducing genetic elements in order to treat disease, presents a promising therapeutic strategy based on such macromolecular agents. Applications involving charged macromolecules such as nucleic acids require the development of the active pharmaceutical ingredient as well as efficient means

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12

Attfield, Kathrine Elizabeth. "The effect of manipulating apoptotic cell uptake on their immunogenicity." Thesis, University of Southampton, 2009. https://eprints.soton.ac.uk/72701/.

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Failure of the immune system to differentiate between apoptotic tumour cells and cells rendered apoptotic as part of homeostasis prevents a successful response being mounted against tumours. Apoptotic cells are cleared rapidly by professional phagocytes thus preventing the release of potentially inflammatory or immunogenic material into the surrounding environment. In addition, macrophages release immuno-suppressive cytokines such as tumour growth factor β (TGF-β) and interleukin-10 (IL-10) that dampen the initiation of cytotoxic T cell (CTL) immunity and render T cells tolerant. It was hypoth

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13

Sasso, L. "In vitro uptake studies of cell targeting agents and nanoparticles." Thesis, University of Nottingham, 2015. http://eprints.nottingham.ac.uk/28529/.

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Recent progress in synthetic chemistry has enabled the preparation of new highly-defined polymers that exhibit changes in their structure in response to environmental changes. These responsive nanomaterials may be desirable as carriers of drugs to deliver at the cellular and sub-cellular level. However, the endocytic pathways used by these nanoparticles to access cells must be defined. Carboxylated polystyrene beads (C-PB) of 50 and 100 nm size were chosen as ‘model’ nanomedicines and their route of uptake into cells characterised and compared to thermoresponsive PLGA-b-(PEGMA-co-PPGMA) and PL

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14

Helmfors, Henrik. "Cell-penetrating peptides : Uptake mechanism and the role of receptors." Doctoral thesis, Stockholms universitet, Institutionen för neurokemi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-120832.

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Genes are the major regulators of biological processes in every living thing. Problems with gene regulation can cause serious problems for the organism; for example, most cancers have some kind of genetic component. Regulation of biological processes using oligonucleotides can potentially be a therapy for any ailment, not just cancer. The problem so far has been that the targets for oligonucleotide-based therapies all reside on the inside of cells, because the cellular plasma membrane is normally impermeable to large and charged molecules (such as oligonucleotides) a delivery method is needed.

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15

Mahadevan, Swarna. "Single Cell Analysis of the Effect on Cancer Cell Phenotype of Uptake of Fibroblast Contents by Cell- Projection Pumping." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/29775.

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Earlier work showed transfer of cytoplasm between co-cultured cancer cells and fibroblasts. Cancer cell changed upon uptake of fibroblast contents, with altered morphology and increased cell volume, internal cell complexity and cell migration velocity. The biomechanical basis for transfer was revealed as hydrodynamic, and was termed 'cell-projection pumping'. An important role for cell-projection pumping in driving cancer cell diversity and disease progression was proposed. Assays used in earlier studies averaged the response of many thousands of cancer cells. This may have obscured im

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16

Martínez, Torró Carlos. "Transcriptional Regulation of Cell Division and Metal Uptake in Mycoplasma genitalium." Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/671599.

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Mycoplasma genitalium és un patogen humà que es transmet sexualment i causant d’uretritis, cervicitis i inflamació pelviana. Conté el genoma més petit de qualsevol microorganisme capaç d’autoreplicar-se, amb només 580 kb i 500 gens que codifiquen per proteïnes. L’interès en aquest patogen ha anat augmentat durant els darrers anys degut a la seva cada cop major prevalença i l’aparició de soques resistents a múltiples antibiòtics. En aquesta tesi doctoral, analitzem en detall la divisió cel·lular d’aquest microorganisme, així com la seva resposta a l’absència de metalls. Pel que fa a la divisió,

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17

Tünnemann, Gisela. "Toxicity, uptake and applications of intracellular delivery by cell penetrating peptides." Diss., lmu, 2009. http://nbn-resolving.de/urn:nbn:de:bvb:19-105432.

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18

Ezzat, Kariem. "Cell-penetrating peptides; chemical modification, mechanism of uptake and formulation development." Doctoral thesis, Stockholms universitet, Institutionen för neurokemi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-75537.

