Academic literature on the topic 'CDC'

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Journal articles on the topic "CDC"

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Idigbe, Emmanuel Oni, Rosemary A. Audu, Edna O. Iroha, Adebola O. Akinsulie, Edamisan Olusoji Temiye, Veronica C. Ezeaka, Ifedayo M. O. Adetifa, Adesola Z. Musa, Joseph Onyewuche, and Sylvester U. Ikondu. "T-Lymphocyte Subsets in Apparently Healthy Nigerian Children." International Journal of Pediatrics 2010 (2010): 1–7. http://dx.doi.org/10.1155/2010/474380.

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Population studies showed that there are differences in T-lymphocytes subpopulation of normal children in different regions, and reference values in an area might be different from another. This study compared the values in our population with CDC and WHO reference values. Blood samples from 279 healthy, HIV-negative children<12 years of age were analysed for complete blood count, CD3+, CD4+, CD8+ counts and percentages. Except for CD8%, mean values for all parameters measured significantly decreased with age. CD4+ counts were higher in females than males,P<.05. Using the WHO criteria, 15.9% of subjects had low total lymphocyte count and 20.6% had low CD4 count. Children<3 years had median CD4% lower than WHO normal values. Our median CD4+ counts correlated with CDC values. Values used by WHO in infants are higher than ours. We suggest that our children be assessed using CDC reference values which correlate with ours.
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Chatila, T. A., and R. S. Geha. "Phosphorylation of T cell membrane proteins by activators of protein kinase C." Journal of Immunology 140, no. 12 (June 15, 1988): 4308–14. http://dx.doi.org/10.4049/jimmunol.140.12.4308.

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Abstract Activation of the enzyme protein kinase C (PKC) plays an important role in T cell activation. We investigated the phosphorylation of CD2, CD3, CD4, CD5, CD7, CD8, CD28 (Tp44), CD43 (sialophorin, gp115), and LFA-1 after incubation of human PBMC with the (PKC) activator PMA. These proteins were chosen for their role in transmembrane signal transduction (CD2, CD3, CD5, CD28, CD43), cell-cell interaction and adhesion (CD2, CD4, CD8, and LFA-1), or involvement in immunodeficiency states (CD43, CD7). CD5, CD7, CD43, and the alpha-chain of LFA-1 were found to be constitutively phosphorylated. PMA induced rapid hyperphosphorylation of CD5, CD7, and CD43, but not of the LFA-1 alpha-chain, and induced the phosphorylation of CD3, CD4, CD8 and of the LFA-1 beta-chain. PMA did not cause the phosphorylation of CD2 and CD28. PMA-induced phosphorylation was partially inhibited by the PKC inhibitor 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine dihydrochloride. Finally, the T cell activator Con A, which binds to the CD3/TCR complex was shown to induce a profile of protein phosphorylation similar to that observed with PMA. We conclude that PKC-mediated phosphorylation of T cell Ag may represent an important regulatory mechanism that governs the process of T cell activation.
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Raimondi, SC, FG Behm, PK Roberson, CH Pui, GK Rivera, SB Murphy, and DL Williams. "Cytogenetics of childhood T-cell leukemia." Blood 72, no. 5 (November 1, 1988): 1560–66. http://dx.doi.org/10.1182/blood.v72.5.1560.1560.

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Abstract The karyotypes of 57 cases of childhood T-cell acute lymphoblastic leukemia (ALL) were analyzed to establish the cytogenetic profile in this disease. Three questions were of particular interest. Do the chromosomal changes in T-cell ALL preferentially affect bands where genes encoding the T-cell receptor for antigen (TCR) have been mapped? Do alterations involving the TCR gene regions appear with any notable frequency in B-progenitor ALL? Do chromosomal abnormalities in this disease relate to stage of T-cell ontogeny? A relatively high proportion of cases (65%) had a pseudodiploid karyotype at presentation, the majority (58%) characterized by a translocation. The overall frequency of translocations was 44%, comparable to that among all banded cases of ALL seen in our laboratory. Hypodiploidy and hyperdiploidy were exceedingly rare (only four of 57 cases); 16 cases (28%) had apparently normal karyotypes. In half the cases with a translocation (14 of 24), the breakpoints were in regions to which the alpha and beta chain TCR genes have been mapped. Chromosomal breakpoints that were consistently observed in the vicinity of TCR gene loci were 7q32-q36 (TCR beta chain; n = 8), 14q11-q13 (TCR alpha chain; n = 6); other frequent breakpoints were 9p13-pter (n = 8) and 6q15-qter (n = 9). Chromosomal alterations occurred near TCR gene loci significantly more often in T-cell cases than in a comparison group of 335 patients with B-cell precursor ALL (26% v 1.5%, P = .0001). Stage I thymocyte development (CD7+, CD2+, CD5+, CD1-, CD3-, CD4-, CD8-) was noted in 23 cases, stage II (CD7+, CD2+, CD5+, CD1+, CD3-, CD4 +/-, CD8 +/-) in 25 cases, and stage III (CD9+, CD2+, CD1-, CD5+, CD3+, and either CD4+ or CD8+) in nine cases. The only statistically significant associations between cytogenetic findings and T-cell ontogeny were a higher frequency of normal karyotypes in cases with stage I thymocytes, and of pseudodiploidy in stage II cases. There was no apparent relationship between particular translocations and level of thymocyte maturation. Our findings indicate that most children with T-cell ALL have pseudodiploid karyotypes, although a surprisingly high percentage lack demonstrable abnormal clones. Specific chromosomal changes do not appear to be related to discrete stages of T-cell ontogeny as defined in this study, but they occur preferentially in bands containing TCR genes.
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Raimondi, SC, FG Behm, PK Roberson, CH Pui, GK Rivera, SB Murphy, and DL Williams. "Cytogenetics of childhood T-cell leukemia." Blood 72, no. 5 (November 1, 1988): 1560–66. http://dx.doi.org/10.1182/blood.v72.5.1560.bloodjournal7251560.

