Relevant bibliographies by topics / Cell surfaces

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Cell surfaces'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Cell surfaces"

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Pasternak, C. A. "Cell Surfaces." Interdisciplinary Science Reviews 10, no. 1 (March 1985): 42–55. http://dx.doi.org/10.1179/isr.1985.10.1.42.

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Sentandreu, Rafael, and Teun Boekhout. "Yeast cell surfaces." FEMS Yeast Research 6, no. 7 (November 2006): 947–48. http://dx.doi.org/10.1111/j.1567-1364.2006.00168.x.

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Lamponi, Stefania, Clara Dl Canio, and Rolando Barbucci. "Heterotypic Cell-Cell Interaction on Micropatterned Surfaces." International Journal of Artificial Organs 32, no. 8 (August 2009): 507–16. http://dx.doi.org/10.1177/039139880903200805.

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Purpose The aim of this paper was to study the influence of chemical and topographical signals on cell behavior and to obtain a heterotypic cell-cell interaction on microstructured domains. Methods The polysaccharide hyaluronic acid (Hyal) was photoimmobilized on glass surfaces in order to obtain a pattern with squares and rectangles of different dimensions and chemistry. The microstructured surfaces were characterized by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM). The behavior of Human Coronary Artery Endothelial Cells (HCAEC) and human tumoral dermal fibroblasts (C54) was investigated on these micropatterned surfaces by adhesion studies. Moreover, heterotypic interaction among C54 and HCAEC adherent on patterned surfaces was evaluated by time-lapse video microscopy. Results Surface analysis revealed the presence of a pattern consisting of alternating glass and Hyal microstructures whose dimensions decreased from the center to the edge of the sample. Neither HCAEC nor C54 adhered to the immobilized Hyal but both adapted their shape to the different sizes of the glass squares and rectangles. The number of adherent cells depended on the dimensions of both the glass domains and the nuclei of the cells. Co-cultured C54 on HCAEC patterned surfaces showed a heterotypic cell-cell interaction in the same chemical and topographic domain. Conclusions A heterotypic cell-cell interaction occurred in the same chemical and topographic micro-domains but in narrow areas only. Moreover, the number of cells adhering to the glass domains and cell morphology depended on the dimensions of both adhesive areas and cell nuclei.
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Qi, Jing, Weishuo Li, Xiaoling Xu, Feiyang Jin, Di Liu, Yan Du, Jun Wang, et al. "Cyto-friendly polymerization at cell surfaces modulates cell fate by clustering cell-surface receptors." Chemical Science 11, no. 16 (2020): 4221–25. http://dx.doi.org/10.1039/c9sc06385d.

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Abbina, Srinivas, Erika M. J. Siren, Haisle Moon, and Jayachandran N. Kizhakkedathu. "Surface Engineering for Cell-Based Therapies: Techniques for Manipulating Mammalian Cell Surfaces." ACS Biomaterials Science & Engineering 4, no. 11 (September 11, 2017): 3658–77. http://dx.doi.org/10.1021/acsbiomaterials.7b00514.

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Sedláčková, P., M. Čeřovský, I. Horsáková, and M. Voldřich. "Cell surface characteristic of Asaia bogorensis – spoilage microorganism of bottled water." Czech Journal of Food Sciences 29, No. 4 (August 10, 2011): 457–61. http://dx.doi.org/10.17221/96/2011-cjfs.

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The ability of bacteria to attach to a surface and develop a biofilm has been of considerable interest for many groups in the food industry. Biofilms may serve as a chronic source of microbial contamination and the research into biofilms and cells interactions might help to improve general understanding of the biofilm resistance mechanisms. Multitude of factors, including surface conditioning, surface charge and roughness and hydrophobicity, are thought to be involved in the initial attachment. Hydrophobic interactions have been widely suggested as responsible for much of the adherence of cells to surfaces. Cell-surface hydrophobicity is an important factor in the adherence and subsequent proliferation of microorganisms on solid surfaces and at interfaces. In the present study, we have estimated the cell-surface characteristics of Asaia bogorensis – isolated contamination of flavoured bottled water and compared its ability to colonise surfaces which are typical in the beverage production – stainless steel, glass and plastic materials.
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Dalby, Matthew J. "Nanostructured surfaces: cell engineering and cell biology." Nanomedicine 4, no. 3 (April 2009): 247–48. http://dx.doi.org/10.2217/nnm.09.1.

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Akiyama, Y. "Design of Temperature-Responsive Cell Culture Surfaces for Cell Sheet Engineering." Cyborg and Bionic Systems 2021 (February 3, 2021): 1–15. http://dx.doi.org/10.34133/2021/5738457.