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Gene therapy holds the promise of revolutionizing the way we treat diseases. By using recombinant DNA and oligonucleotides (ONs), gene functions can be restored, altered or silenced according to the therapeutic need. However, gene therapy approaches require the delivery of large and charged nucleic acid-based molecules to their intracellular targets across the plasma membrane, which is inherently impermeable to such molecules. In this thesis, two chemically modified cell-penetrating peptides (CPPs) that have superior delivery properties for several nucleic acid-based therapeutics are developed

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19

Harrison, J. G. "Studies on the cell uptake and hybridisation properties of oligonucleotide derivatives." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603788.

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A series of 3'-linked conjugates between an oligodeoxyribonucleotide 13mer and cholic, folic, lipoic and pantothenic acids, cholesterol, vitamin E and a viral fusion peptide have been prepared in an attempt to enhance the cellular uptake properties of the nucleic acid. It was envisaged that the 4 biological acids may improve the cellular uptake of the oligonucleotide through natural receptor-mediated uptake mechanisms, whilst cholesterol, vitamin E and the fusion peptide may enhance interaction of the conjugate with cellular membranes. In the course of preparing conjugates involving cholic, fo

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20

Chen, Xuguang. "Cellular Uptake of DNA Nanoparticles and Regulation of Cell Surface Nucleolin." Case Western Reserve University School of Graduate Studies / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1244145515.

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21

Patel, B. "A study into vanadium speciation : Methodology, characterisation, and identification." Thesis, University of Greenwich, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234785.

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22

Bergsmedh, Anna. "Horizontal gene transfer by uptake of apoptotic bodies /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-713-4.

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23

Graf, Franziska. "DNA Origami Nanoparticles for Cell Delivery: The Effect of Shape and Surface Functionalization on Cell Internalization." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10259.

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An outstanding challenge in modern medicine is the safe and efficient delivery of drugs. One approach to improve drug delivery yield and increase specificity towards diseased cells, is to employ a drug carrier to facilitate transport. Promising steps towards developing such a carrier have been taken by the nascent field of nanomedicine: nanometer-sized particles designed to evade premature excretion, non-specific absorption, and the body’s immune response, can reduce undesired drug loss, while also increasing specific drug uptake into diseased cells through targeting surface modifications. How

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24

Wells, J. M. "The role of the cell wall in metal uptake, redistribution and tolerance in the moss Rhytidiadelphus squarrosus." Thesis, University of Bristol, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384440.

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25

Chindera, Kantaraja. "Cell uptake properties of Polyhexamethylene Biguanide (PHMB) and applications in intracellular delivery." Thesis, Royal Veterinary College (University of London), 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618319.

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26

Ferruzzi, Mario G. "Digestive stability, human intestinal cell uptake, and bioactivity of dietary chlorophyll derivatives /." The Ohio State University, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=osu1486394475978215.

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27

Mei, Hong. "NB1-C16-Insulin incorporated liposomal anticancer agents : formulation, cell uptake and cytotoxicity /." The Ohio State University, 1999. http://rave.ohiolink.edu/etdc/view?acc_num=osu1488187049541811.

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28

Redgate, Christopher Patrick Houtby. "Cell penetrating guanidinoglycosides design, synthesis, and uptake of multivalent guanidinylated Neomycin B /." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p1465085.

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Thesis (M.S.)--University of California, San Diego, 2009.<br>Title from first page of PDF file (viewed June 22, 2009). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 52-62).

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29

Tosatto, Anna. "Role of mithocondrial Ca2+ uptake in breast cancer cell migration and invasiveness." Doctoral thesis, Università degli studi di Padova, 2015. http://hdl.handle.net/11577/3424008.

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Mitochondrial Ca2+ uptake regulates cellular energetic by triggering ATP synthesis. At the same time, Ca2+mit acts as key controller of both cell metabolism and fate. Indeed, a decrease in ATP production elicits autophagy induction, while Ca2+ overload causes organelle dysfunction and release of caspase cofactors. Several pathological conditions, including tumor formation and progression, are directly related to mitochondrial dysfunctions, and reprogramming of mitochondrial metabolism is now considered as an emerging hallmark of cancer. Indeed, even in the presence of oxygen, cancer cells limi

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30

FENG, YIHONG. "Controllable cell delivery and chromatin structure observation using DNA nanotechnology." Kyoto University, 2020. http://hdl.handle.net/2433/258987.