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The karyotypes of 57 cases of childhood T-cell acute lymphoblastic leukemia (ALL) were analyzed to establish the cytogenetic profile in this disease. Three questions were of particular interest. Do the chromosomal changes in T-cell ALL preferentially affect bands where genes encoding the T-cell receptor for antigen (TCR) have been mapped? Do alterations involving the TCR gene regions appear with any notable frequency in B-progenitor ALL? Do chromosomal abnormalities in this disease relate to stage of T-cell ontogeny? A relatively high proportion of cases (65%) had a pseudodiploid karyotype at presentation, the majority (58%) characterized by a translocation. The overall frequency of translocations was 44%, comparable to that among all banded cases of ALL seen in our laboratory. Hypodiploidy and hyperdiploidy were exceedingly rare (only four of 57 cases); 16 cases (28%) had apparently normal karyotypes. In half the cases with a translocation (14 of 24), the breakpoints were in regions to which the alpha and beta chain TCR genes have been mapped. Chromosomal breakpoints that were consistently observed in the vicinity of TCR gene loci were 7q32-q36 (TCR beta chain; n = 8), 14q11-q13 (TCR alpha chain; n = 6); other frequent breakpoints were 9p13-pter (n = 8) and 6q15-qter (n = 9). Chromosomal alterations occurred near TCR gene loci significantly more often in T-cell cases than in a comparison group of 335 patients with B-cell precursor ALL (26% v 1.5%, P = .0001). Stage I thymocyte development (CD7+, CD2+, CD5+, CD1-, CD3-, CD4-, CD8-) was noted in 23 cases, stage II (CD7+, CD2+, CD5+, CD1+, CD3-, CD4 +/-, CD8 +/-) in 25 cases, and stage III (CD9+, CD2+, CD1-, CD5+, CD3+, and either CD4+ or CD8+) in nine cases. The only statistically significant associations between cytogenetic findings and T-cell ontogeny were a higher frequency of normal karyotypes in cases with stage I thymocytes, and of pseudodiploidy in stage II cases. There was no apparent relationship between particular translocations and level of thymocyte maturation. Our findings indicate that most children with T-cell ALL have pseudodiploid karyotypes, although a surprisingly high percentage lack demonstrable abnormal clones. Specific chromosomal changes do not appear to be related to discrete stages of T-cell ontogeny as defined in this study, but they occur preferentially in bands containing TCR genes.
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Amalia, Fatya Alty, Arie Indra Gunawan, and Nono Wibisono. "Citra Destinasi Wisata Halal di Jepang: Wisatawan Dan Non-Wisatawan Muslim Dari Indonesia." Jurnal Bisnis dan Kewirausahaan 17, no. 1 (April 6, 2021): 1–10. http://dx.doi.org/10.31940/jbk.v17i1.2473.

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Wisata halal merupakan salah satu sektor bisnis halal yang masih berkembang karena banyaknya potensi wisatawan yang masih dapat dimanfaatkan lebih lanjut. Sebagai seorang wisatawan yang memiliki beberapa pilihan destinasi wisata halal, proses pengambilan keputusannya mengenai destinasi yang dipilih dapat sangat dipengaruhi oleh citra destinasi pada atribut wisata halal di destinasi tersebut. Penelitian ini bertujuan untuk mengkaji citra destinasi wisata halal di Jepang dari wisatawan dan non-wisatawan muslim Indonesia. Untuk pendataan dilakukan survey online (Mei-Juni 2020) terhadap umat Islam Indonesia dan menghasilkan 263 respon valid. Berdasarkan 12 atribut, 263 tanggapan tersebut dianalisis menggunakan uji Mann-Whitney U dan dilanjutkan untuk menguji ukuran efeknya. Hasil penelitian menunjukkan bahwa terdapat 3 dari 12 atribut (CD1, CD4, dan CD10) yang tidak berbeda nyata antara kelompok wisatawan dan non-wisatawan. Sedangkan atribut sisanya berbeda nyata antara kedua kelompok. Secara spesifik, gambaran CD3, CD5, dan CD12 pada wisatawan lebih kuat dibandingkan non-wisatawan. Di sisi lain, citra non-pengunjung dalam bentuk CD2, CD6, CD7, CD8, CD9, dan CD11 lebih kuat dari pada wisatawan. Berdasarkan temuan tersebut, Jepang sebaiknya menyesuaikan strategi promosinya berdasarkan sasarannya, baik wisatawan yang sudah memiliki pengalaman aktual maupun non-wisatawan yang hanya mengandalkan citra sekundernya.
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Park, Sang Chul, Tae-Gyun Kim, Hyung-Ju Cho, Chang-Hoon Kim, and Joo-Heon Yoon. "Reduced BDCA3+ dendritic cells in nasal mucosa induce severe inflammation in patients with allergic rhinitis and chronic rhinosinusitis." Journal of Immunology 204, no. 1_Supplement (May 1, 2020): 147.12. http://dx.doi.org/10.4049/jimmunol.204.supp.147.12.

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Abstract Dendritic cells (DCs) are specialized antigen-presenting cells that play a crucial role in T helper (Th) cell differentiation. DCs of human airway comprise conventional DCs (cDCs) and plasmacytoid DCs (pDCs), of which the cDCs lineage consists of cDC type 1 (cDC1) and cDC type 2 (cDC2). These DCs subsets differ in ontogeny and functional properties in immune response. Thus, we aimed to evaluate the expression of different dendritic cell subsets in nasal mucosa of patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS). Nasal polyp tissues or ethmoid mucosa from patients undergoing endoscopic sinus surgery or septoplasty were collected. The expression of DCs was investigated by flow cytometry via surface markers including BDCA-1 (CD1c) for cDC1, BDCA-3 (CD141) for cDC2, and BDCA-2 (CD303) for pDC. In subjects with AR, BDCA-3+cDC levels significantly decreased in patients with accompanying CRS, more reduced in eosinophilic CRS (ECRS) than in non-eosinophilic CRS (NECRS), compared to non-CRS patients. In subjects with CRS, the expression of BDCA-3+cDC decreased in patients with accompanying AR; more reduced in multiple allergens sensitization. Consequently, the IF result showed CD4+ CD25+ Foxp3+ regulatory T cell expression was significantly decreased in CRS patients with AR compared to those without AR. Furthermore, the level of BDCA-3+cDC was also inversely related with preoperative CT scores, serum eosinophils and IgE levels. We suggest that BDCA-3+cDC may play an essential role in immunoregulation and induction of clinical tolerance. Reduced frequency of BDCA-3+cDC followed by impaired Treg expression in CRS patients with AR might reflect the mechanism of severe inflammation in patients of CRS combined with AR.
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Takamatsu, Hiroyuki, Yoshihiro Yakushijin, Koji Miyazaki, Akiyoshi Takami, Masahide Yamazaki, Hirokazu Okumura, and Shinji Nakao. "C-Terminal Defect of CD20 on T-Cell Leukemia/Lymphoma Cells: Implications for Resistance to Rituximab." Blood 112, no. 11 (November 16, 2008): 5267. http://dx.doi.org/10.1182/blood.v112.11.5267.5267.