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Temperature-responsive cell culture surfaces, which modulate cell attachment/detachment characteristics with temperature, have been used to fabricate cell sheets. Extensive study on fabrication of cell sheet with the temperature-responsive cell culture surface, manipulation, and transplantation of the cell sheet has established the interdisciplinary field of cell sheet engineering, in which engineering, biological, and medical fields closely collaborate. Such collaboration has pioneered cell sheet engineering, making it a promising and attractive technology in tissue engineering and regenerative medicine. This review introduces concepts of cell sheet engineering, followed by designs for the fabrication of various types of temperature-responsive cell culture surfaces and technologies for cell sheet manipulation. The development of various methods for the fabrication of temperature-responsive cell culture surfaces was also summarized. The availability of cell sheet engineering for the treatment and regeneration of damaged human tissue has also been described, providing examples of the clinical application of cell sheet transplantation in humans.
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Toss, Henrik, Susanna Lönnqvist, David Nilsson, Anurak Sawatdee, Josefin Nissa, Simone Fabiano, Magnus Berggren, Gunnar Kratz, and Daniel T. Simon. "Ferroelectric surfaces for cell release." Synthetic Metals 228 (June 2017): 99–104. http://dx.doi.org/10.1016/j.synthmet.2017.04.013.

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Félez, J. "Plasminogen binding to cell surfaces." Fibrinolysis and Proteolysis 12, no. 4 (July 1998): 183–89. http://dx.doi.org/10.1016/s0268-9499(98)80012-x.

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Dissertations / Theses on the topic "Cell surfaces"

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Kuntanawat, Panwong. "Cell response to anisotropic surfaces." Thesis, University of Glasgow, 2010. http://theses.gla.ac.uk/1885/.

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Cell-substrate interactions are of interest in modern biology. The system of surface bound hydrogels is commonly used as a cell culture surface in the field of cell biomechanics. However, the effect gel geometry (thickness, width and length) has on both the mechanics of the gel and the cells behaviour has usually been ignored. It was discovered that a cell differentially spreads and preferentially accumulates at a certain position with respect to the local variation in thickness along a wedge gel (thickness varied from ~50 to 400 µm). This happened although this range of thickness is supposed to be sufficient to prevent the cells from sensing the underlying rigidity of the supporting glass. The mechanical anisotropy of the gel due to its being bound to the substrate was hypothesised to be the cause of the cell behaviour observed. It was later proven that lateral swelling varies exponentially with thickness. The consequences are the decrease in lateral compression and the lateral dilution of gel network density with increasing gel thickness. Both could cause variations of substrate mechanics. The amount of crosslinker, the geometry of the bound area and type of bathing medium all changed the degree of lateral swelling, and thus are contributing factors influencing the lateral mechanics of the swollen gel. Surface bound square gels (50-2000 μm thick) were found to be stiffer with increasing thickness as measured with an atomic force microscope (AFM). This could be due to a change in osmotic pressure. These indentation based measurements of vertical mechanics might be of little relevance with respect to the cellular response though. This was supported with another set of cell experiments on such samples, where the cell did not respond in accordance with the stiffness as measured by AFM. It was therefore implied that the difference in cell behaviour observed on the substrates of different height might be a result of an interplay between the lateral mechanics and the rate of liquid flow though the gel. The x-, y-aspect ratio was also found to influence cell alignment. Cells tended to align randomly on square (aspect ratio: 1:1), and perpendicular to the direction of the long axis of the gels in high aspect ratio (1:4 – 1:11) gels. This preference could be impaired by inhibition of the interaction between actin and myosin II using blebbistatin treatment. This suggests that actomyosin activity is necessary for such the behaviour. The set of studies stressed the importance of x-, y- and z- macrogeometries of surface bound gels as these factors influence mechanical surface anisotropy. These results could have an implication not only in pure cell biology and cell biomechanics but also in regenerative medicine, physiology, wound healing, embryo development, and oncogenesis, wherever cells are in contact with soft biomaterials or orient themselves with respect to mechanical or other features
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Sinnappan, Snega Marina Graduate School of Biomedical Engineering Faculty of Engineering UNSW. "Cell attachment to peplide modified glass surfaces." Awarded by:University of New South Wales. Graduate School of Biomedical Engineering, 2007. http://handle.unsw.edu.au/1959.4/29559.

