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Dissertations / Theses on the topic 'CD8'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Thomas, Ian James. "Investigation of the differential effects of CD80 and CD86 costimulation on CD8 T cells." Thesis, University of Bristol, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424069.

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2

Eichelbauer, Dirk. "In-vitro-Untersuchungen zur Stimulation von humanen TZR-[alpha]/[beta]+-CD4-CD8-doppeltnegativen [TZR-alpha-beta-CD4-CD8-doppeltnegativen] T-Lymphozyten." [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=970313373.

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3

Cauchy, Pierre. "Rôle et contexte transcriptionnel du facteur de transcription Ets1 au cours transition CD4- CD8- à CD4+ CD8+ de la tymopoïèse αβ". Thesis, Aix-Marseille 2, 2010. http://www.theses.fr/2010AIX22135.

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ETS1 est un facteur de transcription (FT) spécifique transposé dans les leucémies aigües. Le rôle essentiel d'ETS1 a été décrit au cours de l'hématopoïèse, plus particulièrement dans la différenciation lymphocytaire T. Son expression temporelle coordonnée participe au contrôle des transitions du stade double négatif (DN) CD4-/CD8- au stade double positif (DP) CD4+/CD8+jusqu'au stade simple positif (SP) CD4+ ou CD8+. Au cours de l'ontogenèse T, ETS1 transactive notamment l'expression des chaînes β et α du récepteur des cellules T (TCR). Nous avons criblé à grande échelle les cibles d'ETS1 aux s

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4

Pinheiro, CatiÃssia Dantas. "CÃlulas CD3+, CD4+, CD8+, CD3-CD16+CD56+ e CD19+ em sangue perifÃrico de pacientes com hansenÃase e indivÃduos saudÃveis." Universidade Federal do CearÃ, 2013. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=16323.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>A hansenÃase Ã uma doenÃa granulomatosa, infecto-contagiosa causada pelo Mycobacterium leprae. Trata-se de uma infecÃÃo crÃnica com amplo espectro de respostas imunes celulares em humanos. Possui alto poder infectante e baixo poder patogÃnico. Este estudo tem como objetivo quantificar e comparar leucÃcitos e subpopulaÃÃes de linfÃcitos T totais (CD3+), T auxiliares (CD3+CD4+), T citotÃxicos (CD3+CD8+), B (CD19+) e NK (CD3-CD16+CD56+) em sangue perifÃrico de indivÃduos com hansenÃase e controles saudÃveis. Os pacientes foram prove

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Pinheiro, Catiússia Dantas. "Células CD3+, CD4+, CD8+, CD3-CD16+CD56+ e CD19+ em sangue periférico de pacientes com hanseníase e indivíduos saudáveis." reponame:Repositório Institucional da UFC, 2013. http://www.repositorio.ufc.br/handle/riufc/15425.

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PINHEIRO, Catiússia Dantas. Células CD3+, CD4+, CD8+, CD3-CD16+CD56+ e CD19+ em sangue periférico de pacientes com hanseníase e indivíduos saudáveis. 2013. 65 f. Dissertação (Mestrado em Patologia) - Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, 2013.<br>Submitted by denise santos (denise.santos@ufc.br) on 2016-03-09T13:41:07Z No. of bitstreams: 1 2013_dis_cdpinheiro.pdf: 775643 bytes, checksum: 2d4939ef2f883a155737695a2e7c759a (MD5)<br>Approved for entry into archive by denise santos(denise.santos@ufc.br) on 2016-03-09T15:22:37Z (GMT) No. of bitstreams: 1 2013_dis_cdpinheir

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6

Khan, Qasim. "Regulation of apoptosis in CD4§-CD8§- Ãß§+ T cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ29310.pdf.

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7

Tyznik, Aaron Jacob. "CD4+ T cell help for CD8+ T cell responses /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/8314.

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8

Behrendt, Anne. "Differential antigen dependency of CD4+ and CD8+ T cells." Diss., Ludwig-Maximilians-Universität München, 2014. http://nbn-resolving.de/urn:nbn:de:bvb:19-171521.