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Abstract Rituximab is commonly used for treatment of B-cell leukemia/lymphoma and its efficiency on CD20+ B-cell malignancies has been established. On the other hand, the effect of rituximab on CD20+ T cell leukemia/lymphoma is unclear. Two patients CD20+ T-cell malignancy (1 with T-cell prolymphocytic leukemia (T-PLL) and 1 with peripheral T-cell lymphoma, unspecified (PTCL-u)) were recently treated with rituximab without appreciable effects. The treatment failure prompted a study of the mechanisms underlying the resistance to rituximab therapy using leukemia/lymphoma cells of these patients and another CD20+ T-PLL patient. Patient 1: A 68-year old Japanese male was diagnosed as having T-PLL (small cell variant) characterized by CD2+CD3+CD4− CD5+CD8+CD20+TCR-Vβ8+. Southern blotting of these T-PLL cells showed a TCR-β gene rearrangement. The systemic lymphadenopathy and high-fever of the patient were ameliorated by the administration of prednisolone (20 mg/d). Rituximab was administered weekly, but no clinical improvement was observed. In vitro treatment of the T-PLL cells with rituximab did not show any complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC). Patient 2: A 75-year old Japanese male was diagnosed as having T-PLL (small cell variant) with a phenotype of CD2+CD3+CD4+CD5+CD8+CD20+. Southern blotting of these T-PLL cells showed a TCR-β gene rearrangement. The patient is being followed without treatment because his pancytopenia is non-progressive. Patient 3: A 67-year old Japanese male developed a left thigh tumor which proved to be PTCL-u. The phenotype of lymphoma cells was CD2+CD3−CD4−CD5−CD8+CD20+ and Southern blotting of these cells showed a TCR-β gene rearrangement. The patient’s PTCL-u was refractory to CHOP and rituximab plus EPOCH therapy. The reactivity of various monoclonal Abs specific to CD20 molecules against these patients’ leukemia/lymphoma cells is summarized in Table 1. CD20 molecules of these 3 patients’ leukemia/lymphoma cells were detectable by flow cytometry using anti-CD20 mAbs (L27 and rituximab) and also by Western blotting using anti-CD20 mAbs which recognize N-terminal region of CD20. However, the CD20 molecules could not be revealed either by immunohistochemistry using anti-CD20 mAbs (L26) or by Western blotting using anti-CD20 mAbs which recognize C-terminal region of CD20. The sequence of the full-length CD20 cDNA derived from Patient 1’s T-PLL cells proved to be intact. These results indicate that the CD20 molecules of the 3 patients’ leukemia/lymphoma cells have defects in the cytoplasmic C-terminal region which may impair the cytotoxic effect of rituximab such as CDC and ADCC and the defect may be due to post translational changes such as phosphorylation of serine and threonine residues. Table 1. Reactivity to different Abs specific to CD20 Pt Age Gender L27 (FACS) Rituximab (FACS) L26 (IHC) C-terminal Ab (WB) N-terminal Ab (WB) FACS, flow cytometry; IHC, immunohistochemistry; WB, Western blotting; +, positive; −, negative; ND, not determined 1 68 M + + − − + 2 75 M + + − − + 3 67 M + ND − − +
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Abbott, Daniel, Steven Kroft, Maria Hintzke, Luis Carrillo-Polanco, Ashley Cunningham, John Astle, Vasiliki Leventaki, and Alexandra Harrington. "Immunophenotypic Analysis of Peripheral T-Cell Lymphomas: A Single-Center Retrospective Review of Flow Cytometric Analysis." American Journal of Clinical Pathology 152, Supplement_1 (September 11, 2019): S109. http://dx.doi.org/10.1093/ajcp/aqz121.012.

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Abstract Background Peripheral T-cell lymphomas (PTCLs) are heterogenous, mature T-cell neoplasms that are a diagnostic challenge, requiring a combination of morphologic assessment and ancillary studies. Flow cytometry (FC) is a tool used routinely in lymphoma diagnosis; however, most analyses are limited to B-cell evaluation and pathologists generally lack experience evaluating for PTCL. We aimed to describe the immunophenotypic aberrancies observed by FC in PTCL. Design PTCLs with FC were collected, excluding primary leukemic processes. Four- and eight-color FC data were reanalyzed with the following antigens (when available): CD2, CD3, CD4, CD5, CD7, CD8, CD30, CD45, CD45RO, CD56, and CD57. Lymphoma cells were compared to normal T cells and an isotype control. Antigen expression was defined as >20%. Results Thirty-eight cases were analyzed (29 males, 9 females, 6-86 years, median 62 years), including 29 PTCLs NOS, 4 angioimmunoblastic T-cell lymphomas (AITLs), 3 anaplastic large cell lymphomas, 1 δγ-TCL, and 1 hepatosplenic TCL from 15 bone marrows, 14 lymph nodes, 6 bloods, 2 fluids, and 1 skin. Twenty cases were CD4+, 4 were CD8+, 3 were dual +, and 10 were dual –. Thirty-seven cases (97%) showed global aberrant antigen patterns, median 4 aberrancies/case (1-8). Lymphoma cells accounted for 0.07% to 68% (median 2.6%) of total events. Aberrant CD7 expression was present in 34 of 38 (89%) and was underexpressed in 22 of 34 (65%). CD3 and CD5 were aberrant in 79% of cases each, with two-thirds showing underexpression. CD2 and CD45RO were aberrant in two-thirds of PTCLs, with overexpression in 61% and 92% of those cases, respectively. One AITL showed no aberrancies. Conclusions Nearly all PTCLs show immunophenotypic aberrancy compared to normal T cells. Most commonly, PTCL showed aberrant underexpression of CD7, CD3, and CD5 and overexpression of CD2 and CD45RO. Our data support FC panels with CD2, CD3, CD4, CD5, CD7, CD8, and CD45RO to optimize recovery of aberrant T cells.
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Tjønnfjord, G. E., O. P. Veiby, R. Steen, and T. Egeland. "T lymphocyte differentiation in vitro from adult human prethymic CD34+ bone marrow cells." Journal of Experimental Medicine 177, no. 6 (June 1, 1993): 1531–39. http://dx.doi.org/10.1084/jem.177.6.1531.