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Cell attachment is vital for the integration of biomaterials in the body. Surface modification using cell adhesive peptides, such as Arginine-Glycine-Aspartic (RGD), has showed promise for enhancing cell adhesion. Cell adhesion on glass and polyethylene glycol (PEGylated) surfaces modified with active RGD and Proline- Histidine-Serine-Arginine-Asparagine (PHSRN) peptides as well as inactive RDG and HRPSN control peptides was investigated in serum free conditions using three cell lines; NIH3T3 fibroblasts, MC3T3 pre-osteoblasts and C2C12 pre-myoblasts. Peptide attachment to glass surfaces was confirmed by x-ray photoelectron spectroscopy and contact angle measurements. Cell attachment and spreading was equivalent on all peptide and fibronectin coated glass surfaces and was significantly higher than on unmodified glass after 3 hours. Cell attachment to the peptide modified glass was reduced in the presence of soluble RGD and RDG peptides, indicating that cell attachment to these surfaces may be integrin mediated, but not specific for RGD. Inhibition of protein synthesis with cycloheximide revealed that endogenous protein synthesis did not influence the specificity of cell attachment to the peptide modified glass surfaces in all cell types within a 3 hour period. However, cycloheximide treatment inhibited cell spreading on the peptide modified glass surfaces, suggesting that proteins synthesis was required for spreading. Long term adhesion studies, within a 24 hour period, showed that all cell lines were able to remain attached to the peptide modified glass surfaces, while C2C12 and MC3T3 cells were also able to form focal adhesions during this period. Cell attachment to peptide modified PEGylated surfaces over a 3 hour period showed that NIH3T3 and C2C12 cells experienced significantly higher levels of cell attachment on the RGD modified surface compared to the other peptides. MC3T3 cells attached to all the peptide modified PEGylated surfaces to the same extent, suggesting that cell attachment to peptide modified PEGlyated surfaces, can be cell type dependent. In conclusion all the peptides were able to promote cell adhesion on glass surfaces in the absence of a PEG linker. In the presence of a PEG linker cellular response to the peptide surfaces was both peptide and cell type dependent.
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Hinton, I. E. "The developmental biology of Drosophila cell surfaces." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233464.

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Ambury, Rachael. "Bioactive sugar surfaces for hepatocyte cell culture." Thesis, University of Manchester, 2010. https://www.research.manchester.ac.uk/portal/en/theses/bioactive-sugar-surfaces-for-hepatocyte-cell-culture(122af33a-35b1-47c1-9579-4568fef47543).html.

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The primary objective of this study was to identify, develop and characterise a novel bioactive surface capable of binding hepatocytes and enabling the retention of hepatocyte-specific cell function during in-vitro culture. The materials were designed to exploit a unique characteristic of hepatocyte biology, with β-galactose moieties displayed to allow cellular adhesion via the specific asialoglycoprotein receptors (ASGP-R) found on hepatocytes. Hydrogels were created by modifying a commercially available block co-polymer of polyethylene glycol (PEG) and acrylamide, (PEGA) with galactose moieties contained within lactobionic acid (LA), producing a unique bioactive sugar-based gel. A control sugar, D-glucuronic acid (GA), was used as a non-ASGP-R binding control. Monomers used were mono- and bis-acryloamido PEG (Mw=1900 gmol-1), and dimethylacrylamide. The pendant PEGA amine groups were used as ligands to bind to the sugars. The resultant gels were characterised using Fourier Transform Infrared Spectroscopy (FT-IR), protein adsorption, Fmoc-Phe and dansyl chloride labelling. The biocompatibility of the gel surfaces was evaluated using a hepatocyte cell line and the degree of attachment, proliferation, and morphology was characterised using light microscopy, live/dead assays, DNA assays, immunochemical staining, flow cytometry and reverse-transcription polymerase chain reaction (RT-PCR).FT-IR analysis of LA revealed a distinctive band at approximately 1740cm-1 corresponding to carbonyl stretching (C=O) of carboxylic acid. This unique peak disappeared as the galactose moieties within the LA were incorporated into the PEGA gel. A similar trend was also observed with the control GA sugar within the PEGA gel, confirming that the sugars had been integrated into the material. Protein adsorption assays confirmed the non-fouling nature of PEGA. Cell culture experiments showed that hepatocytes attached preferentially to the sugar surfaces, with few cells seen on the PEGA surfaces. It was observed that cells on the PEGA with LA surface were more metabolically active, than the controls and proliferated to a monolayer by day 7 in culture. Immunocytochemical staining of the cells for actin, vinculin and phosphorylated focal adhesion kinase illustrated differences in cell morphology between cells grown on different surfaces. It was determined that the sugar PEGA surfaces maintained some characteristics of hepatocyte functionality e.g. urea synthesis over the course of 7 days. To improve the reproducibility of the surfaces generated, a preliminary investigation of two-dimensional PEG monolayer surfaces as a well defined platform for surface reactions was conducted. These were chemically functionalised in a stepwise manner with the sugars. The number of coupling steps and the choice of solvent were shown to affect the efficiency of the reaction. Further more, the need for careful sample preparation was highlighted as contamination could potentially inhibit the interpretation of the surface chemistry.The overall conclusion of this work is that saccharides within non-fouling surfaces composed of thin layers of PEG-acrylamide hydrogels are able to support hepatocyte attachment and the retention of cell type specific functions in culture. However, this preliminary work has shown that much further research is necessary to elucidate the role that the surface chemistry plays in the attachment of hepatocytes.
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Barch, Mariya. "Molecular fluorescent reporters for force and smart surfaces for sensing cell-surface interaction." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/55089.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2009.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 123-130).
Molecular sensors are powerful because they make it possible to adapt the measurement to the sample instead of a sample to an instrument. Many reporter are available for measuring the chemical properties of a sample, but no purpose-built molecular sensors exist to report a sample's mechanical properties. To address recent interest in the mechanical coordinate of molecular interactions, we developed a prototype molecular sensor, calibrated its force-fluorescence relationship, and adapted the sensor to a cell adhesion assay. This thesis focuses on the considerations for combining force measurement with the environmental and distance sensitivity offered by fluorescence to measure cell-surface adhesion. We showed that DNA can be used as a scaffold to build a sensor molecule, that fluorescence can be used as a reporter of a threshold force, and that introducing cells to the sensor molecules changes the fluorescence properties. Because Cy3 experiences an enhanced intensity sensitivity when conjugated to DNA, the reporter's FRET signal was occluded and we instead activated the sensor complex as a novel, all-fluorescent means of reporting cell-surface proximity. This method for reporting cell-surface separation is significant because it simplifies measurements in thicker and more complex materials interesting to cell-substrate interaction studies.
by Mariya Barch.
Ph.D.
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Lord, Megan Susan Graduate School of Biomedical Engineering Faculty of Engineering UNSW. "Biomolecular and cellular interactions with surfaces." Awarded by:University of New South Wales. Graduate School of Biomedical Engineering, 2006. http://handle.unsw.edu.au/1959.4/24213.