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31

Meyer, Jason M. "A Novel Selective Lipid Uptake Pathway Contributing to LDL-Induced Macrophage Foam Cell Formation." UKnowledge, 2013. http://uknowledge.uky.edu/biochem_etds/11.

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Atherosclerosis is a disease characterized by cholesterol-rich plaques within the intima of medium and large arteries. Cholesterol deposition is thought to occur by infiltration of low-density lipoprotein (LDL) into lesions followed by uptake into macrophages, generating lipid-loaded “foam cells.” Foam cells can also be generated in vitro by treatment of macrophages with LDL or oxidized LDL (oxLDL). The purpose of the current investigation was to determine the contribution of selective cholesteryl ester (CE) uptake versus whole-particle uptake during LDL-induced foam cell formation in cultured

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32

BUSTI, STEFANO. "Glucose and regulation of cell cycle in saccharomyces cerevisiae: analisys of mutans impaired in sugar uptake mechanisms." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2009. http://hdl.handle.net/10281/7482.

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Glucose and regulation of cell cycle in S. cerevisiae: analysis of mutants impaired in sugar uptake mechanisms Requisito fondamentale per la sopravvivenza di microrganismi a vita libera come il lievito S. cerevisiae è la capacità di regolare il proprio metabolismo e la progressione del ciclo cellulare in modo tale che la crescita sia rapida in presenza di abbondanti nutrienti e si arresti all’esaurirsi degli stessi. Perché questo sia possibile, nutrienti come il glucosio devono generare segnali che vengano recepiti ed elaborati dal complesso macchinario che governa il ciclo cellulare. S. cer

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33

EL, Andaloussi Samir. "Vectorization of oligonucleotides with cell-penetrating peptides : Characterization of uptake mechanisms and cytotoxicity." Doctoral thesis, Stockholms universitet, Institutionen för neurokemi, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-7167.

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The hydrophobic plasma membrane constitutes an indispensable barrier for cells in living animals. Albeit being pivotal for the maintenance of cells, the inability to cross the plasma membrane is still one of the major obstacles to overcome in order to progress current drug development. A group of substances, with restricted access to the interior of cells, which has shown great promise for future clinical use is oligonucleotides that are exploited to interfere with gene expression. Short interfering RNAs that are utilized to confer gene silencing and splice correcting oligonucleotides, applied

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34

Kenigsberg, Rhoda Leah. "Catecholamine uptake and release in chromaffin cell cultures : a possible role for calmodulin." Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=72051.

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In view of calmodulin's widespread role in calcium-regulated processes, together with the requirement of Ca('2+) for chromaffin cell secretion, a possible role for calmodulin in translating the Ca('2+) signal for secretion is suggested.<br>Isolated bovine adrenal medullary cells were maintained in monolayer culture and their morphological and functional characteristics examined. The cultured chromaffin cell was found capable of accumulating exogenous amines via a high affinity uptake(,1)-like process which closely simulated the neuronal process in many respects but demonstrated neither stereo-

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35

Chabaud, Mélanie. "Cell migration and antigen uptake are two antagonistic functions that are coupled by Myosin II in dendritic cells." Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05T021.

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Les cellules dendritiques (DCs) patrouillent les tissus périphériques à la recherche de dangers potentiels en se déplaçant à travers les tissus et en incorporant de grande quantité de matériel extracellulaire. Cet événement précoce de la réponse immunitaire adaptative est susceptible de déterminer l'amplitude et la qualité de l'activation des lymphocytes T et B. De ce fait, les DCs pourraient avoir besoin d'orchestrer leur motilité et leur fonction de capture des antigènes afin d'initier un réponse immunitaire efficace et adaptée. Afin d'étudier les mécanismes responsables de l'optimisation de

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36

He, Lin. "Defining the role of the actin cytoskeleton in cellular uptake of cell penetrating peptides." Thesis, Cardiff University, 2016. http://orca.cf.ac.uk/94910/.