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Pluripotent lymphohematopoietic stem cells are probably confined to bone marrow cells expressing CD34 surface molecules. To investigate the capacity of adult human CD34+ bone marrow cells to differentiate along the T lymphoid lineage, we plated purified CD34+ cells from healthy adults in liquid culture on adherent thymic stromal cells prepared from HLA- or blood group-mismatched postnatal thymic tissue. We show that purified CD34+CD3-CD4-CD8- bone marrow cells contained progenitors with the ability to differentiate into CD4+ and CD8+ T lymphocytes expressing surface (s)CD3 and T cell receptor alpha/beta in vitro. These progenitors were found in the CD34+CD2+sCD3-CD4-CD8-, CD34+CD7+sCD3-CD4-CD8-, and CD34+CD2+CD7+sCD3-CD4-CD8-, as well as in the CD34+CD2-sCD3-CD4-CD8-, CD34+CD7-sCD3-CD4-CD8-, and CD34+CD2-CD7-sCD3-CD4-CD8- subsets, indicating that T lymphocyte progenitors sensitive to signals mediated by thymic stroma in vitro are not restricted to CD34+ cells already coexpressing early T lymphocyte-associated markers. Finally, we show that T lymphopoiesis was enhanced by c-kit ligand.
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Lukens, Michaël V., Debby Kruijsen, Frank E. J. Coenjaerts, Jan L. L. Kimpen, and Grada M. van Bleek. "Respiratory Syncytial Virus-Induced Activation and Migration of Respiratory Dendritic Cells and Subsequent Antigen Presentation in the Lung-Draining Lymph Node." Journal of Virology 83, no. 14 (May 6, 2009): 7235–43. http://dx.doi.org/10.1128/jvi.00452-09.

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ABSTRACT In the respiratory tract, different dendritic cell (DC) populations guard a tight balance between tolerance and immunity to infectious or harmless materials to which the airways are continuously exposed. For infectious and noninfectious antigens administered via different routes, different subsets of DC might contribute during the induction of T-cell tolerance and immunity. We studied the impact of primary respiratory syncytial virus (RSV) infection on respiratory DC composition in C57BL/6 mice. We also tracked the migration of respiratory DC to the lymph nodes and studied antigen presentation by lung-derived and lymph node-resident DC to CD4+ and CD8+ T cells. We observed a massive influx of mainly CD103− CD11bhigh CD11c+ conventional DC (cDC) and plasmacytoid DC during the first 7 days of RSV infection, while CD103+ CD11blow CD11c+ cDC disappeared from the lung. The two major subsets of lung tissue DC, CD103+ CD11blow CD11c+ and CD103− CD11bhigh CD11c+ cDC, both transported RSV RNA to the lung-draining lymph node. Furthermore, these lung-derived cDC subsets as well as resident LN DC, which did not contain viral RNA, displayed viral antigen by major histocompatibility complex class I and class II to CD8+ and CD4+ T cells. Taken together, our data indicate that during RSV infections, at least three DC subsets might be involved during the activation of lymph node-homing naïve and memory CD4+ and CD8+ T cells.
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Dissertations / Theses on the topic "CDC"

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Hansson, Alexander, and Andreas Petersson. "Mappningsstrategi på IKEA:s CDC-lager i Torsvik." Thesis, Jönköping University, JTH, Industrial Engineering and Management, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-939.

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This study has been assigned by Bengt Hellman who works at the logistic department at IKEA Torsvik just outside of Jönköping. The task has been to develop a new picking strategy for the Oversize area in the CDC-Warehouse. The reason why IKEA wants a new strategy is because they want to minimize the route length for the forklifts when collecting the orders.

By evaluating the current strategies on other areas in the CDC-storehouse, study literature within this subject and look at restrictions for the storing of goods, we have analyzed how the Oversize area works today. We compared the gathered information, to how it should be done according to the literature to be able to work out a new functional strategy.

Today, IKEA does not have a working strategy for the oversize area because of lack of time and because all the power has been put on other areas were sales rates are currently higher. This have led to lack of organisation at the Oversize area and items are just put were there is space without first analysing were it should be placed.

The strategy that we have worked out and introduced to IKEA builds on easiness of understanding the layout, the employees shall know why an item is placed where it is. We have also analyzed which items that are frequently ordered with each other. We have put weight on trying to keep those items as close as we can to minimize the route length for the forklifts. To help IKEA with reorganizations in the future we have made it as easy as we could to move high- and low frequently items around and also introducing new articles in the storehouse, this by the reason that sales rate can change drastically when a new sales campaign is initiated by IKEA


Detta examensarbete är utfört på önskemål av Bengt Hellman som arbetar på logistikavdelningen på IKEA Torsvik utanför Jönköping. Arbetet har gått ut på att ta fram ett nytt förslag på hur de skall placera sina artiklar på plocknivå (vad IKEA kallar för mappning) inne på Oversize avdelningen på IKEA:s CDC-lager. Anledningen till detta är att IKEA vill minska sina körsträckor för plockarna inne på lagret och därmed öka effektiviteten.

Genom att studera befintliga mappningsstrategier som redan finns på övriga avdelningar på CDC-lagret, litteraturstudier och titta på vilka begränsningar som finns inne på lagret så har vi analyserat nuläget mot teori för att sedan kunna ta fram en ny strategi för hur en fungerande mappning skulle kunna se ut.

I dag så finns det inte någon väl utarbetat strategi för mappningen på Oversize avdelningen, detta på grund av att andra avdelningar prioriterats på grund av att de säljer mycket mer i dagsläget. Detta har även medfört att den huvudsakliga uppdelning som fanns tidigare på Oversize avdelningen med affärsområden har fått stå åt sidan på grund av tidsbrist och artiklar har placerats in där det finns plats istället för att analysera var de kan placeras bäst.