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9

Anand, Arthi. "Characterization of CD3+CD4-CD8- (double negative) T cells in patients with systematic lupus erythematosus (SLE)." Thesis, University College London (University of London), 2003. http://discovery.ucl.ac.uk/1445261/.

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Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disease characterized serologically by B cell hyperactivity and a panoply of autoantibodies against nuclear, cytoplasmic and cell surface antigens. It is thought that T cells are involved in this process and more recently it has been suggested that the CD4+ CD8+, i.e.double negative (DN) T cells, might be important. As a start to understanding the contribution of DN T cells to disease pathogenesis in SLE, the percentages of DN T cells were determined and it was found that otp but not y5 DNT cells were significantly increased in pati

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10

Freitag, Kimberly A. "Effects of Acute Nutritional Deprivation on Lymphocyte Subsets and Membrane Function in Cats." Thesis, Virginia Tech, 1998. http://hdl.handle.net/10919/46484.

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Identification of patients with suboptimal nutritional status allows for early treatment intervention. Currently, no definitive test of nutritional status exists. Therefore, this study was conducted to identify possible functional indicators of acute nutritional deprivation. The effects of total nutritional deprivation and subsequent refeeding on lymphocyte functions and subpopulations were examined in 23 healthy cats. Peripheral blood samples were analyzed at various times during fasting and refeeding periods. During the fasting period, decreases were observed in leukocyte number (day 4;

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11

Jiang, Janina Q. "The production of HIV suppressive factors by CD28, CD38 and HLA-DR subpopulations of CD8+ T cells." Thesis, University of Ottawa (Canada), 2001. http://hdl.handle.net/10393/9104.

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We have examined CD8+ sub-populations to determine whether these subsets are critical to the production of CD8+ T cell nonlytic factors. The production of the beta-chemokines MIP-1alpha, MIP-1beta and RANTES, and the chemoattractant cytokine IL-16 were measured in cells derived from 24 HIV-infected and 25 uninfected subjects. Asymptomatic HIV+ subjects (CD4 > 200/ul) produced significantly higher levels of MIP-1alpha and MIP-1beta from CD8+ T cells and some sub-phenotypes. Higher RANTES levels were produced by CD28-, CD38- and HLA-DR+/- sub-phenotypes. However, IL-16 was only modulated in the

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12

Rabenstein, Hannah. "Antigenabhängige und -unabhängige Proliferation von CD4- und CD8-T-Zellen." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-169430.

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13

Potthast, Kerstin. "Interaktion des humanen CD8 mit MHC Klasse I und CD3-TCR." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=967744253.

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14

Dembele, Bamory. "Mécanismes de l'aide lymphocytaire T CD4 aux cellules T CD8 mémoires." Paris 11, 2010. http://www.theses.fr/2010PA11T076.

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15

Zaragoza, Bruno. "Rôle des lymphocytes T CD4+ dans l'homéostasie des lymphocytes T CD8+." Paris 6, 2009. http://www.theses.fr/2009PA066313.

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Dans une première partie, nous nous sommes concentrés sur l’homéostasie des lymphocytes T CD4+. Nous montrons que le pourcentage de cellules T CD4+CD25+ parmi les cellules T CD4+ est indexé au nombre de cellules IL-2+. Nous avons découvert que la conversion des cellules T CD4+CD25- en cellules T CD4+CD25+ était possible mais inhibé par la présence de cellules T CD4+CD25+. Enfin, dans deuxième partie, nous avons étudié le rôle des lmphocytes T CD4+ dans l’homéostasie des lymphocytes T CD8+. Le co-transfert de cellules T CD4+ naïves accroît la prolifération dûe à la lymphopénie des cellules T CD

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16

Clement, Mathew. "The role of the CD8 co-receptor in CD8+ T-cell activation." Thesis, Cardiff University, 2013. http://orca.cf.ac.uk/47019/.