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The modulation of biological interactions with artificial surfaces is a vital aspect of biomaterials research. Protein adsorption is established as an early biological response to implanted materials that influences biocompatibility, hence an understanding of how to direct specific protein and cellular responses is critical for the development of future biomaterials. The effects of protein adsorption and subsequent cellular interactions on a variety of surfaces are investigated. Acrylic-based hydrogels are used as a model system in which to investigate both tear and serum protein adsorption from simple and complex solutions. The effect of surface topography, created by colloidal silica, on serum protein adsorption and conformation as well as cell adhesion is also investigated. Tantalum (Ta) and oxidised polystyrene (PSox) are investigated for their ability to support cell adhesion when precoated with various serum proteins. Protein interactions are examined using a combination of quartz crystal microbalance with dissipation (QCM-D), surface plasmon resonance (SPR), dual polarisation interferometry (DPI) and enzyme-linked immunosorbent assay (ELISA) while cellular interactions are analysed using QCM-D, microscopy and adhesion assays. The QCM-D technique was evaluated for its ability to provide new insight into cell-surface interactions. Most tear and serum proteins were found to adsorb onto the acrylic hydrogels, however, lysozyme was found to absorb into the hydrogel matrix and decrease the hydration, which may lead to an adverse biological response. Fibronectin adsorbed onto nanotextured colloidal silica surfaces was found to be conformationally changed compared to flat controls which is likely to correlate with the reduced endothelial cell adhesion observed on these textured surfaces. Ta and PSox precoated with either serum or fibronectin were shown to support cell adhesion and spreading, while surfaces precoated with albumin were not. QCM-D responses varied between underlying surfaces, protein precoating, ECM deposition, cytoskeletal activity and length of exposure indicating that alterations in cell-material responses are reflected in QCM-D measurements. QCM-D parameters were found to correlate with adhered cell numbers, cell contact area and cytoskeletal activity. The results highlight that characterisation of interfacial interactions with a wide range of analytical techniques is necessary to gain insight into cell-protein-material interactions which can then be utilised in the development of new generations of biomaterials with improved properties designed for specific applications.
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Tong, Yen Wah. "Defining fluoropolymer surfaces for enhanced nerve cell interaction." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0026/NQ49834.pdf.

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Manning, Paul Alexander. "Bacterial cell surfaces and pathogensis : publications 1975-1998 /." Title page, contents and summary only, 1998. http://web4.library.adelaide.edu.au/theses/09SD/09sdm284.pdf.

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Reyes-Cuellar, Julia Constanza. "REACTIONS AND PROCESSES AT CELL-MIMICKING MEMBRANE SURFACES." OpenSIUC, 2017. https://opensiuc.lib.siu.edu/dissertations/1402.