Det nya förslaget som vi presenterar för IKEA bygger på att det skall vara enkelt att förstå layouten, plockarna skall veta varför en artikel finns där den finns. Vi har även tagit stor hänsyn till vad som säljs med vad och försökt placera dessa artiklar i närheten av varandra för att på så sätt minska körsträckorna. Vi har även haft i åtanke att det skall vara enkelt att placera om hög och lågfrekventa artiklar samt nyheter inne på lagret då försäljningsvolym påverkas väldigt mycket utav olika kampanjer som IKEA har.

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Ni, Tao. "Structural and functional study of MACPF/CDC superfamily proteins." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:50793dea-6aa6-4922-b7d8-43c50079639b.

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The thesis mainly focuses on structural study of proteins in membrane attack complex- perforin/cholesterol-dependent cytolysins (MACPF/CDC) superfamily, in particular, Astrotactins from human and perforin-like proteins (PLPs) from Toxoplasma and Plasmodium. Both of these subfamily proteins are implicated in human diseases and structurally uncharacterised before. Astrotactins (ASTNs) have been shown to play a crucial role in enabling neural migration along glial fibres. While ASTN1 directly forms contacts between the neuron and the fibre, ASTN2 is responsible for extracting ASTN1 from contacts at the lagging edge of the cell and recycling them to the leading edge. ASTN2 is associated with endosomes, with the majority of its structure (at the C-terminus) projecting into their lumen, anchored by a pair of transmembrane –-helices. Here we present the structure of this "endodomain" region of ASTN2, and find it to consist of a unique combination of polypeptide folds comprising a membrane attack com- plex/perforin (MACPF) domain, an EGF-like domain, a previously-unobserved form of fibronectin type III (Fn(III)) domain and an annexin-like domain. Taken together, the structural characterisation provides a framework for better understanding the mechanism of the ASTNs and related proteins in neural and other forms of vertebrate development. Perforin-like proteins from Toxoplasma and Plasmodium (TgPLP1 and PPLPs) are critical for normal life cycle progression of these parasites, and knockout out of any of them results in significant defects in their life cycle, entrapping the parasites within the host cells and thus limiting their ability to egress. Here we present the crystal structures of TgPLP1 MACPF domain and C-terminal domain at 2.0 Å and 1.1 Å, respectively. We also presents the MACPF domain assembled in helical and hexameric ring form, which indicates the possibility of pore-formation by 6 subunits. This is the first structure of perforin-like protein from Apicomplexan parasites and provides a structural basis to elucidate the function of PLPs in toxoplasmosis and malaria pathogenesis. The final section is a continuation of a previous study in our lab on pleckstrin homology (PH) domain of kindlins. We determined the crystal structure of kindlin-3 PH domain and characterised its lipid and membrane binding properties. Using nanodiscs incorporated with different lipids as model membrane system to study the interaction between inositol phosphate lipids and kindlin-3 PH domain, together with molecular dynamic simulation studies (in collaboration with Mark Sansom's group, University of Oxford), we propose that a subset of PH domains is able to bind to multiple inositol phosphates simultaneously and so via an avidity effect have its interaction with target membranes strengthened.
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Patala, Anne Havilah. "Discordance of Drug Susceptibility Test Data between the CDC Mycobacteriology Laboratory and Local Public Health Laboratories Participating in Tuberculosis Clinical Trials, TBTC, CDC." Digital Archive @ GSU, 2011. http://digitalarchive.gsu.edu/iph_theses/171.

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BACKGROUND: Multi drug resistant Tuberculosis (MDR-TB) is a serious public health concern in many parts of the world. As per the WHO- 2010 global report on Surveillance and response 3.6% of all incident TB cases globally are multidrug resistant. In this regard, there is an increasing demand for timely, reliable and comprehensive drug susceptibility testing (DST) as MDR-TB surveillance is being geared up. The intent of this analysis is to determine whether there is a need to continue routine confirmatory DST testing at CDC in addition to just sending the isolates for genotyping. Analysis is done by measuring the discordance between the results of laboratory DST at CDC and the local labs drug type, drug testing concentrations, and study sites. METHODS: The data for this analysis was provided by the Tuberculosis Trials Consortium (TBTC), CDC. Data for this analysis was collected over nearly two decades (1993-2011), gathered from 7 clinical trials. Discordance between the local and CDC lab DST results was measured using Kappa statistic. Sensitivity and specificity analysis was done by taking the CDC DST lab results as the gold standard. Discordance levels were calculated by local sites and baseline drug resistance for each antibiotic in each study was measured. RESULTS: Average Kappa values for inter rater agreement for all the studies was 0.6444 whereas the overall level of discordance across all studies is 7.786%. Drug resistance at baseline was highest for Isoniazid and Streptomycin (except Study 23 and 22). CONCLUSION: Though the current results show few DST result discordances between local and CDC labs, it is better to continue to send isolates to the centralized lab (CDC) in view of the worldwide threat of drug resistant TB epidemic, the recommendations of the current literature and the benefits of reliable confirmatory testing services and availability of other molecular diagnostic methods.
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Gordon, Colin B. "Molecular genetics of the cdc 22 gene of Schizosaccharomyces pombe." Thesis, University of Edinburgh, 1985. http://hdl.handle.net/1842/14920.

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Fisher, Daniel Leslie. "Molecular characterization of the fission yeast cyclin B homologue, cdc 13." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308658.

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Moissenet, Didier. "Bacille CDC GROUP IVc-2 : caractérisation, phylogénie, épidémiologie, sensibilité aux antibiotiques." Paris 5, 2006. http://www.theses.fr/2006PA05N05S.

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CDC Group IVc-2 est un bacille à Gram négatif, aérobie strict, mobile grâce à une ciliature péritriche, oxydase et catalase positives et non fermentant. Connu depuis les années 80, il a d'abord été rapproché de Bordetella bronchiseptica puis parfaitement différencié biochimiquement de cette espèce en 1986 par Pickett (87). Sa position taxonomique longtemps indéterminée a été précisée en 1999 (74, 83, 116) et nous y avons contribué (74). Bactérie de l'environnement hydrique (7, 63, 82). .
Our study of CDC Group IVc-2 began in 1995 with the report of five bacteriema at Trousseau hospital (APHP). Genotyping with RAPD, used for the first time for this species, showed a single pattern. Pulsed field gel electrophoresis, applied to Trousseau isolates and other French isolates, was unsuccessful since DNA was degraded. These isolates remained undistinguished after genotyping with PCR-ribotyping, PCR-RFLP, IRS-PCR. Surprisingly, all the strains obtained from American (ATCC) and Belgian (LMG) collections were easily distinguished by RAPD. We contributed to the taxonomic study of CDC Group IVc-2 named Ralstonia paucula in. .
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Funnell, Tyler. "Transcriptomic consequences of RNA processing disruption via a novel CDC-like kinase inhibitor." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/51614.