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CD8+ T-cells are essential for the immune control of pathogens and the natural eradication of cancer. CD8+ T-cells also play a major role in the pathogenesis of autoimmunity and alloreactivity. CD8+ T-cells recognize short peptide fragments (8-13 amino acids) presented at the target cell surface bound to Major Histocompatability Class I (MHCI) molecules. Tcell antigen recognition is unique in nature because it involves the binding of a single ligand (peptide–MHC [pMHC]) by two receptors (TCR and CD8). The CD8 glycoprotein, which serves as the coreceptor on MHCI-restricted T-cells, acts to enha

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17

Arévalo, Suárez Fernando, Sabino Portugal, Carlos Barreda, et al. "Enfermedad celíaca vs. atrofia villositaria serológicamente negativa: similitudes y diferencias histológicas y en el perfil inmunohistoquímico de linfocitos CD3, CD4, CD8 y CD56." Sociedad de Gastroenterología del Perú (SGP), 2016. http://hdl.handle.net/10757/617280.

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Existe un grupo de enteropatía conocidas como AVSN que pueden simular enfermedad celíaca. Objetivo: El objetivo de este estudio es describir los hallazgos histológicos y de inmunohistoquímica en pacientes con enfermedad celíaca y AVSN. Material y métodos: 15 biopsias de pacientes con enfermedad celíaca y 19 biopsias con AVSN fueron reexaminados. Se estudió características histológicas tales como atrofia severa, hiperplasia de criptas, número de células plasmáticas, número de eosinófilos y presencia de neutrófilos. Asimismo, a través de inmunohistoquímica se estudió la presencia de linfocitos C

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18

Köchling, Annabel. "Postoperative Komplikationen bei HIV-Patienten unter besonderer Berücksichtigung des CD4/CD8-Quotienten." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968081045.

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19

Yang, Jason D. "Antigen Specific CD4+ and CD8+ T Cell Recognition During Mycobacterium Tuberculosis Infection." eScholarship@UMMS, 2018. https://escholarship.umassmed.edu/gsbs_diss/968.

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Mycobacterium tuberculosis (Mtb) causes human tuberculosis, and more people die of it than of any other pathogen in the world. Immunodominant antigens elicit the large majority of T cells during an infection, making them logical vaccine candidates. Yet, it is still unknown whether these immunodominant antigen-specific T cells recognize Mtb-infected cells. Two immunodominant antigens, TB10.4 and Ag85b, have been incorporated into vaccine strategies. Surprisingly, mice vaccinated with TB10.4 generate TB10.4-specific memory CD8+ T cells but do not lead to additional protection compared to unvacci

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20

Li, Ming 1957. "Generation of CD8+ T cell immunity with help from CD4+ T cells." Monash University, Dept. of Pathology and Immunology, 2002. http://arrow.monash.edu.au/hdl/1959.1/8476.

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21

Cheng, Gordon W. "Functions of CD45 in TCR signaling in CD4§+CD8§+ double-positive thymocytes." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq29256.pdf.

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22

Hackenbroch, Jessica. "CD4⁺ and CD8⁺ naïve T-cell homeostasis in primary progressive multiple sclerosis." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112629.

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Multiple Sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system. The etiology of MS is unknown but many researchers believe that it is autoimmune mediated. This study investigated naive CD4+ and naive CD8+ T-cell homeostasis in patients with Primary Progressive Multiple Sclerosis and Relapsing Remitting Multiple Sclerosis. The naive T-cell compartment involves a balance between thymic production of naive T-cells, homeostatic proliferation and the delivery of death and survival signals. Naive T-cell production was quantified by measuring signal joint T-

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23

Lin, Ya-Ling. "CD4⁺/CD8⁺ T cells and macrophage-derived TNF-α in murine schistosomiasis". Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627622.

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24

Yang, Rui. "Role Of Interleukin-6 In Cd4 And Cd8 T Cell Effector Functions." ScholarWorks @ UVM, 2016. http://scholarworks.uvm.edu/graddis/654.

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IL-6 is an inflammatory cytokine that contributes to the pathogenesis of many immunological diseases including rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, allergic asthma, as well as the protection against infections caused by various pathogens. These are linked to its role in regulating CD4 T cell differentiation and effector function. Most of these functions are dependent on the IL-6-mediated signaling through the transcription factor Stat3. In this thesis, we identify a novel molecular mechanism by which IL-6 regulates CD4 T cell effector function. We show that I

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25

Cariou, Anne. "Spécificité de l'aide T CD4 lors de la réponse T CD8 mémoire." Paris 6, 2009. http://www.theses.fr/2008PA066730.