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As a self-assembled mimetic structure of biological membranes, polydiacetylene liposomes have been studied for the development of platforms for various applications including nano-containers, nano-transporters, and nano-delivery systems for biological-, life- and materials-science applications. Liposomes incorporating amphiphilic polymer poly(10, 12 pentacosadiynoic acid) (PDA) was used as a building block for investigations mimicking cellular reaction and processes at the membrane cell. Changes in local membrane micro-organization and packing as a result of biomolecular and bioparticle reactions and processes at the liposomal membrane were investigated through the use of colorimetric and emission responses of PDA liposomes in solution phase. My dissertation comprises of six chapters. I provide brief overview of each chapter in the following paragraphs: Chapter 1: Introduction. In this chapter, an introduction is given on structure and function of lipid bilayer and multilayer of liposomes from a perspective of shared features with biological membranes. Amphiphilic molecules along with natural lipids at (or higher) critical micelle concentration self-assemble in aqueous medium, thereby, forming a lipid bilayer or multilayer to reduce the free energy of the system. When one of the components of the lipid bilayer is a polymerizable monomer, micelles/liposomes with enhanced mechanical and chemical stability are achieved. The lipid bilayer of liposomes is a boundary that includes at least three different regions: inside aqueous cavity, hydrophobic membrane zone, and membrane-aqueous interfaces. The membrane surface is available for further functionalization. In general, all three regions of the liposomes are utilized for both fundamental and applied studies. For example, the PDA liposomes have been employed for biosensing, drug/protein/nucleic acid transport and delivery and target release, and various probing cellular-like reactions and processes at the membranes. Here, in this chapter, literature on PDA was reviewed for a time period of 2008-2015. Furthermore, emphasis was given to application of PDA liposomes as (bio) sensing elements utilizing colorimetric, fluorescence, and FRET mechanisms. Chapter 2. Polydiacetylene (PDA) liposomes have been accepted as attractive colorimetric bionanosensors. The molecular recognition elements, either embedded within the liposomal membrane or covalent bound at the membrane surface, are available for interaction with biological and chemical analytes. Usually, PDA liposomes perform transduction activity through perturbation of the conjugated polymer backbone, which provides a colorimetric change in solution or solid-state phase. Here, we report that trapping self-quenched fluorescent specie within inner cavity of the liposomes is a simple and effective analytical tool for evaluating biomolecular binding events at the membrane surface. The release of fluorophores in response to the membrane binding event led to amplified emission signal which was utilized for probing reactions at the membrane surface that mimics reactions occurring at the cellular membrane surface. Specifically, a covalent binding on enzyme-substrate reaction resulted in a change of membrane fluidity, thereby releasing inner fluorophore content of the PDA liposomes. Fluorescent markers were loaded at or higher self-quenched concentration in the cavity of the liposome. Amplification of the fluorescence intensity was positively correlated with the concentration of protein added in the solution. The bilayer fluidity alteration also appears to depend on the molecular weight of the protein bound at the membrane. Overall, binding of protein with membrane promoted changes in the local PDA membrane organization and packing that enhanced the membrane permeability. The encapsulated content therefore leaked through “transient pores” formed in the membrane yielding substantial emission amplification. Chapter 3. Inspired by stability of the PDA liposomes, surface functionalization with a variety of molecules and loading within bilayer and inner cavity of the liposomes, we utilized liposomes as biocatalytical nanoreactors. Removable template molecules were embedded in the lipid bilayer and active protein encapsulated in the internal cavity was used for studying the transport properties of liposomes through substrate-enzyme reactions. Detergent Triton X-100 was used to remove a small portion of lipid and template molecules embedded in the membrane. The removal of lipid/template molecules not only affected the membrane fluidity but also provided transient pores in the membrane, allowing transport of substrate for enzymatic oxidation of glucose and 2-deoxy-glucose. Three important biological-relevant properties of cellular membrane: transport, bioavailability, and bio-reactivity of enzyme and substrate were studied. We found that enzyme molecules retained their reactivity when encapsulated within the aqueous inner cavity of the PDA liposomes, and that their activity was comparable to that in the bulk solution. Chapter 4. This chapter introduces studies on (at least partially) answering important questions how and if anchored enzyme activity at the liposome surface is affected through limited diffusion and spatial constraints. A further crucial question was investigated what effect of protein binding at the surface of the liposomes to enzymatic activity was. These relevant questions were important for increasing our fundamental knowledge related to reactions, interactions, and transport processes in biological cellular systems. A functionalized liposome system containing enzyme (Trypsin) covalently attached at the PDA liposome surface was synthesized. Using PDA liposomes as an immobilization scaffold, we evaluated and compared the cleavage behaviors of Trypsin in either immobilized at the membrane surface or in the free form. The covalent binding interaction and tryptic cleavage at the membrane-water interface was monitored by UV-vis and fluorescent spectroscopy, fluorescent anisotropy and spectro-micro-imaging. Trypsin binding at the membrane appeared to be significantly affected the enzymatic activity of the bound enzyme as seen from colorimetric response of the PDA liposomes. Chapter 5. Hierarchical structures support structures with new functionalities, therefore, advances in fabrication and characterization of biomimetic systems based on biological building blocks may present substantial potential rewards in material science. We take advantage of non-covalent forces known in biology for creating spatial organization by assembly tobacco mosaic virus-liposome polymeric hierarchical systems through biotin-streptavidin linkages. The advantage of using the biological thin rods such as TMV is that it can span the whole liposomal membrane allowing us to create microscopic hinge structures that connected liposomes. Our findings through electron and fluorescence microscopy confirmed that SA-TMV motif was able to stay inserted within the lipid bilayer of liposomes which yielded hierarchical structures after binding with Bt-liposomes. These hierarchical structures may find potential applications in targeted load (drug/protein/DNA) delivery, investigations involving virus-cell interactions, and sensing of virus particles. Chapter 6. Conclusions and Future work The present work in this dissertation utilized exploitation of biological self-assembly of small lipid molecules and larger biological-like motifs for enhancing our understanding of reactions and processes occurring at the cellular membrane surface. Overall the following four major studies were accomplished; 1. Sensing through amplified delivery, 2. Triggering an encapsulated bioreactor system at nanometric size, 3. Holding active biological elements when liposomes perform an attachment matrix, 4. Formation of hierarchical structures promoted by self-assembling of biological motifs with mimickers of cell membrane From our findings by mimicking the lipid bilayer of cell structures through liposomal membrane future work holds different ways to contribute in enhancing fundamental understanding of biological behavior. Active transport is an important function of all natural cells, playing important roles in intercellular communication. Liposomes composed of natural and polymerizable lipids may allow investigation involving exocytosis, formation of filopodia, vesicle fusion, budding and reproduction of neural synapses. Our liposome system may also mediate a broader range of highly selective and sensitive detection and sensing of cellular reactions and processes in physiological condition. I hope that this work in collaboration with multiple PIs will contribute to the fields at the interface of biology and material science.
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Lammert, Eckhard, Vincent Laudet, Michael Schubert, Kathrin Regener, Boris Strilic, and Tomas Kucera. "Ancestral vascular lumen formation via basal cell surfaces." PLOS one, 2009. https://tud.qucosa.de/id/qucosa%3A28997.