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RNA splicing is a process by which introns are excised from precursor mRNA. Variations in the segments removed — and the resulting mRNA molecule — may result in gene transcripts with differing and even opposing functions. The mechanisms involved in RNA splicing are tightly regulated, the disruption of which has been implicated in several human diseases including cancer. This presents the RNA splicing machinery as a potential therapeutic target. However, the effects of systematic splicing modulation through pharmaceutical intervention remain under explored. A thorough understanding of splicing can be investigated through controlled disruption of the molecular machinery. The Takeda Pharmaceutical Company Limited (Osaka, Japan) has recently developed a novel compound that inhibits the CDC-like family of kinases, which regulate key splicing factors. Although splicing inhibitors have already been published, their effects on the RNA splicing landscape have not been systematically described. The creation of a novel splicing inhibitor presents the opportunity to perform a methodical analysis of transcriptomic response to RNA processing inhibition using modern RNA sequencing and analysis methods. It is demonstrated, using the Takeda compound, that restricting the function of CDC-like kinases perturbs RNA splicing in both malignant and normal cells in a dose dependent manner. Post-treatment changes in splicing patterns revealed that these changes are mainly due to inefficient recognition of RNA splice sites. Splicing factors were among the earliest responders to treatment, indicating splicing autoregulatory mechanisms are sensitive to changes in splicing efficiency. Downstream effects were seen as dose-dependent changes in gene expression regulation, and down-regulated genes were enriched for splicing factors. Treatment also resulted in increased generation of conjoined gene transcripts — RNA molecules transcribed from at least two different genes, likely caused by transcriptional read-through. This revelation points to a previously undescribed role for CDC-like kinases in RNA processing.
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Fava, Marina Dubois. "Aplicação das normas do CDC aos contratos interempresariais: a disciplina das cláusulas abusivas." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/2/2132/tde-01122010-154105/.

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O presente estudo tem por objetivo demonstrar a necessidade de se tutelar a desigualdade substancial existente nas relações contratuais celebradas entre empresários, quando uma das partes, ainda que profissional, encontrar-se em situação de dependência econômica, favorecendo o abuso da parte contrária na situação concreta. O cerne do trabalho gira em torno do problema das cláusulas abusivas no âmbito dos contratos interempresariais. Busca-se demonstrar que, nas hipóteses em que não for possível repreendê-las por meio da aplicação do Código Civil ou da Lei Antitruste, seria possível equiparar o contratante vulnerável, sujeito a um abuso por parte de seu parceiro contratual, aos consumidores, para fins de aplicação dos dispositivos do Código de Defesa do Consumidor CDC ao contrato em questão. Para tanto, são analisados os conceitos de empresário, de consumidor tendo em vista as três principais correntes doutrinárias existentes no ordenamento pátrio e de dependência econômica. Especificamente em relação à definição de consumidor, tenta-se demonstrar que, nos dias de hoje, a Teoria Finalista Aprofundada parece ser a que melhor atende à necessidade de se buscar a solução mais justa no caso concreto, sem, contudo, banalizar a aplicação do CDC. Por fim, faz-se uma análise da jurisprudência brasileira sobre o tema, com o objetivo de delimitar os critérios para a incidência do CDC em contratos interempresariais, bem como os principais casos em que o conceito de consumidor-equiparado tem prevalecido nos litígios decorrentes de tais contratos.
The objective of the present study is to demonstrate the need of instructing the substantial inequality existing in contractual relations signed between businessmen, when one of the parties, although still professional, finds itself in a situation of economic dependence, favoring the abuse of the counterpart in the real situation. The core of this work involves the problem regarding abusive clauses in the scope of inter-business contracts. It seeks to demonstrate that, in hypothesis where it is not possible to reprehend them by means of application of the Civil Code or Antitrust Act, it would be possible to match the vulnerable contracting party, subject to an abuse by its contractual partner, to the consumers, for purposes of application of the provisions in the Consumer Defense Code CDC to the contract in question. To do so, it analyzes the concepts of businessman and consumers considering the three main doctrinaire schools of thought existing in the country system and economic dependence. Specially in relation to the definition of consumers, it attempts to demonstrate that, nowadays, the In-depth Finalist Theory seems to be the best theory that meets the need of searching for the more righteous solution in the real case, without, however, trivializing the application of the CDC. At last, an analysis of Brazilian jurisprudence is made on the subject, aiming to delimitate the criteria for the incidence of CDC in inter-business contracts as well as the main cases in which the concept of consumer has prevailed in such contracts for one of the parties.
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Small, Lawrence Edward. "PAR Proteins Regulate CDC-42-Dependent Myosin Dynamics During C. elegans Zygote Polarization." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1461086954.

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Lai, Man-kit, and 黎文傑. "Junior secondary pupils' learning in the biological concepts included in the CDC science (Forms I-III) syllabus 1986 and prerequisite forthe CDC human biology (Secondary IV-V) syllabus 1987 of Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1988. http://hub.hku.hk/bib/B31955794.

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Books on the topic "CDC"

1

Coach Drivers Club of Great Britain. CDC yearbook. Yate: CDC, 1999.

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Instruments, Texas. CDC clock-distribution circuits. [S.l.]: Texas Instruments, 1994.

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Board, National Institutes of Health (U S. ). Patent Policy. NIH/ADAMHA/CDC technology transfer. [Atlanta, Ga.?]: The Centers, 1992.

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Centers for Disease Control (U.S.), ed. CDC reports on injury control. [Atlanta, GA: Dept. of Health & Human Services, Public Health Service, Centers for Disease Control, 1985.

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Ogden, Horace G. CDC and the smallpox crusade. [Atlanta, Ga.]: U.S. Dept. of Health and Human Services, Public Health Service, Centers for Disease Control, 1987.

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Ogden, Horace G. CDC and the smallpox crusade. [Atlanta, Ga.?]: U.S. DHHS, PHS, Centers for Disease Control, 1987.