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26

URGELL, LAFONT PASCALE. "Evolution des populations lymphocytaires cd4+ et cd8+ dans le sang au cours de la polyarthrite rhumatoide : etude longitudinale a propos de 39 cas." Toulouse 3, 1992. http://www.theses.fr/1992TOU31005.

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27

Finch, Rosalynde J. "Regulation of interleukin-2 gene transcription in CD8 positive cells /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/8352.

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28

Haipek, Katia. "Avaliação das subpopulações de linfócitos T CD4+, linfócitos T CD8+ e da razão CD4+/CD8+ em gatos com gengivite crônica e infectados naturalmente pelo vírus da imunodeficiência dos felinos (FIV)." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/10/10136/tde-25052007-143025/.

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A gengivite crônica e intratável observada em gatos infectados pelo vírus da imunodeficiência felina (FIV) é um problema bastante freqüente na clínica de pequenos animais. O papel do FIV na etiologia da estomatite persistente ainda está por ser determinado. As manifestações orais são freqüentemente os primeiros sintomas observados em pacientes humanos infectados pelo HIV e podem ser usadas como indicadores da progressão da doença. O objetivo do presente estudo foi quantificar os linfócitos T CD4+, T CD8+ e a razão CD4+/CD8+ em uma colônia de gatos com gengivite crônica e naturalmente infectado

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29

Sun, Joseph C. "The role of CD4 T cell help during the CD8 T cell response /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/8334.

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30

Turqueti, Neves Adriana. "Recognition of renal cell carcinoma by CD8+ and CD4+ TCR-engineered T lymphocytes." Diss., lmu, 2011. http://nbn-resolving.de/urn:nbn:de:bvb:19-128858.

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31

Li, Li. "Induction and regulation of delayed type hypersensitivity by CD4 and CD8 T subsets." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq23017.pdf.

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32

Drews, Lisann Marie [Verfasser]. "Charakterisierung sekretorischer Lysosomen aus humanen CD4+ und CD8+ T-Zellen / Lisann Marie Drews." Kiel : Universitätsbibliothek Kiel, 2019. http://d-nb.info/1179184254/34.

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33

Waller, Edward Charles Patrick. "Characterisation of Human Cytomegalovirus-specific CD8+ CD45RA+ CD28- revertant memory T cells (TEMRA)." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612047.

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34

Sousa, Maria da Gloria Teixeira de. "Caracterização das funções dos linfócitos T CD4+ e T CD8+ na cromoblastomicose experimental." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-05012018-095528/.

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A cromoblastomicose é uma infecção fúngica subcutânea causada por fungos da família Dematiceae sendo o principal agente etiológico o fungo Fonsecaea pedrosoi (F. pedrosoi). Estes fungos induzem uma lesão crônica na pele de freqüente recidivas. O objetivo do trabalho foi avaliar alguns aspectos imunológicos na cromoblastomicose experimental através de dois modelos de infecção pelas vias: intraperitoneal (i.p.) e subcutânea (s.c.). No primeiro modelo de infecção pela via s.c. em camundongos BALB/c infectados com 106 conídios de F. pedrosoi, ocorreu a cura espontânea da infecção em aproximadament

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35

Drews, Lisann [Verfasser]. "Charakterisierung sekretorischer Lysosomen aus humanen CD4+ und CD8+ T-Zellen / Lisann Marie Drews." Kiel : Universitätsbibliothek Kiel, 2019. http://d-nb.info/1179184254/34.

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36

Takayama, Eiji. "Enhancement of Activation-Induced Cell Death by Fibronectin in Murine CD4[+]CD8[+] Thymocytes." Kyoto University, 2001. http://hdl.handle.net/2433/150598.

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37

Salou, Marion. "Implication des lymphocytes T CD8+ à répertoire restreint dans la sclérose en plaques." Nantes, 2014. http://archive.bu.univ-nantes.fr/pollux/show.action?id=e869cf43-0e5b-473b-a99c-81c495b4b59d.