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The cardiovascular system of bilaterians developed from a common ancestor. However, no endothelial cells exist in invertebrates demonstrating that primitive cardiovascular tubes do not require this vertebrate-specific cell type in order to form. This raises the question of how cardiovascular tubes form in invertebrates? Here we discovered that in the invertebrate cephalochordate amphioxus, the basement membranes of endoderm and mesoderm line the lumen of the major vessels, namely aorta and heart. During amphioxus development a laminin-containing extracellular matrix (ECM) was found to fill the space between the basal cell surfaces of endoderm and mesoderm along their anterior-posterior (A-P) axes. Blood cells appear in this ECM-filled tubular space, coincident with the development of a vascular lumen. To get insight into the underlying cellular mechanism, we induced vessels in vitro with a cell polarity similar to the vessels of amphioxus. We show that basal cell surfaces can form a vascular lumen filled with ECM, and that phagocytotic blood cells can clear this luminal ECM to generate a patent vascular lumen. Therefore, our experiments suggest a mechanism of blood vessel formation via basal cell surfaces in amphioxus and possibly in other invertebrates that do not have any endothelial cells. In addition, a comparison between amphioxus and mouse shows that endothelial cells physically separate the basement membranes from the vascular lumen, suggesting that endothelial cells create cardiovascular tubes with a cell polarity of epithelial tubes in vertebrates and mammals.
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Books on the topic "Cell surfaces"

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Delcour, Anne H., ed. Bacterial Cell Surfaces. Totowa, NJ: Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-245-2.

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Wiessner, Wolfgang, David G. Robinson, and Richard C. Starr, eds. Cell Walls and Surfaces, Reproduction, Photosynthesis. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-48652-4.

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Tiwari, Ashutosh, Bora Garipcan, and Lokman Uzun, eds. Advanced Surfaces for Stem Cell Research. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781119242642.

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1933-, Wiessner Wolfgang, Robinson David G, and Akademie der Wissenschaften in Göttingen., eds. Cell walls and surfaces, reproduction, photosynthesis. Berlin: Springer Verlag, 1990.

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Nikolaev, Igor. Foliations on Surfaces. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001.

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Rawlingson, Heidi Joan. Gamate cell surfaces and fertilisation in Fucus. Birmingham: University of Birmingham, 1995.

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Futer, David. Guts of Surfaces and the Colored Jones Polynomial. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013.

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England), Institute of Basic Medical Sciences Symposium on Interaction of Cells with Natural and Foreign Surfaces (1984 Royal College of Surgeons of. Interaction of cells with natural and foreign surfaces. New York: Plenum Press, 1986.

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Gallier, Jean. A Guide to the Classification Theorem for Compact Surfaces. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013.

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Schneck, Emanuel. Generic and Specific Roles of Saccharides at Cell and Bacteria Surfaces. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-15450-8.