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The increased need for macromolecular therapeutics, such as proteins and nucleotides, to reach intracellular targets asks for more effective delivery vectors and a higher level of understanding of their mechanism of action. Cell Penetrating Peptides (CPPs) have been shown to deliver a range of macromolecules into cells either through direct plasma membrane translocation or by endocytosis. All known endocytic pathways involve cellcortex remodelling, a process shown to be regulated by reorganisation of the actin cytoskeleton. Links between actin remodelling and CPP uptake has been shown but more

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37

Greil, Christopher Scott. "ACUTE CELLULAR UPTAKE OF ABNORMAL PRION PROTEIN IS CELL TYPE AND SCRAPIE STRAIN INDEPENDENT." The University of Montana, 2008. http://etd.lib.umt.edu/theses/available/etd-09092008-155126/.

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<p>Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases that include Creutzfeldt-Jakob disease, bovine spongiform encephalopathy and sheep scrapie. TSE disease pathology and mechanisms within the central nervous system (CNS) of an infected host largely remains unclear. At the cellular level, the uptake of protease resistant prion protein (PrP-res), which strongly correlates with infectivity and is a valid marker for TSE infection, is one of the earliest events that must occur during TSE infection. Given the difficulty of clearly distinguishing input PrP-res fro

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38

DE, MARCHI Elena. "Mitochondrial calcium uptake and release mechanisms as key regulators of cell life or death." Doctoral thesis, Università degli studi di Ferrara, 2014. http://hdl.handle.net/11392/2388964.

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Mitochondria are cellular organelles that play a key role in several physiological processes, including cell proliferation, differentiation, cell death and the regulation of cellular calcium (Ca2+) homeostasis. Increases in mitochondrial Ca2+ activate several dehydrogenases and carriers, inducing enhance in the respiratory rate, H+ extrusion, and ATP production necessary for the correct energy state of the cell. The mitochondrial Ca2+ uptake and release mechanisms are based on the utilization of gated channels for Ca2+ uptake and exchangers for release that are dependent upon the negative mi

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39

Sharief, Mujataba Rahiman. "Regulation of Particle Uptake by PP2A/B56 and LKB1 in Dictyostelium Discoideum." FIU Digital Commons, 2016. http://digitalcommons.fiu.edu/etd/2539.

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Dictyostelium discoideum is a soil dwelling amoeba which has been widely used as a model organism to study cellular processes such as signal transduction, chemotaxis, endocytosis and exocytosis. The process of phagocytosis in Dicytostelium is largely comparable to that of neutrophils and macrophages in the mammalian system. Neutrophils and macrophages are cells of the innate immune system and they engulf infectious bacteria through phagocytosis. Dictyostelium cells uptake yeast and bacteria for their nutrition through phagocytosis, which is an actin dependent mechanism and is a target of multi

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40

Komguem, Kamga Christelle. "Cell Toxicity and Uptake of RRR-Alpha-Tocopheryl Polyethylene Glycol 1000 Succinate (TPGS) by Various Cell ines In Vitro." Digital Commons @ East Tennessee State University, 2005. https://dc.etsu.edu/etd/1040.

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This research focused on investigating and comparing the cytotoxicity and cellular uptake of RRR-alpha-tocopheryl polyethylene glycol succinate (TPGS, with that of alpha-tocopheryl succinate (α-TS). Both TPGS and α-TS are water-soluble forms of vitamin E with important clinical applications. Cytotoxicity assays with RAW 264.7 and LNCaP cells incubated overnight with TPGS or α-TS at concentrations ≥ 12.4 μM suggest that α-TS is more cytotoxic than TPGS. Macrophages were found to be more sensitive than LNCaP cells when treated with similar concentrations of α-TS. For both cell lines, most of the

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41

Beveridge, Claire. "Molecular character and role of glutamate uptake in the human hepatocellular carcinoma cell line HepG2." Thesis, University of Bristol, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409007.

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42

Gift, Elizabeth Anne. "A method for measuring electroporative uptake and cell growth using gel microdrops and flow cytometry." Thesis, Massachusetts Institute of Technology, 1993. http://hdl.handle.net/1721.1/115045.

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Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1993.<br>Includes bibliographical references (leaves 96-101).<br>by Elizabeth Anne Gift.<br>M.S.

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43

Clancy, Lauren R. "Platelet Transcriptome Heterogeneity: A Role for RNA Uptake in Vascular Health and Disease." eScholarship@UMMS, 2008. http://escholarship.umassmed.edu/gsbs_diss/922.