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La Sclérose En Plaques (SEP) est une maladie autoimmune démyélinisante du Système Nerveux Central (SNC), dans laquelle les lymphocytes T (LT) CD4+ semblent jouer un rôle majeur. L'implication des LT CD8+ a été mise en évidence plus récemment, grâce à de nombreux arguments génétiques, neuropathologiques et immunologiques. Dans des lésions du SNC de patients, les LT CD8+ sont prédominants et ont une répartition oligoclonale, suggérant une infiltration ou une prolifération in situ dépendante d'un antigène. Pour savoir si ces cellules sont accessibles depuis le sang et/ou le liquide céphalorachidi

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Phothirath, Phoukham. "Génération de cellules T CD4+CD25+ suppressives induite par des lymphocytes T CD8+CD28- au cours de réactions leucocytaires mixtes autologues." Lyon 1, 2002. http://www.theses.fr/2002LYO1T195.

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La 4ème de couverture indique : "La réaction mixte lymphocytaire autologue (aMLR) permet l'étude des circuits de régulation du système immunitaire et correspond à la prolifération des lymphocytes T CD4+ suite à une stimulation par des cellules dendritiques autologues (aMLRs déficientes dans: maladie de Hodgkin, syndrome de Down, lupus érythémateux systématique, arthrite rhumatoi͏̈de, cirrhose biliaire primitive, etc). Les lymphocytes T CD8+CD28- sont des cellules régulatrices capables de suppression directe de l'allo- et la xéno-réactivité de lymphocytes T CD4+ et de rendre tolérogènes des cel

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Silva, Pedro Mário Lemos da. "Associação entre a atividade sexual e marcadores de imunidades adquirida em mulheres com AIDS em um município do Nordeste brasileiro." Universidade Federal do Maranhão, 2015. http://tedebc.ufma.br:8080/jspui/handle/tede/1026.

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Made available in DSpace on 2016-08-19T17:37:08Z (GMT). No. of bitstreams: 1 DISSERTACAO_PEDRO MARIO LEMOS DA SILVA.pdf: 1042037 bytes, checksum: 9398b2cf8b35f848832cef710c038521 (MD5) Previous issue date: 2015-04-30<br>INTRODUCTION:The Acquired Immunodeficiency Syndrome (Aids) comes along the years promoting inversion of the relation men/women in the age group of 13 to 19 years, committing mainly the reproductive life phase women. The sexuality, inherent upon human being, has in the expression of satisfaction of the sexual performance the possibility of providing several benefits in the q

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Scully, Ralph. "Mechanisms in transplantation tolerance." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321084.

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Tiosso, Caio de Faria [UNESP]. "Caracterização da resposta imune celular pela expressão imunoistoquímica de CD4, CD8, CD28, CD152, CD56 e FOXP3 em carcinoma mamário de fêmeas caninas." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/89004.

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Made available in DSpace on 2014-06-11T19:23:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-02-28Bitstream added on 2014-06-13T20:11:24Z : No. of bitstreams: 1 tiosso_cf_me_jabo.pdf: 436744 bytes, checksum: 79836ae4ce26da0a2ba481a0fe57e375 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>O estudo dos tumores mamários em cadelas revela-se como um excelente modelo para a investigação das neoplasias mamárias em mulheres e tanto no homem quanto nos animais a resposta imune pode interferir no desenvolvimento de neoplasias. Este trabalho teve como objetivo avali

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Tiosso, Caio de Faria. "Caracterização da resposta imune celular pela expressão imunoistoquímica de CD4, CD8, CD28, CD152, CD56 e FOXP3 em carcinoma mamário de fêmeas caninas /." Jaboticabal, 2012. http://hdl.handle.net/11449/89004.

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Orientador: Wilter Ricardo Russiano Vicente<br>Banca: Maricy Apparicio Ferreira<br>Banca: Marcela Marcondes Pinto Rodrigues<br>Resumo: O estudo dos tumores mamários em cadelas revela-se como um excelente modelo para a investigação das neoplasias mamárias em mulheres e tanto no homem quanto nos animais a resposta imune pode interferir no desenvolvimento de neoplasias. Este trabalho teve como objetivo avaliar a eficácia e estimulação do sistema imune celular em tumores mamários de fêmeas caninas por meio da expressão de CD4, CD8, CD4+CD25+ (Foxp3), CD28, CD152 e CD56 (NK). A avaliação da express

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43

Behrendt, Anne [Verfasser], and Reinhard [Akademischer Betreuer] Obst. "Differential antigen dependency of CD4+ and CD8+ T cells / Anne Behrendt. Betreuer: Reinhard Obst." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2014. http://d-nb.info/1055907378/34.