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Book chapters on the topic "Cell surfaces"

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Wen, Jessica H., Hermes Taylor-Weiner, Alexander Fuhrmann, and Adam J. Engler. "Cell Mechanics on Surfaces." In Biomaterials Surface Science, 511–37. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527649600.ch18.

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Wolfschmidt, Holger, Odysseas Paschos, and Ulrich Stimming. "Hydrogen Reactions on Nanostructured Surfaces." In Fuel Cell Science, 1–70. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470630693.ch1.

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Harmand, M. F. "Human Cell Culture and Characterization of Cell/Biomaterial Interface." In Biologically Modified Polymeric Biomaterial Surfaces, 145–50. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-1872-9_19.

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El-Said, Waleed Ahmed, Tae-Hyung Kim, Ki-Bum Lee, and Jeong-Woo Choi. "Nanopatterned Surfaces for Stem-Cell Engineering." In Stem-Cell Nanoengineering, 97–122. Hoboken, NJ: John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781118540640.ch7.

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Pulsipher, Abigail, and Muhammad N. Yousaf. "Self-Assembled Monolayers as Dynamic Model Substrates for Cell Biology." In Bioactive Surfaces, 103–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/12_2010_87.

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Fisher, Derek, Cristina Delgado, John Morrison, Gerald Yeung, and Colin Tilcock. "Pegylation of Membrane Surfaces." In Cell and Model Membrane Interactions, 47–62. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3854-7_4.

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Dabo, Ismaila, Yanli Li, Nicéphore Bonnet, and Nicola Marzari. "Ab Initio Electrochemical Properties of Electrode Surfaces." In Fuel Cell Science, 415–31. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470630693.ch13.

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Crawford, N. "Electrokinetic Aspects of Cell Surfaces." In Interaction of Cells with Natural and Foreign Surfaces, 11–20. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2229-0_2.

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Gingell, David. "Cell contact with solid surfaces." In Springer Series in Biophysics, 263–85. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74471-6_14.

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Wicken, Anthony J. "Bacterial Cell Walls and Surfaces." In Bacterial Adhesion, 45–70. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4615-6514-7_2.

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Conference papers on the topic "Cell surfaces"

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Matsusaki, Michiya, and Mitsuru Akashi. "3D-cell assembly by control of cell surfaces." In 2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS). IEEE, 2015. http://dx.doi.org/10.1109/mhs.2015.7438309.

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Dalchiele, E. A., J. M. Rosolen, and F. Decker. "Photoelectrochemical characterization of AxC60(A=Li,K) thin films in a solid state cell." In The 8th Latin American congress on surface science: Surfaces , vacuum, and their applications. AIP, 1996. http://dx.doi.org/10.1063/1.51188.

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Sartini de Oliveira, Lidiane, Cleudmar Amaral de Araújo, Fernando Lourenço de Souza, Gustavo Mendonça, Daniela B. S. Mendonça, and Sonia A. Goulart Oliveira. "Influence of Surface Energy in the Osteogenesis Process of Treated Titanium Surfaces." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-52476.

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In the 1960’s, Brånemark and colleagues developed a dental implant system using a direct attachment to bone structure without generating soft tissue. This phenomenon called osseointegration involves biomechanical behavior of materials. In several studies it has been verified that the surface treatment on titanium implant has been the main factor for the osteogenesis process and, consequently, osseointegration [1, 2, 3]. Treated titanium surfaces have better conditions for cell adhesion that can lead to load application in the shortest time. The aim of this study was to evaluate the surface energy and the cell osteogenesis on titanium discs under different conditions of blasting and acid attack. Osteoblastic cells Hfob 1.19 were used to measure cell culture parameters like cell viability and cell proliferation, alkaline phosphatase activity and mineralized nodule formation. Osteogenesis cell was defined through a mathematical model proposed by a similitude in engineering with osteogenic parameters analyzed in culture cells. Fowkes Theory was used to calculate the surface energy by measuring contact angles between liquid sensors (Deionized Water, Chloroform) on different titanium surfaces. Significant difference (P < 0,01) was observed for surface energies ranging between 26,76 a 33,81 mJ/m^2 using ANOVA and Bonferroni test. It was noted that the highest surface energies are related with osteogenesis levels.
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Calero, J. M., and J. C. Granada. "Collective excitations and coupling between CuO2 layers in superconducting systems with two layers per cell." In The 8th Latin American congress on surface science: Surfaces , vacuum, and their applications. AIP, 1996. http://dx.doi.org/10.1063/1.51104.

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Wang, Hengyu, Jeong-Hwan Kim, Min Zou, Steve Tung, and Jin-Woo Kim. "The Effect of Surface Nano/Micro-Texturing on Escherichia Coli Cell Adhesion." In 2008 Second International Conference on Integration and Commercialization of Micro and Nanosystems. ASMEDC, 2008. http://dx.doi.org/10.1115/micronano2008-70146.