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As our understanding of the platelet’s systemic role continues to expand beyond hemostasis and thrombosis, interrogation of the platelet’s ability to affect diverse biological processes is required. Studies of the platelet’s non-traditional roles have focused on developing our understanding of the platelet’s relation to specific disease phenotypes as well as elucidation of platelet characteristics, content, and function. The generic content, traditional function and heterogeneity of platelets have long been accepted; more ambiguous and controversial has been how these factors are interrelated.

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Clancy, Lauren R. "Platelet Transcriptome Heterogeneity: A Role for RNA Uptake in Vascular Health and Disease." eScholarship@UMMS, 2017. https://escholarship.umassmed.edu/gsbs_diss/922.

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As our understanding of the platelet’s systemic role continues to expand beyond hemostasis and thrombosis, interrogation of the platelet’s ability to affect diverse biological processes is required. Studies of the platelet’s non-traditional roles have focused on developing our understanding of the platelet’s relation to specific disease phenotypes as well as elucidation of platelet characteristics, content, and function. The generic content, traditional function and heterogeneity of platelets have long been accepted; more ambiguous and controversial has been how these factors are interrelated.

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45

Oakley, Fiona. "Histidine stimulated trace element uptake into human erythrocytes, HEL cells and HEL total RNA injected Xenopus laevis oocytes." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340362.

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46

Morita, Shin-ya. "Roles of sphingomyelin and ceramide in membrane structure, apolipoprotein binding, and cell uptake of lipid particles." 京都大学 (Kyoto University), 2005. http://hdl.handle.net/2433/145191.

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47

Rockhold, Thomas Hall Jr. "Development of a Knudsen Cell Reactor for Measuring the Uptake of Atmospheric Gases on Particulate Matter." Thesis, Virginia Tech, 2011. http://hdl.handle.net/10919/32194.

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Heterogeneous reactions between mineral dust aerosols and gas phase volatile organic compounds have the potential to impact important atmospheric chemical processes. However, little is known about the uptake and reactivity of volatile organic compounds on particulates found in the environment. A Knudsen cell was designed and constructed for providing precise measurement of reaction probabilities within these systems. The instrument was validated through a series of experiments. After validating the Knudsen cell against several key benchmarks, the instrument was used to measure the uptake coeff

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48

Müller-Greven, Gaëlle Melanie. "Glioma Stem-like Cell Survival is Affected by their Macropinocytic Uptake and Targeted Trafficking of Bevacizumab." Kent State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=kent1520520113612687.

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49

Shir-Mohammadi, Khatereh. "Mechanisms of Acid Secretion and Sodium Uptake in H+-ATPase-rich (HR) Cell of Larval Zebrafish." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39227.

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Freshwater (FW) fish inhabit hypotonic environments that can vary markedly both spatially and temporally with respect to ambient salt levels and pH. Despite the chemical variability of FW, fish maintain ionic homeostasis (ionic regulation) and pH homeostasis (acid-base regulation) by manipulating ion transport mechanisms within ion-transporting cells (ionocytes) localised to the gills of adults and the skin of larvae. Ionocytes are mitochondrion-rich (MR) cells that, depending on subtype, express specific ion transporters that facilitate the movement of salts and acid-base equivalents across t

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50

Okamoto, Takako. "Hepatocyte nuclear factor-1β (HNF-1β) promotes glucose uptake and glycolytic activity in ovarian clear cell carcinoma". Kyoto University, 2014. http://hdl.handle.net/2433/185193.

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Final article is available at "wileyonlinelibrary.com" Takako Okamoto,Masaki Mandai,Noriomi Matsumura,Ken Yamaguchi,Hiroshi Kondoh,Yasuaki Amano,Tsukasa Baba,Junzo Hamanishi,Kaoru Abiko,Kenzo Kosaka,Susan K. Murphy,Seiichi Mori,Ikuo Konishi "Hepatocyte nuclear factor-1β (HNF-1β) promotes glucose uptake and glycolytic activity in ovarian clear cell carcinoma" Molecular Carcinogenesis 54:35–49 (2013)<br>Kyoto University (京都大学)<br>0048<br>新制・論文博士<br>博士(医学)<br>乙第12804号<br>論医博第2076号<br>新制||医||1001(附属図書館)<br>80848<br>京都大学大学院医学研究科医学専攻<br>(主査)教授野田亮, 教授武藤学, 教授稲垣暢也<br>学位規則第4条第2項該当

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