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Association, American Public Health, and Center for Disease Control (U.S.), eds. APHA-- CDC recommended minimum housing standards. Washington, D.C: American Public Health Association, 1986.

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National Center for Injury Prevention and Control (U.S.). CDC injury research agenda: 2009-2018. Atlanta, Ga: U.S. Dept. of Health and Human Services, Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, 2009.

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HHS/CDC-Ethiopia. HHS/CDC-Ethiopia: 2001-2003 report. Addis Ababa, Ethiopia: HHS/CDC-Ethiopia, 2004.

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Pontus, Aspenstrøm, ed. The pombe Cdc 15 homology proteins. Austin, Tex: Landes Bioscience, 2009.

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Book chapters on the topic "CDC"

1

Lackner, K. J., and D. Peetz. "CDC-Referenzmethode." In Springer Reference Medizin, 548. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_696.

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Lackner, K. J., and D. Peetz. "CDC-Referenzmethode." In Lexikon der Medizinischen Laboratoriumsdiagnostik, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_696-1.

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Steele, Guy L., Xiaowei Shen, Josep Torrellas, Mark Tuckerman, Eric J. Bohm, Laxmikant V. Kalé, Glenn Martyna, et al. "CDC 6600." In Encyclopedia of Parallel Computing, 227. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-0-387-09766-4_2107.

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Ibbett, R. N., and N. P. Topham. "The CDC Series." In Architecture of High Performance Computers, 156–79. New York, NY: Springer New York, 1989. http://dx.doi.org/10.1007/978-1-4899-6712-1_9.

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Baumann, Chris, Hume Winzar, and Doris Viengkham. "CDC Over Time." In Confucianism, Discipline, and Competitiveness, 147–98. NewYork, NY : Routledge, 2020. | Series: Routledge studies in international business and the world economy: Routledge, 2019. http://dx.doi.org/10.4324/9781351062220-4.

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Ibbett, R. N., and N. P. Topham. "The CDC Series." In Architecture of High Performance Computers, 156–79. London: Macmillan Education UK, 1989. http://dx.doi.org/10.1007/978-1-349-19757-6_9.

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Schneck, Paul B. "The CDC 6600." In The Kluwer International Series in Engineering and Computer Science, 35–51. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4615-7957-1_3.

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Knowlton, Christin A., Michelle Kolton Mackay, Tod W. Speer, Robyn B. Vera, Douglas W. Arthur, David E. Wazer, Rachelle Lanciano, et al. "Complement-Dependent Cytotoxicity (CDC)." In Encyclopedia of Radiation Oncology, 133. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-540-85516-3_678.

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Churiwala, Sanjay, and Sapan Garg. "Clock Domain Crossing (CDC)." In Principles of VLSI RTL Design, 73–89. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-9296-3_4.

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Schneck, Paul B. "The CDC STAR-100." In The Kluwer International Series in Engineering and Computer Science, 99–117. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4615-7957-1_5.

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Conference papers on the topic "CDC"

1

Наджафова, В. А. к. "Оценка нарушений субпопуляций лимфоцитов у детей с железодефицитной анемией." In General question of world science. Наука России, 2021. http://dx.doi.org/10.18411/gq-31-07-2021-03.

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Статья посвящена проблеме нарушения иммунитета у детей с железодефицитной анемией (ЖДА), проживающих в Азербайджане. Были выявлены более низкие показатели клеточного иммунитета (CD3, CD4, CD8). Относительное количество клеток CD3 в общей группе детей с ЖДА составило 52,7±4,35%, в контрольной группе - 62,6±5,49%, р<0,05. Проведенные исследования выявили положительную корреляцию клеток CD3, CD4, CD8 с гемоглобином и сывороточным железом. Результаты высокой силы связи коэффициента корреляции сывороточного железа с относительным количеством клеток CD3 и CD4 в общих группах детей с ЖДА (r = 0,8) показали, что дефицит железа играет большую роль для активности клеточного иммунитета. Таким образом, в статье показано ослабление как врожденного (NK-CD56), так и приобретенного (CD3, CD4, CD8) компонентов клеточного иммунитета. Полученные результаты могут быть оценены как нарушение иммунного баланса, связанное с недостаточностью клеточного иммунитета у детей с ЖДА.
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Ni, Fan, Xing Lin, and Song Jiang. "SS-CDC." In SYSTOR '19: The 12th ACM International Systems and Storage Conference. New York, NY, USA: ACM, 2019. http://dx.doi.org/10.1145/3319647.3325834.

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Rana, Seema, and Rajiv Tangri. "Anaplastic large cell lymphoma ALK negative vs. peripheral T cell lymphoma (NOS) - diagnostic dilemma." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685354.

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Middle aged female presented with generalised lymphadenopathy and fever for last one month. Peripheral blood findings were within normal limits. There was no extra nodal involvement. FNAC performed initially from a cervical node suggested possibility of Hodgkin’s lymphoma and a whole node biopsy was performed. Histopathogical examination revealed effaced nodal architecture and a polymorphous population of lymphocytes, plasma cells, neutrophils and scattered large mononuclear cells with prominent nucleolus. An initial panel of CD3, CD20, LCA, CD15, CD30 and PAX5 was performed. The large atypical cells were positive for LCA, CD3 and CD30 with variable positivity for CD15. CD 30 showed Golgi and membranous staining. These large atypical cells were negative for PAX5 and CD20. In view of above findings, Hodgkin’s lymphoma was ruled out and a possibility of Non- Hodgkin’s lymphoma was considered. Further IHC markers were performed which included CD2, CD5, CD7, EMA, Alk, CD10 and KI67. CD5 showed variable positivity. The cells of interest were negative for CD2, CD7, ALK and EMA. Ki 67 index was 70-80%. Overall histological and IHC findings favoured Alk negative Anaplastic large cell lymphoma. Differential diagnosis considered was peripheral T cell lymphoma (NOS). Hodgkin’s lymphoma, peripheral T cell lymphoma (NOS) and anaplastic large cell lymphoma share common histomorphological findings. With careful analysis of Immunohistochemistry, it is easier to categorise Hodgkin’s lymphoma. ALK negative anaplastic large cell lymphoma and peripheral T cell lymphoma (NOS) are difficult to categorise and show overlapping features. We in this case have discussed clinical, histomorphological and IHC pattern of Alk negative Anaplastic large cell lymphoma.
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"Special CDC sessions." In 2008 47th IEEE Conference on Decision and Control. IEEE, 2008. http://dx.doi.org/10.1109/cdc.2008.4738575.