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Control of cell-to-surface adhesion has significant impacts on various biological and biomedical applications. In this study, the adhesion of Escherichia coli (E. coli) cells on nano/micro-textured surfaces produced by a unique surface texturing technique, aluminum-induced crystallization (AIC) of amorphous silicon (a-Si), was studied in order to control E. coli cell adhesion on glass substrates in an E. coli-based whole-cell chemical sensor. It was found that textured surfaces significantly enhanced cell-to-surface adhesion. Among the textured surfaces, nano/micro-textured surfaces showed advantage over micro-textured surfaces on the cell-to-surface adhesion. Study of the cell-to-surface adhesion mechanism suggests that the cell adhesion efficiency was controlled by the particle density of the textured surfaces.
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Tang, Zhonglan, Yoshikatsu Akiyama, and Teruo Okano. "Temperature-responsive Cell Culture Surfaces for Cell Sheet Tissue Engineering." In In Commemoration of the 1st Asian Biomaterials Congress. WORLD SCIENTIFIC, 2008. http://dx.doi.org/10.1142/9789812835758_0004.

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Mwenifumbo, Steven, Mingwei Li, and Wole Soboyejo. "Cell/surface interactions on laser-micro-textured titanium-coated silicon surfaces." In Lasers and Applications in Science and Engineering, edited by Peter R. Herman, Jim Fieret, Alberto Pique, Tatsuo Okada, Friedrich G. Bachmann, Willem Hoving, Kunihiko Washio, et al. SPIE, 2004. http://dx.doi.org/10.1117/12.531643.

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Chung-Yao Yang, Chun-Yen Sung, and J. Andrew Yeh. "Nanotextured chitosan surfaces for studying cell behaviors." In 2013 8th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). IEEE, 2013. http://dx.doi.org/10.1109/nems.2013.6559710.

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Okano, T. "Intelligent surfaces for cell sheet tissue engineering." In 2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII). IEEE, 2013. http://dx.doi.org/10.1109/transducers.2013.6626687.

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Durmaz, Yasin C., Alexandra Goetz, and Fritz Keilmann. "Infrared Nanoscopy of Alive Biological Cell Surfaces." In 2019 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz). IEEE, 2019. http://dx.doi.org/10.1109/irmmw-thz.2019.8873819.

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Reports on the topic "Cell surfaces"

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Bertozzi, Carolyn R. Metabolic Engineering of Reactive Cell Surfaces for Controlled Cell Adhesion. Fort Belvoir, VA: Defense Technical Information Center, September 2001. http://dx.doi.org/10.21236/ada421093.

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Allara, David L. Characterization of the Molecular Basis of Cell Recognition at Surfaces. Fort Belvoir, VA: Defense Technical Information Center, December 1998. http://dx.doi.org/10.21236/ada384249.

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McElfresh, M., J. Belak, R. Rudd, and R. Balhorn. LDRD Final Report 01-ERI-001 Probing the Properties of Cells and Cell Surfaces with the Atomic Force Microscope. Office of Scientific and Technical Information (OSTI), February 2004. http://dx.doi.org/10.2172/15013864.

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Fridman, Rafael A. Cell Surface Regulation of Matrix Metalloproteinases in Breast Cancer Cells. Fort Belvoir, VA: Defense Technical Information Center, August 2001. http://dx.doi.org/10.21236/ada396698.

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Pizzo, Salvatore, and Robin E. Bachelder. Targeting Prostate Cancer Stemlike Cells through Cell Surface-Expressed GRP78. Fort Belvoir, VA: Defense Technical Information Center, October 2014. http://dx.doi.org/10.21236/ada613546.

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Fridman, Rafael A. Cell Surface Regulation of Matrix Metalloproteinases in Breast Cancer Cells. Fort Belvoir, VA: Defense Technical Information Center, August 2003. http://dx.doi.org/10.21236/ada423044.

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Fridman, Rafael A. Cell Surface Regulation of Matrix Metalloproteinases in Breast Cancer Cells. Fort Belvoir, VA: Defense Technical Information Center, August 2000. http://dx.doi.org/10.21236/ada395379.

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Pizzo, Salvatore. Targeting Prostate Cancer Stem-Like Cells Through Cell Surface-Expressed GRP78. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada601082.

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Hollingsworth, Rawle. Cell surface glycoconjugates of Rhizobium and symbiosis. Office of Scientific and Technical Information (OSTI), May 2001. http://dx.doi.org/10.2172/794175.

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Al-Attar, Ali. Cell Surface Molecules Driving Breast Cancer/Endothelial Interactions. Fort Belvoir, VA: Defense Technical Information Center, July 2001. http://dx.doi.org/10.21236/ada396252.

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