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Maroun, Christiane. "Distinct mechanisms regulate antigen receptor mediated signalling in CD4+ and CD8+ primary T cells." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=39960.

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For the last two decades, available results have suggested that CD4 and CD8 are functional analogs which, expressed in a mutually exclusive fashion, have provided a fundamental basis for the characterization of the two T cell lineages. This functional analogy has been described during both T cell development and maturation, as well as during the activation of mature peripheral T lymphocytes. It has been demonstrated that the stringency for CD4/CD8 expression, and their ability to interact with MHC molecules during positive and negative selection, are comparable. Further, mAb mediated coaggrega

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English, Kieran. "Deciphering the cellular mechanisms promoting CD4+ T cell-dependent intrahepatic CD8+ T cell immunity." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/27735.

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The liver is the body’s largest internal organ and assumes many important physiological and metabolic functions. It is also well-established that the liver possesses unique immunological properties and a delicate balance between tolerance and immunity exists within this large organ. CD4 T cell help to CD8 T cells has emerged as a critical factor involved in promoting robust CD8 T cell responses against viral and tumour antigens. Studies in humans and chimpanzees indicate that CD4 T cells are critical for strong intrahepatic CD8 T cell responses and the spontaneous control of hepatitis C virus

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DiSanto, James Philip. "Molecular events in human T cell activation : CD4, CD8 and the human Lyt-3 molecules /." Access full-text from WCMC, 1989. http://proquest.umi.com/pqdweb?did=745024391&sid=1&Fmt=2&clientId=8424&RQT=309&VName=PQD.

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Mossu, Adrien. "Régulation de la survie des cellules dendritiques plasmacytoïdes dans un contexte inflammatoire non viral." Thesis, Besançon, 2015. http://www.theses.fr/2015BESA3011/document.

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Les cellules dendritiques plasmacytoïdes (pDC) sont spécialisées dans la lutte antivirale, notamment grâce à leur capacité à sécréter des IFN de type I. Néanmoins, elles sont aussi impliquées dans Pactivation des réponses immunitaires adaptatives, et des lymphocytes T (LT) en particulier. C'est pourquoi, lors d'épisodes inflammatoires chroniques ou incontrôlés, les pDC sont à l'origine de l'initiation ou du maintien de syndromes inflammatoires et du développement de pathologies auto-immunes. Il doit donc exister des mécanismes permettant de contrôler l'activité de ces cellules. À l'aide d'un m

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Hambor, John Edward. "Bifunctionality of the human CD8 molecule." Case Western Reserve University School of Graduate Studies / OhioLINK, 1990. http://rave.ohiolink.edu/etdc/view?acc_num=case1054916413.

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Sepulveda, Homero. "Activation requirements for CD8 T cells /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1998. http://wwwlib.umi.com/cr/ucsd/fullcit?p9907780.

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Arantza, Beatriz Nájera Ramírez. "Análisis de los resultados de carga viral y conteo celular de CD4 y CD8 en muestras sanguíneas recibidas de enero a diciembre del 2016 en el laboratorio clínico del centro médico ISSEMyM." Tesis de Licenciatura, Universidad Autónoma del Estado de México, Universidad CUI Ixtlahuaca, 2018. http://hdl.handle.net/20.500.11799/70658.

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Introducción. La infección por VIH se encuentra presente en México desde el año 1983, desde esa fecha a la actualidad, ha constituido un problema de salud pública, los pacientes diagnosticados requieren de pruebas como la carga viral la cual sirve para determinar la cantidad de VIH que hay en la sangre y el conteo de células CD4 y CD8 que son indicadores para valorar la respuesta inmune del paciente. Objetivo. Analizar los resultados de carga viral y conteo celular CD4 y CD8 en pacientes adultos del Centro Médico ISSEMyM en el periodo comprendido de Enero 2016 a Diciembre 2016. Material y Méto

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