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"Welcome to the 45th IEEE CDC, Invitation by the CDC Chair." In Proceedings of the 45th IEEE Conference on Decision and Control. IEEE, 2006. http://dx.doi.org/10.1109/cdc.2006.376801.

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Yu, Zitong, Yunxiao Qin, Hengshuang Zhao, Xiaobai Li, and Guoying Zhao. "Dual-Cross Central Difference Network for Face Anti-Spoofing." In Thirtieth International Joint Conference on Artificial Intelligence {IJCAI-21}. California: International Joint Conferences on Artificial Intelligence Organization, 2021. http://dx.doi.org/10.24963/ijcai.2021/177.

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Face anti-spoofing (FAS) plays a vital role in securing face recognition systems. Recently, central difference convolution (CDC) has shown its excellent representation capacity for the FAS task via leveraging local gradient features. However, aggregating central difference clues from all neighbors/directions simultaneously makes the CDC redundant and sub-optimized in the training phase. In this paper, we propose two Cross Central Difference Convolutions (C-CDC), which exploit the difference of the center and surround sparse local features from the horizontal/vertical and diagonal directions, respectively. It is interesting to find that, with only five ninth parameters and less computational cost, C-CDC even outperforms the full directional CDC. Based on these two decoupled C-CDC, a powerful Dual-Cross Central Difference Network (DC-CDN) is established with Cross Feature Interaction Modules (CFIM) for mutual relation mining and local detailed representation enhancement. Furthermore, a novel Patch Exchange (PE) augmentation strategy for FAS is proposed via simply exchanging the face patches as well as their dense labels from random samples. Thus, the augmented samples contain richer live/spoof patterns and diverse domain distributions, which benefits the intrinsic and robust feature learning. Comprehensive experiments are performed on four benchmark datasets with three testing protocols to demonstrate our state-of-the-art performance.
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"2004 CDC organizing committee." In 2004 43rd IEEE Conference on Decision and Control (CDC) (IEEE Cat. No.04CH37601). IEEE, 2004. http://dx.doi.org/10.1109/cdc.2004.1429208.

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Zaychenko, Sergiy, Pavlo Leshtaev, Bogdan Gureev, and Maksym Shliakhtun. "Structural CDC analysis methods." In 2016 IEEE East-West Design & Test Symposium (EWDTS). IEEE, 2016. http://dx.doi.org/10.1109/ewdts.2016.7807671.

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"Virtualization of CDC 2020." In 2020 59th IEEE Conference on Decision and Control (CDC). IEEE, 2020. http://dx.doi.org/10.1109/cdc42340.2020.9303874.

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"CDC 2020 Associate Editors." In 2020 59th IEEE Conference on Decision and Control (CDC). IEEE, 2020. http://dx.doi.org/10.1109/cdc42340.2020.9304399.

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Reports on the topic "CDC"

1

Chitanvis, Maneesha Elizabeth. LANL biosurveillance tools at CDC. Office of Scientific and Technical Information (OSTI), May 2017. http://dx.doi.org/10.2172/1361464.

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Yamada, R., J. Hawtree, K. Kaczar, R. Leverence, K. McGuire, C. Newman-Holmes, E. E. Schmidt, and J. Shallenberger. CDC field mapping device - ''ROTOTRACK''. Office of Scientific and Technical Information (OSTI), October 1985. http://dx.doi.org/10.2172/6459052.

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Galea, Sandro, Lawrence Gostin, Alan B. Cohen, and Nicole Lurie. Eight Operational Suggestions for a Renewed CDC. Milbank Memorial Fund, January 2021. http://dx.doi.org/10.1599/mqop.2021.0105.

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Menon, Shantanu, Aruna Pandey, Kushagra Merchant, and Satender Rana. Community Development Centre (CDC): A covenant with the Baiga (tribe). Indian School Of Development Management, August 2022. http://dx.doi.org/10.58178/2208.1004.

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"This case engages with the journey of Community Development Centre (CDC), a small non-profit organization operating in the Mahakaushal region of Madhya Pradesh for over two decades. The case demonstrates how CDC has created a resilient and responsive organizational culture in a remote and resource-starved environment to address multiple developmental challenges of the region and in particular, of the most marginalized Baiga tribe within it. It underscores the importance of a firm conviction in the cause as a precondition of talent which works in such a context. It draws attention to the persistence and skill required to develop lasting relations of trust with the community and the challenges involved in balancing constructive contestation as well as support for the local and state administration. This case represents many similar small organizations that carry out credible and often pivotal work in their own contexts. Through the example of CDC, this case aims to build an appreciation of how nurturing such organizations is critical to give due share to those who remain invisible to the mainstream developmental discourse."
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Parsa, Z., and E. Courant. Guide to Accelerator Physics Program Synch - CDC Version. Office of Scientific and Technical Information (OSTI), January 1987. http://dx.doi.org/10.2172/1151180.

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Parsa, Zohreh. Guide to VAX, CDC, and IBM 3090 Third Edition. Office of Scientific and Technical Information (OSTI), May 1987. http://dx.doi.org/10.2172/1118914.

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Hoerger, Thomas, Joel Segel, Ping Zhang, and Stephen Sorensen. Validation of the CDC-RTI Diabetes Cost-Effectiveness Model. Research Triangle Park, NC: RTI Press, September 2009. http://dx.doi.org/10.3768/rtipress.2009.mr.0013.0909.

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Ferron, J. R. User`s manual for the CDC-1 digitizer controller. Office of Scientific and Technical Information (OSTI), September 1994. http://dx.doi.org/10.2172/10181403.

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Hollander, Attelia. Diagnostic Testing for COVID-19 Bridging Study for CDC EUA assays vs CDC Multiplex N1 FAM, N2 SUN, RNAse P ATTO 647 Assays. Office of Scientific and Technical Information (OSTI), February 2021. http://dx.doi.org/10.2172/1766983.

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Simpkins, Ali, A. Technical Review of SRS Dose Reconstrruction Methods Used By CDC. Office of Scientific and Technical Information (OSTI), July 2005. http://dx.doi.org/10.2172/881440.

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